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It is a specific fluorogenic substrate for dipeptidyl peptidase II (DPP II). Synonyms: Lys-Ala 4-methoxy-beta-naphthylamide dihydrochloride. Grade: 95%. CAS No. 118357-26-9. Molecular formula: C20H30Cl2N4O3. Mole weight: 445.38.
H-Lys-ala-ala-oh
H-Lys-ala-ala-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-lysyl-L-alanyl-L-alanine; Lys-Ala-Ala. Product Category: Heterocyclic Organic Compound. CAS No. 34385-54-1. Molecular formula: C12H24N4O4. Mole weight: 288.343. Purity: 0.96. IUPACName: H-Lys-Ala-Ala-OH. Product ID: ACM34385541. Alfa Chemistry ISO 9001:2015 Certified.
H-Lys-Ala-pNA 2HCl, a chromogenic substrate for dipeptidyl aminopeptidase II (DPPII), is cleaved from Aspergillus fumigatus by dipeptidyl peptidase V (DPP V). Synonyms: KA-pNA dihydrochloride; L-Lysyl-N-(4-nitrophenyl)-L-alaninamide dihydrochloride; L-Alaninamide, L-lysyl-N-(4-nitrophenyl)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 390366-87-7. Molecular formula: C15H23N5O4.2HCl. Mole weight: 410.30.
H-Lys-AMC
H-Lys-AMC is a substrate for aminopeptidase b. Synonyms: L-Lysine 7-amido-4-methylcoumarin. CAS No. 92605-76-0. Molecular formula: C16H21N3O3. Mole weight: 303.36.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Lys(Boc)-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: Nepsilon-Boc-L-lysine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
H-Lys(Boc)-OH
H-Lys(Boc)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 2418-95-3. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C11H22N2O4. US Biological Life Sciences.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Lys-ile-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-LYSYL-L-ISOLEUCINE;H-LYS-ILE-OH. CAS No. 20556-13-2. Molecular formula: C12H25N3O3. Mole weight: 259.35. Purity: 0.95. IUPACName: (2S,3S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-methylpentanoic acid. Canonical SMILES: CCC(C)C(C(=O)O)NC(=O)C(CCCCN)N. Product ID: ACM20556132. Alfa Chemistry ISO 9001:2015 Certified. Categories: Lysyl-Isoleucine.
H-Lys(Me)3-OH Chloride
Nε,Nε,Nε-Trimethyllysine hydrochloride is a non-protein amino acid active in the biosynthesis of carnitine. Synonyms: Lys(Me)3-OH Chloride; (S)-5-Amino-5-carboxy-N,N,N-trimethylpentan-1-aminium chloride; Nε,Nε,Nε-Trimethyllysine hydrochloride. CAS No. 55528-53-5. Molecular formula: C9H21ClN2O2. Mole weight: 224.73.
H-Lys(Mtt)-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Lys(Mtt)-Trt(2-Cl)-Resin; N-ε-(4-Methyltrityl)-L-lysine 2-chlorotrityl resin.
H-Lys-Phe-Glu-Arg-Gln-OH
H-Lys-Phe-Glu-Arg-Gln-OH plays a broad role in targeting protein-enhanced degradation. Synonyms: L-Glutamine, L-lysyl-L-phenylalanyl-L-α-glutamyl-L-arginyl-; H-KFERQ-OH; L-lysyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-glutamine. Grade: ≥95%. CAS No. 115084-19-0. Molecular formula: C31H50N10O9. Mole weight: 706.79.
H-Lys-Phe-OH. HCl
H-Lys-Phe-OH exerts a remarkable ACE- and renin-inhibitory activity. Synonyms: L-Lysyl-L-phenylalanine hydrochloride. CAS No. 4078-58-4. Molecular formula: C15H24ClN3O3. Mole weight: 329.82.
H-Lys-Pro-OH
H-Lys-Pro-OH has the potential as a very promising healing agent in ulcer therapy. Synonyms: Lysylproline; Lys-pro; Lysyl-Proline; L-lysyl-L-proline; KP dipeptide; Lysine Proline dipeptide; L-Proline, L-lysyl-. CAS No. 52766-27-5. Molecular formula: C11H21N3O3. Mole weight: 243.30.
H-Lys(retro-glu-H)-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-LYS(RETRO-GLU-H)-OH. Product Category: Heterocyclic Organic Compound. CAS No. 5891-46-3. Molecular formula: C11H21N3O5. Product ID: ACM5891463. Alfa Chemistry ISO 9001:2015 Certified.
H-Lys-thr-tyr-oh
H-Lys-thr-tyr-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-LYS-THR-TYR-OH. Product Category: Heterocyclic Organic Compound. CAS No. 108191-44-2. Molecular formula: C19H30N4O6. Mole weight: 410.46. Product ID: ACM108191442. Alfa Chemistry ISO 9001:2015 Certified.
H-Lys-Trp-Lys-OH
H-Lys-Trp-Lys-OH is the positively charged oligopeptide. It displays antibacterial and antiviral activities. Synonyms: Lysyl-tryptophyl-alpha-lysine; N2-(N-L-Lysyl-L-tryptophyl)-L-lysine; L-Lys-L-Trp-L-Lys-OH. Grade: ≥98%. CAS No. 38579-27-0. Molecular formula: C23H36N6O4. Mole weight: 460.57.
H-Lys-Tyr-Lys-OH can induce nicks at apurinic/apyrimidinic sites in circular DNA. Synonyms: Lysyl-tyrosyl-lysine; L-Lysine, N2-(N-L-lysyl-L-tyrosyl)-; (S)-6-amino-2-((S)-2-((S)-2,6-diaminohexanamido)-3-(4-hydroxyphenyl)propanamido)hexanoic acid. Grade: ≥97%. CAS No. 35193-18-1. Molecular formula: C21H35N5O5. Mole weight: 437.53.
H-Lys-tyr-oh
H-Lys-tyr-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-LYSYL-L-TYROSINE;H-LYS-TYR-OH;L-Lys-L-Tyr-OH;Lys-Tyr-OH;N-L-Lysyl-L-tyrosine. Product Category: Heterocyclic Organic Compound. CAS No. 35978-98-4. Molecular formula: C15H23N3O4. Mole weight: 309.36. Product ID: ACM35978984. Alfa Chemistry ISO 9001:2015 Certified.
H-LYS-TYR-OH
H-LYS-TYR-OH. Synonyms: Lys-Tyr; L-lysyl-L-tyrosine; Lysyltyrosine; KY dipeptide; Lysine Tyrosine dipeptide. CAS No. 35978-98-4. Molecular formula: C15H23N3O4. Mole weight: 309.36.
H-Lys(Z)-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 1155-64-2. Pack Sizes: 100 g; 500 g. Product ID: HY-W007750.
H-Lys(Z)-OMe.HCl
H-Lys(Z)-OMe.HCl is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 27894-50-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W008182.
HM03
HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500565-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125974.
HM03 trihydrochloride
HM03 trihydrochloride is a potent and selective inhibitor of HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) with anticancer activity. Synonyms: 4-[(6-Chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]phenol trihydrochloride; Phenol, 4-[(6-chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-, hydrochloride (1:3). Grade: ≥95%. CAS No. 1082532-95-3. Molecular formula: C26H30Cl4N4O2. Mole weight: 572.35.
HM30181
HM30181 is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). HM30181 is currently under Phase I HM30181 is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). HM30181 is currently under Phase I trials. HM30181 was well tolerated after oral administration within the dose range evaluated, with the exception of the repeated administration of 360 mg, for which gastrointestinal disorders were frequently reported. The systemic exposure of HM30181 was relatively low, and dose proportional properties of HM30181 were not observed.trials. HM30181 was well tolerated after oral administration within the dose range evaluated, with the exception of the repeated administration of 360 mg, for which gastrointestinal disorders were frequently reported. The systemic exposure of HM30181 was relatively low, and dose proportional properties of HM30181 were not observed. Synonyms: 4H-1-B
HM-30181 hydrochloride
HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 hydrochloride; HM 30181 hydrochloride; HM30181 hydrochloride; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide hydrochloride. Grade: 98%. CAS No. 849675-88-3. Molecular formula: C38H37ClN6O7. Mole weight: 725.20.
HM-30181 mesylate
HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 mesylate; HM 30181 mesylate; HM30181 mesylate; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide methanesulfonate; 849675-88-3 (HM30181 HCl salt); 49675-66-7 (HM30181 Free base). Grade: 98%. CAS No. 849675-87-2. Molecular formula: C39H40N6O10S. Mole weight: 784.84.
HM-30181 mesylate monohydrate
HM-30181 mesylate monohydrate is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Synonyms: Encequidar mesylate monohydrate; HM-30181 methanesulfonate monohydrate; HM30181 mesylate monohydrate; 4H-1-Benzopyran-2-carboxamide, N-(2-(2-(4-(2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-, methanesulfonate, hydrate (1:1:1); FM0F74; HM 30181A; N-[2-(2-{4-[2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]phenyl}-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl]-4-oxo-4H-1-benzopyran-2-carboxamide methanesulfonate hydrate (1:1:1); N-[2-[2-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-2H-tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxo-4H-1-benzopyran-2-carboxamide methanesulfonate hydrate (1:1:1); TCA.MSA. Grade: ≥95%. CAS No. 2097125-58-9. Molecular formula: C38H36N6O7.CH4O3S.H2O. Mole weight: 802.85.
HM43239
HM43239 is an orally active and selective inhibitor of FLT3. HM43239 directly inhibits the kinase activity of FLT3 as a reversible Type I inhibitor and effectively modulates downstream p-STAT5 and p-ERK. Synonyms: HM-43239; HM 43239. CAS No. 2569527-64-4. Molecular formula: C29H33ClN6. Mole weight: 501.07.
HM43239
HM43239 is an orally active small molecule inhibitor of FLT3 that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. HM43239 directly inhibits the kinase activity of FLT3 as a reversible Type I inhibitor and effectively modulates downstream p-STAT5 and p-ERK. HM43239 also demonstrated inhibition of SYK, JAK1/2 and TAK1, known to be involved in tumor cell proliferation and/or differentiation HM43239 monotherapy induced dose-dependent regression of tumor growth in FLT3 wild-type and FLT3 mutated leukemia cancer cell line. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HM43239; HM-43239; HM 43239. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2569527-64-4. Molecular formula: C29H33ClN6. Mole weight: 501.08. Purity: >98%. IUPACName: rel-5-Chloro-N-[3-cyclopropyl-5-[[(3R,5S)-3,5-dimethyl-1-piperazinyl]methyl]phenyl]-4-(6-methyl-1H-indol-3-yl)-2-pyrimidinamine. Canonical SMILES: CC1=CC2=C(C=C1)C(C3=NC(NC4=CC(CN5C[C@@H](C)N[C@@H](C)C5)=CC(C6CC6)=C4)=NC=C3Cl)=CN2. Product ID: ACM2569527644. Alfa Chemistry ISO 9001:2015 Certified. Categories: tuspetinib.
HM 50316
HM 50316 is a high affinity fatty-acid binding protein 4 (FABP4) inhibitor (Ki < 1 nM) that selectively inhibits FABP4 over FABP3. It inhibits LPS-induced activation of murine macrophages in vitro. HM 50316 may be beneficial for the treatment of atherosclerosis, type 2 diabetes and other inflammatory and metabolic related diseases. Synonyms: HM-50316; HM 50316; HM50316. 2-[[2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methylpropanoic acid. Grade: ≥98% by HPLC. CAS No. 1310361-52-4. Molecular formula: C29H23ClN2O3S. Mole weight: 515.02.
HMBA AM resin. Synonyms: 4-Hydroxymethylbenzoyl AM resin; Hydroxymethylbenzoic acid aminomethyl resin.
HMBA AM resin
HMBA AM resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
HMBR
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525-539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1287651-36-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1416.
HMB-Val-Ser-Leu-VE
HMB-val-ser-leu-VE is a potent and selective inhibitor of the trypsin-like activity of the 20S proteasome. Synonyms: Ethyl (E,4S)-4-[[(2S)-3-hydroxy-2-[[(2S)-2-[(3-hydroxy-2-methylbenzoyl)amino]-3-methylbutanoyl]amino]propanoyl]amino]-6-methylhept-2-enoate. Grade: ≥98%. CAS No. 862891-04-1. Molecular formula: C26H39N3O7. Mole weight: 505.6.
HMDP
HMDP. Group: Biochemicals. Grades: Highly Purified. CAS No. 14255-61-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: CH4Na2O7P2. US Biological Life Sciences.
Worldwide
HmdSL-37
HmdSL-37 is an antimicrobial peptide produced by Hylobates sp. (Gibbon, Hylobates moloch). It has antibacterial activity. Synonyms: Antibacterial protein LL-37; Ser-Leu-Gly-Asn-Phe-Phe-Arg-Lys-Ala-Arg-Lys-Lys-Ile-Gly-Glu-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Gln-His-Leu-Ile-Pro-Arg-Thr-Glu-Ala. Grade: ≥96%.
H-Met-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Met-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: L-Methionine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
H-Met-Ala-OH
H-Met-Ala-OH. Synonyms: Methionylalanine; MA dipeptide; Methionine Alanine dipeptide; (S)-2-((S)-2-Amino-4-(methylthio)butanamido)Propanoic acid. CAS No. 3061-96-9. Molecular formula: C8H16N2O3S. Mole weight: 220.29.
H-Met-amc
H-Met-amc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Butanamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-(methylthio)-, (S)-. Product Category: Heterocyclic Organic Compound. CAS No. 94367-34-7. Molecular formula: C15H18N2O3S. Mole weight: 306.39. Purity: 0.96. IUPACName: Butanamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-(methylt. Density: 1.299±0.06 g/cm³ (20 °C, 760 mmHg). Product ID: ACM94367347. Alfa Chemistry ISO 9001:2015 Certified.
H-Met-Arg-Phe-Ala-OH is a substrate for dipeptidyl peptidase III from human erythrocytes and for snapalysin. It has been shown to be a competitive inhibitor of an enkephalin-generating endopeptidase isolated from rat brain. Synonyms: L-Methionyl-L-arginyl-L-phenylalanyl-L-alanine. CAS No. 67368-29-0. Molecular formula: C23H37N7O5S. Mole weight: 523.65.
H-MET-ASN-OH. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MET-ASN PEPTIDE;L-METHIONYL-L-ASPARAGINE;H-MET-ASN-OH;H2N-MN-OH;MET-ASN CRYSTALLINE;Met-Asn. Product Category: Heterocyclic Organic Compound. CAS No. 36261-61-7. Molecular formula: C9H17N3O4S. Mole weight: 263.31. Product ID: ACM36261617. Alfa Chemistry ISO 9001:2015 Certified.
H-Met-ser-arg-pro-ala-cys-pro-asn-asp-lys-tyr-glu-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4-N,N'-DIMETHYLANILINO)-PENTAFLUOROSULFONAMIDE;H-MET-SER-ARG-PRO-ALA-CYS-PRO-ASN-ASP-LYS-TYR-GLU-OH;MET-SER-ARG-PRO-ALA-CYS-PRO-ASN-ASP-LYS-TYR-GLU;THROMBIN RECEPTOR ANTAGONIST;T1;T113242;PEPTIDE T1;Thrombin Receptor Antagonist (1). Product Category: Heterocyclic Organic Compound. CAS No. 207553-92-2. Molecular formula: C58H91N17O20S2. Mole weight: 1410.58. Product ID: ACM207553922. Alfa Chemistry ISO 9001:2015 Certified.
H-MET-TRP-OH is an incomplete breakdown product of protein digestion or protein catabolism. It is a non-competitive inhibitor of angiotensin-1 converting enzyme (ACE), with an IC50 of 9.8 μM. Synonyms: Methionyltryptophan; L-Methionyl-L-tryptophan; Met-trp; L-Met-L-Trp; N-L-methionyl-L-tryptophan. Grade: 95%. CAS No. 60535-02-6. Molecular formula: C16H21N3O3S. Mole weight: 335.42.