American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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L-[5-13C]Xylose Quick inquiry Where to buy Suppliers range | L-[5-13C]Xylose. Group: Biochemicals. Grades: Highly Purified. CAS No. 478506-64-8. Pack Sizes: 2.5mg. Molecular Formula: C413CH10O5, Molecular Weight: 151.12. US Biological Life Sciences. | Worldwide |
L524-0366 Quick inquiry Where to buy Suppliers range | L524-0366 Inhibitor. Uses: Scientific use. Product Category: T8570. CAS No. 951612-19-4. | |
L-5,5-Dimethylthiazolidine-4-carboxylic Acid Quick inquiry Where to buy Suppliers range | Found to act on the cell membrane of tumor cells, possible causing a reverse transformation to normal cells through restoration of contact inhibition. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
L-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID Quick inquiry Where to buy Suppliers range | 72778-00-8, L-5,5-Dimethylthiazolidine-4-carboxylic acid, (R)-5,5-Dimethylthiazolidine-4-carboxylic acid, (4R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 3,3-Dimethyl-4-thiaproline, (R)-4-Carboxy-5,5-dimethylthiazolidine, SCHEMBL950964, CHEMBL1229504, DTXSID20420827, MFCD00070264, AKOS006272974, AS-67222, (R)-5,5-Dimethyl-4-thiazolidinecarboxylic Acid, (R)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Q27447757. | |
L-5 Hydroxytryptophan Quick inquiry Where to buy Suppliers range | L-5 Hydroxytryptophan. | CA, FL & NJ |
L5K5W Quick inquiry Where to buy Suppliers range | L5K5W. Uses: Antimicrobial Peptides. Product ID: AF109. | |
L5K5W6 Quick inquiry Where to buy Suppliers range | L5K5W6 is a synthetic antibacterial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Lys-Lys-Leu-Leu-Lys-Trp-Leu-Lys-Lys-Leu-Leu-NH2. Grades: 96.3%. Molecular formula: C71H128N18O11. Mole weight: 1409.92. | |
L-5-Methyltetrahydrofolate calcium Quick inquiry Where to buy Suppliers range | L-5-Methyltetrahydrofolate calcium. Group: Biochemicals. Alternative Names: Calcium levomefolate; N-[4-[[ (2-Amino-1, 4, 5, 6, 7, 8-hexahydro-5-methyl-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic acid calcium salt. Grades: Highly Purified. CAS No. 151533-22-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C20H23N7O6·Ca. US Biological Life Sciences. | Worldwide |
L-5-Methyltetrahydrofolate Calcium Quick inquiry Where to buy Suppliers range | L-5-Methyltetrahydrofolate Calcium. CAS No. 151533-2-1. Categories: levomefolate calcium; 151533-22-1. | CA, FL & NJ |
L-5-methyluridine Quick inquiry Where to buy Suppliers range | L-5-Methyluridine is a nucleoside analogue employed, serving as a potent therapeutic compound against afflictions caused by viral compounds, including hepatitis B and hepatitis C. It operates by impeding viral replication mechanisms, thereby exhibiting remarkable antiviral prowess. This specific product holds immense potential for application within the realms of antiviral drug investigation, as well as the examination of nucleoside metabolism intricacies and nucleic acid synthesis processes. Synonyms: beta-L-ribofuranosyl thymine; 5-methyl-1-(beta-L-ribofuranosyl)uracil; L-5-Me-rU; 1-beta-l-ribofuranosylthymine; 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-beta-L-ribofuranosyl-; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; L-5-Me-Uridine. Grades: ≥97% by HPLC. CAS No. 642082-80-2. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
L605 Cobalt Base Quick inquiry Where to buy Suppliers range | L605 Cobalt Base. Uses: For analytical and research use. Group: Metal alloys. Catalog: APS009272. Shipping: Room Temperature. | |
L-651,582 Quick inquiry Where to buy Suppliers range | L-651,582 is a novel inhibitor of both cAMP-phosphodiesterases and GMP-phosphodiesterases. It is also an orally active calcium channel blocker. It prevents oxidative phosphorylation in cancer cells and exhibits inhibition of pro-inflammatory cytokines in tumor associated macrophages. It may be used as a potential anti-cancer drug. It ameliorates experimental colitis by inhibiting nuclear factor-κB activation, colonic fibrosis and cytokine production. It has antimetastatic, antiangiogenic and antiproliferative activity in vivo. It displays selectivity towards numerous mismatch repair-deficient tumor cell lines in vitro. It blocks intracellular and mitochondrial calcium entry and flux, resulting in inhibition of calcium-release-activated calcium channel (CRAC) function, cell proliferation and maintenance of mitochondrial membrane potential. Synonyms: Carboxyamidotriazole; CAI; RFE-007; NSC-609974; L-651582; RFE007; NSC609974; L651582; 5-Amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]-1H-1,2,3-triazole-4-carboxamide. Grades: ≥98% by HPLC. CAS No. 99519-84-3. Molecular formula: C17H12Cl3N5O2. Mole weight: 424.67. | |
L-651,582 Quick inquiry Where to buy Suppliers range | L-651,582. Group: Biochemicals. Grades: Purified. CAS No. 99519-84-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
L-655,240 Quick inquiry Where to buy Suppliers range | L-655,240. Group: Biochemicals. Grades: Purified. CAS No. 103253-15-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
L-655,240 Quick inquiry Where to buy Suppliers range | L-655,240 is a potent and selective antagonist of thromboxane and prostaglandin endoperoxide receptor. It also blocks TP-mediated bronchoconstriction in vivo and platelet aggregation ex vivo. Synonyms: 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid. Grades: ≥98%. CAS No. 103253-15-2. Molecular formula: C21H21ClFNO2. Mole weight: 373.9. | |
L-655,708 Quick inquiry Where to buy Suppliers range | L-655,708. Group: Biochemicals. Grades: Purified. CAS No. 130477-52-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
L-655,708 Quick inquiry Where to buy Suppliers range | L-655,708, an inverse agonist of α5 subunit involved in GABAA receptor, has been found to exhibit cognitive performance improvement in biological studies. Uses: L-655,708, is an inverse agonist of α5 subunit involved in gabaa receptor and has been found to exhibit cognitive performance improvement in biological studies. Synonyms: L-655708; L655708; L 655708; L-655,708; L655,708; L 655,708; FG-8094; FG 8094; FG8094; ETHYL (S)-11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLATE;L-655,708;11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLIC ACID, ETHYL ESTER;11,12,1. Grades: >99 %. CAS No. 130477-52-0. Molecular formula: C18H19N3O4. Mole weight: 341.36. | |
L 656224 Quick inquiry Where to buy Suppliers range | L 656224 is a 5-lipoxygenase (5-LO) inhibitor. Synonyms: L-656224. Grades: ≥98% by HPLC. CAS No. 102612-16-8. Molecular formula: C20H21ClO3. Mole weight: 344.8. | |
L67 Quick inquiry Where to buy Suppliers range | L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC50 values of 10 μM and 10 μM.). Synonyms: L67; L-67; L 67. Grades: 98%. CAS No. 325970-71-6. Molecular formula: C16H14Br2N4O4. Mole weight: 486.12. | |
L-670,596 Quick inquiry Where to buy Suppliers range | L-670,596 is a potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist with IC50 value of 5.5 nM. It displays ALDH1A1 specific inhibitory activity. It inhibits human platelet aggregation and U-44069-induced contractions of guinea pig trachea in vitro. It also inhibits thromboxane-mediated endothelial cell death. It is orally active in vivo. Synonyms: L-670596; L 670596; L670596; (-)-6-8-Difluoro-2,3,4,9-tetrahydro-9-[[4-(methylsulfonyl)phenyl]methyl]-1H-carbazole-1-acetic acid; 2-[6,8-Difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid. Grades: ≥98% by HPLC. CAS No. 121083-05-4. Molecular formula: C22H21F2NO4S. Mole weight: 433.47. | |
L-670,596 Quick inquiry Where to buy Suppliers range | L-670,596. Group: Biochemicals. Grades: Purified. CAS No. 121083-05-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
L-671776 Quick inquiry Where to buy Suppliers range | L-671776 is a myo-inositol monophosphatase (IMPase) inhibitor produced by Memnoniella echinata. Synonyms: L 671776; 4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzofuran-2,1'-naphthalene]-5-carbaldehyde; L-671,776; Spiro(benzofuran-2(3H),1'(2'H)-naphthalene)-5-carboxaldehyde, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8'a-tetramethyl-. Grades: >98%. CAS No. 134313-74-9. Molecular formula: C23H32O5. Mole weight: 388.50. | |
L-681176 Quick inquiry Where to buy Suppliers range | L-681176 is originally isolated from Streptomyces sp. MA 5143a. It has the activity of inhibiting angiotensin transferase. Synonyms: L-681,176. CAS No. 91386-17-3. Molecular formula: C12H23N5O7. Mole weight: 349.34. | |
L-681217 Quick inquiry Where to buy Suppliers range | A glycolipid-type antibiotic related to the efrotomycin class; isolated from a streptomyces sp.; shows broad spectrum antibiotic activity against gram positive and gram negative bacteria. Synonyms: L 681217; Antibiotic L-681217; 2,4,6-Heptatrienoic acid, 7-(tetrahydro-3-hydroxy-5-(2-methoxy-1,3-dimethyl-7-((1-oxo-2-(tetrahydro-2,4,5-trihydroxy-5-methyl-6-(1,3-pentadienyl)-2H-pyran-2-yl)butyl)amino)-3,5-heptadienyl)-2-furanyl)-. Grades: >95% by HPLC. CAS No. 93522-10-2. Molecular formula: C36H53NO10. Mole weight: 659.80. | |
L-685,458 Quick inquiry Where to buy Suppliers range | L-685,458 is a potent and selective inhibitor of γ-secretase (IC50 = 17 nM) that shows 50-fold selectivity over a variety of aspartyl proteases. It also inhibits Aβ40 and Aβ42 peptides (in human neuroblastoma cells: IC50=48 and 67 nM respectively). Uses: Gamma secretase inhibitors and modulators. Synonyms: L-685458; tert-butyl N-[(2S,3R,5R)-6-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate. Grades: >98%. CAS No. 292632-98-5. Molecular formula: C39H52N4O6. Mole weight: 672.85. | |
L-685,458 Quick inquiry Where to buy Suppliers range | L-685,458. Group: Biochemicals. Grades: Purified. CAS No. 292632-98-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
L-685,458 ((5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucyl-L-phenylalaninamide) Quick inquiry Where to buy Suppliers range | Cell-permeable. A potent and selective γ-secretase inhibitor (IC50 = 17 nM). Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of A β40 and A β42 peptides (IC50 values are 48 and 67nM respectively in human neuroblastoma cells). Group: Biochemicals. Alternative Names: (5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucyl-L-phenylalaninamide. Grades: Highly Purified. CAS No. 292632-98-5. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
L 687781 Quick inquiry Where to buy Suppliers range | L 687781, an inhibitor of β-1,3-D-glucan synthase, is originally isolated from Dictyochaeta simplex. It also has anti-Candida fungal activity and has some effects on Pneumocystis carinii. Synonyms: Hexopyranose, 1,6'-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4-decadienyl)hexopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-1-oxo-2,4,6,8,10-hexadecapentaenoate). CAS No. 130304-58-4. Molecular formula: C47H66O17. Mole weight: 903.01. | |
L-689502 Quick inquiry Where to buy Suppliers range | A potent inhibitor of HIV-l protease (IC50= 1 nM). Synonyms: L 689502; L-689502; L689502; L-689,502; L 689,502; L689,502; tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]-6-oxo-1-phenylhexan-2-yl]carbamate; L 689502; L-689,502. Grades: ≥98% (HPLC). CAS No. 138483-63-3. Molecular formula: C39H51N3O7. Mole weight: 673.84. | |
L-689,560 Quick inquiry Where to buy Suppliers range | L-689,560 is a potent antagonist at the glycine-NMDA receptor site. It is a bioactive chemical. Synonyms: L689560; L 689560; L-689560; trans-(±)-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; rel-(2R,4S)-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; (2R,4S)-rel-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; trans-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline; (2S,4R)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 139051-78-8. Molecular formula: C17H15Cl2N3O3. Mole weight: 380.23. | |
L-690,330 Quick inquiry Where to buy Suppliers range | L-690,330 is a potent inositol monophophatase (IMPase) inhibitor in vitro and in vivo. It induces autophagy in COS-7 cells independently of mTOR inhibition. It is stable to hydrolysis. Synonyms: L690330; L 690330; L-690330. [1- (4-Hydroxyphenoxy) ethylidene]bisphosphonic Acid; P, P'-[1- (4-Hydroxyphenoxy) ethylidene]bis[phosphonic acid]; L 690330. CAS No. 142523-38-4. Molecular formula: C8H12O8P2. Mole weight: 298.13. | |
L-690,488 Quick inquiry Where to buy Suppliers range | L-690,488 is a cell-permeable prodrug of the L-690,330, which is a potent bisphosphonate inositol monophophatase inhibitor. It penetrates cells more effectively than its metabolite. Synonyms: L-690,488; L 690,488; L690488; L 690488; 1-[ (4-Hydroxyphenoxy) ethylidene]bis[phosphinylidynebis (oxymethylene) ]-2, 2-dimethylpropanoate. Grades: ≥98% by HPLC. CAS No. 142523-14-6. Molecular formula: C32H52O16P2. Mole weight: 754.70. | |
L 691816 Quick inquiry Where to buy Suppliers range | L 691816 is a 5-lipoxygenase (5-LO) inhibitor. Synonyms: 1-(4-Chlorobenzyl)-2-(2,2-Dimethyl-3-(1H-Tetrazol-5-Yl)Propyl)-4-Methyl-6-((5-Phenylpyridin-2-Yl)Methoxy)-4,5-Dihydro-1H-Thiopyrano[2,3,4-Cd]Indole; L-691816; L691816. Grades: ≥98% by HPLC. CAS No. 150461-07-7. Molecular formula: C36H35ClN6OS. Mole weight: 635.2. | |
L-692,585 Quick inquiry Where to buy Suppliers range | L-692,585. Group: Biochemicals. Grades: Purified. CAS No. 145455-35-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
L-692,585 Quick inquiry Where to buy Suppliers range | L-692,585 is a non-peptide, highly potent and selective ghrelin receptor (GHS-R1a) agonist with Ki value of 0.8 nM. It shows GH-secretory activity in several species including human. It increases plasma GH levels in vivo and is 2-2.5-fold more potent than GHRP-6. Synonyms: 3-[[(2R)-2-Hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-butanamide; [R-(R*,R*)]-3-[(2-hydroxypropyl)amino]-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-butanamide; 1H-1-Benzazepine, Butanamide derivative; L 692585; L692585; L-692585. Grades: ≥98% by HPLC. CAS No. 145455-35-2. Molecular formula: C32H37N7O3. Mole weight: 567.69. | |
L-693,403 maleate Quick inquiry Where to buy Suppliers range | L-693,403 maleate is the maleate salt of L-693,403, which is a sigma receptor-binding compound. It has excellent selectivity over the dopamine D2 receptor and belongs high affinity σ ligand. It is used for the treatment of diabetes-associated pain. Synonyms: L-693,403 maleate; L 693,403 maleate; L693,403 maleate; N-1'-Benzyl-3,4-dihydrospiro[1H-indene-1,4'-piperidine] Maleate; 2,3-Dihydro-1'-(phenylmethyl)-spiro[1H-indene-1,4'-piperidine] (Z)-2-Butenedioate. CAS No. 207455-21-8. Molecular formula: C24H27NO4. Mole weight: 393.48. | |
L-694,247 Quick inquiry Where to buy Suppliers range | L-694,247 is a highly selective and extremely potent 5-HT1D receptor agonist. Synonyms: L-694,247; L 694,247; L694,247. N-[4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide; 2-[5-[3-(4-Methylsulfonylamino)benzyl-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethanamine. Grades: ≥98% by HPLC. CAS No. 137403-12-4. Molecular formula: C20H21N5O3S. Mole weight: 411.48. | |
L-696474 Quick inquiry Where to buy Suppliers range | L-696474 is extracted from Hypoxylon fragiforme MF5511. It can competitively inhibit the action of HIV-1 protease with an IC50 of 3 μmol/L. Synonyms: L-696,474; 18-dehydroxycytochalasin H. Grades: >98% by HPLC. CAS No. 141994-72-1. Molecular formula: C30H39NO4. Mole weight: 477.63. | |
L-6-Hydroxynorleucine Quick inquiry Where to buy Suppliers range | L-6-Hydroxynorleucine. Group: Heterocyclic Organic Compound. Alternative Names: (S)-2-AMINO-6-HYDROXYHEXANOIC ACID;6-HYDROXY-L-NORLEUCINE;L-6-HYDROXYNORLEUCINE;H-NLE(6-HYDROXY)-OH;Hydroxynotleucine;(+)-L-e-Hydroxynorleucine;L-a-Amino-e-hydroxy-n-caproic Acid;L-e-Hydroxynorleucine. CAS No. 6033-32-5. Molecular formula: C6H13NO3. Mole weight: 147.17. | |
L-6-Hydroxynorleucine Quick inquiry Where to buy Suppliers range | L-6-Hydroxynorleucine. Uses: Amino Acids & Derivatives. Product ID: CP07302. | |
L-701,252 Quick inquiry Where to buy Suppliers range | L-701,252 is an antagonist at the glycine-NMDA site with IC50 value of 420 nM. It is used as a potent systemic anticonvulsant. Synonyms: L-701,252; L 701,252; L701,252; 7-Chloro-3-(cyclopropylcarbonyl)-4-hydroxy-2(1H)-quinolinone. Grades: ≥99% by HPLC. CAS No. 151057-13-5. Molecular formula: C13H10ClNO3. Mole weight: 263.68. | |
L-701,324 Quick inquiry Where to buy Suppliers range | L-701,324 is a selective antagonist at the glycine site of the NMDA glutamate receptor. L-701,324 shows a beneficial action in the animal model of parkinsonian rigidity. L-701,324 is also a anticonvulsant which has a reduced propensity to activate mesolimbic dopaminergic systems in rodents. Preclinical trials for the treatment of Anxiety disorders, Epilepsy, Major depressive disorder and Psychotic disorders were discontinued. Uses: Anxiety disorders; epilepsy; major depressive disorder; psychotic disorders. Synonyms: L701324; L 701324; L-701324; L701324; L 701324; L-701324; 7-CHLORO-4-HYDROXY-3-(3-PHENOXY)PHENYL-2(1H)-QUINOLINONE;7-CHLORO-4-HYDROXY-3-(3-PHENOXY )PHENYLQUINOLIN-2[1H]-ONE. Grades: 98 %. CAS No. 142326-59-8. Molecular formula: C21H14ClNO3. Mole weight: 363.79. | |
L-701,324 (7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone) Quick inquiry Where to buy Suppliers range | A highly potent and selective antagonist for thenMDA receptor glycine site (IC50 = 2.0nM; Kd = 28nM; ED50 = 0.9nM either intraperitoneal (ip) or oral (po) adminited). The first such compounds with significant activity in the central nervous system following oral dosing and a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 142326-59-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
L-703,606 oxalate salt hydrate Quick inquiry Where to buy Suppliers range | solid. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 351351-06-9 (anhydrous). Pack Sizes: 5MG, 25MG. Mole weight: 598.47 (anhydrous basis). Catalog: ALP351351069. | |
L-703,664 succinate Quick inquiry Where to buy Suppliers range | L-703,664 succinate is the succinate salt of L-703,664, which is a 5-HT1D receptor agonist. It shows selectivity over other 5-HT receptor subtypes and other receptors. Synonyms: L-703,664 succinate; L 703,664 succinate; L703664 succinate; N,N-Dimethyl-5-[(5-methyl-1,2,5-thiadiazolidin-2-yl)methyl]-S,S-dioxide-1H-indole-3-ethanamine Butanedioate; N,N-Dimethyl-5-[(5-methyl-1,1-dioxido-1,2,5-thiadiazolidin-2-yl)methyl]-1H-indole-3-ethanamine Butanedioate; 1H-Indole-3-ethanamine-1,2,5-thiadiazolidine Derivative; N,N-Dimethyl-5-[(5-methyl-1,1-dioxodo-1,2,5-thiadiazolidin-2-yl)methyl]-1H-indole-3-ethanamine succinate. Grades: ≥99% by HPLC. CAS No. 144776-01-2. Molecular formula: C20H30N4O6S. Mole weight: 454.54. | |
L-732,138 Quick inquiry Where to buy Suppliers range | L-732,138 is a highly selective and potent substance P (SP) receptor antagonist. It is also a potent and competitive tachykinin NK1 receptor antagonist with IC50 value of 2.3 nM. It is also approximately 200-fold more potent at human NK-1 receptors than at rat NK-1 receptors. It is approximately 1000-fold more potent at cloned human NK-1 receptors than at cloned human NK-2 and NK-3 receptors. Synonyms: 3,5-bis(TFM)Bz NAcTrp; L732138; L 732138; L-732138; L-732, 138; N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl Ester; N-Acetyltryptophan 3,5-bis(trifluoromethyl)benzyl Ester. Grades: ≥98% by HPLC. CAS No. 148451-96-1. Molecular formula: C22H18F6N2O3. Mole weight: 472.39. | |
L-733,060 Quick inquiry Where to buy Suppliers range | L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ anxiolytic agent and also show antitumor activity at some extent. Uses: Neurokinin-1 receptor antagonists. Synonyms: L-733060; L 733060; L 733061; L-733061; L 733,060; L 733,061; (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine. Grades: 98%. CAS No. 148700-85-0. Molecular formula: C20H19F6NO. Mole weight: 403.36. | |
L-733,060 hydrochloride Quick inquiry Where to buy Suppliers range | The hydrochloride salt form of L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ anxiolytic agent and also show antitumor activity at some extent. Ki: 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors, respectively. Synonyms: L-733,061 hydrochloride; MLS-002153399; L-733,060 hydrochloride; L 733,061 hydrochloride; MLS 002153399; L 733,060 hydrochloride; L733,061 hydrochloride; MLS002153399; L733,060 hydrochloride; L733061 hydrochloride; L733060 hydrochloride; (2R,3R)-3-[(3,5-bis(Trifluoromethyl)phenyl)methoxy]-2-phenylpiperidine hydrochloride; SMR001230778. Grades: 98%. CAS No. 148687-76-7. Molecular formula: C20H19F6NO.HCl. Mole weight: 439.82. | |
L-733,060 Hydrochloride Quick inquiry Where to buy Suppliers range | L-733,060 Hydrochloride. Group: Heterocyclic Organic Compound. Grades: >99 %. CAS No. 148700-85-0. Molecular formula: C20H19F6NO.HCl. Mole weight: 439.82. | |
L-741,626 Quick inquiry Where to buy Suppliers range | L-741,626 is a selective and potent D2 dopamine receptor antagonist. It is centrally active following systemic administration in vivo. It inhibits quinpirole-stimulated mitogenesis transfected with human D2 and D3 receptors in a functional assay. It reversibly blocks D2-mediated currents in Xenopus oocytes by G protein-gated inwardly rectifying K+ (GIRK) channels. It inhibits the conditioned avoidance response (CAR) in rats and apomorphine-induced climbing behavior in mice. It evokes a catalepsy response and blocks gnawing induced by methylphenidate in rat models of potential extrapyramidal activity. Uses: Dopamine antagonists. Synonyms: L-741,626; L741,626; L 741,626; 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol; 3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole; 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-ol; (±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole. Grades: ≥98% by HPLC. CAS No. 81226-60-0. Molecular formula: C20H21ClN2O. Mole weight: 340.85. | |
L-741,626 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 81226-60-0. Pack Sizes: 10MG, 50MG. Mole weight: 340.85. Catalog: AP81226600. Assay: ≥98% (HPLC). | |
L-741,626 (Dopamine D2 Receptor Antagonist, L-741,626, L-741626, L741626) Quick inquiry Where to buy Suppliers range | Selective dopamine D2 receptor antagonist that is shown to reversibly block agonist-induced activation of GIRK currents. Reported to have a 15-fold selectivity for D2R over D3R in vitro. Inhibition of 3H-spirperone binding to cloned rat Dopamine receptors show the following Ki values: D2R (7.1nM), D3R (155nM), D4R (596nM). Commonly used D2 inhibitor in addiction research. Group: Biochemicals. Grades: Highly Purified. CAS No. 81226-60-0. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences. | Worldwide |
L-741,742 hydrochloride Quick inquiry Where to buy Suppliers range | L-741,742 hydrochloride is the hydrochloride salt of L-741,742, which is a highly selective and potent D4 dopamine receptor antagonist with Ki value of 3.5 nM at cloned human D4 receptors. It is used in the treatment of psychological diseases such as schizophrenia and depression. Synonyms: L-741,742 hydrochloride; L741,742 hydrochloride; L 741,742 hydrochloride; 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole hydrochloride. Grades: ≥98% by HPLC. CAS No. 874882-93-6. Molecular formula: C23H26N2Cl2O. Mole weight: 417.38. | |
L-744832 Quick inquiry Where to buy Suppliers range | L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity. Synonyms: L 744832; L744832; (2S)-2-[[2-[(2S,3S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylpentoxy]-1-oxo-3-phenylpropyl]amino]-4-methylsulfonylbutanoic acid propan-2-yl ester. CAS No. 160141-09-3. Molecular formula: C26H45N3O6S2. Mole weight: 559.78. | |
L-744832 Quick inquiry Where to buy Suppliers range | L 744832. CAS No. 1177806-11-9. | |
L-744832 ((2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine Sulfone Isopropyl Ester Bis Hydrchloride) Quick inquiry Where to buy Suppliers range | Ras farnesyltransfer. Group: Biochemicals. Alternative Names: (2S)-[(2S)-[(2R)-Amino-3-mercapto]-propylamino-(3S)-methyl]pentyloxy-3-phenylpropionyl-methionine Sulfone Isopropyl Ester Bis Hydrchloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
L-745,870 trihydrochloride Quick inquiry Where to buy Suppliers range | L-745,870 trihydrochloride is the trihydrochloride salt of L-745,870, which is highly selective and potent D4 dopamine receptor antagonist with Ki value of 0.51nM. It is > 1000-fold selective over 5-HT2, D1 and D5 receptors. It has antipsychotic effects in animal models, but it was not effective in human trials. Synonyms: L-745,870 trihydrochloride; L 745,870 trihydrochloride; L745,870 trihydrochloride; 3-(4-[4-Chlorophenyl]piperazin-1-yl)-methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride. Grades: ≥99% by HPLC. CAS No. 866021-03-6. Molecular formula: C18H22N4Cl2. Mole weight: 436.21. | |
L-745,870 Trihydrochloride (Dopamine D4 Receptor Antagonist, L-745,870 Trihydrochloride, L-745870, L745870) Quick inquiry Where to buy Suppliers range | Selective D4 receptor antagonist with excellent brain penetration. Displays an affinity (Ki) of 0.4nM for human D4 receptors with >1000-fold binding selectivity over D2 and D3 receptors. Does not block agonist-induced activation of GIRK currents. It is used frequently in retinal and CNS studies of D4 modulation. Group: Biochemicals. Grades: Highly Purified. CAS No. 158985-00-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
L-748,337 Quick inquiry Where to buy Suppliers range | L-748,337. Group: Biochemicals. Grades: Purified. CAS No. 244192-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
L-748,337 Quick inquiry Where to buy Suppliers range | L-748,337 is a selective and competitive β3-adrenoceptor antagonist with Ki value of 4.0 nM. It can inhibit agonist-induced relaxation of smooth muscle and lipolysis in rhesus monkey adipocytes. It also inhibits cAMP accumulation in response to isoproterenol. It reduces apoptosis, iNOS expression and attenuates nitric oxide-induced cell proliferation in a melanoma cell line. Synonyms: L-748337; L 748337; L748337. N- [ [3- [ (2S) -2-Hydroxy-3- [ [2- [4- [ (phenylsulfonyl) amino] phenyl] ethyl] amino] propoxy] phenyl] methyl] -acetamide. Grades: ≥98% by HPLC. CAS No. 244192-94-7. Molecular formula: C26H31N3O5S. Mole weight: 497.61. | |
L-750,667 trihydrochloride Quick inquiry Where to buy Suppliers range | solid. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1021868-80-3. Pack Sizes: 5MG, 25MG. Mole weight: 527.66. Catalog: AP1021868803. | |
L-755,507 Quick inquiry Where to buy Suppliers range | Potent beta3-adrenergic receptor partial agonist > 1000-fold selective over beta1- and beta2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human beta3-, beta1- and beta2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). Group: Biochemicals. Alternative Names: 4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [ (2S) -2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide; (S) -4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide. Grades: Highly Purified. CAS No. 159182-43-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 584.73. US Biological Life Sciences. | Worldwide |
L-755507 Quick inquiry Where to buy Suppliers range | L-755,507 is a potent, selective and novel β3-adrenergic receptor (β3-AR) partial agonist with an EC50 value of 0.43 nM. It is over 440-fold selectivity for β3 compared to β1 and β2-adrenergic receptor binding. It has been used to enhance CRISPR-mediated homology-directed repair efficiency for large fragment insertions and for point mutations at 5 μM in human induced pluripotent stem cells. It also has been used to identify signaling pathways activated through β3-adrenergic receptors. It stimulates lipolysis in rhesus adipocytes in vitro. It may also serve as a potential therapeutic target for the treatment of type II diabetes and obesity. Synonyms: L-755507; L 755507; L755507; 4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [ (2S) -2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide; (S) -4- [ [ (Hexylamino) carbonyl] amino] -N- [4- [2- [ [2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] benzenesulfonamide; 1-Hhexyl-3- [4- [ [4- [2- [ [ (2S) -2-hydroxy-3- (4-hydroxyphenoxy) propyl] amino] ethyl] phenyl] sulfamoyl] phenyl] urea. Grades: ≥98% by HPLC. CAS No. 159182-43-1. Molecular formula: C30H40N4O6S. Mole weight: 584.73. | |
L-759,633 Quick inquiry Where to buy Suppliers range | L-759,633 is a potent cannabinoid receptor (CB2) agonist with 163-fold selectivity for CB2 over CB1. L-759,633 exhibits great potency against forskolin-stimulated cyclic AMP production in CB2-transfected cells than in CB1-transfected cells. Synonyms: (6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene. Grades: ≥98%. CAS No. 174627-50-0. Molecular formula: C26H40O2. Mole weight: 384.6. | |
L 760735 Quick inquiry Where to buy Suppliers range | L 760735. Group: Biochemicals. Grades: Purified. CAS No. 188923-01-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
L760735 Quick inquiry Where to buy Suppliers range | L760735 is a high-affinity NK1 receptor antagonist with IC50 value of 0.19 nM. It is selective over NK2 and NK3 receptors. It is used in the synthetic preparation of a (triazolylmethyl)morpholine derivative as substance P antagonist. It has anxiolytic and antidepressant-like effects and is orally active. Synonyms: L760735; L 760735; L-760735; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl-N,N-dimethyl-1H-1,2,3-triazole-4-methanamine Hydrochloride; [2R-[2α(R*),3α]]-5-[[2-[1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-N,N-dimethyl-1H-1,2,3-triazole-4-methanamine Monohydrochloride. Grades: ≥99% by HPLC. CAS No. 188923-01-5. Molecular formula: C26H29F7N5O2Cl. Mole weight: 611.98. | |
L-768242 Quick inquiry Where to buy Suppliers range | L-768242, an indole derivative, has been found to be a CB2 receptor agonist and was once studied to exhibit anti-nociceptive and antihyperalgesic activities in neuropathic and inflammatory pain models. Synonyms: L-768242; L768242; L 768242; GW-405833; GW405833. GW 405833; (2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-yl-ethyl)-indol-1-yl]-methanone; (2,3-dichlorophenyl)(5-methoxy-2-methyl-3-(2-morpholinoethyl)-1H-indol-1-yl)methanone; GW405833. Grades: 98%. CAS No. 180002-83-9. Molecular formula: C23H24Cl2N2O3. Mole weight: 483.82. | |
L-771688 Quick inquiry Where to buy Suppliers range | L-771688, also known as SNAP 6383, is a new potent and highly selective α1A-adrenoceptor antagonist with 500-fold selective over α1B and α1D-adrenoceptors. Synonyms: methyl (4S)-4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-3-[3-(4-pyridin-2-ylpiperidin-1-yl)propylcarbamoyl]-1,4-dihydropyrimidine; 5-carboxylate; L 771,688; L 771688; L-771,688; L-771688; methyl 4-(3,4-difluorophenyl)-6-((methyloxy)methyl)-2-oxo-3-((((3-(4-2-pyridinyl)-1-piperidinyl)propyl)amino)carbonyl)-1,2,3,4; tetrahydro-5-pyrimidinecarboxylate; SNAP 6383; SNAP-6383. CAS No. 200050-59-5. Molecular formula: C28H33F2N5O5. Mole weight: 557.59. | |
l 778123 Quick inquiry Where to buy Suppliers range | l 778123. Group: Heterocyclic Organic Compound. CAS No. 253863-00-2. Product ID: ACM253863002. Molecular formula: C22H21Cl2N5O. Mole weight: 442.341. | |
L-778123 Quick inquiry Where to buy Suppliers range | L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination ofL-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed. Synonyms: L778,123; L-778,123; L 778,123; L 778123; L778123; 1-(3-chlorophenyl)-4-[1-(4-cyanobenzyl)-5-imidazolyl methyl]-2-piperazinone. CAS No. 183499-57-2. Molecular formula: C22H20ClN5O. Mole weight: 405.88. |