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| Product | Description | |
|---|---|---|
| BVT-14225 | BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50 = 52 nM), which is 1,000 fold lower than that for 11β-HSD2. Synonyms: 2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide; BVT-14225; BVT 14225; BVT14225. CAS No. 376638-65-2. Molecular formula: C16H20ClN3O3S2. Mole weight: 401.93. |  |
| BVT 2733 | BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Synonyms: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grades: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95. | |
| BVT 2733 hydrochloride | BVT 2733 hydrochloride is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1. Synonyms: BVT 2733 hydrochloride; BVT2733 hydrochloride; BVT-2733 hydrochloride; 3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide hydrochloride. Grades: 99%. CAS No. 376641-65-5. Molecular formula: C17H21ClN4O3S2.HCl. Mole weight: 465.42. | |
| BVT 948 | BVT 948. Group: Biochemicals. Grades: Purified. CAS No. 39674-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BVT-948 | BVT 948 is a non-competitive and cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM). BVT 948 displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP, and enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Some cytochrome P450 isoforms are also suppressed by BVT 948 (IC50 <10 μM). Synonyms: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione. Grades: ≥98% by HPLC. CAS No. 39674-97-0. Molecular formula: C14H11NO3. Mole weight: 241.24. | |
| Bw 175 | Heterocyclic Organic Compound. CAS No. 120716-81-6. Catalog: ACM120716816. |  |
| BW 245C | BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1) agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM and has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation. Synonyms: 7-[(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl]heptanoic acid; 245C77; 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin; BW 245C; BW 245C, (R*,S*)-(+-); BW-245C. CAS No. 72814-32-5. Molecular formula: C19H32N2O5. Mole weight: 368.47. | |
| BW 246C | The prostaglandin D2 (PGD2) receptors are the members of G protein-coupled receptors. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). BW 246C is a DP receptor agonist. BW 246C is the less active C-8 diastereomer of the DP receptor agonist BW 245C. The activity of BW 245C is 70-fold greater than that of BW 246C. Synonyms: 8-epi BW 245C. Grades: ≥98%. CAS No. 65705-83-1. Molecular formula: C19H32N2O5. Mole weight: 368.5. | |
| BW 373U86 | BW 373U86 is a potent and selective non-peptide δ-opioid receptor agonist (Ki = 1.8, 15 and 34 nM for δ, μ and κ receptors, respectively). Synonyms: BW-373U86; SNC-86; BW 373U86; SNC 86; BW373U86; SNC86; 4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide. Grades: ≥99% by HPLC. CAS No. 155836-50-3. Molecular formula: C27H37N3O2. Mole weight: 435.61. | |
| BW-723C86 | BW-723C86 is an orally active and a selective 5-HT 2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369. |  |
| BW 723C86 hydrochloride | BW 723C86 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 160521-72-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BW 723C86 hydrochloride | BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist used for the treatment of certain CNS disorders, such as epilepsy, migraine and feeding disorders. Uses: The treatment of cns disorders as epilepsy, migraine and feeding disorders. Synonyms: BW723C86; BW-723-C-86; BW 723 C 86; BW-723C86; BW 723C86; α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 160521-72-2. Molecular formula: C16H18N2OS.HCl. Mole weight: 322.85. | |
| BW 755C | Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grades: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20. | |
| Bw-a 4c | Heterocyclic Organic Compound. CAS No. 106328-57-8. Molecular formula: C17H17N1O3. Mole weight: 283.32. Catalog: ACM106328578. | |
| BW-A78U | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. It is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release. Synonyms: BW A78U. Grades: ≥98%. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27. | |
| BW-A 78U | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. Group: Fluorinated apis. Alternative Names: 9-(2-fluorobenzyl)-6-(methylamino)-9H-purine. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 9-[(2-fluorophenyl)methyl]-N-methylpurin-6-amine. Catalog: OFC101155026. | |
| Bw a868c | Heterocyclic Organic Compound. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.58. Catalog: ACM118675506. | |
| BW A868C | Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grades: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6. | |
| BW-B 70C | BW-B 70C. Group: Biochemicals. Grades: Purified. CAS No. 134470-38-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BW-B 70C | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
| BWX 46 | BWX 46. Group: Biochemicals. Grades: Purified. CAS No. 172997-92-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BX-320 | BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC 50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702676-93-5. Pack Sizes: 1 mg. Product ID: HY-10515. | |
| BX341 | BX341, also known as bifluranol, is a new fluorinated bibenzyl anti-androgen and one of a series of bibenzyls designed to present some of the hormonal properties of diethylstilboestrol (DES) but with a lower potential for toxicity. Synonyms: BX341; BX 341; BX-341; 2-fluoro-4-[3-(3-fluoro-4-hydroxyphenyl)pentan-2-yl]phenol; bifluranol; erythro-2,3-bis(3-fluor-4-hydroxyphenyl)pentan. CAS No. 34633-34-6. Molecular formula: C17H18F2O2. Mole weight: 292.32. | |
| BX 430 | BX 430 is a selective P2X4 allosteric antagonist (IC50 = 0.54 μM) binding noncompetitively to extracellular allosteric site. It exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. BX 430 is inactive at mouse and rat P2X4 receptors. Synonyms: BX430; BX-430; BX 430; N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea. Grades: ≥99% by HPLC. CAS No. 688309-70-8. Molecular formula: C15H15Br2N3O. Mole weight: 413.11. | |
| BX 471 | BX 471 is a selective CCR1 antagonist. Synonyms: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea; BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. | |
| BX 471 | BX 471. Group: Biochemicals. Grades: Purified. CAS No. 217645-70-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-471 | BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 was developed Berlex and its parent company, Schering AG. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS). In March 2000, BX-471 was undergoing phase I trials for the potential treatment of autoimmune diseases. Group: Antagonists. Alternative Names: BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea. Canonical SMILES: C[C@H]1N (C (COC2=CC=C (Cl)C=C2NC (N)=O)=O)CCN (CC3=CC=C (F)C=C3)C1. Catalog: ACM217645700. | |
| BX471 hydrochloride | BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). Synonyms: BX-471 hydrochloride; BX 471 hydrochloride; (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea hydrochloride. CAS No. 288262-96-4. Molecular formula: C21H25Cl2FN4O3. Mole weight: 471.35. | |
| BX471 (N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-urea, ZK-811752) | An orally active, selective antagonist for chemokine receptor 1 (CCR-1) (Ki = 1-5nM). Has been used in studies related to intracellular calcium mobilization and migration of leukocytes mediated through CCR-1. Group: Biochemicals. Grades: Highly Purified. CAS No. 217645-70-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BX 513 hydrochloride | BX 513 hydrochloride is a selective CCR1 receptor antagonist (Ki = 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors, respectively), and also acts as a US28 agonist. It inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Synonyms: BX-513 hydrochloride; BX513 hydrochloride; 1-Piperidinepentanenitrile, 4-(4-chlorophenyl)-4-hydroxy-α,α-diphenyl-, hydrochloride (1:1); 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride; VUF 2274 hydrochloride; 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile hydrochloride. Grades: ≥99% by HPLC. CAS No. 1216540-18-9. Molecular formula: C28H29ClN2O.HCl. Mole weight: 481.46. | |
| BX 513 hydrochloride | BX 513 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216540-18-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-517 | BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM). Synonyms: (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidic acid; BX-517; BX 517; BX517; PDK1 inhibitor2. CAS No. 850717-64-5. Molecular formula: C15H14N4O2. Mole weight: 282.3. | |
| BX795 | BX795 Inhibitor. Uses: Scientific use. Product Category: T1830. CAS No. 702675-74-9. |  |
| BX 795 | BX 795. Group: Biochemicals. Grades: Purified. CAS No. 702675-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-795 | 3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Synonyms: BX 795; BX795. Grades: ≥98%. CAS No. 702675-74-9. Molecular formula: C23H26IN7O2S. Mole weight: 591.47. | |
| BX912 | BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc. Synonyms: BX912; BX 912; BX-912. Grades: 0.98. CAS No. 702674-56-4. Molecular formula: C20H23BrN8O. Mole weight: 471.363. | |
| BXL 628 | BXL 628 is a vitamin D3 analogue that competes with vitamin D receptor (VDR) for inhibition of prostate cell growth and RhoA/Rho-kinase signaling, a calcium sensitizing pathway. BXL 628 exhibits anti-proliferative and anti-inflammatory properties in benign prostatic hyperplasia (BPH) treatment. Uses: Potential treatment of benign prostatic hyperplasia (bph). Synonyms: Elocalcitol; (1R,3Z,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol. Grades: 99%. CAS No. 199798-84-0. Molecular formula: C29H43FO2. Mole weight: 442.65. | |
| BxPC-3 Transfection Reagent | Transfection Reagent for BxPC3 Pancreatic Cancer Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6321. |  Nevada, Texas, USA |
| Byakangelicin | Byakangelicin. Group: Biochemicals. Grades: Plant Grade. CAS No. 482-25-7. Pack Sizes: 20mg. Molecular Formula: C17H18O7, Molecular Weight: 334.32. US Biological Life Sciences. | Worldwide |
| Byakangelicol | Byakangelicol. Group: Biochemicals. CAS No. 26091-79-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Byakangelicol | Byakangelicol is a furanocoumarin derivative which shows inhibitory effects against P-glycoprotein at the blood-brain barrier. It acts as an anti-proliferative agent causing G2/M arrest in melanoma cells. Synonyms: (R)-(+)-9-(2,3-Epoxy-3-methylbutoxy)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one. Grades: >98%. CAS No. 26091-79-2. Molecular formula: C17H16O6. Mole weight: 316.3. | |
| b,y-Carotene,3',4'-didehydro-2'-[(6-deoxy-a-L-mannopyranosyl)oxy]-1',2'-dihydro-1',3-dihydroxy-,(3s,3'e)- | Heterocyclic Organic Compound. Alternative Names: MYXOXANTHOPHYLL;3',4'-Didehydro-2'-[(6-deoxy-α-L-mannopyranosyl)oxy]-1',2'-dihydro-1',3-dihydroxy-β,ψ-carotene. CAS No. 11004-68-5. Molecular formula: C46H66O7. Mole weight: 731.01. Catalog: ACM11004685. | |
| BYK 191023 dihydrochloride | BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216722-25-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107584. | |
| BYK 191023 dihydrochloride | BYK 191023 dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS) (IC50 = 86, 17000, 162000 nM for iNOS, nNOS and eNOS, respectively) acting in a NADPH- and time-dependent manner. BYK 191023 decreases the nitrite levels in rats, and reverses pathological hypotension in the rodent endotoxin model. Synonyms: BYK191023 Dihydrochloride; BYK-191023 Dihydrochloride; BYK 191023 Dihydrochloride; BYK191023 2HCl; BYK-191023 2HCl; BYK 191023 2HCl;; 2-[2-(4-Methoxy-2-pyridinyl)ethyl]-1H-imidazo[4,5-b]pyridine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1216722-25-6. Molecular formula: C14H14N4O.2HCl. Mole weight: 327.21. | |
| BYK 191023 Dihydrochloride | BYK 191023 Dihydrochloride was used to study the compositions of pentosan polysulfate salts for oral administration and methods of use. Group: Biochemicals. Grades: Highly Purified. CAS No. 1216722-25-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H14N4O; 2(HCl), Molecular Weight: 254.2923646. US Biological Life Sciences. | Worldwide |
| BYK 204165 | BYK 204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 = 5.38 and 7.35 for PARP-2 and PARP-1, respectively). BYK 204165 is 100-fold more potent for PARP-1 than PARP-2. Synonyms: PARP Inhibitor XIV; BYK204165; BYK-204165; BYK 204165; RT-017290; RT017290; RT 017290. 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione. Grades: ≥99% by HPLC. CAS No. 1104546-89-5. Molecular formula: C15H12N2O2. Mole weight: 252.27. | |
| BYK 204165 | BYK 204165. Group: Biochemicals. Grades: Purified. CAS No. 1104546-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BYK 49187 | BYK 49187. Group: Biochemicals. Grades: Purified. CAS No. 163120-31-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BYK 49187 | BYK 49187 is a non-selective PARP inhibitor (pIC50 = 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2, respectively). Synonyms: BYK 49187; BYK49187; BYK-49187; 4,5-Dihydro-2-[4-(4-methyl-1H-imidazol-4-yl)-1-piperidinyl]-6H-imidazo[4,5,1-ij]quinolin-6-one. Grades: ≥98% by HPLC. CAS No. 163120-31-8. Molecular formula: C19H21N5O. Mole weight: 335.4. | |
| Byssochlamic acid | Byssochlamic acid is a mycotoxin produced by Byssochlamys fulva (Paecilomyces variotII) and Bys. nivea. CAS No. 743-51-1. Molecular formula: C18H20O6. Mole weight: 332.35. | |
| Byssochlamysol | Byssochlamysol is a steroid antibiotic extracted from the mycelium of Byssochlamys nivea. It has the activity of inhibiting the growth of tumor cells MCF-7. Molecular formula: C32H50O7. Mole weight: 546.73. | |
| Bz 423 | Bz 423 is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BZ48. CAS No. 216691-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13108. | |
| Bz 423 | Bz 423 has been found to be an ATP synthase inhibitor and could suppress disease in lupus-prone mice at some extent. Uses: Immunologic factors. Synonyms: Bz-423; Bz 423; Bz423; 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one. Grades: ≥98% by HPLC. CAS No. 216691-95-1. Molecular formula: C27H21ClN2O2. Mole weight: 440.92. | |
| Bz-Arg-4-Abz-OH HCl | Synonyms: Nα-Benzoyl-L-arginine 4-carboxyanilide hydrochloride; Bz-Arg-4-Abz-OH Hydrochloride. Grades: ≥ 98% by TLC. Molecular formula: C20H23N5O4.HCl. Mole weight: 433.89. | |
| Bz-Arg-4-Abz-OH·HCl | Bz-Arg-4-Abz-OH·HCl. Group: Biochemicals. Alternative Names: Na-Benzoyl-L-arginine 4-carboxyanilide hydrochloride. Grades: Highly Purified. CAS No. 60833-82-1. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C20H23N5O4·HCl. US Biological Life Sciences. | Worldwide |
| Bz-Arg-4-Abz-OH·HCl | Synonyms: Na-Benzoyl-L-arginine 4-carboxyanilide hydrochloride. CAS No. 60833-82-1. Molecular formula: C20H23N5O4. Mole weight: 397.43. | |
| Bz-Arg-4-Abz-OH·HCl 98+% (TLC) | Bz-Arg-4-Abz-OH·HCl 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 60833-82-1(net). Pack Sizes: 100mg, 25mg. US Biological Life Sciences. | Worldwide |
| Bz-Arg-Gly-Phe-Phe-Leu-4MbetaNA | A substrate for cathepsin D. Synonyms: benzoyl-Arg-Gly-Phe-Phe-Leu-MNA; Bz-Arg-Gly-Phe-Phe-Leu-4-methoxy-beta-naphthylamide; Bz-RGFFL-MNA. CAS No. 99112-24-0. Molecular formula: C50H59N9O7. Mole weight: 898.06. | |
| Bz-Arg-Gly-Phe-Phe-Pro-4MβNA HCl | Synonyms: Bz-Arg-Gly-Phe-Phe-Pro-4MbNA HCl; Bz-RGFFP-MNA HCl. CAS No. 201928-98-5. Molecular formula: C49H56ClN9O7. Mole weight: 918.49. | |
| BzATP triethylammonium | BzATP triethylammonium Inhibitor. Uses: Scientific use. Product Category: TP2226. CAS No. 112898-15-4. | |
| BzATP triethylammonium salt | Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist. Prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 uM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 112898-15-4. Pack Sizes: 1mg. Molecular Formula: C24H24N5O15P3. C18H45N3, Molecular Weight: 1018.97. US Biological Life Sciences. | Worldwide |
| BzATP triethylammonium salt | The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5-10 fold greater potency than ATP with EC50 of 0.7 μM. It also exhibits partial agonist activity at P2X1 and P2Y1 receptors. BzATP can also be used as a photoaffinity probe to study adenine nucleotide binding to ATPases. Synonyms: BzATP; Benzoylbenzoic adenosine 5'-triphosphate. Grades: ≥95%. CAS No. 112898-15-4. Molecular formula: C30H39N6O15P3. Mole weight: 816.6. | |
| BzATP Triethylammonium Salt (2 (3) -O- (4-Benzoylbenzoyl) adenosine-5-triphosphate tri(triethylammonium) Salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 ,3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP) | A prototypic P2X7 purinergic receptor agonist that exhibits about 3-fold higher agonistic potency for induction of nucleotide channels than ATP (EC50 = 15uM vs 50uM). Serves as a photo-affinity analog of ATP. Its agonistic activity is significantly reduced in the presence of serum albumin. Can serve as a substrate analog for submitochondrial particle ATPase activity (Km = 940uM). Induces a dose-dependent decrease in wild-type murine neural progenitor cell viability and an increase in caspase-3 activity. These effects are not observed in P2X7-/- mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 112898-15-4. Pack Sizes: 1mg. Molecular Formula: C??H??N?O??P? 3C?H??N. US Biological Life Sciences. | Worldwide |
| BzBzATP (BzATP) | BzBzATP (BzATP) is a P2X7 receptor agonist exhibits high potency at P2X1 receptor (pEC50 = 8.7). Synonyms: 2'/3'-O-(4-benzoylbenzoyl)adenosine-5'-triphosphate, tri(triethylammonium) salt. Grades: ≥ 95% by HPLC. Molecular formula: C24H24N5O15P3*3(C6H15N) [tri(triethylammonium salt)]; C24H24N5O15P3 (free acid). Mole weight: 1018.97 [tri(triethylammonium salt)]; 715.40 (free acid). | |
| b-Zeacarotene | b-Zeacarotene. Group: Biochemicals. Alternative Names: 7',8'-Dihydro-b,?-carotene. Grades: Highly Purified. CAS No. 514-89-6. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C40H58. US Biological Life Sciences. | Worldwide |
| Bz-FVR-AMC | Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a k cat /K m value of 1070 mM -1 s -1. The high concentration of BZ-FVR-AMC inhibits the substrate [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 88899-22-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1634. | |
| Bz-gly-D-lys-oh | Heterocyclic Organic Compound. CAS No. 108392-04-7. Molecular formula: C15H21N3O4. Mole weight: 307.34. Catalog: ACM108392047. | |
| Bz-Gly-Gly-OH | Bz-Gly-Gly-OH. Group: Biochemicals. Alternative Names: Hippuryl glycine; (N-Benzoylglycyl)glycine. Grades: Highly Purified. CAS No. 1145-32-0. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Bz-Gly-Gly-OH | Synonyms: Hippuryl glycine(N-Benzoylglycyl)glycine. Grades: ≥ 98% (HPLC). CAS No. 1145-32-0. Molecular formula: C11H12N2O4. Mole weight: 236.23. | |
| Bz-Gly-Gly-OH 98+% (HPLC) | Bz-Gly-Gly-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 1145-32-0. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
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