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| Product | Description | |
|---|---|---|
| Apigenin | Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a K i of 2 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 4',5,7-Trihydroxyflavone; Apigenol; C.I. Natural Yellow 1. CAS No. 520-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N1201. |  |
| Apigenin | 1g Pack Size. Group: Aroma Chemicals, Building Blocks, Organics. Formula: C15H10O5. CAS No. 520-36-5. Prepack ID 22930039-1g. Molecular Weight 270.24. See USA prepack pricing. |  |
| Apigenin | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsfood additives, flavours & adulterants. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4',5,7-Trihydroxyflavone, Pelargidenon 1449. |  |
| Apigenin | Apigenin. Group: Biochemicals. Grades: Purified. CAS No. 520-36-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Apigenin (4',5,7-Trihydroxyflavone) | Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignan. Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyflavone. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Apigenin 4'-β-D-glucuronide Triacetate Methyl Ester | Apigenin 4'-β-D-glucuronide Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Synonyms: Apigenin 4'-β-D-Gucopyranoside Triacetate Methyl Ester. Molecular formula: C28H28O14. Mole weight: 588.51. |  |
| Apigenin 4'-O- β-D-Glucuronide | Flavone component of the aerial parts of alfalfa (Medicago sativa L.) and pyrethrum flowers (Chrysanthemum cinerarifolium). Apigenin 4'-O- β-D-Glucuronide can be utilized for food or feed use and biological study of chemical composition of protein-xanthophyll concentrate dietary supplement made from alfalfa. Group: Biochemicals. Grades: Highly Purified. CAS No. 51771-57-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H18O11, Molecular Weight: 446.36. US Biological Life Sciences. | Worldwide |
| apigenin 4'-O-methyltransferase | Converts apigenin into acacetin. Naringenin can also act as an acceptor, but more slowly. Group: Enzymes. Synonyms: flavonoid O-methyltransferase; flavonoid methyltransferase; S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.75. CAS No. 118251-36-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1976; apigenin 4'-O-methyltransferase; EC 2.1.1.75; 118251-36-8; flavonoid O-methyltransferase; flavonoid methyltransferase; S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Cat No: EXWM-1976. |  |
| Apigenin-4'-O-sulfate Potassium Salt | Apigenin-4'-O-sulfate Potassium Salt is a sulfated form of Apigenin (A726500) flavone, present in numerous plant species. Group: Biochemicals. Grades: Highly Purified. CAS No. 120537-28-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H9KO8S, Molecular Weight: 388.39. US Biological Life Sciences. | Worldwide |
| Apigenin 6,8-di-C-glucoside | Vicenin -2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Synonyms: Vicenin II; Vicenin 2; Violantin. Grade: >98%. CAS No. 23666-13-9. Molecular formula: C27H30O15. Mole weight: 594.5. | |
| Apigenin 6-C-α-L-arabinopyranosyl-8-C- β-D-xylopyranoside | Apigenin 6-C-α-L-arabinopyranosyl-8-C- β-D-xylopyranoside. Group: Biochemicals. CAS No. 677021-30-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Apigenin 6-glucosyl-7-O-methyl ether | Apigenin 6-glucosyl-7-O-methyl ether. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SWERTISIN;APIGENIN 6-GLUCOSYL-7-O-METHYL ETHER;4',5-Dihydroxy-7-methoxy-6-β-D-glucopyranosylflavone;6-(β-D-Glucopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one. Product Category: Heterocyclic Organic Compound. CAS No. 6991-10-2. Molecular formula: C22H22O11. Mole weight: 462.4. Product ID: ACM6991102. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Apigenin 7-β-D-glucuronide Triacetate Methyl Ester | Apigenin 7-β-D-glucuronide Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Synonyms: Apigenin 7-β-D-Gucopyranoside Triacetate Methyl Ester. Molecular formula: C28H28O14. Mole weight: 588.51. | |
| Apigenin 7- β-D-Gucopyranoside Triacetate Methyl Ester | Apigenin 7- β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin (I819700), a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C28H28O14, Molecular Weight: 588.51. US Biological Life Sciences. | Worldwide |
| Apigenin 7-glucoside | Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigetrin. CAS No. 578-74-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0578. | |
| Apigenin 7-glucoside | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. | |
| Apigenin-7-glucuronide | Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 ?M for MMP-3, MMP-8, MMP-9, MMP-13, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Apigenin 7-O-glucuronide. CAS No. 29741-09-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1454. | |
| Apigenin 7-O- (2G-rhamnosyl) gentiobioside | Apigenin 7-O- (2G-rhamnosyl) gentiobioside. Group: Biochemicals. CAS No. 174284-20-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Apigenin-7-O - (2G-rhamnosyl) gentiobioside | Apigenin-7-O - (2G-rhamnosyl) gentiobioside. Group: Biochemicals. Alternative Names: Apigenin 7- (2G-rhamnosyl) gentiobioside. Grades: Plant Grade. CAS No. 174284-20-9. Pack Sizes: 10mg. Molecular Formula: C33H40O19, Molecular Weight: 740.66. US Biological Life Sciences. | Worldwide |
| Apigenin 7-O-glucuronide | Apigenin 7-O-glucuronide. Group: Biochemicals. CAS No. 29741-09-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Apigenin 7-O-glucuronide | primary reference standard. Group: Herbal medicinal products standards. | |
| Apigenin-7-O-glucuronide | Apigenin-7-O-glucuronide. Group: Biochemicals. Grades: Plant Grade. CAS No. 29741-09-1. Pack Sizes: 10mg. Molecular Formula: C21H18O11, Molecular Weight: 446.36. US Biological Life Sciences. | Worldwide |
| Apigenin 7-O-methylglucuronide | Apigenin 7-O-methylglucuronide is a flavonoid glycoside isolated from Physocarpus capitatus. Synonyms: (2S,3S,4S,5R,6S)-Methyl 3,4,5-trihydroxy-6-((5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylate. Grade: 98.0%. CAS No. 53538-13-9. Molecular formula: C22H20O11. Mole weight: 460.4. | |
| Apigenin-[d5] | Apigenin-[d5] is the labelled analogue of Apigenin, which is the main active ingredient of Chamomil extract. Chamomile is rich in flavonoid active ingredients, which has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. Synonyms: Apigenin D5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5; 4',5,7-Trihydroxyflavone-d5; Pelargidenon 1449-d5; [3,6,8,3',5'-d5]-Apigenin. Grade: ≥96%. CAS No. 263711-74-6. Molecular formula: C15H5D5O5. Mole weight: 275.27. | |
| Apigenin-d5 7-Glucuronide | Apigenin-d5 7-Glucuronide is labelled Apigenin 7-Glucuronide (A726505), a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C21H13D5O11, Molecular Weight: 451.39. US Biological Life Sciences. | Worldwide |
| Apigenin-d5 (Major) | The labeled aglucon of apiin and of apigenin-7-glucoside. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5; 4',5,7-Trihydroxyflavone-d5; Pelargidenon 1449-d5; [3,6,8,3,5-d5]-Apigenin. Grades: Highly Purified. CAS No. 263711-74-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Apigeninidin chloride | analytical standard. Group: Chemical class. | |
| Apigenin Liposome | Apigenin (AP) is a natural flavonoid with a variety of biological activities such as antioxidant, anti-inflammatory, anti-cancer and autoimmunity. This product is a pre-formulated liposome encapsulating Apigenin. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Apigetrin (Apigenin-7-O-glucoside) | Apigetrin (Apigenin-7-O-glucoside). Group: Biochemicals. Alternative Names: Apigenin 7-O-glucoside; Cosmetin. Grades: Plant Grade. CAS No. 578-74-5. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.38. US Biological Life Sciences. | Worldwide |
| AP-III-a4 | AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC 50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENOblock. CAS No. 1177827-73-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858. | |
| AP-III-a4 | AP-III-a4, also known as ENOblock, is the first, nonsubstrate inhibitor of enolase, blocking cancer cell metastasis in vivo. biochemical analysis showed that the half maximal inhibitory concentration (IC50) of enolase inhibition by ENOblock is 0.576 μM. ENOblock can inhibit cancer cell metastasis in vivo. Moreover, an unexpected role for enolase in glucose homeostasis was revealed by in vivo analysis. ENOblock is the first reported enolase inhibitor that is suitable for biological assays. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AP-III-a4; ENOblock. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.74. Purity: >98%. IUPACName: N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-4-[[4-[(cyclohexylmethyl)amino]-6-[[(4-fluorophenyl)methyl]amino]-1,3,5-triazin-2-yl]amino]benzeneacetamide. Canonical SMILES: O=C(NCCOCCOCCN)CC1=CC=C(NC2=NC(NCC3CCCCC3)=NC(NCC4=CC=C(F)C=C4)=N2)C=C1. Product ID: ACM1177827734. Alfa Chemistry ISO 9001:2015 Certified. | |
| AP-III-a4 | AP-III-a4 is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM); inhibit cancer cell metastasis in vivo. Synonyms: ENOblock. Grade: >98%. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.72. | |
| AP-III-a4 hydrochloride | AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC 50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENOblock hydrochloride. CAS No. 2070014-95-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858A. | |
| Apiin | Apiin. Group: Biochemicals. Grades: Plant Grade. CAS No. 26544-34-3. Pack Sizes: 20mg. Molecular Formula: C26H28O14, Molecular Weight: 564.49. US Biological Life Sciences. | Worldwide |
| Apiin | Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC 50 = 0.08 mg/mL) in-vitro and iNOS expression (IC 50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 26544-34-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0577. | |
| Apilimod | Apilimod is a potent and orally bioavailable inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: STA-5326; STA 5326; STA5326; N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grade: 99%. CAS No. 541550-19-0. Molecular formula: C23H26N6O2. Mole weight: 418.49. | |
| Apilimod | Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC 50 s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively [1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STA 5326; LAM-002A free base; AIT-101. CAS No. 541550-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14644. | |
| Apilimod mesylate | Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC 50 s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively [1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STA 5326 mesylate; LAM-002A; AIT-101 mesylate. CAS No. 870087-36-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14644A. | |
| Apilimod mesylate | The mesylate salt form of Apilimod. Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: methanesulfonic acid N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grade: 98%. CAS No. 870087-36-8. Molecular formula: C23H26N6O2.2CH4O3S. Mole weight: 610.7. | |
| Apimostinel | Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Synonyms: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel; (2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grade: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60. | |
| Apimostinel | Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NRX-1074; AGN-241660. CAS No. 1421866-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102053. | |
| a-Pinene oxide | a-Pinene oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,3-epoxy-pinan. Product Category: Epoxide Monomers. CAS No. 1686-14-2. Molecular formula: C10H16O. Mole weight: 152.23 g/mol. Purity: 0.97. Product ID: ACM-MO-1686142. Alfa Chemistry ISO 9001:2015 Certified. Categories: alpha-Pinene oxide, A-pinene-oxide decyclase. | |
| a-Pinene oxide | a-Pinene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1686-14-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Apinocaltamide | Apinocaltamide (ACT-709478) is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 is used in the research of generalized epilepsies [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-709478. CAS No. 1838651-58-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112723. | |
| APIO-EE-07 | APIO-EE-07 is a dual-target inhibitor of RSK1 and MSK2. It was shown to suppress colon cancer cell growth and anchorage-independent growth. Synonyms: 5-Fluoro-3-(4-(4-nitrophenyl)-2-oxobut-3-enylidene)indolin-2-one. Grade: 98%. CAS No. 1606160-46-6. Molecular formula: C18H11FN2O4. Mole weight: 338.29. | |
| Apiogalacturonan | Apiogalacturonan is a pectin found in the walls of Lemna and Zostera marina. Apiogalacturonan, depicted as a remarkable bioactive polysaccharide deeply rooted in the plant kingdom, showcasing immense promise application in studying diverse ailments such as malignancies, diabetes and cardiovascular afflictions. Synonyms: Galacturonoapian. CAS No. 9039-3-6. | |
| Apioline | Apioline. Group: Biochemicals. Alternative Names: 4,7-Dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole; Apiole; 1-Allyl-2, 5-dimethoxy-3, 4- (methylenedioxy) benzene; 1,2-Methylenedioxy-3,6-dimethoxy-4-allylbenzene; 1-Allyl-2,5-dimethoxy-3,4-methylenedioxybenzene; 4,7-Dimethoxy-5-(2-propenyl)-1,3-benzodioxole; 5-Allyl-4,7-dimethoxy-1,3-benzodioxole; Apiol; Apioline; NSC 9070; Parsley Apiole; Parsley Camphor; Petersilienapiol. Grades: Highly Purified. CAS No. 523-80-8. Pack Sizes: 25mg. Molecular Formula: C12H14O4, Molecular Weight: 222.24. US Biological Life Sciences. | Worldwide |
| Apiopaeonoside | Apiopaeonoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 100291-86-9. Pack Sizes: 20mg. Molecular Formula: C20H28O12, Molecular Weight: 460.43. US Biological Life Sciences. | Worldwide |
| apiose 1-reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-apiitol:NAD+ 1-oxidoreductase. Other names in common use include D-apiose reductase, and D-apiitol reductase. Group: Enzymes. Synonyms: D-apiose reductase; D-apiitol reductase. Enzyme Commission Number: EC 1.1.1.114. CAS No. 37250-45-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0017; apiose 1-reductase; EC 1.1.1.114; 37250-45-6; D-apiose reductase; D-apiitol reductase. Cat No: EXWM-0017. | |
| Apitegromab | Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SRK-015. CAS No. 2278276-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99441. | |
| Apitolisib | Apitolisib, also known as GDC-0980 and RG7422; or GNE390, is a dual PI3 kinase/mTOR inhibitor, is also an orally available agent targeting phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. PI3K/mTOR kinase inhibitor GDC-0980 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy; mTOR, a serine/threonine kinase downstream of PI3K, may also be activated in a PI3K-independent fashion. Synonyms: GDC-0980; GDC0980; GDC 0980; RG7422; RG-7422; RG 7422; GNE 390; GNE390; GNE-390; Apitolisib. CAS No. 1032754-93-0. Molecular formula: C23H30N8O3S. Mole weight: 498.606. | |
| Apitolisib | Apitolisib (GDC-0980; GNE 390; RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase ( TORC1 / 2 ) inhibitor with IC 50 s of 5 nM/27 nM/7 nM/14 nM for PI3Kα /PI3Kβ /PI3Kδ /PI3Kγ , and with a K i of 17 nM for mTOR. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0980; GNE 390; RG 7422. CAS No. 1032754-93-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13246. | |
| Apixaban | Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with K i of 0.08 nM and 0.17 nM in human and rabbit, respectively [1]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-562247-01. CAS No. 503612-47-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50667. | |
| Apixaban | Apixaban (INN, trade name Eliquis) is an anticoagulant for the prevention of venous thromboembolism and the prevention of stroke in atrial fibrillation. It is a direct factor Xa inhibitor. Apixaban has been available in Europe since May 2011. The drug was developed in a joint venture by Pfizer and Bristol-Myers Squibb. Uses: Factor xa inhibitors. Synonyms: BMS-562247-01; BMS 562247-01; BMS562247-01; brand name: Eliquis. Grade: 0.98. CAS No. 503612-47-3. Molecular formula: C25H25N5O4. Mole weight: 459.506. | |
| Apixaban | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C25H25N5O4. CAS No. 503612-47-3. Prepack ID 70419224-100mg. Molecular Weight 459.5. See USA prepack pricing. | |
| Apixaban-[13C,d3] | Apixaban-[13C,d3] is the labelled analogue of Apixaban. Apixaban is an anticoagulant for the prevention of venous thromboembolism and the prevention of stroke in atrial fibrillation. It is a direct factor Xa inhibitor. Synonyms: Apixaban-13C,D3; 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide-13C,d3; BMS 562247-01-13C,d3; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Amide-13C,d3; Eliquis-13C,d3. Grade: ≥96% by HPLC; 99% atom 13C; 99% atom D. CAS No. 1261393-15-0. Molecular formula: C24[13C]H22D3N5O4. Mole weight: 463.52. | |
| Apixaban-13C,d3 | Apixaban- 13 C,d 3 is a deuterium and 13 C labeled Apixaban. Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BMS-562247-01- 13 C,d3. CAS No. 1261393-15-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-50667S. | |
| Apixaban Acid | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; Apixaban Impurity 41. CAS No. 503614-92-4. Molecular formula: C25H24N4O5. Mole weight: 460.5. | |
| Apixaban Acid-[13C,d3] | Apixaban Acid-[13C,d3] is the labelled analogue of Apixaban Acid, which is an intermediate of the synthesis of Apixaban, an inhibitor of blood coagulation factor Xa. Synonyms: Apixaban Acid-13C,D3; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid-13C,d3; Apixaban carboxylic acid-13C,d3. Grade: ≥99% by HPLC; 99% atom 13C; 99% atom D. Molecular formula: C24[13C]H21D3N4O5. Mole weight: 464.49. | |
| Apixaban Amine Amide Impurity | An impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; Apixaban Impurity 17. CAS No. 1423803-24-0. Molecular formula: C20H19N5O3. Mole weight: 377.40. | |
| Apixaban Amino Acid Impurity | It is an open ring impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: Apixaban open ring acid; Apixaban Open Chain Acid; 5-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic acid. CAS No. 2206825-87-6. Molecular formula: C25H27N5O5. Mole weight: 477.51. | |
| Apixaban Dehydro Impurity | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 4,5-Dehydro Apixaban; 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide. Grade: > 95%. CAS No. 1074549-89-5. Molecular formula: C25H23N5O4. Mole weight: 457.49. | |
| Apixaban Impurity 106 | Apixaban Impurity 106. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid. CAS No. 1704504-93-7. Molecular formula: C20H18N4O4. Mole weight: 378.38. Catalog: APB1704504937. | |
| Apixaban Impurity 14 | A metabolite of Apixaban. Synonyms: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid. Grade: > 95%. CAS No. 1704504-93-7. Molecular formula: C20H18N4O4. Mole weight: 378.39. | |
| Apixaban Impurity 15 | A metabolite of Apixaban. Synonyms: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester. Grade: > 95%. CAS No. 1466571-07-2. Molecular formula: C21H20N4O4. Mole weight: 392.42. | |
| Apixaban Impurity 17 | Apixaban Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one. CAS No. 1686149-78-9. Molecular formula: C21H27N3O3. Mole weight: 369.46. Catalog: APB1686149789. | |
| Apixaban Impurity 31 | An impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: Apixaban methyl ester and cyclic amide open chain methyl ester. CAS No. 2458079-10-0. Molecular formula: C27H30N4O6. Mole weight: 506.56. | |
| Apixaban Impurity 46 | An impurity of Apixaban, which is a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 3-chloro-1-(2-nitrophenyl)-1,2,5,6-tetrahydropyridin-2-one; 3-Chloro-1-(2-nitrophenyl)-5,6-dihydropyridin-2(1H)-one; Apixaban Related Compound 5. Grade: 95%. CAS No. 2219376-48-2. Molecular formula: C11H9ClN2O3. Mole weight: 252.65. | |
| Apixaban Impurity 6 | A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: Apixaban Acid Methyl Ester. Grade: > 95%. CAS No. 1074365-84-6. Molecular formula: C26H26N4O5. Mole weight: 474.52. | |
| Apixaban Impurity 9 | A metabolite of Apixaban. Synonyms: Apixaban V; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Ethyl Ester Ethyl 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyri. Grade: > 95%. CAS No. 503614-91-3. Molecular formula: C27H28N4O5. Mole weight: 488.55. | |
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