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Clarithromycin-13C-d3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C3713CH66D3NO13. Mole Weight: 751.97. Catalog: APB07078.
Clarithromycin 2'-O-Acetate
Clarithromycin 2'-O-Acetate is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, which is a derivative of O-Methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: 2'-O-Acetylclarithromycin; 2'-O-Acetyl-6-O-methylerythromycin A; Oxacyclotetradecane Erythromycin Derivative; 6-O-Methyl-erythromycin 2'-Acetate; (2S, 3R, 4S, 6R)-4-(Dimethylamino)-2-(((3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-14-ethyl-12, 13-dihydroxy-4-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3, 5, 7, 9, 11, 13-hexamethyl-2, 10-dioxooxacyclotetradecan-6-yl)oxy)-6-methyltetrahydro-2H-pyran-3-yl Acetate. CAS No. 103461-66-1. Molecular formula: C40H71NO14. Mole weight: 789.99.
Clarithromycin 2'-O-Acetate N-Methyl Iodide
Clarithromycin 2'-O-Acetate N-Methyl Iodide is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, which is a derivative of O-Methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Molecular formula: C41H74INO14. Mole weight: 931.93.
A semi-synthetic macrolide antibiotic. A derivative of erythromycin. Group: Biochemicals. Alternative Names: 6-O-Methylerythromycin, A-56268, TE-031, Biaxin. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Clarithromycin (9E)-O-Methyloxime
Clarithromycin (9E)-O-Methyloxime (Clarithromycin EP Impurity G) is an impurity of Clarithromycin, a macrolide antibiotic. Clarithromycin impurity G. Synonyms: 6-O-Methylerythromycin (9E)-9-(O-Methyloxime); Clarithromycin Impurity G; Clarithromycin EP Impurity G. Grades: 98%. CAS No. 127182-44-9. Molecular formula: C39H72N2O13. Mole weight: 776.99.
Clarithromycin 9-Oxime
Clarithromycin 9-Oxime is an impurity of Clarithromycin , a macrolide antibiotic. Group: Biochemicals. Alternative Names: 6-O-Methylerythromycin 9-Oxime; 6-O-Methylerythromycin A 9-Oxime. Grades: Highly Purified. CAS No. 103450-87-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Clarithromycin EP Impurity A
Clarithromycin EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3-(hydroxymethyl)-7-methoxy-5,7,9,11,13-pentamethyloxacyclotetradecane-2,10-dione. CAS No. 124412-58-4. Molecular Formula: C38H69NO14. Mole Weight: 763.95. Catalog: APB124412584.
Clarithromycin EP Impurity D
Clarithromycin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101666-68-6. Molecular Formula: C37H67NO13. Mole Weight: 733.94. Catalog: APB101666686.
Clarithromycin EP Impurity E
Clarithromycin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,12-dimethoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione. CAS No. 81103-14-2. Molecular Formula: C39H71NO13. Mole Weight: 761.98. Catalog: APB81103142.
Clarithromycin EP Impurity P
4'',6-Di-O-methylerythromycin is a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: 4'',6-Di-O-methylerythromycin; Oxacyclotetradecane, Erythromycin deriv.; 4'-O-Methylclarithromycin. Grades: > 95%. CAS No. 123967-58-8. Molecular formula: C39H71NO13. Mole weight: 761.98.
Clarithromycin EP Impurity P
Clarithromycin EP Impurity P. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(((2R,4R,5S,6S)-4,5-dimethoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione. CAS No. 123967-58-8. Molecular Formula: C39H71NO13. Mole Weight: 761.98. Catalog: APB123967588.
Clarithromycin Hydrazone
Clarithromycin Hydrazone is an intermediate in the synthesis of 12-O-Methyl Clarithromycin which is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin. 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. Synonyms: 6-O-Methylerythromycin Hydrazone; 6-O-Methyl-erythromycin 9-Hydrazone. Molecular formula: C38H71N3O12. Mole weight: 761.98.
Clarithromycin Impurity 14
Clarithromycin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 138109-92-9. Molecular Formula: C38H69NO13. Mole Weight: 747.96. Catalog: APB138109929.
Clarithromycin impurity 17
Clarithromycin impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 110671-78-8. Molecular Formula: C38H69NO14. Mole Weight: 763.96. Catalog: APB110671788.
Clarithromycin Impurity B
Clarithromycin Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13,14-heptamethylo. CAS No. 299409-85-1. Molecular Formula: C37H67NO13. Mole Weight: 733.93. Catalog: APB299409851.
Clarithromycin Impurity C
Clarithromycin Impurity C is an impurity of Clarithromycin, an antibiotic used to treat a variety of bacterial infections. Synonyms: Clarithromycin oxime. Grades: > 95%. CAS No. 127253-06-9. Molecular formula: C38H70N2O13. Mole weight: 762.97.
Clarithromycin Impurity E
A Di-O-alkyl Erythromycin is an impurity of Clarithromycin. Clarithromycin impurity E per British Pharmacopoeia. Synonyms: 6,11-Di-O-methylerythromycin; 11-O-Methylclarithromycin; USP Clarithromycin Related Compound A. Grades: > 95%. CAS No. 81103-14-2. Molecular formula: C39H71NO13. Mole weight: 761.98.
Clarithromycin Impurity F
Clarithromycin Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,13-dimethoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione. CAS No. 128940-83-0. Molecular Formula: C39H71NO13. Mole Weight: 761.98. Catalog: APB128940830.
Clarithromycin impurity GA
Clarithromycin impurity GA. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H94N2O15Si2. Mole Weight: 994.62. Catalog: APB07064.
Clarithromycin impurity GD
Clarithromycin impurity GD. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C51H102N2O14Si3. Mole Weight: 1050.66. Catalog: APB07066.
Clarithromycin impurity GK
Clarithromycin impurity GK. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H57NO8Si. Mole Weight: 611.39. Catalog: APB07069.
Clarithromycin Impurity G (Mixture of Z and E Isomers)
Clarithromycin Impurity G (Mixture of Z and E Isomers) is a an impurity of Clarithromycin, an antibiotic widely employed in treating various bacterial infections, including respiratory tract infections, skin and soft tissue infections and Helicobacter pylori infections associated with peptic ulcers. Grades: > 95%. CAS No. 107216-09-1. Molecular formula: C39H72N2O13. Mole weight: 777.01.
Clarithromycin impurity GN
Clarithromycin impurity GN. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H92N2O13Si2. Mole Weight: 960.61. Catalog: APB07070.
Clarithromycin impurity GWB
Clarithromycin impurity GWB. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C44H86N2O13Si2. Mole Weight: 906.57. Catalog: APB07065.
Clarithromycin impurity GWQ
Clarithromycin impurity GWQ. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C47H94N2O13Si3. Mole Weight: 978.61. Catalog: APB07067.
Clarithromycin Impurity J
Clarithromycin Impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R, 4S, 5S, 6R, 7R, 9R, 11S, 12R, 13S, 14R, E)-6-(((2S, 3R, 4S, 6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7, 12, 13-trihydroxy-4-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3, 5, 7, 9, 11, 13-hexamethyloxacyclotetradecan-2-one. CAS No. 13127-18-9. Molecular Formula: C37H68N2O13. Mole Weight: 748.94. Catalog: APB13127189.
Clarithromycin impurity JA
Clarithromycin impurity JA. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H96N2O15Si2. Mole Weight: 1008.63. Catalog: APB07068.
Clarithromycin impurity JB
Clarithromycin impurity JB. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H94N2O14Si2. Mole Weight: 979.45. Catalog: APB07071.
Clarithromycin impurity JD
Clarithromycin impurity JD. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C48H94N2O14Si2. Mole Weight: 979.45. Catalog: APB07072.
Clarithromycin impurity JE
Clarithromycin impurity JE. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H98N2O14Si2. Mole Weight: 1006.66. Catalog: APB07073.
Clarithromycin impurity JF
Clarithromycin impurity JF. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H98N2O14Si2. Mole Weight: 1006.66. Catalog: APB07074.
Clarithromycin impurity JG
Clarithromycin impurity JG. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C45H88N2O13Si2. Mole Weight: 920.58. Catalog: APB07075.
Clarithromycin impurity JK
Clarithromycin impurity JK. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C33H59NO8Si. Mole Weight: 625.4. Catalog: APB07076.
Clarithromycin impurity JN
Clarithromycin impurity JN. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C49H94N2O13Si2. Mole Weight: 974.63. Catalog: APB07077.
Clarithromycin Impurity N. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S,5S,6R,7R,9R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacycl. CAS No. 144604-03-5. Molecular Formula: C38H67NO12. Mole Weight: 729.94. Catalog: APB144604035.
Clarithromycin Impurity N
(10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin is the Erythromycin derivative. Synonyms: (10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin; Oxacyclotetradecane Erythromycin Derivative. Grades: > 95%. CAS No. 144604-03-5. Molecular formula: C38H67NO12. Mole weight: 729.94.
Clarithromycin Impurity O
Clarithromycin (9Z)-O-Methyloxime is an impurity of Clarithromycin. Synonyms: Clarithromycin (9Z)-O-Methyloxime; 6-O-Methylerythromycin (9Z)-9-O-Methyloxime; Oxacyclotetradecane Erythromycin deriv. Grades: > 95%. CAS No. 127252-80-6. Molecular formula: C39H72N2O13. Mole weight: 776.99.
A labeled semi-synthetic macrolide antibiotic. A derivative of erythromycin. Group: Biochemicals. Alternative Names: 6-O-Methylerythromycin-N-methyl-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Clarithromycin N-Oxide
Clarithromycin N-oxide is an urinary metabolite of Clarithromycin, a macrolide antibiotic. Synonyms: 6-O-Methylerythromycin N-Oxide; USP Clarithromycin Impurity Q. Grades: > 95%. CAS No. 118074-07-0. Molecular formula: C38H69NO14. Mole weight: 763.95.
Clarithromycin N-OxiMe
Clarithromycin N-OxiMe. Uses: For analytical and research use. Group: Impurity standards. CAS No. 103450-87-9. Molecular Formula: C38H70N2O13. Mole Weight: 762.98. Catalog: APB103450879.
Clarithromycin related compound C
An impurity found in the macrolide antibiotic, Clarithromycin. Synonyms: 6-O-Methylerythromycin 9-Oxime; Clarithromycin Impurity C. Grades: >95% by HPLC. CAS No. 103450-87-9. Molecular formula: C38H70N2O13. Mole weight: 762.97.
Clarithromycin related compound H
N-Demethyl-N-formylclarithromycin is an impurity of the semi-synthetic macrolide antibiotic Clarithromycin. Synonyms: N-Demethyl-N-formyl Clarithromycin; N-Demethyl-N-formyl-6-O-methylerythromycin; 3"-N-Demethyl-3"-N-formylclarithromycin; USP Clarithromycin Impurity H; Clarithromycin impurity H. Grades: >95%. CAS No. 127140-69-6. Molecular formula: C38H67NO14. Mole weight: 761.94.
Clarithromycin related compound I
An impurity found in the macrolide antibiotic, Clarithromycin. Synonyms: De(cladinosyl) Clarithromycin; 3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-6-O-methylerythromycin; 5-O-Desosaminyl-6-O-methylerythronolide A; 3-O-Decladinosyl-6-O-methylerythronolide A; Clarithromycin EP Impurity I. Grades: ≥90.0%. CAS No. 118058-74-5. Molecular formula: C30H55NO10. Mole weight: 589.77.
Clarithromycin related compound K
3-O-De(cladinosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy Clarithromycin is an impurity of Clarithromycin. Synonyms: 3-O-De(cladinosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy Clarithromycin; 3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-8,9,10,11-tetradehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-6-O-methylerythromycin; Clarithromycin EP Impurity K. Grades: >95%. CAS No. 127157-35-1. Molecular formula: C30H51NO8. Mole weight: 553.73.
Clarithromycin related compound M
N-Desmethyl-6-O-methylerythromycin (9E)-Oxime is a derivative of Clarithromycin. Synonyms: N-Desmethyl-6-O-methylerythromycin (9E)-Oxime; 3''-N-Demethyl-6-O-methylerythromycin A (E)-9-oxime. Grades: >95%. CAS No. 127182-43-8. Molecular formula: C37H68N2O13. Mole weight: 748.94.
Clarithromycin (Standard)
Clarithromycin (Standard) is the analytical standard of Clarithromycin. This product is intended for research and analytical applications. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17508R.
Clarithromycin Trimethylsilyl O-Methyl Trityl Hydrazone is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: (3R, 4S, 5S, 6R, 7R, 9R, 11S, 12R, 13S, 14R, E)-4-(((2R, 4R, 5S, 6S)-4, 5-Dimethoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S, 3R, 4S, 6R)-4-(dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12, 13-dihydroxy-7-methoxy-3, 5, 7, 9, 11, 13-hexamethyl-10-(2-tritylhydrazono)oxacyclotetradecan-2-one. Molecular formula: C61H95N3O12Si. Mole weight: 1090.51.
Clarithromycin Trimethylsilyl Trityl Hydrazone
Clarithromycin Trimethylsilyl Trityl Hydrazone is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: (3R, 4S, 5S, 6R, 7R, 9R, 11S, 12R, 13S, 14R, E)-6-(((2S, 3R, 4S, 6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12, 13-dihydroxy-4-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3, 5, 7, 9, 11, 13-hexamethyl-10-(2-tritylhydrazono)oxacyclotetradecan-2-one. Molecular formula: C60H93N3O12Si. Mole weight: 1076.48.
Clarithromycin Trityl Hydrazone
Clarithromycin Trityl Hydrazone is an intermediate in synthesizing 4'',6-Di-O-methylerythromycin, a derivative of O-methylerythromycin and may be used in the treatment of lung diseases requiring antibiotics. Synonyms: (9E)?-6-O-Methyl-erythromycin 9-[2-(Triphenylmethyl)?hydrazone]; (3R, 4S, 5S, 6R, 7R, 9R, 11S, 12R, 13S, 14R, E)-6-(((2S, 3R, 4S, 6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12, 13-dihydroxy-4-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3, 5, 7, 9, 11, 13-hexamethyl-10-(2-tritylhydrazono)oxacyclotetradecan-2-one. CAS No. 1030374-65-2. Molecular formula: C57H85N3O12. Mole weight: 1004.3.
Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cortexolone 17 alpha-propionate; Cortexolone 17α-propionate; CB-03-01. CAS No. 19608-29-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13331.
Class A CpG oligonucleotide (Mouse specific)
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in specific sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA than in mammalian DNA. CpG ODNs are recognized by Toll-like receptor 9 (TLR9), which leads to strong immunostimulatory effects.ODN 1585 is a class A CpG ODN specific for mouse TLR9. Class A CpG ODNs are characterized by a central, phosphodiester, CpG-containing palindromic motif and a 3'phosphorothioate poly-G string.They induce high IFN-α production from plasmacytoid dendritic cells (pDCs) but are weak stimulators of TLR9-dependent NF-κB signaling. Group: Others. Synonyms: CpG oligonucleotides; ODNs; ODN 1585; CpG ODNs; CpG. Storage: Upon receipt, store at -20 °C. Form: Lyophilized powder. CpG oligonucleotides; ODNs; ODN 1585; CpG ODNs; CpG. Cat No: LIGC-010.
classical-complement-pathway C3/C5 convertase
A complex of complement fragments C4b, C2a and C2b. C2a contains the active site, C2b the site for C4b binding. C2a and C2b are formed by cleavage of proenzyme C2 by complement subcomponent C1s. Cleavage of C5 requires complement fragment C3b which binds C5 and renders it susceptible to cleavage by the C4b,2a complex. Includes former EC 3.4.21.44. Complement component C2a is in peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C3 convertase; C42; C4b,2a; C5 convertase; C423; C4b,2a,3b; C42; C5 convertase; C423; C4b,2a,3b; complement C.hivin.4.hivin2; complement C3 convertase. Enzyme Commission Number: EC 3.4.21.43. CAS No. 56626-15-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4137; classical-complement-pathway C3/C5 convertase; EC 3.4.21.43; 56626-15-4; C3 convertase; C42; C4b,2a; C5 convertase; C423; C4b,2a,3b; C42; C5 convertase; C423; C4b,2a,3b; complement C.hivin.4.hivin2; complement C3 convertase. Cat No: EXWM-4137.
Class II sec-dependent bacteriocin
Class II sec-dependent bacteriocin is from Enterococcus hirae. It has antimicrobial activity.
Cell-permeable. A highly specific, potent and irreversible proteasome inhibitor. Lactacystin acts as a precursor for clasto-lactacystin beta-lactone and the latter compound is at least 10 times more active than the parent Lactacystin. Group: Biochemicals. Grades: Highly Purified. CAS No. 154226-60-5. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
clasto-Lactacystin β-lactone
Clasto-Lactacystin β-lactone, a natural active metabolite of lactacystin, which is a metabolite of Streptomyces , acts as an irreversible 20S proteasome inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: Omuralide; β-Clastolactacystin. CAS No. 154226-60-5. Pack Sizes: 50 μg (2.34 mM * 100 μL in Methyl acetate). Product ID: HY-108549.
Clasto-Lactacystin β-lactone
Clasto-Lactacystin β-lactone is a microbial metabolite isolated from Streptomyces that is now widely used as a selective inhibitor of the 20S proteasome. Clasto-lactacystin β-lactone was later identified as the active metabolite of lactacystin, resulting from the elimination of cysteine and the formation of a reactive β-lactone. It is 20-fold more potent than Lactacystin. Synonyms: β-Clastolactacystin; Omuralide. Grades: ≥95%. CAS No. 154226-60-5. Molecular formula: C10H15NO4. Mole weight: 213.23.
Clasto-Lactacystin beta-lactone (Omuralide)
In vitro lactacystin does not react with the proteasome. It rather undergoes a spontaneous conversion (lactonization) to the active metabolite clasto-lactacystin beta-lactone. Potent and selective irreversible and cell permeable proteasome inhibitor. Inhibits the chymotrypsin-like, trypsin-like and caspase-like peptidase activity of the proteasome. The active metabolite of lactacystin with higher potency since it does not require hydrolysis in order to become cell permeable. Calpain and cathepsin inhibitor. Apoptosis inducer. Anticancer compound. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Induces neuritogenesis. Autophagy inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 154226-60-5. Pack Sizes: 100ug. Molecular Formula: C10H15NO4, Molecular Weight: 213.2. US Biological Life Sciences.
A cell permeable, irreversible proteasome inhibitor. It is 20-fold more p. Group: Biochemicals. Alternative Names: Clasto-lactacystin b-Lactone, Omuralide. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Clasto-lactacystin(omuralide)
Clasto-lactacystin (omuralide). Group: Biochemicals. Alternative Names: (1R, 4R, 5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3. 2. 0]heptane-3, 7-dione; Clasto-lactacystin b-lactone; Omuralide. Grades: Highly Purified. CAS No. 154226-60-5. Pack Sizes: 1mg. Molecular Formula: C10H15NO4. US Biological Life Sciences.
It is produced by the strain of Strrptomyces clavuligerus. Clavam-2-carboxylate has the activity against part of fungi. Synonyms: SCHEMBL8589184. CAS No. 212268-81-0. Molecular formula: C6H7NO4. Mole weight: 157.12.
clavaminate synthase
Contains nonheme iron. Catalyses three separate oxidative reactions in the pathway for the biosythesis of the β-lactamase inhibitor clavulanate in Streptomyces clavuligerus. The first step (hydroxylation) is separated from the latter two (oxidative cyclization and desaturation) by the action of EC 3.5.3.22, proclavaminate amidinohydrolase. The three reactions are all catalysed at the same nonheme iron site. Group: Enzymes. Synonyms: clavaminate synthase 2; clavaminic acid synthase. Enzyme Commission Number: EC 1.14.11.21. CAS No. 122799-56-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0638; clavaminate synthase; EC 1.14.11.21; 122799-56-8; clavaminate synthase 2; clavaminic acid synthase. Cat No: EXWM-0638.
Clavamycin A
Clavamycin A is produced by the strain of Streptomyces hygroscopicus NRRL 15846. It has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase. Synonyms: Serine, 3-(7-oxo-4-oxa-1-azabicyclo(3.2.0)hept-3-yl)-N-(3-(7-oxo-4-oxa-1-azabicyclo(3.2.0)hept-3-yl)seryl)-. CAS No. 103059-93-4. Molecular formula: C16H22N4O9. Mole weight: 414.37.
Clavamycin B
Clavamycin B is produced by the strain of Streptomyces hygroscopicus NRRL 15846. It has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase. Synonyms: CHEBI:81031. Molecular formula: C13H22N4O8. Mole weight: 362.34.
Clavamycin C
Clavamycin C is produced by the strain of Streptomyces hygroscopicus NRRL 15846. It has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase. Synonyms: CHEBI:81032. Molecular formula: C13H22N4O8. Mole weight: 362.34.
Clavanin-A
Clavanin A was found in invertebrate Styela clava. It has antibacterial and antifungal activity. Clavanin A was in vitro evaluated against Staphylococcus aureus and Escherichia coli as well as toward L929 mouse fibroblasts and skin primary cells (SPCs). Grades: >96% by HPLC. Molecular formula: C131H184N34O27. Mole weight: 2667.07.
Clavanin-B
Clavanin B is an alpha-helical antimicrobial peptide isolated from Styela clava. Molecular formula: C131H184N36O27. Mole weight: 2695.08.