A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An intermediate in the synthesis of imidazole alkaloids (+)-pilocarpine and (+)-isopilocarpine. Group: Biochemicals. Alternative Names: Imidazole-4-lactic Acid; (S)-2-hydroxy-3-(1(3)H-imidazol-4-yl)-propionic acid Monohydrate; (αS)-α-Hydroxy-1H-imidazole-4-propanoic Acid Monohydrate. Grades: Highly Purified. CAS No. 220919-94-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
L-b-Indanylglycine
L-b-Indanylglycine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
L-Biopterin
L-Biopterin. Group: Biochemicals. Alternative Names: 6-Biopterin; 2-Amino-4-hydroxy-6- (1, 2-dihydroxypropyl) pteridine; L-Erythro-biopterin. Grades: Highly Purified. CAS No. 22150-76-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C9H11N5O3. US Biological Life Sciences.
Worldwide
L-Biopterin
L-Biopterin is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It is produced as an oxidation product by the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). L-Biopterin has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Applications: A cofactor in the production of many neurotransmitters and nitric oxide. Group: Coenzymes. Synonyms: 6-Biopterin; L-Erythro-Biopterin. CAS No. 22150-76-1. Purity: ≥98%. Mole weight: 237.22. Appearance: Powder. Form: Solid. 6-Biopterin; L-Erythro-Biopterin; L-Biopterin; 22150-76-1. Cat No: COEC-068.
L-b-Leucine hydrochloride 98+% (NMR)
L-b-Leucine hydrochloride 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
L-Brompheniramine maleate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102282-22-4. Molecular formula: C20H23BrN2O4. Mole weight: 435.32. Catalog: APB102282224.
L-Buthionine
L-Buthionine. Group: Biochemicals. Alternative Names: S-Butyl-L-homocysteine; L-2-Amino-4-(butylthio)butyric acid. Grades: Highly Purified. CAS No. 13073-21-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H17NO2S. US Biological Life Sciences.
Worldwide
L-Buthionine (S-Butyl-L-homocysteine)
L-Buthionine (S-Butyl-L-homocysteine). Group: Biochemicals. Alternative Names: S-Butyl-L-homocysteine. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
L-Buthionine-(S,R)-sulfoximine
L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 ?M, 8.6 ?M, and 29 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-Buthionine sulfoximine; L-BSO. CAS No. 83730-53-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-106376A.
L-Buthionine-(S,R)-sulfoximine
L-Buthionine-(S,R)-sulfoximine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-4- (S-butylsulfonimidoyl) butanoic acid; L-Buthionine sulfoximine; NSC 326231. Grades: Highly Purified. CAS No. 83730-53-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C8H18N2O3S. US Biological Life Sciences.
Worldwide
L-Buthionine-[S,R]-Sulfoximine
A potent and specific inhibitor of alpha-glutamylcysteine synthetase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
L-Buthionine Sulfoxide
L-Buthionine Sulfoxide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
A cell-permeable, sulfoximine based compound that acts a potent, fast acting, irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. Closely resembles the structure of g-glutamylphosphate cysteine adduct. The inhibition follows the first order kinetics with t1/2 = ~11 sec at saturating inhibitor concentration. Does not affect the activity of glutamine synthetase. Shown to improve the outcome of chemotherapy by lowering the levels of glutathione in cancer cells (IC50 = 1.9, 8.6, and 29uM in melanoma, breast, and ovarian tumor cells, respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 83730-53-4. Pack Sizes: 100mg. Molecular Formula: C?H??N?O?S. US Biological Life Sciences.
Worldwide
LC-2
LC-2 is a potent and first-in-class von Hippel-Lindau-based PROTAC capable of degrading endogenous KRAS G12C, with DC50s between 0.25 and 0.76 ?M[1]. LC-2 covalently binds KRAS G12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRAS G12C degradation leading to suppression of MAPK signaling in both homozygous and heterozygous KRAS G12C cell lines[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2502156-03-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-137516.
LC20, GST tagged from mouse
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
LC3-mHTT-IN-AN1
LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 486443-73-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130258.
LCAHA
LCAHA (LCA hydroxyamide) is a deubiquitinase USP2a inhibitor with IC 50 s of 9.7 μM and 3.7μM in Ub-AMC Assay and Di-Ub Assay, respectively. LCAHA destabilizes Cyclin D1 and induces G0/G1 arrest by inhibiting deubiquitinase USP2a [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCA hydroxyamide. CAS No. 117094-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120458.
L-Canavanine
?98% (TLC), powder, from Canavalia ensiformis. Group: Fluorescence/luminescence spectroscopy.
L-Canavanine sulfate
100mg Pack Size. Group: Amino Acids. Formula: C5H14N4O7S. CAS No. 2219-31-0. Prepack ID 25823277-100mg. Molecular Weight 274.25. See USA prepack pricing.
L-Canavanine sulfate
L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. Uses: Scientific research. Group: Natural products. CAS No. 2219-31-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1581A.
L-Canavanine Sulfate
Canavanine, nitric oxide synthase inhibitor, is an analog of arginine. Both are imported into the cell via the same high-affinity permease, which is encoded by the can1 locus. High-level resistance to canavanine occurs exclusively because of mutation at this locus, but low-level resistance can arise at a number of other loci.Because canavinine is a competitive inhibitor, arginine must be excluded from media used for testing sensitivity to the drug. Canavanine resistance must also be scored under high-nitrogen conditions, such as those provided by SD or SC medium, since the CAN1 permease will then provide the only entry route to the cell for arginine and canavanine. In the presence of low-nitrogen conditions, effectively those provided by YPD medium, the general amino acid permease (GAP) system is induced and arginine and canavanine can also be taken up by this route. In addition, Can r Arg-auxotrophs are viable on YPD but are inviable on synthetic media because they are unable to take up arginine. Group: Biochemicals. Alternative Names: Canavalia ensiformis; O-Guanidino-L-homoserine; L-a-Amino-g-[guanidinooxy]-n-butyric acid. Grades: Molecular Biology Grade. CAS No. 2219-31-0. Pack Sizes: 1g. Molecular Formula: C5H12N4O3; H2SO4, Molecular Weight: 274.25. US Biological Life Sciences.
Worldwide
L-carnitine
L-Carnitine is a natural, vitamin-like nutrient wich plays an important role inhuman metabolism. It is essential in the utilization of fatty acids and in transporting metabolic energy. Alternative Names: CARNITINE, L-;CARNIFEED(R);CARNIKING(R);CAR-OH;ME3-GAMMA-ABU(BETA-HYDROXY)-OH;(R)-BETA-HYDROXY-GAMMA-(TRIMETHYLAMMONIO)BUTYRATE;(R)-3-HYDROXY-4-(TRIMETHYLAMMONIO)BUTYRATE;L-Carnitine Tartrate,L-carnitine,Vitamin BT,L-ca greatrnitine,L-ctheirrnitine. CAS No. 541-15-1. Product ID: PIPE-0099. Molecular formula: C7H15NO3. Mole weight: 161.2. EINECS: 208-768-0. SMILES: C[N+](C)(C)C[C@@H](CC(=O)[O-])O. Appearance: Crystals or Crystalline Powder. Standard: USP. Category: Natural Extract.
L-Carnitine
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-Carnitine; Levocarnitine. CAS No. 541-15-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0399.
L-Carnitine
L-carnitine is a constituent striated muscle and liver, and also a cofactor involved in fatty acid metabolism for transporting fatty acids through the inner mitochondrial membrane. It also acts as an inhibitor of HDAC. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Levocarnitine; Vitamin BT; (R)-Carnitine; Carnitor; ST-198; ST 198; ST198; (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate. Grade: 98%. CAS No. 541-15-1. Molecular formula: C7H15NO3. Mole weight: 161.201.
L-Carnitine
25g Pack Size. Group: Biochemicals, Carbohydrates, Quaternary Ammonium salts. Formula: C7H15NO3. CAS No. 541-15-1. Prepack ID 14710358-25g. Molecular Weight 161.2. See USA prepack pricing.
L-Carnitine-13C Chloride
L-Carnitine-13C Chloride is an essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Applications: An essential cofactor of fatty acid metabolism. Group: Coenzymes. Synonyms: AG-B-72503. CAS No. 541-15-1 (unlabeled). Mole weight: 198.65. AG-B-72503; L-Carnitine-13C Chloride; 541-15-1 (unlabeled). Cat No: COEC-092.
L-Carnitine 97+%
Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado. Group: Biochemicals. Alternative Names: (2R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Inner Salt; L- (3-Carboxy-2-hydroxypropyl) trimethyl Ammonium Hydroxide Inner Salt; (-)-Carnitine; (-)-L-Carnitine; (R)-Carnitine; Levocarnitine; Natrulon RC; ST 198; Vitamin BT. Grades: Highly Purified. CAS No. 541-15-1. Pack Sizes: 100g, 250g, 500g, 1Kg. Molecular Formula: C?H??NO?, Molecular Weight: 161.2. US Biological Life Sciences.
The enzyme is found in gammaproteobacteria such as Proteus sp. and Escherichia coli. It has similar activity with both substrates. Group: Enzymes. Synonyms: CaiB; crotonobetainyl/γ-butyrobetainyl-CoA:carnitine CoA-transferase. Enzyme Commission Number: EC 2.8.3.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3417; L-carnitine CoA-transferase; EC 2.8.3.21; CaiB; crotonobetainyl/γ-butyrobetainyl-CoA:carnitine CoA-transferase. Cat No: EXWM-3417.
L-Carnitine-[d3] chloride
L-Carnitine-[d3] is a labelled L-Carnitine, a non-proteinogenic amino acid and an inhibitor of pyridoxal-dependent enzymes. Synonyms: (-)-Carnitine-d3; Levocarnitine-d3; L-Carnitine-methyl-d3 hydrochloride; L-Carnitine-(methyl-d3) hydrochloride. Grade: ≥99% atom D. CAS No. 350818-62-1. Molecular formula: C7H13D3NO3·Cl. Mole weight: 200.68.
L-Carnitine-d9
L-Carnitine-d 9 is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (R)-Carnitine-d9; Levocarnitine-d9. CAS No. 126827-79-0. Pack Sizes: 1 mg. Product ID: HY-B0399S.
L-Carnitine-d9 chloride
L-Carnitine-d 9 (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride. CAS No. 2687961-04-0. Pack Sizes: 5 mg; 1 mg. Product ID: HY-B2246S.
L-Carnitine FCC/USP/BP/EP
L-Carnitine FCC/USP/BP/EP. CAS No. 541-15-1. Molecular formula: C7H15NO3.