A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An intermediate in the synthesis of imidazole alkaloids (+)-pilocarpine and (+)-isopilocarpine. Group: Biochemicals. Alternative Names: Imidazole-4-lactic Acid; (S)-2-hydroxy-3-(1(3)H-imidazol-4-yl)-propionic acid Monohydrate; (αS)-α-Hydroxy-1H-imidazole-4-propanoic Acid Monohydrate. Grades: Highly Purified. CAS No. 220919-94-8. Pack Sizes: 1g. US Biological Life Sciences.
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L-b-Indanylglycine
L-b-Indanylglycine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
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L-Biopterin
L-Biopterin is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It is produced as an oxidation product by the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). L-Biopterin has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Applications: A cofactor in the production of many neurotransmitters and nitric oxide. Group: Coenzymes. Synonyms: 6-Biopterin; L-Erythro-Biopterin. CAS No. 22150-76-1. Purity: ≥98%. Mole weight: 237.22. Appearance: Powder. Form: Solid. 6-Biopterin; L-Erythro-Biopterin; L-Biopterin; 22150-76-1. Cat No: COEC-068.
L-Biopterin
L-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). It is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Synonyms: L-Biopterin; NSC 339699; NSC-339699; NSC339699; AR 1D8544; AR-1D8544; AR1D8544; LS126316; LS-126316; LS 126316; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone; (-)-Biopterin; 6-Biopterin; Biopterin; L-erythro-Biopterin; NSC 339699; Pterin H B2; (1'R,2'S)-Biopterin; L-erythro-6-(1,2-Dihydroxypropyl)pterin. Grades: >95%. CAS No. 22150-76-1. Molecular formula: C9H11N5O3. Mole weight: 273.22.
L-Biopterin
L-Biopterin. Group: Biochemicals. Alternative Names: 6-Biopterin; 2-Amino-4-hydroxy-6- (1, 2-dihydroxypropyl) pteridine; L-Erythro-biopterin. Grades: Highly Purified. CAS No. 22150-76-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C9H11N5O3. US Biological Life Sciences.
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L-b-Leucine hydrochloride 98+% (NMR)
L-b-Leucine hydrochloride 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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LBM-415
LBM415 (NVP PDF-713), a novel peptide deformylase inhibitor, was tested by reference methods against 2 collections of pathogenic Neisseria being developed for clinical trials as a parenteral and oral agent for treatment of community-acquired respiratory tract disease and serious infections caused by antimicrobial-resistant gram-positive cocci. I. Uses: Pdf inhibitor. Synonyms: LBM-415; LBM 415; LBM415; NVP-PDF-713. (2S) -1- ( (2R) -2- ( (Formylhydroxyamino) methyl) hexanoyl) pyrrolidine-2-carboxylic acid N-(5-fluoro-1-oxopyridin-2-yl)amide. Grades: ≥98%. CAS No. 478913-91-6. Molecular formula: C18H25FN4O5. Mole weight: 396.41.
L-Brompheniramine maleate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102282-22-4. Molecular formula: C20H23BrN2O4. Mole weight: 435.32. Catalog: APB102282224.
L-Buthionine
L-Buthionine. Group: Biochemicals. Alternative Names: S-Butyl-L-homocysteine; L-2-Amino-4-(butylthio)butyric acid. Grades: Highly Purified. CAS No. 13073-21-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H17NO2S. US Biological Life Sciences.
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L-Buthionine (S-Butyl-L-homocysteine)
L-Buthionine (S-Butyl-L-homocysteine). Group: Biochemicals. Alternative Names: S-Butyl-L-homocysteine. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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L-Buthionine-(S,R)-sulfoximine
L-Buthionine-(S,R)-sulfoximine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-4- (S-butylsulfonimidoyl) butanoic acid; L-Buthionine sulfoximine; NSC 326231. Grades: Highly Purified. CAS No. 83730-53-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C8H18N2O3S. US Biological Life Sciences.
Worldwide
L-Buthionine-[S,R]-Sulfoximine
A potent and specific inhibitor of alpha-glutamylcysteine synthetase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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L-Buthionine Sulfone
L-Buthionine Sulfone is a potential inhibitor of human γ-glutamylcysteine synthetase used to sensitize tumors to cytotoxic drugs. Synonyms: (S)-2-Amino-4-(butylsulfonyl)butanoic Acid; (2S)-2-Amino-4-(butylsulfonyl)butanoic Acid. CAS No. 134859-31-7. Molecular formula: C8H17NO4S. Mole weight: 223.29.
L-Buthionine Sulfoxide
L-Buthionine Sulfoxide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
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L-Buthionine sulfoximine
L-Buthionine sulfoximine is an irreversible glutathione-synthesis inhibitor developed as a chemotherapeutic agent. It inhibits glutathione biosynthesis and causes depletion of cellular glutathione levels. Study showed that L-Buthionine sulfoximine synergistically enhanced melphalan activity (inducing 2-4 logs of cell kill) against multiple myeloma cell lines. Synonyms: L-Buthionine-(S,R)-Sulfoximine; (2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid. Grades: ≥98% by HPLC. CAS No. 83730-53-4. Molecular formula: C8H18N2O3S. Mole weight: 222.3.
A cell-permeable, sulfoximine based compound that acts a potent, fast acting, irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. Closely resembles the structure of g-glutamylphosphate cysteine adduct. The inhibition follows the first order kinetics with t1/2 = ~11 sec at saturating inhibitor concentration. Does not affect the activity of glutamine synthetase. Shown to improve the outcome of chemotherapy by lowering the levels of glutathione in cancer cells (IC50 = 1.9, 8.6, and 29uM in melanoma, breast, and ovarian tumor cells, respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 83730-53-4. Pack Sizes: 100mg. Molecular Formula: C?H??N?O?S. US Biological Life Sciences.
Worldwide
LBW242
LBW242 is a Smac mimetic, and potent IAP inhibitor. LBW242 is effective against mutant FLT3 at doses that are physiologically achievable and well tolerated in vivo. LBW242 also enhances the inhibitory effects of PKC412, as well as standard chemotherapeutic agents such as doxorubicin and Ara-c, by acting in an additive-synergistic fashion against mutant FLT3-expressing cells in vitro. LBW242 also sensitizes ovarian cancer cells to the antitumor effects of TRAIL and anticancer drugs commonly used in clinic. Synonyms: N-{(1S)-1-Cyclohexyl-2-oxo-2-[(3aR,7aS)-6-(2-phenylethyl)octahydro-1H-pyrrolo[2,3-c]pyridin-1-yl]ethyl}-N2-methyl-L-alaninamide; Propanamide, N-[(1S)-1-cyclohexyl-2-[(3aR,7aS)-octahydro-6-(2-phenylethyl)-1H-pyrrolo[2,3-c]pyridin-1-yl]-2-oxoethyl]-2-(methylamino)-, (2S)-; (S)-N-((S)-1-cyclohexyl-2-oxo-2-((3aR,7aS)-6-phenethyloctahydro-1H-pyrrolo[2,3-c]pyridin-1-yl)ethyl)-2-(methylamino)propanamide. Grades: ≥95%. CAS No. 867324-12-7. Molecular formula: C27H42N4O2. Mole weight: 454.65.
LBX192
LBX192 is a Liver Targeted Glucokinase Activator. It can activate the GK enzyme in vitro at low nM concentrations and reduce glucose levels during an oral glucose tolerance test in normal as well as diabetic mice. Synonyms: LBX192; LBX 192; LBX-192; NVP-LBX192; NVP-LBX-192; NVP-LBX 192; (R)-3-cyclopentyl-N-(5-methoxythiazolo[5,4-b]pyridin-2-yl)-2-(4-((4-methylpiperazin-1-yl)sulfonyl)phenyl)propanamide. Grades: 98%. CAS No. 866772-52-3. Molecular formula: C26H33N5O4S2. Mole weight: 543.70.
LC20, GST tagged from mouse
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
LCAHA
LCAHA (LCA hydroxyamide) is a deubiquitinase USP2a inhibitor with IC 50 s of 9.7 μM and 3.7μM in Ub-AMC Assay and Di-Ub Assay, respectively. LCAHA destabilizes Cyclin D1 and induces G0/G1 arrest by inhibiting deubiquitinase USP2a [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCA hydroxyamide. CAS No. 117094-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120458.
?98% (TLC), powder, from Canavalia ensiformis. Group: Fluorescence/luminescence spectroscopy.
L-Canavanine sulfate
The sulfate salt form of L-Canavanine, a homoserine analog, has been found to be a NO synthase inhibitor. Synonyms: L-2-Amino-4-(guanidiooxy)butyric acid sulfate. Grades: ≥95% by HPLC. CAS No. 2219-31-0. Molecular formula: C5H12N4O3.H2SO4. Mole weight: 274.25.
L-Canavanine sulfate
100mg Pack Size. Group: Amino Acids. Formula: C5H14N4O7S. CAS No. 2219-31-0. Prepack ID 25823277-100mg. Molecular Weight 274.25. See USA prepack pricing.
L-Canavanine sulfate
L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. Uses: Scientific research. Group: Natural products. CAS No. 2219-31-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1581A.
L-Canavanine Sulfate
Canavanine, nitric oxide synthase inhibitor, is an analog of arginine. Both are imported into the cell via the same high-affinity permease, which is encoded by the can1 locus. High-level resistance to canavanine occurs exclusively because of mutation at this locus, but low-level resistance can arise at a number of other loci.Because canavinine is a competitive inhibitor, arginine must be excluded from media used for testing sensitivity to the drug. Canavanine resistance must also be scored under high-nitrogen conditions, such as those provided by SD or SC medium, since the CAN1 permease will then provide the only entry route to the cell for arginine and canavanine. In the presence of low-nitrogen conditions, effectively those provided by YPD medium, the general amino acid permease (GAP) system is induced and arginine and canavanine can also be taken up by this route. In addition, Can r Arg-auxotrophs are viable on YPD but are inviable on synthetic media because they are unable to take up arginine. Group: Biochemicals. Alternative Names: Canavalia ensiformis; O-Guanidino-L-homoserine; L-a-Amino-g-[guanidinooxy]-n-butyric acid. Grades: Molecular Biology Grade. CAS No. 2219-31-0. Pack Sizes: 1g. Molecular Formula: C5H12N4O3; H2SO4, Molecular Weight: 274.25. US Biological Life Sciences.
Worldwide
L-Carnitine
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-Carnitine; Levocarnitine. CAS No. 541-15-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0399.
L-Carnitine
L-carnitine is a constituent striated muscle and liver, and also a cofactor involved in fatty acid metabolism for transporting fatty acids through the inner mitochondrial membrane. It also acts as an inhibitor of HDAC. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Levocarnitine; Vitamin BT; (R)-Carnitine; Carnitor; ST-198; ST 198; ST198; (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate. Grades: 98%. CAS No. 541-15-1. Molecular formula: C7H15NO3. Mole weight: 161.201.
L-Carnitine
25g Pack Size. Group: Biochemicals, Carbohydrates, Quaternary Ammonium salts. Formula: C7H15NO3. CAS No. 541-15-1. Prepack ID 14710358-25g. Molecular Weight 161.2. See USA prepack pricing.