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Fmoc-nalpha-methyl-n-im-trityl-l-histidine (FMOC-His(Trt)-OH) is a derivative of the amino acid Histidine. It is used as a building block for the synthesis of peptides and proteins. Histidine is a non-polar, essential amino acid involved in many biological processes such as the biosynthesis of proteins, metal ion binding, and catalysis in enzyme reactions. FMOC-His(Trt)-OH contains a 9-fluorenylmethyloxycarbonyl (Fmoc) protecting group on the amino terminus and a trityl (Trt) protecting group on the imidazole nitrogen. Uses: Fmoc-his(trt)-oh is mainly used as a starting material for the synthesis of peptides and proteins. it is used in spps for the incorporation of histidine residues in the peptide sequence. the resulting peptides and proteins have various applications in scientific experiments, including drug discovery and development, vaccine development, and biological research. Group: Amino acids. Alternative Names: FMOC-His(Trt)-OH. CAS No. 1217840-61-3. Molecular formula: C41H35N3O4. Mole weight: 633.7. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-(1-tritylimidazol-4-yl)propanoic acid. Canonical SMILES: CN (C (CC1=CN (C=N1)C (C2=CC=CC=C2) (C3=CC=CC=C3)C4=CC=CC=C4)C (=O)O)C (=O)OCC5C6=CC=CC=C6C7=CC=CC=C57. Density: 1.2±0.1 g/cm3. Catalog: ACM1217840613.
Fmoc-Nalpha-methyl-O-methyl-L-Tyrosine
Fmoc-Nalpha-methyl-O-methyl-L-Tyrosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences.
Fmoc-N-amido-PEG12-propionic acid is a PEG linker containing a protected amino group and a carboxylic acid. The carboxylic acid can be reacted with amino groups in the presence of activators. Synonyms: Fmoc-N-amido-PEG12-acid; Fmoc-NH-PEG12-CH2CH2COOH; Fmoc-PEG12-propionic acid; (Fmoc-amino)-PEG12-C2-Carboxylic Acid; 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oic acid; O-(N-Fmoc-2-aminoethyl)-O'-(2-carboxyethyl)-undecathyleneglycol; 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 1-(9H-Fluoren-9-ylmethyl)-5,8,11,14,17,20,23,26,29,32,35,38-dodecaoxa-2-azahentetracontanedioate. Grades: ≥99%. CAS No. 1952360-91-6. Molecular formula: C42H65NO16. Mole weight: 839.96.
Di-Me L-lysine derivative. The methylation of lysine in histone tails is a common posttranslational modification that functions in histone-regulated chromatin condensation, with binding of methylated lysine occurring in aromatic pockets on chromodomain proteins. Synonyms: Fmoc-L-Lys(Me)2-OH HCl; Fmoc-N',N'-dimethyl-L-lysine hydrochloride; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(dimethylamino)hexanoic acid hydrochloride; (2S)-6-(dimethylamino)-2-(9H-fluoren-9-lmethoxycarbonylamino)hexanoic acid hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 252049-10-8. Molecular formula: C23H28N2O4·HCl. Mole weight: 432.95.
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1952360-91-6. Pack Sizes: 250 mg; 1 g. Product ID: HY-135821.
Fmoc-NH-PEG4-CH2COOH
Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Fmoc peg linkers. Alternative Names: 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid. CAS No. 437655-95-3. Molecular formula: C25H31NO8. Mole weight: 473.5. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (9H-Fluoren-9-ylmethoxycarbonylamino) ethoxy]ethoxy]ethoxy]ethoxy]acetic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NCCOCCOCCOCCOCC (=O)O. Density: 1.235±0.06 g/cm3. Catalog: ACM437655953.
Fmoc-NH-PEG8-CH2COOH
Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 868594-52-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133063.
TentaGel resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which poly(ethylene glycol) (PEG or POE) is grafted. Synonyms: TentaGel XV RAM; 4-[ (2, 4-Dimethoxyphenyl) -N- (9-fluorenylmethoxycarbonyl) aminomethyl]phenoxyacetamido polyethyleneglycol resin.
Fmoc-N-im-trityl-L-Histidine (Fmoc-L-His(Trt)-OH)
5g Pack Size. Group: Amino Acids. Formula: C40H33N3O4. CAS No. 109425-51-6. Prepack ID 90028506-5g. Molecular Weight 619.71. See USA prepack pricing.
Fmoc-N-(isobutyl)glycine
Fmoc-N-(isobutyl)glycine. Group: Biochemicals. Alternative Names: Fmoc-N-(isobutyl)-Gly-OH; Fmoc-Nleu-OH. Grades: Highly Purified. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Fmoc-N-(isobutyl)glycine 99+% (HPLC)
Fmoc-N-(isobutyl)glycine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Fmoc-N-isobutyl-hydroxylamine
Fmoc-N-isobutyl-hydroxylamine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Fmoc-Nle-OH
Standard building block for introduction of norleucine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Nle-OH, N-α-Fmoc-L-norleucine. CAS No. 77284-32-3. Molecular formula: C21H23NO4. Mole weight: 353.41. Catalog: ACM77284323.
Fmoc-N-Me-3-(4-py)-L-Ala
Fmoc-N-Me-3-(4-py)-L-Ala, a synthetic molecule, finds widespread use in the synthesis of peptides and proteins. Owing to its crucial role as a fundamental building block in solid-phase peptide synthesis, it has emerged as a potent weapon in the battle against numerous human maladies such as cancer and infectious diseases. With versatile functionality and chemical reactivity, the compound facilitates modifications and attachment to the peptide chain, rendering it a prized asset in the biomedical industry and a tool much sought after by researchers. Synonyms: Fmoc-N(Me)4Pal-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(pyridin-4-yl)propanoic acid. CAS No. 2381854-90-4. Molecular formula: C24H22N2O4. Mole weight: 402.4.
Fmoc-N-Me-Ala-OH can be used for peptide coupling reactions. Synonyms: Fmoc-N-methyl-L-alanine; (S)-2- ( ( ( (9H-Fluoren-9-yl)methoxy)carbonyl) (methyl)amino)propanoic acid; Fmoc-Nalpha-methyl-L-alanine; Fmoc-L-MeAla-OH; Fmoc-N-Methyl-Ala-OH; Fmoc-N-a-methyl-L-alanine. Grades: ≥99% by HPLC. CAS No. 84000-07-7. Molecular formula: C19H19NO4. Mole weight: 325.36.
Fmoc-N-Me-Ala-OH
Building block for introduction of N-α-methyl-alanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-N-Me-Ala-OH, N-α-Fmoc-N-α-methyl-L-alanine. CAS No. 84000-07-7. Mole weight: 325.36. Catalog: ACM84000077.
Fmoc-N-Me-Ala-OH
Fmoc-N-Me-Ala-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction. Uses: Scientific research. Group: Signaling pathways. CAS No. 84000-07-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W008235.
Fmoc-N-Me-Arg(Pbf)-OH
Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging [1]. Uses: Scientific research. Group: Peptides. CAS No. 913733-27-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-137002.
Fmoc protected N-methyl amino acid suitable for solid phase peptide synthesis. N-methyl amino acids have been shown to improve proteolytic stability of peptides. Group: Biochemicals. Alternative Names: N-α-Fmoc-N-α-methyl-L-aspartic acid β-tert butyl ester. Grades: Purified. CAS No. 152548-66-8. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
Worldwide
Fmoc-N-Me-Asp(OtBu)-OH
Fmoc-N-Me-Asp(OtBu)-OH is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 152548-66-8. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-W013740.