A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Dazoxiben hydrochloride is a potent and orally active thromboxane (TX) synthase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 37248. CAS No. 74226-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106067A.
Dazucorilant
Dazucorilant is a glucocorticoid receptor antagonist. Synonyms: {(4aR)-1-(4-fluorophenyl)-6-[4-(trifluoromethyl)benzene-1-sulfonyl]-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl}(pyridin-2-yl)methanone; (R)-(1-(4-fluorophenyl)-6-((4-(trifluoromethyl)phenyl)sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(pyridin-2-yl)methanone. CAS No. 1496508-34-9. Molecular formula: C29H22F4N4O3S. Mole weight: 582.58.
Dazucorilant
Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor ( GR ) modulator with a K i value ?1 nM in vitro. Dazucorilant can be used for the research of neurological disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CORT113176. CAS No. 1496508-34-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-132811.
DB07268 is a potent and selective JNK1 inhibitor. It has some degree of selectivity over quite a few kinases with the exceptions of CHK1, CK2, and PLK. Synonyms: DB07268; DB-07268; DB 07268. Grade: >98%. CAS No. 929007-72-7. Molecular formula: C17H15N5O2. Mole weight: 321.33.
DB18
DB18 is a potent and selective inhibitor of CDC2-like kinases (CLKs) , with IC 50 values in the range of 10-30 nM for CLK1, CLK2 and CLK4. DB18 has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2587177-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131978.
DB1976
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. It potently inhibits PU.1 binding and strongly inhibits the PU.1/DNA complex in vitro. DB1976 has apoptosis-inducing effect. Synonyms: 2,2'-(Selenophene-2,5-diyl)bis(1H-benzo[d]imidazole-6-carboximidamide); DB-1976; DB-1976. CAS No. 1557397-51-9. Molecular formula: C20H16N8Se. Mole weight: 447.35.
DB1976 dihydrochloride
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. It potently inhibits PU.1 binding and strongly inhibits the PU.1/DNA complex in vitro. DB1976 has apoptosis-inducing effect. Synonyms: DB1976 dihydrochloride; DB1976 (dihydrochloride); 2369663-93-2; DB1976 hydrochloride; DB1976 (hydrochloride); AKOS040732928; HY-135797A; CS-0114127; 2-[5-(6-carbamimidoyl-1H-benzimidazol-2-yl)selenophen-2-yl]-3H-benzimidazole-5-carboximidamide; dihydrochloride. Grade: ≥98%. CAS No. 2369663-93-2. Molecular formula: C20H18Cl2N8Se. Mole weight: 520.28.
DB1976 dihydrochloride
DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-?B affinity, KD of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2369663-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135797A.
DB-2073
DB-2073 is produced by the strain of Pseudomonas B-9004. It has the activity against streptococcus pneumoniae and tinea gypsum mold. Synonyms: 2-n-hexyl-5-n-propylresorcinol; Antibiotic DB 2073; 2-Hexyl-5-propyl-1,3-benzenediol; BRN 1964593. CAS No. 39341-78-1. Molecular formula: C15H24O2. Mole weight: 236.35.
DB2115 tertahydrochloride
DB2115 tertahydrochloride is a potent inhibitor of myeloid master regulator PU.1. CAS No. 1366126-19-3. Molecular formula: C32H34Cl4N8O2. Mole weight: 704.48.
DB2115 tertahydrochloride
DB2115 (tertahydrochloride) is a potent inhibitor of myeloid master regulator PU.1. DB2115 (tertahydrochloride) has the potential for researching cancers, including hematologic cancers such as leukemia, as well as other conditions associated with PU. 1 dysfunction (extracted from patent WO2017223260A1, compound DB2115) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1366126-19-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124676A.
DB2313
DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 ?M. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2170606-74-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124629.
DB2313
DB2313 is a potent inhibitor of the essential transcriptional factor PU.1 with IC50 value of 14 nM. Synonyms: 2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide). CAS No. 2170606-74-1. Molecular formula: C42H41FN8O2. Mole weight: 708.8.
DB2313 HCl
DB2313 is a potent inhibitor of the essential transcriptional factor PU.1 with IC50 value of 14 nM. Synonyms: DB2313 hydrochloride; DB 2313 hydrochloride; DB-2313 hydrochloride; DB2313 tetrahydrochloride; DB 2313 HCl; DB-2313 HCl. CAS No. 2170606-75-2. Molecular formula: C42H45Cl4FN8O2. Mole weight: 854.7.
DB28
DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16296-42-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W168754.
DB775
DB775 is a metabolite of DB289 (HY-14932) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 475976-08-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164025.
DB818
DB818 is a synthetic HOXA9 inhibitor that downregulates the expression of HOXA9 transcriptional target genes. Synonyms: DB 818; DB-818. Grade: >98%. CAS No. 790241-43-9. Molecular formula: C19H16N6S. Mole weight: 360.44.
DB818 dihydrochloride
DB818 dihydrochloride is the dihydrochloride salt form of DB818 (HY-122623). DB818 dihydrochloride is an inhibitor for Homeobox A9 (HOXA9). DB818 dihydrochloride reduces the formation of HOXA9-DNA complexes, inhibits the growth and induces apoptosis in AML cell lines OCI/AML3, MV4-11, and THP-1[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122623A.
DBA-DI
DBA-DI. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(5,9-dioxa-13b-boranaphtho[3,2,1-de]anthracen-7-yl)-10,15-diphenyl-10,15-dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2643306-48-1. Molecular formula: C54H32BN3O2. Mole weight: 765.66 g/mol. Product ID: ACM2643306481. Alfa Chemistry ISO 9001:2015 Certified. Categories: DBA (disambiguation).
D-b,b-Diethylalanine (D-3-Ethylnorvaline)
D-b,b-Diethylalanine (D-3-Ethylnorvaline). Group: Biochemicals. Alternative Names: D-3-Ethylnorvaline. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
DB-cAMP-AM
DB-cAMP-AM is a precursor of DB-cAMP. The dibutyryl cAMP is released after the metabolism of DB-cAMP-AM by esterases. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 159910-48-2. Molecular formula: C21H28N5O10P. Mole weight: 541.5.
DB-cCMP
DB-cCMP is a membrane-permeant prodrug of cCMP, the potential further second messenger. Synonyms: N4, 2'- O- Dibutyrylcytidine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. CAS No. 64649-87-2. Molecular formula: C17H23N3O9P · Na. Mole weight: 467.3.
DB-cGMP
DB-cGMP, an exceedingly compelling analogue of cyclic guanosine monophosphate (cGMP), a pivotal secondary messenger in myriad biological processes, serves as an invaluable tool in biomedical research. With a primary focus on unraveling the intricate role of cGMP in signal transduction pathways, cellular proliferation, and apoptosis, it facilitates the understanding of diseases stemming from aberrant cGMP signaling. Synonyms: N2, 2'- O- Dibutyrylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 51116-00-8. Molecular formula: C18H23N5O9P · Na. Mole weight: 507.4.
DBCO-acid
DBCO-acid. Uses: White to light yellow powder to crystal. Synonyms: 11,12-Didehydro-gamma-oxodibenz[b,f]azocine-5(6H)-butanoic acid. Grade: > 98.0 %. CAS No. 1353016-70-2. Molecular formula: C19H15NO3. Mole weight: 305.33.
DBCO-acid
DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-70-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-42972.
DBCO-amine
DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255942-06-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W000423.
DBCO-Amine Oxalate
A DBCO-containing reagent in the synthesis of high-generation polyester dendrimers. Synonyms: Azadibenzocyclooctyne-Amine Oxalate. Molecular formula: C18H16N2O.C2H2O4. Mole weight: 366.37.
DBCO-Biotin
DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1418217-95-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123916.
DBCO-Biotin
An intermidate used for antibody-drug conjugates. Synonyms: Azadibenzocyclooctyne-Biotin conjugate; N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide. CAS No. 1418217-95-4. Molecular formula: C28H30N4O3S. Mole weight: 502.63.
DBCO-CONH-PEG4-acid
DBCO-CONH-PEG4-acid. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1537170-85-6. Molecular formula: C30H36N2O8. Mole weight: 552.62. Purity: 95%+. Product ID: ACM1537170856. Alfa Chemistry ISO 9001:2015 Certified. Categories: DBCO-PEG4-acid.
DBCO-Cy3
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dye with excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DBCO-Sulfo-Cy3. CAS No. 1782950-79-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1069.
DBCO-CY3
A Cy3 fluorescent probe functionalized with a DBCO moiety for click chemistry. Uses: For industrial and laboratory use. Product Category: Fluorescein Dyes. Appearance: Purple solid. Molecular formula: C49H52N4O8S2. Mole weight: 889.09 g/mol. Purity: 0.95. Product ID: DYE-FLU-0059. Alfa Chemistry ISO 9001:2015 Certified.
DBCO-CY5
A Cy5 fluorescent probe functionalized with a DBCO moiety for click chemistry. Uses: For industrial and laboratory use. Product Category: Fluorescein Dyes. Appearance: Purple solid. Molecular formula: C51H54N4O8S2. Mole weight: 915.13 g/mol. Purity: 0.95. Product ID: DYE-FLU-0058. Alfa Chemistry ISO 9001:2015 Certified.
DBCO-CY7
A Cy7 fluorescent probe functionalized with a DBCO moiety for click chemistry. Uses: For industrial and laboratory use. Product Category: Fluorescein Dyes. Appearance: Purple solid. Molecular formula: C53H56N4O8S2. Mole weight: 941.17 g/mol. Purity: 0.95. Product ID: DYE-FLU-0057. Alfa Chemistry ISO 9001:2015 Certified.
DBCO-Doxorubicin Liposome (PEGylated)
This formulation is Doxorubicin Liposome (PEGylated) with the dibenzocyclooctyne (DBCO) group, which can react with an azide by click chemistry. The conjugation chemistry is based on the reaction of the DBCO reagent with an azide linker to form a stable triazole. Azide moiety can be on the antibody and DBCO moiety can be on liposome and vice versa. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
DBCO-dT CE Phosphoramidite
DBCO-dT CE Phosphoramidite is a copper-free click chemistry reagent designed for site-specific incorporation of dibenzocyclooctyne (DBCO) into oligonucleotides during solid-phase synthesis, enabling bioorthogonal conjugation with azide-functionalized molecules. The reagent features a DBCO moiety linked to a deoxythymidine (dT) base via a spacer arm, with a 3'-phosphoramidite group for efficient coupling in automated synthesizers. This phosphoramidite is ideal for preparing molecular probes, diagnostic assays, or therapeutic oligonucleotides requiring post-synthesis labeling. Synonyms: DBCO-dT Phosphoramidite. Grade: ≥95%. Molecular formula: C69H80N7O11P. Mole weight: 1214.41.
DBCO-Maleimide
DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395786-30-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-116270.
DBCO-NHCO-PEG12-biotin
DBCO-NHCO-PEG12-biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG12-biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C55H83N5O16S. Mole weight: 1102.34.
DBCO-NHCO-PEG2-Biotin
DBCO-NHCO-PEG2-Biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG2-Biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C36H45N5O6S. Mole weight: 675.84.
DBCO-NHCO-PEG6-Biotin
DBCO-NHCO-PEG6-Biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG6-Biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C43H59N5O10S. Mole weight: 838.02.
DBCO-NH-PEG12-Biotin
DBCO-NH-PEG12-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Azadibenzocyclooctyne-PEG12-Biotin conjugate. Grade: >95%. Molecular formula: C55H83N5O16S. Mole weight: 1102.34.
DBCO-NH-PEG2-Biotin
DBCO-NH-PEG2-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Azadibenzocyclooctyne-PEG2-Biotin conjugate. Grade: >95%. Molecular formula: C35H43N5O6S. Mole weight: 661.81.
DBCO-NH-PEG4-biotin
DBCO-NH-PEG4-biotin is a heterobifunctional PEG linker containing a biotin group and an alkyne group. The alkyne group can react with azide in various biomolecules via click chemistry. The PEG spacer increases membrane impermeability of molecules conjugated to biotin. Synonyms: Dibenzocyclooctyne-PEG4-Biotin conjugate; DBCO-PEG4-Biotin. Grade: >95%. CAS No. 1255942-07-4. Molecular formula: C39H51N5O8S. Mole weight: 749.92.
DBCO-NH-PEG6-Biotin
DBCO-NH-PEG6-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Azadibenzocyclooctyne-PEG6-Biotin conjugate. Grade: >95%. Molecular formula: C43H59N5O10S. Mole weight: 838.02.
DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-71-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-42973.
DBCO-NHS ester 2
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1384870-47-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115524.
DBCO-PEG12-NHS ester
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2093934-94-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140274.
DBCO-PEG2-NHS ester
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2585653-12-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151827.
DBCO-PEG3-Biotin
A biotinylation reagent containing a DBCO moiety for click chemistry. Grade: >95%. Molecular formula: C37H47N5O7S. Mole weight: 705.32.
DBCO-PEG3-FITC
A FITC fluorescent probe functionalized with a DBCO moiety for click chemistry. Uses: For industrial and laboratory use. Product Category: Fluorescein Dyes. Appearance: Yellow solid. Molecular formula: C48H44N4O10S. Mole weight: 868.95 g/mol. Purity: 0.95. Product ID: DYE-FLU-0060. Alfa Chemistry ISO 9001:2015 Certified.
DBCO-PEG3-NHS ester
DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163772-16-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-156507.
DBCO-PEG3-VC-Exatecan
DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2754384-70-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164792.
DBCO-PEG4-Biotin
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction [1]. DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255942-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-130809.
DBCO-PEG4-DBCO
DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2182601-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-130346.
DBCO-PEG4-Desthiobiotin
DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. DBCO-PEG4-Desthiobiotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2032788-37-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140301.
DBCO-PEG4-Desthiobiotin
DBCO-PEG4-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-PEG4-Desthiobiotin can be used in the synthesis of a series of PROTACs. Synonyms: DBCO-PEG4-Desthiobiotin; 2032788-37-5; AKOS040743203; BP-22451; HY-140301; CS-0114730; N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide. CAS No. 2032788-37-5. Molecular formula: C39H53N5O8. Mole weight: 719.87.
DBCO-PEG4-Eosin 5-isothiocyanate
DBCO-PEG4-Eosin 5-isothiocyanate is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections[1]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-159529.
DBCO-PEG4-GGFG-Dxd
DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG[1]. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2694856-51-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134723.
DBCO-PEG4-Maleimide
DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 25 mg. Product ID: HY-120770.
DBCO-PEG4-NHS ester
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1427004-19-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140272.
DBCO-PEG4-Val-Cit-PAB-MMAF
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244602-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130990.
DBCO-PEG4-VA-PBD
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241644-09-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133433.
DBCO-PEG4-VC-PAB-MMAE
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2129164-91-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136314.
DBCO-PEG4-vc-PAB-MMAF
DBCO-PEG4-vc-PAB-MMAF is a drug-linker conjugate for ADC by using Monomethylauristatin F (MMAF, a potent tubulin polymerization inhibitor), linked via DBCO-PEG4-vc-PAB. Molecular formula: C88H126N12O20. Mole weight: 1672.04.
DBCO-PEG5-Desthiobiotin
DBCO-PEG5-Desthiobiotin. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 2032788-37-5. Molecular formula: C39H53N5O8. Mole weight: 719.39. Purity: 95%+. Product ID: ACM2032788375. Alfa Chemistry ISO 9001:2015 Certified.
DBCO-PEG5-NHS ester
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1] [2]. DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2144395-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126885.
DBCO-Serinol Phosphoramidite
DBCO-Serinol Phosphoramidite is a quintessential reagent for biomedical research, a chemical compound that is omnipresent in the lab benches of esteemed molecular biologists. This versatile oligonucleotide synthesizer is engineered to conjugate with various biomolecules for a plethora of drug delivery and bioimaging applications. Synonyms: 3-Dimethoxytrityloxy-2-(6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-capramido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C54H61N4O7P. Mole weight: 909.08.