A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Also acts on a number of other gibberellins. Group: Enzymes. Synonyms: gibberellin 2β-hydroxylase. Enzyme Commission Number: EC 1.14.11.13. CAS No. 85713-20-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0629; gibberellin 2β-dioxygenase; EC 1.14.11.13; 85713-20-8; gibberellin 2β-hydroxylase. Cat No: EXWM-0629.
gibberellin 3β-dioxygenase
Requires Fe2+ and ascorbate. Group: Enzymes. Synonyms: gibberellin 3β-hydroxylase; (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3β-hydroxylating). Enzyme Commission Number: EC 1.14.11.15. CAS No. 120860-89-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0631; gibberellin 3β-dioxygenase; EC 1.14.11.15; 120860-89-1; gibberellin 3β-hydroxylase; (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3β-hydroxylating). Cat No: EXWM-0631.
gibberellin-44 dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: oxygenase, gibberellin A44 oxidase; (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase. Enzyme Commission Number: EC 1.14.11.12. CAS No. 112198-85-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0628; gibberellin-44 dioxygenase; EC 1.14.11.12; 112198-85-3; oxygenase, gibberellin A44 oxidase; (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase. Cat No: EXWM-0628.
Gibberellin A1
Gibberellin A1 is a kind of plant hormones. Gibberellin A1 is a growth-promoting acids isolated from immature seed of Phaseolus multiflorus [1]. Uses: Scientific research. Group: Natural products. CAS No. 545-97-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N7443.
Gibberellin A4 is a derivative of Gibberellic Acid. It is a plant growth hormone that regulates growth and differentiation of plant cells for elongation, germination and enzyme induction. Synonyms: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibbane-1,10-dicarboxylic Acid Deriv.; GA4; 2β,4a-Dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic Acid; (1α, 2β, 4aα, 4bβ, 10β)-2, 4a-Dihydroxy-1-methyl-8-methylene-gibbane-1, 10-dicarboxylic Acid. Grades: > 95%. CAS No. 468-44-0. Molecular formula: C19H24O5. Mole weight: 332.40.
Gibberellin A4
Gibberellin A4 is a natural compound that can be isolated from Sphaceloma manihoticola. Gibberellin A4 is a causal agent of cassava superelongation disease [1]. Uses: Scientific research. Group: Natural products. CAS No. 468-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8440.
Gibberellin A44
Gibberellin A44. Uses: For analytical and research use. Group: Impurity standards. CAS No. 36434-15-8. Molecular Formula: C20H26O5. Mole Weight: 346.42. Catalog: APB36434158.
gibberellin A4 carboxyl methyltransferase
The enzyme also methylates gibberellins A34 (80%), A9 (60%), and A3 (45%) with significant activity. Group: Enzymes. Synonyms: GAMT2; gibberellin A4 O-methyltransferase. Enzyme Commission Number: EC 2.1.1.276. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1882; gibberellin A4 carboxyl methyltransferase; EC 2.1.1.276; GAMT2; gibberellin A4 O-methyltransferase. Cat No: EXWM-1882.
Gibberellin A5
Gibberellin A5. Group: Biochemicals. Alternative Names: 4a,7-Dihydroxy-1-methyl-8-methylene-4aα,4b β-Gibb-2-ene-1α,10 β-dicarboxylic Acid 1,4a-Lactone; GA5; GA5 (Gibberellin). Grades: Highly Purified. CAS No. 561-56-8. Pack Sizes: 25mg. Molecular Formula: C19H22O5, Molecular Weight: 330.37. US Biological Life Sciences.
Worldwide
Gibberellin A5
Gibberellin A5 is a plant hormone which promotes floral development but have little effect on stem elongation. Synonyms: C11871; (1R, 2R, 5S, 8S, 9S, 10R, 11R)-5-Hydroxy-11-Methyl-6-Methylidene-16-Oxo-15-Oxapentacyclo[9.3.2.1(5, 8).0(1, 10).0(2, 8)]Heptadec-12-Ene-9-Carboxylic Acid; 4a,7-Dihydroxy-1-methyl-8-methylene-4aα,4bβ-Gibb-2-ene-1α,10β-dicarboxylic Acid 1,4a-Lactone; GA5. Grades: > 95%. CAS No. 561-56-8. Molecular formula: C19H22O5. Mole weight: 330.38.
Gibberellin A7 is a natural product isolated from culture filtrates of the fungus Gibberella fujikuroi. Gibberellin A7 was shown to promote the growth and elongation of cells. Synonyms: 2,4a,4b,5,6,7,8,9,10,10a-Decahydro-2,4a-dihydroxy-1-methyl-8-methylene-1H-7,9a-methanobenz[a]azulene-1,10-dicarboxylic Acid 1,4a-Lactone; 2β,4a-Dihydroxy-1-methyl-8-methylene-4aα,4bβ-Gibb-3-ene-1α,10β-dicarboxylic Acid 1,4a-Lactone. Grades: > 95%. CAS No. 510-75-8. Molecular formula: C19H22O5. Mole weight: 330.38.
Gibberellin A72
Gibberellin A72. Group: Biochemicals. Alternative Names: 4a, 1- (Epoxymethano) -7, 9a-methanobenz [a]azuleneibbane-1, 10-dicarboxylic Acid Deriv.; GA72. Grades: Highly Purified. CAS No. 105593-21-3. Pack Sizes: 2.5mg. Molecular Formula: C19H24O7, Molecular Weight: 364.39. US Biological Life Sciences.
Gibberellin A8. Group: Biochemicals. Alternative Names: 2 β,3 β,4a,7-Tetrahydroxy-1-methyl-8-methylene-4aα,4b β-gibbane-1α,10 β-dicarboxylic Acid 1,4a-Lactone; Dodecahydro-2,3,4a,7-tetrahydroxy-1-methyl-8-methylene-7H-7,9a-methanobenz[a]azulene-1,10-dicarboxylic Acid 1,4a-Lactone; GA8. Grades: Highly Purified. CAS No. 7044-72-6. Pack Sizes: 10mg. Molecular Formula: C19H24O7, Molecular Weight: 364.39. US Biological Life Sciences.
Worldwide
Gibberellin A95
Gibberellin A95. Group: Biochemicals. Alternative Names: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibb-3-ene-1,10-dicarboxylic Acid Deriv.; GA95; Gibberellin GA95; NSC 224287. Grades: Highly Purified. CAS No. 78259-50-4. Pack Sizes: 50mg. Molecular Formula: C19H22O5, Molecular Weight: 330.37. US Biological Life Sciences.
Worldwide
Gibberellin A95
Gibberellin A95 is a derivative of Gibberelic Acid. It is a stereoisomer of Gibberelin A5. Synonyms: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibb-3-ene-1,10-dicarboxylic Acid Deriv.; GA95; NSC 224287. Grades: > 95%. CAS No. 78259-50-4. Molecular formula: C19H22O5. Mole weight: 330.38.
gibberellin A9 O-methyltransferase
The enzyme also methylates gibberellins A20 (95%), A3 (80%), A4 (69%) and A34 (46%) with significant activity. Group: Enzymes. Synonyms: GAMT1. Enzyme Commission Number: EC 2.1.1.275. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1881; gibberellin A9 O-methyltransferase; EC 2.1.1.275; GAMT1. Cat No: EXWM-1881.
gibberellin β-D-glucosyltransferase
Acts on the plant hormone gibberellin GA3 and related compounds. Group: Enzymes. Synonyms: uridine diphosphoglucose-gibberellate 7-glucosyltransferase; uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.176. CAS No. 99775-14-1,94489-97-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2401; gibberellin β-D-glucosyltransferase; EC 2.4.1.176; 99775-14-1,94489-97-1; uridine diphosphoglucose-gibberellate 7-glucosyltransferase; uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase. Cat No: EXWM-2401.
Gibberellin impurity 3
Gibberellin impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13744-18-8. Molecular Formula: C20H26O4. Mole Weight: 330.42. Catalog: APB13744188.
Gibberenone
Gibberenone. Uses: For analytical and research use. Group: Impurity standards. CAS No. 17924-92-4. Molecular Formula: C18H22O5. Mole Weight: 318.37. Catalog: APB17924924.
Gibbestatin B
It is produced by the strain of Streptomyces sp. C39. Gibbestatin B inhibits the expression of α-amylase induced by gibberellin in De-embryoned rice and barley (IC50 is 25-50 ppm, IC100 is 100-200 ppm), and has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi). Synonyms: Antibiotic 2-11-B. CAS No. 89687-34-3. Molecular formula: C22H26O6. Mole weight: 386.44.
Gibbestatin C
It is produced by the strain of Streptomyces sp. C39. It is a bioactive substance. Gibberellin C of 200 ppm has no inhibitory effect on α-amylase. It also has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi). Synonyms: 2-Hydroxypenyl Gibbestatin B. Molecular formula: C28H30O7. Mole weight: 478.53.
Giberellin A68
Giberellin A68. Group: Biochemicals. Alternative Names: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene Gibb-3-ene-1,10-dicarboxylic Acid Deriv.; GA68. Grades: Highly Purified. CAS No. 71177-41-8. Pack Sizes: 2.5mg. Molecular Formula: C19H22O6, Molecular Weight: 346.37. US Biological Life Sciences.
Worldwide
GIBH-130
GIBH-130 is an effective inhibitor of neuroinflammation. GIBH-130 significantly suppresses theIL-1βsecretion by activated microglia (IC50=3.4 nM). GIBH-13 constitutes a unique chemical probe for pathogenesis research and drug development of AD, and it also suggests microglia-based phenotypic screenings that target neuroinflammation as an effective and feasible strategy to identify novel anti-AD agents. Synonyms: (4-methyl-6-phenylpyridazin-3-yl)-(4-pyrimidin-2; -ylpiperazin-1-yl)methanone; (4-methyl-6-phenylpyridazin-3-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone; GIBH-130; GIBH130; GIBH 130. CAS No. 1252608-59-5. Molecular formula: C20H20N6O. Mole weight: 360.41.
Gidazepam
Gidazepam has a 3-fold higher affinity for MBR than for CBR (IC50= 710 and 2200 nmol/L, respectively). Uses: Anticonvulsants. Synonyms: 2-(7-bromo-2-oxo-5-phenyl-3H-1,4-benzodiazepin-1-yl)acetohydrazide; (1-hydrazinocarbonyl)-7-bromo-5-phenyl-1,2-dihydro-3H-1,4-benzodiazepine-2-one; gidazepam. CAS No. 129186-29-4. Molecular formula: C17H15BrN4O2. Mole weight: 387.23.
Gidazepam
Gidazepam is an agonist of GABA receptor channels ( GABA RCs ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gidasepam; Hidazepam; Hydazepam. CAS No. 129186-29-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00315.
Giemsa stain
Giemsa stain. Group: Biochemicals. Grades: Highly Purified. CAS No. 51811-82-6. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C14H14ClN3S. US Biological Life Sciences.
Worldwide
Giemsa stain
Giemsa stain can stain chromatin and nuclear membrane. Giemsa stain histopathologic detection of malaria and other microorganisms, such as Histoplasma, LeishmaniaToxoplasma, and Pneumocystis [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 51811-82-6. Pack Sizes: 1 g; 5 g. Product ID: HY-D0944.
Giemsa Stain
25g Pack Size. Group: Stains & Indicators. Formula: C14H14ClN3S. CAS No. 51811-82-6. Prepack ID 48872073-25g. Molecular Weight 291.8. See USA prepack pricing.
Giemsa Stain, Certified
Giemsa Stain, Certified. Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Heterocyclic Organic Compound. Alternative Names: UINTAHITE;GILSONITE RESIN;GILSONITE, UINTAHITE. CAS No. 12002-43-6. Molecular formula: N/A. Appearance: Dark brown to black crystalline solid. Nonconductor of electricity. Catalog: ACM12002436.
Gilsonite 12002-43-6
Gilsonite - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Gilteritinib
Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3 / AXL inhibitor with IC 50 s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP2215. CAS No. 1254053-43-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12432.
Gilteritinib
Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations. In invitro, among the 78 tyrosine kinases tested, ASP2215 inhibited FLT3, LTK, ALK, and AXL kinases by over 50% at 1 nM with an IC50 value of 0.29 nM for FLT3, approximately 800-fold more potent than for c-KIT, the inhibition of which is linked to a potential risk of myelosuppression. ASP2215 inhibited the growth of MV4-11 cells, which harbor FLT3-ITD, with an IC50 value of 0.92 nM, accompanied with inhibition of pFLT3, pAKT, pSTAT5, pERK, and pS6. ASP2215 decreased tumor burden in bone marrow and prolonged the survival of mice intravenously transplanted with MV4-11 cells. ASP2215 may have potential use in treating AML. Synonyms: Gilteritinib; ASP2215; ASP-2215; ASP 2215. CAS No. 1254053-43-4. Molecular formula: C29H44N8O3. Mole weight: 552.724.
Gilteritinib hemifumarate
Gilteritinib hemifumarate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1254053-84-3. Molecular Formula: C33H48N8O7. Mole Weight: 668.8. Catalog: APB1254053843.
Gilugel cao
Heterocyclic Organic Compound. Alternative Names: Castor Oil and Aluminum/Magnesium Hydroxide Stearate. CAS No. 128000-05-5. Molecular formula: C21H36N7O16P3S. Catalog: ACM128000055.
Gilvetmab
Gilvetmab is a potent caninized anti- PD-1 monoclonal antibody. gilvetmab blocks the interaction between PD-1 and its ligand PDL-1 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1808081-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99641.
Gilvocarcin E
It is produced by the strain of Streptomyces gilvotanareus, Str. anandii. It has anti-gram-positive bacterial activity and can inhibit sarcoma 180 and P388 leukemia cells. Synonyms: 8-Ethyl-4-(6-deoxy-α-L-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Anandimycin C; Toromycin C; dihydrotoromycin; 4-Fucofuranosyl-1-hydroxy-10,12-dimethoxy-8-ethyl-6H-benzo(d)naphtho(1,2b)pyran-6-one; 1,4-Anhydro-6-deoxy-1-(8-ethyl-1-hydroxy-10,12-dimethoxy-6-oxo-6H-benzo[d]naphtho[1,2-b]pyran-4-yl)hexitol. CAS No. 80937-34-4. Molecular formula: C27H28O9. Mole weight: 496.50.
Gilvocarcin M
It is produced by the strain of Streptomyces gilvotanareus, Str. anandii. It has anti-gram-positive bacterial activity and can inhibit sarcoma 180 and P388 leukemia cells. Synonyms: 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-; 4-(6-Deoxy-α-L-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Anandimycin B; ToroMycin B; Antibiotic 1072A. Grades: >95% by HPLC. CAS No. 77879-89-1. Molecular formula: C26H26O9. Mole weight: 482.48.
Gilvocarcin M (Anandimycin B, Toromycin B, Antibiotic 1072A)
Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp. Gilvocarcin M contains a methyl group in the 8-position and is less active than the vinyl analogue (gilvocarcin V), which is thought to act as an inhibitor of human topoisomerase II. Gilvocarcin M displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research on the gilvocarcins suggests that they act as photoactivated crosslinkers of DNA to histones. Group: Biochemicals. Alternative Names: Anandimycin B, Toromycin B, Antibiotic 1072A. Grades: Highly Purified. CAS No. 77879-89-1. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Gilvocarcin V
Antibiotic. Antitumor compound. Weakly active against Gram-positive bacteria and fungi. Mediates a unique cross-linking reaction between DNA and histone H3 by light. Single strand scission and covalent binding to DNA after photoactivation. Source:Streptomyces sp. Gö 3592. Group: Biochemicals. Alternative Names: 4-(6-Deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Antibiotic 1072B; NSC 338943; NSC 348115. Grades: Highly Purified. CAS No. 77879-90-4. Pack Sizes: 100ug, 250ug, 1mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
Gilvocarcin V
Gilvocarcin V is an antibiotic with antibacterial activity and can be isolated from Actinomycete. Gilvocarcin V also has anti-tumor activity and can be used in cancer research [1]. Uses: Scientific research. Group: Natural products. CAS No. 77879-90-4. Pack Sizes: 100 μg; 250 μg. Product ID: HY-129307.
Gilvocarcin V
It is produced by the strain of Streptomyces gilvotanareus, Str. anandii. It has anti-gram-positive bacteria, negative bacteria, fungal activity and can inhibit sarcoma 180 and P388 leukemia cells. Synonyms: DC-38-V; Anandimycin A; Toromycin; Antibiotic 1072B; Antibiotic B21085; Antibiotic DC 38A; Antibiotic DC 38V; 4-(6-Deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one; NSC 338943; NSC 348115. Grades: >95% by HPLC. CAS No. 77879-90-4. Molecular formula: C27H26O9. Mole weight: 494.49.
Gilvocarcin V (Anandimycin A, Toromycin B, Antibiotic 1072B)
Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp. Gilvocarcin V contains a vinyl group in the 8-position and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research on the gilvocarcins suggests that they act as photoactiviated crosslinkers of DNA to histones. Group: Biochemicals. Alternative Names: Anandimycin A, Toromycin B, Antibiotic 1072B. Grades: Highly Purified. CAS No. 77879-90-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Gilvusmycin
It is produced by the strain of Streptomyces sp. It is an antibiotic with strong anti-tumor activity. It can inhibit P388, K562, A431 and MKN28 cells with IC50 (ng/mL) of 0.08, 0.86, 0.72 and 0.75, respectively. Synonyms: 6-({6-[(6-acetyl-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl)carbonyl]-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl}carbonyl)-3-methyl-4,4a,5,6-tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-8(1H)-one. CAS No. 195052-09-6. Molecular formula: C38H34N6O8. Mole weight: 702.71.
Gimatecan
Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. Group: Inhibitors. Alternative Names: LBQ707; LBQ 707; LB-Q707; ST1481; ST1481; ST-1481; CPT 1847; CPT-1847; CPT1847; Gimatecan. CAS No. 292618-32-7. Molecular formula: C25H25N3O5. Mole weight: 447.4831 g/mol. Appearance: Solid powder. Purity: ≥98%. IUPACName: (4S)-11-((E)-((1,1-Dimethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione. Canonical SMILES: O=C1[C@] (O) (CC)C2=C (CO1)C (N3CC4=C (/C=N/OC (C) (C)C)C5=CC=CC=C5N=C4C3=C2)=O. Catalog: ACM292618327.
Gimatecan
Gimatecan is an orally bioavailable, semi-synthetic lipophilic analogue of camptothecin, a quinoline alkaloid extracted from the Asian tree Camptotheca acuminate, with potential antineoplastic and antiangiogenic activities. Gimatecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I; lethal double-stranded DNA breaks occur when the topoisomerase I-DNA complex is encountered by the DNA replication machinery, DNA replication is disrupted, and the tumor cell undergoes apoptosis. Although the mechanism of its antiangiogenic activity has yet to be full elucidated, this agent may inhibit endothelial cell migration, tumor neovascularization, and the expression of proangiogenic basic fibroblast growth factor (bFGF). Synonyms: ST1481; 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-(O-(1,1-dimethylethyl)oxime), (C(E),4S)-; 7-t-Butoxyiminomethylcamptothecin; (4S)-11-((E)-((1,1-DImethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione; NSC793724. Grades: ≥98%. CAS No. 292618-32-7. Molecular formula: C25H25N3O5. Mole weight: 447.48.
Gimeracil
Gimeracil is an antitumor agent. Gimeracil is a potent inhibitor of dihydropyrimidine dehydrogenase (DPD). Group: Biochemicals. Alternative Names: 5-Chloro-4-hydroxy-2(1H)-pyridinone; 5-Chloro-2,4-dihydroxypyridine; 5-Chloro-4-hydroxy-2-pyridone; Gimestat; CDHP. Grades: Highly Purified. CAS No. 103766-25-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Gimeracil
Gimeracil, a component of an oral fluoropyrimidine derivative S-1, inhibits DNA DSB repair and is a potent inhibitor of DPYD (dihydropyrimidine dehydrogenase, DPD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gimestat. CAS No. 103766-25-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17469.
Gimeracil-13C3
Antitumor agent. A potent inhibitor of dihydropyrimidine dehydrogenase (DPD). Group: Biochemicals. Alternative Names: 5-Chloro-4-hydroxy-2(1H)-pyridinone-13C3; 5-Chloro-2,4-dihydroxypyridine-13C3; 5-Chloro-4-hydroxy-2-pyridone-13C3; Gimestat-13C3; CDHP -13C3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Gimeracil (CDHP)
Cas No. 103766-25-2.
Gimeracil impurity 1
Gimeracil impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149143-68-0. Molecular Formula: C6H3ClN2O2. Mole Weight: 170.55. Catalog: APB149143680.