A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
It is produced by the strain of semisynthetic isoxazole penicillin. Cloxacillin is a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. It is a chlorinated derivative of oxacillin and is an antibiotic useful for the treatment of a number of bacterial infections. It binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thus preventing the cross-linkage of peptidoglycans, which leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. It is used against staphylococci that produce beta-lactamase, due to its large R chain, which does not allow the beta-lactamases to bind. It was discovered and developed by Beecham. Uses: Cloxacillin is an antibiotic useful for the treatment of a number of bacterial infections. Synonyms: Cloxacillinum; Cloxacilina; Syntarpen; Tegopen; (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin. Grade: 98%. CAS No. 61-72-3. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
Cloxacillin benzathine
Cloxacillin benzathine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CLOXACILLIN BENZATHINE;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2alpha,5alpha,6beta)]-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1);microst. Product Category: Heterocyclic Organic Compound. CAS No. 23736-58-5. Molecular formula: 2(C19H18ClN3O5S).C16H20N2. Mole weight: 1112.11. Density: 1.56g/cm³. Product ID: ACM23736585. Alfa Chemistry ISO 9001:2015 Certified.
Cloxacillin EP Impurity D
3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid is used in the preparation of isoxazolecarboxamides as a class of TGR5 agonists. It is also used in the preparation of β-lactamase inhibitors. Synonyms: 3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid. Grade: > 95%. CAS No. 23598-72-3. Molecular formula: C11H8ClNO3. Mole weight: 237.64.
Cloxacillin Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Cloxacillin sodium
Cloxacillin sodium is an orally active antibacterial agent and β-lactamase inhibitor with an IC 50 of 0.04 μM. Cloxacillin sodium can suppress the S. aureus -induced inflammatory response by inhibiting the activation of MAPKs , NF-?B and NLRP3 -related proteins [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 642-78-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0466B.
Cloxacillin Sodium
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: 3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl penicillin sodium salt monohydrate, Sodium cloxacillin monohydrate, Oxacillin Imp. E (EP), 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S,5R,6R)- (9CI),Oxacillin Sodium Imp. E (EP), Cloxacillin Sodium Monohydrate, Oxacillin Sodium Imp. E (EP) as Sodium Salt Monohydrate, 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate (8CI), 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, [2S-(2alpha,5alpha,6beta)]-, Sodium 6-[3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate.
Cloxacillin Sodium EP Impurity B (Mixture of Diastereomers)
Cloxacillin Sodium EP Impurity B (Mixture of Diastereomers) is a an impurity of Cloxacillin Sodium, an antibiotic medication for treating bacterial infections. Synonyms: 2-[[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid. Grade: > 95%. CAS No. 1642559-64-5. Molecular formula: C18H19ClN3O4S. Mole weight: 408.89.
Cloxacillin Sodium EP Impurity E
Cloxacillin Sodium EP Impurity E is an impurity of Cloxacillin Sodium, having primary application towards treating bacterial infections orchestrated by susceptible organisms. Grade: > 95%. CAS No. 18704-55-7. Molecular formula: C27H27ClN5O7S2. Mole weight: 633.13.
Cloxacillin sodium ≥825mg/mg
Cloxacillin sodium ≥825mg/mg. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Cloxacillin sodium monohydrate
Cloxacillin sodium monohydrate is an orally active antibacterial agent and β-lactamase inhibitor with an IC 50 of 0.04 μM. Cloxacillin sodium monohydrate can suppress the S. aureus -induced inflammatory response by inhibiting the activation of MAPKs , NF-?B and NLRP3 -related proteins [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7081-44-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0466.
Cloxacillin Sodium Monohydrate
Cloxacillin Sodium Monohydrate is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin. Uses: Anti-bacterial agents. Synonyms: Cloxapen. Grade: >98%. CAS No. 7081-44-9. Molecular formula: C19H19ClN3NaO6S. Mole weight: 475.88.
Cloxacillin sodium salt
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C19H17ClN3NaO5S. CAS No. 642-78-4. Prepack ID 12372159-1g. Molecular Weight 475.86. See USA prepack pricing.
Cloxacillin Sodium Salt
Cloxacillin is an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding. Synonyms: (2S,5R,6R)-6-[[[3-(2-Chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium Salt; Ankerbin; 3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin Sodium Salt; Austrastaph; BRL 1621 So. Grade: > 95%. CAS No. 642-78-4. Molecular formula: C19H17ClN3O5SNa. Mole weight: 457.86.
Cloxacillin sodium salt monohydrate
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H17ClN3O5SNa · H2O. CAS No. 7081-44-9. Prepack ID 90025568-1g. Molecular Weight 475.88. See USA prepack pricing.
Cloxacillin sodium salt monohydrate
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H17ClN3O5SNa · H2O. CAS No. 7081-44-9. Prepack ID 90025568-5g. Molecular Weight 475.88. See USA prepack pricing.
Cloxicillin Benzathine
Cloxicillin Benzathine - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Cloxicillin Sodium
Cloxicillin Sodium - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Cloxyfonac
Cloxyfonac is a plant growth regulator and a chemical transformation product. Synonyms: Cloxyfonac; 6386-63-6; Clocxyfonac; 2-(4-Chloro-2-(hydroxymethyl)phenoxy)acetic acid2-[4-chloro-2-(hydroxymethyl)phenoxy]acetic acid. Grade: >98%. CAS No. 6386-63-6. Molecular formula: C9H9ClO4. Mole weight: 216.62.
Clozapine is an Atypical Antipsychotic. Alternative Names: Leponex. Clozapin. Fazaclo. CAS No. 5786-21-0. Product ID: API5786210. Molecular formula: C18H19ClN4. Mole weight: 326.8. EINECS: 227-313-7. SMILES: CN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42. Appearance: Yellow crystals. Category: Antipsychotic APIs.
Clozapine
Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively [1] [2] [3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HF 1854. CAS No. 5786-21-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14539.
Clozapine
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C18H19ClN4. CAS No. 5786-21-0. Prepack ID 66826682-25mg. Molecular Weight 326.82. See USA prepack pricing.
Clozapine-d4
Clozapine-d 4 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: HF 1854-d4. CAS No. 204395-52-8. Pack Sizes: 1 mg. Product ID: HY-14539S2.
An antipsychotic.A representative lot was 92% d8, 8% d7. Group: Biochemicals. Alternative Names: 8-Chloro-11-(4-methyl-1-piperazinyl-d8)-5H-dibenzo[b, e][1, 4]diazepine; HF-1854-d8; Liponex-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Clozapine Impurity 6
Clozapine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025951-76-1. Molecular formula: C20H21ClN4O. Mole weight: 368.86. Catalog: APB1025951761.
Clozapine N-oxide
Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34233-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366.
Clozapine N-oxide dihydrochloride
Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250025-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366A.
Clozapine (Standard)
Clozapine (Standard) is the analytical standard of Clozapine. This product is intended for research and analytical applications. Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively [1] [2] [3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HF 1854 (Standard). CAS No. 5786-21-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14539R.
CLP257
CLP257 is a selective K+-Cl cotransporter KCC2 activator with an EC50 of 616 nM. CLP257 is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 restores impaired Cl transport in neurons with diminished KCC2 activity. CLP257 alleviates hypersensitivity in rats with neuropathic pain. CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181081-71-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110143.
CLP 257. Group: Biochemicals. Grades: Purified. CAS No. 1181081-71-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CLP 257
CLP 257 has been found to be a KCC2 K+-Cl- cotransporter activator and could alleviates hypersensitivity in rats with peripheral nerve injury. Synonyms: CLP 257; CLP-257; CLP257; (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone. Grade: ≥98% by HPLC. CAS No. 1181081-71-9. Molecular formula: C14H14FN3O2S. Mole weight: 307.34.
CLP290 is an orally available activator of the neuron-specific K+-Cl- cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181083-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103023.
CLP-3094
CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). It inhibits AR transcriptional activity (IC50 = 4 μM). CLP-3094 is also a selective, potent GPR142 antagonist. Synonyms: 2-{[2-(4-Chlorophenoxy)ethyl]thio}-1H-benzimidazole; 1H-Benzimidazole, 2-[[2-(4-chlorophenoxy)ethyl]thio]-. Grade: ≥95%. CAS No. 312749-73-8. Molecular formula: C15H13ClN2OS. Mole weight: 304.79.
Cl-PEG4-acid
Cl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 158553-98-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W096129.
CLPP (240-248)
CLPP is a protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. It has low peptidase activity in the absence of CLPX. Synonyms: Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit (240-248); ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial (240-248).
CLS-011A
CLS-011A is a small molecule used as an antineoplastic and eye disorder therapy. Study indicated its excellent tolerance. Uses: Antineoplastic and eye disorder therapy. Synonyms: CLS 011A.
Cl--transporting ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. An animal and plant enzyme involved in the import of chloride anions. Group: Enzymes. Synonyms: Cl--translocating ATPase; Cl--motive ATPase. Enzyme Commission Number: EC 3.6.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4648; Cl--transporting ATPase; EC 3.6.3.11; Cl--translocating ATPase; Cl--motive ATPase. Cat No: EXWM-4648.
Cl-Trt-Resin
Cl-Trt-Resin. Synonyms: Tritylchloride Resin.
Cluster Dextrin
Cluster Dextrin.
CA, FL & NJ
Clusterin (nuclear form) mouse
recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
CLZ-8
CLZ-8 (Compound 8) is an orally active Mcl-1-PUMA interface inhibitor, with a K i of 0.3 μM. CLZ-8 exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 678158-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122627.
CM03
CM03 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2101208-44-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121862.
CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grade: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34.
CM 10
CM 10 is an inhibitor of aldehyde dehydrogenase 1A (ALDH1A) inhibitor. It can induce a necroptotic phenotype and preferentially deplete CD133+ ovarian cancer stem cells in vitro. Synonyms: 2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol. Grade: ≥98% by HPLC. CAS No. 692269-09-3. Molecular formula: C20H23N3O. Mole weight: 321.42.
CM-24
CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1783801-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990569.
CM-272
CM-272 is a first-in-class reversible and substrate-competitive dual inhibitor of G9a (GLP) and DNMTs. CM-272 inhibits cell proliferation and promotes apoptosis, inducing interferon-stimulated genes and immunogenic cell death in models of haematological neoplasia. Synonyms: CM 272; CM272. CAS No. 1846570-31-7. Molecular formula: C28H38N4O3. Mole weight: 478.63.
CM-272
CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1846570-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101925.
CM-3
CM-3 is a synthetic construct with antibacterial activity.
CM-352
CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function. Synonyms: CM352; CM 352; CM-352; (R)-N-hydroxy-2-((4-(4-(methylcarbamoyl)phenoxy)phenyl)sulfonyl)-8-azaspiro[4.5]decane-2-carboxamide. Grade: 98%. CAS No. 1542205-83-3. Molecular formula: C24H29N3O6S. Mole weight: 487.57.
CM398
CM398 has preferential affinity for sigma-2 receptor compared with sigma-1 receptor and at least four other neurotransmitter receptors sites, including the norepinephrine transporter. Synonyms: 1-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1h)-yl)butyl)-3-methyl-1h-benzo[d]imidazol-2(3h)-one. Grade: 98%. CAS No. 1121931-70-1. Molecular formula: C23H29N3O3. Mole weight: 395.49.
CM398
CM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1121931-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145628.
CM-579 trihydrochloride
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT, with IC50s of 16 nM and 32 nM, respectively. It has potent in vitro cellular activity in a wide range of cancer cells. Synonyms: 6-Methoxy-2-(5-methyl-2-furyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinolinamine trihydrochloride; 4-Quinolinamine, 6-methoxy-2-(5-methyl-2-furanyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrochloride (1:3). Grade: ≥95%. Molecular formula: C29H43Cl3N4O3. Mole weight: 602.04.
CMA
CMA is a murine-selective agonist of STING. It triggers type I IFN response in murine macrophages, without effect on human STING signaling. Synonyms: 9-Oxo-10(9H)-acridineacetic acid. Grade: ≥98% by HPLC. CAS No. 38609-97-1. Molecular formula: C15H11NO3. Mole weight: 253.25.
CMC2.24
CMC2.24 is an orally active tricarbonylmethane agent. It is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 μM. Synonyms: TRB-N0224. Grade: 96%. CAS No. 1255639-43-0. Molecular formula: C26H21NO5. Mole weight: 427.45.
CMC-Na
CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. CAS No. 9004-32-4. Product ID: PE-0150. Category: Binder Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Binder Excipients; CMC-Na; PE-0150; 9004-32-4; 9004-32-4. Purity: 0.9972. Synonym(s): Sodium carboxymethyl cellulose. Storage: 3 years -20°C powder.
CMD178
CMD178 is a lead peptide that can sustainably reduce the expression of Foxp3 and STAT5 induced by IL-2/ S IL-2Rα signal. CMD178 is also a STAT5 inhibitor and inhibits the development of Treg cells. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester; RFKFY-OBn; CMD 178; CMD-178. Grade: ≥98%. CAS No. 2703745-80-4. Molecular formula: C46H59N9O7. Mole weight: 850.03.
CMD178 TFA
CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grade: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05.
CM-Dextran sodium salt
CM-Dextran sodium salt. Group: Natural polymers and biopolymerspolysaccharide. CAS No. 39422-83-8.
c-Met-IN-1, a potent and selective c-Met inhibitor (IC50 = 1.1 nM), has antitumor activity. Synonyms: N-[3-Fluoro-4-[6-methoxy-7-[3-(4-methylpiperazino)propoxy]quinoline-4-yloxy]phenyl]-1-(2-methoxyphenyl)-1H-imidazole-4-carboxamide; 1H-Imidazole-4-carboxamide, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-4-quinolinyl]oxy]phenyl]-1-(2-methoxyphenyl)-. Grade: ≥95%. CAS No. 2084836-84-8. Molecular formula: C35H37FN6O5. Mole weight: 640.70.
c-Met-IN-2
c-Met-IN-2, a potent, selective and orally available c-Met inhibitor (IC50 = 0.6 nM), has antitumor activity. Synonyms: 2-[4-(1-{1-[7-Fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl}-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl]ethanol; 1H-Pyrazole-1-ethanol, 4-[1-[1-[7-fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl]-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-. Grade: ≥95%. CAS No. 1635406-73-3. Molecular formula: C24H21FN10O. Mole weight: 484.49.
c-Met inhibitor 1
c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grade: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41.
c-Met Kinase Inhibitor III
The c-Met Kinase Inhibitor III controls the biological activity of c-Met. Group: Fluorescence/luminescence spectroscopy.