A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CKI 7 is a CK1 inhibitor, and also inhibits SGK, S6K1 and MSK1. In combination with SB 431542, CKI 7 was shown to induce retinal cell differentiation from human ESCs and iPSCs. Synonyms: CKI-7 dihydrochloride; N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride. Grades: >98%. CAS No. 1177141-67-1. Molecular formula: C11H14Cl3N3O2S. Mole weight: 358.67.
CKI-7 free base
CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC 50 of 6 μM and a K i of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK , ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120615-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133028.
CL075
CL075 is a thiazoloquinolone derivative that stimulates TLR8 in human peripheral blood mononuclear cells. It activates NF-κB and triggers preferentially the production of TNF-α and IL-12. CL075 seems also to induce the secretion of IFN-α through TLR7 but to a lesser extend. It induces the activation of NF-κB at 0.4 uM (0.1 ug/ml) in TLR8-transfected HEK293 cells, and ~ 10 times more CL075 is required to activate NF-κB in TLR7-transfected HEK293 cells. Group: Others. Mole weight: 243.33. Stability: Lyophilized product is stable 1 year at -20°C when properly stored. Resuspended CL075 should be aliquoted and stored at -20°C. Resuspended product is stable 6 months at -20°C. Avoid repeated freeze-thaw cycles. Appearance: Yellow lyophilized powder. Storage: Store at -20°C. CL075. Cat No: LIGC-007.
CL075
CL075 is a thiazoloquinolone derivative that stimulates TLR8 in human peripheral blood mononuclear cells. Uses: Toll-like receptor agonists. Synonyms: CL 075; CL-075; Thiazolo[4,5-c]quinolin-4-amine, 2-propyl-; 2-Propylthiazolo[4,5-c]quinolin-4-amine; 3M 002; 3M-002; 3M002. Grades: ≥95%. CAS No. 256922-53-9. Molecular formula: C13H13N3S. Mole weight: 243.33.
CL097
CL097 is a human TLR7/8 and mouse TLR7 agonist. Synonyms: CL 097; CL-097; 3H-Imidazo[4,5-c]quinolin-4-amine, 2-(ethoxymethyl)-; 2-(Ethoxymethyl)-1H-imidazo[4,5-C]quinolin-4-amine. Grades: ≥95%. CAS No. 1026249-18-2. Molecular formula: C13H14N40. Mole weight: 242.28.
CL 218872
CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABA A receptor with a K i of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66548-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103505.
CL 218872
CL 218872 has been found to be a benzodiazepine agonist and has been found to exhibit anxiolytic and anticonvulsant activities. Synonyms: CL 218872; CL218872; CL-218872; 3-Methyl-6-[-3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine. Grades: ≥99% by HPLC. CAS No. 66548-69-4. Molecular formula: C13H9F3N4. Mole weight: 278.24.
CL 218872
CL 218872. Group: Biochemicals. Grades: Purified. CAS No. 66548-69-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CL264
CL264 is a small-molecule agonist of TLR7. Synonyms: Glycine, N-[4-[[6-amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]-; N-[4-[[6-Amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]glycine; CL 246; CL 264; CL-264; (4-((6-amino-2-(butylamino)-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl)benzoyl)glycine. Grades: ≥95%. CAS No. 1510712-69-2. Molecular formula: C47H73N13O7S. Mole weight: 413.43.
CL2 Linker
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours). CAS No. 2270986-66-6. Molecular formula: C68H103N11O22. Mole weight: 1426.61.
CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC 50 of 3 nM, but is an extremely poor to β1/2- receptors [1].CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate [2]. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138908-40-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116771A.
CL-316243
CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM) with > 10000-fold selective over β1 and β2 receptors. CL 316243 possesses anti-obesity and anti-diabetic effects due to increasing brown adipose tissue thermogenesis and metabolic rate, and consequently may be useful for treating obesity as well as non-insulin-dependent diabetes mellitus in obese persons, without causing excessive side effects. Synonyms: CL-316243; CL 316243; CL316243; 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate; 138908-40-4 (CL-316243 sodium). Grades: >98%. CAS No. 183720-02-7. Molecular formula: C20H20ClNNa2O7. Mole weight: 419.794.
CL 316243 disodium salt
The sodium salt form of CL 316243, which has been found to be a β3-adrenoceptor agonist and could probably decrease blood insulin as well as glucose levels. Synonyms: CL 316243 disodium salt; CL316243 disodium salt; CL-316243 disodium salt; 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid disodium salt. Grades: ≥98% by HPLC. CAS No. 151126-84-0. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.80.
CL 316243 free acid
CL316243 free acid is a highly potent selective β3-adrenoceptor agonist with a EC 50 of 3 nM, but is an extremely poor to β1/2- receptors. CL316243 free acid is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 free acid has the potential for the treatment obesity, diabetes and urge urinary incontinence [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183720-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-116771.
A very potent agonist highly selective for beta-3 adrenoceptors (EC50 = 3nM). Widely used to assess the functional roles of beta-3 adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation. Group: Biochemicals. Grades: Highly Purified. CAS No. 138908-40-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CL-316243 sodium
CL-316243 is a highly selective β3-adrenoceptor agonist with EC50 value of 3 nM; > 10000-fold selective over β1 and β2 receptors. CL-316243 can restore the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice and enhance insulin-stimulated glucose disposal in nonobese rats. Preclical trials for the treatment of Obesity, Overactive bladder and Type 2 diabetes mellitus were discontinued. Uses: Obesity; overactive bladder; type 2 diabetes mellitus. Synonyms: CL-316243 sodium; CL 316243 sodium; CL316243 sodium; disodium;5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate;BTA 243; HP 186; BTA243; HP186; BTA-243; HP-186. Grades: 98%. CAS No. 138908-40-4. Molecular formula: C20H18ClNNa2O7. Mole weight: 465.79.
CL-387785
CL-387785, also known as EKI-785, is an irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC50 = 250-490 pM). CL-387785 covalently bound to EGF-R. It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM), blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31-125 nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2, and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice (when given orally at 80 mg/kg/day for 10 days, daily). CL-387,785 is useful for studying the interaction of small molecules with EGF-R and may have clinical utility. Uses: Protein kinase inhibitors. Synonyms: CL-387785; CL 387785; CL-387,785; CL387785; EKI-785; EKI 785; EKI785. Grades: 0.98. CAS No. 194423-06-8. Molecular formula: C18H13BrN4O. Mole weight: 381.233.
CL 43356
CL 43356 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CL 43356; CL 43356; CL 43356; CL-43,356; O,O-dimethyl 1,3-dithiolan-2-ylidenephosphoramidothioate;N-dimethoxyphosphinothioyl-1,3-dithiolan-2-imine. Grades: ≥98%. CAS No. 3572-55-2. Molecular formula: C5H10NO2PS3. Mole weight: 242.96.
Cl-4AS-1
Cl-4AS-1 is a mouse mammary tumor virus (MMTV) promoter and represses MMP1 promoter activity. It also inhibits 5α-Reductase type I and II with IC50 values of 6 and 10 nM respectively, as well as is a potent steroidal androgen receptor agonist with IC50 value of 12 nM. It mimics the action of 5α-dihydrotestosterone (DHT). Synonyms: (4aα, 4bβ, 6aα, 7α, 9aβ, 9bα, 11aβ)-N-(2-Chlorophenyl)-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecahydro-1, 4, 6a-trimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide. Grades: ≥99% by HPLC. CAS No. 188589-66-4. Molecular formula: C26H33ClN2O2. Mole weight: 441.01.
Cl-4AS-1
Cl-4AS-1. Group: Biochemicals. Grades: Purified. CAS No. 188589-66-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CL656
CL656 is an agonist of stimulator of interferon genes (STING) for treating cancer. Synonyms: c-[2'FdAMP(S)-2'FdIMP(S)]; cAIM(PS)2 Difluor (Rp/Sp); Adenosine, 2'-deoxy-2'-fluoro-5'-O-(hydroxymercaptophosphinyl)-P-thioinosinylyl-(3'?5')-2'-deoxy-2'-fluoro-, cyclic nucleotide; CL 656; CL-656; (Rp/Sp) c-[2'FdAM(PS)-2'FdIM(PS]); 9-((2R, 3R, 3aR, 7aR, 9R, 10R, 10aR, 14aR)-9-(6-amino-9H-purin-9-yl)-3, 10-difluoro-12-hydroxy-5-mercapto-5-oxido-12-sulfidooctahydro-2H, 7H-difuro[3, 2-d:3', 2'-j][1, 3, 7, 9]tetraoxa[2, 8]diphosphacyclododecin-2-yl)-1, 9-dihydro-6H-purin-6-one. Grades: >98%. CAS No. 1951464-79-1. Molecular formula: C20H21F2N9O9P2S2. Mole weight: 695.51.
CL 82,198
CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13). It doesn't have effect against MMP-1, MMP-9 or TNF-α converting enzyme. CL 82,198 is also used to evaluate the role of MMP-13 in diverse processes, including cancer cell migration, acute lung injury, and joint degeneration associated with osteoarthritis. Synonyms: CL-82198; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide. Grades: ≥95%. CAS No. 307002-71-7. Molecular formula: C17H22N2O3. Mole weight: 302.4.
CL 82198 hydrochloride
The hydrochloride salt form of CL 82198, an inhibitor of MMP-13, has been found to restrain in vitro invasion by the human pituitary adenoma cell line HP75. Synonyms: CL 82198 hydrochloride; CL82198 hydrochloride; CL-82198 hydrochloride; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1188890-36-9. Molecular formula: C17H23N2O3.HCl. Mole weight: 338.83.
CL 82198 hydrochloride
CL 82198 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1188890-36-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ClAc-Gly-OH
ClAc-Gly-OH. Group: Biochemicals. Alternative Names: Chloracetyl glycine; (2-Chloro-acetylamino)-acetic acid. Grades: Highly Purified. CAS No. 6319-96-6. Pack Sizes: 10g, 25g. US Biological Life Sciences.
ClAc-Gly-OH 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 6319-96-6. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Worldwide
Cladinose
Cladinose, an imperative chemical modification present in the macrolide category of antibacterial medications, demonstrates its excellence in combating Gram-positive bacteria, even the drug-resistant variants. With its pivotal role, Cladinose actively treats bacterial infections involving pneumonia, respiratory tract infections, skin and soft tissue infections, as well as selective sexually transmitted diseases. Notably, the inclusion of Cladinose remarkably enhances the efficiency and potency of these antibiotics, thereby advancing their therapeutic outcomes. Synonyms: L-Cladinose; 2,6-Dideoxy-3-C-methyl-3-O-methyl-ribo-hexose; Azithromycin Impurity 4; (4R,5S,6S)-4-Methoxy-4,6-dimethyltetrahydro-2H-pyran-2,5-diol; 3-C,3-O-Dimethyl-2,6-dideoxy-D-ribo-hexose. Grades: ≥95%. CAS No. 470-12-2. Molecular formula: C8H16O4. Mole weight: 176.21.
Cladospirone bisepoxide
It is produced by the strain of Cladosporium sp. F-24707. Cladospirone bisepoxide has the ability to inhibit yeast, filamentous fungi, and bacterial, and can inhibit germination of Lepidium sativum at low concentrations. Synonyms: Cladospirone bisepoxide. CAS No. 155866-40-3. Molecular formula: C20H14O7. Mole weight: 366.32.
Antibiotic. Antibacterial and antifungal. Antitumor compound. Germination inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 152607-03-9, 155866-40-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cladospolide A
It is produced by the strain of Cladosporium sp. FT-0012. Cladospolide A has little antibacterial activity. Synonyms: (-)-Cladospolide A; Oxacyclododec-3-en-2-one, 5,6-dihydroxy-12-methyl-, (3E,5R,6S,12R)-. CAS No. 77663-54-8. Molecular formula: C12H20O4. Mole weight: 228.28.
Cladospolide B
It is produced by the strain of Cladosporium sp. FT-0012. Cladospolide B has little antibacterial activity. Synonyms: 4,5-di-epi-Cladospolide C. CAS No. 96443-55-9. Molecular formula: C12H20O4. Mole weight: 228.28.
Cladospolide D
It is produced by the strain of Cladosporium sp. FT-0012. Cladospolide D has the activity against part of fungi. CAS No. 371229-61-7. Molecular formula: C12H18O4. Mole weight: 226.27.
Cladosporide A
It is produced by the strain of Cladosporium sp. IFM 49189. Cladosporide A inhibits Aspergillus fumigatus with IC50 of 0.5-4.0 μg/mL, but it has no effect on other filamentous fungi. CAS No. 310897-84-8. Molecular formula: C25H40O3. Mole weight: 388.58.
Cladosporide B
It is produced by the strain of Cladosporium sp. IFM 49189. Cladosporide B has slightly stronger anti-aspergillus fumigatus activity than A. CAS No. 376368-81-9. Molecular formula: C25H38O3. Mole weight: 386.57.
Cladosporin
It is produced by the strain of Cladosporium cladosporiodes. Cladosporin has the activity of weak resistance to gram-positive bacteria, tinea trichoderma, microspora, potato filaria and other fungi. Synonyms: 3,4-dihydro-6,8-dihydroxy-3-(6-methyltetrahydropyran-2-ylmethyl)isocoumarin; asperentin; cladosporin; isocladosporin. CAS No. 35818-31-6. Molecular formula: C16H20O5. Mole weight: 292.33.
Cladosporin
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL [1]. Uses: Scientific research. Group: Natural products. CAS No. 35818-31-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-136767.
Cladribine
Cladribine. Group: Biochemicals. Grades: Purified. CAS No. 4291-63-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Cladribine
Cladribine (2-Chloro-2-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Chloro-2-deoxyadenosine; CldAdo; 2CdA. CAS No. 4291-63-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13599.
Cladribine
2-Chloro-2'-deoxyadenosine is an analog of adenosine that is resistant to both proliferating and non-dividing lymphocytes (IC50 = 45 nM). When phosphorylated, 2-Chloro-2'-deoxyadenosine accumulates in cells and inhibits ribonucleotide reductase. Synonyms: 2-Chloro-2'-deoxyadenosine; Leustatine; 2-CdA; 9-(2'-Deoxy-β-D-ribofuranosyl)-2-chloro-adenine; 2-Chlorodeoxyadenosine; (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2-chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine. Grades: ≥95%. CAS No. 4291-63-8. Molecular formula: C10H12ClN5O3. Mole weight: 285.69.
It is a substituted purine nucleoside with antileukemic activity. Group: Biochemicals. Alternative Names: 2-Chloro-2-deoxyadenosine; 2-CdA; NSC-105014-F; Leustatin. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Cladribine 5'-Monophosphate Ammonium Salt
Cladribine 5'-Monophosphate Ammonium Salt can be used as an antiviral, antibacterial and antileukemic agent. Grades: 97%. Molecular formula: C10H16ClN6O6P. Mole weight: 382.7.
Cladribine Benzoate Impurity
Cladribine Benzoate Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152463-98-4. Molecular Formula: C18H18ClN5O4. Mole Weight: 403.82. Catalog: APB152463984.
Cladribine EP Impurity A
Cladribine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4546-70-7. Molecular Formula: C10H14N6O3. Mole Weight: 266.26. Catalog: APB4546707.
Cladribine EP Impurity B
Cladribine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 24757-70-8. Molecular Formula: C11H15N5O4. Mole Weight: 281.27. Catalog: APB24757708.
Cladribine EP Impurity C
Cladribine EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1839-18-5. Molecular Formula: C5H4ClN5. Mole Weight: 169.57. Catalog: APB1839185.
Cladribine EP Impurity D
Cladribine EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5542-92-7. Molecular Formula: C10H12ClN5O3. Mole Weight: 285.69. Catalog: APB5542927.
Cladribine EP Impurity E
Cladribine EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1831121-84-6. Molecular Formula: C5H10O4. Mole Weight: 134.13. Catalog: APB1831121846.
Cladribine EP Impurity E (Ring Opening)
Cladribine EP Impurity E (Ring Opening). Uses: For analytical and research use. Group: Impurity standards. CAS No. 533-67-5. Molecular Formula: C5H10O4. Mole Weight: 134.13. Catalog: APB533675.
Cladribine EP Impurity F
Cladribine EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 619-55-6. Molecular Formula: C8H9NO. Mole Weight: 135.17. Catalog: APB619556.
Cladribine EP Impurity G (Celecoxib Impurity 2)
Cladribine EP Impurity G (Celecoxib Impurity 2). Uses: For analytical and research use. Group: Impurity standards. CAS No. 99-75-2. Molecular Formula: C9H10O2. Mole Weight: 150.18. Catalog: APB99752.
Cladribine Impurity 1
Cladribine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 172792-37-9. Molecular Formula: C10H12ClN5O3. Mole Weight: 285.69. Catalog: APB172792379.
Cladribine Impurity 4
Cladribine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16373-93-6. Molecular Formula: C10H15N5O4. Mole Weight: 269.26. Catalog: APB16373936.
Cladribine Impurity D
1'-epi-Cladribine is an impurity of Cladribine, a substituted purine nucleoside with antileukemic activity. Synonyms: 1'-epi-Cladribine; 2-Chloro-9-(2-deoxy-α-D-erythro-pentofuranosyl)-adenine; 2-Chloro-6-amino-9-(2-deoxy-α-D-erythro-pentofuranosyl)purine; 2-Chloro-α-D-2'-deoxyadenosine; NSC 105013. Grades: > 95%. CAS No. 5542-92-7. Molecular formula: C10H12ClN5O3. Mole weight: 285.69.
Cladribine Impurity F
Cladribine Impurity F is an impurity of cladribine, a medication utilized for the therapy of hairy cell leukemia and multiple sclerosis. Synonyms: 4-Methylbenzamide; p-Toluamide. Grades: > 95%. CAS No. 619-55-6. Molecular formula: C8H9NO. Mole weight: 135.16.
Cladribine Impurity G
Methyl p-toluate is an impurity of 3-Toluoyl Decitabine, which is an intermediate of decitabine. It is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: Methyl p-Toluate; 4-(Methoxycarbonyl)toluene; 4-Methylbenzoic Acid Methyl Ester; Methyl 4-Methylbenzoate; Methyl 4-Toluate; Methyl p-Methylbenzoate; Methyl p-Toluate; Methyl p-Toluenecarboxylate; NSC 24761; p-(Methoxycarbonyl)toluene; p- Carbomethoxytolue. Grades: > 95%. CAS No. 99-75-2. Molecular formula: C9H10O2. Mole weight: 150.17.
Cladribine-Monophosphate sodium Salt
Cladribine-Monophosphate sodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104959-31-1. Molecular Formula: C10H12ClN5NaO6P. Mole Weight: 387.65. Catalog: APB104959311.
Cladribine Related Compound A
2-Methoxy-2'-deoxyadenosine is an impurity in the synthesis of Cladribine, a substituted purine nucleoside with antileukemic activity. Synonyms: 2-Methoxy-2'-deoxyadenosine; 2-Methoxy-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine; 9-(2-Deoxy-β-D-ribofuranosyl)-2-methoxyadenine; 2'-Deoxy-2-methoxyadenosine; (2R,3S,5R)-5-(6-Amino-2-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-Deoxyspongosine. Grades: ≥95%. CAS No. 24757-70-8. Molecular formula: C11H15N5O4. Mole weight: 281.27.
Cl-amidine
Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide. Grades: ≥95%. CAS No. 1043444-18-3. Molecular formula: C14H19ClN4O2·C2HF3O2. Mole weight: 424.8.
Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. Synonyms: N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide monohydrochloride. Grades: ≥95%. CAS No. 1373232-26-8. Molecular formula: C14H19ClN4O2·HCl. Mole weight: 347.24.
Clamikalant sodium
Clamikalant sodium (HMR 1098) is an ATP-sensitive potassium ( K ATP ) channel blocker. Clamikalant sodium can be used for the research of arrhythmia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMR 1098. CAS No. 261717-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15208.
Clamoxyquin Hydrochloride
Clamoxyquine, as the pamoate or hydrochloride salt, is an antiamebic and antidiarrheal drug used as a veterinary medicine to treat salmonids for infection with the myxozoan parasite Myxobolus cerebralis. Uses: Antiamebic and antidiarrheal. Synonyms: 5-chloro-7-[[3- (diethylamino) propylamino]methyl]quinolin-8-ol; dihydrochloride. Grades: ≥98%. CAS No. 4724-59-8. Molecular formula: C17H26Cl3N3O. Mole weight: 394.76.
Cl-ANT-ATP
Cl-ANT-ATP is an analogue of adenosine-5'-triphosphate, of which the intrinsic fluorescence would increase in hydrophobic environment. It can be used to study ATP-dependent receptor proteins. Synonyms: 2'- / 3'- O- (5- Chloroanthraniloyl)adenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1350521-45-7. Molecular formula: C17H20ClN6O14P3 (free acid). Mole weight: 660.8 (free acid).
Cl-ANT-ITP
Cl-ANT-ITP is an analogue of inosine-5'-triphosphate and an inhibitor of mammalian adenylate cyclases, of which the intrinsic fluorescence would increase in hydrophobic environment. Synonyms: 2'- / 3'- O- (5- Chloroanthraniloyl)inosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1350521-48-0. Molecular formula: C17H19ClN5O15P3 (free acid). Mole weight: 661.7 (free acid).
Clarithromycin
Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM. Clarithromycin significantly inhibits the HERG potassium current.Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Erythromycin, 6-O-methyl-. Product Category: Inhibitors. CAS No. 81103-11-9. Molecular formula: C38H69NO13. Mole weight: 747.95. Purity: 0.999. Product ID: ACM81103119-1. Alfa Chemistry ISO 9001:2015 Certified.
Clarithromycin
Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4 -catalyzed triazolam alpha-hydroxylation with the IC 50 ( K i ) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-17508.
Clarithromycin
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C38H69NO13. CAS No. 81103-11-9. Prepack ID 37077446-1g. Molecular Weight 747.95. See USA prepack pricing.
Clarithromycin
Clarithromycin. Group: Biochemicals. Alternative Names: 6-O-Methylerythromycin, A-56268, TE-031, biaxin. Grades: Highly Purified. CAS No. 81103-11-9. Pack Sizes: 1g, 5g, 10g, 25g, 50g. Molecular Formula: C38H69NO13, Water: ≤2%. US Biological Life Sciences.