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| Product | Description | |
|---|---|---|
| CGP7930 | CGP7930 is a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB. It increases the potency and efficacy of GABA at both native and recombinant GABAB receptors with EC50 values of 5.37 and 4.60μM respectively. It also enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons. It reduces operant self-administration of ethanol and cocaine in rats. Uses: Cgp7930 has anxiolytic effects in animal studies, and has a synergistic effect with gabab agonists such as baclofen and ghb. it reduces operant self-administration of ethanol and cocaine in rats. Synonyms: 3,5-Bis(1,1-dimethylethyl)-4-hydroxy-beta,beta-dimethylbenzenepropanol;2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol;3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol;CGP7930; CGP-7930; CGP 7930. Grades: >98 %. CAS No. 57717-80-3. Molecular formula: C19H32O2. Mole weight: 292.46. |  |
| CGP7930 | CGP7930 (3-(3,5-Di-tert-butyl-4-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57717-80-3. Pack Sizes: 1 mg. Product ID: HY-103502. |  |
| CGP 7930 | CGP 7930. Group: Biochemicals. Grades: Purified. CAS No. 57717-80-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CGP 7930 (GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930) | A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 57717-80-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP-79807 | CGP-79807 is a potent CDC2 protein kinase inhibitor that originated by Novartis. In Sep 2000, Preclinical development for Cancer in Switzerland was on-going, but no development has been reported. Uses: Cancer. Synonyms: CGP-79807; CGP 79807; CGP79807; UNII-532R2SRL4B; CHEMBL172140; 532R2SRL4B; SCHEMBL5842014; SCHEMBL5842019; BDBM50073763. 3-((9-ethyl-2-((trans-4-hydroxycyclohexyl)amino)-9H-purin-6-yl)amino)-Benzonitrile. Grades: 98%. CAS No. 1229665-91-1. Molecular formula: C20H23N7O. Mole weight: 370.44. | |
| Cgp-8065 | Cgp-8065 is a filaricidal compound and a dithiocarbamate-derivative of amoscanate. Synonyms: Cgp 8065; Cgp8065; N-(4-(4'-Nitroanilino)phenyl) S-(beta-carboxyethyl)dithiocarbamate. Grades: 98%. CAS No. 62939-04-2. Molecular formula: C16H15N3O4S2. Mole weight: 377.43. | |
| Cgp 8716 | Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis. Synonyms: Cgp 8716; Cgp8716; Cgp-8716. 4-(2-(1,1-dimethylethyl)-5-(3-pyridinyl)-1H-imidazol-4-yl)-Phenol. Grades: 98%. CAS No. 84782-21-8. Molecular formula: C18H19N3O. Mole weight: 293.36. | |
| CGP-9000 | CGP-9000 is a semisynthetic cephalosporin which has a wide antibacterial spectrum. Its antibacterial activity was similar to that of cefalexin in vitro, but the effect of oral administration was 2-7 times stronger than that of cefalexin and cefradine in mice. Synonyms: CGP 9000; BRN 0587499. Molecular formula: C16H19N3O5S. Mole weight: 365.40. | |
| Cg-Prp | Cg-Prp is the resulting 37-amino acid peptide composed of an acidic region and a cationic proline-rich region. | |
| CGRP 8-37 (human) | CGRP 8-37 (human) is a peptide antagonist for CGRP1 receptors. Uses: Miotics. Synonyms: FBHuman; HCGRP-(8-37); HY-P1014; HY P1014; HYP1014; CGRP 8 37. Grades: >95%. CAS No. 119911-68-1. Molecular formula: C139H230N44O38. Mole weight: 3125.6. | |
| CGRP 8-37 (human) | CGRP 8-37 (human). Group: Biochemicals. Grades: Purified. CAS No. 119911-68-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| CGRP 8-37 (rat) | CGRP 8-37 (rat). Group: Biochemicals. Grades: Purified. CAS No. 129121-73-9. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| CGRP (rat) | CGRP (rat). Group: Biochemicals. Grades: Purified. CAS No. 83651-90-5. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| CGRP (rat) | α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects. Synonyms: Calcitonin Gene-Related Peptide (rat). Grades: >95%. CAS No. 83651-90-5. Molecular formula: C162H262N50O52S2. Mole weight: 3806.3. | |
| CGS 12066B dimaleate | CGS 12066B dimaleate. Group: Biochemicals. Grades: Purified. CAS No. 109028-10-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 12066B dimaleate | CGS 12066B dimaleate is a 5-HT1B full agonist, which is 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Uses: Serotonin receptor agonists. Synonyms: CGS 12066B dimaleate; CGS12066B dimaleate; CGS-12066B dimaleate; 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate. Grades: ≥98% by HPLC. CAS No. 109028-10-6. Molecular formula: C17H17F3N4.2C4H4O4. Mole weight: 566.49. | |
| CGS 15943 | CGS 15943. Group: Biochemicals. Grades: Purified. CAS No. 104615-18-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 15943 | CGS 15943 is a potent and orally bioactive adenosine receptor antagonist (Ki = 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors, respectively). Synonyms: CGS 15943; CGS15943; CGS-15943; 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine. Grades: ≥99% by HPLC. CAS No. 104615-18-1. Molecular formula: C13H8ClN5O. Mole weight: 285.69. | |
| CGS 19755 | CGS 19755. Group: Biochemicals. Grades: Purified. CAS No. 110347-85-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 19755 | CGS 19755 is a potent and competitive NMDA receptor antagonist with anticonvulsant, anxiolytic, analgesic and neuroprotective activity. Synonyms: CGS-19755; CGS 19755; CGS19755; CPDD 0027; CPDD-0027; CPDD0027; Selfotel; cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid. CAS No. 110347-85-8. Molecular formula: C7H14NO5P. Mole weight: 223.17. | |
| CGS20625 | CGS-20625 is an anxiolytic drug used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It produces anxiolytic and anticonvulsant effects, but with no sedative effects even at high doses, and no significant muscle relaxant effects. It is orally active in humans, but with relatively low bioavailability. CGS-20625 is a positive allosteric modulator at several GABAA receptors types. Due to its alicyclic moiety potency at γ1 subunit, containing receptor types is more pronounced for CGS-20625 compared to benzodiazepines. γ1 subunits are expressed at higher levels in the central amygdala. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGS20625; CGS-20625; CGS 20625. Product Category: Others. Appearance: Solid powder. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.37. Purity: >98%. IUPACName: Cyclohepta(b)pyrazolo(3,4-d)pyridin-3(2H)-one, 5,6,7,8,9,10-hexahydro-2-(4-methoxyphenyl)-. Canonical SMILES: O=C1N(C2=CC=C(OC)C=C2)N=C3C(CCCCC4)=C4NC=C31. Product ID: ACM111205551-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CGS 20625 | CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine receptor agonist (IC50 = 1.3 nM) with no affinity for other neurotransmitter receptor binding sites. Uses: Anti-anxiety drug. Synonyms: CGS 20625; CGS20625; CGS-20625; 5, 6, 7, 8, 9, 10-Hexahydro-2- (4-methoxyphenyl) cyclohepta[b]pyrazolo[3, 4-d]pyridin-3 (2H) -one. Grades: ≥99% by HPLC. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| CGS 20625 | CGS 20625. Group: Biochemicals. Grades: Purified. CAS No. 111205-55-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 21680 | CGS 21680, an A2 adenosine receptor selective agonist, has been found to be probably effective in inducing vasorelaxation and increasing in heart rate. Uses: Cgs 21680 is an a2 adenosine receptor selective agonist that has been found to be probably effective in inducing vasorelaxation and increasing in heart rate. Synonyms: Cgs 21680; CGS-21680; CGS21680; 2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine; UNII-T5HB1E831H; CHEMBL331372. Grades: 95%. CAS No. 120225-54-9. Molecular formula: C23H29N7O6. Mole weight: 499.52. | |
| CGS 21680A | CGS 21680A. Group: Biochemicals. Alternative Names: CGS 21680 hydrochloride; 4- [2- [ [6-Amino-9- (N-ethyl-b-D-ribofuranuronamidosyl) -9H-purin-2-yl] amino] ethyl] benzenepropanoic acid hydrochloride. Grades: Highly Purified. CAS No. 124431-80-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H30ClN7O6. US Biological Life Sciences. | Worldwide |
| CGS 21680C Sodium Salt | A selective A2A receptor agonist. Uses: A selective a2a receptor agonist. Synonyms: 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic Acid Monosodium Salt. Grades: 95%. CAS No. 120225-64-1. Molecular formula: C23H28N7NaO6. Mole weight: 521.5. | |
| CGS 21680 hydrochloride | CGS 21680 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 124431-80-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 21680 Hydrochloride | CGS 21680 Hydrochloride is a selective adenosine A2A receptor agonist with a K i of 27 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 124431-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13201A. | |
| CGS 21680 Hydrochloride | CGS 21680 Hcl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. Synonyms: CGS 21680 Hydrochloride; CGS21680 Hydrochloride; CGS-21680 Hydrochloride. Grades: >98%. CAS No. 124431-80-7. Molecular formula: C23H29N7O6.HCl. Mole weight: 535.98. | |
| CGS 35066 | CGS 35066. Group: Biochemicals. Grades: Purified. CAS No. 261619-50-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGS 35066 | CGS 35066 is a potent endothelin-converting enzyme (ECE) inhibitor with > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 = 22 and 2300 nM, respectively). It blocks the hypertensive effects induced by big ET-1 in vitro and reduces the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH). Synonyms: CGS 35066; CGS35066; CGS-35066; α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid; (2S)-3-dibenzofuran-3-yl-2-(phosphonomethylamino)propanoic acid. Grades: ≥99% by HPLC. CAS No. 261619-50-5. Molecular formula: C16H16NO6P. Mole weight: 349.28. | |
| cgs-8216 | cgs-8216. Uses: For analytical and research use. Group: Impurity standards. CAS No. 77779-60-3. Molecular Formula: C16H11N3O. Mole Weight: 261.28. Catalog: APB77779603. |  |
| CGS 8216 | CGS 8216, a benzodiazepine receptor antagonist, inhibits 3 H-flunitrazepam ( 3 H-FLU) binding to rat synaptosomal membranes in vitro at subnanomolar concentrations [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77779-60-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121116. | |
| CGS 9343B | CGS 9343B is a calmodulin (CaM) antagonist that inhibits calmodulin-stimulated cAMP phosphodiesterase activity (IC50 = 3.3 nM). It also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR. Synonyms: CGS 9343B; CGS9343B; CGS-9343B; Zaldaride Maleate; 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate. Grades: ≥98% by HPLC. CAS No. 109826-27-9. Molecular formula: C26H28N4O2.C4H4O4. Mole weight: 544.61. | |
| CGS 9343B | CGS 9343B. Group: Biochemicals. Grades: Purified. CAS No. 109826-27-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CH0076989 | CH0076989 is a small molecule agonist for CCR3. It activates a number of signalling pathways including chemotaxis and receptor internalisation. Uses: Ch0076989 activates a number of signalling pathways including chemotaxis and receptor internalisation. Synonyms: CH-0076989; CH 0076989; CH0076989; UNII-9E629B19WL; CHEMBL485834; 9E629B19WL;4-(2-(Benzofuran-4-yl)acetamido)-2-bromo-1-(3-phenylpropyl)pyridin-1-ium bromide. Grades: 98%. CAS No. 54371-52-9. Molecular formula: C24H22Br2N2O2. Mole weight: 530.25. | |
| CH100 | CH100 is a Chinese herbal medicine. It is previously used in the treatment of human hepatitis C. Uses: Ch100 is used in the treatment of human hepatitis c. Synonyms: CH 100; CH-100; 2-Propanamine, N-(1-methylethyl)-, (4-chlorophenoxy)acetate; Acetic acid, (4-chlorophenoxy)-, compd. with N-(1-methylethyl)-2-propanamine (1:1). Grades: 98%. CAS No. 51346-20-4. Molecular formula: C14H22ClNO3. Mole weight: 287.78. | |
| CH-102 | CH-102 is an isoquinoline derivative. It could inhibit platelet aggregation. Uses: Ch-102 could inhibit platelet aggregation. Synonyms: CH 102; CH102; (3z)-3-imino-8,9-dimethoxy-5,6-dihydro[1,3]thiazolo[4,3-a]isoquinoline-1-carbonitrile; 5,6-Dihydro-3-imino-8,9-dimethoxythiazolo[4,3-a]isoquinoline-1-carbonitrile. Grades: 98%. CAS No. 55393-37-8. Molecular formula: C14H13N3O2S. Mole weight: 287.34. | |
| CH 141 | CH 141 is a peripheral vasodilator. Uses: Peripheral vasodilator. Synonyms: 6-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)-3-phenyl-5,6-dihydro-2H-1,2,4-oxadiazine; CH 141; CH-141; CH141; Pthiqdo. Grades: 98%. CAS No. 78279-88-6. Molecular formula: C19-H21-N3-O. Mole weight: 307.39. | |
| CH 150 | CH 150 is a bio-active chemical, but detailed information has not been published. Synonyms: CH 150; CH150; CH-150. 3-Ethyl-2,6-dimethyl-4H-pyrido(1,2-a)pyrimidin-4-one. Grades: 98%. CAS No. 70381-44-1. Molecular formula: C12H14N2O. Mole weight: 202.26. | |
| CH-200 | CH-200 is used as a new antiarrhythmic drug. It suppressed arrhythmia more effectively than did procainamide and lidocaine in beagle dogs. Uses: Ch-200 is used as a new antiarrhythmic drug. Synonyms: CH200; CH 200; 5-Phenacylthieno(3,2-c)pyridinium chloride; 5-(2-Oxo-2-phenylethyl)thieno(3,2-c)pyridinium chloride. Grades: 98%. CAS No. 64955-45-9. Molecular formula: C15H12ClNOS. Mole weight: 289.78. | |
| CH 223191 | CH 223191 is a specific and potent antagonist to the aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor that is involved in drug and xenobiotic metabolism. Unlike other AhR antagonists, it does not react with the estrogen receptor and is observed to effect AhR-dependent reporter gene expression in human, mouse, rat, and guinea pig cell lines. CH223191 is reported to exhibit AHR-independent pro-proliferative properties. Group: Biochemicals. Alternative Names: AhR Antagonist, CH223191, AGN-PC-0KP4EW, Aryl hydrocarbon receptor antagonist; 2-methyl-N- [2-methyl-4- [ (2-methylphenyl) diazenyl] phenyl] pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 301326-22-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H19N5, Molecular Weight: 333.4. US Biological Life Sciences. | Worldwide |
| CH-223191 | CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor ( AhR ). CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC 50 of 0.03 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301326-22-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12684. | |
| CH-223191 | CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.CH223191 can prevent 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. CH223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR. These inhibitory effects of CH-223191 prevented the expression of cytochrome P450 enzymes, target genes of the AhR. CH-223191, may be a useful agent for the study of AhR-mediated signal transduction and the prevention of TCDD-associated pathology. Synonyms: CH223191; CH-223191; CH 223191. Grades: >98%. CAS No. 301326-22-7. Molecular formula: C19H19N5O. Mole weight: 333.39. | |
| CH 275 | CH 275 is a potent somatostatin receptor 1 (sst1) agonist (IC50 = 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). It attenuates somatostatin release in the rat nucleus accumbens. Synonyms: CH 275; CH275; CH-275. CAS No. 174688-78-9. Molecular formula: C74H96N14O15S2. Mole weight: 1485.8. | |
| CH2COOH-PEG2-CH2COOH | CH2COOH-PEG2-CH2COOH. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 13887-98-4. Molecular formula: C8H14O7. Mole weight: 222.19. Purity: 95%+. Product ID: ACM13887984-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3,6,9-Trioxaundecanedioic acid. | |
| CH2COOH-PEG4-CH2COOH | CH2COOH-PEG4-CH2COOH. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 77855-75-5. Molecular formula: C12H22O9. Mole weight: 310.3. Purity: 95%+. Product ID: ACM77855755. Alfa Chemistry ISO 9001:2015 Certified. | |
| CH2COOH-PEG5-CH2COOH | CH2COOH-PEG5-CH2COOH. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 77855-76-6. Molecular formula: C14H26O10. Mole weight: 354.35. Purity: 95%+. Product ID: ACM77855766. Alfa Chemistry ISO 9001:2015 Certified. Categories: 77855-75-5. | |
| CH3NH3PbBr3; Perovskite CH3NH3PbBr3 Powder, >99% | CH3NH3PbBr3; Perovskite CH3NH3PbBr3 Powder, >99%. Group: other glass and ceramic materials. CAS No. 69276-13-7. |  |
| CH3NH3PbICl2(MAPbICl2 )Methylammonium Lead Chloride Iodide, >99% | CH3NH3PbICl2(MAPbICl2 )Methylammonium Lead Chloride Iodide, >99%. Group: other glass and ceramic materials. CAS No. 1472068-56-6. | |
| CH-401Na | CH-401Na is a bio-active chemical compound. Synonyms: CH 401Na; CH-401-Na; CH401-Na; 1-(2-Hydroxy-4-(3-sulfopropyloxy)phenyl)-3-(3-hydroxy-4-methoxyphenyl)-1-propanone sodium salt. Grades: 98%. CAS No. 59881-19-5. Molecular formula: C19H21NaO8S. Mole weight: 432.42. | |
| CH 402 | CH 402 can inhibit lipid peroxidation. Synonyms: CH 402; CH402; CH-402. 4-Quinolinemethanesulfonic acid, 1,2-dihydro-2,2-dimethyl-, monosodium salt. Grades: 98%. CAS No. 75903-70-7. Molecular formula: C12H15NO3S.Na. Mole weight: 275.30. | |
| CH5015765 | CH5015765 is a novel potent and selective HSP90 inhibitor. CH5015765, which showed high affinity for Hsp90 and antitumor activity in human cancer xenograft mouse models. Synonyms: CH-5015765; CH 5015765; 4-(5-chloro-1,3-dihydrobenzo[de]isochromen-6-yl)-6-(methylthio)-1,3,5-triazin-2-amine. Grades: 98%. CAS No. 959766-47-3. Molecular formula: C16H13ClN4OS. Mole weight: 344.82. | |
| CH5132799 | CH5132799 is a novel class I PI3K inhibitor, which exhibited a strong inhibitory activity especially against PI3K; (IC(50)=0.014 uM). In human tumor cell lines with PI3K pathway activation, CH5132799 showed potent antiproliferative activity. CH5132799 is orally available and showed significant antitumor activity in PI3K pathway-activated human cancer xenograft models in mice. Synonyms: CH5132799; CH-5132799; CH 5132799; PA-799; PA799; PA-799. CAS No. 1007207-67-1. Molecular formula: C15H19N7O3S. Mole weight: 377.423. | |
| CH5137291 | CH5137291 is a potent androgen receptor (AR) pure antagonist which did not produce the agonist metabolite with AR nuclear translocation-inhibiting activity. It inhibits the growth of castration-resistant prostate cancer cells. It offers a novel therapeutic approach against major types of castration-resistant prostate cancers. Uses: Ch5137291 offers a novel therapeutic approach against major types of castration-resistant prostate cancers. Synonyms: CH-5137291; CH 5137291;CH5137291; UNII-A5ZX7J376H; A5ZX7J376H; CHEMBL1290098. 6-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)pyridine-2-sulfonamide. Grades: >98 %. CAS No. 1043446-39-4. Molecular formula: C18H14F3N5O3S2. Mole weight: 469.46. | |
| CH5138303 | CH5138303 is a novel and potent Hsp90 inhibitor. CH5138303 showed high binding affinity for N-terminal Hsp90α (Kd = 0.52 nM) and strong in vitro cell growth inhibition against human cancer cell lines (HCT116 IC50=0.098 μM, NCI-N87 IC50=0.066 μM) and also displayed high oral bioavailability in mice (F = 44.0%) and potent antitumor efficacy in a human NCI-N87 gastric cancer xenograft model (tumor growth inhibition=136%). Synonyms: CH-5138303; CH 5138303. Grades: >98%. CAS No. 959763-06-5. Molecular formula: C19H18ClN5O2S. Mole weight: 415.90. | |
| CH5164840 | CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity against NSCLC cell lines and xenograft models. CH5164840 has potent antitumor activity and is highly effective in combination with erlotinib against NSCLC tumors with EGFR overexpression and mutations. Synonyms: CH5164840; CH-5164840; CH 5164840. Grades: 98%. CAS No. 1052645-73-4. Molecular formula: C19H23N5O2S. Mole weight: 385.49. | |
| CH5424802 Hydrochloride | CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Synonyms: Alectinib Hydrochloride; AF-802 Hydrochloride; CH-5424802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; AF 802 Hydrochloride; CH 5424802 Hydrochloride; RG 7853 Hydrochloride; RO 5424802 Hydrochloride; AF802 Hydrochloride; CH5424802 Hydrochloride; RG7853 Hydrochloride; RO5424802 Hydrochloride. Grades: >98%. CAS No. 1256589-74-8. Molecular formula: C30H35ClN4O2. Mole weight: 519.08. | |
| CH 5450 | Z-Ile-Glu-Pro-Phe-Ome is a peptide inhibitor of human heart chymase which is a chymotrypsin-like enzyme that converts angiotensin I to angiotensin II. Synonyms: ZIEPF-Ome; N-benzyloxycarbonyl-L-isoleucyl-L-alpha-glutamyl-L-prolyl-L-phenylalanine methyl ester; Cbz-Ile-Glu-Pro-Phe-OMe; CH5450; CH-5450. Grades: ≥95%. CAS No. 252557-97-4. Molecular formula: C34H44N4O9. Mole weight: 652.73. | |
| Ch 55 | Ch 55. Group: Biochemicals. Grades: Purified. CAS No. 110368-33-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CH 55 | CH 55 is an impurity of Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: Ch55; Ch-55; Ch 55. 4-[(1E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]benzoic Acid; (E)-4-[3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]-benzoic Acid; Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-. Grades: ≥98% by HPLC. CAS No. 110368-33-7. Molecular formula: C24H28O3. Mole weight: 364.48. | |
| CH7057288 | CH7057288 is a potent and selective TRK inhibitor. CH7057288 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095616-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107362. | |
| CH7057288 | CH7057288 is a selective TRK inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CH7057288; CH-7057288; CH 7057288. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2095616-82-1. Molecular formula: C32H31N3O5S. Mole weight: 569.68. Purity: >98%. IUPACName: N-(tert-butyl)-2-((6,6-dimethyl-8-(methylsulfonamido)-11-oxo-6,11-dihydronaphtho[2,3-b]benzofuran-3-yl)ethynyl)-6-methylisonicotinamide. Canonical SMILES: CS(NC1=CC=C2C(C(C)(C)C(OC3=CC(C#CC4=NC(C)=CC(C(NC(C)(C)C)=O)=C4)=CC=C35)=C5C2=O)=C1)(=O)=O. Product ID: ACM2095616821. Alfa Chemistry ISO 9001:2015 Certified. | |
| CH7057288 | CH7057288 is a selective TRK inhibitor that may be useful in inhibiting TRK fusion-positive cancer cell growth with IC50 values of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB, and TRKC respectively. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer. Synonyms: N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide; HY-107362; CS-0028214; RCH. CAS No. 2095616-82-1. Molecular formula: C32H31N3O5S. Mole weight: 569.67. | |
| ChaC1 | ChaC1 is isolated from Chassalia chartacea. It plays a role on mammalian cells and cancer cells. | |
| ChaC10 | ChaC10 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on cancer cells. | |
| ChaC11 | ChaC11 is isolated from Chassalia chartacea. It is against Escherichia coli. | |
| ChaC2 | ChaC2 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on cancer cells. | |
| ChaC4 | ChaC4 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on cancer cells. | |
| ChaC7 | ChaC7 is isolated from Chassalia chartacea (or Chassalia curviflora). It plays a role on Gram-negative bacteria, mammalian cells and cancer cells. | |
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