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| Product | Description | |
|---|---|---|
| Ginsenoside Rg6 | Ginsenoside Rg6. Group: Biochemicals. Grades: Plant Grade. CAS No. 147419-93-0. Pack Sizes: 5mg. Molecular Formula: C42H70O12, Molecular Weight: 767. US Biological Life Sciences. |  Worldwide |
| Ginsenoside Rg6 | Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC 50 of 29.34 μM in HepG2 cells. Ginsenoside Rg6 also exhibits apoptosis -inducing effect. Uses: Scientific research. Group: Natural products. CAS No. 147419-93-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0907. |  |
| Ginsenoside Rh1 | Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β. Uses: Designed for use in research and industrial production. Additional or Alternative Names: β-D-Glucopyranoside, (3β,6α,12β)-3,12,20-trihydroxydammar-24-en-6-yl. Product Category: Inhibitors. Appearance: Powder. CAS No. 63223-86-9. Molecular formula: C36H62O9. Mole weight: 638.88. Purity: 0.98. IUPACName: (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol. Canonical SMILES: CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)O)C)O)C. Density: 1.23 g/ml. Product ID: ACM63223869. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ginsenoside Rb1. |  |
| Ginsenoside Rh1 | Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ , TNF-α , IL-6 , and IL-1&beta. Uses: Scientific research. Group: Natural products. Alternative Names: Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1. CAS No. 63223-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0604. | |
| Ginsenoside Rh1 | Ginsenoside Rh1. Group: Biochemicals. CAS No. 63223-86-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh1 (20(s)-Ginsenoside Rh1) | Ginsenoside Rh1 (20(s)-Ginsenoside Rh1). Group: Biochemicals. Alternative Names: Sanchinoside B2. Grades: Plant Grade. CAS No. 63223-86-9. Pack Sizes: 20mg. Molecular Formula: C36H62O9, Molecular Weight: 638.871999999999. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh2 | Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner. Uses: Scientific research. Group: Natural products. Alternative Names: 20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2. CAS No. 78214-33-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0605. | |
| Ginsenoside Rh2, 20(R)- | Ginsenoside Rh2, 20(R)-. Group: Biochemicals. CAS No. 112246-15-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh2, 20(S)- | Ginsenoside Rh2, 20(S)-. Group: Biochemicals. CAS No. 78214-33-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh2 (20(s)-Ginsenoside Rh2) | Ginsenoside Rh2 (20(s)-Ginsenoside Rh2). Group: Biochemicals. Grades: Plant Grade. CAS No. 78214-33-2. Pack Sizes: 20mg. Molecular Formula: C36H62O8, Molecular Weight: 622.87. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh3 | Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 treatment in human retinal cells induces Nrf2 activation. Uses: Scientific research. Group: Natural products. CAS No. 105558-26-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0606. | |
| Ginsenoside Rh3 | Ginsenoside Rh3. Group: Biochemicals. Grades: Plant Grade. CAS No. 105558-26-7. Pack Sizes: 10mg. Molecular Formula: C36H60O7, Molecular Weight: 604.86. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh3 | Ginsenoside Rh3 is isolated from red ginseng and metabolized from ginsenoside Rg5. It can be anti-inflammatory. Uses: Ginsenoside rh3 is isolated from red ginseng and could be used as an anti-inflammatory agent. Synonyms: [(20Z)-12β-Hydroxy-5α-dammara-20(22),24-dien-3β-yl]β-D-glucopyranoside; (3β, 12β,20Z)-12-Hydroxydammara-20(22),24-dien-3-yl-β-D-glucopyranoside. Grades: >98%. CAS No. 105558-26-7. Molecular formula: C36H60O7. Mole weight: 604.86. |  |
| Ginsenoside Rh4 | Ginsenoside Rh4 is a saponin isolated from the roots of Panax notoginseng (Burk.) F. H. Chen. Ginsenoside Rh4 inhibits Wnt/β-Catenin, JAK2/STAT3, TGF-β/Smad2/3 and other signaling pathways. It is used as an adjuvant with low or non-haemolytic effect. Uses: Antitumour. Synonyms: Ginsenoside Rh(4). Grades: >98%. CAS No. 174721-08-5. Molecular formula: C36H60O8. Mole weight: 620.87. | |
| Ginsenoside Rh4 | Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Ginsenoside Rh4 activates Bax , caspase 3 , caspase 8 , and caspase 9. Ginsenoside Rh4 also induces autophagy. Uses: Scientific research. Group: Natural products. CAS No. 174721-08-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0905. | |
| Ginsenoside RH4 | Ginsenoside RH4. Group: Biochemicals. Grades: Plant Grade. CAS No. 174721-08-5. Pack Sizes: 10mg. Molecular Formula: C36H60O8, Molecular Weight: 620.86. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rh7 | Ginsenoside Rh7 is a new dammarane-type triterpene saponins from the Leaves of Panax ginseng. Panax ginseng is an ancient and famous herbal drug in traditional chinese medicines. Bioactive saponins from natural medicines, a number of dammarane-type triterpene oligoglycosides were found to have anti-cancer, anti-arrhythmia and inhibitory effects on reducing sideeffects of steroid hormones. Synonyms: β-D-Glucopyranoside, (3β,?7β,?12β)?-3,?7,?12-trihydroxydammara-5,?24-dien-20-yl; (3β,7β,12β)-3,7,12-Trihydroxydammara-5,24-dien-20-yl β-D-glucopyranoside. Grades: > 98%. CAS No. 343780-68-7. Molecular formula: C36H60O9. Mole weight: 636.86. | |
| Ginsenoside Rh8 | Ginsenoside Rh8 is a saponin composition of roots of Panax ginseng. Ginsenoside-Rh8 was also obtained as a white powder. Ginsenosides are the primary bioactive components of Asian ginseng and more than 30 ginsenosides were reported from ginseng so far. Ginsenosides Rbl, Rb2, Rc, Rd, Rgl, Rg2, and Re are major constituents of white and red ginsengs, while ginsenosides Rg3, Rgs, and Rg6 are known to be unique constituents of red ginseng. Synonyms: Dammar-24-en-12-one, 20-(β-D-glucopyranosyloxy)-3,6-dihydroxy-, (3β,?6α)-; (3β,6α)-20-(β-D-Glucopyranosyloxy)-3,6-dihydroxydammar-24-en-12-one. Grades: > 98%. CAS No. 343780-69-8. Molecular formula: C36H60O9. Mole weight: 636.86. | |
| Ginsenoside Rk1 | Ginsenoside Rk1 is extracted from the root of Panax ginseng C.A.Mey. It might be a promising compound to induce apoptosis through both extrinsic and intrinsic pathways in SK-MEL-2 cells. It inhibited the undesirable apoptosis of human endothelial cells, which are induced by a vascular injury. Synonyms: (3β, 12β)-12-Hydroxydammara-20,24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside. Grades: >98%. CAS No. 494753-69-4. Molecular formula: C42H70O12. Mole weight: 767.00. | |
| Ginsenoside Rk1 | Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures [1]. Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB [2]. Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis [1]. Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species ( ROS ) generation and blocking PI3K/Akt pathway [3]. Uses: Scientific research. Group: Natural products. CAS No. 494753-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N2515. | |
| Ginsenoside RK1 | Ginsenoside RK1. Group: Biochemicals. Grades: Plant Grade. CAS No. 494753-69-4. Pack Sizes: 5mg. Molecular Formula: C42H70O12, Molecular Weight: 767. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rk1 (Rk1:Rz1=5:2) | Ginsenoside Rk1 (Rk1:Rz1=5:2). Group: Biochemicals. CAS No. 494753-69-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ginsenoside Rk2 | Ginsenoside Rk2 is a new dammarane glycosides isolated from the processed ginseng. Ginseng (Panax ginseng C. A. Meyer, Araliaceae) is one of the most popular herbal medicines in the Orient. The most well known chemical constituent of ginseng is ginsenoside, which is a dammarane glycoside. More than 30 ginsenosides were reported from ginseng so far. Synonyms: (3β,12β)-12-Hydroxydammara-20,24-dien-3-yl β-D-glucopyranoside; 3β,12β-Dihydroxydammar-20(21),24-diene-3-O-β-D-glucopyranoside; PAN 20. Grades: > 98%. CAS No. 364779-14-6. Molecular formula: C36H60O7. Mole weight: 604.86. | |
| Ginsenoside Rk3 | Ginsenoside Rk3. Group: Biochemicals. Grades: Plant Grade. CAS No. 364779-15-7. Pack Sizes: 5mg. Molecular Formula: C36H60O8, Molecular Weight: 620.86. US Biological Life Sciences. | Worldwide |
| Ginsenoside Ro | Ginsenoside Ro. Group: Biochemicals. Alternative Names: Chikusetsusaponin V; Polysciasaponin P3; Hericiumsaponin S3. Grades: Plant Grade. CAS No. 34367-04-9. Pack Sizes: 20mg. Molecular Formula: C48H76O19, Molecular Weight: 957.105999999999. US Biological Life Sciences. | Worldwide |
| GIP (1-39) | GIP (1-39) is an endogenous truncated form of the incretin hormone GIP. GIP (1-39) has the high potency at stimulating glucose-dependent insulin secretion from rat pancreatic β-cells than GIP. Synonyms: Gastric Inhibitory Polypeptide (1-39). CAS No. 725474-97-5. Molecular formula: C210H316N56O61S. Mole weight: 4633.21. | |
| GIP (human) | GIP (human) is a potent insulinotropic hormone synthesized by duodenal K-cells. It inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. Synonyms: Gastric Inhibitory Polypeptide human; Gastric Inhibitory Polypeptide (human); Gastric Inhibitory Peptide (GIP), human; Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln. Grades: 95%. CAS No. 100040-31-1. Molecular formula: C226H338N60O66S. Mole weight: 4983.58. | |
| GIP, human | GIP, human, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Gastric Inhibitory Peptide (GIP), human. CAS No. 100040-31-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0276. | |
| GIP (mouse) | GIP (mouse) is a gastrointestinal hormone that is expressed in and secreted from the pancreatic islets and promotes insulin secretion [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse). CAS No. 181591-59-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10735. | |
| Girard's Reagent P | Girards reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents. Group: Biochemicals. Alternative Names: 1- (Carboxymethyl) pyridinium Chloride Hydrazide; 1-(2-Hydrazino-2-oxoethyl)pyridinium Chloride; Girard-P Reagent; Girards P Reagent; Pyridinioaceto hydrazide Chloride. Grades: Highly Purified. CAS No. 1126-58-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Girards Reagent T | Girards Reagent T. CAS No: 123-46-6 |  Sarchem Laboratories New Jersey NJ |
| Giredestrant | Giredestrant is an orally active and selective ER antagonist with anti-tumor activity. Synonyms: GDC-9545. Grades: ≥98% by HPLC. CAS No. 1953133-47-5. Molecular formula: C27H31F5N4O. Mole weight: 522.6. | |
| Giredestrant | Giredestrant (GDC-9545), a non-steroidal estrogen receptor (ER) ligand, is an orally active and selective ER antagonist. Giredestrant potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-9545; RG6171. CAS No. 1953133-47-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109176. | |
| Girentuximab | Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX) , a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: G250; cG250. CAS No. 916138-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99023. | |
| Girentuximab | Girentuximab is a chimeric monoclonal antibody that binds to carbonic anhydrase IX (CAIX), a cell-surface glycoprotein expressed on clear-cell RCC but not on normal kidney cells. Synonyms: G250; cG250. CAS No. 916138-87-9. | |
| girinimbine | girinimbine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,11-Dihydro-3,3,5-trimethylpyrano[3,2-a]carbazole. CAS No. 23095-44-5. Molecular formula: C18H17NO. Mole weight: 263.3. Purity: 95%+. Product ID: ACM23095445. Alfa Chemistry ISO 9001:2015 Certified. | |
| Giripladib | Giripladib is a Phospholipase A2 inhibitor. Treatment with Giripladib attenuated radiation induced increases of phospho-ERK and phospho-Akt in endothelial cells. Giripladib in combination with irradiation significantly reduced migration and proliferation in endothelial cells and induced cell death and attenuated invasion by tumor cells. Uses: Antitumor. Synonyms: PLA-695; PLA 695; PLA695; Giripladib; 4-[3-[5-Chloro-1- (diphenylmethyl) -2-[2-[[[[2- (trifluoromethyl) phenyl]methyl]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]benzoic Acid; 4- (3-[5-Chloro-1- (diphenylmethyl) -2-[2- ( ( (2- (trifluoromethyl) benzyl) sulfonyl) amino) ethyl]-1H-indole-3-yl]propyl) benzoic Acid; PLA 695. Grades: 98%. CAS No. 865200-20-0. Molecular formula: C41H36ClF3N2O4S. Mole weight: 745.25. | |
| Giripladib | Giripladib inhibits cytosolic phospholipase A2 (cPLA2) which in turn radiosensitizes tumors in lung cancer animal models. Group: Biochemicals. Grades: Highly Purified. CAS No. 865200-20-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C41H36ClF3N2O4S, Molecular Weight: 745.25. US Biological Life Sciences. | Worldwide |
| GIRK Activator, ML297 (1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea, N-(3,4-Difluorophenyl)-N?-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea, CID 56642816, VU0456810) | A blood-brain barrier-permeable, non-toxic phenyl-pyrazolylurea compound that acts as a direct, potent, fast, and reversible activator of GIRK1 (G-protein activated inward-rectifying K+ channel containing subunit 1) containing channels (EC50 = 162, 914, and 887nM in Thallium influx assay for GIRK1/2, GIRK1/3, and GIRK1/4 expressed in HEK-293 cell lines). Its action does not require the presence of an activated Gi GPCR. Shown to be inactive towards GIRK2, GIRK2/3, Kir2.1, KV7.4 and GABAA, and weakly active against a panel of 61 other receptors, ion channels, enzymes, transporters, and proteins even at higher concentration (~10uM). Exhibits desirable pharmacokinetic properties with good solubility (17.5uM), predicted hepatic clearance (88 ml/min/kg), and Tmax of 640nM and 130nM in plasma and brain, respectively. Shown to reduce locomotor function and seizure frequency in electroshock- and chemically-induced murine epilepsy models (60mg/kg, i.p). Group: Biochemicals. Grades: Highly Purified. CAS No. 1443246-62-5. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O. US Biological Life Sciences. | Worldwide |
| Girolline | It is produced by the strain of Pseudaxinyssa cantharella. It can inhibit protein biosynthesis and has anti-tumor effect. Synonyms: Giracodazole; Girodazole; Giracodazolum; (alphaS)-2-Amino-alpha-((1S)-2-amino-1-chloroethyl)imidazole-4-methanol; (1S,2S)-1-(2-Amino-5-imidazolyl)-2-chloro-3-amino-1-propanol. Grades: 95%. CAS No. 110883-46-0. Molecular formula: C6H11ClN4O. Mole weight: 190.63. | |
| Gisadenafil | Gisadenafi is a potent PDE5 inhibitor (IC50 = 1.23 nM). Uses: A potent pde5 inhibitor. Synonyms: UK-369003; UK-369,003; 1-{6-ethoxy-5-[3-ethyl-6,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridylsulfonyl}-4-ethylpiperazine. Grades: ≥98%. CAS No. 334826-98-1. Molecular formula: C23H33N7O5S. Mole weight: 519.62. | |
| Gisadenafil besylate | Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor with an IC 50 of 3.6 nM and prevents degradation of cyclic guanosine monophosphate (cGMP) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 369003-26. CAS No. 334827-98-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108619. | |
| Gisadenafil besylate | Gisadenafil besylate is a potent PDE5 inhibitor (IC50 = 1.23 nM) with >100-fold selectivity for PDE5 over PDE6. Gisadenafil besylate inhibits the breakdown of cyclic phosphodiester secondary messenger molecules. Synonyms: UK 369003; UK369003; UK-369003; 5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one benzenesulfonate. Grades: ≥99% by HPLC. CAS No. 334827-98-4. Molecular formula: C23H33N7O5S.C6H6O3S. Mole weight: 677.79. | |
| Gisadenafil Besylate | Gisadenafil Besylate. Group: Biochemicals. Alternative Names: 5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one Benzenesulfonate; 1-[[6-Ethoxy-5-[3-ethyl-4,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridinyl]sulfonyl]-4-ethylpiperazine Monobenzenesulfonate; UK 369003-26. Grades: Highly Purified. CAS No. 334827-98-4. Pack Sizes: 10mg. Molecular Formula: C29H39N7O8S2, Molecular Weight: 677.79. US Biological Life Sciences. | Worldwide |
| GIT 27 | GIT 27 is an orally active immunomodulatory agent. It inhibits TNF-α secretion via interference of macrophage TLR4 and TLR 2/6 signaling pathway. Synonyms: 5-Dihydro-3-phenyl-5-isoxazoleacetic acid; (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid; 3-phenyl-4,5-dihydro-5-isoxazole acetic acid; VGX-1027; VGX 1027; VGX1027; GIT 27; GIT-27; GIT27. CAS No. 6501-72-0. Molecular formula: C11H11NO3. Mole weight: 205.21. | |
| GIT 27 | GIT 27. Group: Biochemicals. Grades: Purified. CAS No. 6501-72-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Gitogenin | Gitogenin. Group: Biochemicals. Alternative Names: (2alpha,3 β,5alpha,25R)-Spirostan-2,3-diol; Digine. Grades: Plant Grade. CAS No. 511-96-6. Pack Sizes: 20mg. Molecular Formula: C27H44O4, Molecular Weight: 432.636. US Biological Life Sciences. | Worldwide |
| Gitoxin | Gitoxin, a Na + /K + -ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably [1]. Uses: Scientific research. Group: Natural products. CAS No. 4562-36-1. Pack Sizes: 5 mg. Product ID: HY-136933. | |
| Gitoxin | Gitoxin. Group: Biochemicals. Alternative Names: Gitoxigenin 3-O-tridigitoxoside; Anhydrogitalin. Grades: Highly Purified. CAS No. 4562-36-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C41H64O14. US Biological Life Sciences. | Worldwide |
| Givescone ® | Givescone ®. CAS No. 57934-97-1. Kosher: Y. VIGON Item # 500893. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, rose carboxylate. |  America & Internationally |
| Givinostat | Givinostat (ITF-2357) is a HDAC inhibitor with an IC 50 of 198 and 157 nM for HDAC1 and HDAC3 , respectively. Givinostat can be used for Duchenne muscular dystrophy (DMD) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITF-2357. CAS No. 497833-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14842. | |
| Givinostat | Givinostat (INN) or gavinostat, aslo known as ITF2357, is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride. Givinostat is in numerous phase II clinical trials (including for relapsed leukemias and myelomas), and has been granted orphan drug designation in the European Union for the treatment of systemic juvenile idiopathic arthritis and polycythaemia vera. ITF2357 was discovered at Italfarmaco of Milan, Italy. It was patented in 1997 and first described in the scientific literature in 2005. Synonyms: Givinostat; gavinostat; ITF-2357; ITF 2357; ITF2357. CAS No. 497833-27-9. Molecular formula: C24H27N3O4. Mole weight: 421.497. | |
| Givinostat HCl | Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride. Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis.ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro. ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ITF2357; ITF-2357; ITF 2357; ITF2357 HCl; ITF2357 hydrochloride; Givinostat HCl. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 199657-29-9. Molecular formula: C24H28ClN3O4. Mole weight: 457.96. Purity: >98%. IUPACName: (6-((diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride. Canonical SMILES: O=C(OCC1=CC=C2C=C(CN(CC)CC)C=CC2=C1)NC3=CC=C(C(NO)=O)C=C3.[H]Cl. Product ID: ACM199657299. Alfa Chemistry ISO 9001:2015 Certified. Categories: Givinostat hydrochloride. | |
| Givinostat hydrochloride | Givinostat hydrochloride is the hydrochloride salt form of Givinostat. Givinostat, also called as GVS or ITF2357, a potent HDAC inhibitor for Maize HD2 (IC50= 10 nM), HD1-B (IC50= 7.5 nM nM) and HD1-A (IC50= 16 nM), has antiproliferative and proapoptotic. Uses: Histone deacetylase inhibitors. Synonyms: (6-((diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride; ITF2357; ITF-2357; ITF 2357; ITF2357 HCl; ITF2357 hydrochloride; Givinostat HCl gavinostat. CAS No. 199657-29-9. Molecular formula: C24H28ClN3O4. Mole weight: 457.95. | |
| Givinostat hydrochloride | Givinostat (ITF-2357) hydrochloride is a HDAC inhibitor with an IC 50 of 198 and 157 nM for HDAC1 and HDAC3 , respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITF-2357 hydrochloride. CAS No. 199657-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14842A. | |
| Givinostat hydrochloride monohydrate | Givinostat, also known as ITF2357, is an orally active HDAC inhibitor (IC50= 198 and 157 nM for HDAC1 and HDAC3, respectively), with potential anti-inflammatory, anti-angiogenic, and antineoplastic properties. Uses: Histone deacetylase inhibitors. Synonyms: [6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate; hydrate; hydrochloride; givinostat hydrochloride; ITF 2357; ITF2357; ITF-2357; ITF2357 HCl; ITF2357 hydrochloride. CAS No. 732302-99-7. Molecular formula: C24H27N3O4.HCl.H2O. Mole weight: 475.97. | |
| Givinostat hydrochloride monohydrate | Givinostat hydrochloride monohydrate (ITF-2357 hydrochloride monohydrate) is a HDAC inhibitor with an IC 50 of 198 and 157 nM for HDAC1 and HDAC3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITF-2357 hydrochloride monohydrate. CAS No. 732302-99-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14842B. | |
| Givinostat(itf2357) | Givinostat(itf2357). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ITF2357;ITF2357 (Givinostat);N-[4-[(Hydroxyamino)carbonyl]phenyl]carbamic acid [6-[(diethylamino)methyl]-2-naphthalenyl]methyl ester hydrochloride hydrate;(6-((diethylamino)methyl)naphthalen-2-yl)methyl 4-(hydroxycarbamoyl)phenylcarbamate hydrochloride hydrate. Product Category: Heterocyclic Organic Compound. CAS No. 732302-99-7. Molecular formula: C24H30ClN3O5. Mole weight: 475.9651. Product ID: ACM732302997. Alfa Chemistry ISO 9001:2015 Certified. | |
| Givosiran | Cas No. 1639325-43-1. | |
| GJ103 | GJ103 Inhibitor. Uses: Scientific use. Product Category: T4251. CAS No. 1459687-96-7. |  |
| GJ-103 free acid | GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GJ-103 free acid; GJ103; GJ 103; GJ-103. Product Category: Others. Appearance: Solid powder. CAS No. 1459687-89-8. Molecular formula: C16H14N4O3S. Mole weight: 342.37. Purity: >98%. IUPACName: 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid. Canonical SMILES: O=C(O)CSC1=NN=C(C2=NC=CC=C2)N1C3=CC=CC(OC)=C3. Product ID: ACM1459687898. Alfa Chemistry ISO 9001:2015 Certified. | |
| GJ-103 sodium | GJ103 sodium salt is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GJ-103 sodium. Product Category: Others. Appearance: Solid powder. CAS No. 1459687-96-7. Molecular formula: C16H13N4NaO3S. Mole weight: 364.35. Purity: >98%. IUPACName: sodium 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate. Canonical SMILES: O=C(O[Na])CSC1=NN=C(C2=NC=CC=C2)N1C3=CC=CC(OC)=C3. Product ID: ACM1459687967. Alfa Chemistry ISO 9001:2015 Certified. | |
| GK187 | GK187 is a highly potent and selective inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). Synonyms: 1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)-3-heptanone. Grades: ≥95%. CAS No. 1071001-50-7. Molecular formula: C14H15F5O2. Mole weight: 310.26. | |
| GK921 | GK921 Inhibitor. Uses: Scientific use. Product Category: T3968. CAS No. 1025015-40-0. | |
| GK921 | GK921 is a transglutaminase 2 (TGase 2) inhibitor with average GI50 of 0.9 μM in cancer cell lines. Synonyms: GK921; GK-921; GK 921. Grades: >98%. CAS No. 1025015-40-0. Molecular formula: C21H20N4O. Mole weight: 344.41. | |
| GKA 50 | GKA 50 is a potent glucokinase activator (EC50 = 33 nM). It causes a decrease in plasma glucose levels in diabetic rats and an increase of insulin release from mouse islets of Langerhans. GKA 50 was shown to promote proliferation and prevent apoptosis in rat pancreatic insulinoma-1 beta cell. Synonyms: GKA 50; GKA50; GKA-50; 6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino-3-pyridinecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 851884-87-2. Molecular formula: C26H28N2O6. Mole weight: 464.51. | |
| GKA 50 | GKA 50. Group: Biochemicals. Grades: Purified. CAS No. 851884-87-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GKT137831 | GKT137831 attenuates hypoxia-induced H(2)O(2) release, cell proliferation, and TGF-β1 expression and blunted reductions in PPARγ in HPAECs and HPASMCs. Synonyms: GKT137831; GKT-137831; GKT 137831; GTK831; GTK-831; GTK 831. Grades: >98%. CAS No. 1218942-37-0. Molecular formula: C21H19ClN4O2. Mole weight: 394.85. | |
| GL0388 | GL0388 is a Bax activator that results in Bax insertion into mitochondrial membrane. GL0388 shows antiproliferative activities against various cancer cells, with IC 50 s of 0.299-1.57 μM. GL0388 activates Bax and induce Bax-mediated apoptosis. GL0388 suppresses breast cancer xenograft tumor growth in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2886772-68-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132173. | |
| GL3 | GL3, the major component of O. fragrans seeds, is a derivative based on both phenylethanoid and methyloleoside [1]. Uses: Scientific research. Group: Natural products. CAS No. 60037-39-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6873. | |
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