A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
5g Pack Size. Group: Building Blocks, Inorganic Chemicals. Formula: C3F9LaO9S3. CAS No. 52093-26-2. Prepack ID 26600472-5g. Molecular Weight 586.11. See USA prepack pricing.
Lanthanum Yttrium Germanate (LaYGe) is a promising electrolyte material for solid oxide fuel cells (SOFCs) and alternative energy applications. Group: Electrolytes. Alternative Names: Germanium lanthanum yttrium oxide, LaYGe, Yttrium lanthanum germanate. CAS No. 1067877-96-6. Molecular formula: La8Y2Ge6O27. Mole weight: 2156.88. Appearance: White powder. Purity: 99%|99.9%|99.99%|99.999%. Catalog: ACM1067877966-3.
lanthionine
lanthionine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 922-55-4. Molecular Formula: C6H12N2O4S. Mole Weight: 208.23. Catalog: APB922554.
Lanthionine
Lanthionine is a non-proteinogenic natural amino acid, which is an essential component of peptidoglycan found in the cell wall of Fusobacterium species. Synonyms: L-Cysteine, S-[(2R)-2-amino-2-carboxyethyl]-; (2R,2'R)-3,3'-thiobis(2-aminopropanoic acid); L-Cysteine, S-(2-amino-2-carboxyethyl)-, (R)-; Alanine, 3,3'-thiodi-, L-; S-[(2R)-2-Amino-2-carboxyethyl]-L-cysteine; L-Alanine, 3,3'-thiobis-; NSC 83248; Sulfide, bis(2-amino-2-carboxyethyl), [R-(R*,R*)]-; L-Lanthionine. Grades: ≥95%. CAS No. 922-55-4. Molecular formula: C6H12N2O4S. Mole weight: 208.24.
Lantibiotic 97518
Lantibiotic 97518 is an antibacterial peptide isolated from Planomonospora sp. It has activity against gram-negative bacteria. Synonyms: Bacteriocin 97518; Ile-Thr-Ser-Val-Ser-Trp-Cys-Thr-Pro-Gly-Cys-Thr-Ser-Glu-Gly-Gly-Gly-Ser-Gly-Cys-Ser-His-Cys-Cys.
Lantibiotic actagardine
Lantibiotic actagardine is an antibacterial peptide. It has activity against gram-positive bacteria. Synonyms: Ser-Ser-Gly-Trp-Val-Cys-Thr-Leu-Thr-Ile-Glu-Cys-Gly-Thr-Val-Ile-Cys-Ala-Cys. Molecular formula: C81H124N20O24S4. Mole weight: 1890.2.
Lantibiotic carnocin-UI49
Lantibiotic carnocin-UI49 is an antibacterial peptide isolated from Carnobacterium sp. It has activity against gram-positive bacteria. Synonyms: Gly-Ser-Glu-Ile-Gln-Pro-Arg. Grades: 97.3%.
Lantibiotic cinnamycin
Lantibiotic cinnamycin is an antibacterial peptide isolated from Streptoverticillium griseoverticillatum. It has activity against bacteria and viruses. Synonyms: Cys-Arg-Gln-Ser-Cys-Ser-Phe-Gly-Pro-Phe-Thr-Phe-Val-Cys-Asp-Gly-Asn-Thr-Lys. Molecular formula: C89H125N25O25S3. Mole weight: 2041.3.
Lantibiotic epilancin
Lantibiotic epilancin is an antibacterial peptide isolated from Staphylococcus epidermidis. Synonyms: Epilancin K7; Ser-Ala-Ser-Val-Leu-Lys-Thr-Ser-Ile-Lys-Val-Ser-Lys-Lys-Tyr-Cys-Lys-Gly-Val-Thr-Leu-Thr-Cys-Gly-Cys-Asn-Ile-Thr-Gly-Gly-Lys.
Lantibiotic epilancin 15X
Lantibiotic epilancin 15X is an antibacterial peptide isolated from Staphylococcus epidermidis. It has activity against gram-positive bacteria. Synonyms: Ser-Ala-Ser-Ile-Val-Lys-Thr-Thr-Ile-Lys-Ala-Ser-Lys-Lys-Leu-Cys-Arg-Gly-Phe-Thr-Leu-Thr-Cys-Gly-Cys-His-Phe-Thr-Gly-Lys-Lys.
Lantibiotic lacticin 3147 A1
Lantibiotic lacticin 3147 A1 is an antibacterial peptide isolated from Lactococcus lactis subsp. lactis. It has activity against gram-positive bacteria. Synonyms: Cys-Ser-Thr-Asn-Thr-Phe-Ser-Leu-Ser-Asp-Tyr-Trp-Gly-Asn-Asn-Gly-Ala-Trp-Cys-Thr-Leu-Thr-His-Glu-Cys-Met-Ala-Trp-Cys-Lys.
Lantibiotic lacticin 3147 A2
Lantibiotic lacticin 3147 A2 is an antibacterial peptide isolated from Lactococcus lactis subsp. lactis. It has activity against gram-positive bacteria. Synonyms: Thr-Thr-Pro-Ala-Thr-Pro-Ala-Ile-Ser-Ile-Leu-Ser-Ala-Tyr-Ile-Ser-Thr-Asn-Thr-Cys-Pro-Thr-Thr-Lys-Cys-Thr-Arg-Ala-Cys.
Lantibiotic lacticin-481
Lantibiotic lacticin-481 is an antibacterial peptide isolated from Lactococcus lactis subsp. lactis. It has activity against gram-positive bacteria. Synonyms: Lys-Gly-Gly-Ser-Gly-Val-Ile-His-Thr-Ile-Ser-His-Glu-Cys-Asn-Met-Asn-Ser-Trp-Gln-Phe-Val-Phe-Thr-Cys-Cys-Ser. Molecular formula: C127H182N36O35S4. Mole weight: 2901.3.
Lantibiotic lichenicidin A2
Lantibiotic lichenicidin A2 is an antibacterial peptide isolated from Bacillus licheniformis. Synonyms: Thr-Pro-Ala-Thr-Thr-Ser-Ser-Trp-Thr-Cys-Ile-Thr-Ala-Gly-Val-Thr-Val-Ser-Ala-Ser-Leu-Cys-Pro-Thr-Thr-Lys-Cys-Thr-Ser-Arg-Cys.
Lantibiotic lichenicidin VK21 A2
Lantibiotic lichenicidin VK21 A2 is an antibacterial peptide isolated from Bacillus licheniformis. Synonyms: Thr-Thr-Pro-Ala-Thr-Thr-Ser-Ser-Trp-Thr-Cys-Ile-Thr-Ala-Gly-Val-Thr-Val-Ser-Ala-Ser-Leu-Cys-Pro-Thr-Thr-Lys-Cys-Thr-Ser-Arg-Cys.
Lantibiotic Mersacidin
Lantibiotic Mersacidin is an antibacterial peptide isolated from Bacillus sp. It has activity against gram-positive bacteria. Synonyms: Mersacidin. Molecular formula: C80H120N20O21S4. Mole weight: 1826.2.
Lantibiotic michiganin-A
Lantibiotic michiganin-A is an antibacterial peptide isolated from Clavibacter michiganensis subsp. michiganensis. Synonyms: Ser-Ser-Ser-Gly-Trp-Leu-Cys-Thr-Leu-Thr-Ile-Glu-Cys-Gly-Thr-Ile-Ile-Cys-Ala-Cys-Arg. Molecular formula: C92H145N25O26S4. Mole weight: 2145.6.
Lantibiotic mutacin-2
Lantibiotic mutacin-2 is an antibacterial peptide isolated from Streptococcus mutans. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Asn-Arg-Trp-Trp-Gln-Gly-Val-Val-Pro-Thr-Val-Ser-Tyr-Glu-Cys-Arg-Met-Asn-Ser-Trp-Gln-His-Val-Phe-Thr-Cys-Cys.
Lantibiotic mutacin B-Ny266
Lantibiotic mutacin B-Ny266 is an antibacterial peptide isolated from Streptococcus mutans. It has activity against gram-positive bacteria. Synonyms: Phe-Lys-Ser-Trp-Ser-Phe-Cys-Thr-Pro-Gly-Cys-Ala-Lys-Thr-Gly-Ser-Phe-Asn-Ser-Tyr-Cys-Cys.
Lantibiotic nisin-A
Lantibiotic nisin-A is an antibacterial peptide isolated from Lactococcus lactis subsp. lactis (Streptococcus lactis). lactis. It has activity against gram-positive bacteria. Synonyms: Ile-Thr-Ser-Ile-Ser-Leu-Cys-Thr-Pro-Gly-Cys-Lys-Thr-Gly-Ala-Leu-Met-Gly-Cys-Asn-Met-Lys-Thr-Ala-Thr-Cys-His-Cys-Ser-Ile-His-Val-Ser-Lys.
Lantibiotic nisin-U
Lantibiotic nisin-U is an antibacterial peptide isolated from Lactococcus lactis subsp. lactis (Streptococcus lactis). lactis. It has activity against gram-positive bacteria. Synonyms: Ile-Thr-Ser-Lys-Ser-Leu-Cys-Thr-Pro-Gly-Cys-Lys-Thr-Gly-Ile-Leu-Met-Thr-Cys-Pro-Leu-Lys-Thr-Ala-Thr-Cys-Gly-Cys-His-Phe-Gly.
Lantibiotic nisin-Z
Lantibiotic nisin-Z is an antibacterial peptide isolated from Lactococcus lactis subsp. lactis (Streptococcus lactis). lactis. It has activity against gram-positive bacteria. Synonyms: Ile-Thr-Ser-Ile-Ser-Leu-Cys-Thr-Pro-Gly-Cys-Lys-Thr-Gly-Ala-Leu-Met-Gly-Cys-Asn-Met-Lys-Thr-Ala-Thr-Cys-Asn-Cys-Ser-Ile-His-Val-Ser-Lys.
Lantibiotic nukacin
Lantibiotic nukacin is an antibacterial peptide isolated from Staphylococcus hominis. Synonyms: Bacteriocin nukacin; Nukacin KQ-1; Lys-Lys-Ser-Gly-Val-Ile-Pro-Thr-Val-Ser-His-Asp-Cys-His-Met-Asn-Thr-Phe-Gln-Phe-Met-Phe-Thr-Cys-Cys-Ser.
Lantibiotic nukacin precursor
Lantibiotic nukacin precursor is an antibacterial peptide isolated from Staphylococcus warneri. Synonyms: Lys-Lys-Lys-Ser-Gly-Val-Ile-Pro-Thr-Val-Ser-His-Asp-Cys-His-Met-Asn-Ser-Phe-Gln-Phe-Val-Phe-Thr-Cys-Cys-Ser.
Lantibiotic paenibacillin
Lantibiotic paenibacillin is an antibacterial peptide isolated from Paenibacillus polymyxa. It has activity against gram-positive bacteria. Synonyms: Ala-Ser-Ile-Ile-Lys-Thr-Thr-Ile-Lys-Val-Ser-Lys-Ala-Val-Cys-Lys-Thr-Leu-Thr-Cys-Ile-Cys-Thr-Gly-Ser-Cys-Ser-Asn-Cys-Lys.
Lantibiotic Pep5
Lantibiotic Pep5 is an antibacterial peptide isolated from Staphylococcus epidermidis. Synonyms: Thr-Ala-Gly-Pro-Ala-Ile-Arg-Ala-Ser-Val-Lys-Gln-Cys-Gln-Lys-Thr-Leu-Lys-Ala-Thr-Arg-Leu-Phe-Thr-Val-Ser-Cys-Lys-Gly-Lys-Asn-Gly-Cys-Lys. CAS No. 84931-86-2. Molecular formula: C153H258N46O41S6. Mole weight: 3590.4.
Lantibiotic salivaricin-A
Lantibiotic salivaricin-A is an antibacterial peptide isolated from Streptococcus salivarius. Synonyms: SalA; Lys-Arg-Gly-Ser-Gly-Trp-Ile-Ala-Thr-Ile-Thr-Asp-Asp-Cys-Pro-Asn-Ser-Val-Phe-Val-Cys-Cys.
Lantibiotic streptin
Lantibiotic streptin is an antibacterial peptide isolated from Streptococcus pyogenes. It has activity against gram-positive bacteria. Synonyms: Gly-Ser-Arg-Tyr-Leu-Cys-Thr-Pro-Gly-Ser-Cys-Trp-Lys-Leu-Val-Cys-Phe-Thr-Thr-Thr-Val-Lys.
Lantibiotic streptococcin A-FF22
Lantibiotic streptococcin A-FF22 is an antibacterial peptide isolated from Streptococcus pyogenes. Synonyms: Gly-Lys-Asn-Gly-Val-Phe-Lys-Thr-Ile-Ser-His-Glu-Cys-His-Leu-Asn-Thr-Trp-Ala-Phe-Leu-Ala-Thr-Cys-Cys-Ser.
Lantibiotic subtilin
Lantibiotic subtilin is an antibacterial peptide isolated from Bacillus subtilis. Synonyms: Trp-Lys-Ser-Glu-Ser-Leu-Cys-Thr-Pro-Gly-Cys-Val-Thr-Gly-Ala-Leu-Gln-Thr-Cys-Phe-Leu-Gln-Thr-Leu-Thr-Cys-Asn-Cys-Lys-Ile-Ser-Lys. CAS No. 1393-38-0. Molecular formula: C148H227N39O38S5. Mole weight: 3320.94.
L-Antimony potassium tartrate
Heterocyclic Organic Compound. Alternative Names: L-Antimony potassium tartrate. CAS No. 11071-15-1. Molecular formula: C8H4K2O12Sb2. Mole weight: 613.82. Appearance: white crystals. Purity: 0.96. IUPACName: L-Antimony Potassium Tartrate. Catalog: ACM11071151.
LAO Single Crystal Substrate
LAO Single Crystal Substrate. Group: Single crystal substrates. >99.9%.
LAP
LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Lithium phenyl-2,4,6-trimethylbenzoylphosphinate. CAS No. 85073-19-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-44076.
LAP
LAP is a cytocompatible, water soluble, Type I photoinitiator. It is used in the polymerization of hydrogels or other polymeric materials, specifically in the photopolymerization of PEG-diacrylate. It is preferred over irgacure 2959 for biological applications because of its increased polymerization rates with 365 nm light and absorbance at 400 nm, which allows for polymerization with visible light. It enables cell encapsualation at reduced initiator concentration and longer wavelength light, which has been proved to reduce initiator toxicity and increase cell viability. Synonyms: P-Phenyl-P-(2,4,6-trimethylbenzoyl)phosphinic Acid; Phenyl(2,4,6-trimethylbenzoyl)-phosphinic Acid Lithium Salt; Lithium Phenyl-2,4,6-trimethylbenzoylphosphinate; Lithium PTMB phosphinate. Grades: ≥98% by HPLC. CAS No. 85073-19-4. Molecular formula: C16H16LiO3P. Mole weight: 294.21.
L-AP4
L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus. L-AP4 is a synaptic depressant. Synonyms: L-(+)-2-Amino-4-phosphonobutyric acid; (2S)-2-amino-4-phosphonobutanoic acid; L-AP4; L AP4; LAP4. Grades: ≥99% by HPLC. CAS No. 23052-81-5. Molecular formula: C4H10NO5P. Mole weight: 183.1.
L-AP4
L-AP4 (L-APB) is a potent and specific agonist for the group III mGluRs , with EC 50 s of 0.13, 0.29, 1.0, 249 μM for mGlu 4 , mGlu 8 , mGlu 6 and mGlu 7 receptors, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-APB. CAS No. 23052-81-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100781A.
L-AP4
L-AP4. Group: Biochemicals. Grades: Purified. CAS No. 23052-81-5. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
L-AP5
L-AP5 has been found to be an NMDA antagonist as well as a quisqualate-sensitized AP6 site agonist. Synonyms: L-(+)-2-Amino-5-phosphonopentanoic acid. Grades: ≥99% by HPLC. CAS No. 79055-67-7. Molecular formula: C5H12NO5P. Mole weight: 197.13.
L-AP5
L-AP5. Group: Biochemicals. Grades: Purified. CAS No. 79055-67-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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L-AP6
L-AP6 is a selective agonist for 'quis'-sensitized site. Synonyms: L-AP6; L AP6; LAP6; L-(+)-2-Amino-6-phosphonohexanoic acid; 6-Phosphononorleucine. Grades: ≥95% by HPLC. CAS No. 78944-89-5. Molecular formula: C6H14NO5P. Mole weight: 211.15.
L-AP6
L-AP6. Group: Biochemicals. Grades: Purified. CAS No. 78944-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Lapachol
Lapachol is a reagent used in the synthesis of B-Lapachones for use in anti-proliferative tumor studies. Lapachol itself is a powerful antidepressant compound, having the napthoquinone moiety in the substructure. Group: Biochemicals. Alternative Names: 2-Hydroxy-3-(3-methyl-2-buten-1-yl)-1,4-Naphthalenedione; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-Naphthoquinone; Lapachol; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone; Bethabarra Wood; C.I. 75490; C.I. Natural Yellow 16; Greenhartin; Ipe-tobacco Wood; Lapachol Wood; NSC 11905; NSC 629756; Surinam Greenheart Wood; Taigu Wood; Taiguic Acid; Tecomin. Grades: Highly Purified. CAS No. 84-79-7. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Lapachol
Lapachol is a naphthoquinone that was first isolated from Tabebuia avellanedae (Bignoniaceae). Lapachol shows anti-abscess, anti-ulcer, antileishmanial, anticarcinomic, antiedemic, anti-inflammatory, antimalarial, antiseptic, antitumor, antiviral, antibacterial, antifungal and pesticidal activities. Group: Inhibitors. Alternative Names: Greenhartin. CAS No. 84-79-7. Molecular formula: C15H14O3. Mole weight: 242.27. Appearance: Yellow powder. Purity: 0.97. IUPACName: 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione. Canonical SMILES: CC(=CCC1=C(C2=CC=CC=C2C(=O)C1=O)O)C. Density: 1.2±0.1 g/cm3. Catalog: ACM84797.
Lapachol
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 84-79-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N6961.
Lapaquistat acetate
Lapaquistat acetate, also referred as TAK475, is a squalene synthase inhibitor. As a cholesterol-lowering drug, Lapaquistat acetate decreased plasma cholesterol and triglyceride levels, by lowering lipoproteins containing apoB100. Uses: A novel squalene synthase inhibitor. Synonyms: 2-[1-[2-[(3R,5S)-1-(3-acetyloxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid; (1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid; lapaquistat; TAK 475; TAK-475; TAK475. Grades: >98%. CAS No. 189060-13-7. Molecular formula: C33H41ClN2O9. Mole weight: 645.14.
Lapatinib
Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016; GW2016. CAS No. 231277-92-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50898.
Lapatinib-13C2,15N
Labeled Lapatinib. Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine-13C2, 15N; GSK 572016-13C2,15N; GW 572016-13C2,15N; GW 572016X-13C2,15N. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Lapatinib-13C2,15N Ditosylate
Labeled Lapatinib. Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis (4-methyl Benzene sulfonate) -13C2, 15N Ditosylate; GW-572016F-13C2,15N; Tykerb-13C2,15N Ditosylate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016 ditosylate; GW2016 ditosylate. CAS No. 388082-77-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50898A.
Lapatinib Ditosylate
Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis (4-methyl Benzene sulfonate) Ditosylate; GW-572016F Ditosylate; Tykerb Ditosylate. Grades: Highly Purified. CAS No. 388082-77-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Lapatinib Ditosylate
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Uses: Antineoplastic agents. Synonyms: GW-572016; GW 572016; GW572016. Grades: >98%. CAS No. 388082-77-7. Molecular formula: C29H26ClFN4O4S.2C7H8O3S. Mole weight: 925.46.
Lapatinib ditosylate monohydrate
Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate. CAS No. 388082-78-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-50898B.
Lapatinib ditosylate monohydrate
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C29H26ClFN4O4S ·2(C7H8O3S) ·H2O. CAS No. 388082-78-8. Prepack ID 13289809-100mg. Molecular Weight 943.48. See USA prepack pricing.
Lapatinib, Free Base
ATP-competitive EGFR & ErbB-2 dual tyrosine kinase inhibitor. Lapatinib is an ATP-competitive epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor, with IC(50) values of 10.8 and 9.2nm respectively. It is an orally active drug for treatment of breast cancer and other solid tumors. A free base form of Lapatinib Ditosylate. Lapatinib (as the di-p-toluenesulfonate salt) is the active ingredient in the drug sold under the trade names Tykerb in the US and Tyverb in Europe. This drug has been approved in at least one country to treat advanced metastatic breast cancer in conjunction with the chemotherapy drug Xeloda (generic name, capecitabine). Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine, GSK 572016, GW-572016, GW 572016X, Tykerb, Tyverb. Grades: Highly Purified. CAS No. 231277-92-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Lapatinib Hydroxylamine
a complex used in human metabolism of lapatinib which is a dual kinase inhibitor. Synonyms: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[hydroxy[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine. Grades: > 95%. CAS No. 1360431-86-2. Molecular formula: C29H26ClFN4O5S. Mole weight: 597.07.
Lapatinib Impurity 1
Lapatinib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 202197-26-0. Molecular Formula: C13H11ClFNO. Mole Weight: 251.69. Catalog: APB202197260.
Lapatinib Impurity 10
Lapatinib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393112-45-2. Molecular Formula: C29H26ClFN4O4S. Mole Weight: 581.06. Catalog: APB1393112452.