A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grade: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41.
c-Met Kinase Inhibitor III
The c-Met Kinase Inhibitor III controls the biological activity of c-Met. Group: Fluorescence/luminescence spectroscopy.
c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
c-Met/RON Dual Kinase Inhibitor - CAS 913376-84-8
The c-Met/RON Dual Kinase Inhibitor, also referenced under CAS 913376-84-8, controls the biological activity of c-Met/RON. Group: Fluorescence/luminescence spectroscopy.
CMF019
CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents[1]. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1586787-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103080.
CMG-101
CMG-101 is a novel selective inhibitor of mTORC1/2. Studies suggest that CMG-101 would overcome the drug resistance of mTORC1 inhibitor through the activation of signal transduction pathways via mTORC2. CMG-101 is promisingly to be a antitumor drug. Uses: Potential antitumor drug. Synonyms: CMG101; CMG 101.
CM-H2DCFDA
CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 850013-49-9. Pack Sizes: 50 ?g. Product ID: HY-D1713.
CMHPG
CMHPG.
CMI-392
CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM). Uses: Lipoxygenase inhibitors. Synonyms: 3-[[2-[2-(4-chlorophenyl)sulfanylethoxy]-3-methoxy-5-[(2S,5S)-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]phenyl]methyl]-1-hydroxy-1-methylurea; 2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran; CMI 392; CMI-392. CAS No. 205654-37-1. Molecular formula: C31H37ClN2O8S. Mole weight: 633.15.
CMI-977
CMI-977, an oxolan compound, has been found to be a 5-Lipoxygenases inhibitor and was once studied as an antiasthmatic agent. Synonyms: CMI-977; CMI 977; CMI977; LPD-977; LPD 977; LPD977; MLN-977; MLN977; MLN 977; 1-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]oxolan-2-yl]but-3-ynyl]-1-hydroxyurea. Grade: 98%. CAS No. 175212-04-1. Molecular formula: C16H19FN2O4. Mole weight: 322.34.
CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grade: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82.
CMK
CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. Uses: Scientific research. Group: Signaling pathways. CAS No. 821794-90-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101.
CMK-3
CMK-3. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-216. Alfa Chemistry ISO 9001:2015 Certified. Categories: methane, CM-32 armoured vehicle.
CMK-8
CMK-8. Uses: Designed for use in research and industrial production. Product Category: Mesoporous Carbon and Carbon Nanomaterials. CAS No. 7440-44-0. Product ID: ACM7440440-161. Alfa Chemistry ISO 9001:2015 Certified. Categories: CMA 8.
CMLD012072
CMLD012072, an amidino-rocaglates, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with strong antitumor activity. It can induce RNA to clamp eIF4A1 and eIF4A2. Synonyms: Methyl (3aR,4R,5S,5aR,10bR)-2-cyclopropyl-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate; 1H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 2-cyclopropyl-3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-. Grade: ≥95%. CAS No. 2368900-33-6. Molecular formula: C32H32N2O7. Mole weight: 556.61.
CMLD012073
CMLD012073, an amidino-rocaglates and a potent eukaryotic initiation factor 4A (eIF4A) inhibitor, inhibits NIH/3T3 cells growth with an IC50 of 10 nM. It inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A). Synonyms: 3H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-; Methyl (3aR,4R,5S,5aR,10bR)-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate. Grade: ≥97%. CAS No. 2368900-32-5. Molecular formula: C30H30N2O7. Mole weight: 530.57.
CMLD-2 is an inhibitor of HuR-ARE interaction. CMLD-2 induces apoptosis and exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Synonyms: 5,7-dimethoxy-8-(1-(4-methoxyphenyl)-3-oxo-3-(pyrrolidin-1-yl)propyl)-4-phenyl-2H-chromen-2-one. Grade: 98%. CAS No. 958843-91-9. Molecular formula: C31H31NO6. Mole weight: 513.58.
CMLD-2
CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 958843-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-124828.
Cm-p1
Cm-p1 was found in marine snail Cenchritis muricatus. This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells.
CMP5
CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grade: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87.
CMP-5
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880813-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120137.
CMP-5
CMP5 is a potent, selective and specific inhibitor of PRMT5, but has no activity against PRMT1, PRMT4 and PRMT7 enzymes. CMP5 selectively blocks S2Me-H4R3 by inhibiting the activity of PRMT5 methyltransferase on histone preparations. It prevents epstein-barr virus (EBV)-driven B-lymphocyte transformation, but does not affect normal B cells. Synonyms: 1-(9-ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine; PRMT5-IN-5; N-[(9-ethyl-9H-carbazol-3-yl)methyl]-N-(2-pyridinylmethyl)amine; 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-. Grade: ≥98%. CAS No. 880813-42-3. Molecular formula: C21H21N3. Mole weight: 315.41.
CMP-5 2HCl
CMP-5 2HCl is a repellent. The EC100 of CMP-5 2HCl in vitro against H. contortus is 5 μM. Synonyms: 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-,hydrochloride (1:2). Grade: >98.0%. CAS No. 2309409-79-6. Molecular formula: C21H23Cl2N3. Mole weight: 388.34.
CMP8
CMP8 is a selective ligand for the estrogen receptor, which can bind to the ligand binding domain of the estrogen receptor. The IC50 values of CMP8 for mutant MGERα, MGRERα and wild-type hERα and hERβ are 29 nM, 41 nM, 1100 nM and 2200 nM, respectively. Grade: 98%. CAS No. 851107-28-3. Molecular formula: C33H34ClNO3. Mole weight: 528.1.
CMP-9-fluoresceinyl-NeuAc
CMP-9-fluoresceinyl-NeuAc, is shown to be a suitable donor substrate for sialyltransferase, which belongs to glycosyltransferase family 29. Synonyms: N-Acetyl-9-deoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-2-(hydrogen 5'-cytidylate) β-Neuraminic Acid; 5-(Acetylamino)-3,5,9-trideoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-D-glycero-β-D-galacto-2-Nonulopyranosonic Acid 2-(Hydrogen 5'-cytidylate); Spiro[isobenzofuran-1(3H),9'-[9H]xanthene] D-glycero-β-D-galacto-2-nonulopyranosonic acid Deriv. CAS No. 118720-35-7. Molecular formula: C41H43N6O20PS. Mole weight: 1002.85.
CMP-9-O-acetyl-N-acetylneuraminic acid
CMP-9-O-acetyl-N-acetylneuraminic acid is an indispensable compound, having multifarious utilities in an array of maladies, ranging from influenza to viral infections and autoimmune disorders. The distinctive attributes it possesses render it an imperative constituent for investigating sialic acid metabolism and glycoconjugate. Synonyms: CMP-9-O-Ac-Neu5Ac. Molecular formula: C22H33N4O16P. Mole weight: 640.49.
CMP-C9-Azido-Sialic Acid sodium
CMP-C9-Azido-Sialic Acid is a synthetic derivative belonging to the sialic acid family found in many types of glycoproteins and glycolipids. Grade: ≥85%. Molecular formula: C20H31N7NaO15P. Mole weight: 663.47.
CMP-CP
CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Cytidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 101536-15-6. Molecular formula: C10H17N3O10P2 (free acid). Mole weight: 401.2 (free acid).
CMPD-1
CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4.
CMPD-1
CMPD-1. Group: Biochemicals. Grades: Purified. CAS No. 41179-33-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CMPD101
CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKC? with IC50s of 3.1 ?M , 2.3 ?M, 1.4 ?M and 8.1 ?M, respectively. CMPD101 can be used for the study of heart failure[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865608-11-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103045.
CMPD101
CMPD101 is a novel, potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35 and 32 nM at GRK2 and GRK3 respectively). CMPD101 exhibits selectivity for GRK2/3 over GRK1/5 and reduces DAMGO-induced desensitization and internalization of μ-opioid receptors. CMPD101 has been shown to potentiate phosphatidylinositol 4,5-bisphosphate (PIP2) depletion and slow agonist-induced desensitization of protease-activated receptor 2 (PAR2). Uses: Designed for use in research and industrial production. Additional or Alternative Names: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.47. Purity: >98%. IUPACName: 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide. Canonical SMILES: O=C(NCC1=CC=CC=C1C(F)(F)F)C2=CC=CC(NCC3=NN=C(C4=CC=NC=C4)N3C)=C2. Product ID: ACM865608113. Alfa Chemistry ISO 9001:2015 Certified.
CMPD101
CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors. Synonyms: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide. Grade: 98%. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.46.
CMPD-39
CMPD-39 is a selective non-covalent inhibitor of the ubiquitin-specific protease USP30 (IC50=~20 nM), with high selectivity over other DUB family members (1-100 ?M). CMPD-39 inhibits the deubiquitinating activity of USP30, enhances the ubiquitination of mitochondrial proteins TOMM20 and SYNJ2BP; thus, CMPD-39 promotes phosphoubuitin accumulation, thereby accelerating mitochondrial autophagy (mitophagy) and peroxisomal autophagy (pexophagy). CMPD-39 significantly restores impaired mitochondrial function in dopaminergic neurons derived from Parkinson's disease patients[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2242582-40-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141659.
CMPDA
CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. Synonyms: CMPDA; 380607-77-2; N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide; A36XX25K37; N-[2-[4-[2-(propan-2-ylsulfonylamino)ethyl]phenyl]ethyl]propane-2-sulfonamide; N,N'-(Benzene-1,4-Diyldiethane-2,1-Diyl)dipropane-2-Sulfonamide; 2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis-; UNII-A36XX25K37; SCHEMBL6565144; BCP23929; AKOS024458123; CS-3632; HY-12508; MS-26117; E99011; Q27465085; N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonamide; RNN. Grade: >98%. CAS No. 380607-77-2. Molecular formula: C16H28N2O4S2. Mole weight: 376.53.
CMPDA (N,N'-1,4-Phenylenedi-2,1-ethanediyl bis-2-propanesulfonamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 380607-77-2. Pack Sizes: 10mg. Molecular Formula: C16H28N2O4S2, Biological Activity: Positive allosteric modulator of GluR2 receptors (EC50 values are 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. US Biological Life Sciences.
Worldwide
CMPF
CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 86879-39-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-129297.
CMPI [2-Chloro-1-methylpyridinium iodide]
CMPI [2-Chloro-1-methylpyridinium iodide]. Group: Biochemicals. Grades: Highly Purified. CAS No. 14338-32-0. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
CMP - lyophilized
CMP - lyophilized is an extensively employed biomolecule in the field of biomedical sciences due to its pivotal involvement in the intricate processes of DNA research and development and repair. Through serving as a fundamental constituent for nucleic acids, CMP assuming a critical role in facilitating cellular functions. Synonyms: Cytidine-5'-monophosphate, Disodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N3O8P (free acid). Mole weight: 323.20 (free acid).
CMP-N-acetylneuraminate monooxygenase
This enzyme contains both a Rieske-type [2Fe-2S] cluster and a second iron site. The ferricytochrome b5 produced is reduced by NADH and cytochrome-b5 reductase (EC 1.6.2.2). The enzyme can be activated by Fe2+ or Fe3+. Group: Enzymes. Synonyms: CMP-N-acetylneuraminic acid hydroxylase; CMP-Neu5Ac hydroxylase; cytidine monophosphoacetylneuraminate monooxygenase; N-acetylneuraminic monooxygenase; cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase. Enzyme Commission Number: EC 1.14.18.2. CAS No. 116036-67-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0964; CMP-N-acetylneuraminate monooxygenase; EC 1.14.18.2; 116036-67-0; CMP-N-acetylneuraminic acid hydroxylase; CMP-Neu5Ac hydroxylase; cytidine monophosphoacetylneuraminate monooxygenase; N-acetylneuraminic monooxygenase; cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase. Cat No: EXWM-0964.
CMP-N-acetylneuraminic acid 9-sp-biotin
CMP-N-acetylneuraminic acid 9-sp-biotin.
CMP-N-acetylneuraminic acid sodium salt
CMP-N-acetylneuraminic acid sodium salt, a fundamental compound employed in the field of biomedicine, exhibits immense utility in the management of diverse ailments associated with compromised sialic acid metabolism, including sialuria and sialic acid storage diseases. Synonyms: CMP-NANA; Cytidine 5-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid; CMP-Neu5Ac. CAS No. 3063-71-6. Molecular formula: C20H30N4NaO16P. Mole weight: 636.43.
CMP-N-acylneuraminate phosphodiesterase
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Enzyme Commission Number: EC 3.1.4.40. CAS No. 55326-41-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3724; CMP-N-acylneuraminate phosphodiesterase; EC 3.1.4.40; 55326-41-5; CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Cat No: EXWM-3724.
CMP-Neu5,9Ac2
CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Synonyms: β-Neuraminic acid, N-acetyl-, 9-acetate 2-(hydrogen 5'-cytidylate), ammonium salt (1:2). CAS No. 1045785-97-4. Molecular formula: C22H33N4O17P.2NH3. Mole weight: 690.55.
CMP-Neu5Ac sodium salt
CMP-Neu5Ac sodium salt, a vital compound in the biomedical sector, is intricately involved in numerous biological processes, aiding in the synthesis of sialylated compounds. Notably, its indispensable role as a substrate for sialyltransferases facilitates the treatment of ailment manifestations characterized by aberrant sialylation. Afflicting individuals are plagued by a range of conditions, including cancer, neurological disorders, and autoimmune diseases, wherein CMP-Neu5Ac sodium salt assumes significance. Synonyms: CMP-NANA; Cytidine 5'-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid. Grade: 85%. CAS No. 1007117-62-5. Molecular formula: C20H30N4O16P·Na. Mole weight: 636.43.
CMP-Neu5Az sodium
CMP-Neu5Az is a modified sialic acid nucleotide commonly used in glycosylation research, particularly for bioorthogonal labeling and metabolic engineering of sialic acids. Grade: ≥85%. Molecular formula: C20H28N7Na2O16P. Mole weight: 699.43.
CMP-N-glycolylneuraminic acid
CMP-N-glycolylneuraminic acid is a fundamental compound extensively used in the biomedical field, serving as an indispensable precursor in the research and development of diverse sialic acid derivatives, which wield significant influence over a plethora of intricate biological mechanisms. Synonyms: N-(2-hydroxyacetyl)-b-neuraminic acid 2-(hydrogen 5-cytidylate); CMP-NeuGc. CAS No. 98300-80-2. Molecular formula: C20H31N4O17P. Mole weight: 630.45.
CMP-N,N'-diacetyllegionaminic acid synthase
Isolated from the bacteria Legionella pneumophila and Campylobacter jejuni. Involved in biosynthesis of legionaminic acid, a sialic acid-like derivative that is incorporated into virulence-associated cell surface glycoconjugates which may include lipopolysaccharide (LPS), capsular polysaccharide, pili and flagella. Group: Enzymes. Synonyms: CMP-N,N'-diacetyllegionaminic acid synthetase; neuA (gene name); legF (gene name). Enzyme Commission Number: EC 2.7.7.82. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3295; CMP-N,N'-diacetyllegionaminic acid synthase; EC 2.7.7.82; CMP-N,N'-diacetyllegionaminic acid synthetase; neuA (gene name); legF (gene name). Cat No: EXWM-3295.
CMP-Pseudaminic acid is a compound of immense value, serving as a fundamental building block for the bioresearch and development of pseudaminic acid, a vital constituent of bacterial glycosylated proteins. By impeding enzymatic development, CMP-Pseudaminic acid reveals promising prospects for research of bacterial infections triggered by notorious pathogens like Campylobacter jejuni and Helicobacter pylori. Synonyms: CMP-Pse. Molecular formula: C22H34N5O15P. Mole weight: 639.5.
CMP-Sialic acid sodium salt
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates [1]. Uses: Scientific research. Group: Natural products. Alternative Names: CMP-Neu5Ac sodium salt. CAS No. 1007117-62-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112942A.
CMP-Sialic Acid Synthetase from Neisseria meningitidis group B, Recombinant
In enzymology, a N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) is an enzyme that catalyzes the chemical reaction:CTP + N-acylneuraminate<-> diphosphate + CMP-N-acylneuraminate. Thus, the two substrates of this enzyme are CTP and N-acylneuraminate, whereas its two products are diphosphate and CMP-N-acylneuraminate. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). This enzyme participates in aminosugars metabolism. Applications: The enzyme has been utilized to synthesize cmp-sialic acid and its derivatives. Group: Enzymes. Synonyms: EC 2.7.7.43; N-acylneuraminate cytidylyltransferase; CMP-sialate pyrophosp. Enzyme Commission Number: EC 2.7.7.43. CAS No. 9067-82-7. Acid Synthetase. Activity: > 10 units/mg protein. Storage: -20°C. Form: , Supplied as a lyophilized powder containing Tris-HCl and NaCl. Source: E. coli BL21. Species: Neisseria meningitidis group B. EC 2.7.7.43; N-acylneuraminate cytidylyltransferase; CMP-sialate pyrophosphorylase; CMP-sialate synthase; cytidine 5'-monophosphosialic acid synthetase; CMP-Neu5Ac synthetase; CMP-NeuAc synthetase; acylneuraminate cytidyltransferase; CMP-N-acetylneuraminate synthetase; CMP-N-acetylneuraminate synthase; CMP-N-acetylneuraminic acid synthase; CMP-
Cm sephadex,c-50
Cm sephadex,c-50. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CM Sephadex, Carboxymethyl Sephadex. Product Category: Heterocyclic Organic Compound. CAS No. 9047-8-9. Product ID: ACM904789. Alfa Chemistry ISO 9001:2015 Certified.
CMX 001
CMX 001 is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells.An alkoxyalkyl ester prodrug containing the synthetic, acyclic nucleoside monophosphate analog cidofovir linked, through its phosphonate group, to a lipid, 3-hexadecyloxy-1-propanol, with antiviral activity against double-stranded DNA viruses. Uses: Broad spectrum antiviral drug. Synonyms: CMX 001; CMX-001; CMX001; HDP-CDV; HDPCDV; Brincidofovir; [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-(3-hexadecoxypropoxy)phosphinic acid. Grade: ≥98%. CAS No. 444805-28-1. Molecular formula: C27H52N3O7P. Mole weight: 561.70.
c-Myc inhibitor 4
c-Myc inhibitor 4 is a potent and orally bioavailable c-MYC-reducing compound. Synonyms: 2-[6-[(2S,5S)-2,5-dimethylpyrrolidin-1-yl]pyridin-3-yl]-4-fluoro-7-methoxy-N-methyl-1-[[(2S)-morpholin-2-yl]methyl]benzimidazole-5-carboxamide. Molecular formula: C26H33FN6O3. Mole weight: 496.58.
c-Myc Inhibitor - CAS 403811-55-2
The c-Myc Inhibitor, also referenced under CAS 403811-55-2, controls the biological activity of c-Myc. Group: Fluorescence/luminescence spectroscopy.
c-Myc Inhibitor II - CAS 413611-93-5
The c-Myc Inhibitor II, also referenced under CAS 413611-93-5, controls the biological activity of c-Myc. Group: Fluorescence/luminescence spectroscopy.
c-Myc Inhibitor III, Mycro2
The c-Myc Inhibitor III, Mycro2 controls the biological activity of c-Myc. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable pyrazolopyrimidine-carboxamide that selectively inhibits c-Myc-Max dimer DNA binding activity (IC50=23uM) by preventing c-Myc-Max heterodimer formation, while affecting Max, Jun, C/EBPa homodimers, or Jun-Fos heterodimer DNA binding only at much higher concentrations (IC50=>54uM). Shown to selectively inhibit c-Myc-Max-dependent transcription (by 77% against E-Box promoter-driven reporter transcription at 10uM), cancer proliferation, and anchorage-independent colony formation (Effective conc. 10-20uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
c-Myc Peptide
c-Myc Peptide Trifluoroacetate is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription. Synonyms: H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH; L-alpha-glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucine; L-Leucine, L-α-glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-; L-Leucine, N-[N-[N-[N-[N-[N-[N-[N2-(N2-L-α-glutamyl-L-glutaminyl)-L-lysyl]-L-leucyl]-L-isoleucyl]-L-seryl]-L-α-glutamyl]-L-α-glutamyl]-L-α-aspartyl]-; L-α-Glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-L-leucine; c-Myc epitope tag; c-Myc-tag; cMYC tag (synthetic); Myc peptide; Myc-tag; Neuroblastoma suppressor of tumorigenicity 1 (human clone WO2014/074532-SEQID-317); Transcription factor c-myc (fragment); Transcription factor c-myc (synthetic C-terminal epitope). Grade: ≥95%. CAS No. 145646-22-6. Molecular formula: C51H86N12O21. Mole weight: 1203.30.
c-Myc Peptide (TFA) is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription. Uses: Scientific research. Group: Peptides. CAS No. 2918768-02-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0312.
c-Myc Peptide Trifluoroacetate
It is a synthetic peptide corresponding to the C-terminal amino acid (410-419) of human c-Myc protein and is involved in the regulation of growth-related gene transcription. Synonyms: C-MYC PEPTIDE EPITOPE TFA; Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu TFA; c-Myc peptide epitope TFA; L-alpha-Glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucine trifluoroacetate (1:1). Grade: ≥95%. CAS No. 2918768-02-0. Molecular formula: C51H86N12O21.C2HF3O2. Mole weight: 1317.32.
C-myc, proto oncogene human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Cn-AMP1
Cn-AMP1 is an antimicrobial peptide produced by Cocos nucifera (Coconut palm, green coconut water). It has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Antimicrobial peptide 1; Ser-Val-Ala-Gly-Arg-Ala-Gln-Gly-Met; Cocos nucifera antimicrobial peptide 1. Grade: >96%. CAS No. 1158169-22-2. Molecular formula: C34H61N13O12S. Mole weight: 876.01.