A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Lombartinib impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H15ClN2O4. Mole Weight: 358.78. Catalog: APB10691.
Lombartinib impurity 6
Lombartinib impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H15ClN2O4. Mole Weight: 358.78. Catalog: APB10693.
Lombazole
Lombazole is used as an antimicrobial agent of the imidazole class. Uses: Lombazole is used as an antimicrobial agent of the imidazole class. Synonyms: Bay h 6020; Lombazolum; Lombazol; 1-([1,1'-biphenyl]-4-yl(2-chlorophenyl)methyl)-1H-imidazole; (2-Chlorophenyl)-imidazol-1-yl-(biphenyl-4-yl)methane. Grades: 98%. CAS No. 60628-98-0. Molecular formula: C22H17ClN2. Mole weight: 344.84.
lombricine kinase
Also acts on methylated lombricines such as thalassemine; the specificity varies with the source species. Group: Enzymes. Enzyme Commission Number: EC 2.7.3.5. CAS No. 9026-53-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3185; lombricine kinase; EC 2.7.3.5; 9026-53-3. Cat No: EXWM-3185.
Lomefloxacin
Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms, which is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used as a pre-operative prophylactic to prevent urinary tract infection caused by S. pneumoniae, H. influenzae, S. aureus, P. aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E. coli, and K. pneumoniae. It is used to induce genomic instability in mice1 and modification of the kinetics of growth of Gram-negative bacteria. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. Uses: Anti-bacterial agents. Synonyms: Maxaquin; SC47111A. Grades: >98%. CAS No. 98079-51-7. Molecular formula: C17H19F2N3O3. Mole weight: 351.35.
Lomefloxacin·HCl 99+% (HPLC)
Lomefloxacin·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Lomefloxacin hydrochloride
Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic , with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC47111A hydrochloride. CAS No. 98079-52-8. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0455.
Lomefloxacin hydrochloride
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C17H19F2N3O3 · HCl. CAS No. 98079-51-7. Prepack ID 39370200-1g. Molecular Weight 387.81. See USA prepack pricing.
Lomefloxacin, Hydrochloride
Fluorinated quinolone antibacterial. DNA gyrase antagonist. Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic. Lomefloxacin is an orally bioavailable, broad-spectrum fluoroquinolone antibiotic.1 In vitro, it inhibits growth of N. gonorrhoeae, E. coli, K. pneumoniae, P. vulgaris, S. epidermidis, and M. morganii (MIC90s = 0.1, 0.39, 0.39, 0.39, 0.39, and 0.78ug/ml, respectively). It also inhibits growth of S. aureus and methicillin-resistant S. aureus (MRSA; MIC90 = 3.13ug/ml for both) and of H. influenzae and ampicillin-resistant H. influenzae (MIC90 = 0.1ug/ml for both). In vivo, lomefloxacin inhibits the growth of P. mirabilis, E. coli, K. pneumoniae, and S. aureus (ED50s = 1.39, 1.45, 1.78, and 6.66mg/kg, respectively) in mouse models of systemic infection. It inhibits bacterial DNA gyrase, thereby inhibiting DNA synthesis and bacterial growth.2 Formulations containing lomefloxacin have been used in the treatment of bronchitis and urinary tr Group: Biochemicals. Alternative Names: 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Alkaflox; Bareon; Chimono; Lomebact; Lomef 400; Lomflox; Lomitas; Lomoxin; Maxaquin; Mazaquin; NY 198; Orchacin; SC 47111; Uniquin. Grades: Highly Purified. CAS No. 98079-52-8. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C17H20ClF2N3O3, Molecular Weight: 387.81. US Biological Life Sciences.
Worldwide
Lomeguatrib
Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts. Group: Biochemicals. Alternative Names: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy]-1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2. Grades: Highly Purified. CAS No. 192441-08-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Lomeguatrib
Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment. Synonyms: PaTrin 2; PaTrin2; PaTrin-2; Lomeguatrib; Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine. CAS No. 192441-08-0. Molecular formula: C10H8BrN5OS. Mole weight: 326.172.
Lomerizine
Heterocyclic Organic Compound. CAS No. 101477-56-9. Catalog: ACM101477569.
Lomerizine dihydrochloride
Lomerizine dihydrochloride is an antagonist of L- and T-type voltagegated calcium channels. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB-2796. CAS No. 101477-54-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-B0768A.
Lomerizine dihydrochloride
This product is a diphenylpiperazine calcium channel blocker with selective cerebral vasodilation. Synonyms: 1- (4, 4'-Difluorobenzhydryl) -4- (2, 3, 4-trimethoxybenzyl) piperazine·dihydrochloride; Flometizinehydrochloride; Lomerizinedihydrochloride, 99%, anewL-andT-typecalciumchannelblocker; Lomerizine2HCl; KB-2796dihydrochlorideChemicalbook; Piperazine, 1-[bis (4-fluorophenyl) methyl]-4-[ (2, 3, 4-trimethoxyphenyl) methyl]-, hydrochloride (1: 2) ; Lomerizinedihydrochloride, >=99%; 1- (Bis (4-fluorophenyl) methyl) -4- (2, 3, 4-trimethoxybenzyl) piperazinedihydrochloride. CAS No. 101477-54-7. Product ID: PAP-0072. Molecular formula: C27H32Cl2F2N2O3. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Lomerizine dihydrochloride; PAP-0072; Cardiovascular; C27H32Cl2F2N2O3; 101477-54-7. Appearance: white to tan. Standard: CP. Chemical Name: 1- (4, 4'-Difluorobenzhydryl) -4- (2, 3, 4-trimethoxybenzyl) piperazine·dihydrochloride. Grade: Pharmaceutical Grade. Solubility: DMSO: ≥30mg/mL. Storage: Inert atmosphere,2-8°C. Product Description: This product is a diphenylpiperazine calcium channel blocker with selective cerebral vasodilation.
Lomerizine Dihydrochloride
Lomerizine dihydrochloride, an L- and T-type voltagegated calcium channel blocker, is a selective cerebral vasodilator and antimigraine. Uses: Calcium channel blockers. Synonyms: KB-2796; 1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride; Terranas; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2); KB 2796; KB2796. Grades: >98%. CAS No. 101477-54-7. Molecular formula: C27H30F2N2O3.2HCl. Mole weight: 541.46.
Lometraline, an aminotetralin derivative, is a potential antidepressant and/or anxiolytic agent. Uses: A potential antidepressant and/or anxiolytic agent. Synonyms: 8-chloro-5-methoxy-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride. Grades: ≥98%. CAS No. 34552-78-8. Molecular formula: C13H19Cl2NO. Mole weight: 276.20.
Lometrexol
Lometrexol is a folate analog antimetabolite with antineoplastic activity. As the 6R diastereomer of 5,10-dideazatetrahydrofolate, lometrexol inhibits glycinamide ribonucleotide formyltransferase (GARFT), the enzyme that catalyzes the first step in the de novo purine biosynthetic pathway, thereby inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation. The agent has been shown to be active against tumors that are resistant to the folate antagonist methotrexate. Uses: Antimetabolites, antineoplastic. Synonyms: Lometrexol; LMTX; LY 264618; LY-264618; LY264618. CAS No. 106400-81-1. Molecular formula: C21H25N5O6. Mole weight: 443.46.
Lometrexol is a folate analog antimetabolite with antineoplastic activity. Synonyms: LY 264618 disodium; LY264618 disodium; NSC-722969; NSC 722969; L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-, disodium salt. Grades: 98%. CAS No. 120408-07-3. Molecular formula: C21H23N5Na2O6. Mole weight: 487.42.
Lomibuvir
Lomibuvir is an nonnucleoside NS5B polymerase inhibitor. It inhibits the 1b/Con1 HCV subgenomic replicon. It binds to the HCV polymerase with dissociation constants of 17 nM. It demonstrated effective antiviral efficacy and may be used for the treatment of HCV. It was developed by ViroChem Pharma, which was acquired by Vertex Pharmaceuticals in 2009. It is in clinical phase 2 with no progress. Uses: Lomibuvir demonstrated effective antiviral efficacy and may be used for the treatment of hcv. Synonyms: 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-; 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid; 5- (3, 3-Dimethyl-1-butynyl) -3-[ (trans-4-hydroxycyclohexyl) [ (trans-4-methylcyclohexyl) carbonyl]amino]thiophene-2-carboxylic acid; VCH 222; VX 222. Grades: >98 %. CAS No. 1026785-55-6. Molecular formula: C25H35NO4S. Mole weight: 445.62.
Lomifylline
Lomifylline is a derivative of Xanthine (HY-W017389). Lomifylline can be used in research of sepsis and septic or endotoxic shock, when combined with an antibody to TNF or a TNF binding fragment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10226-54-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114531.
Lomifylline
Heterocyclic Organic Compound. Alternative Names: LOMIFYLLINE;3,7-Dihydro-1,3-dimethyl-7-(5-oxohexyl)-1H-pmfine-2,6-dione;Cervilane;Lomifilline;3,7-Dihydro-1,3-dimethyl-7-(5-oxohexyl)-1H-purine-2,6-dione. CAS No. 10226-54-7. Molecular formula: C13H18N4O3. Mole weight: 278.31. Catalog: ACM10226547.
Lomitapide
Lomitapide (AEGR-733; BMS-201038) is a potent inhibitor of microsomal triglyceride-transfer protein ( MTP ) with an IC 50 of 8 nM in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEGR-733; BMS-201038. CAS No. 182431-12-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14667.
Lomitapide
Lomitapide. Group: Biochemicals. Alternative Names: N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide; AEGR 733; BMS 201038; BMS 201038-01; BMS 201238. Grades: Highly Purified. CAS No. 182431-12-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C39H37F6N3O2, Molecular Weight: 693.72. US Biological Life Sciences.
Worldwide
Lomitapide
Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Uses: The treatment of familial hypercholesterolemia. Synonyms: Juxtapid; Lojuxta; AEGR 733; AEGR-733; AEGR733; BMS-201038. Grades: > 98%. CAS No. 182431-12-5. Molecular formula: C39H37F6N3O2. Mole weight: 693.734.
Lomitapide Impurity 1
Lomitapide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 182439-11-8. Molecular Formula: C20H18F3NO3. Mole Weight: 377.36. Catalog: APB182439118.
Lomitapide mesylate
Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEGR-733 mesylate; BMS-201038 mesylate. CAS No. 202914-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14668.
Lomitapide Mesylate
Lomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Synonyms: Lomitapide mesylate; 202914-84-9; BMS 201038-04; Juxtapid; Lomitapide (mesylate). Grades: >98%. CAS No. 202914-84-9. Molecular formula: C40H41F6N3O5S. Mole weight: 789.83.
L-Omithine HCL
L-ornithine hydrochloride is an important basic raw material in pharmaceutical industry, an important metabolite in cells, and plays an important regulatory role in the elimination of liquid ammonia in living organisms. Synonyms: L-ORNITHINE HYDROCHLORIDE SALT;L-(+)-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE-OH HCL;L-ORNITHINE-OH HYDROCHLORIDE;L-ORN HCL;L-ORNITHINE HCL;L(+)-ORNITHINE HYDROCHLORIDE. CAS No. 3184-13-2. Product ID: PAP-0030. Molecular formula: C5H13ClN2O2. Category: Amino acid. Product Keywords: Amino Acid Series; L-Omithine HCL; PAP-0030; Amino acid; C5H13ClN2O2; 3184-13-2. Appearance: at 100.00 %. mild green bark. Chemical Name: L(+)-Ornithine hydrochloride. Grade: Pharmaceutical Grade. Solubility: H2O: 100 mg/mL. Storage: Keep in dark place,Inert atmosphere,Room temperature. Applications: L-ornithine hydrochloride has the effect of treating liver cirrhosis, enhancing human immunity and resisting fatigue. Melting Point: 245 °C (dec.)(lit.). Density: 1.57. Product Description: L-ornithine hydrochloride is an important basic raw material in pharmaceutical industry, an important metabolite in cells, and plays an important regulatory role in the elimination of liquid ammonia in living organisms.
Lomofungin
It is produced by the strain of Str. lomondensis var. lomondensis NRRL 3252. It is an antibiotic of the phenazine derivatives. It has anti-bacterial and fungal effects, but the anti-bacterial effects are weak. Synonyms: Lomondomycin; NSC 106995; NSC 156939; U-24792; 1-carbomethoxy-5-formyl-4,6,8-trihydroxyphenazine; 6-Formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid methyl ester. Grades: >95%. CAS No. 26786-84-5. Molecular formula: C15H10N2O6. Mole weight: 314.25.
Lomustine
Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCNU; NSC 79037. CAS No. 13010-47-4. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-13669.
Lomustine
Lomustine (420 μM) triggers apoptosis through the mitochondrial pathway via decrease in the level of the anti-apoptosis proteins Bcl-2 and Bcl-xl, respectively. Uses: Antineoplastic agents, alkylating. Synonyms: nsc79037; nsc 79037; nsc-79037. Grades: >98%. CAS No. 13010-47-4. Molecular formula: C9H16ClN3O2. Mole weight: 233.7.
Lomustine
250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H16ClN3O2. CAS No. 13010-47-4. Prepack ID 89981121-250mg. Molecular Weight 233.7. See USA prepack pricing.
Lomustine
Chloroethylnitrosourea derivative with antitumor activity. Similar to carmustine, chlorozotocin, nimustine, ranimustine. Antineoplastic. Group: Biochemicals. Alternative Names: N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea. Grades: Highly Purified. CAS No. 13010-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Lomustine EP impurity C
Lomustine EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2387-23-7. Molecular Formula: C13H24N2O. Mole Weight: 224.34. Catalog: APB2387237.
Lonafarnib
Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras , K-ras and N-ras with IC 50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch66336. CAS No. 193275-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15136.
Lonafarnib
Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. Uses: Enzyme inhibitors. Synonyms: SCH 66336; SCH-66336; SCH66336; Sarasar. Grades: > 95%. CAS No. 193275-84-2. Molecular formula: C27H31Br2ClN4O2. Mole weight: 638.829.
Lonafarnib
Lonafarnib. Group: Biochemicals. Alternative Names: 4-[2-[4-[(11R)-3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide; Sarasar; Sch 66336. Grades: Highly Purified. CAS No. 193275-84-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H31Br2ClN4O2. US Biological Life Sciences.
Worldwide
Lonaprisan
Cas No. 211254-73-8.
Lonazolac
Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53808-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-W173309.
Loncastuximab
Loncastuximab (RB4v1.2) is an anti- CD19 monoclonal antibody. Loncastuximab shows antitumor activity and has potential application in non-Hodgkin's lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RB4v1.2. CAS No. 1875032-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99711.
Loncastuximab tesirine
Loncastuximab tesirine is a human cluster of differentiation 19 ( CD19 )-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis , it can be used for the research of diffuse large B-cell lymphoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Loncastuximab tesirine-lpyl; ADCT-402. CAS No. 1879918-31-6. Pack Sizes: 100 μg; 200 μg; 500 μg; 1 mg. Product ID: HY-P99349.
long-chain-3-hydroxyacyl-CoA dehydrogenase
This enzyme was purified from the mitochondrial inner membrane. The enzyme has a preference for long-chain substrates, and activity with a C16 substrate was 6- to 15-fold higher than with a C4 substrate (cf. EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase). Group: Enzymes. Synonyms: β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD. Enzyme Commission Number: EC 1.1.1.211. CAS No. 84177-52-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0116; long-chain-3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.211; 84177-52-6; β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD. Cat No: EXWM-0116.
long-chain acyl-[acyl-carrier-protein] reductase
Catalyses the reaction in the opposite direction. This enzyme, purified from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the NAD(P)H-dependent reduction of an activated fatty acid (acyl-[acp]) to the corresponding aldehyde. Together with EC 4.1.99.5, octadecanal decarbonylase, it is involved in alkane biosynthesis. The natural substrates of the enzyme are C16 and C18 activated fatty acids. Requires Mg2+. Group: Enzymes. Synonyms: long-chain acyl-[acp] reductase; fatty acyl-[acyl-carrier-protein] reductase; acyl-[acp] reductase. Enzyme Commission Number: EC 1.2.1.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1183; long-chain acyl-[acyl-carrier-protein] reductase; EC 1.2.1.80; long-chain acyl-[acp] reductase; fatty acyl-[acyl-carrier-protein] reductase; acyl-[acp] reductase. Cat No: EXWM-1183.
long-chain acyl-CoA dehydrogenase
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids β-oxidation. The enzyme from pig liver can accept substrates with acyl chain lengths of 6 to at least 16 carbon atoms. The highest activity was found with C12, and the rates with C8 and C16 were 80 and 70%, respectively. The enzyme from rat can accept substrates with C8-C22. It is most active with C14 and C16, and has no activity with C4, C6 or C24. cf. EC 1.3.8.1, short-chain acyl-CoA dehydrogenase, EC 1.3.8.8, medium-chain acyl-CoA dehydrogenase, and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase. Group: Enzymes. Synonyms: palmitoyl-CoA dehydrogenase; palmitoyl-coenzyme A dehydrogenase; long-chain acyl-coenzyme A dehydrogenase; long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase; ACADL (gene name). Enzyme Commission Number: EC 1.3.8.8. CAS No. 59536-74-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1415; long-chain acyl-CoA dehydrogenase; EC 1.3.8.8; 59536-74-2; palmitoyl-CoA dehydrogenase; palmitoyl-coenzyme A dehydrogenase; long-chain acyl-coenzyme A dehydrogenase; long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase; ACADL (gene name). Cat No: EXWM-1415.
long-chain acyl-CoA ω-monooxygenase
The enzymes from solanaceous plants are involved in the biosynthesis of stigmatic estolide, a lipid-based polyester that forms a major component of the exudate. Group: Enzymes. Synonyms: long-chain acyl-CoA ω-hydroxylase; CYP86A22 (gene name); CYP52M1 (gene name). Enzyme Commission Number: EC 1.14.13.204. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0806; long-chain acyl-CoA ω-monooxygenase; EC 1.14.13.204; long-chain acyl-CoA ω-hydroxylase; CYP86A22 (gene name); CYP52M1 (gene name). Cat No: EXWM-0806.
long-chain acyl-protein thioester reductase
Together with a hydrolase component (EC 3.1.2.2 and EC 3.1.2.14) and a synthetase component (EC 6.2.1.19), this enzyme forms a multienzyme fatty acid reductase complex that produces the long-chain aldehyde substrate of the bacterial luciferase enzyme (EC 1.14.14.3). The enzyme is acylated by receiving an acyl group from EC 6.2.1.19, and catalyses the reduction of the acyl group, releasing the aldehyde product. The enzyme is also able to accept the acyl group from a long-chain acyl-CoA. Group: Enzymes. Synonyms: luxC (gene name); acyl-CoA reductase; acyl coenzyme A reductase; long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); long-chain-fatty-acyl-CoA reductase. Enzyme Commission Number: EC 1.2.1.50. CAS No. 50936-56-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1154; long-chain acyl-protein thioester reductase; EC 1.2.1.50; 50936-56-6; luxC (gene name); acyl-CoA reductase; acyl coenzyme A reductase; long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); long-chain-fatty-acyl-CoA reductase. Cat No: EXWM-1154.
long-chain-alcohol dehydrogenase
Hexadecanol is a good substrate. Group: Enzymes. Synonyms: long-chain alcohol dehydrogenase; fatty alcohol oxidoreductase. Enzyme Commission Number: EC 1.1.1.192. CAS No. 76774-36-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0095; long-chain-alcohol dehydrogenase; EC 1.1.1.192; 76774-36-2; long-chain alcohol dehydrogenase; fatty alcohol oxidoreductase. Cat No: EXWM-0095.
long-chain-alcohol O-fatty-acyltransferase
Transfers saturated or unsaturated acyl residues of chain-length C18 to C20 to long-chain alcohols, forming waxes. The best acceptor is cis-icos-11-en-1-ol. Group: Enzymes. Synonyms: wax synthase; wax-ester synthase. Enzyme Commission Number: EC 2.3.1.75. CAS No. 64060-40-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2255; long-chain-alcohol O-fatty-acyltransferase; EC 2.3.1.75; 64060-40-8; wax synthase; wax-ester synthase. Cat No: EXWM-2255.
long-chain-alcohol oxidase
Oxidizes long-chain fatty alcohols; best substrate is dodecyl alcohol. Group: Enzymes. Synonyms: long-chain fatty alcohol oxidase; fatty alcohol oxidase; fatty alcohol:oxygen oxidoreductase; long-chain fatty acid oxidase. Enzyme Commission Number: EC 1.1.3.20. CAS No. 129430-50-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0402; long-chain-alcohol oxidase; EC 1.1.3.20; 129430-50-8; long-chain fatty alcohol oxidase; fatty alcohol oxidase; fatty alcohol:oxygen oxidoreductase; long-chain fatty acid oxidase. Cat No: EXWM-0402.
long-chain-aldehyde dehydrogenase
The best substrate is dodecylaldehyde. Group: Enzymes. Synonyms: long-chain aliphatic aldehyde dehydrogenase; long-chain fatty aldehyde dehydrogenase; fatty aldehyde:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.2.1.48. CAS No. 59298-89-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1151; long-chain-aldehyde dehydrogenase; EC 1.2.1.48; 59298-89-4; long-chain aliphatic aldehyde dehydrogenase; long-chain fatty aldehyde dehydrogenase; fatty aldehyde:NAD+ oxidoreductase. Cat No: EXWM-1151.
long-chain alkane monooxygenase
The enzyme, characterized from the bacterium Geobacillus thermodenitrificans NG80-2, is capable of converting alkanes ranging from C15 to C36 into their corresponding primary alcohols. The FMNH2 cofactor is provided by an FMN reductase. Group: Enzymes. Enzyme Commission Number: EC 1.14.14.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0925; long-chain alkane monooxygenase; EC 1.14.14.28. Cat No: EXWM-0925.
long-chain-enoyl-CoA hydratase
Acts in the reverse direction. The best substrate is oct-3-enoyl-CoA. Unlike EC 4.2.1.17 enoyl-CoA hydratase, it does not act on crotonoyl-CoA. Group: Enzymes. Synonyms: long-chain enoyl coenzyme A hydratase. Enzyme Commission Number: EC 4.2.1.74. CAS No. 62009-81-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5058; long-chain-enoyl-CoA hydratase; EC 4.2.1.74; 62009-81-8; long-chain enoyl coenzyme A hydratase. Cat No: EXWM-5058.
The enzyme ligates long chain fatty acids (with aliphatic chain of 13-22 carbons) to an acyl-carrier protein. Not identical with EC 6.2.1.3 long-chain-fatty-acid-CoA ligase. Group: Enzymes. Synonyms: acyl-[acyl-carrier-protein] synthetase (ambiguous); acyl-ACP synthetase (ambiguous); stearoyl-ACP synthetase; acyl-acyl carrier protein synthetase (ambiguous); long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming). Enzyme Commission Number: EC 6.2.1.20. CAS No. 77322-37-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5679; long-chain-fatty-acid-[acyl-carrier-protein] ligase; EC 6.2.1.20; 77322-37-3; acyl-[acyl-carrier-protein] synthetase (ambiguous); acyl-ACP synthetase (ambiguous); stearoyl-ACP synthetase; acyl-acyl carrier protein synthetase (ambiguous); long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming). Cat No: EXWM-5679.
long-chain-fatty-acid-CoA ligase
Acts on a wide range of long-chain saturated and unsaturated fatty acids, but the enzymes from different tissues show some variation in specificity. The liver enzyme acts on acids from C6 to C20; that from brain shows high activity up to C24. Group: Enzymes. Synonyms: acyl-CoA synthetase; fatty acid thiokinase (long chain); acyl-activating enzyme; palmitoyl-CoA synthase; lignoceroyl-Co. Enzyme Commission Number: EC 6.2.1.3. CAS No. 9013-18-7. ACS3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5687; long-chain-fatty-acid-CoA ligase; EC 6.2.1.3; 9013-18-7; acyl-CoA synthetase; fatty acid thiokinase (long chain); acyl-activating enzyme; palmitoyl-CoA synthase; lignoceroyl-CoA synthase; arachidonyl-CoA synthetase; acyl coenzyme A synthetase; acyl-CoA ligase; palmitoyl coenzyme A synthetase; thiokinase; palmitoyl-CoA ligase; acyl-coenzyme A ligase; fatty acid CoA ligase; long-chain fatty acyl coenzyme A synthetase; oleoyl-CoA synthetase; stearoyl-CoA synthetase; long chain fatty acyl-CoA synthetase; long-chain acyl CoA synthetase; fatty acid elongase; LCFA synthetase; pristanoyl-CoA synthetase; ACS3; long-chain acyl-CoA synthetase I; long-chain acyl-CoA synthetase II; fatty acyl-coenzyme A synthetase; long-chain acyl-coenzyme A synthetase; FAA1. Cat No: EXWM-5687.
long-chain fatty acid ω-monooxygenase
The plant enzyme CYP704B1, which is involved in the synthesis of sporopollenin, a complex polymer found at the outer layer of spores and pollen, acts on palmitate (18:0), stearate (18:0) and oleate (18:1). The plant enzyme CYP86A1 also acts on laurate (12:0). The enzyme from the yeast Starmerella bombicola (CYP52M1) acts on C16 to C20 saturated and unsaturated fatty acids and can also hydroxylate the (ω-1) position. The mammalian enzyme CYP4A acts on laurate (12:0), myristate (14:0), palmitate (16:0), oleate (18:1), and arachidonate (20:4). Group: Enzymes. Synonyms: CYP704B1 (gene name); CYP52M1 (gene name); CYP4A (gene name); CYP86A (gene name). Enzyme Commission Number: EC 1.14.13.205. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0807; long-chain fatty acid ω-monooxygenase; EC 1.14.13.205; CYP704B1 (gene name); CYP52M1 (gene name); CYP4A (gene name); CYP86A (gene name). Cat No: EXWM-0807.
long-chain-fatty-acid-protein ligase
Together with a hydrolase component (EC 3.1.2.2/EC 3.1.2.14) and a reductase component (EC 1.2.1.50), this enzyme forms a multienzyme fatty acid reductase complex that produces the long-chain aldehyde substrate of the bacterial luciferase enzyme (EC 1.14.14.3). The enzyme activates free long-chain fatty acids, generated by the action of the transferase component, forming a fatty acyl-AMP intermediate, followed by the transfer of the acyl group to an internal L-cysteine residue. It then transfers the acyl group to EC 1.2.1.50, long-chain acyl-protein thioester reductase. Group: Enzymes. Synonyms: luxE (gene name); acyl-protein synthetase; long-chain-fatty-acid-luciferin-component ligase. Enzyme Commission Number: EC 6.2.1.19. CAS No. 82657-98-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5677; long-chain-fatty-acid-protein ligase; EC 6.2.1.19; 82657-98-5; luxE (gene name); acyl-protein synthetase; long-chain-fatty-acid-luciferin-component ligase. Cat No: EXWM-5677.
long-chain-fatty-acyl-glutamate deacylase
Does not act on acyl derivates of other amino acids. Optimum chain length of acyl residue is 12 to 16. Group: Enzymes. Synonyms: long-chain aminoacylase; long-chain-fatty-acyl-glutamate deacylase; long-chain acylglutamate amidase; N-acyl-D-glutamate deacylase. Enzyme Commission Number: EC 3.5.1.55. CAS No. 82249-69-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4444; long-chain-fatty-acyl-glutamate deacylase; EC 3.5.1.55; 82249-69-2; long-chain aminoacylase; long-chain-fatty-acyl-glutamate deacylase; long-chain acylglutamate amidase; N-acyl-D-glutamate deacylase. Cat No: EXWM-4444.
Longchain Nylon 3D Printing Filament
Longchain Nylon 3D Printing Filament. Group: 3d printing materials.
Longdaysin
Longdaysin is an inhibitor of protein kinases including CKIδ, CKIα, ERK2 and CDK7 with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM, respectively. Longdaysin inhibits Wnt/β-catenin signaling pathway and exhibits antitumor activity. Synonyms: 9-Isopropyl-N-(3-(trifluoromethyl)benzyl)-9H-purin-6-amine. CAS No. 1353867-91-0. Molecular formula: C16H16F3N5. Mole weight: 335.33.
A cell-permeable purine compound that acts as a reversible and ATP-competitive dual inhibitor of CKIa and CKId activities (IC50 = 5.6 and 8.8uM) with moderate selectivity over Cdk7 and Erk2 (IC50 = 29 and 52uM). Shown to block CKIa/d-mediated phosphorylation of PER1, a clock protein, (IC50 ~9uM) and repress PER1 proteasomal degradation, and lengthen the circadian period in U2OS cells (by ~13hrs at 10uM) much more effectively than Casein Kinase I Inhibitor, D4476 and IC261 and in larval zebra fish. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Longestin
It is produced by the strain of Streptomyces argenteolus A-2. Longestin inhibited Ca2+ and CAM-PDE in bovine brain with an IC50 of 0.065 μmol/L. Synonyms: KS-505a; 2-((6-carboxy-4, 5-dihydroxy-3-methoxytetrahydro-2H-pyran-2-yl)oxy)-14-hydroxy-8a, 10a-bis(hydroxymethyl)-14-(3-methoxy-3-oxopropyl)-1, 4, 4a, 6, 6a, 17b, 19b, 21b-octamethyl-16-oxo-2, 3, 4, 4a, 4b, 5, 6, 6a, 6b, 7, 8, 8a, 8b, 9, 10, 10a, 14, 16, 17, 17a, 17b, 18, 19, 19a, 19b, 20, 21, 21a, 21b, 22, 23, 23a-dotriacontahydro-1H-benzo[9, 10]piceno[3, 4-a]furo[3, 4-j]xanthene-1-carboxylic acid. CAS No. 131774-53-3. Molecular formula: C61H88O17. Mole weight: 1093.34.
Longicin
Longicin is an antibacterial peptide isolated from Haemaphysalis longicornis. It has activity against bacteria and parasitic. Synonyms: Gly-Phe-Gly-Cys-Pro-Leu-Asn-Gln-Gly-Ala-Cys-His-Asn-His-Cys-Arg-Ser-Ile-Gly-Arg-Arg-Gly-Gly-Tyr-Cys-Ala-Gly-Ile-Ile-Lys-Gln-Thr-Cys-Thr-Cys-Tyr-Arg-Lys. Molecular formula: C35H64O7. Mole weight: 596.9.
Longicornsin
Longicornsin is an antibacterial peptide isolated from Haemaphysalis longicornis. It has activity against gram-positive bacteria and gram-negative bacteria and fungi. Synonyms: Asp-Phe-Gly-Cys-Gly-Gln-Gly-Met-Ile-Phe-Met-Cys-Gln-Arg-Arg-Cys-Met-Arg-Leu-Tyr-Pro-Gly-Ser-Thr-Gly-Phe-Cys-Arg-Gly-Phe-Arg-Cys-Met-Cys-Asp-Thr-His-Ile-Pro-Leu-Arg-Pro-Pro-Phe-Met-Val-Gly.