A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
D-Buthionine. Group: Biochemicals. Alternative Names: S-Butyl-D-homocysteine; D-2-Amino-4-(butylthio)butyric acid; n-Butyl-D-homocysteine. Grades: Highly Purified. CAS No. 13073-22-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H17NO2S. US Biological Life Sciences.
Worldwide
D-Buthionine-(S,R)-sulfoximine
D-Buthionine-(S,R)-sulfoximine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-4- (S-butylsulfonimidoyl) butanoic acid; D-Buthionine sulfoximine. Grades: Highly Purified. CAS No. 113158-69-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H18N2O3S. US Biological Life Sciences.
Worldwide
DBZ
DBZ. Group: Biochemicals. Grades: Purified. CAS No. 209984-56-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DBZ
DBZ, also called dibenzazepine, is a γ-secretase inhibitor to treat Alzheimer's Disease, and it also inhibits Notch signaling. Synonyms: YO-01027; YO 01027; YO01027; (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide; dibenzazepine; GSI XX; Dibenzazepine; 209984-56-5; YO-01027; (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide; Deshydroxy LY 411575; gamma-Secretase Inhibitor XX; DBZ; 209984-56-5 pound not YO 01027; (S,S)-2-[2-(3,5-Difluorophenyl)acetylamino]-N-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propionamide; N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide; C26H23F2N3O3; GSI-XX; g-secretase inhibitor XX; Gamma-secretase inhibitor; Deshydroxy LY-411514; Deshydroxy LY-411575; MLS006011073; SCHEMBL3046688; DTXSID6040458; AOB1375; ANW-62574; ZINC22056928; AKOS016004347; RL02593; YO01027; NCGC00263188-01; AC-27417; AJ-80844; AK101890; BC638679; SMR004676467; AB0033830; KB-210919; TC-151319; FT-0666470; ST24035862; X7602; Z-3141; (2S)-2-[2-(3,5-. Grades: >98%. CAS No. 209984-56-5. Molecular formula: C26H23F2N3O3. Mole weight: 463.48.
DBzA
DBzA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Methyl-2-(4-(9-(4-(6-methylbenzo[d ]thiazol-2-yl)phenyl)anthracen-10-yl)phenyl)benzo[d ]thiazole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 850018-19-8. Molecular formula: C42H28N2S2. Mole weight: 624.82 g/mol. Product ID: ACM850018198. Alfa Chemistry ISO 9001:2015 Certified.
DBZ (N-[(1S)-2-[[(7S)-6,7-Dihydro-5-meth yl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl -2-oxoethyl] -3, 5-difluoro Benzene acetamide) . Group: Biochemicals. Grades: Highly Purified. CAS No. 209984-56-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
DC-009
DC-009 is a small-molecule thrombolytic that can scavenge the free radical in cells. Studies in vitro and in vivo showed that DC-009 had the similar activity as recombinant tissue plasminogen activator (rt-PA) and dose-dependent activity. Further study of treating ischemic stroke is planned. Uses: The potential treatment of ischemic stroke. Synonyms: DC009; DC 009.
DC-05 is a potent and selective non-nucleoside DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 10.3 uM. It has significant selectivity toward other AdoMet-dependent protein methyltransferases. It significantly inhibits cancer cell proliferation. It inhibitis DNMT1 by binding to DNMT1 instead of incorporating into DNA. Uses: Dc-05 inhibits cancer cell proliferation. Synonyms: DC-05; DC 05; DC05; 1-Carbazol-9-yl-3-[2-(1H-indol-3-yl)ethylamino]propan-2-ol. Grades: >98 %. CAS No. 890643-16-0. Molecular formula: C25H25N3O. Mole weight: 383.49.
DC-05
DC-05 is a DNA methyltransferase 1 ( DNMT1 ) inhibitor, with an IC 50 and a K d of 10.3 μM and 1.09 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 890643-16-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12746.
DC-102
DC-102 is produced by the strain of Streptomyces sp. It has anti-gram-positive bacteria activity and anti-tumor effect. Synonyms: DC 102 Antibiotic; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-7-((4,6-dideoxy-3-C-methyl-4-(methylamino)-alpha-L-mannopyranosyl)oxy)-11-methoxy-2-propylidene-. CAS No. 115722-50-4. Molecular formula: C24H35N3O6. Mole weight: 461.55.
DC-120
DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT signal pathway in dose- and time-dependent manners both in vitro and in vivo. DC120 inhibits AKT activity in vitro with an EC(50) of 153 nM. DC120 at 20 mg/kg/day inhibited the CNE2 xenograft tumor growth with a treated group/control group ratio of 38.1%, accompanied by increasing terminal deoxynucleotidyl transferasedUTP nick-end labeling-positive cells in the tumor sample. Synonyms: DC-120; DC 120; DC120. Grades: 98%. CAS No. 1261080-40-3. Molecular formula: C18H18Cl2N6OS. Mole weight: 437.35.
DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca 2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC 50 : 6.28, 5.96, 7.07, 4.58 μM, respectively) [1]. DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 346692-04-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101906.
DC 260126
DC 260126. Group: Biochemicals. Grades: Purified. CAS No. 346692-04-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DC 260126
DC 260126 is a free fatty acid receptor 1 (FFA1/GPR40) antagonist that decreases intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro. It was shown to lower serum insulin levels, improve insulin sensitivity and reduces the rate of apoptotic pancreatic β cells in obese diabetic (db/db) rats. Synonyms: DC 260126; DC260126; DC-260126; N-(4-Butylphenyl)-4-fluorobenzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 346692-04-4. Molecular formula: C16H18FNO2S. Mole weight: 307.38.
DC271
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 198696-03-6. Pack Sizes: 1 mg. Product ID: HY-D1190.
DC41
DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. Synonyms: DC41; 1354787-69-1; AKOS040732937; HY-112901; CS-0067648; N-{2-[(1S)-1-(chloromethyl)-5-hydroxy-1H,2H,3H-benzo[e]indole-3-carbonyl]-1H-indol-5-yl}-5-(4-methyl-4-sulfanylpentanamido)-1H-indole-2-carboxamide. CAS No. 1354787-69-1. Molecular formula: C37H34ClN5O4S. Mole weight: 680.21.
DC41-SMe
DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. CAS No. 1354787-71-5. Molecular formula: C38H36ClN5O4S2. Mole weight: 726.31.
DC4 Crosslinker
DC4 Crosslinker is a stable crosslinking reagent with improved activity and solubility. DC4 Crosslinker is labile cleavable with collision-induced dissociation (CID), that will be fragmented into four rearrange products containing mobilized protons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374647-94-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120937.
DC_517
DC_517 is a novel selective non-nucleoside inhibitor of DNMT1. (IC50 = 1.7 μM), was found to be more potent than DC_05. Uses: A novel selective non-nucleoside inhibitor. Synonyms: DC-517; DC 517; DC517; 1-{[1,3-Di(9H-carbazol-9-yl)-2-propanyl]oxy}-3-(isopropylamino)-2-propanol. Grades: ≥98%. CAS No. 500017-70-9. Molecular formula: C33H35N3O2. Mole weight: 505.65.
DC661
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1872387-43-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111621.
DC661
DC661 is an effective palmitoyl-protein thioesterase 1 (PPT1) inhibitor that inhibits autophagy and ACTS as an antilysosomal agent. Compared with hydroxychloroquine (HCQ), DC661 has significant acid hydrolysis and autophagy inhibition. Synonyms: DC661; 1872387-43-3; N-(7-chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine; N1-(7-chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine; dc-661; C31H39Cl2N5; CHEMBL4873725; SCHEMBL19399303; BCP30743; EX-A2963; XZC38743; s8808; ZB1540; AKOS037649041; DC-661; DC 661; AC-35596; BS-16368; HY-111621; CS-0088759; D80814; 7-chloro-N-[6- ({6-[ (7-chloroquinolin-4-yl)amino]hexyl} (methyl)amino)hexyl]quinolin-4-amine. CAS No. 1872387-43-3. Molecular formula: C31H39Cl2N5. Mole weight: 552.58.
DC 81
DC 81 is originally isolated from Streptomyces roseiscleroticus DO-81. It has weak anti-gram-positive, anti-gram-negative and tumor activity. Synonyms: Antibiotic DC 81; (+)-1,2,3,11a-Tetrahydro-8-hydroxy-7-methoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one; 7-Methoxy-8-hydroxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 8-hydroxy-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one. CAS No. 81307-24-6. Molecular formula: C13H14N2O3. Mole weight: 246.26.
DC 838
DC 838 is a potent human cyclophilin A (CypA) inhibitor. Synonyms: DC 838; DC838; DC-838; 1-N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-N,3-N-diethylpiperidine-1,3-dicarboxamide. Grades: 99%. CAS No. 508186-08-1. Molecular formula: C27H29N5O4. Mole weight: 487.55.
DC 86M
It is originally isolated from Streptomyces lugeogriseus 86. DC 86M has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity, and can inhibit mouse sarcoma 180 cells. Synonyms: 6-(1-((Hydroxyacetyl)oxy)ethyl)-1-phenazinecarboxylic acid; DC-86-M; DC-86M; DC 86 M; 6-{1-[(Hydroxyacetyl)oxy]ethyl}phenazine-1-carboxylic acid. Grades: >98%. CAS No. 94448-15-4. Molecular formula: C17H14N2O5. Mole weight: 326.30.
DC92-B
It is originally isolated from Actinomadura sp. DC92-B is mainly resistant to Gram-positive bacteria, and it also has anti-tumor activity. Synonyms: DC 92B; 4H-Anthra(1,2-b)pyran-4,7,12-trione, 11-hydroxy-5-methyl-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D-arabino-hexopyranosyl)-10-(2,3,6-trideoxy-3-(dimethylamino)-5-C-hydroxy-3-C-methylhexopyranosyl)-2-(3,3',3'-trimethyl(2,2'-bioxiran)-3-yl)-. Grades: >98%. CAS No. 116988-30-8. Molecular formula: C42H52N2O12. Mole weight: 776.87.
DC92-D
It is originally isolated from Actinomadura sp. and DC92-D is mainly resistant to Gram-positive bacteria. Synonyms: DC 92D; 8-(4-(dimethylamino)-3-hydroxy-2-methyl-3,4-dihydro-2H-pyran-6-yl)-10-(3-(dimethylamino)-4,6-dihydroxy-3,6-dimethyltetrahydro-2H-pyran-2-yl)-11-hydroxy-5-methyl-2-(3,3',3'-trimethyl-[2,2'-bioxiran]-3-yl)-4H-naphtho[2,3-h]chromene-4,7,12-trione. CAS No. 116988-29-5. Molecular formula: C42H50N2O12. Mole weight: 774.85.
DCA
DCA is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. DCA also induces apoptosis and reverses the KV1.5 channels downregulation in cancer. Synonyms: Sodium dichloroacetate; Sodium 2,2-dichloroacetate; Dichloroacetic acid sodium salt. CAS No. 2156-56-1. Molecular formula: C2HCl2NaO2. Mole weight: 150.92.
DCAF is an electron-deficient azaacene and acts as an electron injection material for organic light-emitting diodes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40114-84-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-32247.
D-Campholic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-CAMPHOLIC ACID;1,2,2,3-Tetramethylcyclopentanecarboxylic acid;D-trans-1,2,2,3-Tetramethylcyclopentanecarboxylic acid;(1R,3R)-1,2,2,3-Tetramethylcyclopentanecarboxylic acid;[1R,(+)]-1,2,2,3α-Tetramethylcyclopentane-1β-carboxylic acid. Product Category: Heterocyclic Organic Compound. CAS No. 31147-56-5. Molecular formula: C10H18O2. Mole weight: 170.25. Product ID: ACM31147565. Alfa Chemistry ISO 9001:2015 Certified.
100g Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks. Formula: C10H16O. CAS No. 464-49-3. Prepack ID 54189554-100g. Molecular Weight 152.23. See USA prepack pricing.
D-(+)-Camphor
D-camphor appears as colorless or white crystals. Sublimes. Flash point 149°F. Burns readily with a bright, smoky flame. Penetrating aromatic odor. Pungent, aromatic taste followed by a sensation of cold. (NTP, 1992);White to gray translucent crystals or fused mass; Warm, minty, almost ethereal diffusive aroma;White to pale yellow crystalline solid, Camphoraceous aroma. Group: Plasticizers. CAS No. 464-49-3. Product ID: (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one. Molecular formula: 152.23g/mol. Mole weight: C10H16O. CC1(C2CCC1(C(=O)C2)C)C. InChI=1S/C10H16O/c1-9(2)7-4-5-10(9, 3)8(11)6-7/h7H, 4-6H2, 1-3H3/t7-, 10+/m1/s1. DSSYKIVIOFKYAU-XCBNKYQSSA-N.
D(+)-Camphor
Cas No. 464-49-3.
D-CAMPHOR
D-CAMPHOR. CAS No. 464-49-3. Product ID: CDC10-0574. Molecular formula: C10H16O. Category: Lip protectants. Product Keywords: Cosmetic Ingredients; Active Ingredients; Lip protectants; D-CAMPHOR; CDC10-0574; 464-49-3; C10H16O; 207-355-2; 464-49-3. Purity: 0.99. Color: White. EC Number: 207-355-2. Physical State: Crystals. Solubility: Slightly soluble in water, very soluble in alcohol and in light petroleum, freely soluble in fatty oils, very slightly soluble in glycerol. Storage: 2-8°C. Boiling Point: 204 °C. Melting Point: 178-182 °C (lit.).
D-Camphor sulfonic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
DCAP
DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500015-20-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136068.
D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 541-14-0. Pack Sizes: 250 mg; 1 g. Product ID: HY-W012550.
D-Carnitine
D-Carnitine is used as a building block for antidiabetic, microbicidal compounds. Group: Coenzymes. CAS No. 541-14-0. Purity: >96%. Mole weight: 161.2. Form: Solid. D-Carnitine; 541-14-0. Cat No: COEC-102.
D-Carnitine
Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado. Group: Biochemicals. Alternative Names: (2S)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Inner Salt; D- (3-Carboxy-2-hydroxypropyl) trimethyl Ammonium Hydroxide Inner Salt; (+)-Carnitine; (+)-D-Carnitine; D-(+)-Carnitine; d-Carnitine. Grades: Highly Purified. CAS No. 541-14-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
D-Carnitine hydrochloride 99+%
D-Carnitine hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 10017-44-4. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
d(+)-Carvone
d(+)-Carvone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Carvol. Product Category: Heterocyclic Organic Compound. Appearance: Clear colorless to pale yellow liquid. CAS No. 2244-16-8. Molecular formula: C10H14O. Mole weight: 150.22. Purity: 0.98. IUPACName: (5S)-2-Methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one. Canonical SMILES: CC1=CCC(CC1=O)C(=C)C. Density: 0.96 g/mL at 25 °C(lit.). Product ID: ACM2244168. Alfa Chemistry ISO 9001:2015 Certified.
D-(+)-Carvone
D-(+)-Carvone, is used for the synthesis of (-)-terpestacin, a fungal metabolite with anticancer activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 2244-16-8. Pack Sizes: 10g, 25 g. Molecular Formula: C10H14O. US Biological Life Sciences.
Worldwide
DCB
DCB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-Bis((9H-carbazol-9-yl)methyl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 166256-60-6. Molecular formula: C32H24N2. Mole weight: 436.55 g/mol. Product ID: ACM166256606. Alfa Chemistry ISO 9001:2015 Certified.
DCB
DCB (3,3-dichlorobenzaldazine) is an neutral allosteric modulator of the metabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5). DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3-dimethoxybenzaldazine (DMeOB) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6971-97-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103561.
DCB. Group: Biochemicals. Grades: Purified. CAS No. 6971-97-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DCB
DCB is an allosteric ligand for the metabotropic glutamate receptor mGlu5 that displays neutral modulation. It inhibits the modulation of mGlu5 by other allosteric modulators without affecting agonist-stimulated mGlu5 responses. Synonyms: [(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde; (E,E)-Bis[(3-chlorophenyl)methylidene]hydrazine. Grades: ≥98% by HPLC. CAS No. 6971-97-7. Molecular formula: C14H10Cl2N2. Mole weight: 277.15.
DCBA
DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72236-23-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136612.
dCBP-1
dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and ablates oncogenic enhancer activity driving MYC expression[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2484739-25-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134582.
dCBP-1
dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and can abolish the enhancer that drives MYC oncogene expression. As an efficient degrader of this unique class of acetyltransferases, dCBP-1 is a useful tool alongside domain inhibitors for dissecting the mechanism by which these factors coordinate enhancer activity in normal and diseased cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: dCBP-1; dCBP 1; dCBP1. Product Category: Others. Appearance: Solid powder. CAS No. 2484739-25-3. Molecular formula: C51H63F2N11O10. Mole weight: 1028.13. Purity: >98%. IUPACName: 5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1Hpyrazol-4-yl)-1(2H)-quinolinyl]-1-[1-[15-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-4-piperidinyl]-1,4,6,7-tetrahydro-N-methyl-. Canonical SMILES: O=C(N1CCC(N(C2CCN(C(CCOCCOCCOCCOCCNC3=CC4=C(C(N(C(CC5)C(NC5=O)=O)C4=O)=O)C=C3)=O)CC2)N=C6N7CCCC8=C7C=C(C(F)F)C(C9=CN(C)N=C9)=C8)=C6C1)NC. Product ID: ACM2484739253. Alfa Chemistry ISO 9001:2015 Certified. Categories: DCP 1700.
DCb-PCz
DCb-PCz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3-(9-Phenyl-9H-carbazol-3-yl)phenyl)-5H-pyrido[3,2-b]indole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2099149-76-3. Molecular formula: C35H23N3. Mole weight: 485.58 g/mol. Product ID: ACM2099149763. Alfa Chemistry ISO 9001:2015 Certified.
DCC-2618 inhibits normal and mutant KIT kinase at the nanomol level. The targets are wt c-KIT, c-KIT mutants, PDGFR alpha, PDGFR beta, KDR and cFMS. DCC-2618 inhibits mutant KIT in GIST patient cell line (GIST T1 pKIT western Ex11 deletion) at a IC 50 of 2 nM. Deciphera's technology has identified DCC-2618 as a molecule which can be developed as second line therapy for imatinib and sunitinib resistant GIST patients with the potential to progress to frontline GIST therapy. DCC-2618 has been designed to effectively inhibit the imatinib and sunitinib-sensitive KIT juxtamembrane domain mutants (JMD) as well as secondary resistant KIT kinase-domain mutants. DCC-2618 additionally targets PDGFR alpha oncogenic mutants. Synonyms: DCC2618; DCC 2618; c-Kit-IN-1; PDGFR inhibitor 1; N-[2,5-Difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide. Grades: >98%. CAS No. 1225278-16-9. Molecular formula: C26H21F2N5O3. Mole weight: 489.47.
DCC-3116
DCC-3116 is an orally active ULK1/2 inhibitor. DCC-3116 can inhibit autophagy in lung cancer cells by inhibiting KRASG12C signaling, thereby inhibiting the proliferation of lung cancer cells and exerting anti-cancer effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2543673-19-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-160699.
DC-Chol:DOPE (1:2) Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
DC-Chol:DOPE (50:50) Liposomes
Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy. Uses: Cancer research; target delivery. Group: Cationic liposome. Categories: Niosomes, ethosomes, and transfersomes.
DC-Chol hydrochloride
DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 ( IL-2 and IFN-γ ) and Th2 ( IL-5 ) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DC-Cholesterol hydrochloride. CAS No. 166023-21-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-137131.
DCC(NN"-Dicyclohexylcarbodiimide)
DCC(NN"-Dicyclohexylcarbodiimide). CAS No: 538-75-0
Sarchem Laboratories New Jersey NJ
DCEBIO
DCEBIO is a Ca2+ sensitive K+ channel (SKCa) agonist stimulating Cl- secretion via activation of hKCa3.1 (IK1) potassium channels and activation of an apical Cl- conductance. Synonyms: 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one; Dichloro-EBIO. Grades: ≥99% by HPLC. CAS No. 60563-36-2. Molecular formula: C9H8Cl2N2O. Mole weight: 231.08.
DCEBIO
DCEBIO. Group: Biochemicals. Grades: Purified. CAS No. 60563-36-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.