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| Product | Description | |
|---|---|---|
| CGP 23996 | CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography. Uses: Autoradiography. Synonyms: CGP 23996; CGP23996; CGP-23996. BDBM82467; 2-Deamino-L-Abu(1)-L-Lys-L-Asp(NH2)-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Tyr-L-Thr-L-Ser-L-Abu(1)-OH;(14R,20S,23R,26R,29R,32R)-2,17-bis(4-aminobutyl)-5-(2-amino-2-oxoethyl)-8,11-dibenzyl-20,26-bis[(1S)-1-hydroxyethyl]-29-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazacyclooctatriacontane-32-carboxylic acid. Grades: 98%. CAS No. 86170-12-9. Molecular formula: C73H99N15O18. Mole weight: 1474.66. |  |
| Cgp 29030A | This molecular is a piperazine derivative and its Pharmacological activity probablely is inhibition on nociceptive dorsal horn neurons that processed input from high-threshold mechanosensitive receptors in the skin and deep somatic tissues.It may be used to treat painful disorders which are complicated by increased motor. activity. Uses: Treat painful disorders. Synonyms: Cgp 29030A; Cgp29030A; Cgp-29030A. 1-p-chlorophenethyl-4-(3,5-dimethoxybenzoyl)piperazine hydrochloride. Grades: 98%. CAS No. 113240-27-0. Molecular formula: C21H26Cl2N2O3. Mole weight: 425.35. | |
| Cgp 29287 | Cgp 29287 is a renin inhibitor with a prolonged duration of action. Synonyms: CGP-29287; Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Nepsilon-Boc-Lys methyl ester. Grades: 95%. CAS No. 93287-54-8. Molecular formula: C72H110N20O15. Mole weight: 1495.77. | |
| Cgp 31358 | CGP 31358 is a compound that can bind to a site on the N-methyl-D-aspartate (NMDA) receptor which is coupled to both the transmitter recognition site and the channel domain.It can be a tool for researching the molecular pharmacology of this receptor-channel complex. Uses: A tool for researching the molecular pharmacology of receptor-channel complex. Synonyms: Cgp 31358; Cgp-31358; Cgp31358; 1-(4-(1-(4-chlorophenyl)-1-methylethyl)-2-methoxyphenyl)-1H-1,2,4-Triazole-3-carboxamide. Grades: 98%. CAS No. 125652-47-3. Molecular formula: C19H19ClN4O2. Mole weight: 370.83. | |
| Cgp-33304 | Cgp-33304 is a dual phospholipase A2 inhibiting agent and leukotriene receptor antagonists. It may prevent hypoxia secondary to leukotriene induced bronchoconstriction in shock states. It has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Uses: Cgp-33304 has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Synonyms: Cgp 33304; Cgp33304; Cgp-33304; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-bromo-2-methylphenyl)-, monosodium salt;CGP33304;N-(3-(3-(4-Acetyl-3-hydroxy-2-n-propylphenoxy)propoxy)-4-bromo-6-methylphenyl)-1H-tetrazole-5-carboxamide sodium;Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-bromo-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grades: >98%. CAS No. 111130-14-4. Molecular formula: C23H25BrN5NaO5. Mole weight: 554.38. | |
| CGP 3466B maleate | CGP 3466B maleate. Group: Biochemicals. Grades: Purified. CAS No. 200189-97-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CGP 3466B maleate | CGP 3466B maleate, a potent anti-apoptotic drug, is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. CGP 3466B maleate was tested in clinical trials for its ability to help treat Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) but the clinical trials have been terminated due to lack of benefit. Synonyms: N-(benzo[b][1]benzoxepin-5-ylmethyl)-N-methylprop-2-yn-1-amine;but-2-enedioic acid; Omigapil maleate; CGP 3466B; CGP-3466B; CGP3466B; TCH-346; TCH 346; TCH346; Omigapil maleate. Grades: >99 %. CAS No. 200189-97-5. Molecular formula: C23H21NO5. Mole weight: 391.42. | |
| CGP35348 | CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC 50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only [1]. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123690-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103530. |  |
| CGP 35348 | CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Synonyms: CGP35348; CGP-35348; (3-Aminopropyl) (diethoxymethyl)phosphinic acid. CAS No. 123690-79-9. Molecular formula: C8H20NO4P. Mole weight: 225.22. | |
| CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348) | A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cgp-35949 | Cgp-35949 is an LTD4 antagonist which has phospholipase inhibitory activity. It represents a new approach to the treatment of asthma. Uses: Cgp-35949 represents a new approach to the treatment of asthma. Synonyms: Cgp 35949; Cgp-35949; Cgp35949; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-chloro-2-methylphenyl)-, monosodium salt;CGP35949;N-(5-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)-1H-tetrazole-5-carboxamide monosodium salt;Sodium N-[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]-4-chloro-2-methylphenyl]-1,2,3-triaza-4-azanidacyclopenta-2,5-diene-5-carboxamide;Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grades: >98%. CAS No. 111130-13-3. Molecular formula: C23H25ClN5NaO5. Mole weight: 509.92. | |
| CGP 36216 | CGP 36216 hydrochloride is a selective GABAB antagonist that is active to presynaptic receptors but inactive to postsynaptic receptors. Synonyms: CGP 36216 hydrochloride; CGP36216 hydrochloride; CGP-36216 hydrochloride; (3-Aminopropyl)ethylphosphinic acid hydrochloride. Grades: ≥99% by HPLC. CAS No. 123691-29-2. Molecular formula: C5H14NO2P. Mole weight: 151.14. | |
| CGP 36216 hydrochloride | CGP 36216 is a selective GABA antagonist with IC50 of 43 μM, which is active at the presynaptic but not postsynaptic. Synonyms: CGP 36216. Grades: ≥98%. CAS No. 1781834-71-6. Molecular formula: C5H14NO2P·HCl. Mole weight: 187.6. | |
| CGP 36216 hydrochloride | CGP 36216 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 123691-29-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 37157 | CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 can be used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. Synonyms: Cgp 37157; Cgp-37157; Cgp37157. 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one. Grades: 98%. CAS No. 75450-34-9. Molecular formula: C15H11Cl2NOS. Mole weight: 289.78. | |
| CGP 37157 | CGP 37157. Group: Biochemicals. Grades: Purified. CAS No. 75450-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 37849 | CGP 37849. Group: Biochemicals. Grades: Purified. CAS No. 127910-31-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 37849 | CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). CGP 37849 exhibits an anticonvulsant effect following oral administration in vivo. Synonyms: CGP37849; CGP 37849; CGP-37849; (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid. Grades: ≥99% by HPLC. CAS No. 127910-31-0. Molecular formula: C6H12NO5P. Mole weight: 209.14. | |
| CGP 37849 | CGP 37849 is a potent, competitive and orally active N-methyl-D-aspartate (NMDA) receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127910-31-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-107702. | |
| CGP 37849 ((E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic Acid) | A highly potent competitive antagonist selective fornMDA receptors (Ki = 35nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 127910-31-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cgp 38560 | Cgp 38560 is a potent renin inhibitor and it can induce a dose-dependent decrease in angiotensin II and plasma renin activity and a long-lasting and dose-dependent rise in active renin. Although reduction of plasma renin activity to unmeasurable levels, the doses used did not reduce plasma angiotensin II maximally. Synonyms: Cgp 38560; Cgp38560; Cgp-38560. (R)-N-(2-(((1,1-dimethylethyl)sulfonyl)methyl)-1-oxo-3-phenylpropyl)-L-histidyl-3-cyclohexyl-L-alanyl-N-butyl-L-Valinamide monomethanesulfonate. Grades: 98%. CAS No. 122088-76-0. Molecular formula: C39H64N6O9S2. Mole weight: 825.09. | |
| CGP 39551 | CGP 39551. Group: Biochemicals. Grades: Purified. CAS No. 127910-32-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 39551 | Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding in rat brain. CGP 39551 produces excitatory effects and causes psychotomimetic effects in humans. Treatment for Craniocerebral trauma, Epilepsy and Stroke was discontinued. Uses: Craniocerebral trauma, epilepsy and stroke. Synonyms: Cgp 39551; Cgp39551; Cgp-39551; (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester;CGP 39551;(E)-(-)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester. Grades: 98%. CAS No. 127910-32-1. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| Cgp 39653 | Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affinity. It is currently the ligand of choice for labeling the NMDA receptor. Uses: The ligand of choice for labeling the nmda receptor. Synonyms: Cgp 39653; Cgp-39653; Cgp-39653; (R,Z)-2-amino-4-(phosphonomethyl)hept-3-enoic acid. Grades: 98%. CAS No. 132472-31-2. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| CGP 42112 | CGP 42112. Group: Biochemicals. Grades: Purified. CAS No. 127060-75-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| CGP-42112A | CGP-42112A, an angiotensin AT2 receptor agonist which could probably lead to the inhibition of ATPase and contraction of aortic rings in rabbit. Uses: Cgp-42112a is an angiotensin at2 receptor agonist which could probably lead to the inhibition of atpase and contraction of aortic rings in rabbit. Synonyms: Cgp 42112A; Cgp-42112A; Cgp42112A; Cgp 42112B; Cgp-42112B; Cgp42112B; CGP-42112; CGP 42112; CGP42112. Grades: ≥95%. CAS No. 127060-75-7. Molecular formula: C52H69N13O11. Mole weight: 1052.2. | |
| CGP-42454A | CGP-42454A is a epimer of Benazepril ,an approved drug using for the treatment of Hypertension. Synonyms: CGP-42454A; CGP 42454A; CGP42454A; UNII-15B0UK1949;2-((R)-3-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid. Grades: 98%. CAS No. 131064-74-9. Molecular formula: C24H28N2O5. Mole weight: 424.49. | |
| CGP 43182 | CGP 43182, a dioxaspiro compound, has been found to a IIA sPLA2 inhibitor that could have potential anti-inflammatory effect and also in influencing the synergistic effect brought by pro-inflammatory genes. Synonyms: Cgp 43182; Cgp-43182; Cgp43182. N-(2,3-Dichlorophenyl)-2-hydroxy-4-oxo-1,5-dioxaspiro(5.5)undec-2-ene-3-carboxamide; N-(2,3-dichlorophenyl)-2-hydroxy-4-oxo-1,5-dioxaspiro[5.5]undec-2-ene-3-carboxamide; AC1L2SHN; DTXSID00164535. Grades: 98%. CAS No. 150379-37-6. Molecular formula: C16H15Cl2NO5. Mole weight: 372.20. | |
| CGP 43487 | CGP 43487 has been found to be a NMDA receptor antagonist and was once studied about its influenment of dopaminergic function as a supplement in the treatment of Parkinson's disease. Synonyms: Cgp 43487; Cgp43487; Cgp-43487; [(E,4R)-4-amino-5-ethoxy-2-methyl-5-oxopent-2-enyl]phosphonic acid. Grades: 98%. CAS No. 146388-56-9. Molecular formula: C8H16NO5P. Mole weight: 237.19. | |
| Cgp 43902A | Cgp 43902A is a bio-active molecular, but no detailed information has been published yet. Synonyms: Cgp 43902A; Cgp43902A; Cgp-43902A. ethyl 2-[(4Z)-5-(hydroxymethyl)-2-methyl-3-oxo-4-[(2-pyridin-2-ylhydrazinyl)methylidene]pyridin-1-ium-1-yl]acetate;bromide. Grades: 98%. CAS No. 124076-31-9. Molecular formula: C17H21BrN4O4. Mole weight: 425.28. | |
| Cgp 45688 | Cgp 45688 is an non-steroidal aromatase inhibitor originated byNovartis. It has anti-tumor effects, but no development for treatment of cancer was reported. Uses: Cancer. Synonyms: Cgp 45688; Cgp45688; Cgp-45688. 4,4'-(2H-tetrazol-2-ylmethylene)bis-Benzonitrile. Grades: 98%. CAS No. 134520-88-0. Molecular formula: C16H10N6. Mole weight: 286.30. | |
| CGP 46381 | CGP 46381 is a selective GABAB receptor antagonist (IC50 = 4.9 μM). Synonyms: (3-Aminopropyl) (cyclohexylmethyl)phosphinic Acid; P-(3-Aminopropyl)-P-(cyclohexylmethyl)phosphinic Acid. CAS No. 123691-14-5. Molecular formula: C10H22NO2P. Mole weight: 219.26. | |
| CGP 47072 | CGP 47072, a bisphosphonate derivative, has been found to be a calcium regulator and was once studied in the treatment of osteoporosis. Synonyms: Cgp 47072; Cgp47072; Cgp-47072.CHEMBL101886; AC1L4IPT; SCHEMBL7164644; [1-hydroxy-3-[methyl(3-phenoxypropyl)amino]-1-phosphonopropyl]phosphonic acid. Grades: 98%. CAS No. 158859-42-8. Molecular formula: C13H23NO8P2. Mole weight: 383.27. | |
| Cgp 47645 | Cgp 47645 is non-steroidal aromatase inhibitor with anti-tumor and endocrine effects. It is orally active. Uses: Anti-tumor. Synonyms: Cgp 47645; Cgp47645; Cgp-47645; Leflutrozole; UNII-RCX0IE6EJZ;4,4'-(fluoro-1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile. Grades: 98%. CAS No. 143030-47-1. Molecular formula: C17H10FN5. Mole weight: 303.30. | |
| CGP 48369 | Cgp 48369 is a nonpeptide a angiotensin type 1 receptor antagonist originated by Novartis. Treatmenf for for Hypertension in Switzerland was discontinued in 1995. Uses: Hypertension. Synonyms: Cgp 48369; Cgp48369; Cgp-48369. 5-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2,6-dibutylpyrimidin-4(1H)-one. Grades: 98%. CAS No. 135689-23-5. Molecular formula: C26H30N6O. Mole weight: 442.56. | |
| CGP52411 | CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor receptor (EGFR). It is also inhibits and reverses the formation of Aβ42 fibers associated with Alzheimer's disease. It may offer therapeutic agents for the treatment of hyperproliferative diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGP52411; CGP 52411; CGP-52411; DAPH. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.36. Purity: >98%. IUPACName: 5,6-bis(phenylamino)isoindoline-1,3-dione. Canonical SMILES: O=C1NC(C2=CC(NC3=CC=CC=C3)=C(C=C21)NC4=CC=CC=C4)=O. Product ID: ACM145915588-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,5-dianilinophthalimide. |  |
| CGP 52411 | CGP 52411. Group: Biochemicals. Grades: Purified. CAS No. 145915-58-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 52411 | CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 μM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP 52411; CGP52411; CGP-52411; 5,6-dianilinoisoindole-1,3-dione; 406-050-3; Z13D008FZ2; 4,5-dianilinophthalimide; DAPH; Cgp 52411; 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione; 145915-58-8; Cgp-52411; UNII-Z13D008FZ2; CHEMBL268868; 5,6-dianilino-1h-isoindole-1,3(2h)-dione; CHEBI:53110; Z13D008FZ2; AC1Q6JME; DAPH-1; SCHEMBL11017; 4,5-Bis(anilino)phthalimide; D3943_SIGMA; 4,5-bis-(anilino)phthalimide; AC1L1C19; ZINC6094; DTXSID4040393; CTK8D4606; AAALVYBICLMAMA-UHFFFAOYSA-N; BCPP000288; HMS3260P13; 5,6-dianilinoisoindole-1,3-dione; Tox21_500236; ABP000886; AR-1G6110; BDBM50040929; MFCD00236442; AKOS024457581; BCP9000511; CCG-221540; LP00236; CGP 52411/CGP52411; NCGC00093700-01; NCGC00093700-02; NCGC00093700-03; NCGC00093700-04; NCGC00093700-05; NCGC00260921-01; AK393267; HE062397; HE312151; 5,6-Bis-phenylamino-isoindole-1,3-dione; 5,6-Bis(phenylamino)isoindoline-1,3-dione; J587.895K; 1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-; BRD-K13087974-001-01-7; CGP 52411|DAPH|5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.35. | |
| CGP52421 | Cas No. 179237-49-1. | |
| CGP52432 | CGP52432 is a GABA B receptor antagonist, with an IC 50 of 85 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 139667-74-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103531. | |
| CGP 52432 | CGP52432 is a potent and selective GABAB receptor antagonist with IC50 value of 85 nM. Synonyms: Cgp 52432; Cgp52432; Cgp52432; 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid. Grades: >98 %. CAS No. 139667-74-6. Molecular formula: C15H24Cl2NO4P. Mole weight: 384.24. | |
| CGP-53153 | CGP-53153 is a steroidal inhibitor of 5 alpha reductase is a steroidal which effects the conversion of testosterone (T) to 5α-dihydrotestosterone (DHT). In vitro, CGP 53153 competitively inhibited rat microsomal 5α-reductase from prostate by 50% (ICs0) at a concentration of 36 nM compared to the reference compound finasteride which inhibited 5α-reductase with an ICs0 of 11 nM in the same system. In vivo, inhibition of 5α-reductase activity was characterized in three different test systems. Synonyms: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-(2-cyanopropan-2-yl)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide; wt1-ricin a; SCHEMBL8823373; CGP 53153; CGP-53153; CGP53153. CAS No. 149281-19-6. Molecular formula: C23H33N3O2. Mole weight: 383.53. | |
| CGP 53353 | CGP 53353. Group: Biochemicals. Grades: Purified. CAS No. 145915-60-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP 53353 | CGP 53353, also called DAPH 2, highly selectively inhibits procarcinogenic protein kinase C-βII (PKCβII) ,and it is also an inhibitor of prionogenic Sup35 fibrillization (IC50 ~ 3.4 μM). It inhibits de novo Aβ42 assembly in vitro. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP53353; CGP 53353; CGP-53353. 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; DAPH 2; CGP-53353; 145915-60-2; DAPH-7; PKCbetaII/EGFR Inhibitor; CHEMBL7939; 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione; 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE; IN1137; 4,5-bis(4-Fluoroanilino)-phthalimide; CGP 53 353; CG53353; 4,5-Bis(4-fluoroanilino)phthalimide; 4,5-Bis[4-fluoroanilino]phthalimide; PKCbII/EGFR Inhibitor; AC1O8KXF; DAPH-2; MolMap_000016; C7866_SIGMA; SCHEMBL230492; GTPL5163; CTK8E9235; RONQPWQYDRPRGG-UHFFFAOYSA-N; HMS3229K07; HMS3269E05; ZINC600430; CGP53353; BDBM50040930; CGP 53353; DNC003638; MFCD00938569; AKOS015911570; CCG-206784; NCGC00159569-01; NCGC00159569-02; AK394840; HE005407; HE312152; ZB014534; DB-042814; FT-0643387; 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione; 5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione; BRD-K32292990-001-01-0; I14-37922; 5,6-bis[(4-fluorophenyl)amino]-2,3-dihydro-1H-isoindole-1,3-dione; CGP 53353|5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione. CAS No. 145915-60-2. Molecular formula: C20H13F2N3O2. Mole weight: 365.34. | |
| CGP 53820 | CGP 53820 has been found to be a HIV-1 Protease pseudosymmetric inhibitor that could probably be effective in the treatment of HIV infections. Synonyms: Cgp 53820; Cgp-53820; Cgp53820; (2S)-2-acetamido-N-[(2S,3S)-4-[[[(2S)-2-acetamido-3-methylbutanoyl]amino]-(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-3-methylbutanamide. Grades: 98%. CAS No. 149267-24-3. Molecular formula: C31H51N5O5. Mole weight: 573.78. | |
| CGP 54626 hydrochloride | CGP 54626 (hydrochloride) is a selective antagonist of GABA B receptor with an IC 50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABA B receptors in neurological signaling [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149184-21-4. Pack Sizes: 1 mg. Product ID: HY-101378. | |
| CGP 54626 hydrochloride | The hydrochloride salt form of CGP 54626, a dichloropheny derivative, has been found to be a GABAB receptor antagonist that could probably be effective as an analgesic agent. IC50: 4 nM. Synonyms: CGP 54626 hydrochloride; CGP54626 hydrochloride; CGP-54626 hydrochloride; CGP 54626 HYDROCHLORIDE;[S-(R*,R*)]-[3-[[1-(3,4-DICHLOROPHENYL)ETHYL]AMINO]-2-HYDROXYPROPYL](CYCLOHEXYLMETHYL) PHOSPHINIC ACID HYDROCHLORIDE;(S-(R*,R*))-(3-((1-(3,4-Dichlorophenyl)ethyl)amino)-2-hydroxypropyl)-([3.4-3H]-cyclohexylmethyl)phosphinicacid;[3. Grades: 98%. CAS No. 149184-21-4. Molecular formula: C18H28Cl2NO3P.HCl. Mole weight: 410.31. | |
| CGP 55802A | CGP 55802A has been found to be a photoaffinity ligand that could be used to label NMDA receptor and have high selectivity to glutamate recognition site. Synonyms: Cgp-55802A; Cgp 55802A; (E)-2-Amino-10-((4-azido-2-hydroxy-3-iodobenzoyl)amino)-4-(phosphonomethyl)-3-decenoic acid monosodium salt; 152564-63-1; 2-Amino-10-((4-azido-2-hydroxy-3-iodobenzoyl)amino)-4-phosphonomethyl-dec-3-enoic acid sodium salt; 3-Decenoi. Grades: 98%. CAS No. 152564-63-1. Molecular formula: C18H24IN5NaO7P. Mole weight: 603.29. | |
| CGP 55845 hydrochloride | CGP 55845 hydrochloride is a potent and selective GABAB receptor antagonist (IC50 = 5 nM), which prevents agonist binding (pKi = 8.35) and inhibits release of GABA and glutamate (pEC50 = 8.08 and 7.85, respectively). Synonyms: CGP 55845 HCl; CGP 55845HCl; CGP 55845; CGP55845; CGP-55845; (2S)-3-[[ (1S)-1- (3, 4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl] (phenylmethyl)phosphinic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 149184-22-5. Molecular formula: C18H22Cl2NO3P.HCl. Mole weight: 438.71. | |
| CGP55845 hydrochloride | CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM. CGP55845 hydrochloride can be used for neurological research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149184-22-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103516. | |
| CGP 57380 | CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. Synonyms: CGP-57380; CGP57380; CGP 57380. Grades: >98%. CAS No. 522629-08-9. Molecular formula: C11H9FN6. Mole weight: 244.23. | |
| CGP 57380 | CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC 50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 522629-08-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10520. | |
| CGP 57380 | CGP 57380. Group: Biochemicals. Grades: Purified. CAS No. 522629-08-9. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 57813 | CGP 57813 has been found to be a HIV-1 protease inhibitor that has been once developed by Novartis. Synonyms: Cgp 57813; Cgp-57813; Cgp57813; Carbamic acid, (2-hydroxy-4- ( (4-methoxyphenyl) methyl) -5- ( (2-methyl-1- ( ( (2- (4-morpholinyl) -2-oxo-1- (phenylmethyl) ethyl) amino) carbonyl) propyl) amino) -5-oxo-1- (phenylmethyl) pentyl) -, 1,1-dimethylethyl ester, (1S-(1R*,2R*,4S*,5(. Grades: 98%. CAS No. 150608-41-6. Molecular formula: C43H58N4O8. Mole weight: 758.94. | |
| CGP-59326 | CGP-59326, a pyrrolopyrimidine derivative, has been found to be an EGFR antagonist and could used in antineoplastic studies. Synonyms: CGP-59326; CGP 59326; CGP59326; CHEMBL306081; 1H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-; 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-. Grades: 98%. CAS No. 173458-56-5. Molecular formula: C14H13ClN4. Mole weight: 272.73. | |
| CGP60474 | CGP60474 is a promising inhibitor of PKC with a high degree of selectivity versus other serine/threonine and tyrosine kinases and show competitive kinetics relative to ATP. Synonyms: CGP-60474; CGP 60474. Grades: >98%. CAS No. 164658-13-3. Molecular formula: C18H18ClN5O. Mole weight: 355.82. | |
| CGP-62198A | CGP-62198A, a piperidine derivative, could probably be useful in some biological studies. Synonyms: CGP-62198A; CGP 62198A; CGP62198A; UNII-WXF63HI1WD; WXF63HI1WD; SCHEMBL6042796. Benzamide, N-((2S,4S,5S,7S)-7-(((2-(4-acetyl-1-piperidinyl)ethyl)amino)carbonyl)-4-amino-5-hydroxy-8-methyl-2-(1-methylethyl)nonyl)-2-(4-methoxybutoxy)-. Grades: 98%. CAS No. 180183-51-1. Molecular formula: C35H60N4O6. Mole weight: 632.89. | |
| Cgp 6809 | Cgp 6809 is a new methylnitrosoureido-sugar derivative. It is active against a broad spectrum of transplantable tumours in mice and rats. But Phase I clinical trials for the treatment of solid tumor were discontinued. Uses: Cancer. Synonyms: Cgp 6809; Cgp6809; Cgp-6809; ethyl-6-deoxy-3,5-di-O-methyl-6-(3-methyl-3-nitrosoureido)glucofuranoside. Grades: 98%. CAS No. 84069-38-5. Molecular formula: C12H23N3O7. Mole weight: 321.33. | |
| CGP 71683 hydrochloride | CGP 71683 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 192322-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 71683 hydrochloride | CGP 71683 hydrochloride is a highly selective non-peptide antagonist of the NPY Y(5) receptor (IC50= 1.4 nM) with > 1000-fold selectivity over Y1 (IC50= 2765 nM), Y2 (IC50= 7187 nM) and Y4 (IC50= 5637 nM) receptors. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats. Synonyms: N- [ [4- [ [ (4-aminoquinazolin-2-yl) amino] methyl] cyclohexyl] methyl] naphthalene-1-sulfonamide; hydrochloride; CGP 71683 A; CGP-71683A; CGP 71683 hydrochloride; CGP71683 hydrochloride; CGP-71683 hydrochloride. Grades: >99 %. CAS No. 192322-50-2. Molecular formula: C26H29N5O2S.HCl. Mole weight: 512.07. | |
| CGP71683 hydrochloride | CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a K i of 1.3 nM, and shows no obvious activity at Y1 receptor ( K i , >4000 nM) and Y2 receptor ( K i , 200 nM) in cell membranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP71683A. CAS No. 192322-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107723. | |
| CGP74514A | CGP74514A is a cell permeable Cdk inhibitor selective for Cyclin-dependent kinase-1 (Cdk1) (IC50=25nM). CGP74514A was also reported also to affect the activities of other kinases including PKCα (IC50=6.1μM), PKA (IC50=125μM) and EGFR (IC50>10μM), but only at much higher concentrations. Synonyms: 2-N-[(1R,2S)-2-aminocyclohexyl]-6-N-(3-chlorophenyl)-9-ethylpurine-2,6-diamine; CGP 74514A; 481724-82-7 (CGP74514A HCl salt); CGP-74514A; CGP74514A; N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine. Grades: >98%. CAS No. 190653-73-7. Molecular formula: C19H24ClN7. Mole weight: 385.9. | |
| CGP 74514 dihydrochloride | CGP 74514 Dihydrochloride is a potent cdk1 inhibitor with IC50 of 25 nM. It can reduce Akt phosphorylation and increase mitochondrial damage in leukemia cells. Synonyms: CGP 74514. Grades: ≥98%. Molecular formula: C19H24ClN7·2HCl. Mole weight: 458.82. | |
| CGP-75254A | CGP-75254A, a novel oral iron chelator, across Caco-2 cells in an attempt to model intestinal epithelial cell permeability in man. Studies predicted that absorption of CGP-75254A is likely to be virtually complete at pH values between 5.5 and 7.0. However, at pH 8.0 permeability is predicted as negligible. Synonyms: sodium;2-[2-[(2-ethoxy-2-oxoethyl)-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetate; CGP-75254A; CGP 75254A; CGP75254A; UNII-94KC20I6YX; 199485-27-3 (CGP-75254A Free Acid). Grades: >98%. CAS No. 199485-26-2. Molecular formula: C22H27N2NaO6. Mole weight: 438.45. | |
| CGP-75355 | CGP-75355 is an HIV Protease inhibitor (EC50= 0.7 nM). Uses: Hiv protease inhibitors. Synonyms: CGP-75355; CGP 75355; CGP75355; UNII-4ZE7DBE752; methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-phenylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; 232632, BMS; 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester; atazanavir; atazanavir sulfate; BMS 232632; BMS 232632 05; BMS-232632; BMS-232632-05; BMS232632; BMS23263205. Grades: >98%. CAS No. 191594-64-6. Molecular formula: C39H53N5O7. Mole weight: 703.87. | |
| CGP 76030 | CGP76030 is a ual-specific Src and Abl kinase inhibitor, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases. Uses: Ual-specific src and abl kinase inhibitor. Synonyms: CGP-76030; CGP76030; CGP76030; CGP-076030. 7-(4-(2-((2-methoxyethyl)amino)ethoxy)phenyl)-5-(3-methoxyphenyl)-7H-Pyrrolo(2,3-d)pyrimidin-4-amine. Grades: ≥98%. CAS No. 497152-38-2. Molecular formula: C24H27N5O3. Mole weight: 433.5. | |
| CGP77675 | CGP77675 is an orally active and potent inhibitor of Src family kinases. CGP77675 inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src ( IC 50 s of 5-20 and 40 nM, respectively), and also inhibits Src, EGFR, KDR, v-Abl, and Lck with IC 50 s of 5-20, 40, 20, 150, 1000, 310, and 290 nM, respectively. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 234772-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W062835. | |
| CGP 77675 | CGP 77675 is a potent Src kinase inhibitor. It can be used to maintain mouse embryonic stem cell (mESC) in combination with CHIR99021. Uses: Protein kinase inhibitors. Synonyms: CGP-77675; 1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol. Grades: >98%. CAS No. 234772-64-6. Molecular formula: C26H29N5O2. Mole weight: 443.55. | |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor , with an IC 50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC 50 in the low nM range (26.3 nM). Anticonvulsant activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135278-54-4. Pack Sizes: 1 mg. Product ID: HY-107701. | |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a potent and selective NMDA antagonist with > 500-fold selectivity over kainate and AMPA receptors (IC50 = 2.7 and 3 μM, respectively). CGP 78608 exhibits an anticonvulsant effect in vivo following systemic administration. Synonyms: CGP78608 hydrochloride; CGP-78608 hydrochloride; [ (1S) -1-[[ (7-Bromo-1, 2, 3, 4-tetrahydro-2, 3-dioxo-5-quinoxalinyl) methyl]amino]ethyl]phosphonic acid hydrochloride; Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochloride (1:1); (S)-(1-(((7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1135278-54-4. Molecular formula: C11H13BrN3O5P.HCl. Mole weight: 414.58. | |
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