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| Product | Description | |
|---|---|---|
| Avimopan impurity 6 | Avimopan impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H31BrN2O4. Mole Weight: 503.44. Catalog: APB06655. |  |
| Avimopan impurity 7 | Avimopan impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H28ClNO. Mole Weight: 297.87. Catalog: APB06654. | |
| Avimopan impurity 8 | Avimopan impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H29NO3. Mole Weight: 367.49. Catalog: APB06657. | |
| Avimopan impurity 9 | Avimopan impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2280857-23-8. Molecular Formula: C25H32N2O4. Mole Weight: 424.54. Catalog: APB2280857238. | |
| Aviptadil | Aviptadil Acetate is an analog of vasoactive intestinal polypeptide (VIP) as Vasoactive intestinal peptide receptor agonists for the treatment of erectile dysfunction. Uses: Vasoactive intestinal peptide receptor agonists. Synonyms: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. Grades: 98%. CAS No. 40077-57-4. Molecular formula: C147H238N44O42S. Mole weight: 3325.80. |  |
| Aviptadil | Aviptadil is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine). CAS No. 40077-57-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0012. |  |
| Aviptadil acetate | Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide acetate salt (human, rat, mouse, rabbit, canine, porcine). CAS No. 1444827-29-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0012A. | |
| Avitinib | Avitinib (Abivertinib) is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC 50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R , EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abivertinib; AC0010. CAS No. 1557267-42-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19816. | |
| Avitinib | Avitinib (AC0010) is a third generation inhibitor of the EGFR (epidermal growth factor receptor) that was permitted parallel phase I clinical trials in the US. It is a pyrrolopyrimidine-based irreversible EGFR inhibitor that is mutation-selective with IC50 value of 0.18 nM against EGFR L858R/T790M double mutations. Upon oral administration, avitinib covalently binds to and inhibits the activity of mutant forms of EGFR. Uses: Tyrosine kinase inhibitors. Synonyms: AC0010. Grades: ≥98%. CAS No. 1557267-42-1. Molecular formula: C26H26FN7O2. Mole weight: 487.5. | |
| Avitinib maleate | Avitinib maleate, the maleate salt form of avitinib, is a pyrrolopyrimidine-based, irreversible epidermal growth factor receptor (EGFR) mutant-selective inhibitor (IC50 = 7.68 nM), with potential antineoplastic activity. Uses: Tyrosine kinase inhibitors. Synonyms: Avitinib maleate; AC0010MA; AC-0010MA; AC 0010MA; AC0010; AC-0010; AC 0010. CAS No. 1557268-88-8. Molecular formula: C30H30FN7O6. Mole weight: 603.6. | |
| Avitinib maleate | Avitinib (Abivertinib) maleate is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC 50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R , EGFR T790M and wild-type EGFR. Avitinib maleate is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib maleate shows anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abivertinib maleate; AC0010 maleate. CAS No. 1557268-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19816A. | |
| Avitriptan | Avitriptan is an antimigraine drug of the triptan family which was never marketed. It acts as a 5-HT1B and 5-HT1D receptor agonist. Synonyms: 1-[3-[3-[4-(5-methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indol-5-yl]-N-methyl-methanesulfonamide. Grades: > 95%. CAS No. 151140-96-4. Molecular formula: C22H30N6O3S. Mole weight: 458.59. | |
| Avizafone Dihydrobromide | Avizafone Dihydrobromide is a prodrug of Diazepam, which is a benzodiazepine used as an anti-anxiety and muscle relaxant, as well as to treat epilepsy. Synonyms: L-Lysyl-N-(2-benzoyl-4-chlorophenyl)-N-methyl-glycinamide Dihydrobromide; Prodiazepam Dihydrobromide; N-[3-(2-Benzoyl-4-chlorophenyl)-2-oxobutyl]-L-lysinamide Dihydrobromide. Grades: ≥95%. CAS No. 60067-15-4. Molecular formula: C22H29Br2ClN4O3. Mole weight: 592.75. | |
| Avizakimab | Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BOS161721. CAS No. 2229685-51-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99451. | |
| AVL-292 | AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. Uses: Protein kinase inhibitors. Synonyms: CC-292; CC292; CC 292; AVL292; AVL 292; spebrutinib. Grades: 98%. CAS No. 1202757-89-8. Molecular formula: C22H22FN5O3. Mole weight: 423.44. | |
| AVL-292 benzenesulfonate | AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed. Synonyms: Spebrutinib besylate; CC-292 besylate; AVL-292 benzenesulfonate; CC 292 besylate; AVL 292 benzenesulfonate; CC292 besylate; AVL292 benzenesulfonate. Grades: >98%. CAS No. 1360053-81-1. Molecular formula: C28H28FN5O6S. Mole weight: 581.62. | |
| AVN-101 hydrochloride | AVN-101 is an antagonist of the serotonin (5-HT) receptor subtypes 5-HT7, 5-HT2C, 5-HT2A, and 5-HT6 (Kis = 0.153, 1.17, 1.56, and 2.04 nM, respectively). It is also an antagonist of α2A-, α2B-, α2C-, α1B-, α1A-, and α1D-adrenergic receptors (Kis = 0.41, 1.77, 3.55, 9.4, 18.9, and 30.2 nM, respectively), as well as histamine H1 and H2 (Kis = 0.58 and 89 nM, respectively), but not H3, receptors. It is a multi-target drug candidate for the treatment of CNS disorders. Synonyms: 2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride; AVN-101 HCl; 1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-, hydrochloride (1:1); 2,8-dimethyl-5-(2-phenylethyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride; 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-1H-pyrido[4,3-b]indole, monohydrochloride. Grades: ≥95%. CAS No. 1061354-48-0. Molecular formula: C21H25ClN2. Mole weight: 340.90. | |
| AVN-101 hydrochloride | AVN-101 hydrochloride is a potent, brain-penetrant and orally active 5-HT7 receptor antagonist ( K i of 153 pM), with slightly lesser potency toward 5-HT6 , 5-HT2A , and 5HT-2C receptors ( K i values of 2.04 nM, 1.56 ?nM, and 1.17? nM, respectively). AVN-101 hydrochloride also exhibits a rather high affinity toward histamine H1 ( K i of 0.58 nM) and adrenergic α2A , α2B , and α2C (Ki= 0.41-3.6 nM) receptors. AVN-101 hydrochloride can be studied in such diseases as general anxiety disorders, depression, schizophrenia, and multiple sclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1061354-48-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117046A. | |
| AVN-211 | This active molecular is a Selective 5-HT6 Receptor antagonist, for the treatment of Alzheimer's Disease under development by by Avineuro Pharmaceuticals. AVN-211 shows good anxiolytic efficacy, low toxicity ,no side effects in vivo, an appropriate pharmacokinetic profile and good stability. AVN-211 significantly delayed or partially halted the progressive decline in memory function associated with AD and this efficacy makes it an interesting drug candidate for the treatment of neurodegenerative and psychiatric disorders. In Jul 2015, Avineuro Pharmaceuticals completed a phase II trial in Schizophrenia in USA and planed a trial for Alzheimer's disease in USA. In Aug 2015, Phase-II development was ongoing for Schizophrenia in USA. Uses: Alzheimer's disease;schizophrenia. Synonyms: AVN-211; AVN 211; AVN211; CD-008-0173. 5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine,CD-008-0173. Grades: 98%. CAS No. 1173103-84-8. Molecular formula: C15H15N3O2S2. Mole weight: 333.42. | |
| AVN-492 | AVN-492 is a novel potent and selective 5-HT6 receptor antagonist with Ki values of 91 pM and 170 nM for 5-HT6R and 5-HT2BR, respectively. Uses: Serotonin antagonists. Synonyms: AVN-492; AVN 492; AVN492. 3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine. CAS No. 1220646-23-0. Molecular formula: C17H21N5O2S. Mole weight: 359.45. | |
| AVN-944 | AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanosine triphosphate (GTP), a purine molecule required for DNA and RNA synthesis. AVN944 appears to have a selective effect on cancer cells in that deprivation of GTP in normal cells results in a temporary slowing of cell growth only. Synonyms: code name: AVN 944; AVN944; VX-944; VX 944; VX944. Grades: 0.98. CAS No. 297730-17-7. Molecular formula: C25H27N5O5. Mole weight: 477.51. | |
| Avobenzone | Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70356-09-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0316. | |
| Avobenzone | Oil-soluble UVA filter. Ability to absorb ultraviolet light over a wider range of wavelengths than many other sunscreen agents. Absorption maximum of 357 nm. Uses: Sun care products, baby sun care products, daily sun protection, decorative cosmetics. Group: Heterocyclic organic compound. Alternative Names: Butyl methoxydibenzoylmethane. CAS No. 70356-09-1. Molecular formula: C20H22O3. Mole weight: 310.4. Appearance: Off-white to yellowish, crystalline powder, weak odor. Purity: 97-104%. Density: 1.079. Catalog: ACM70356091. |  |
| Avobenzone | Avobenzone. Group: Biochemicals. Alternative Names: 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione; Butyl methoxydibenzoyl methane . Grades: Highly Purified. CAS No. 70356-09-1. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C20H22O3. US Biological Life Sciences. |  Worldwide |
| Avobenzone | Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. Synonyms: Avobenzonum; Parsol 1789; Parsol1789; Parsol-1789; HSDB 7423; HSDB-7423; HSDB7423; 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-; 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione; 1-(4'-tert-Butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione; 3-(4-Methoxyphenyl)-1-(4-tert-butylphenyl)-1,3-propanedione; 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane; 4-Methoxy-4'-tert-butyldibenzoylmethane; 4-tert-Butyl-4'-methoxydibenzoylmethane; Butylmethoxydibenzoylmethane; Escalol 517; Eusolex 9020; Milestab 1789; NeoHeliopan 357; Parsol 1789; Parsol A; Parsol RTM 1789; Photoplex; Solarom BMBM; Uvinul BMBM. Grades: >98%. CAS No. 70356-09-1. Molecular formula: C20H22O3. Mole weight: 310.39. | |
| AVOCADAMIDE DEA | Heterocyclic Organic Compound. CAS No. 124046-21-5. Catalog: ACM124046215. | |
| Avocado Butter | Natural avocado seed oil extracted from the flesh of the avocado fruit, combined with soybean lipids and beeswax to a creamy texture. Uses: Creams, lotions, pomades, lip balms, lipsticks, hair pomades, makeup products, conditioners. Group: Skin actives. CAS No. 8024-32-6/8012-89-3. Appearance: Soft, creamy butter, no odor. Catalog: CI-SC-0988. | |
| Avocado Extract | Extract obtained from Persea Gratissima (Avocado) fruits. Contains 20% extract dissolved in water and glycerin. Contains high amounts of vitamin B2, D, A, E and K and potassium. Has anti-irritating and soothing properties and is often used as skin-nutrient. Uses: Creams, lotions, masks and hair care products. Group: Skin actives. CAS No. 7732-18-5/56-81-5/8024-32-6/122-99-6. Appearance: Pale to medium yellow liquid, characteristic odor. Catalog: CI-SC-0795. | |
| Avocado Extract | Avocado Extract. Applications: Used for health care products, dietary supplements, herb medicine and cosmetic industry. Group: Others. Synonyms: Avocado Extract; Persea americana L. Purity: 30% Total Phytosterol by UV. Appearance: Yellow Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Persea americana L. Avocado Extract; Persea americana L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-122. |  |
| Avocado Oil | Avocado Oil. CAS No. 8024-32-6. VIGON Item # 507697. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers, Cosmetics. |  America & Internationally |
| Avocado Powder | Avocado powder takes avocado as raw material, adopts spray drying technology, low temperature physical grinding technology, instant grinding, to obtain edible high quality avocado powder. Product ID: CDF4-0226. Category: Flavour. Product Keywords: Flavor Enhancers; Avocado Powder; CDF4-0226; Flavour;. Grade: Food Grade. Color: White powder. Physical State: powder. Storage: Room Temperature. Applications: It is widely used in processing various avocado flavored foods and added to various nutritional foods. |  |
| Avoralstat | Avoralstat, also known as BCX-4161, is an oral plasma kallikrein (PKK) inhibitor and Bradykinin inhibitor, used to treat hereditary angioedema. Synonyms: 3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine-2-carboxylic acid; BCX-4161; BCX 4161; BCX4161; Avoralstat. CAS No. 918407-35-9. Molecular formula: C28H27N5O5. Mole weight: 513.54. | |
| Avosentan | Avosentan is a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma. Group: Biochemicals. Alternative Names: N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 67-0565; SPP 301. Grades: Highly Purified. CAS No. 290815-26-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avosentan | Avosentan, also known as SPP301, R-639, and RO 67-0565, is a potent and selective endothelin receptor(ETA receptor) antagonist. Synonyms: N-[6-methoxy-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-yl]-5-methylpyridine-2-sulfonamide;Avosentan;290815-26-8;UNII-L94KSX715K;SPP301; SPP301; SPP301; RO 67-0565; RO-67-0565; RO67-0565; R-639; Avosentan. Grades: 95%. CAS No. 290815-26-8. Molecular formula: C23H21N5O5S. Mole weight: 479.51. | |
| Avrainvillamide | Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found in A. ochraceus. It is active against S. aureus, S. pyogenes, and E. faecalis (MICs = 12.5, 12.5, and 25 μg/ml, respectively). Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50 values of 0.24, 0.62, 0.21, and 0.41 μM, respectively. Synonyms: CJ-17,665; CJ17,665; CJ 17,665; 3,11,12,13,13aS,14-hexahydro-3,3,14,14-tetramethyl-8H,10H-7aS,12aS-(iminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazole-8,16-dione 15-oxide. Grades: >95% by HPLC. CAS No. 269741-97-1. Molecular formula: C26H27N3O4. Mole weight: 445.52. | |
| Avridine | A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Group: Biochemicals. Alternative Names: 2, 2'- [ [3- (Dioctadecylamino) propyl] imino] bisethanol; CP 20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane; N, N-Dioctadecyl-N', N'-bis (2-hydroxyethyl) propanediamine. Grades: Highly Purified. CAS No. 35607-20-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avridine | Avridine is a potent synthetic non-immunogenic adjuvant that used to induce arthritis in Lewis (LEW) and DA rats. Uses: A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Synonyms: CP 20961; CP20961; CP-20961;N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane. Grades: ≥98%. CAS No. 35607-20-6. Molecular formula: C43H90N2O2. Mole weight: 667.19. | |
| Avutometinib | Avutometinib (Ro 5126766) is a first-in-class dual MEK / RAF inhibitor that allosterically inhibits BRAF V600E , CRAF , MEK , and BRAF (IC 50 : 8.2, 56, 160 nM, and 190 nM, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 5126766; CH5126766. CAS No. 946128-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18652. | |
| AVX 13616 | AVX 13616 shows the potent in vivo antibacterial activity of Avexa's lead antibacterial candidate, particularly against drug-resistant Staphylococcus pathogens. It was as active as mupirocin in a nasal decolonization model but required only a single application. It showed broad spectrum antibacterial activity against a range of isolates with MICs of 2-4 micrograms per millilitre against S. aureus, coagulase negative staphylococci, enterococci, MRSA, VISA and VRSA. Synonyms: AVX-13616; AVX 13616; AVX13616. Grades: >98%. CAS No. 900814-48-4. Molecular formula: C50H73Cl2N7O7. Mole weight: 955.06. | |
| Avycaz | Avycaz is a fixed-dose combination medication composed of ceftazidime, a cephalosporin antibiotic, and avibactam, a β-lactamase inhibitor. Synonyms: ceftazidime & avibactam; ceftazidime + avibactam; Avibactam / Ceftazidime. CAS No. 1393723-27-7. Molecular formula: C29H33N9O13S3. Mole weight: 811.8. | |
| Awamycin | Awamycin is produced by the strain of Streptomyces sp. No. 80-217. It has anti-gram-positive bacteria and antitumor activity. Synonyms: Antibiotic Tan 528A; Protostreptovaricin I, 10,25-didemethyl-21-hydroxy-10-(methoxycarbonyl)-19-O-methyl-25-(methylthio)-; Protostreptovaricin-31-oic acid, 25-demethyl-21-hydroxy-19-O-methyl-2S-(methylthio)-, methyl ester. Molecular formula: C38H49NO12S. Mole weight: 743.86. | |
| Awd 122-60 | Heterocyclic Organic Compound. CAS No. 108610-89-5. Catalog: ACM108610895. | |
| AWD 12-281 | AWD 12-281 is a strong selective phosphodiesterase 4 (PDE4) inhibitor which has potent effects in models of lung inflammation using inhalative administration. Synonyms: N-(3,5-dichloropyridin-4-yl)-2-[1-[(4-fluorophenyl)methyl]-5-hydroxyindol-3-yl]-2-oxoacetamide; AWD 12-281; AWD12-281; AWD-12-281;UNII-550671J24D; GSK 842470; GSK 842470; GSK-842470. Grades: >98%. CAS No. 257892-33-4. Molecular formula: C22H14Cl2FN3O3. Mole weight: 458.27. | |
| AWD 131-138 | AWD 131-138 is a partial agonist of GABAA receptor with low affinity for the benzodiazepine binding site. AWD 131-138 exhibits potent anticonvulsant and anxiolytic properties in rodent models. It is used as an antiepileptic drug for the treatment of canine idiopathic epilepsy. Synonyms: AWD 131-138; AWD-131-138; AWD131-138; AWD 131138; Imepitoin; 3-(4-chlorophenyl)-5-morpholin-4-yl-4H-imidazol-2-one. CAS No. 188116-07-6. Molecular formula: C13H14ClN3O2. Mole weight: 279.724. | |
| AX-024 hydrochloride | AX-024 hydrochloride is an inhibitor of T cell receptor (TCR) that selectively inhibits the TCR-Nck interaction. By modulating TCR signaling, AX-024 prevents the development of psoriasis and asthma and, furthermore, exerts a long-lasting therapeutic effect in a model of autoimmune encephalomyelitis. Synonyms: 1-[[4-(4-Fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]pyrrolidine hydrochloride; Pyrrolidine, 1-[[4-(4-fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]-, hydrochloride (1:1). Grades: 99%. CAS No. 1704801-24-0. Molecular formula: C21H22FNO2.HCl. Mole weight: 375.86. | |
| AX 048 | Ethyl 4-[(2-oxohexadecanoyl)amino]butanoate (AX 048) is a PLA2 (Phospholipase A2) and PGE2 (Prostaglandin E2) inhibitor. PLA2 is known as calcium-dependent cytosolic PLA2 (cPLA2), which selectively releases arachidonic acid from membrane phospholipids. It plays a central role in initiating the synthesis of prostaglandins and leukotrienes. This compound also contains a specific affinity for group IVA cPLA2 which moderates antihyperalgesia effects. Synonyms: AX-048; AX 048; Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester; UNII-8782Z45DLV; 8782Z45DLV; Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester; ethyl 4-(2-oxohexadecanoylamino)butanoate; ethyl 4-(2-oxohexadecanamido)butanoate; CHEMBL574723; SCHEMBL4781039; DTXSID60236282; AKOS040755666; ethyl 4-[(2-oxohexadecanoyl)amino] butanoate; Q27269809; 4- [(1, 2- dioxohexadecyl)amino]- butanoic acid, ethyl ester. Grades: ≥98%. CAS No. 873079-69-7. Molecular formula: C22H41NO4. Mole weight: 383.6. | |
| AX-15836 | AX-15836 is a highly potent and selective ERK5 inhibitor (IC50 = 8 nM) with >1,000-fold selectivity for ERK5 over a panel of over 200 kinases. Synonyms: 2-[2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5-methyl-11-methylsulfonylpyrimido[4,5-b][1,4]benzodiazepin-6-one; AKOS030210962; ZINC669678933; AX15836; AX 15836; AX-15836. CAS No. 2035509-96-5. Molecular formula: C32H40N8O5S. Mole weight: 648.78. | |
| Axatilimab | Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SNDX-6352. CAS No. 2155851-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99452. | |
| AXC-715 | AXC-715 is a dual agonist of TLR7/TLR8. Synonyms: 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-; 4-Amino-2-butyl-1H-imidazo[4,5-c]quinoline-1-butanamine; 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine; AXC 715; AXC715. Grades: ≥95%. CAS No. 313350-31-1. Molecular formula: C18H25N5. Mole weight: 311.43. | |
| Axenomycin B | Axenomycin B is produced by the strain of Streptomyces lisandri F. I. 2604. It has antifungal, nematode and trichomonas activities. Molecular formula: C29H38O10. Mole weight: 546.60. | |
| Axillaridine A | Other Alkaloids. CAS No. 128255-16-3. Mole weight: 462.7. Purity: 95%+. Catalog: ACM128255163. | |
| Axinysone A | Axinysone A is a natural compound used in the research of cancer. Derived from natural sources, this product acts as a valuable inhibitor of specific signaling pathways involved in tumor growth and progression. Synonyms: (-)-Axinysone A. Grades: 97.5%. CAS No. 1114491-57-4. Molecular formula: C15H22O2. Mole weight: 234.338. | |
| Axinysone A | Terpenoids. CAS No. 1114491-57-4. Molecular formula: C15H22O2. Mole weight: 234.3. Appearance: Oil. Purity: 0.98. Catalog: ACM1114491574. | |
| Axinysone B | Axinysone B is a metabolite of the mushroom Anthracophyllum sp. BCC18695. Synonyms: (-)-Axinysone B; 2H-Cyclopropa[a]naphthalen-2-one, 1,1a,4,5,6,7,7a,7b-octahydro-4-hydroxy-1,1,7,7a-tetramethyl-, (1aS,4R,7S,7aS,7bR)-. Grades: 98.0%. CAS No. 1114491-60-9. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Axinysone B | Terpenoids. Alternative Names: 2H-Cyclopropa[A]Naphthalen-2-One, 1,1A,4,5,6,7,7A,7B-Octahydro-4-Hydroxy-1,1,7,7A-Tetramethyl-, (1As,4R,7S,7As,7Br)-. CAS No. 1114491-60-9. Molecular formula: C15H22O2. Mole weight: 234.33. Appearance: Powder. Purity: 0.98. IUPACName: (1aR,4S,7R,7aR,7bS)-4-hydroxy-1,1,7,7a-tetramethyl-1a,4,5,6,7,7b-hexahydrocyclopropa[a]naphthalen-2-one. Canonical SMILES: CC1CCC(C2=CC(=O)C3C(C12C)C3(C)C)O. Density: 1.11±0.1 g/cm3(Predicted). Catalog: ACM1114491609. | |
| Axitinib | Axitinib is a multi-targeted tyrosine kinase inhibitor with IC 50 s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1 , VEGFR2 , VEGFR3 and PDGFRβ , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-013736. CAS No. 319460-85-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10065. | |
| Axitinib | Axitinib. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Highly Purified. CAS No. 319460-85-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H18N4OS. US Biological Life Sciences. | Worldwide |
| Axitinib Acid (Axitinib Impurity 37) | Axitinib Acid (Axitinib Impurity 37). Uses: For analytical and research use. Group: Impurity standards. CAS No. 319462-34-5. Molecular Formula: C21H15N3O2S. Mole Weight: 373.43. Catalog: APB319462345. | |
| Axitinib-d3 | 2H Labeled Compounds. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. Catalog: ACM1126623899. | |
| Axitinib-d3 | Labeled analogue of Axitinib, a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. Group: Biochemicals. Alternative Names: N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Axitinib-D3 (Axitinib Impurity 36) | Axitinib-D3 (Axitinib Impurity 36). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1126623-89-9. Molecular Formula: C22H15D3N4OS. Mole Weight: 389.49. Catalog: APB1126623899. | |
| Axitinib Impurity 1 | Axitinib Impurity 1 is an impurity of Axitinib, a drug primarily used in the treatment of advanced renal cell carcinoma and metastatic thyroid cancer. Synonyms: Axitinib Impurity c. Grades: > 95%. CAS No. 885126-40-9. Molecular formula: C22H18N4OS. Mole weight: 386.48. | |
| Axitinib Impurity 10 | Axitinib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-N-methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 1443118-72-6. Molecular Formula: C29H25N5OS. Mole Weight: 491.61. Catalog: APB1443118726. | |
| Axitinib Impurity 11 | Axitinib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((1-acetyl-3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide. CAS No. 1639138-00-3. Molecular Formula: C17H14IN3O2S. Mole Weight: 451.28. Catalog: APB1639138003. | |
| Axitinib Impurity 12 | Axitinib Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((1H-indazol-6-yl)sulfinyl)-N-methylbenzamide. CAS No. 1959572-97-4. Molecular Formula: C15H13N3O2S. Mole Weight: 299.35. Catalog: APB1959572974. | |
| Axitinib Impurity 13 | Axitinib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-iodo-1H-indazol-6-yl)sulfinyl)-N-methylbenzamide. CAS No. 1443118-71-5. Molecular Formula: C15H12IN3O2S. Mole Weight: 425.24. Catalog: APB1443118715. | |
| Axitinib Impurity 14 | Axitinib Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-iodo-1H-indazol-6-yl)thio)-N-methylbenzamide. CAS No. 885126-34-1. Molecular Formula: C15H12IN3OS. Mole Weight: 409.24. Catalog: APB885126341. | |
| Axitinib Impurity 15 | Axitinib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-N-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 885126-40-9. Molecular Formula: C22H18N4OS. Mole Weight: 386.47. Catalog: APB885126409. | |
| Axitinib Impurity 16 | Axitinib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((1-acetyl-1H-indazol-6-yl)thio)-N-methylbenzamide. Molecular Formula: C17H15N3O2S. Mole Weight: 325.38. Catalog: APB01212. | |
| Axitinib Impurity 17 | Axitinib Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-methyl-2-((1-(2-(pyridin-2-yl)ethyl)-1H-indazol-6-yl)thio)benzamide. CAS No. 2749797-54-2. Molecular Formula: C22H20N4OS. Mole Weight: 388.49. Catalog: APB2749797542. | |
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