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| Product | Description | |
|---|---|---|
| Aurintricarboxylic acid | Aurintricarboxylic acid acts as a histological dye and an insulin-like growth factor receptor 1 antagonist. Synonyms: 1,4-cyclohexadiene-1-carboxylic acid, 3-(bis(3-carboxy-4-hydroxyphenyl)methylen; aluminon free acid. Grades: 95%. CAS No. 4431-00-9. Molecular formula: C22H14O9. Mole weight: 422.34. |  |
| Aurintricarboxylic acid | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs , with IC 50 s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively [1]. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase [2]. Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis [3]. Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway [4]. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC 50 of 0.6 μM [5]. Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC 50 of 0.47 μM [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4431-00-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-122575. |  |
| Aurintricarboxylic Acid | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase. Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis. Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM. Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ata. Product Category: Inhibitors. Appearance: Powder. CAS No. 4431-00-9. Molecular formula: C22H14O9. Mole weight: 422.34. Purity: 0.85. Canonical SMILES: C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)O)C(=O)O)C(=O)O)O. Product ID: ACM4431009. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Aurintricarboxylic acid ammonium salt | Aurintricarboxylic acid ammonium salt (CAS# 569-58-4) is used in preparation method of amorphous silica-alumina catalyst for use in reaction of methanol and ammonia to produce monomethylamine, dimethylamine and trimethylamine. Synonyms: azane;5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid. CAS No. 569-58-4. Molecular formula: C22H23N3O9. Mole weight: 473.43. | |
| Aurintricarboxylic acid ammonium salt (Aluminon) | 100g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C22H23N3O9. CAS No. 569-58-4. Prepack ID 28596801-100g. Molecular Weight 473.43. See USA prepack pricing. |  |
| Auristatin E | Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Synonyms: Auristatin E. Grades: ≥96.0% (HPLC). CAS No. 160800-57-7. Molecular formula: C40H69N5O7. Mole weight: 732.01. | |
| Auristatin E | Auristatin E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 160800-57-7. Molecular Formula: C40H69N5O7. Mole Weight: 732.02. Catalog: APB160800577. |  |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| Auristatin F | Auristatin F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 163768-50-1. Molecular Formula: C40H67N5O8. Mole Weight: 746. Catalog: APB163768501. | |
| Auristatin PE | Auristatin PE. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149606-27-9. Molecular Formula: C39H67N5O6. Mole Weight: 701.99. Catalog: APB149606279. | |
| Auristatin T | Auristatin T. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1799603-53-4. Molecular Formula: C35H65N5O9. Mole Weight: 699.92. Catalog: APB1799603534. | |
| Aurodox | It is produced by the strain of Streptomyces goldiniensis var. goldiniensis. Aurodox is a polyketide antibiotic originally isolated from S. goldiniensis, which inhibits bacterial protein biosynthesis by interrupting the functional cycle of Elongation Factor-Tu (EF-Tu). Aurodox is a type 3 secretion system (T3SS) inhibitor and growth promotor in poultry. It is active against Gram-positive bacteria, including B. megaterium, B. anthracis, and M. hominis (MICs = 0.06, 0.6, and 3-10 μg/ml, respectively). Synonyms: Antibiotic X 5108; Goldinodox; Goldinomycin; 1-methyl-Mocimycin; Benzamide; CYT11387. Grades: ≥95%. CAS No. 12704-90-4. Molecular formula: C44H62N2O12. Mole weight: 810.97. | |
| Aurodox (1-Methylmocimycin, Antibiotic X 5108, Goldinodox, Goldinomycin, NSC 233989) | Antibiotic. Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu). Type 3 secretion system (T3SS) inhibitor. Growth promotor in poultry. Group: Biochemicals. Grades: Highly Purified. CAS No. 12704-90-4. Pack Sizes: 1mg, 2.5mg. US Biological Life Sciences. |  Worldwide |
| Aurodox (1-Methylmocimycin, Antibiotic X 5108, Goldinodox, Goldinomycin, NSC 233989, Benzamide, CYT11387) | Isolated from Streptomyces sp. K06-0806. Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu). Effective against streptococcus pyogenes infections. It may promote growth in poultry. Group: Biochemicals. Grades: Highly Purified. CAS No. 12704-90-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aurofusarin | Dimeric naphthoquinone. Antibiotic activity. Mycotoxin. Toxic against mammalians and avian species. Analytical standard in food industry. Group: Biochemicals. Alternative Names: 4H-Naphtho[2,3-b]pyran, bimol. deriv.; 5,5-Dihydroxy-8,8-dimethoxy-2,2-dimethyl[7,7-bi-4H-naphtho[2,3-b]pyran]-4,4,6,6,9,9-hexone; Aurofusarin; NSC 244432. Grades: Highly Purified. CAS No. 13191-64-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aurofusarin | Aurofusarin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aurofusarin, (7,7-Bi-4H-naphtho(2,3-b)pyran)-4,4,6,6,9,9-hexone, 5,5-dihydroxy-8,8-dimethoxy-2,2-dimethyl-, 13191-64-5, Airofusorin, AC1Q6OJ7, SureCN5578918, KST-1A1369, AC1L4100, AR-1A7077, NSC244432, NSC-244432, A807820, 5-hydroxy-7-(5-hydroxy-8-methoxy-2-methyl-4,6,9-trioxo-7-benzo[g][1]benzopyranyl)-8-methoxy-2-methylbenzo[g][1]benzopyran-4,6,9-trione, 5-hydroxy-7-(5-hydroxy-8-methoxy-2-methyl-4,6,9-trioxobenzo[g]chromen-7-yl)-8-methoxy-2-methylbenzo[g]chromene-4,6,9-trione, 8-methoxy-7-[8-methoxy-2-methyl-5-oxidanyl-4,6,9-tris(oxidanylidene)benzo[g]chromen-7-yl]-2-methyl-5-oxidanyl-benzo[g]chromene-4,6,9-trione. Product Category: Heterocyclic Organic Compound. CAS No. 13191-64-5. Molecular formula: C30H18O12. Mole weight: 570.456720 [g/mol]. Purity: 0.96. IUPACName: 5-hydroxy-7-(5-hydroxy-8-methoxy-2-methyl-4,6,9-trioxobenzo[g]chromen-7-yl)-8-methoxy-2-methylbenzo[g]chromene-4,6,9-trione. Density: 1.69g/cm³. Product ID: ACM13191645. Alfa Chemistry ISO 9001:2015 Certified. | |
| Auroglaucin | It is produced by the strain of Aspergillus spp. Synonyms: 2-[(1E,3E,5E)-1,3,5-Heptatrienyl]-3,6-dihydroxy-5-(3-methyl-2-butenyl)benzaldehyde; Auroglaucine; 2-((1E,3E,5E)-hepta-1,3,5-trien-1-yl)-3,6-dihydroxy-5-(3-methylbut-2-en-1-yl)benzaldehyde. CAS No. 41451-81-4. Molecular formula: C19H22O3. Mole weight: 298.38. | |
| Aurora 17729 | Aurora 17729. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AURORA 17729. Product Category: Heterocyclic Organic Compound. CAS No. 71082-34-3. Molecular formula: C13H13NO4. Mole weight: 247.25. Product ID: ACM71082343. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ethyl 4-hydroxy-8-methoxyquinoline-3-carboxylate, Aurora (1779 ship). | |
| AURORA 19959 | AURORA 19959. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AURORA 19959;OTAVA-BB BB7014740329;3-CHLORO-7-HYDROXY-4H-CHROMEN-4-ONE;OTAVA-BB 7014740329. Product Category: Heterocyclic Organic Compound. CAS No. 685848-25-3. Molecular formula: C9H5ClO3. Mole weight: 196.59. Product ID: ACM685848253. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aurora 2035 | Aurora 2035. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Maybridge1_002371, DivK1c_001123, HMS548D17, ISWHPQMMRBTZOY-UHFFFAOYSA-, MolPort-000-419-158, MolPort-000-754-331, MolPort-003-912-933, NSC228504, CID313644, ZINC03850598, CDS1_000083, BAS 00405087, AB00123098-02, 5-(3,4-Dimethoxy-benzylidene)-pyrimidine-2,4,6-trione, A2823/0119215, 66386-22-9, InChI=1/C13H12N2O5/c1-19-9-4-3-7(6-10(9)20-2)5-8-11(16)14-13(18)15-12(8)17/h3-6H,1-2H3,(H2,14,15,16,17,18). Product Category: Heterocyclic Organic Compound. CAS No. 66386-22-9. Molecular formula: C13H12N2O5. Mole weight: 276.2448. Purity: 0.96. IUPACName: 5-[(3,4-dimethoxyphenyl)methylidene]-1,3-diazinane-2,4,6-trione. Canonical SMILES: COC1=C(C=C(C=C1)C=C2C(=O)NC(=O)NC2=O)OC. Product ID: ACM66386229. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aurora 3, Control peptide (STK13, Serine Threonine Kinase 13, Aurora C, AIE2, AIK3, Aurora Related Kinase 3, Aurora/IPL1-like) | A synthetic peptide derived from the N-terminus of the human Aurora-3 protein. Group: Molecular Biology. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Aurora 6910 | Aurora 6910. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(3,4,5-Trimethoxy-benzoyl)-4-chlor-anilin; 3.4.5-Trimethoxy-benzoesaeure-<4- | |
| Aurora A Inhibitor I | Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM. It is 1000-fold more selective for Aurora A than Aurora B. Synonyms: TC-S 7010; TC S 7010; TCS7010. Grades: >98%. CAS No. 1158838-45-9. Molecular formula: C31H31ClFN7O2. Mole weight: 588.07. | |
| Aurora A inhibitor II | Aurora A inhibitor II is a potent and selective inhibitor of Aurora A kinase (AurA; IC50 = 4.3 nM). Synonyms: 4-[[2-[[4-[2-(4-acetyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-N-(2-chlorophenyl)-Benzamide. Grades: 99%. CAS No. 1158838-43-7. Molecular formula: C31H29ClFN7O3. Mole weight: 602.06. | |
| Aurora Kinase A active human, Recombinant | Aurora A kinase also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora A is activated by one or more phosphorylations and its activity peaks during the G2 phase to M phase transition in the cell cycle. Human aurora kinase a (genbank accession no. nm_003600), amino acids 2-403 with n-terminal his6-tag, mw=50 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: Aurora Kinase A; Aurora A kinase; serine/threonine-protein kinase 6; AURKA; AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7. Purity: > 90% (SDS-PAGE). ARK1. Mole weight: mol wt 50 kDa. Activity: ~17,000 units/mg protein. Form: aqueous solution. Source: baculovirus infected Sf9 cells. Species: Human. Aurora Kinase A; Aurora A kinase; serine/threonine-protein kinase 6; AURKA; AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7. Pack: Minimum 50 ng protein/vial by Bradford. Cat No: NATE-0087. |  |
| Aurora kinase inhibitor-2 | Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC 50 s of 310 nM and 240 nM for Aurora A and Aurora B , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331770-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112355. | |
| Aurora Kinase Inhibitor II | The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A with IC50 of 0.39 μM. This compound has the ability to permeate the cell and is involved in the regulation of the cell cycle, particularly cell division. This compound has the ability to permeate the cell and is involved in the regulation of the cell cycle, particularly cell division. Synonyms: 4-(4?-Benzamidoanilino)-6,7-dimethoxyquinazoline. Grades: ≥98%. CAS No. 331770-21-9. Molecular formula: C23H20N4O3. Mole weight: 400.4. | |
| Aurora Kinase Inhibitor III | Aurora kinase inhibitor III is a potent ATP-competitive aurora related kinase inhibitor with IC50 of 42 nM. Aurora kinase inhibitor III is a cell-permeable, 2,4-dianilinopyrimidine compound which has been used to study a variety of tumor types. It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively). Aurora kinase protein levels are elevated in c-myc-driven B-cell lymphomas in both mice and humans. Study of the inhibition of Aurora kinase proteins could lead to potential treatments for malignancies. Synonyms: Aurora Kinase Inhibitor III; AKI-7169; AKI 7169; AKI7169. Grades: ≥98%. CAS No. 879127-16-9. Molecular formula: C21H18F3N5O. Mole weight: 413.4. | |
| Aurora Kinase Inhibitor VI, ZM447439 (4-(4-(N-Benzoylamino)anilino)-6- methoxy-7- (3- (1-morpholino) propoxy) quinazoline) | A cell-permeable quinazoline compound that targets the ATP binding pocket and an adjacent cleft and acts as a potent and reversible inhibitor of Aurora A and Aurora B (IC50=110 and 130nM, respectively) with moderate to excellent selectivity among closely related 16-kinase panel (IC50=0.88, 1.03 and 1.79uM for Lck, Src and MEK1, respectively, and IC50>10uM for Cdk1/2/4, Plk1, Chk1). Blocks phosphorylation of Histone H3-Ser10 in Xenopus cycling egg extracts at 20uM, and reduces mitotic spindle assembly. Shown to repress kinetochore localization of BubR1, Cenp-E, and Mad2, and arrest the growth of proliferating tumor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 331771-20-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aurothioglucose | Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC 50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gold thioglucose. CAS No. 12192-57-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-A0068. | |
| Aurothioglucose | Aurothioglucose is used in the treatment of rheumatoid arthritis and psoriasis. Synonyms: Aurothioglucose; Solganal; SKF 10056; SKF-10056; SKF10056; gold thioglucose; Aurothioglucose hydrate. Grades: >98%. CAS No. 12192-57-3. Molecular formula: C6H11AuO5S. Mole weight: 392.18. | |
| Aurothioglucose USP | (a-D-glucopyranosylthio)gold. Grades: USP. CAS No. 12192-57-3. Product ID: 8-01219. Molecular formula: C6H11AuO5S. Mole weight: 392.18. Properties: low Pd, low hydroxyl value. |  |
| Aurothiomalate sodium | Aurothiomalate sodium is a potent and selective oncogenic PKC Ι signaling inhibitor. Aurothiomalate sodium inhibits tumor cell proliferation and not cell apoptosis. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium, an anti-rheumatoid agent, exhibits potent anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 12244-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106381. | |
| Australian Chemical Suppliers | Australian Chemical Suppliers Database | Australian Chemical Suppliers Australia |
| Australifungin | Australifungin is produced by the strain of Sporormiella australis. As an inhibitor of Shinganine n-acyl-transferase, it has strong antifungal activity, with MIC of 0.015-0.5 μg/mL for candida, cryptococcus neoforme, saccharomyces cerescens and other fungi, and 0.125 ~ 1μg/ mL for aspergillus. Australian fennetol has a low antifungal effect. Molecular formula: C23H36O6. Mole weight: 408.53. | |
| Australine hydrochloride | Australine hydrochloride is a polyhydroxylated pyrrolizidine alkaloid that inhibits a-glucosidase, amyloglucosidase, and glucosidase I. Synonyms: 1H-Pyrrolizine-1,2,7-triol, hexahydro-3-(hydroxymethyl)-, (1R,2R,3R,7S,7aR)-, hydrochloride (1:1); (+)-Australine hydrochloride; (1R,2R,3R,7S,7aR)-3-(Hydroxymethyl)hexahydro-1H-pyrrolizine-1,2,7-triol hydrochloride (1:1). Grades: ≥95%. CAS No. 186766-07-4. Molecular formula: C8H15NO4.HCl. Mole weight: 225.67. | |
| Au TiO2 Core Shell Nanoparticles | Au TiO2 Core Shell Nanoparticles. Group: Core shell nanoparticles. 99.9%. |  |
| Au TiO2 Core-Shell Nanoparticles | Au TiO2 Core-Shell Nanoparticles. Group: Core shell nanoparticles. 99.9%. | |
| Autocamtide 2 | Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II ( CaMKII ). It can be used in the CaMKII activity assay. Uses: Scientific research. Group: Peptides. Alternative Names: Autocamtide II. CAS No. 129198-88-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0225. | |
| Autocamtide 2 | Autocamtide 2 is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: Autocamtide II; H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine. Grades: ≥95%. CAS No. 129198-88-5. Molecular formula: C65H118N22O20. Mole weight: 1527.77. | |
| Autocamtide 2, amide | Autocamtide 2, amide is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-NH2. Grades: ≥95%. Molecular formula: C65H119N23O19. Mole weight: 1526.79. | |
| Autocamtide-2-related inhibitory peptide | Autocamtide-2-related inhibitory peptide. Group: Biochemicals. Grades: Purified. CAS No. 167114-91-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Autocamtide-2-Related Inhibitory Peptide | Autocamtide-2-related inhibitory peptide is a highly selective, specific and potent inhibitor of calmodulin-dependent protein kinase II (CaM kinase II) with I50 value of 40 nM. It is selective over PKC, PKA and CaM kinase IV. Synonyms: AIP; [Ala9]-Autocamtide 2. Grades: ≥97% by HPLC. CAS No. 167114-91-2. Molecular formula: C64H116N22O19. Mole weight: 1497.74. | |
| Autocamtide-2-related inhibitory peptide, myristoylated | Autocamtide-2-related inhibitory peptide, myristoylated is a CaM kinase II inhibitor. It is an enhanced cell-permeable derivative of autocamtide-2-related inhibitory peptide. It blocks reinstatement of morphine-seeking behavior in vivo by pretreatment. Synonyms: AIP Myristoylated; Myr-AIP. Grades: >98%. CAS No. 201422-04-0. Molecular formula: C78H142N22O20. Mole weight: 1708.12. | |
| Autocamtide-2-related inhibitory peptide, myristoylated acetate | Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor that blocks the reinstatement of morphine-seeking behavior in vivo by pretreatment. It is an enhanced cell-permeable derivative of autocamtide-2-related inhibitory peptide. Synonyms: AIP Myristoylated acetate; Myr-AIP acetate; N2-(1-Oxotetradecyl)-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-alanyl-L-leucine acetate; m-AIP acetate; Myristoylated autocamtide-2-related inhibitory peptide acetate; H-Lys(myristoyl)-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C80H146N22O22. Mole weight: 1768.15. | |
| Autocamtide-2-related inhibitory peptide TFA | Autocamtide-2-related inhibitory peptide TFA is a highly selective, specific and potent inhibitor of calmodulin-dependent protein kinase II (CaM kinase II). Synonyms: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH.TFA; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine trifluoroacetic acid; Autocamtide-2-Related Inhibitory Peptide Trifluoroacetate; CaM kinase II inhibitor TFA salt. Grades: ≥98%. Molecular formula: C64H116N22O19.C2HF3O2. Mole weight: 1611.76. | |
| Autocamtide 2 TFA | Autocamtide 2 TFA is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH.TFA; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine trifluoroacetic acid; Autocamtide 2 trifluoroacetate salt. Grades: ≥95%. Molecular formula: C67H119F3N22O22. Mole weight: 1641.79. | |
| autoinducer-2 kinase | The enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2. Group: Enzymes. Synonyms: lsrK (gene name). Enzyme Commission Number: EC 2.7.1.189. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3021; autoinducer-2 kinase; EC 2.7.1.189; lsrK (gene name). Cat No: EXWM-3021. | |
| Autoinducing Peptide I | Autoinducing Peptide I is an autoinducing peptide (AIP) that activates the agr (accessory gene regulator) site to control the expression of extracellular proteins in S. aureus. Synonyms: AIP1; H-Tyr-Ser-Thr-cyclo(-Cys-Asp-Phe-Ile-Met); L-Methionine, L-tyrosyl-L-seryl-L-threonyl-L-cysteinyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-, (8?4)-thiolactone; L-Tyrosyl-L-seryl-N-{(3S,6S,9S,12S,15R)-9-benzyl-6-[(2S)-2-butanyl]-12-(carboxymethyl)-3-[2-(methylsulfanyl)ethyl]-2,5,8,11,14-pentaoxo-1-thia-4,7,10,13-tetraazacyclohexadecan-15-yl}-L-threoninamide. Grades: ≥95%. CAS No. 200010-29-3. Molecular formula: C43H60N8O13S2. Mole weight: 961.11. | |
| Automatic fusion machine for XRF | Automatic fusion machine for XRF. Uses: For analytical and research use. Group: Equipment for sample preparation. Catalog: APS005934. Shipping: Room Temperature. | |
| Autophagy Compound Library | A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3200. Categories: Autophagy Compounds Libraries. |  |
| Autophagy inducer 7 | Autophagy inducer 7 (Compound SSA) is an Autophagy and Apoptosis inducer. Autophagy inducer 7 activates autophagy by inhibiting Akt/mTOR signaling and the expression of downstream proteins. Autophagy inducer 7 suppresses DNA synthesis and causes a G0-G1 cell-cycle arrest. Autophagy inducer 7 inhibits tumor cell growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 944159-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171047. | |
| Autophagy Inhibitor IV, Cpd18 (3-methyl-6-(3-methylpiperidin-1-yl)-3H-purine, 3-MA analog, Cpd 18) | A cell-permeable 3-methyladenine (3-MA) derivative that acts as an autophagy inhibitor via the inhibition of class III PI3K, and without touching class I PI3K. Shown to block 80% of starvation-induced autophagy at 1 mM (IC50 = 0.67mM, compared with 3-MA at 6 mM). Displays much better solubility than 3-MA (5 times more soluble in water and 30 times more soluble in DMSO). Also found to reduce cell viability by 55% at 1 mM at 12 hours compared with 72% reduction for 3-MA at 10mM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Autophinib | Autophinib is a novel potent autophagy inhibitor, which can inhibit autophagy induced by starvation or rapamycin with IC50 values of 0.04 μM and 0.09 μM, respectively. Synonyms: 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine. CAS No. 1644443-47-9. Molecular formula: C14H11ClN6O3. Mole weight: 346.73. | |
| Autotaxin Inhibitor III, PF-8380 (Atx Inhibitor III, PF-8380, 6-(3-(Piperazin-1-yl)propanoyl)-benzo[d]oxazol-2(3H)-one) | An orally bioavailable piperazinyl benzoxazolone compound that acts as a substrate competitive and tight-binding inhibitor of autotaxin activity {IC50=2.8 and 1.7nM for recombinant human enzyme-b isoform employing FS-3 and LPC (lysophosphatidyl choline) as substrates, respectively; 1.16 and 1.15nM for rat/murine enzyme-FS-3 and fetal fibroblast cell-LPC; 101nM for human whole blood}. Displays desirable pharmacokinetics properties and efficiently blocks inflammation-induced LPA (lysophosphatidic acid) production both in plasma and at the site of inflammation by 95% in rat adjuvant-induced arthritis model (30mg/kg, p.o.).CAS No:1144035-53-9. Group: Biochemicals. Grades: Highly Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| AUY954 | NVP-AUY954 is an orally-available, benzothiazole-based, monoselective agonist of the sphingosine-1-phosphate receptor 1 (S1P1) intended for the treatment of human autoimmune mediated inflammatory neuropathies. NVP-AUY954 efficacy has been correlated with an accumulation of plasmacytoid dendritic cells (pDC), which may have therapeutic value in the treatment of multiple sclerosis. Uses: Sphingosine 1 phosphate receptor modulators. Synonyms: AUY954; AUY-954 free base; 820240-77-5; CHEMBL4579553; 820240-77-5 (free base); 3-[[2-[4-phenyl-3-(trifluoromethyl)phenyl]-1-benzothiophen-5-yl]methylamino]propanoic acid; 3-(((2-(2-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)benzo[b]thiophen-5-yl)methyl)amino)propanoic acid; N-[[2-[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]benzo[b]thien-5-yl]methyl]-beta-alanine; AUY 954; GTPL2925; SCHEMBL2237377; BCP33492; BDBM50507187; AKOS040750638; NVP-AUY954; AUY-954; AUY 954; Q27074628; 3-{[2-(2-trifluoromethyl-biphenyl-4-yl)benzo[b]thiophen-5-ylmethyl]amino}propionic acid. Grades: ≥98%. CAS No. 820240-77-5. Molecular formula: C25H20F3NO2S. Mole weight: 455.5. | |
| AV023 | AV023 is a potent inhibitor of ANKRD22. AV023 promotes the expansion of gastrointestinal mucosal epithelial stem cells and indirectly activates the Wnt classical pathway, which helps the recovery of damaged gastrointestinal mucosal tissues in the body (extracted from patent CN111205231B) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1107710-62-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145686. | |
| AV123 | AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor ( IC 50 =12.12 μM). AV123 blocks the TNF-α-induced necroptotic ( EC 50 =1.7 μM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 233605-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151369. | |
| AV-412 | AV-412 is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may suppress tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization. Synonyms: AV 412; AV412; N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide. CAS No. 451492-95-8. Molecular formula: C27H28ClFN6O. Mole weight: 507.01. | |
| AV-412 Tosylate | AV-412 is a dual EGFR/ErbB2 kinase inhibitor. It completely inhibits the tumor growth of both H1650 and H1975 xenografts in nude mice. It is proved that AV-412 suppresses tumor growth via the inhibition of EGFR. Besides that, AV-412 also shows antitumor effects against various tumor models expressing EGFR, ErbB2 or both receptors, such as breast cancer KPL-4, prostate cancer DU145 and lung cancer LC-376. Uses: Antineoplastic agents. Synonyms: N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide bis(4-methylbenzenesulfonate); MP-412; MP 412; MP412; AV-412; AV 412; AV412; AV-412 tosylate. Grades: >98%. CAS No. 451493-31-5. Molecular formula: C41H44ClFN6O7S2. Mole weight: 851.41. | |
| AV5124 | AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417851-93-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164927. | |
| Avacopan | Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor ( C5aR ) inhibitor with an IC 50 of 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCX168. CAS No. 1346623-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17627. | |
| Avadomide | Avadomide is an orally active cereblon modulator. Avadomide modulates cereblon E3 ligase activity, inhibits NF-κB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide exhibits potent antitumor and immunomodulatory activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC 122. CAS No. 1015474-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100507. | |
| Avagacestat | Avagacestat (BMS-708163) is a potent inhibitor of γ-secretase , with IC 50 s of 0.27 nM and 0.30 nM for Aβ42 and Aβ40 inhibition; Avagacestat (BMS-708163) also inhibits NICD (Notch IntraCellular Domain) with IC 50 of 0.84 nM and shows weak inhibition of CYP2C19, with IC 50 of 20 μM. Avagacestat can be used for Alzheimer disease research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-708163. CAS No. 1146699-66-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50845. | |
| Avagacestat | BMS-708163 is a potent and orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP (IC50 = 0.30 nM) to Aβ40 than signaling through Notch (IC50s = 58 nM). Uses: Gamma secretase inhibitors and modulators. Synonyms: Avagacestat; BMS 708163; (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. Grades: >98%. CAS No. 1146699-66-2. Molecular formula: C20H17ClF4N4O4S. Mole weight: 520.89. | |
| Avanafil | A phosphodiesterase. Group: Biochemicals. Alternative Names: (S) -2- (2-Hydroxymethyl-1-pyrrolidinyl) -4- (3-chloro-4-methoxybenzylamino) -5-[ (2-pyrimidinylmethyl) carbamoyl]pyrimidine; 4-[[ (3-Chloro-4-methoxyphenyl) methyl]amino]-2-[ (2S) -2- (hydroxymethyl) -1-pyrrolidinyl]-N- (2-pyrimidinylmethyl) -5-pyrimidinecarboxamide; TA 1790. Grades: Highly Purified. CAS No. 330784-47-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avanafil | Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC 50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: TA1790. CAS No. 330784-47-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-18252. | |
| Avanafil Dichloride Impurity | Avanafil Dichloride Impurity. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H25Cl2N7O3. Mole Weight: 518.4. Catalog: APB06512. | |
| Avanafil Impurity 1 | Avanafil Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3,5-dichloro-4-methoxyphenyl)methanamine. Molecular Formula: C8H9Cl2NO. Mole Weight: 206.07. Catalog: APB02660. | |
| Avanafil Impurity 1 | Avanafil Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 372117-54-9. Molecular Formula: C18H22ClN5O3. Mole Weight: 391.86. Catalog: APB372117549. | |
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