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| Product | Description | |
|---|---|---|
| CFM-2 | CFM-2. Group: Biochemicals. Grades: Purified. CAS No. 178616-26-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CFM-2 | Potent and selective AMPA antagonist. Synonyms: CFM-2; CFM 2; CFM2. Grades: >98%. CAS No. 178616-26-7. Molecular formula: C17H17N3O3. Mole weight: 311.34. |  |
| CFM 4 | CFM 4. Group: Biochemicals. Grades: Purified. CAS No. 331458-02-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CFM 4 | CFM 4 is a CARP-1 mimetic compound that inhibits CARP-1 binding to APC-2. It causes apoptosis and inhibition of cell growth in cancer cells. Synonyms: CFM-4; CFM 4; CFM4; 1-[(2-Chlorophenyl)methyl]-5'-phenyl-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one. Grades: ≥99% by HPLC. CAS No. 331458-02-7. Molecular formula: C22H16ClN3OS. Mole weight: 405.9. | |
| CFM-4 | CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G 2 M cell cycle arrest, and induces apoptosis with an IC 50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331458-02-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103255. |  |
| c-FMS inhibitor | c-FMS inhibitor is a novel c-Fms kinase inhibitor with a potential as anti-inflammatory agent and antirheumatic agent. Synonyms: 1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-. Grades: >98%. CAS No. 885704-21-2. Molecular formula: C23H30N6O. Mole weight: 406.52. | |
| CFO I | CFO I. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CFO I;RESTRICTION ENDONUCLEASES CFO I;restriction endonuclease cfo I from*clostridium;cfo i from clostridium formicoaceticum;restriction endonuclease Cfo I. Product Category: Heterocyclic Organic Compound. CAS No. 81811-52-1. Product ID: ACM81811521. Alfa Chemistry ISO 9001:2015 Certified. Categories: CFO India. |  |
| CFSE | CFSE Inhibitor. Uses: Scientific use. Product Category: T6802. CAS No. 150347-59-4. |  |
| CFTR activator 2 | CFTR activator 2 (WAY-326769) is an activator of mutant cystic fibrosis transmembrane conductance regulator (mutant-CFTR) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WAY-326769. CAS No. 871700-29-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-169536. | |
| CFTR Activator, Cact-A1 | A cell-permeable, non-toxic aminopyrazolocarbonitr i le compound that acts as a potent, selective, reversible and cAMP-independent activator of CFTR-dependent Cl- channel in airway epithelial cells (EC50 = 1.6uM in CFTR-expressing Fisher rat thyroid cells). Also shown to activate deltaF508-CFTR in primary CF-HBE cell cultures (EC50 = 3.5uM). Reported to directly bind to the same site as CFTRinh-172. Does neither elevate intracellular cAMP levels nor appear to have any requirement for cAMP agonist, such as forskolin. Shown to additively potentiate the G551D-CFTR Cl- current activated by forskolin with CFTR potentiator, VX-770. Exerts no effect on either Ca2+-activated Cl- channel (TMEM16A) or intracellular Ca2+ levels. Group: Biochemicals. Alternative Names: Cystic Fibrosis Transmembrane Conductance Regulator Activator, Cact-A1, 5-((Z)-2-(2-(Allyloxy)phenyl)-1-cyanovinyl)-3-amino-1H-pyrazole-4-carbonitrile, (Z)-3-(2-(2-(Allyloxy)phenyl)-1-cyanovinyl)-5-amino-1H-pyrazole-4-carbonitrile. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| CFTR corrector 15 | CFTR corrector 15 (Compound 4172) is a corrector for cystic fibrosis transmembrane conductance regulator ( CFTR ), that repairs the F508del-CFTR folding defect when used with VX-809 (HY-13262). CFTR corrector 15 can be used in research of cystic fibrosis disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1170387-92-4. Pack Sizes: 1 mg. Product ID: HY-164000. | |
| CFTR corrector 17 | CFTR corrector 17 (example 17) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator. CFTR corrector 17 can be used for the study of CFTR-mediated diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912790-04-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W984122. | |
| CFTR corrector 2 | CFTR corrector 2 is a cystic fibrosis transmembrane conductance corrector (CFTR) , extracted from patent US20140274933 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628416-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125381. | |
| CFTR(inh)-172 | CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel; reversibly inhibits CFTR short-circuit current in less than 2 minutes with a K i of 300 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 307510-92-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16671. | |
| CFTRinh 172 | CFTRinh 172. Group: Biochemicals. Grades: Purified. CAS No. 307510-92-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CFTRinh-172 | CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters. Synonyms: CFTR Inh-172; CFTR Inh 172; CFTR Inh172; CFTR(Inh)-172; CFTR(Inh) 172; CFTR(Inh)172; CFTR Inhibitor-172; CFTR Inhibitor 172; CFTR Inhibitor172. Grades: >98%. CAS No. 307510-92-5. Molecular formula: C18H10F3NO3S2. Mole weight: 409.4. | |
| CFTR Inhibitor-172 (CFTRinh-172, 3-[ (3-Trifluoromethyl) phenyl]-5-[ (4-carboxyphenyl) methylene]-2-thioxo-4-thiazolidinone) | A cell-permeable 2-thio-4-thiazolidinone compound that acts as a potent, reversible, rapid, and voltage-independent inhibitor of CFTR (cystic fibrosis transmembrane conductance regulator)-mediated Cl- transport in human airway cells (Ki ~300nM). It does not prevent elevation of cellular cAMP, nor does it inhibit non-CFTR Cl- channels, MDR-1, ATP-sensitive K+ channels, or a series of other transporters even at concentrations as high as 5uM. Shown to block cholera toxin-induced intestinal fluid secretion in mice. May be also useful for reducing intestinal fluid loss in other secretory diarrheas. Group: Biochemicals. Grades: Highly Purified. CAS No. 307510-92-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CG200745 | CG200745 is a novel hydroxamate-based pan-histone deacetylase inhibitor (HDACI). Like other inhibitors, CG200745 has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. CG200745 inhibited deacetylation of histone H3 and tubulin as much as vorinostat and belinostat did. CG200745 also inhibited growth of prostate cancer cells, increased sub-G1 population, and activated caspase-9, -3 and -8 in LNCaP, DU145 and PC3 cells. These results indicate that CG200745 induces apoptosis. The preclinical results show that combination treatment with docetaxel and new HDACI, CG200745, potentiated anti-tumor effect in hormone-refractory prostate cancer (HRPC) cells via activation of apoptosis. Synonyms: Ivaltinostat; CG-200745; CG-2; (E)-N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalen-1-yloxy)methyl)oct-2-enediamide. CAS No. 936221-33-9. Molecular formula: C24H33N3O4. Mole weight: 427.55. | |
| c[G(2',5')p-2'-AHC-A(3',5')p] | c[G(2',5')p-2'-AHC-A(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Synonyms: Cyclic (guanosine- (2' -≥ 5')- monophosphate- 2'- O- (6- aminohexylcarbamoyl)adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C27H38N12O14P2 (free acid). Mole weight: 816.6 (free acid). | |
| c[G(2',5')p-2'-Biotin-16-A(3',5')p] | c[G(2',5')p-2'-Biotin-16-A(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grades: ≥ 95% by HPLC. Molecular formula: C43H63N15O17P2S (free acid). Mole weight: 1156.1 (free acid). | |
| c[G(2',5')p-2'-dA(3',5')p] | c[G(2',5')p-2'-dA(3',5')p] is a 2'-deoxy analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING stimulator, which can be used for studying ligand-receptor interactions. Synonyms: Cyclic (guanosine- (2' -≥ 5')- monophosphate- 2'- deoxyadenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O12P2 (free acid). Mole weight: 658.4 (free acid). | |
| c[G(2',5')p-2'-Fluo-AHC-A(3',5')p] | c[G(2',5')p-2'-Fluo-AHC-A(3',5')p] is a fluorescent analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. Synonyms: Cyclic (guanosine- (2'?5') -monophosphate-2'-O- (6-[fluoresceinyl]aminohexylcarbamoyl) adenosine- (3'?5') -monophosphate) , sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C48H48N12O20P2. Mole weight: 1174.9. | |
| c[G(2',5')p-ε-A(3',5')p] | c[G(2',5')p-ε-A(3',5')p] is a fluorescent analogue of c[G(2',5')pA(3',5')p]. Grades: ≥ 95% by HPLC. Molecular formula: C22H24N10O13P2 (free acid). Mole weight: 698.4 (free acid). | |
| c[G(2',5')pG(2',5')p] | c[G(2',5')pG(2',5')p] is a cyclic dinucleotide analogue of c-diGMP, the bacterial second messenger. Synonyms: Cyclic diguanosine- (2' -≥ 5')- monophosphate / cyclic bis (2' -≥ 5') diguanylic acid, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 389873-75-0. Molecular formula: C20H24N10O14P2 (free acid). Mole weight: 690.4 (free acid). | |
| c[G(2',5')pS-A(3',5')pS], isomer 1 and isomer 2 | c[G(2',5')pS-A(3',5')pS] is an isomeric di-thiophosphate analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is resistant against the 2'3'-cGAMP hydrolysing enzyme ENPP1, and compared to natural 2'3'-cGAMP, it exhibits higher potency in inducing IFN-β secretion from human THP1 monocytes. Grades: ≥ 95% by HPLC. CAS No. 1638242-56-4 / 1638243-00-1. Molecular formula: C20H24N10O11P2S2 (free acid). Mole weight: 706.6 (free acid). | |
| CGA 41-60 | CGA 41-60 has antifungal activity. The source of CGA 41-60 is synthetic construct. Synonyms: chromogranin A 41-60. Grades: >95% by HPLC. | |
| CGA 41-70 | The source of CGA 41-70 is synthetic construct. CGA 41-70 has antifungal activity against N.crassa (MIC=7 microM), A. brassicicola (MIC=7 microM), N.hematococca (MIC=7 microM), F.culmorum (MIC=10 microM), F.oxyporum (MIC=30 microM), and T.mentagrophytes (MIC=30 microM). Synonyms: chromogranin A 41-70. | |
| CGA 47-60 | CGA 47-60 has antifungal activity. The source of CGA 47-60 is synthetic construct. Synonyms: chromogranin A 47-60. Grades: >98% by HPLC. | |
| CGA 47-70 | The source of CGA 47-70 is synthetic construct. It has antifungal activity against N.crassa (MIC=5 microM), A.fumigatus (MIC=30 microM), A. brassicicola (MIC=10 microM), N.hematococca (MIC=7 microM), F.culmorum (MIC=10 microM), F.oxyporum (MIC=30 microM), and T.mentagrophytes (MIC=30 microM). Synonyms: chromogranin A 47-70. | |
| cGAMP | cGAMP (Cyclic GMP-AMPP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cyclic GMP-AMP; 3',3'-cGAMP. CAS No. 849214-04-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12512. | |
| cGAS-IN-2 | cGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC 50 of 0.01512 μM for h-cGAS [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765273-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160546. | |
| CGC-11047 | CGC-11047 is a second generation polyamine analogue, synthesized through the restriction of molecular conformations of parent polyamine compounds, with potential antineoplastic activity. Polyamine analogue PG11047 may displace endogenous polyamines from DNA binding sites, thereby interfering with cell cycle processes dependent upon polyamine binding and function, and resulting in cell-cycle arrest, induction of apoptosis, depletion of polyamines, and interference with gene and ligand-receptor activities involved with cell growth. This agent may exhibit decreased toxicity and enhanced cytotoxicity profiles compared to first-generation polyamine compounds. In tumor cells, there is an increase dependence on polyamines as well as a dysregulated polyamine metabolic pathway resulting in abnormal or sustained tumor growth. Synonyms: CGC 11047; CGC11047; SL 11047; SL 47; SL47. CAS No. 206991-64-2. Molecular formula: C14H36Cl4N4. Mole weight: 402.27. | |
| CGGRGD acetate | CGGRGD acetate is a RGD derivative with cysteine as the n-terminal. CGGRGD was synthesized by solid phase peptide synthesis technology, and amino2-cyanobenzothiazole (2-cyanobenzothiazole) (2-cyanobenzothiazole (CBT) was added on the surface of PCL fiber for ammoniation. Molecular formula: C21H37N9O11S. Mole weight: 623.65. | |
| Cgh 2466 | Cgh 2466. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGH 2466, CID5282339, C14128, LS-192831, BRD-K82028950-300-01-1, 252198-68-8. Product Category: Heterocyclic Organic Compound. CAS No. 252198-68-8. Molecular formula: C14H9N3SCl2.2HCl. Mole weight: 322.21236. Purity: >99 %. IUPACName: 4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1,3-thiazol-2-amine. Canonical SMILES: C1=CC(=C(C=C1C2=C(SC(=N2)N)C3=CC=NC=C3)Cl)Cl. Density: 1.45g/cm³. Product ID: ACM252198688. Alfa Chemistry ISO 9001:2015 Certified. | |
| CGH 2466 dihydrochloride | CGH 2466 dihydrochloride is an adenosine A1, A2B and A3 receptor antagonist (IC50 = 19, 21, and 80 nM, respectively). It also displays an inhibitory effect on p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 is potentially used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Uses: Potential treatment of asthma and copd. Synonyms: CGH 2466 dihydrochloride; CGH2466 dihydrochloride; CGH-2466 dihydrochloride; 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1177618-54-0. Molecular formula: C14H9N3SCl2.2HCl. Mole weight: 395.13. | |
| CGH 2466 dihydrochloride | CGH 2466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1177618-54-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGI1746; CGI-1746; CGI 1746. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69. Purity: >98%. IUPACName: 4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Canonical SMILES: O=C(NC1=CC=CC(C(N=C2NC3=CC=C(C(N4CCOCC4)=O)C=C3)=CN(C)C2=O)=C1C)C5=CC=C(C(C)(C)C)C=C5. Product ID: ACM910232847. Alfa Chemistry ISO 9001:2015 Certified. | |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Synonyms: CGI1746; CGI-1746; CGI 1746. 4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Grades: 98%. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69. | |
| CGI560 | CGI560 is a potent BTK inhibitor with IC50 = 400 nM for BTK. Synonyms: CGI-560; CGI 560; 4-(tert-Butyl)-N-(3-(8-(phenylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)benzamide. CAS No. 845269-74-1. Molecular formula: C29H27N5O. Mole weight: 461.57. | |
| CGK733 | CGK733. Group: Biochemicals. Alternative Names: α -Phenyl-N- [2, 2, 2-trichloro-1- [ [ [ (4-fluoro-3-nitrophenyl) amino] thioxomethyl] amino] ethyl] benzeneacetamide. Grades: Highly Purified. CAS No. 905973-89-9. Pack Sizes: 5mg. Molecular Formula: C23H18Cl3FN4O3S, Molecular Weight: 555.84. US Biological Life Sciences. | Worldwide |
| CGK733 | CGK733, a thiourea-containing compound, was originally identified as a specific inhibitor of ATR and ATM kinases (IC50 = ~ 200 nM). In prematurely senescent breast, lung, and colon cancer cells CGK733 reportedly suppresses ATM-mediated p21 expression required for survival, resulting in cell death. Synonyms: CGK733; CGK-733; CGK 733. CAS No. 905973-89-9. Molecular formula: C23H18Cl3FN4O3S. Mole weight: 555.84. | |
| CGK 733 | CGK 733. Group: Biochemicals. Grades: Purified. CAS No. 905973-89-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGM097 | CGM097 is an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, p53/HDM2 interaction inhibitor CGM097 inhibits the binding of the HDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53. By preventing this HDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of p53 signaling and, thus, the p53-mediated induction of tumor cell apoptosis. HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Synonyms: CGM097; CGM-097; CGM 097; NVPCGM097; NVPCGM 097; NVPCGM-097; NVP CGM097; NVP CGM 097; NVP CGM-097. CAS No. 1313363-54-0. Molecular formula: C38H47ClN4O4. Mole weight: 659.27. | |
| cgMolluscidin | CgMolluscidin is a novel dibasic residue repeat rich antimicrobial peptide, purified from the gill of the Pacific oyster, Crassostrea gigas. CgMolluscidin showed potent antimicrobial activity against both Gram-positive bacteria, including Bacillus subtilis, Micrococcus luteus, and Staphylococcus aureus (minimal effective concentrations [MECs]; 1.3-31.3 μg/mL), and Gram-negative bacteria, including Escherichia coli, Salmonella enterica, and Vibrio parahaemolyticus ([MECs]; 0.4-2.3 μg/mL), without hemolytic activity. | |
| cGMP | cGMP, a cyclic guanosine monophosphate, possesses an essential role in governing numerous physiological processes. Significantly employed as a pharmacological focal point in the biomedical realm to combat the likes of hypertension and pulmonary arterial hypertension, its potency is immense. Furthermore, it is intricately involved in the signal transduction pathways of selected neurotransmitters and hormones. Synonyms: Guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H12N5O7P (free acid). Mole weight: 345.20 (free acid). | |
| cGMP-AM | cGMP-AM is a precursor of cGMP, the second messenger. The polar active analogue is released after the metabolism of cGMP-AM by esterases. Synonyms: Guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 95% by HPLC for mixture of isomers. CAS No. 164007-71-0. Molecular formula: C13H16N5O9P. Mole weight: 417.3. | |
| cGMP Dependent Kinase Inhibitor Peptide | PKG Inhibitor is a competitive inhibitor of cGMP-dependent protein kinase (PKG). It is an analog of a substrate peptide corresponding to a phosphorylation site of histone H2B, and inhibits phosphorylation of intact histones by PKA. Synonyms: cGMP Dependent Kinase Inhibitor Peptide. Grades: >98%. CAS No. 82801-73-8. Molecular formula: C38H74N18O10. Mole weight: 943.12. | |
| cGMP Dependent Kinase Inhibitor Peptide | cGMP Dependent Kinase Inhibitor Peptide. Group: Biochemicals. Grades: Purified. CAS No. 82801-73-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| cGMP-dependent protein kinase | CGMP is required to activate this enzyme. The enzyme occurs as a dimer in higher eukaryotes. The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites. This domain catalyses the phosphorylation by ATP to specific serine or threonine residues in protein substrates. The enzyme also has two allosteric cGMP-binding sites (sites A and B). Binding of cGMP causes a conformational change that is associated with activation of the kinase. Group: Enzymes. Synonyms: 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Enzyme Commission Number: EC 2.7.11.12. CAS No. 141588-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3131; cGMP-dependent protein kinase; EC 2.7.11.12; 141588-27-4; 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Cat No: EXWM-3131. |  |
| Cgp-11130 | Cgp-11130 is a GABAB receptor agonist which was never marketed. It is selective for the GABAB receptor over the GABAA receptor (IC50 = 1.70 μM and > 100 μM, respectively). Synonyms: Cgp 11130; Cgp11130; β-(Aminomethyl)-4-fluorobenzenepropanoic acid. Grades: 98%. CAS No. 52237-19-1. Molecular formula: C10H12FNO2. Mole weight: 197.21. | |
| Cgp-11952 | Cas No. 64078-09-7. | |
| CGP 12177 | CGP 12177 is a partial β3-adrenoceptor agonist with Ki value of 88 nM. It is also an of β1- and β2-adrenoceptors antagonist with Ki values of 0.9 nM and 4 nM for β1-, β2adrenoceptors. CGP12177 can slightly activate L-type Ca2+ current in human ventricular myocytes. Uses: Adrenergic beta-antagonists. Synonyms: CGP 12177; CGP12177; CGP-12177; Tbhpbo; CGP 12177 Hydrochloride; CGP 12177 HCl. 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one;64208-32-8(hydrochloride). Grades: 98%. CAS No. 81047-99-6. Molecular formula: C14H21N3O3. Mole weight: 279.34. | |
| CGP 12177 hydrochloride | CGP 12177 hydrochloride is a partial agonist of β3-adrenoceptors, and also an antagonist of β1- and β2-adrenoceptors (Ki = 0.9, 4 and 88 nM for β1, β2 and β3 receptors respectively). Synonyms: CGP 12177 hydrochloride; CGP12177 hydrochloride; CGP-12177 hydrochloride; 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride. CAS No. 64208-32-8. Molecular formula: C14H21N3O3.HCl. Mole weight: 315.8. | |
| CGP 12177 hydrochloride | CGP 12177 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64208-32-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 12177 hydrochloride | CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-CGP 12177 hydrochloride. CAS No. 64208-32-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101393A. | |
| CGP-12388 | CGP-12388 is a beta-adrenoceptor antagonist-derived radioligands. It is used for cardiac PET imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Uses: Cgp-12388 is used for cardiac pet imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Synonyms: 4-(3-(Isopropylamino)-2-Hydroxypropoxy)-2H-Benzimidazol-2-One;Cgp 12388; Cgp-12388; Cgp12388;2H-Benzimidazol-2-one, 4-(3-(isopropylamino)-2-hydroxypropoxy)-;4-[2-hydroxy-3-(propan-2-ylamino)propoxy]benzimidazol-2-one. Grades: 95%. CAS No. 108929-47-1. Molecular formula: C13H19N3O3. Mole weight: 263.29. | |
| Cgp 13143 | Cgp 13143 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 13143; Cgp13143; Cgp-13143. ((4-methyl-2-oxo-2H-1-benzopyran-6-yl)amino)oxo-Acetic acid. Grades: 98%. CAS No. 75919-69-6. Molecular formula: C12H9NO5. Mole weight: 247.21. | |
| Cgp 13231 | Cgp 13231 is the N-oxide metabolite of amocarzine. Synonyms: Cgp 13231; Cgp13231; Cgp-13231. 1-Piperazinecarbothioamide, 4-methyl-N-(4-((4-nitrophenyl)amino)phenyl)-4-oxide. Grades: 98%. CAS No. 113962-61-1. Molecular formula: C18H21N5O3S. Mole weight: 387.46. | |
| CGP 13501 | CGP 13501. Group: Biochemicals. Grades: Purified. CAS No. 56189-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 13501 | CGP 13501 is a positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type. Uses: Gaba-b receptor agonists. Synonyms: CGP13501; CGP 13501; CGP-13501; 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal. Grades: ≥98% by HPLC. CAS No. 56189-68-5. Molecular formula: C19H30O2. Mole weight: 290.44. | |
| Cgp 15425 | Cgp 15425 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 15425; Cgp15425; Cgp-15425. (S)-N1-((2S,5S,8R,11S,14S,17S)-8-((1H-indol-3-yl)methyl)-11-(4-aminobutyl)-5,17-dibenzyl-14-((R)-1-hydroxyethyl)-19-imino-3,6,9,12,15,18,22-heptaoxo-1-phenyl-4,7,10,13,16-pentaazadocosan-2-yl)-2-aminosuccinamide. Grades: 98%. CAS No. 76080-70-1. Molecular formula: C56H69N11O10. Mole weight: 1056.21. | |
| CGP-15720 hydrochloride | CGP-15720 is a antitumor agent. Uses: Antitumor. Synonyms: CGP-15720 hydrochloride; CGP-15720 HCl; CGP-15720A; CGP15720A; UNII-73G6V7978M. 4-(3-(2-(2-(pyridin-4-yl)-4,5-dihydro-1H-imidazol-1-yl)ethyl)ureido)benzoic acid hydrochloride. Grades: 98%. CAS No. 76692-12-1. Molecular formula: C18H20ClN5O3. Mole weight: 389.84. | |
| Cgp-17520 | Cgp-17520 is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: Cgp 17520; Cgp-17520; Cgp17520. 7-(2-(4-(((2-Amino-2-carboxyethoxy)carbonyl)amino)phenyl)-2-hydroxyacetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt. Grades: >98 %. CAS No. 101706-66-5. Molecular formula: C22H24N8NaO9S2. Mole weight: 631.59. | |
| CGP-1758 monomethanesulfonate | CGP-1758 monomethanesulfonate is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: CGP 1758B; CGP-1758B; CGP1758B. 2-Hydroxy-5- [2- [ [2-hydroxy-3- [4- (2-methoxyethoxy) phenoxy] propyl] amino] ethoxy] benzamide monomethanesulfonate;CGP1758 monomethanesulfonate. Grades: >98%. CAS No. 108289-44-7. Molecular formula: C22H32N2O10S. Mole weight: 516.56. | |
| Cgp 20309 | Cgp 20309 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 20309; Cgp20309; Cgp-20309. N-(2-(1,1-dimethylethyl)-5-methoxy-6-benzothiazolyl)-4-methyl-1-Piperazinecarbothioamide. Grades: 98%. CAS No. 122378-48-7. Molecular formula: C18H26N4OS2. Mole weight: 378.56. | |
| CGP 20376 | CGP 20376 is a benzothiazole compound and it has antifilarial properties. Uses: Antifilarial agent. Synonyms: CGP 20376; CGP20376; CGP-20376. 3- ( ( ( (2- (1, 1-dimethylethyl) -5-methoxy-6-benzothiazolyl) amino) thioxomethyl) thio) -Propanoic acid;N-(2-tert-Butyl-5-methoxybenzothiazol-6-yl)dithiocarbonic acid 5-(1-carboxyethyl)ether. Grades: 98%. CAS No. 81059-04-3. Molecular formula: C16H20N2O3S3. Mole weight: 384.54. | |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216905-73-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride is a highly selective β1-adrenoceptor antagonist with an IC 50 of 0.7 nM. CGP 20712 dihydrochloride exhibits ~10,000-fold selectivity over β2-adrenoceptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216905-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101355A. | |
| CGP 20712 dihydrochloride | CGP 20712 dihydrochloride is a potent and selective β1-adrenoceptor antagonist (IC50 = 0.7 nM) with 10,000-fold selectivity over β2-adrenoceptors. Synonyms: CGP 20712A Dihydrochoride; CGP 20712ADihydrochoride; CGP 20712A; CGP20712A; CGP-20712A. SR-01000076208; 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride. Grades: ≥96% by HPLC. CAS No. 1216905-73-5. Molecular formula: C23H25F3N4O5.2HCl. Mole weight: 567.39. | |
| Cgp 21833 | Cgp 21833 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 21833; Cgp-21833; Cgp21833. 1-(2-(1,1-dimethylethyl)-5-methyl-6-benzothiazolyl)-2-methylhydrazide 1-Piperazinecarbothioic acid. Grades: 98%. CAS No. 122378-49-8. Molecular formula: C18H27N5S2. Mole weight: 377.57. | |
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