A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
L-364,373. Group: Biochemicals. Grades: Purified. CAS No. 103342-82-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
L-364,373
L-364,373 is a KV7.1 (KCNQ1) channel activator. It decreases action potential duration (APD) in cardiac myocytes and activates the cardiac IKs current. Synonyms: 5-(2-Fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-2H-1,4-benzodiazepin-2-one; (R)-5-(2-Fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-2H-1,4-benzodiazepin-2-one; (3R)-5-(2-Fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-2H-1,4-benzodiazepin-2-one; R-L3; L 364373. Grades: ≥98% by HPLC. CAS No. 103342-82-1. Molecular formula: C25H20FN3O. Mole weight: 397.44.
L-365,260
L-365,260 is a nonpeptide cholecystokinin receptor 2 (CCK2/CCKB) antagonist. It selectively binds to gastrin and CCK2 sites to reduce basal acid secretion, and prevent gastrointestinal damage in models of peptic ulcer disease. Synonyms: N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea. Grades: ≥99% by HPLC. CAS No. 118101-09-0. Molecular formula: C24H22N4O2. Mole weight: 398.46.
L-365,260
L-365,260. Group: Biochemicals. Grades: Purified. CAS No. 118101-09-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
L-368,899 hydrochloride
L-368,899 hydrochloride is the hydrochloride salt of L-368,899, which is a non-peptide, orally active and potent oxytocin receptor antagonist with IC50 value of 8.9 nM. It displays > 40-fold selectivity over vasopressin V1a and V2 receptors. It antagonizes oxytocin-induced uterine contractions in vitro and in vivo. It may be used in the treatment of early pregnancy failure. Synonyms: L-368,899 hydrochloride; L 368,899 hydrochloride; L368,899 hydrochloride; L368899 hydrochloride; (2S) -2-Amino-N- [ (1S, 2S, 4R) -7, 7-dimethyl-1- [ [ [4- (2-methylphenyl) -1-piperazinyl]sulfonyl]methyl]bicyclo [2. 2. 1]hept-2-yl]-4- (methylsulfonyl) butanamide; 1- ( (7, 7-Dimethyl-2 (S) - (2 (S) -amino-4- (methylsulfonyl) butyramido) bicyclo[2, 2, 1]heptan-1 (S) -yl) methylsulfonyl) -4- (2-methylphenyl) piperazine hydrochloride. Grades: ≥97% by HPLC. CAS No. 160312-62-9. Molecular formula: C26H43N4O5S2Cl. Mole weight: 591.23.
L-368,899 hydrochloride
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC 50 s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160312-62-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108677.
L-368,899 hydrochloride
L-368,899 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 160312-62-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
Worldwide
L-371,257
L-371,257 is a potent and high affinity human oxytocin (OT) receptor antagonist with Ki value of 4.6 nM. It displays > 800-fold selectivity over human arginine vasopressin receptors V1a and V2. It antagonizes oxytocin-induced contractionsin in anesthetised rats following intravenous and intraduodenal administration. It also inhibits oxytocin-induced contractionsin in isolated rat uterine tissue. It decreases length of U-87MG cell projections induced by retinoic acid. It is orally active. Synonyms: L-371,257; L 371,257; L371,257; 1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one; 1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine. Grades: ≥99% by HPLC. CAS No. 162042-44-6. Molecular formula: C28H33N3O6. Mole weight: 507.59.
L-371,257
L-371,257. Group: Biochemicals. Grades: Purified. CAS No. 162042-44-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
L-371,257
L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor ( K i =19 nM) and vasopressin V1a receptor ( K i =3.7 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162042-44-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15010.
L-377202
L-377202 is a prodrug in which a peptide is covalently conjugated with the anthracycline antineoplastic antibiotic doxorubicin. This complex is hydrolyzed by the enzyme prostate-specific antigen (PSA), resulting in the formation of doxorubicin and leucine-doxorubicin. Selective targeting of these drugs to prostate tumor cells occurs because the hydrolyzing PSA enzyme is localized to the prostate gland. Doxorubicin and leucine-doxorubicin intercalate into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. These agents also produce toxic free-radical intermediates and interact with cell membrane lipids causing lipid peroxidation. Synonyms: L 377202; L377202; L-377,202; L 377,202; L377,202; (8S,10S)-10-[[3-[[1-(4-Carboxybutyryl)-t4Hyp-Ala-Ser-[(S)-2-cyclohexyl-Gly-]Gln-Ser-Leu-]amino]-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl]oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione. CAS No. 207395-85-5. Molecular formula: C65H89N9O25. Mole weight: 1396.46.
L-3-Amino methyl phenylalanine
L-3-Amino methyl phenylalanine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-3-[3- (aminomethyl) phenyl]propanoic acid. Grades: Highly Purified. CAS No. 57213-47-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
L-3-Amino methyl phenylalanine 98+%
L-3-Amino methyl phenylalanine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
L-3-Carbamoylphenylalanine
L-3-Carbamoyl phenyl alanine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-3- (3-carbamoylphenyl) propanoic acid. Grades: Highly Purified. CAS No. 1217651-22-3. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
L-3-Carbamoylphenylalanine 99+%
L-3-Carbamoylphenylalanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
A cell-permeable pyrrolidinyl-piperidinyl-benzamide that effectively competes against H4K20Me2 peptide for L3MBTL3 binding by targeting the first two L3MBTL3 MBT domains (Kd = 120nM in binding studies using recombinant 3MBT fragment), while exhibiting much reduced potency against L3MBTL1-H4K20Me1, 53BP1-H4K20Me2, MBTD1-H4K20Me1, or L3MBTL4-H2AK36Me1 interaction (IC50 ≥2uM; [peptide] = 150nM). Shown to increase GFP-L3MBTL fusion nucleus mobility (10nM to 1uM) in HEK293 transfectants. X-ray structural analysis reveals two 3MBT are bridged together by two UNC1215 molecules in a reciprocal fashion. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Heterocyclic Organic Compound. CAS No. 1226919-57-8. Molecular formula: C9H7D5NO3. Mole weight: 186.22. Purity: 98 atom % D. Catalog: ACM1226919578.
L-4-Oxalysine hydrochloride
L-4-oxalysine is a natural product isolated from a new species of Streptomyces roseoÍiridofuscus n.sp. in China. L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma. Synonyms: (2S)-2-amino-3-(2-aminoethoxy)propanoic acid;hydrochloride. CAS No. 118021-35-5. Molecular formula: C5H13ClN2O3. Mole weight: 184.62.
L-4-Thiazolidinecarboxylic acid
L-4-Thiazolidinecarboxylic acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: L-Thiaproline. CAS No. 34592-47-7. Molecular Formula: C4H7NO2S. Mole Weight: 133.17. Catalog: APB34592477.
Found to act on the cell membrane of tumor cells, possible causing a reverse transformation to normal cells through restoration of contact inhibition. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
L-5 Hydroxytryptophan
L-5 Hydroxytryptophan.
CA, FL & NJ
L-5-Hydroxytryptophan
L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist [1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: L-5-HTP; Oxitriptan. CAS No. 4350-9-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1716.
L-5-Hydroxytryptophan (Standard)
L-5-Hydroxytryptophan (Standard) is the analytical standard of L-5-Hydroxytryptophan. This product is intended for research and analytical applications. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist [1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: L-5-HTP (Standard); Oxitriptan (Standard). CAS No. 4350-9-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1716R.
L5K5W6
L5K5W6 is a synthetic antibacterial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Lys-Lys-Leu-Leu-Lys-Trp-Leu-Lys-Lys-Leu-Leu-NH2. Grades: 96.3%. Molecular formula: C71H128N18O11. Mole weight: 1409.92.
L-5-Methyltetrahydrofolate calcium
L-5-Methyltetrahydrofolate calcium. Group: Biochemicals. Alternative Names: Calcium levomefolate; N-[4-[[ (2-Amino-1, 4, 5, 6, 7, 8-hexahydro-5-methyl-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic acid calcium salt. Grades: Highly Purified. CAS No. 151533-22-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C20H23N7O6·Ca. US Biological Life Sciences.
Worldwide
L-5-Methyltetrahydrofolate Calcium
L-5-Methyltetrahydrofolate Calcium. CAS No. 151533-2-1. Categories: levomefolate calcium; 151533-22-1.
CA, FL & NJ
L-5-methyluridine
L-5-Methyluridine is a nucleoside analogue employed, serving as a potent therapeutic compound against afflictions caused by viral compounds, including hepatitis B and hepatitis C. It operates by impeding viral replication mechanisms, thereby exhibiting remarkable antiviral prowess. This specific product holds immense potential for application within the realms of antiviral drug investigation, as well as the examination of nucleoside metabolism intricacies and nucleic acid synthesis processes. Synonyms: beta-L-ribofuranosyl thymine; 5-methyl-1-(beta-L-ribofuranosyl)uracil; L-5-Me-rU; 1-beta-l-ribofuranosylthymine; 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-beta-L-ribofuranosyl-; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; L-5-Me-Uridine. Grades: ≥97% by HPLC. CAS No. 642082-80-2. Molecular formula: C10H14N2O6. Mole weight: 258.23.
L-[6-13C]idose
Isotope-labeled Carbohydrates13C Labeled Compounds. Alternative Names: L-idose-6-13C. CAS No. 115973-80-3. Molecular formula: 13CC5H12O6. Mole weight: 181.15. Catalog: ACM115973803.
L-651,582
L-651,582 is a novel inhibitor of both cAMP-phosphodiesterases and GMP-phosphodiesterases. It is also an orally active calcium channel blocker. It prevents oxidative phosphorylation in cancer cells and exhibits inhibition of pro-inflammatory cytokines in tumor associated macrophages. It may be used as a potential anti-cancer drug. It ameliorates experimental colitis by inhibiting nuclear factor-κB activation, colonic fibrosis and cytokine production. It has antimetastatic, antiangiogenic and antiproliferative activity in vivo. It displays selectivity towards numerous mismatch repair-deficient tumor cell lines in vitro. It blocks intracellular and mitochondrial calcium entry and flux, resulting in inhibition of calcium-release-activated calcium channel (CRAC) function, cell proliferation and maintenance of mitochondrial membrane potential. Synonyms: Carboxyamidotriazole; CAI; RFE-007; NSC-609974; L-651582; RFE007; NSC609974; L651582; 5-Amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]-1H-1,2,3-triazole-4-carboxamide. Grades: ≥98% by HPLC. CAS No. 99519-84-3. Molecular formula: C17H12Cl3N5O2. Mole weight: 424.67.
L-651,582
L-651,582. Group: Biochemicals. Grades: Purified. CAS No. 99519-84-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
L-655,240
L-655,240 is a potent and selective antagonist of thromboxane and prostaglandin endoperoxide receptor. It also blocks TP-mediated bronchoconstriction in vivo and platelet aggregation ex vivo. Synonyms: 3-(1-(4-Chlorobenzyl)-5-fluoro-3-methylindol-2-yl)-2,2-dimethylpropanoic acid. Grades: ≥98%. CAS No. 103253-15-2. Molecular formula: C21H21ClFNO2. Mole weight: 373.9.
L-655,240
L-655,240. Group: Biochemicals. Grades: Purified. CAS No. 103253-15-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
L-655708
L-655708 is a potent α5 subunit-selective GABAA receptor inverse agonist ( K i =0.45 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 130477-52-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14426.
L-655,708
L-655,708, an inverse agonist of α5 subunit involved in GABAA receptor, has been found to exhibit cognitive performance improvement in biological studies. Uses: L-655,708, is an inverse agonist of α5 subunit involved in gabaa receptor and has been found to exhibit cognitive performance improvement in biological studies. Synonyms: L-655708; L655708; L 655708; L-655,708; L655,708; L 655,708; FG-8094; FG 8094; FG8094; ETHYL (S)-11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLATE;L-655,708;11,12,13,13A-TETRAHYDRO-7-METHOXY-9-OXO-9H-IMIDAZO[1,5-A]PYRROLO[2,1-C][1,4]BENZODIAZEPINE-1-CARBOXYLIC ACID, ETHYL ESTER;11,12,1. Grades: >99 %. CAS No. 130477-52-0. Molecular formula: C18H19N3O4. Mole weight: 341.36.
L-655,708
L-655,708. Group: Biochemicals. Grades: Purified. CAS No. 130477-52-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
L 656224
L 656224 is a 5-lipoxygenase (5-LO) inhibitor. Synonyms: L-656224. Grades: ≥98% by HPLC. CAS No. 102612-16-8. Molecular formula: C20H21ClO3. Mole weight: 344.8.
L-659,877 Synthetic >98% nk2 tachykinin recept
Heterocyclic Organic Compound. Alternative Names: Cyclo(gln-trp-phe-gly-leu-met), CID164213, L 659877, L-659877, L 659,877, L-659,877, Cyclo(L-glutaminyl-L-tryptophyl-L-phenylalanylglycl-L-leucyl-L-methionyl), 125989-12-0. CAS No. 125989-12-0. Molecular formula: C38H50N8O7S. Mole weight: 762.92. Purity: 0.96. IUPACName: 3-[(2S,8S,14S,17S)-8-benzyl-5-(1H-indol-3-ylmethyl)-14-(2-methylpropyl)-17-(2-methylsulfanylethyl)-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexazacyclooctadec-2-yl]propanamide. Catalog: ACM125989120.
L67
L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC50 values of 10 μM and 10 μM.). Synonyms: L67; L-67; L 67. Grades: 98%. CAS No. 325970-71-6. Molecular formula: C16H14Br2N4O4. Mole weight: 486.12.
L67
L67 (DNA Ligase Inhibitor) is a competitive DNA ligase inhibitor that effectively inhibits DNA ligases I/III (both IC 50 are 10 μM). L67 can cause nuclear DNA damage by reducing levels of mitochondrial DNA and increasing levels of mitochondrially-generated ROS. L67 also activates the Caspase 1 -dependent apoptosis pathway in cancer cells, can be used in cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNA Ligase Inhibitor. CAS No. 325970-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15586.
L-670,596
L-670,596. Group: Biochemicals. Grades: Purified. CAS No. 121083-05-4. Pack Sizes: 10mg. US Biological Life Sciences.