A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Css54 is an antibacterial peptide isolated from Centruroides suffusus. It has activity against Staphylococcus aureus (MIC=12.5 μg/ml) and Escherichia coli (MIC=12.5 μg/ml). Cytotoxicity. Synonyms: Phe-Phe-Gly-Ser-Leu-Leu-Ser-Leu-Gly-Ser-Lys-Leu-Leu-Pro-Ser-Val-Phe-Lys-Leu-Phe-Gln-Arg-Lys-Lys-Glu. Grades: 96.1%. Molecular formula: C138H221N33O33. Mole weight: 2870.47.
CST626
CST626 (Compound 9) is a pan- IAP degrader PROTAC. CST626 degrades XIAP, cIAP1 and cIAP2 with DC 50 s of 0.7, 2.4, and 6.2 nM in MM.1S cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033993-13-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149924.
CT1812
CT1812 (Sigma-2 receptor antagonist 1) is an orally active and brain penetrant sigma-2 receptor antagonist with a K i of 8.5 nM. CT1812 can be used for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sigma-2 receptor antagonist 1. CAS No. 1802632-22-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111669.
CT7001 hydrochloride
CT7001, also known as ICEC0942, is an orally bioavailable CDK7 inhibitor with IC50 value of 40nM. CDK7 phosphorylates the C-terminal domain (CTD) of RNA polymerase II (PolII) to enable transcription initiation, and also affects some transcriptional factor activities, resulting in suppression of types of cancers. Synonyms: ICEC0942 hydrochloride; (3R,4R)-4-[[[7-(benzylamino)-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol hydrochloride. CAS No. 1805789-54-1. Molecular formula: C22H31ClN6O. Mole weight: 430.97.
CTA056
CTA056 is a potent and selective ITK inhibitor (interleukin-2-inducible T-cell kinase inhibitor). ITK is a member of the Btk (Bruton's tyrosine kinase) family of tyrosine kinases, plays an important role in normal T-cell functions and in the pathophysiology of both autoimmune diseases and T-cell malignancies. CTA056 exhibits the highest inhibitory effects toward Itk, followed by Btk and endothelial and epithelial tyrosine kinase. Among the 41 cancer cell lines analyzed, CTA056 selectively targets acute lymphoblastic T-cell leukemia and cutaneous T-cell lymphoma. CTA056 may be potential therapeutic agent for the treatment of T-cell leukemia and lymphoma. Synonyms: CTA-056; CTA 056; 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one. Grades: 98%. CAS No. 1265822-30-7. Molecular formula: C35H34N6O. Mole weight: 554.69.
Ct-AMP1
HGAPDH is a plant defensin isolated from Clitoria ternatea. It has activity against gram-positive bacteria and fungi. Synonyms: Asn-Leu-Cys-Glu-Arg-Ala-Ser-Leu-Thr-Trp-Thr-Gly-Asn-Cys-Gly-Asn-Thr-Gly-His-Cys-Asp-Thr-Gln-Cys-Arg-Asn-Trp-Glu-Ser-Ala-Lys-His-Gly-Ala-Cys-His-Lys-Arg-Gly-Asn-Trp-Lys-Cys-Phe-Cys-Tyr-Phe-Asp-Cys. Molecular formula: C234H344N76O71S8. Mole weight: 5614.25.
CTAP
CTAP. Group: Biochemicals. Grades: Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTAP
CTAP has been found to be a selective μ-opioid receptor antagonist. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-arginyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide cyclic (2?7)-disulfide. Grades: ≥95% by HPLC. CAS No. 103429-32-9. Molecular formula: C51H69N13O11S2. Mole weight: 1104.32.
CTAP (Mu Opioid Receptor Antagonist, CTAP)
A highly potent octapeptide that acts as a selective and brain penetrating bioavailable u opioid receptor antagonist (IC50 = 3.5nM). Used in studies of reward systems and additions. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTAP TFA
CTAP TFA is a potent brain penetrant μ opioid receptor antagonist (IC50 = 3.5 nM) and displays over 1200-fold selectivity over δ opioid (IC50 = 4500 nM) and somatostatin receptors. Synonyms: Cys2, Tyr3, Arg5, Pen7-Amide TFA. Grades: 99%. Molecular formula: C53H70F3N13O13S2. Mole weight: 1218.32.
CTAP trifluoroacetate salt
CTAP is a water-soluble and selective antagonist of the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM). It is a cyclic octapeptide which acts as a poor antagonist of the somatostatin receptor (IC50 = 14.3 μM). CTAP is at least 10-fold more potent than naltrexone. Molecular formula: C51H69N13O11S2·xCF3COOH. Mole weight: 1104.31.
CTB
CTB is a potent p300 histone acetyltransferase activator [1]. CTB can effectively induce apoptosis in MCF-7 cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 451491-47-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134964.
CTB ACT activator
Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of Histone. This small molecule/inhibitor is primarily used for Cell Structure applications. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTB ACT activator; CTB; Histone Acetyltransferase Activator. Product Category: Activators. Appearance: Solid powder. CAS No. 451491-47-7. Molecular formula: C16H13ClF3NO2. Mole weight: 343.73. Purity: >98%. IUPACName: N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide. Canonical SMILES: O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=CC=CC=C2OCC. Product ID: ACM451491477-1. Alfa Chemistry ISO 9001:2015 Certified.
CTCE 9908
It is a CXCR4 antagonist that induces mitotic catastrophe in ovarian cancer cells. Synonyms: L-Lysinamide, N2,N6-bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-; CTCE-9908; CTCE9908; H-Lys-Gly-Val-Ser-Leu-Ser-Tyr-Arg-Lys(1)-NH2.H-Lys-Gly-Val-Ser-Leu-Ser-Tyr-Arg-(1). Grades: >98%. CAS No. 1030384-98-5. Molecular formula: C86H147N27O23. Mole weight: 1927.27.
CTCE 9908
CTCE 9908. Group: Biochemicals. Grades: Purified. CAS No. 1030384-98-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTCE-9908
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1030384-98-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1103.
C-telopeptide
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen and an RIA based on monoclonal antibody raised against this 8-amino-acid sequence was developed. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Synonyms: H-Glu-Lys-Ala-His-Asp-Gly-Gly-Arg-OH; L-alpha-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-alpha-aspartyl-glycyl-glycyl-L-arginine; (2S,11S,14S,17S,20S,23S)-14-((1H-imidazol-4-yl)methyl)-23-amino-20-(4-aminobutyl)-11-(carboxymethyl)-2-(3-guanidinopropyl)-17-methyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazahexacosane-1,26-dioic acid; CTX. Grades: ≥95%. CAS No. 162929-64-8. Molecular formula: C34H56N14O13. Mole weight: 868.89.
C-telopeptide acetate
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Synonyms: CTX acetate. Molecular formula: C36H60N14O15. Mole weight: 928.95.
CTEP
CTEP (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC 50 of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors. CTEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 4956371; mGluR5 inhibitor. CAS No. 871362-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15445.
CTEP
CTEP is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor (IC50=2.2 nM), showing >1000-fold selectivity over other mGlu receptors. Synonyms: RO4956371; RO-4956371; RO 4956371; CTEP. Grades: >98%. CAS No. 871362-31-1. Molecular formula: C19H13ClF3N3O. Mole weight: 391.77.
C-terminal processing peptidase
Proteolytic processing of the D1 protein of photosystem II is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation. The recognition of the substrate is mediated by a PDZ domain, a small protein module that promotes protein-protein interactions by binding to internal or C-terminal sequences of their partner proteins. Type example of peptidase family S41. Group: Enzymes. Synonyms: CtpA gene product (Synechocystis sp.); photosystem II D1 protein processing peptidase; protease Re; tail-specific protease; Tsp protease. Enzyme Commission Number: EC 3.4.21.102. CAS No. 216484-75-2, 92480-11-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4097; C-terminal processing peptidase; EC 3.4.21.102; 216484-75-2, 92480-11-0; CtpA gene product (Synechocystis sp.); photosystem II D1 protein processing peptidase; protease Re; tail-specific protease; Tsp protease. Cat No: EXWM-4097.
CTLA-4 inhibitor
CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Synonyms: MDK24720; MDK 24720; MDK-24720; CTLA-4 inhibitor. 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one; EX-A913. CAS No. 635324-72-0. Molecular formula: C21H13F4N5O. Mole weight: 427.363.
cTMP
cTMP (2?,3?-dideoxy-3?-thiothymidine) is an exceptional biomedical compound ubiquitously applied in studying the pernicious Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS). Functioning as a high-potency antiretroviral compound, cTMP exercises its efficacious mechanism by adeptly obstructing the pernicious reverse transcriptase enzyme. Synonyms: Thymidine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 76567-90-3. Molecular formula: C10H12N2O7P · Na. Mole weight: 326.2.
CTOP
CTOP has been found to be an effective and selective μ opioid receptor antagonist and could be used in the treatment of pain. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide Cyclic (2?7)?-Disulfide. Grades: 98%. CAS No. 103429-31-8. Molecular formula: C50H67N11O11S2. Mole weight: 1062.28.
CTOP
CTOP. Group: Biochemicals. Grades: Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTOP (Mu Opioid Receptor Antagonist, CTOP)
A potent antagonist highly selective for Mu opioid receptor (Ki = 0.96nM for u receptor and > 10,000nM for delta receptors). Often used for studying the functional roles of Mu opioid receptors in both central and peripheral nervous systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTOP trifluoroacetate salt
CTOP is a peptide that acts as a selective antagonist of the μ-opioid receptor (IC50 = 2.8 nM). CTOP inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED50 = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED50 = 0.02 nmol). Synonyms: Phe-Cys-Tyr-Trp-Orn-Thr-Pen-Thr; D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide-cyclic (2?7)-disulfide trifluoroacetate salt. Grades: ≥98%. Molecular formula: C50H67N11O11S2·xCF3COOH. Mole weight: 1062.3 (free base).
CTP
CTP is a cardiac targeting peptide. CTP transduces cardiomyocytes in vitro. CTP leads to efficient and specific transduction of heart tissue in mice model. CTP can be used to deliver therapeutic peptides, proteins and nucleic acid specifically to the heart [1]. Uses: Scientific research. Group: Peptides. CAS No. 1052692-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4094.
CTPαS
CTPαS, a molecule activator of soluble guanylate cyclase (sGC), is vying for a preeminent position in the study of nitric oxide signaling pathway. With its therapeutic potential locked and loaded, CTPαS is turning heads in the scientific community, demonstrating potential efficacy in addressing cardiovascular diseases such as hypertension and pulmonary arterial hypertension, as well as a wide range of central nervous system conditions, including neurodegenerative diseases and pain management alike. Synonyms: Cytidine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grades: ≥ 95% by HPLC. Molecular formula: C9H16N3O13P3S (free acid). Mole weight: 499.21 (free acid).
Ctpb
Ctpb. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-CHLORO-3-TRIFLUOROMETHYL-PHENYL)-2-ETHOXY-6-PENTADECYL-BENZAMIDE;CTPB. Product Category: Heterocyclic Organic Compound. Appearance: White to off-white crystalline solid. CAS No. 586976-24-1. Molecular formula: C31H43ClF3NO2. Mole weight: 554.1268296. Product ID: ACM586976241. Alfa Chemistry ISO 9001:2015 Certified. Categories: CTP Ia?i.
CTPB
CTPB is a good activator of p300 histone acetyl transferase ( HAT ) enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 586976-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124960.
CTPB
CTPB is an amide derivative that acts as a selectively activator of the histone acetyltransferase (HAT) p300, with maximal activation at 275 μM. Synonyms: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide. Grades: ≥98%. CAS No. 586976-24-1. Molecular formula: C31H43ClF3NO2. Mole weight: 554.1.
CTP-dependent riboflavin kinase
This archaeal enzyme differs from EC 2.7.1.26, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP. Group: Enzymes. Synonyms: Methanocaldococcus jannaschii Mj0056; Mj0056. Enzyme Commission Number: EC 2.7.1.161. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2991; CTP-dependent riboflavin kinase; EC 2.7.1.161; Methanocaldococcus jannaschii Mj0056; Mj0056. Cat No: EXWM-2991.
CTP-γ-AmNS
CTP-γ-AmNS is a fluorescent analogue of CTP that is used for the determination of enzymes specialized to cleave α/β-phosphodiester bonds. Synonyms: Cytidine- 5'- O- triphosphoro- γ- 1- (5- sulfonic acid)naphthylamidate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 84230-52-4. Molecular formula: C19H23N4O16P3S (free acid). Mole weight: 688.4 (free acid).
CTPI-2
CTPI-2 is the third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. Synonyms: SLC25A1 Inhibitor CTPI-2; Benzoic Acid, 2-[[(4-Chloro-3-Nitrophenyl)Sulfonyl]Amino]-; 2-[(4-Chloro-3-Nitrophenyl)Sulphonyl]Anthranilic Acid. Grades: 98%. CAS No. 68003-38-3. Molecular formula: C13H9ClN2O6S. Mole weight: 356.74.
CTP - lyophilized
The lyophilized form of CTP. CTP is a P2X purinergic receptor agonist that can be used in the synthesis of RNA. In metabolic reactions, it acts as a coenzyme. Synonyms: Cytidine 5'-triphosphate, Disodium salt trihydrate. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N3Na2O14P3* 3H2O. Mole weight: 581.16.
CTP - solution
CTP Synthase (Crude Enzyme)
This product with the indicated enzyme activity was briefly purified from engineered E.coli. Applications: Analysis; drug development; medicine. Group: Enzymes. Synonyms: UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Enzyme Commission Number: EC 6.3.4.2. CAS No. 9023-56-7. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Pack: 100ml. Cat No: NATE-1862.
CTP synthase (glutamine hydrolysing)
The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2, glutaminase), and the active site where CTP synthesis takes place. The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP. Ammonia then reacts with this intermediate generating CTP and a phosphate. The enzyme can also use ammonia from the surrounding solution. Group: Enzymes. Synonyms: UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Enzyme Commission Number: EC 6.3.4.2. CAS No. 9023-56-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5789; CTP synthase (glutamine hydrolysing); EC 6.3.4.2; 9023-56-7; UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Cat No: EXWM-5789.
CTS-1027
CTS-1027 inhibits individual members of the MMP family that are believed to be important in inflammation and tissue damage. CTS-1027 was specifically designed, however, not to inhibit MMP 1, as inhibition of MMP 1 was believed to be associated with musculoskeletal side effects. Synonyms: RS 130830; Ro 1130830; CTS1027; CTS 1027; RS130830; Ro1130830; RS-130830; Ro-1130830. Grades: >98%. CAS No. 193022-04-7. Molecular formula: C19H20ClNO6S. Mole weight: 425.88.
CTS-21166
CTS-21166, the selective BACE1 inhibitor whose structure is not revealed, reduce brain Aβ levels by over 35% and plaque load by 40%. Phase 1 IC50=1.2-3.6 nM (cell line details NA) APP transgenic mice, 4mg/kg i.p. injection for 6 weeks, >35% ↓ brain Aβ, 40% ↓ plaque load. Human patients, 7.5.225 mg i.v. injection dose-dependant ↓ plasma Aβ, 80% ↓ at 225 mg. Synonyms: ATG-Z1; CTS-21166; ZPQ-21166; ATG Z1; CTS 21166; ZPQ 21166; ATGZ1; CTS21166; ZPQ21166. Molecular formula: none.
CT Series Talc
CT Industrial Talcs can be used in a wide range of industrial and specialty applications. CT Industrial Talcs are produced from an extensive depositof high quality platy talc ore. CT series talcs are a cost effective formulating tool for moderate brightness applications. Pack Sizes Available: 50 lbs bags, 2,000 lbs pallets.
AG&P Mineral Purveyors
CTTHWGFTLC, CYCLIC acetate
CTTHWGFTLC, CYCLIC acetate is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: L-Cysteine, L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophylglycyl-L-phenylalanyl-L-threonyl-L-leucyl-, cyclic (1?10)-disulfide acetate; CTT 1 acetate; H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH.CH3CO2H (Disulfide Bridge: Cys1-Cys10); L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide acetic acid acetate. Grades: ≥95%. Molecular formula: C54H75N13O16S2. Mole weight: 1226.39.
CTX-0294885
CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTx-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx-0294885-bound beads for kinase enrichment. Large-scale CTx-0294885-based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTx-0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies. Synonyms: CTX-0294885; CTX 0294885; CTX0294885; CTx 0294885. Grades: 98%. CAS No. 1439934-41-4. Molecular formula: C22H24ClN7O. Mole weight: 437.93.
CTX-0294885 hydrochloride
CTX-0294885 hydrochloride is the hydrochloride salt of CTX-0294885 which displays high affinity toward an extensive range of kinases. The evaluation of the binding profile of CTx-0294885 in MDA-MB-231 cells by quantitative MS demonstrated its selective properties as a kinase enrichment reagent. Synonyms: 2-[[5-chloro-2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide;hydrochloride; CTX-0294885 hydrochloride; CTX 0294885 hydrochloride; CTX0294885 hydrochloride. Molecular formula: C22H25Cl2N7O. Mole weight: 474.39.
CTX1
CTX1 is a p53 activator that overcomes HdmX-mediated p53 repression. CTX1 exhibits potent anti-cancer activity in a mouse acute myeloid leukemia (AML) model system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 501935-96-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-U00442.
CTX-471
CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with K d values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2377152-49-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99178.
CTX-712
CTX-712 is an orally effective CLK 2 inhibitor, with an IC 50 of 1.4 nM, showing anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2144751-78-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144875.
C-Type Natriuretic Peptide (1-53), human
C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide, which belong to the natriuretic peptide family and is involved in the maintenance of electrolyte-fluid balance and vascular tone. Synonyms: CNP-53 (human); Asp-Leu-Arg-Val-Asp-Thr-Lys-Ser-Arg-Ala-Ala-Trp-Ala-Arg-Leu-Leu-Gln-Glu-His-Pro-Asn-Ala-Arg-Lys-Tyr-Lys-Gly-Ala-Asn-Lys-Lys-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys (Disulfide bond). Grades: ≥95%. CAS No. 141294-77-1. Molecular formula: C251H417N81O71S3. Mole weight: 5801.77.
C-Type Natriuretic Peptide-22 (human, porcine, rat) trifluoroacetate salt
C-Type natriuretic peptide-22 is an endogenous peptide which has diverse biological activities. CNP-22 acts as a selective agonist of natriuretic peptide receptors (NPRs) 2 and 3 (Kds = 7, 10.8, and >500,000 pM for NPR2, 3, and 1, respectively). The 22 amino acid sequence corresponds to residues 105-126 of its precursors prepro CNP, pro CNP, and CNP-53. Synonyms: CNP-22; glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (6?22)-disulfide trifluoroacetate salt. Grades: ≥95%. Molecular formula: C93H157N27O28S3·xCF3COOH. Mole weight: 2197.60.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-type natriuretic peptide is an endogenous peptide found in plasma and cerebrospinal fluid. It is composed of 22 amino acids. C-type natriuretic peptide acts as an agonist of natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). It inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo. Synonyms: H-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH; glycyl-L-leucyl-L-seryl-L-lysyl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-seryl-L-methionyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteine (6->22)-disulfide; Natriuretic peptide, C-type; C-type natriuretic peptide (1-22) (human, rat, swine); Atriopeptin C (pig); C-Type Natriuretic Peptide (32-53) (human, porcine, rat). Grades: ≥95%. CAS No. 127869-51-6. Molecular formula: C93H157N27O28S3. Mole weight: 2197.60.
Cu. Group: Elements nanoparticles. 99.8% (metal basis).
Cu2+-exporting ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell. Group: Enzymes. Synonyms: CopB. Enzyme Commission Number: EC 3.6.3.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4678; Cu2+-exporting ATPase; EC 3.6.3.4; CopB. Cat No: EXWM-4678.
CU-32
CU-32 is a potent cGAS inhibitor with an IC 50 of 0.45 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2400954-16-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132221.
CuAlMnTi High-Entropy Alloy Ingots
We are engaged in the development, production, and sales of CuAlMnTi High-Entropy Alloy Ingots and provide personalized customization service for high-quality metal powder. CuAlMnTi High-Entropy Alloy is a new alloy with very unique properties. Uses: Used in manufacturing super alloys and electron-beam melting. used in metallurgical, machinery processing, glass, and ceramic industries. used in electronics industry, such as integrated circuits. used in the field of glass coating. Group: High entropy alloys. Pack Sizes: Our CuAlMnTi High-Entropy Alloy Ingot is carefully handled during storage and transportation to preserve the quality of our product in its original condition. 0.99.
CuAlMnTi High-Entropy Alloy Spherical Powder
We are engaged in the development, production and sales of CuAlMnTi high entropy alloy spherical powder, and provide personalized service of high quality metal powder. CuAlMnTi high entropy alloy spherical powder is a new type of alloy with very unique properties. Uses: Cualmnti high-entropy alloy spherical powder is widely used in aerospace parts and auto parts, profile surface spraying, powder metallurgy, nuclear energy and industrial fields. Group: High entropy alloys.
CuAlTiWV High-Entropy Alloy Spherical Powder
CuAlTiWV High-Entropy Alloy Spherical Powder is composed of Cu, Al, Ti, W, V. Alfa Chemistry offers high-quality High-Entropy Alloy with competitive pricing. Uses: Cualtiwv high-entropy alloy spherical powder is widely used in aerospace parts and auto parts, profile surface coating, powder metallurgy, nuclear energy and industrial fields. Group: High entropy alloys. Pack Sizes: Our CuAlTiWV High-Entropy Alloy Spherical Powder is carefully handled during storage and transportation to preserve the quality of our product in its original condition.
CuATSM
CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68341-09-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139827.
Cuban Tobacco Fragrance Oil
Cuban Tobacco Fragrance Oil.
CA, FL & NJ
cubebol synthase
Requires Mg2+. The enzyme gives 28% cubebol, 29% (-)-germacrene D, 10% (+)-Δ-cadinene and traces of several other sesquiterpenoids. See also EC 4.2.3.75 (-)-germacrene D synthase and EC 4.2.3.13 (+)-Δ-cadinene synthase. Group: Enzymes. Synonyms: Cop4. Enzyme Commission Number: EC 4.2.3.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5255; cubebol synthase; EC 4.2.3.91; Cop4. Cat No: EXWM-5255.
Cubeb Pepper Oil
Cubeb essential oilsis a warm, sweet oil with a slight peppery characteristic. Although Cubeb (Piper cubeba) has similarities to Black Pepper (Piper nigrum), Cubeb essential oilsis not as peppery in aroma as Black Pepper Essential Oil. It's a softer, mellower, warming essential oilsthat serves as a middle-base note in fragrancing applications. Cubeb oil is derived from the fruits of the cubebs plants. Cubeb plants are native to Java and Sumatra Islands but are also grown in India, Sri Lanka, and Reunion, too. Uses: Essential Oils, Pharmaceutical. Group: Plant Extracts. INCI Names: Piper Cubeba (Cubeb Pepper) Fruit Oil. Grades: FOOD GRADE. CAS No. 90082-59-0. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CB-002. Olfactive Profile: Spicy, pepper-like, piperine, mint-like. EC No: 290-148-4. FEMA No: 2339. Origin: Indonesia.
New Jersey
Cubeb Pepper Oil - CO2
Cubeb essential oilsis a warm, sweet oil with a slight peppery characteristic. Although Cubeb (Piper cubeba) has similarities to Black Pepper (Piper nigrum), Cubeb essential oilsis not as peppery in aroma as Black Pepper Essential Oil. It's a softer, mellower, warming essential oilsthat serves as a middle-base note in fragrancing applications. Cubeb oil is derived from the fruits of the cubebs plants. Cubeb plants are native to Java and Sumatra Islands but are also grown in India, Sri Lanka, and Reunion, too. Uses: Pharmaceutical. Group: Plant Extracts. INCI Names: Piper Cubeba (Cubeb Pepper) Fruit Oil. Grades: FOOD GRADE. CAS No. 90082-59-0 ; 8007-87-2. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CB-001. Olfactive Profile: Spicy, pepper-like, piperine, mint-like. EC No: 290-148-4. FEMA No: 2339. Origin: Indonesia.
New Jersey
Cubenol
Cubenol was used for biological study of antioxidant and antimicrobial activity and comparison of cinnamon leaf and bark essential oils and oleoresins. Cubenol was one of the major components of essential oils isolated from the aerial parts of Artemisia absinthium, Artemisia santonicum and Artemisia spicigera. Group: Biochemicals. Grades: Highly Purified. CAS No. 21284-22-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C15H26O, Molecular Weight: 222.37. US Biological Life Sciences.
CU CPT 22 is a selective TLR1/2 inhibitor (IC50 = 0.58 μM). Synonyms: CU-CPT22; CU-CPT 22; CU-CPT-22; CUCPT22; CUCPT 22; CUCPT-22; 3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester. CAS No. 1416324-85-0. Molecular formula: C19H22O7. Mole weight: 362.37.
CU CPT 4a
CU CPT 4a is a selective TLR3 inhibitor (IC50 = 3.44 μM in RAW 264.7 cells). Synonyms: CU CPT 4a; CU-CPT-4a; CUCPT4a; N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine. CAS No. 1279713-77-7. Molecular formula: C18H13ClFNO3S. Mole weight: 377.82.
CU-CPT 4a
CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TLR3-IN-1. CAS No. 1279713-77-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108473.
CU-CPT-8m
CU-CPT-9m is a TLR8 antagonist with an IC50 of 67 nM. Synonyms: CU-CPT-8m, CU-CPT 8m, CU-CPT8m; 7-(m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide; 7-(3-methylphenyl) pyrazolo(1,5-a)pyrimidine-3-carboxamide; 7-(3-methylphenyl) pyrazolo[1,5-a]pyrimidine-3-carboxamide; CU-CPT8m. CAS No. 125079-83-6. Molecular formula: C14H12N4O. Mole weight: 252.277.
CU-CPT-9a
CU-CPT-9a is a TLR8 antagonist with an IC50 of 0.5 nM. Synonyms: CU-CPT9b; CUCPT9b; CU CPT9b; HY-112667; CS-0059157; HY 112667; CS 0059157; HY112667; CS0059157; 4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol; 2-Methyl-4-(7-hydroxyl-4-quinolinyl)-phenol. CAS No. 2162962-69-6. Molecular formula: C16H13NO2. Mole weight: 251.285.