A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CU-CPT-9b is a TLR8 inhibitor that inhibits TLR8-mediated proinflammatory signaling in various cell lines and human primary cells. Synonyms: CU-CPT9a; 2-Methyl-4-(7-methoxy-4-quinolinyl)phenol; CU CPT 9a; BCP29122; BCP-29122; CUCPT9a; BCP 29122; 4-(7-methoxy-1H-quinolin-4-ylidene)-2-methylcyclohexa-2,5-dien-1-one; Phenol, 4-(7-methoxy-4-quinolinyl)-2-methyl-; 4-(7-Methoxy-4-quinolinyl)-2-methylphenol. Grades: ≥95%. CAS No. 2165340-32-7. Molecular formula: C17H15NO2. Mole weight: 265.31.
CuCrZr High-Entropy Alloy Ingots
We are engaged in the development, production, and sales of CuCrZr High-Entropy Alloy Ingots and provide personalized customization service for high-quality metal powder. CuCrZr High-Entropy Alloy is a new alloy with very unique properties. Uses: Used in manufacturing super alloys and electron-beam melting. used in metallurgical, machinery processing, glass, and ceramic industries. used in electronics industry, such as integrated circuits. used in the field of glass coating. Group: High entropy alloys. Pack Sizes: Our CuCrZr High-Entropy Alloy Ingot is carefully handled during storage and transportation to preserve the quality of our product in its original condition. 0.99.
CuCrZr High-Entropy Alloy Spherical Powder
We are engaged in the development, production and sales of CuCrZr high entropy alloy spherical powder, and provide personalized service for high quality metal powder. CuCrZr high entropy alloy spherical powder is a new type of alloy with very unique properties. Uses: Cucrzr high-entropy alloy spherical powder is widely used in aerospace parts and auto parts, profile surface spraying, powder metallurgy, nuclear energy and industrial fields. Group: High entropy alloys.
Cucumber Powder
Cucumber powder is made from Cucumis sativus, a widely cultivated plant in the gourd family Cucurbitaceae. Cucumber powder is a great ingredient to help revitalize the skin. Cucumber powder has many benefits for skin, it helps relieve the puffiness of the skin. Cucumber powder also helps remove dead skin cells and tightens skin. Group: Others. Cucumber Powder; Cucumis Sativus Linn. Cat No: EXTC-106.
cucumisin
From the sarcocarp of the musk melon (Cucumis melo). In peptidase family S8 (subtilisin family). Other endopeptidases from plants, which are less well characterized but presumably of serine-type, include euphorbain from Euphorbia cerifera, solanain from horse-nettle Solanum elaeagnifolium, hurain from Hura crepitans and tabernamontanain from Tabernamontana grandiflora. Group: Enzymes. Synonyms: euphorbain; solanain; hurain; tabernamontanain. Enzyme Commission Number: EC 3.4.21.25. CAS No. 82062-89-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4123; cucumisin; EC 3.4.21.25; 82062-89-3; euphorbain; solanain; hurain; tabernamontanain. Cat No: EXWM-4123.
Cucurbit[5]uril hydrate
Cucurbiturils are macrocyclic molecules made of glycoluril monomers linked by methylene bridges. The oxygen atoms are located along the edges of the band and are tilted inwards, forming a partly enclosed cavity. Cucurbiturils are commonly written as cucurbit[n]uril, where n is the number of glycoluril units. Two common abbreviations are CB[n], or simply CBn. Uses: Host material for supramolecular chemistry. Group: Hydrophilic polymers. Pack Sizes: Packaging 100 mg in glass insert. Mole weight: C30H30N20O10 · xH2O · xKCl · xHCl. O. Cl. [Cl-]. [K+]. O=C1N2CN3C4C5N (CN6C7C8N (CN9C%10C%11N (CN%12C%13C%14N (CN1C%15C2N%16CN4C (=O) N5CN7C (=O) N8CN%10C (=O) N%11CN%13C (=O) N%14CN%15C%16=O) C%12=O) C9=O) C6=O) C3=O. 1S/C30H30N20O10. 2ClH. K. H2O/c51-21-31-1-32-12-14-36 (22 (32)52)4-40-16-18-44 (26 (40)56)8-48-20-19-47 (29 (48)59)7-43-17-15-39 (25 (43)55)3-35 (21)13-11 (31)33-2-34 (12)24 (54)38 (14)6-42 (16)28 (58)46 (18)10-50 (20)30 (60)49 (19)9-45 (17)27 (57)41 (15)5-37 (13)23 (33)53; ; ; ; /h11-20H, 1-10H2; 2*1H; ; 1H2/q; ; ; +1; /p-1/t11-, 12+, 13+, 14-, 15-, 16+, 17+, 18-, 19-, 20+; ; ;. VIWLZIOPOSWHFW-DVJLYPCZSA-M.
Cucurbit[7]uril is a cyclic organic molecule that consists of seven glycoluril units connected by methylene bridges. Cucurbit[7]uril is a pharmaceutical excipient, which can be used in the fields of drug delivery, catalysis, and sensing. Synonyms: 2, 18:3, 17-Dimethano-2, 3, 4a, 5a, 6a, 7a, 8a, 9a, 10a, 11a, 12a, 13a, 14a, 15a, 17, 18, 19a, 20a, 21a, 22a, 23a, 24a, 25a, 26a, 27a, 28a, 29a, 30a-octacosaazabispentaleno[1''''', 6''''':5'''', 6'''', 7'''']cycloocta[1'''', 2'''', 3'''':3''', 4''']pentaleno[1''', 6''':5'', 6'', 7'']cycloocta[1'', 2'', 3'':3', 4']pentaleno[1', 6':5, 6, 7]cycloocta[1, 2, 3-cd:1', 2', 3'-gh]pentalene-1, 4, 6, 8, 10, 12, 14, 16, 19, 21, 23, 25, 27, 29-tetradecone, tetradecahydro-, stereoisomer; stereoisomer of Tetradecahydro-2, 18:3, 17-dimethano-2, 3, 4a, 5a, 6a, 7a, 8a, 9a, 10a, 11a, 12a, 13a, 14a, 15a, 17, 18, 19a, 20a, 21a, 22a, 23a, 24a, 25a, 26a, 27a, 28a, 29a, 30a-octacosaazabispentaleno[1''''', 6''''':5'''', 6'''', 7'''']cycloocta[1'''', 2'''', 3'''':3''', 4''']pentaleno[1''', 6''':5'', 6'', 7'']cycloocta[1'', 2'', 3'':3', 4']pentaleno[1', 6':5, 6, 7]cycloocta[1, 2, 3-cd:1', 2', 3'-gh]pentalene-1, 4, 6, 8, 10, 12, 14, 16, 19, 21, 23, 25, 27, 29-tetradecone; Carrier CB 7; CB 7; CB-7; CB7. Grades: 95%. CAS No. 259886-50-5. Molecular formula: C42H42N28O14. Mole weight: 1162.96.
Cucurbit[7]uril
Cucurbit[7]uril is a cyclic organic molecule consisting of seven glycoluril units linked by methylene bridges. It has a rigid barrel-like structure with two identical inlets at both ends to selectively encapsulate guest molecules of appropriate size, shape, and polarity. Cucurbit[7]uril is known for its high binding affinity for a variety of organic and inorganic guests, including drugs, amino acids, peptides, and metal ions. This property makes them promising candidates for various applications in areas such as drug delivery, catalysis, and sensing. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CB7; Carrier CB7. CAS No. 259886-50-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-104086.
Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy transfer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 259886-51-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103689.
Cucurbit[8]uril
Cucurbit[8]uril is a remarkably versatile host molecule utilized in a diverse range of drug delivery and catalysis applications. Its unique ability to selectively bind various drug and biomolecule targets with high avidity illustrates its significant potential as a candidate for targeted drug delivery. Furthermore, the catalytic efficacy and promising sensor properties of Cucurbit[8]uril make it a valuable asset in the field of chemical synthesis and detection of diverse analytes. Synonyms: CB[8]; Cucurubituril(8). Grades: 95%. CAS No. 259886-51-6. Molecular formula: C48H48N32O16. Mole weight: 1329.10.
Cucurbit[8]uril hydrate
Cucurbiturils are macrocyclic molecules made of glycoluril monomers linked by methylene bridges. The oxygen atoms are located along the edges of the band and are tilted inwards, forming a partly enclosed cavity. Cucurbiturils are commonly written as cucurbit[n]uril, where n is the number of glycoluril units. Two common abbreviations are CB[n], or simply CBn. Uses: Chemists have used cucurbituril for a variety of applications, including drug delivery, asymmetric synthesis, molecular switching, and dye tuning. Group: Hydrophilic polymers. Pack Sizes: Packaging 100 mg in glass insert. Product ID: 3, 5, 8, 10, 13, 15, 18, 20, 23, 25, 28, 30, 33, 35, 38, 40, 41, 43, 45, 47, 51, 53, 55, 57, 59, 61, 63, 65, 67, 69, 71, 73-dotriacontazapentacosacyclo[35. 3. 3. 36, 7. 311, 12. 316, 17. 321, 22. 326, 27. 331, 32. 22, 41. 236, 43. 13, 40. 15, 8. 110, 13. 115, 18. 120, 23. 125, 28. 130, 33. 135, 38. 145, 51. 147, 73. 153, 55. 157, 59. 161, 63. 165, 67. 169, 71]octacontane-44, 46, 48, 49, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72-hexadecone; hydrate. Molecular formula: 1347.1g/mol. Mole weight: C48H48N32O16 · xH2O · xHCl. O. Cl. O=C1N2CN3C4C5N (CN6C7C8N (CN9C%10C%11N (CN%12C%13C%14N (CN%15C%16C%17N (CN%18C%19C%20N (CN%21C%22C%23N (CN1C%24C2N%25CN4C (=O) N5CN7C (=O) N8CN%10C (=O) N%11CN%13C (=O) N%14CN%16C (=O) N%17CN%19C (=O) N%20CN%22C (=O) N%23CN%24C%25=O) C%21=O) C%18=O) C%15=O) C%12=O) C9=O) C6=O) C3=O. 1S/C48H48N32O1
Cucurbitacin
Cucurbitacin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2222-7-3. Molecular Formula: C30H42O7. Mole Weight: 514.66. Catalog: APB2222073.
Cucurbitacin A
Cucurbitacin A. Group: Biochemicals. CAS No. 6040-19-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cucurbitacin A
Cucurbitacin A is a triterpenoid sterol isolated from rhizomes of Hemsleya amabilis Diels. Synonyms: Cucurbitacin A; 6040-19-3; UNII-83859; MTO77NSC94743; CHEBI:3940. Grades: >98%. CAS No. 6040-19-3. Molecular formula: C32H46O9. Mole weight: 574.711.
Cucurbitacin B
Cucurbitacin B. Group: Biochemicals. Alternative Names: Amarin. Grades: Plant Grade. CAS No. 6199-67-3. Pack Sizes: 20mg. Molecular Formula: C32H46O8, Molecular Weight: 558.703. US Biological Life Sciences.
Worldwide
Cucurbitacin B
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 6199-67-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0416.
Cucurbitacin B
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids; could repress cancer cell progression.IC50 value:Target: anticancer natural compoundin vitro: Cucurbitacin-B inhibited growth and modulated expression of cell-cycle regulators in SHSY5Y cells. At the molecular level, we found that Cucurbitacin-B inhibited AKT signaling activation through up-regulation of PTEN. CuB induced apoptosis of A549 cells in a -concentration-dependent manner, as determined by fluorescence microscopy, flow cytometry and transmission electron microscopy. CuB dose-dependently inhibited lung cancer cell proliferation, with cell cycle inhibition and cyclin B1 downregulation. Apoptosis induced by CuB was shown to be associated with cytochrome c release, B-cell lymphoma 2 downregulation and signal transducer and activator of transcription 3 pathway inhibition. CuB inhibited ITGA6 and ITGB4 (integrin α6 and integrin β4), which are overexpressed in breast cancer. Furthermore, CuB also induced the expression of major ITGB1and ITGB3, which are known to cause integrin-mediated cell death. Cuc B treatment caused DNA double-strand breaks (DSBs) without affecting the signal transducer and activator of transcription 3 (STAT3), the potential molecular target for Cuc B. Cuc B triggers ATM-activated Chk1-Cdc25C-Cdk1, which could be reversed by both ATM siRNA and Chk1 siRNA. Cuc B also triggers ATM-activated p53-14-3-3-σ pa
Cucurbitacin C
Cucurbitacin C is a cucurbitacin. Grades: > 95%. CAS No. 5988-76-1. Molecular formula: C32H48O8. Mole weight: 560.72.
Cucurbitacin D
Cucurbitacin D. Group: Biochemicals. CAS No. 3877-86-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cucurbitacin D
Source from rhizomes of Hemsleya amabilis Diels. It might be a new therapeutic option for the treatment of endometrial and ovarian cancers, also may be a potential therapeutic agent for β-hemoglobinopathies, including sickle cell anemia and β-thalassemia. And it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. Uses: Antitumor, resistance to chemical carcinogens, protect liver. Synonyms: 17-[(3E)-1,5-Dihydroxy-1,5-dimethyl-2-oxohex-3-en-1-yl]-2,16-dihydroxy-4,4,9,14-tetramethylestr-5-ene-3,11-dione. Grades: >98%. CAS No. 3877-86-9. Molecular formula: C30H44O7. Mole weight: 516.67.
Cucurbitacin D
Cucurbitacin D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3877-86-9. Molecular Formula: C30H44O7. Mole Weight: 516.68. Catalog: APB3877869.
Cucurbitacin D
Cucurbitacin D is the active ingredient in Trichosanthes kirilowii and can disrupt the interaction between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D is an inflammasome activator. Cucurbitacin D induces cell cycle arrest and cell apoptosis , exhibiting anti-tumor and anti-inflammatory effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 3877-86-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1986.
cucurbitacin Δ23-reductase
Requires Mn2+. Fe2+ or Zn2+ can replace Mn2+ to some extent. Group: Enzymes. Synonyms: NAD(P)H: cucurbitacin B Δ23-oxidoreductase. Enzyme Commission Number: EC 1.3.1.5. CAS No. 37256-38-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1322; cucurbitacin Δ23-reductase; EC 1.3.1.5; 37256-38-5; NAD(P)H: cucurbitacin B Δ23-oxidoreductase. Cat No: EXWM-1322.
Cucurbitacin E
Cucurbitacin E. Group: Biochemicals. Alternative Names: Cucurbitacine E; NSC 106399; NSC 521775; α-Elaterin; α-Elaterine; 2,16α,20,25-Tetrahydroxy-9-methyl-19-Nor-9 β,10α-lanosta-1,5,23-triene-3,11,22-trione 25-Acetate. Grades: Highly Purified. CAS No. 18444-66-1. Pack Sizes: 1mg. Molecular Formula: C32H44O8, Molecular Weight: 556.69. US Biological Life Sciences.
Worldwide
Cucurbitacin E
Cucurbitacin E is a natural compound which from Cucurbitaceae plants. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White powder. CAS No. 18444-66-1. Molecular formula: C32H44O8. Mole weight: 556.67. Purity: 0.98. IUPACName: [(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate. Canonical SMILES: CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3C=C(C(=O)C4(C)C)O)C)C)C)O)O. Product ID: ACM18444661. Alfa Chemistry ISO 9001:2015 Certified.
Cucurbitacin E 2-O-glucoside
Cucurbitacin E 2-O-glucoside. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1398-78-3. Molecular Formula: C38H54O13. Mole Weight: 718.84. Catalog: APB1398783.
Cucurbitacin I
Cucurbitacin I is a natural selective inhibitor of JAK2/STAT3, with potent anti-cancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cucurbitacin I. Product Category: Inhibitors. Appearance: White solid. CAS No. 2222-7-3. Molecular formula: C30H42O7. Mole weight: 514.65. Purity: 0.98. Density: 1.26g/cm³. Product ID: ACM2222073. Alfa Chemistry ISO 9001:2015 Certified.
Cucurbitacin I
Cucurbitacin I. Group: Biochemicals. Grades: Purified. CAS No. 2222-7-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cucurbitacin I
Cucurbitacin I is a triterpenoid compound which is extracted from some Cucurbitaceae related plants. It was found to be a potential selective inhibitor of JAK2 / STAT3 showing various of possible Pharmacological activities.(IC50 = 500 nM when suppresses l. Uses: Cucurbitacin i is a triterpenoid compound and has been found to be a potential selective inhibitor of jak2 / stat3. Synonyms: Cucurbitacin I; Elatericin B; Cucurbitacine (I); 1,2-Dehydroelatericin A; CHEBI:3947. Grades: ≥95%. CAS No. 2222-7-3. Molecular formula: C30H42O7. Mole weight: 514.65.
Cucurbitacin Iia
Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White powder. CAS No. 58546-34-2. Molecular formula: C32H50O8. Mole weight: 562.73. Purity: 0.98. IUPACName: [(6R)-6-hydroxy-2-methyl-5-oxo-6-[(2S,3S,8S,9R,10R,13R,14S,16R,17R)-2,3,16-trihydroxy-4,4,9,13,14-pentamethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]heptan-2-yl] acetate. Canonical SMILES: CC(=O)OC(C)(C)CCC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(C4(C)C)O)O)C)C)C)O)O. Product ID: ACM58546342. Alfa Chemistry ISO 9001:2015 Certified. Categories: Hemslecin A.
Cucurbitacin IIa
Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin , reduces phospho-Histone H3 and increases cleaved PARP in cancer cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Hemslecin A. CAS No. 58546-34-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N1988.
Cucurbitacin IIb
Cucurbitacin IIb. Group: Biochemicals. Alternative Names: 23,24-Dihydrocucurbitacin F. Grades: Plant Grade. CAS No. 50298-90-3. Pack Sizes: 10mg. Molecular Formula: C30H48O7, Molecular Weight: 520.698. US Biological Life Sciences.
Worldwide
Cucurbitacin impurity 1
Cucurbitacin impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 17278-28-3. Molecular Formula: C32H46O8. Mole Weight: 558.71. Catalog: APB17278283.
Cucurbitacin impurity 2
Cucurbitacin impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 65247-27-0. Molecular Formula: C38H56O13. Mole Weight: 720.85. Catalog: APB65247270.
Cucurbitacin impurity 3
Cucurbitacin impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1110-02-7. Molecular Formula: C30H44O7. Mole Weight: 516.68. Catalog: APB1110027.
Cucurbitacin Q1
Cucurbitacin Q1 is a terpenoid isolated from hemsleya amabilis. Synonyms: 25-acetylcucurbitacin F; 25-O-Acetylcucurbitacin F. Grades: 0.98. CAS No. 99530-82-2. Molecular formula: C32H48O8. Mole weight: 560.7.
Cucurbitacin S
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 60137-06-6. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
Worldwide
cucurbitadienol synthase
This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. Group: Enzymes. Synonyms: CPQ (gene name); (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming). Enzyme Commission Number: EC 5.4.99.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5574; cucurbitadienol synthase; EC 5.4.99.33; CPQ (gene name); (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming). Cat No: EXWM-5574.
Cucurbituril
Cucurbituril is a container molecule resembling a hollow pumpkin, with two identical inlets at each end and a hydrophobic cavity in the middle. Cucurbiturils have unique chemical properties that allow them to selectively encapsulate guest molecules such as drugs or catalysts within their cavities, shielding them from the surrounding environment. Cucurbituril has important potential applications in various fields such as drug delivery, catalysis and materials science. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 80262-44-8. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-W130354.
Cucurmoschin is an antifungal peptide isolated from Cucurbita maxima. Synonyms: Pro-Gln-Arg-Gly-Glu-Gly-Gly-Arg-Ala-Gly-Asn-Leu-Leu-Arg-Glu-Glu-Gln-Glu-Ile. Grades: 95.3%. Molecular formula: C86H145N31O31. Mole weight: 2109.29.
CUDA
CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH) , with IC 50 s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively [1]. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 479413-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121538.
CUDA
CUDA is an inhibitor of soluble epoxide hydrolase (sEH) which catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids (DiHETrEs; DHETs) thereby diminishing their activity with IC50 values of 11.1 nM and 112 nM for the mouse and human enzymes, respectively. Synonyms: 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid. Grades: ≥95%. CAS No. 479413-68-8. Molecular formula: C19H36N2O3. Mole weight: 340.5.
CUDC-101
CUDC-101 is a multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor tyrosine kinase (EGFR/ErbB1), and human epidermal growth factor receptor 2 tyrosine kinase (HER2/neu or ErbB2) with potential antineoplastic activity. HDAC/EGFR/HER2 inhibitor CUDC-101 inhibits the activity of these three enzymes but the exact mechanism of action is presently unknown. This agent may help overcome resistance to inhibition of EGFR and Her2 through a simultaneous, synergistic inhibition of EGFR, Her2, and HDAC. Synonyms: CUDC101; CUDC 101; CUDC-101. CAS No. 1012054-59-9. Molecular formula: C24H26N4O4. Mole weight: 434.496.
CUDC-101
CUDC-101 is a potent inhibitor of HDAC , EGFR , and HER2 with IC 50 s of 4.4, 2.4, and 15.7 nM, respectively. CUDC-101 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1012054-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10223.
CUDC-101
CUDC-101 is a potent multi-acting HDAC (histone deacetylase), EGFR (epidermal growth factor receptor), and HER2 ( human epidermal growth factor receptor 2) inhibitor for the treatment of cancer. Group: Biochemicals. Alternative Names: 7-[[4-[(3-Ethynylphenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanamide; 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide. Grades: Highly Purified. CAS No. 1012054-59-9. Pack Sizes: 10mg. US Biological Life Sciences.
A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC?? values of 4.4, 2.4, and 15.7nm, respectively. Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 1012054-59-9. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
CUDC-907
CUDC-907 is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types. This may prevent growth of PI3K and/or HDAC-expressing tumor cells. CUDC-907 shows an increased inhibition of tumor cell growth and induction of apoptosis when compared to inhibitors that target either PI3K or HDAC. Synonyms: CUDC907; CUDC 907; CUDC-907. CAS No. 1339928-25-4. Molecular formula: C23H24N8O4S. Mole weight: 508.557.
CUDC-907
CUDC-907 is a dual PI3K and HDAC inhibitor. Studies have shown CUDC-907 is able to enhance antitumor activity when combined with standard of care agents in multiple myeloma and B cell lymphoma xenograft models. Group: Biochemicals. Alternative Names: N-Hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-5-pyrimidinecarboxamide; N-Hydroxy-2-[[[2- (6-methoxypyridin-3-yl) -4- (morpholin-4-yl) thieno[3, 2-d]pyrimidin-6-yl]methyl] (methyl) amino]pyrimidine-5-carboxamide. Grades: Highly Purified. CAS No. 1339928-25-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CUDC-907-d3
CUDC-907-d3. Group: Biochemicals. Alternative Names: N-Hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-5-pyrimidinecarboxamide-d3; N-Hydroxy-2-[[[2- (6-methoxypyridin-3-yl) -4- (morpholin-4-yl) thieno[3, 2-d]pyrimidin-6-yl]methyl] (methyl) amino]pyrimidine-5-carboxamide-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H21D3N8O4S, Molecular Weight: 511.57. US Biological Life Sciences.
Worldwide
Cudetaxestat
Cudetaxestat (BLD-0409) is a potent and orally active autotaxin (ATX) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLD-0409. CAS No. 1782070-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145561.
Cudraflavone B is a prenylated flavonoid with anti-inflammatory and anti-tumor properties. Cudraflavone B is also a dual inhibitor of COX-1 and COX-2. Cudraflavone B blocks the translocation of nuclear factor κB (NF-κB) from the cytoplasm to the nucleus in macrophages. Thus, Cudraflavone B inhibits tumor necrosis factor α (TNFα) gene expression and secretion. Cudraflavone B also triggers the mitochondrial apoptotic pathway, activates NF-κB, the MAPK p38, and ERK, and induced the expression of SIRT1. Thus Cudraflavone B inhibits the growth of human oral squamous cell carcinoma cells. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 19275-49-1. Molecular formula: C25H24O6. Mole weight: 420.45. Purity: 0.98. IUPACName: 8-(2,4-dihydroxyphenyl)-5-hydroxy-2,2-dimethyl-7-(3-methylbut-2-enyl)pyrano[3,2-g]chromen-6-one. Canonical SMILES: CC(=CCC1=C(OC2=CC3=C(C=CC(O3)(C)C)C(=C2C1=O)O)C4=C(C=C(C=C4)O)O)C. Product ID: ACM19275491. Alfa Chemistry ISO 9001:2015 Certified.
Cuelure
Cuelure. Uses: Cleaning Products, Cosmetics, Flavor and Fragrances, Personal care. Group: Plant Extracts. INCI Names: 4-(3-Oxobutyl)phenyl acetate. Grades: FOOD GRADE. CAS No. 3572-6-3. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: PH-002. Olfactive Profile: Raspberry-like. EC No: 222-682-0. FEMA No: 3652. Origin: Indonesia.
New Jersey
Cue-lure
Cue-lure (Q-lure) is a melon fly attractant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Q-lure. CAS No. 3572-6-3. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-N7099.
Cuevaene A
It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. Synonyms: (2E,4Z,6E)-7-(8-hydroxy-1,2,3,4-tetrahydrodibenzo[b,d]furan-1-yl)-4-methoxy-6-methylhepta-2,4,6-trienoic acid. CAS No. 1246172-08-6. Molecular formula: C21H22O5. Mole weight: 354.40.
Cuevaene B
It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. CAS No. 274684-11-6. Molecular formula: C21H24O7. Mole weight: 388.41.
Cu+-exporting ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme transports Cu+ or Ag+, and cannot transport the divalent ions, contrary to EC 3.6.3.4, Cu2+-exporting ATPase, which mainly transports the divalent copper ion. Group: Enzymes. Synonyms: CopA; ATP7A; ATP7B. Enzyme Commission Number: EC 7.2.2.8 (Formerly EC 3.6.3.54). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4693; Cu+-exporting ATPase; EC 3.6.3.54; CopA; ATP7A; ATP7B. Cat No: EXWM-4693.
Cu Foam
Cu Foam. Group: Metal foams. ≥99.8%.
Cu Foil
Cu Foil. Group: Metal foils. CAS No. 7440-50-8. ≥99.8%.
Cu Foil Graphene
Cu Foil Graphene. Group: Metal foils. CAS No. 7440-50-8. 99.9%.
Cu Foil Graphene
Cu Foil Graphene. Group: Graphene nanopowders. CAS No. 7782-42-5. Mole weight: C on Cu foil. 99.9%.
CUG
CUG. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Carboxyumbelliferylbeta-D-galactopyranoside. Product Category: Other Fluorophores. CAS No. 64664-99-9. Molecular formula: C16H16O10. Mole weight: 368.29. Purity: 95%+. IUPACName: 2-oxo-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromene-3-carboxylicacid. Canonical SMILES: C1=CC2=C(C=C1O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O)OC(=O)C(=C2)C(=O)O. Density: 1.717 ± 0.06 g/ml. Product ID: ACM64664999-1. Alfa Chemistry ISO 9001:2015 Certified.
CUG
CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λ ex =386, λ em =445 nm, ε=32K). Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 3-Carboxyumbelliferyl-β-D-galactopyranoside. CAS No. 64664-99-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1026.