A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
L-Cystine dihydrochloride is the dihydrochloride salt form of L-Cystine (HY-N0394). L-Cystine dihydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine dihydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine dihydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine dihydrochloride is promising for research of cystinuria and kidney stones [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Peptides. CAS No. 30925-07-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W009203.
L-Cystine dihydrochloride
100g Pack Size. Group: Biochemicals. Formula: C6H12N2O4S2 · 2HCl. CAS No. 30925-07-6. Prepack ID 22601431-100g. Molecular Weight 313.22. See USA prepack pricing.
L-Cystine dihydrochloride
L-Cystine dihydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 13059-63-7. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C6H14Cl2N2O4S2. US Biological Life Sciences.
Worldwide
L-Cystine dihydrochloride
from non-animal source, BioReagent, suitable for cell culture, ?98.0% dry basis. Group: Fluorescence/luminescence spectroscopy.
L-Cystine dihydrochloride
L-Cystine is a non-essential amino acid for human development. L-Cystine is formed by the dimerization of two cysteines through the sulfur. Synonyms: L-Cystine, hydrochloride (1:2); Cystine, dihydrochloride, L-; Cystine dihydrochloride; (2R,2'R)-3,3'-disulfanediylbis(2-aminopropanoic acid) dihydrochloride. Grade: ≥95%. CAS No. 30925-07-6. Molecular formula: C6H12N2O4S2.2HCl. Mole weight: 313.22.
L-Cystine Dihydrochloride (non-animal)
Non-animal sourced L-cystine is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. Group: Biochemicals. Alternative Names: (H-Cys-OH)2.2HCl. Grades: Cell Culture Grade. CAS No. 30925-07-6. Pack Sizes: 25g, 100g, 500g, 1Kg. Molecular Formula: C6H12N2O4S2 2HCl, Molecular Weight: 313.22. US Biological Life Sciences.
Worldwide
L-Cystine dihydrochloride, non-animal 99+%
L-Cystine dihydrochloride, non-animal 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
L-Cystine dimethyl ester dihydrochloride
L-Cystine dimethyl ester dihydrochloride serves as an efficacious antioxidant, exhibiting commendable immunomodulatory, metabolic and cytoprotective potential. Its application is extended towards abating oxidative stress, addressing cardiovascular complications, and counteracting hepatic insult instigated by noxious agents. In essence, this compound offers a multifaceted therapeutic approach to sustain homeostatic balance in cellular milieu. Synonyms: Dimethyl L-cystinate dihydrochloride; (2R,2'R)-Dimethyl 3,3'-disulfanediylbis(2-aminopropanoate) dihydrochloride; Dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate) dihydrochloride; NSC 161614; L-cysteine methyl ester (1->1')-disulfide compound with L-cysteine methyl ester hydrochloride. Grade: >95%. CAS No. 32854-09-4. Molecular formula: C8H18Cl2N2O4S2. Mole weight: 341.28.
L-Cystine dimethyl ester dihydrochloride
L-Cystine dimethyl ester dihydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 32854-09-4. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
L-Cystine-dimethyl Ester Dihydrochloride
L-Cystine-dimethyl Ester Dihydrochloride. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
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L-Cystine Disodium Anhydrous (H-L-Cys-OH*NH2)
L-Cystine Disodium Anhydrous (H-L-Cys-OH*NH2). Group: Biochemicals. Alternative Names: H-L-Cys-OH*NH2; 2-amino-3-[ (2-amino-2-carboxylatoethyl) disulfanyl]propanoate Disodium. Grades: Cell Culture Grade. CAS No. 647404-23-0. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C6H10N2O4S2Na2, Molecular Weight: 284.3. US Biological Life Sciences.
L-Cystine Disodium Salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 64704-23-0. Pack Sizes: 500mg, 1g. Molecular Formula: C6H10N2Na2O4S2, Molecular Weight: 284.26. US Biological Life Sciences.
Worldwide
L-Cystine Disodium Salt Monohydrate
L-Cystine Disodium Salt Monohydrate. Synonyms: 7308AH. CAS No. 199329-53-8. Molecular formula: C6H10N2O4S2·2Na·H2O. Mole weight: 302.28.
L-Cystine disodium salt synthetically derived
100g Pack Size. Group: Amino Acids. Formula: C6H10N2Na2O4S2. CAS No. 64704-23-0. Prepack ID 52105905-100g. Molecular Weight 284.26. See USA prepack pricing.
L-Cystine from non-animal source
L-Cystine from non-animal source. Uses: L-cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. it has been used in several techniques, such as hplc-fd, uhplc-uv, uhplc-ms, and triple quadrupole tandem mass spectrometry (uhplc-ms/ms), to differentiate bmaa (β-n-methylamino-l-alanine), the cyanobacterial neurotoxin, from other diamino acids. l-cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development. Additional or Alternative Names: (R,R)-3,3'-Dithiobis(2-aminopropionicacid). Product Category: Amino Acids. CAS No. 56-89-3. Molecular formula: [-SCH2CH(NH2)CO2H]2. Mole weight: 240.3. Canonical SMILES: N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O. ECNumber: 200-296-3. Product ID: ACM56893-3. Alfa Chemistry ISO 9001:2015 Certified.
L-Cystine, ≥98% (TLC), crystalline
L-Cystine, ≥98% (TLC), crystalline. Uses: L-cystine has been used in in vitro cystine solubility assay to identify potential drugs that influence cystine solubility. it is also used as a supplement of phosphate-buffered saline to slice and wash periprosthetic tissues. Additional or Alternative Names: (R,R)-3,3'-Dithiobis(2-aminopropionicacid). Product Category: Amino Acids. CAS No. 56-89-3. Molecular formula: [-SCH2CH(NH2)CO2H]2. Mole weight: 240.3. Canonical SMILES: N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O. ECNumber: 200-296-3. Product ID: ACM56893-4. Alfa Chemistry ISO 9001:2015 Certified.
L-Cystine,≥99.7% (TLC)
L-Cystine,≥99.7% (TLC). Uses: L-cystine has been used to prepare stock solution which in turn is utilized for determining the l-cysteine and l-cystine in pharmaceutical preparations as well as in urine samples by using spectrofluorimetric flow injection method. Additional or Alternative Names: (R,R)-3,3'-Dithiobis(2-aminopropionicacid). Product Category: Amino Acids. CAS No. 56-89-3. Molecular formula: [-SCH2CH(NH2)CO2H]2. Mole weight: 240.3. Canonical SMILES: N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O. ECNumber: 200-296-3. Product ID: ACM56893-5. Alfa Chemistry ISO 9001:2015 Certified.
L-Cystine hydrochloride
L-Cystine hydrochloride is an orally active extracellular form of L-Cysteine (HY-Y0337), occurring in proteins of plants and animals. L-Cystine hydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-Cystine hydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine hydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine hydrochloride is promising for research of cystinuria and kidney stones [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Peptides. CAS No. 34760-60-6. Pack Sizes: 1 g; 5 g. Product ID: HY-W009356.
L-Cystine hydrochloride solution
10 mM amino acid in 0.1 M HCl, analytical standard. Group: Amino acid, peptide & protein standards.
L-Cytidine
L-Cytidine. Group: Biochemicals. Alternative Names: 1- (b-L-ribofuranosyl) cytosine. Grades: Highly Purified. CAS No. 26524-60-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C9H13N3O5. US Biological Life Sciences.
Worldwide
LCZ696 (valsartan + sacubitril) impurity 19
LCZ696 (valsartan + sacubitril) impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341546.
LCZ696 (valsartan + sacubitril) impurity 20
LCZ696 (valsartan + sacubitril) impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341568.
LCZ696 (valsartan + sacubitril) impurity 21
LCZ696 (valsartan + sacubitril) impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341524.
LD78 beta (CCL3L1) human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
L-DABA
L-DABA, (L-2,4-Diaminobutyric acid) is a noncompetitive GABA transaminase inhibitor (IC50 > 500 μM) with antitumor activity in vivo and in vitro. Synonyms: (2S)-2,4-diaminobutanoic acid; 2,4-diaminobutyric acid; 2,4-diaminobutyric acid dihydrochloride, (+-)-isomer; 2,4-diaminobutyric acid dihydrochloride, (S)-isomer; 2,4-diaminobutyric acid monohydrochloride, (+-)-isomer; 2,4-diaminobutyric acid monohydrochloride, (S)-isomer; 2,4-diaminobutyric acid, (+)-isomer; 2,4-diaminobutyric acid, (+-)-isomer; 2,4-diaminobutyric acid, (R)-isomer; 2,4-diaminobutyric acid, (S)-isomer; L-2,4-diaminobutyric acid. CAS No. 1758-80-1. Molecular formula: C4H10N2O2. Mole weight: 118.13.
Ldao
Ldao. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N,N-dimethyl-1-dodecanamine, N-oxide; Dimethyldodecylamine N-oxide; Lauramine oxide; Lauryldimethylamine oxide; N-Lauryldimethylamine N-oxide. Appearance: A crystalline solid. CAS No. 1643-20-5. Molecular formula: C14H31NO. Mole weight: 229.4. Purity: ≥95%. IUPACName: N,N-dimethyldodecan-1-amine oxide. Canonical SMILES: CCCCCCCCCCCC[N+](C)(C)[O-]. Density: 0.996 g/mL at 20 °C. ECNumber: 216-700-6. Product ID: ACM1643205. Alfa Chemistry ISO 9001:2015 Certified. Categories: Laos.
LDC000067
LDC000067 is a highly specific CDK9 inhibitor with an IC50 value of 44±10 nM in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LDC067. CAS No. 1073485-20-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15878.
LDC1267 is a highly selective TAM (Tyro3, Axl and Mer) kinase inhibitor with IC50s of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively[1].5>. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361030-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12494.
LDC7559
LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407782-01-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111674.
L-Dehydro ascorbic acid
L-Dehydro ascorbic acid. Group: Biochemicals. Alternative Names: Dehydro-L-ascorbic acid; L-threo-2,3-hexodiulosonic acid gamma-lactone; Oxidized ascorbic acid. Grades: Highly Purified. CAS No. 490-83-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H6O6. US Biological Life Sciences.
Worldwide
L-Dehydro Ascorbic Acid-[13C6]
L-Dehydro Ascorbic Acid-[13C6] is the labelled analogue of L-Dehydro Ascorbic Acid, which is the reversibly oxidized form of ascorbic acid. Synonyms: L-Dehydro Ascorbic Acid-13C6; Dehydro-L-ascorbic Acid-13C6; L-threo-2,3-Hexodiulosonic Acid-13C6 γ-Lactone; Oxidized Ascorbic Acid-13C6; Oxidized Vitamin C-13C6. CAS No. 1217529-45-7. Molecular formula: [13C]6H6O6. Mole weight: 180.06.
L-demethylnoviosyl transferase
The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic, novobiocin. Group: Enzymes. Synonyms: novM (gene name); dTDP-β-L-noviose:novobiocic acid 7-O-noviosyltransferase; L-noviosyl transferase. Enzyme Commission Number: EC 2.4.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2537; L-demethylnoviosyl transferase; EC 2.4.1.302; novM (gene name); dTDP-β-L-noviose:novobiocic acid 7-O-noviosyltransferase; L-noviosyl transferase. Cat No: EXWM-2537.
L-Deoxyalliin
L-Deoxyalliin. Group: Biochemicals. Alternative Names: S-2-Propen-1-yl-L-cysteine; (+)-S-Allylcysteine; 3-(Allylthio)-L-alanine; Deoxyalliin; NSC 96449; S-(2-Propenyl)-L-cysteine; S-2-Propenylcysteine; S-Allyl-L-cysteine; S-Allylcysteine. Grades: Highly Purified. CAS No. 21593-77-1. Pack Sizes: 10mg. Molecular Formula: C6H11NO2S, Molecular Weight: 161.22. US Biological Life Sciences.
Worldwide
LDH-IN-1
LDH-IN-1 is a novel pyrazole-based inhibitor of human lactate dehydrogenase (LDH) with IC50s of 32 and 27 nM for LDHA and LDHB, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1964515-43-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111108.
L-Dicentrine
A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion. Group: Biochemicals. Alternative Names: (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; 9,10-Dimethoxy-1,2-(methylenedioxy)-6a β-aporphine; (R)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; (-)-Dicentrine; (R)-(-)-Dicentrine; NSC 251699. Grades: Highly Purified. CAS No. 28832-07-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-Dicentrine-d3
L-Dicentrine-d3. Group: Biochemicals. Alternative Names: (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline-d3; 9,10-Dimethoxy-1,2-(methylenedioxy)-6a β-aporphine-d3; (R)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline-d3; (-)-Dicentrine-d3; (R)-(-)-Dicentrine-d3; NSC 251699-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C20H18D3NO4, Molecular Weight: 342.4. US Biological Life Sciences.
Worldwide
L-Dierucoyl Lecithin
L-Dierucoyl Lecithin is a phospholipid that is used in the formation of netural lipid bilayer membranes for the purposes of research and experimentation in the fields of biology and biochemistry. L-Dierucoyl Lecithin is a derivative of Lecithin, a phospholipid that is an important component of naturally occurring, biological membranes. Group: Biochemicals. Grades: Highly Purified. CAS No. 51779-95-4. Pack Sizes: 250mg, 2.5g. Molecular Formula: C52H100NO8P, Molecular Weight: 898.33. US Biological Life Sciences.
Worldwide
L-Dierucoyl Lecithin-D9
L-Dierucoyl Lecithin-D9 is a labelled analogue of L-Dierucoyl Lecithin (D441945). L-Dierucoyl Lecithin is a phospholipid that is used in the formation of netural lipid bilayer membranes for the purposes of research and experimentation in the fields of biology and biochemistry. L-Dierucoyl Lecithin is a derivative of Lecithin, a phospholipid that is an important component of naturally occurring, biological membranes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H39D9NO8P, Molecular Weight: 542.69. US Biological Life Sciences.
Worldwide
L-Dihydroorotic acid
L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase ( DHODH ). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 5988-19-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W015495.
L-Dithiothreitol. Group: Biochemicals. Grades: Reagent Grade. CAS No. 16096-97-2. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
L-Dithiothreitol
L-Dithiothreitol (DTT) is a reducing agent commonly used in various biochemical applications to break disulfide bonds in proteins, thereby denaturing proteins or preventing the formation of unwanted aggregates. DTT has a unique chemical property that cleaves the sulfur-sulfur bond in the disulfide bond to form a sulfhydryl group. This makes it a useful tool for protein purification, enzyme assays, and protein structure studies. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 16096-97-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15917A.
L-(-)-Dithiothreitol
L-(-)-Dithiothreitol. Group: Biochemicals. Alternative Names: (-)-Cleland's Reagent; L-DTT. Grades: Highly Purified. CAS No. 16096-97-2. Pack Sizes: 1g, 2g, 5g. Molecular Formula: C4H10O2S2. US Biological Life Sciences.
Worldwide
LDL-IN-2
LDL-IN-2 (compound 3) is an antioxidant against copper mediated low-density lipoproteins ( LDL ) oxidation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 778624-05-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120651.
Ldn193189. Uses: Designed for use in research and industrial production. Additional or Alternative Names: S2618_Selleck; cc-233; UNII-W69H5YQU9O; 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline hydrochloride DM-3189. Appearance: solid. CAS No. 1062368-24-4. Molecular formula: C25H22N6. Mole weight: 406.48. Purity: 98%+. IUPACName: 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. Canonical SMILES: C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3. Product ID: ACM1062368244. Alfa Chemistry ISO 9001:2015 Certified.
LDN193189
LDN193189 is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC 50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM-3189. CAS No. 1062368-24-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-12071.
LDN-193189 dihydrochloride
LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC 50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM-3189 dihydrochloride. CAS No. 1435934-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12071B.
LDN193189 (DM-3189)
LDN193189 (DM-3189). Group: Biochemicals. Alternative Names: 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinolone. Grades: Highly Purified. CAS No. 1062368-24-4. Pack Sizes: 10mg. Molecular Formula: C25 H22 N6, Molecular Weight: 406.5. US Biological Life Sciences.
LDN 209929 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LDN-211904
LDN-211904 modulates the biological activity of EphB3 receptor tyrosine kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
A pyrazolo[1,5-a]pyridine derivative that acts as an potent and reversible EphB3 receptor tyrosine kinase inhibitor with an IC50 of 79nM with good mouse liver microsomal stability and aqueous solubility. Shown to suppress EphB3-induced autophosphorylation of EphB3 receptor at 10uM in cells. When profiled against a panel of 288 kinases at 5uM, found to also inhibit most of the Eph (Erythropoietin-producing hepatocellular carcinoma) receptor kinases including EphA1, EphA2, EphA3, EphA4, EphA5, EphA8, EphB1, EphB2, EphB3, EphB4 and other tyrosine kinases, but not EphA6 and EphA7, and is non-inhibitory towards non-RTK kinases screened except for p38α, p38b, and Qik. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 444.9. US Biological Life Sciences.
Worldwide
LDN-211904 oxalate
LDN-211904 oxalate is a potent and reversible EphB3 inhibitor with an IC50 of 79 nM. LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. LDN-211904 oxalate with Cetuximab (HY-P9905) could be effective in inhibiting STAT3-activated colorectal cancer (CRC) stemness and Cetuximab resistance in CRC[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1198408-78-4. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-107460.
LDN 212320
LDN 212320. Group: Biochemicals. Grades: Purified. CAS No. 894002-50-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LDN-212854
LDN-212854 is a bone morphogenetic protein (BMP) inhibitor that potently inhibits ALK2 (IC50: 1.3 nM). LDN-212854 also inhibits ALK1 (IC50: 2.40 nM). LDN-212854 can be used in the research of fibrodysplasia ossificans progressive and cancers, such as hepatocellular carcinoma (HCC)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1432597-26-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15897.
LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) [1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627503-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16712.
LDN 27219. Group: Biochemicals. Grades: Purified. CAS No. 312946-37-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LDN-27219
LDN-27219 is a reversible, slow-binding inhibitor of TGase. LDN-27219 inhibits human TGase with an IC50 value of 0.6 ?M. LDN-27219 effectively decreases blood pressure and induces vasodilation, it can be used for the research of cardiovascular disease[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312946-37-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16693.