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FMOC-Lys(5-FAM)-OH is a building block for in-sequence Lysine labeling by FAM. FAM is a commonly used donor dye for preparing FRET peptides. Uses: Peptide synthesis. Product Category: Amino Acids. CAS No. 1242933-88-5. Molecular formula: C42H34N2O10. Mole weight: 726.7. Purity: Peak Area by HPLC ≥90%. Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CCCCNC(=O)C4=CC5=C(C=C4)C6(C7=C(C=C(C=C7)O)OC8=C6C=CC(=C8)O)OC5=O)C(=O)O. Product ID: ACM1242933885. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Ac)-OH
Building block for introduction of N-ε-acetyl-lysine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Ac)-OH, N-α-Fmoc-N-ε-acetyl-L-lysine. Product Category: Amino Acids. CAS No. 159766-56-0. Molecular formula: C23H26N2O5. Mole weight: 410.46. Product ID: ACM159766560-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Ac)-OH
Fmoc-Lys(Ac)-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 159766-56-0. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W008986.
Fmoc-Lys(Alloc)-OH
Orthogonally-protected building block for the synthesis of branched and cyclic peptides and peptides modified at the Lys side chain by Fmoc SPPS. The Alloc group can be selectively removed in the presence of standard Fmoc- and t-butyl-based protecting groups by treatment with Pd(Ph3P)4/CHCl3/AcOH/NMM. Uses: Peptide synthesis. Additional or Alternative Names: Nα-Fmoc-Nε-Alloc-L-lysine. Product Category: Amino Acids. CAS No. 146982-27-6. Molecular formula: C25H28N2O6. Mole weight: 452.5. Canonical SMILES: OC(=O)[C@H](CCCCNC(=O)OCC=C)NC(=O)OCC1c2ccccc2-c3ccccc13. Product ID: ACM146982276. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6-{[(prop-2-en-1-yloxy)carbonyl]amino}hexanoic acid.
Fmoc-Lys(Alloc)-OH
Fmoc-Lys(Alloc)-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 146982-27-6. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W010862.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Biocytin-β-Ala-Wang-PEG Resin; N-β-[N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-(biotinyl)-L-lysyl]-β-alanine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Lys(biotin)-OH
A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(biotin)-OH, N-α-Fmoc-N-ε-biotinyl-L-lysine. Product Category: Amino Acids. CAS No. 146987-10-2. Molecular formula: C31H38N4O6S. Mole weight: 594.72. Purity: Peak Area by HPLC ≥90%. Canonical SMILES: C1C2C(C(S1)CCCCC(=O)NCCCCC(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)NC(=O)N2. Density: 1.3±0.1 g/cm3. Product ID: ACM146987102. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Biotin)-OH
Fmoc-Lys(Biotin)-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 146987-10-2. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W010721.
Fmoc-Lys(biotin-PEG12)-OH
Fmoc-Lys (biotin-PEG12)-OH is a Lysine embedded biotinylation reagent containing a carboxylic group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Fmoc group can be removed under basic condition to obtain the free amine which can be used for further conjugations. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. Please contact us for GMP-grade inquiries. Grade: 0.98. Molecular formula: C58H91N5O19S. Mole weight: 1194.5.
Fmoc-Lys (biotin-PEG4)-OH
Fmoc-Lys (biotin-PEG4)-OH is a polyethylene glycol (PEG)-based PROTAC linker. Fmoc-Lys (biotin-PEG4)-OH can be used in the synthesis of a series of PROTACs. CAS No. 1334172-64-3. Molecular formula: C42H59N5O11S. Mole weight: 842.01.
Fmoc-Lys(Biotinyl-Aca-Aca)
Fmoc-Lys(Biotinyl-Aca-Aca).
Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH
A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS., in which the biotin is separated from the lysine side-chain by a 6 C-atom spacer. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH, N-α-Fmoc-N-ε-(biotinylcaproyl)-L-lysine. Product Category: Amino Acids. CAS No. 160158-05-4. Mole weight: 707.88. Product ID: ACM160158054-1. Alfa Chemistry ISO 9001:2015 Certified.
Building block for the preparation of fluorescent labelled peptides. The anthranilic acid attached at the side-chain of lysine is highly sensitive and its fluorescence spectrum does not overlap with those of Trp, Phe, and Tyr. Uses: Peptide synthesis. Additional or Alternative Names: Boc-Abz-(Fmoc-Lys-OH)#Fmoc-ablysin(Boc)-OH. Product Category: Amino Acids. CAS No. 159322-59-5. Molecular formula: C33H37N3O7. Mole weight: 587.6. Purity: Peak Area by HPLC ≥90%. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]benzoyl]amino]hexanoic acid. Canonical SMILES: CC(C)(C)OC(=O)NC1=CC=CC=C1C(=O)NCCCCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Density: 1.3±0.1 g/cm3. Product ID: ACM159322595-1. Alfa Chemistry ISO 9001:2015 Certified.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Lys(Boc)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-(t-butoxycarbonyl)-L-lysine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-lys(boc)(me)-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fmoc-Lys(Boc)(Me)-OH;Nalpha-Fmoc-nepsiloN-metyl-nepsilon-Boc-L-lysine. Product Category: Heterocyclic Organic Compound. CAS No. 956195-85-5. Molecular formula: C27H34N2O6. Purity: 0.96. Product ID: ACM956195855. Alfa Chemistry ISO 9001:2015 Certified. Categories: 951695-85-5.
Fmoc-Lys(Boc,Me)-OH
Fmoc-Lys(Boc,Me)-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 951695-85-5. Pack Sizes: 250 mg; 1 g. Product ID: HY-66024.
5g Pack Size. Group: Amino Acids. Formula: C26H32N2O6. CAS No. 71989-26-9. Prepack ID 90029040-5g. Molecular Weight 468.54. See USA prepack pricing.
Fmoc-Lys(Boc)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of lysine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Boc)-OH, N-α-Fmoc-N-ε-t.-Boc-L-lysine. Product Category: Amino Acids. CAS No. 71989-26-9. Molecular formula: C26H32N2O6. Mole weight: 468.54. Product ID: ACM71989269. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Boc)-OH
Fmoc-Lys(Boc)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 71989-26-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C26H32N2O6. US Biological Life Sciences.
Worldwide
Fmoc-Lys(Boc)-OH (1-13C)
L-Lysine N-Fmoc/Boc (1-13C) is a protected amino acid used to synthesize isotope-labeled peptides for MS-based protein quantitation. Uses: Biomolecular nmr, proteomics. Additional or Alternative Names: N-α-Fluorenylmethoxycarbonyl-N-ε-tert-butoxycarbonyl-L-lysine. Product Category: Amino Acids. CAS No. 1242058-72-5. Molecular formula: Boc-NH(CH2)4CH(NH-Fmoc)13COOH. Mole weight: 469.5. Purity: Peak Area by HPLC ≥95%. ECNumber: 276-256-4 (Unlabeled). Product ID: ACM1242058725-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Boc)-OH-[1-13C]
Fmoc-Lys(Boc)-OH-[1-13C] is the labelled analogue of Fmoc-Lys(Boc)-OH. Fmoc-Lys(Boc)-OH is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use. Synonyms: L-Lysine-1-13C-alpha-N-FMOC, epsilon-N-T-BOC. Grade: 98% by CP; 99% atom 13C. Molecular formula: C25[13C]H32N2O6. Mole weight: 469.53.
Fmoc-Lys(Boc)-OH-[13C6]
Fmoc-Lys(Boc)-OH-[13C6] is the labelled analogue of Fmoc-Lys(Boc)-OH. Fmoc-Lys(Boc)-OH is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use. Synonyms: L-Lysine-13C6-alpha-N-FMOC, epsilon-N-T-BOC. Grade: 98% by CP; 99% atom 13C. Molecular formula: C20[13C]6H32N2O6. Mole weight: 474.49.
Fmoc-Lys(Boc)-OH-15N2
Fmoc-Lys(Boc)-OH-15N2. Uses: Peptide synthesis. Additional or Alternative Names: L-Lysine-15N2, α-N-Fmoc, ε-N-t-Boc. Product Category: Amino Acids. CAS No. 1217447-72-7. Molecular formula: (Boc-15NH)(CH2)4CH(15NH-Fmoc)CO2H. Mole weight: 468.54. Canonical SMILES: CC(C)(C)OC(=O)[15NH]CCCC[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM1217447727. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Boc)-OH (U-13C6, U-15N2)
Fmoc-Lys(Boc)-OH (U-13C6, U-15N2). Uses: Peptide synthesis. Additional or Alternative Names: L-Lysine-13C6.15N2, α-N-Fmoc, ε-N-t-Boc. Product Category: Amino Acids. CAS No. 850080-89-6. Molecular formula: Boc-15NH-(13CH2)413CH(15NH-Fmoc)13COOH. Mole weight: 476.5. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: CC(C)(C)OC(=O)[15NH][13CH2][13CH2][13CH2][13CH2][13C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)[13C](O)=O. Product ID: ACM850080896-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Boc)-ol-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide. Uses: Scientific research. Group: Peptides. CAS No. 957780-54-0. Pack Sizes: 1 g; 5 g. Product ID: HY-P2389.
Fmoc-Lys(Boc)-Ser[Psi(Me,Me)Pro]-OH
Fmoc-Lys(Boc)-Ser[Psi(Me,Me)Pro]-OH. Synonyms: Fmoc-Lys(Boc)-Ser[Ψ(Me,Me)Pro]-OH; (S)-3-[Nα-(9-Fluorenylmethyloxycarbonyl)-Nε-tert-butyloxycarbonyl-L-lysinyl]-2,2-dimethyloxazolidine-4-carboxylic acid. Grade: 95-101% (Assay by titration). CAS No. 957780-54-0. Molecular formula: C32H41N3O8. Mole weight: 595.69.
Fmoc-Lys(Boc)-Ser[Psi(Me,Me)Pro]-OH 98+% (HPLC)
Fmoc-Lys(Boc)-Ser[Psi(Me,Me)Pro]-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 957780-54-0. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-Lys(Boc)-Thr(psiMe,Mepro)-OH
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Lys-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Boc)-Thr(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 911838-56-7. Mole weight: 609.71. Product ID: ACM911838567-1. Alfa Chemistry ISO 9001:2015 Certified.
A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc SPPS. The Dabcyl group quenches the fluorescence of EDANS, Mca, TET, JOE, FAM fluorophores, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Dabcyl)-OH. Product Category: Amino Acids. CAS No. 146998-27-8. Molecular formula: C36H37N5O5. Mole weight: 619.71. Product ID: ACM146998278-1. Alfa Chemistry ISO 9001:2015 Certified.
Quasi-orthogonally-protected Lys derivative for Fmoc SPPS. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF. When removing Dde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Lys(Dde) has been employed in the following applications: synthesis of branched peptides and di-epitopic peptides ; preparation of MAP core molecules and lipo-MAPs; construction of cyclic peptides , TASP molecules , templates for combinatorial chemistry and synthetic proteins ; preparation of peptides modified at the lysine side-chain.It has been reported that Dde can migrate from the side-chain of Lys to the unprotected side-chain of another Lys residue , and from the β-amino group to the α-amino group of Dpr. In the former instance, this problem can be overcome by using Fmoc-Lys(ivDde)-OH or using DBU/DMF (2:98) for Fmoc group removal.Full orthogonality of Dde with Fmoc has recently been demonstrated when hydroxylamine is used for Dde removal. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Dde)-OH, N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine. Product Category: Amino Acids. CAS No. 150629-67-7. Molecular formula: C31H36N2O6. Mole weight: 532.63. Product ID: ACM150629677. Alfa Chemistry ISO 9001:2015
Fmoc-Lys(iPr, Boc)-OH is used for incorporation of N-d-isopropyl-lysine (Lys(iPr)) during Fmoc SPPS. Lys(iPr) has been utilized in the GnRH antagonist Degarelix and the LHRH antagonist Antide. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(iPr,Boc)-OH, N-α-Fmoc-N-ε-isopropyl-N-ε-t.-Boc-L-lysine. Product Category: Amino Acids. CAS No. 201003-48-7. Mole weight: 510.62. Product ID: ACM201003487-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(ivDde)-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Lys(ivDde)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-N-ε-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-L-lysine p-methoxybenzyl alcohol polyethyleneglycol resin.
This orthogonally-protected lysine derivative is based on the hindered Dde variant ivDde. It has very similar chemical properties to Fmoc-Lys(Dde)-OH, except that the side-chain ivDde group is considerably more stable to piperidine than Dde, and is less prone to migrate from protected to unprotected lysine side-chains.When removing ivDde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(ivDde)-OH, N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-lysine. Product Category: Amino Acids. CAS No. 204777-78-6. Molecular formula: C34H42N2O6. Mole weight: 574.71. IUPACName: (2S)-6-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid. Canonical SMILES: CC(C)CC(=C1C(=O)CC(CC1=O)(C)C)NCCCCC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Density: 1.2±0.1 g/cm3. Product ID: ACM204777786. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(IvDde)-OH
The ivDde protective group possesses higher orthogonality regarding Boc and Fmoc in comparison to Dde. Synonyms: Fmoc-L-Lys(ivDde)-OH; (S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-((1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)-3-Methylbutyl)Amino)Hexanoic Acid; N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-Dioxocyclohex-1-Ylidene)-3-Methylbutyl]-L-Lysine. Grade: ≥ 98%. CAS No. 204777-78-6. Molecular formula: C34H42N2O6. Mole weight: 574.72.
Fmoc-Lys(Me)2-OH HCl
Fmoc-Lys(Me)2-OH HCl. Group: Biochemicals. Alternative Names: N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6,N6-dimethyl-L-lysine hydrochloride; (S)-N-Fmoc-N',N''-dimethyl-L-lysine hydrochloride. Grades: Highly Purified. CAS No. 252049-10-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C23H29ClN2O4. US Biological Life Sciences.
Worldwide
Fmoc-Lys(Me)2-OH · HCl
A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Lys(Me)2-OH HCl, N-α-Fmoc-N-ε-dimethyl-N-L-lysine · hydrochloride. Product Category: Amino Acids. CAS No. 252049-10-8. Molecular formula: C23H28N2O4·HCl. Mole weight: 396.4·36.5. Product ID: ACM252049108. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Lys(Me)2-OH hydrochloride
Fmoc-Lys(Me)2-OH HCl is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 252049-10-8. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-66025.