American Chemical Suppliers
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Product | Description | |
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Ezetimibe Impurity 5 Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L20) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H27F2NO3. Mole weight: 499.56. | |
Ezetimibe Impurity 8 Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L42) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione. Grades: > 95%. CAS No. 189028-93-1. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
Ezetimibe Impurity 8 Enantiomer Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L46) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone. Grades: > 95%. CAS No. 404874-93-7. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
Ezetimibe Impurity 9 Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. Grades: > 95%. CAS No. 272778-12-8. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98. | |
Ezetimibe Impurity B Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L14) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: methyl 5-(4-fluorophenyl)-5-hydroxypentanoate. Grades: > 95%. CAS No. 870634-36-9. Molecular formula: C12H15FO3. Mole weight: 226.25. | |
Ezetimibe Impurity (Tetrahydro-pyran-2-one) Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L35) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,6R)-6-(4-fluorophenyl)-3-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)tetrahydro-2H-pyran-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
Ezetimibe ketone Quick inquiry Where to buy Suppliers range | Ezetimibe ketone. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K. Grades: Highly Purified. CAS No. 191330-56-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H19F2NO3. US Biological Life Sciences. | Worldwide |
Ezetimibe Ketone Quick inquiry Where to buy Suppliers range | Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42. | |
Ezetimibe Lactam Cleaved Alcohol Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L23) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-Anhydro Ezetimibe Alcohol Impurity; (βR,γS)-γ-[(4-Fluorophenyl)amino]-β-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanol. Grades: > 95%. CAS No. 1374250-07-3. Molecular formula: C24H23F2NO2. Mole weight: 395.45. | |
Ezetimibe Phenexy Glucuronide Quick inquiry Where to buy Suppliers range | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe phenoxy Glucuronide. Grades: > 95%. CAS No. 190448-57-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
Ezetimibe Phenoxy Beta-D-Glucuronide Quick inquiry Where to buy Suppliers range | Ezetimibe Phenoxy Beta-D-Glucuronide. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 190448-57-8. IUPAC Name: (2S,3S,4S,5R,6S)-6-[4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid. Molecular formula: C30H29F2NO9. Mole weight: 585.55. Catalog: APS190448578. SMILES: O[C@@H] (CC[C@@H]1[C@H] (N (C1=O)c2ccc (F)cc2)c3ccc (O[C@@H]4O[C@@H] ([C@@H] (O)[C@H] (O)[C@H]4O)C (=O)O)cc3)c5ccc (F)cc5. Format: Neat. | |
Ezetimibe Phenoxy tert-Butyldiphenylsilyl Ether Quick inquiry Where to buy Suppliers range | Ezetimibe Phenoxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R, 4S) -1- (4-Fluorophenyl ) -3- [ (3S) -3- (4-fluorophenyl ) -3- hydroxypropyl ] -4- (4-tert-butyl diphenyl silyl oxyphenyl ) -2-azetidinone. Grades: Highly Purified. CAS No. 1042722-66-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Ezetimibe Related Impurity 6 Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L40) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((S)-3-(3-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
Ezetimibe Related Impurity 7 Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L41) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((E)-3-(3-fluorophenyl)allyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 204589-68-4. Molecular formula: C24H19F2NO2. Mole weight: 391.42. | |
Ezetimibe Ring-Open Impurity Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L15) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide. Grades: > 95%. CAS No. 1197811-72-5. Molecular formula: C24H23FNO3. Mole weight: 411.45. | |
Ezetimibe ring-opening dehydrate impurity Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L31) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (αR,βS)-β-[(4-Fluorophenyl)amino]-α-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanoic Acid. Grades: > 95%. CAS No. 1292292-63-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
Ezetimibe Tetrahydropyran Impurity Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide; SCH59566. Grades: > 95%. CAS No. 1296129-15-1. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
Ezetimibe Triol Impurity Quick inquiry Where to buy Suppliers range | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L48) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R,5R)-3-(4-fluorophenyl)-5-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-((S)-2-hydroxy-1-phenylethyl)-4-(4-hydroxyphenyl)piperidine-2,6-dione. Grades: > 95%. Molecular formula: C33H30F2N2OS. Mole weight: 572.61. | |
Ezh2 Inhibitor II, EI1(Enhancer of Zested Homolog 2 Inhibitor II, HMTase Inhibitor XI, 6-Cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide) Quick inquiry Where to buy Suppliers range | A cell-permeable indolocarboxamide compound that acts as a potent and selective inhibitor against Ezh2/PRC2 (Polycomb repressive complex 2; Ezh2 / SUZ12 / EED / AEBP2 / RbAP48) HMTase activity (IC50/substrate = 15nM/H3K27me021-44 and 13nM/H3K27me221-44, respectively, against human wt or Y641F Ezh2-containing PRC2; [SAM] = 1uM) in a cofactor SAM-competitive manner, while inhibiting Ezh1/PRC2 only at much higher concentrations (IC50 = 1.34uM) and exhibiting no potency toward CARM 1, Dot1L, G9a, MLL, NSD3, Set7/9, SETD2, SETD8, SmyD2, or Suv39H2 (IC50 >100uM). Shown to suppress cellular H3K27 dimethylation and trimethylation (1 to 10uM) in DLBCL cultures and exhibit antiproliferation activity against DLBCL cell lines with wt or mutant Ezh2 (3.3uM to 10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Primary Target: Ezh2/PRC2. US Biological Life Sciences. | Worldwide |
Ezlopitant Quick inquiry Where to buy Suppliers range | Ezlopitant, also known as CJ-11,974, is a NK1 receptor antagonist. It has antiemetic and antinociceptive effects. Synonyms: CJ 11,974; CJ-11974; CJ11974; (7S,8S)-7-[di(phenyl)methyl]-N-[(2-methoxy-5-propan-2-ylphenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine. CAS No. 147116-64-1. Molecular formula: C31H38N2O. Mole weight: 454.66. | |
EZM 2302 Quick inquiry Where to buy Suppliers range | EZM 2302 Inhibitor. Uses: Scientific use. Product Category: T5605. CAS No. 1628830-21-6. | |
Ezomycin A1 Quick inquiry Where to buy Suppliers range | Ezomycin A1 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 39422-19-0. Molecular formula: C26H38N8O15S. Mole weight: 734.69. | |
Ezomycin A2 Quick inquiry Where to buy Suppliers range | Ezomycin A2 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 54328-22-2. Molecular formula: C19H26N6O12. Mole weight: 530.44. | |
Ezomycin B2 Quick inquiry Where to buy Suppliers range | Ezomycin B2 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 57973-16-7. Molecular formula: C19H25N5O13. Mole weight: 531.43. | |
Ezomycin D2 Quick inquiry Where to buy Suppliers range | Ezomycin D2 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 57973-11-2. Molecular formula: C19H27N5O14. Mole weight: 549.44. | |
EZP-1-Slag Quick inquiry Where to buy Suppliers range | EZP-1-Slag. Uses: For analytical and research use. Group: Process Materials, Geological, Cement & Soils. Catalog: APS008055. Shipping: Room Temperature. | |
EZP-2-Slag Quick inquiry Where to buy Suppliers range | EZP-2-Slag. Uses: For analytical and research use. Group: Process Materials, Geological, Cement & Soils. Catalog: APS008056. Shipping: Room Temperature. | |
EZP-3-Slag Quick inquiry Where to buy Suppliers range | EZP-3-Slag. Uses: For analytical and research use. Group: Process Materials, Geological, Cement & Soils. Catalog: APS008057. Shipping: Room Temperature. | |
Ezrin Inhibitor, NSC668394 (7- (3, 5-dibromo-4-hydroxyphenethylamino) quinoline-5, 8-dione) Quick inquiry Where to buy Suppliers range | A cell-permeable, quinoline that binds directly to ezrin (=12.6uM) in a reversible manner, and inhibits PKC?-mediated ezrin phosphorylation at Thr567 (IC50=8.1uM) and ezrin-actin binding, in vitro. It also inhibits murine osteosarcoma K7M2 cell invasion in a monolayer of HUVEC cells, dose-dependently, from 1 to 10uM. At 10uM, it causes a unique developmental defect in zebrafish, characterized by reduced motility of eye progenitor cells. Furthermore, this small molecule prevents metastatic growth in an ex vivo mouse lung organ culture assay at 10uM and attenuates ezrin-dependent OS metastatic growth in mouse lung model in vitro at 2.26mg/kg/day. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
E,Z-trans-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid Quick inquiry Where to buy Suppliers range | E,Z-trans-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is the photolysis product of Permethrin, which is a medication and an insecticide used to treat scabies and lice. Synonyms: E,Z-trans-3-(2-Chlorovinyl)-2,2-dimethylcyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 3-[(1E)-2-chloroethenyl]-2,2-dimethyl-, (1R,3S)-rel-; rel-(1R,3S)-3-((E)-2-chlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 3-(2-chloroethenyl)-2,2-dimethyl-, [1α,3β(E)]-. Grades: 98%. CAS No. 61914-45-2. Molecular formula: C8H11ClO2. Mole weight: 174.62. | |
Ezurpimtrostat Quick inquiry Where to buy Suppliers range | Ezurpimtrostat is a palmitoyl protein thioesterase 1 (PPT-1) inhibitor. Synonyms: 4-(4-(tert-butylamino)piperidin-1-yl)-N-(4-chlorobenzyl)quinolin-2-amine. CAS No. 1914148-72-3. Molecular formula: C25H31ClN4. Mole weight: 423.00. | |
Ezutromid Quick inquiry Where to buy Suppliers range | Ezutromid, also known as BMN-195 and SMTC-1100, is an orally bioavailable and non-toxic small molecule that transcriptionally upregulates the utrophin gene (EC50= 0.4 uM), increasing both utrophin mRNA and protein. It significantly reduces dystrophin-deficient muscle pathology in vivo. Synonyms: 5-(ethylsulfonyl)-2-(naphthalen-2-yl)benzo[d]oxazole; BMN-195; BMN 195; BMN195; SMTC-1100; SMTC1100; SMTC 1100; VOX-C1100; Ezutromid. CAS No. 945531-77-1. Molecular formula: C19H15NO3S. Mole weight: 337.39. |