A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Lofexidine hydrochloride. Group: Biochemicals. Alternative Names: 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole Hydrochloride. Grades: Highly Purified. CAS No. 21498-08-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H13Cl3N2O. US Biological Life Sciences.
Worldwide
Lofexidine hydrochloride
Lofexidine (hydrochloride) is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Baq-168; MDL-14042. CAS No. 21498-08-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1052.
Lofexidine hydrochloride
Lofexidine hydrochloride is the hydrochloride salt form of Lofexidine. Lofexidine, an analogue of clonidine, is an α2A-adrenergic receptor agonist for the treatment of opioid withdrawal symptoms as well as an anihypertensive. Uses: α2-adrenoceptor agonist related structurally to clonidine. used in treatment of opioid withdrawal symptoms; antihypertensive. Synonyms: 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole;hydrochloride 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline BritLofex lofexidine lofexidine hydrochloride Lofexidine mono-hydrochloride lofexidine monohydrochloride lofexidine, (+-)-isom. Grades: ≥98%. CAS No. 21498-08-8. Molecular formula: C11H13Cl3N2O. Mole weight: 295.59.
A vasoactive agent related structurally to Clonidine. Group: Biochemicals. Alternative Names: MDL-14042A, Ba-168, Britlofex, Lofetensin,Loxacor. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Loflucarban
Loflucarban is an antifungal agent. Synonyms: Loflucarban; NSC 76851; NSC-76851; NSC76851; Fluonilid; Fluonilide; 3,5-Dichloro-4'-fluorothiocarbanilide; 1-(3,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea. CAS No. 790-69-2. Molecular formula: C13H9Cl2FN2S. Mole weight: 315.187.
loganate O-methyltransferase
Also acts on secologanate. Methylates the 11-carboxy group of the monoterpenoid loganate. Group: Enzymes. Synonyms: loganate methyltransferase; S-adenosyl-L-methionine:loganic acid methyltransferase. Enzyme Commission Number: EC 2.1.1.50. CAS No. 39391-10-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1954; loganate O-methyltransferase; EC 2.1.1.50; 39391-10-1; loganate methyltransferase; S-adenosyl-L-methionine:loganic acid methyltransferase. Cat No: EXWM-1954.
Loganic acid
Loganic acid. Group: Biochemicals. Alternative Names: Norloganin. Grades: Plant Grade. CAS No. 22255-40-9. Pack Sizes: 20mg. Molecular Formula: C16H24O10, Molecular Weight: 376.355999999999. US Biological Life Sciences.
Worldwide
Loganin
Loganin. Group: Biochemicals. Alternative Names: Meliatin; Loganoside. Grades: Plant Grade. CAS No. 18524-94-2. Pack Sizes: 20mg. Molecular Formula: C17H26O10, Molecular Weight: 390.382. US Biological Life Sciences.
Worldwide
Loganin
Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Loganoside. CAS No. 18524-94-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0512.
Logwood Extract
Logwood Extract. Applications: Used as coloring in the production of beverage, food, supplement and cosmetic industry. Group: Others. Synonyms: Logwood Extract; Haematoxylum campechianum L. Purity: 5-10:1 By TLC. Appearance: Black fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Wood. Species: Haematoxylum campechianum L. Logwood Extract; Haematoxylum campechianum L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-119.
Lokivetmab
Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody that can be used for the research of atopic dermatitis (AD) in dogs [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Canine IL31 Recombinant Antibody. CAS No. 1533403-95-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99301.
Lolamicin
Lolamicin is a Gram-negative specific antibiotic. Lolamicin is active against more than 130 multidrug-resistant clinical isolates, has shown efficacy in multiple mouse models of acute pneumonia and sepsis infection, and protects the gut microbiome of mice against secondary infection with Clostridium difficile. The selective killing of pathogenic gram-negative bacteria by Lolamicin is a result of the low sequence homology of pathogenic bacteria and symbiotic bacteria. Lolamicin can be used in the study of infection caused by Gram-negative pathogens [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2930690-12-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164036.
L-olivosyl-oleandolide 3-O-methyltransferase
The enzyme is involved in the biosynthesis of the macrolide antibiotic oleandomycin in Streptomyces antibioticus. It can also act on other monoglycosylated macrolactones, including L-rhamnosyl-erythronolide B and L-mycarosyl-erythronolide B. Group: Enzymes. Synonyms: OleY. Enzyme Commission Number: EC 2.1.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1842; L-olivosyl-oleandolide 3-O-methyltransferase; EC 2.1.1.239; OleY. Cat No: EXWM-1842.
Lomatium Dissectum Root (Whole) & (Cut & Sifted)
Lomatium Dissectum Root (Whole) & (Cut & Sifted).
CA, FL & NJ
Lombartinib impurity
Lombartinib impurity. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H24ClN5O5. Mole Weight: 509.95. Catalog: APB10689.
Lombartinib impurity2
Lombartinib impurity2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1069122-99-1. Molecular Formula: C7H7ClN2O2. Mole Weight: 186.6. Catalog: APB1069122991.
Lombartinib impurity 3
Lombartinib impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H10ClNO3. Mole Weight: 251.67. Catalog: APB10690.
Lombartinib impurity 4
Lombartinib impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H10ClNO3. Mole Weight: 251.67. Catalog: APB10692.
Lombartinib impurity 5
Lombartinib impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H15ClN2O4. Mole Weight: 358.78. Catalog: APB10691.
Lombartinib impurity 6
Lombartinib impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H15ClN2O4. Mole Weight: 358.78. Catalog: APB10693.
Lombazole
Lombazole is used as an antimicrobial agent of the imidazole class. Uses: Lombazole is used as an antimicrobial agent of the imidazole class. Synonyms: Bay h 6020; Lombazolum; Lombazol; 1-([1,1'-biphenyl]-4-yl(2-chlorophenyl)methyl)-1H-imidazole; (2-Chlorophenyl)-imidazol-1-yl-(biphenyl-4-yl)methane. Grades: 98%. CAS No. 60628-98-0. Molecular formula: C22H17ClN2. Mole weight: 344.84.
lombricine kinase
Also acts on methylated lombricines such as thalassemine; the specificity varies with the source species. Group: Enzymes. Enzyme Commission Number: EC 2.7.3.5. CAS No. 9026-53-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3185; lombricine kinase; EC 2.7.3.5; 9026-53-3. Cat No: EXWM-3185.
Lomefloxacin
Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms, which is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used as a pre-operative prophylactic to prevent urinary tract infection caused by S. pneumoniae, H. influenzae, S. aureus, P. aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E. coli, and K. pneumoniae. It is used to induce genomic instability in mice1 and modification of the kinetics of growth of Gram-negative bacteria. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. Uses: Anti-bacterial agents. Synonyms: Maxaquin; SC47111A. Grades: >98%. CAS No. 98079-51-7. Molecular formula: C17H19F2N3O3. Mole weight: 351.35.
Lomefloxacin·HCl 99+% (HPLC)
Lomefloxacin·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Lomefloxacin hydrochloride
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C17H19F2N3O3 · HCl. CAS No. 98079-51-7. Prepack ID 39370200-1g. Molecular Weight 387.81. See USA prepack pricing.
Lomefloxacin hydrochloride
Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic , with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC47111A hydrochloride. CAS No. 98079-52-8. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0455.
Lomefloxacin, Hydrochloride
Fluorinated quinolone antibacterial. DNA gyrase antagonist. Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic. Lomefloxacin is an orally bioavailable, broad-spectrum fluoroquinolone antibiotic.1 In vitro, it inhibits growth of N. gonorrhoeae, E. coli, K. pneumoniae, P. vulgaris, S. epidermidis, and M. morganii (MIC90s = 0.1, 0.39, 0.39, 0.39, 0.39, and 0.78ug/ml, respectively). It also inhibits growth of S. aureus and methicillin-resistant S. aureus (MRSA; MIC90 = 3.13ug/ml for both) and of H. influenzae and ampicillin-resistant H. influenzae (MIC90 = 0.1ug/ml for both). In vivo, lomefloxacin inhibits the growth of P. mirabilis, E. coli, K. pneumoniae, and S. aureus (ED50s = 1.39, 1.45, 1.78, and 6.66mg/kg, respectively) in mouse models of systemic infection. It inhibits bacterial DNA gyrase, thereby inhibiting DNA synthesis and bacterial growth.2 Formulations containing lomefloxacin have been used in the treatment of bronchitis and urinary tr Group: Biochemicals. Alternative Names: 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Alkaflox; Bareon; Chimono; Lomebact; Lomef 400; Lomflox; Lomitas; Lomoxin; Maxaquin; Mazaquin; NY 198; Orchacin; SC 47111; Uniquin. Grades: Highly Purified. CAS No. 98079-52-8. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C17H20ClF2N3O3, Molecular Weight: 387.81. US Biological Life Sciences.
Worldwide
Lomeguaritrib
Lomeguaritrib. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-(4-Bromothenyloxy)-7H-purin-2-amine. Product Category: Thiophenes. Appearance: Off-White Solid. CAS No. 192441-08-0. Molecular formula: C10H8BrN5OS. Mole weight: 326.17. Purity: 95%+. Product ID: ACM192441080. Alfa Chemistry ISO 9001:2015 Certified.
Lomeguatrib
Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment. Synonyms: PaTrin 2; PaTrin2; PaTrin-2; Lomeguatrib; Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine. CAS No. 192441-08-0. Molecular formula: C10H8BrN5OS. Mole weight: 326.172.
Lomeguatrib
Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts. Group: Biochemicals. Alternative Names: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy]-1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2. Grades: Highly Purified. CAS No. 192441-08-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Lomerizine dihydrochloride
Lomerizine dihydrochloride is an antagonist of L- and T-type voltagegated calcium channels. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB-2796. CAS No. 101477-54-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-B0768A.
Lomerizine dihydrochloride
This product is a diphenylpiperazine calcium channel blocker with selective cerebral vasodilation. Synonyms: 1- (4, 4'-Difluorobenzhydryl) -4- (2, 3, 4-trimethoxybenzyl) piperazine·dihydrochloride; Flometizinehydrochloride; Lomerizinedihydrochloride, 99%, anewL-andT-typecalciumchannelblocker; Lomerizine2HCl; KB-2796dihydrochlorideChemicalbook; Piperazine, 1-[bis (4-fluorophenyl) methyl]-4-[ (2, 3, 4-trimethoxyphenyl) methyl]-, hydrochloride (1: 2) ; Lomerizinedihydrochloride, >=99%; 1- (Bis (4-fluorophenyl) methyl) -4- (2, 3, 4-trimethoxybenzyl) piperazinedihydrochloride. CAS No. 101477-54-7. Product ID: PAP-0072. Molecular formula: C27H32Cl2F2N2O3. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Lomerizine dihydrochloride; PAP-0072; Cardiovascular; C27H32Cl2F2N2O3; 101477-54-7. Appearance: white to tan. Standard: CP. Chemical Name: 1- (4, 4'-Difluorobenzhydryl) -4- (2, 3, 4-trimethoxybenzyl) piperazine·dihydrochloride. Grade: Pharmaceutical Grade. Solubility: DMSO: ≥30mg/mL. Storage: Inert atmosphere,2-8°C. Product Description: This product is a diphenylpiperazine calcium channel blocker with selective cerebral vasodilation.
Lomerizine Dihydrochloride
Lomerizine dihydrochloride, an L- and T-type voltagegated calcium channel blocker, is a selective cerebral vasodilator and antimigraine. Uses: Calcium channel blockers. Synonyms: KB-2796; 1-(2,3,4-Trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine dihydrochloride; Terranas; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2); KB 2796; KB2796. Grades: >98%. CAS No. 101477-54-7. Molecular formula: C27H30F2N2O3.2HCl. Mole weight: 541.46.
Lometraline, an aminotetralin derivative, is a potential antidepressant and/or anxiolytic agent. Uses: A potential antidepressant and/or anxiolytic agent. Synonyms: 8-chloro-5-methoxy-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride. Grades: ≥98%. CAS No. 34552-78-8. Molecular formula: C13H19Cl2NO. Mole weight: 276.20.
Lometrexol
Lometrexol is a folate analog antimetabolite with antineoplastic activity. As the 6R diastereomer of 5,10-dideazatetrahydrofolate, lometrexol inhibits glycinamide ribonucleotide formyltransferase (GARFT), the enzyme that catalyzes the first step in the de novo purine biosynthetic pathway, thereby inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation. The agent has been shown to be active against tumors that are resistant to the folate antagonist methotrexate. Uses: Antimetabolites, antineoplastic. Synonyms: Lometrexol; LMTX; LY 264618; LY-264618; LY264618. CAS No. 106400-81-1. Molecular formula: C21H25N5O6. Mole weight: 443.46.
Lometrexol disodium
Lometrexol is a folate analog antimetabolite with antineoplastic activity. Synonyms: LY 264618 disodium; LY264618 disodium; NSC-722969; NSC 722969; L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-, disodium salt. Grades: 98%. CAS No. 120408-07-3. Molecular formula: C21H23N5Na2O6. Mole weight: 487.42.
Lomevactone
Lomevactone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Lomevactone, Lomevactone [INN], UNII-TP71SPS85C, CID100079, LS-127471, (3-alpha,4-beta,6-alpha)-Tetrahydro-4-(4-chlorophenyl)-6-methyl-3-phenyl-2H-pyran-2-one, Chloro-4 phenyl-4 methyl-6 phenyl-3 tetrahydro-3,4,5,6 pyrone-6 (3R*,4S*,6R*) [French], 2H-Pyran-2-one, tetrahydro-4-(4-chlorophenyl)-6-methyl-3-phenyl-, (3-alpha,4-beta,6-alpha)-, Chloro-4 phenyl-4 methyl-6 phenyl-3 tetrahydro-3,4,5,6 pyrone-6 (3R*,4S*,6R*), 75115-73-0, 81478-25-3. Product Category: Heterocyclic Organic Compound. CAS No. 81478-25-3. Molecular formula: C18H17ClO2. Mole weight: 300.783. Purity: 0.96. IUPACName: 4-(4-chlorophenyl)-6-methyl-3-phenyloxan-2-one. Canonical SMILES: CC1CC(C(C(=O)O1)C2=CC=CC=C2)C3=CC=C(C=C3)Cl. Density: 1.182g/cm³. Product ID: ACM81478253. Alfa Chemistry ISO 9001:2015 Certified.
Lomibuvir
Lomibuvir is an nonnucleoside NS5B polymerase inhibitor. It inhibits the 1b/Con1 HCV subgenomic replicon. It binds to the HCV polymerase with dissociation constants of 17 nM. It demonstrated effective antiviral efficacy and may be used for the treatment of HCV. It was developed by ViroChem Pharma, which was acquired by Vertex Pharmaceuticals in 2009. It is in clinical phase 2 with no progress. Uses: Lomibuvir demonstrated effective antiviral efficacy and may be used for the treatment of hcv. Synonyms: 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-; 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid; 5- (3, 3-Dimethyl-1-butynyl) -3-[ (trans-4-hydroxycyclohexyl) [ (trans-4-methylcyclohexyl) carbonyl]amino]thiophene-2-carboxylic acid; VCH 222; VX 222. Grades: >98 %. CAS No. 1026785-55-6. Molecular formula: C25H35NO4S. Mole weight: 445.62.
Lomifylline
Lomifylline is a derivative of Xanthine (HY-W017389). Lomifylline can be used in research of sepsis and septic or endotoxic shock, when combined with an antibody to TNF or a TNF binding fragment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10226-54-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114531.
Lomitapide
Lomitapide (AEGR-733; BMS-201038) is a potent inhibitor of microsomal triglyceride-transfer protein ( MTP ) with an IC 50 of 8 nM in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEGR-733; BMS-201038. CAS No. 182431-12-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14667.
Lomitapide
Lomitapide. Group: Biochemicals. Alternative Names: N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide; AEGR 733; BMS 201038; BMS 201038-01; BMS 201238. Grades: Highly Purified. CAS No. 182431-12-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C39H37F6N3O2, Molecular Weight: 693.72. US Biological Life Sciences.
Worldwide
Lomitapide
Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Uses: The treatment of familial hypercholesterolemia. Synonyms: Juxtapid; Lojuxta; AEGR 733; AEGR-733; AEGR733; BMS-201038. Grades: > 98%. CAS No. 182431-12-5. Molecular formula: C39H37F6N3O2. Mole weight: 693.734.
Lomitapide Impurity 1
Lomitapide Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 182439-11-8. Molecular Formula: C20H18F3NO3. Mole Weight: 377.36. Catalog: APB182439118.
Lomitapide mesylate
Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEGR-733 mesylate; BMS-201038 mesylate. CAS No. 202914-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14668.
Lomitapide Mesylate
Lomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Synonyms: Lomitapide mesylate; 202914-84-9; BMS 201038-04; Juxtapid; Lomitapide (mesylate). Grades: >98%. CAS No. 202914-84-9. Molecular formula: C40H41F6N3O5S. Mole weight: 789.83.
L-Omithine HCL
L-ornithine hydrochloride is an important basic raw material in pharmaceutical industry, an important metabolite in cells, and plays an important regulatory role in the elimination of liquid ammonia in living organisms. Synonyms: L-ORNITHINE HYDROCHLORIDE SALT;L-(+)-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE-OH HCL;L-ORNITHINE-OH HYDROCHLORIDE;L-ORN HCL;L-ORNITHINE HCL;L(+)-ORNITHINE HYDROCHLORIDE. CAS No. 3184-13-2. Product ID: PAP-0030. Molecular formula: C5H13ClN2O2. Category: Amino acid. Product Keywords: Amino Acid Series; L-Omithine HCL; PAP-0030; Amino acid; C5H13ClN2O2; 3184-13-2. Appearance: at 100.00 %. mild green bark. Chemical Name: L(+)-Ornithine hydrochloride. Grade: Pharmaceutical Grade. Solubility: H2O: 100 mg/mL. Storage: Keep in dark place,Inert atmosphere,Room temperature. Applications: L-ornithine hydrochloride has the effect of treating liver cirrhosis, enhancing human immunity and resisting fatigue. Melting Point: 245 °C (dec.)(lit.). Density: 1.57. Product Description: L-ornithine hydrochloride is an important basic raw material in pharmaceutical industry, an important metabolite in cells, and plays an important regulatory role in the elimination of liquid ammonia in living organisms.
Lomofungin
It is produced by the strain of Str. lomondensis var. lomondensis NRRL 3252. It is an antibiotic of the phenazine derivatives. It has anti-bacterial and fungal effects, but the anti-bacterial effects are weak. Synonyms: Lomondomycin; NSC 106995; NSC 156939; U-24792; 1-carbomethoxy-5-formyl-4,6,8-trihydroxyphenazine; 6-Formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid methyl ester. Grades: >95%. CAS No. 26786-84-5. Molecular formula: C15H10N2O6. Mole weight: 314.25.
Lomustine
Lomustine (420 μM) triggers apoptosis through the mitochondrial pathway via decrease in the level of the anti-apoptosis proteins Bcl-2 and Bcl-xl, respectively. Uses: Antineoplastic agents, alkylating. Synonyms: nsc79037; nsc 79037; nsc-79037. Grades: >98%. CAS No. 13010-47-4. Molecular formula: C9H16ClN3O2. Mole weight: 233.7.
Lomustine
Chloroethylnitrosourea derivative with antitumor activity. Similar to carmustine, chlorozotocin, nimustine, ranimustine. Antineoplastic. Group: Biochemicals. Alternative Names: N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea. Grades: Highly Purified. CAS No. 13010-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Lomustine
Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCNU; NSC 79037. CAS No. 13010-47-4. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-13669.
Lomustine
250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H16ClN3O2. CAS No. 13010-47-4. Prepack ID 89981121-250mg. Molecular Weight 233.7. See USA prepack pricing.
Lomustine EP impurity C
Lomustine EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2387-23-7. Molecular Formula: C13H24N2O. Mole Weight: 224.34. Catalog: APB2387237.
Lonafarnib
Lonafarnib. Group: Biochemicals. Alternative Names: 4-[2-[4-[(11R)-3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide; Sarasar; Sch 66336. Grades: Highly Purified. CAS No. 193275-84-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H31Br2ClN4O2. US Biological Life Sciences.
Worldwide
Lonafarnib
Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras , K-ras and N-ras with IC 50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch66336. CAS No. 193275-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15136.
Lonafarnib
Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. Uses: Enzyme inhibitors. Synonyms: SCH 66336; SCH-66336; SCH66336; Sarasar. Grades: > 95%. CAS No. 193275-84-2. Molecular formula: C27H31Br2ClN4O2. Mole weight: 638.829.
Lonaprisan
Cas No. 211254-73-8.
Lonazolac
Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53808-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-W173309.
Loncastuximab
Loncastuximab (RB4v1.2) is an anti- CD19 monoclonal antibody. Loncastuximab shows antitumor activity and has potential application in non-Hodgkin's lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RB4v1.2. CAS No. 1875032-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99711.
Loncastuximab tesirine
Loncastuximab tesirine is a human cluster of differentiation 19 ( CD19 )-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis , it can be used for the research of diffuse large B-cell lymphoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Loncastuximab tesirine-lpyl; ADCT-402. CAS No. 1879918-31-6. Pack Sizes: 100 μg; 200 μg; 500 μg; 1 mg. Product ID: HY-P99349.
long-chain-3-hydroxyacyl-CoA dehydrogenase
This enzyme was purified from the mitochondrial inner membrane. The enzyme has a preference for long-chain substrates, and activity with a C16 substrate was 6- to 15-fold higher than with a C4 substrate (cf. EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase). Group: Enzymes. Synonyms: β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD. Enzyme Commission Number: EC 1.1.1.211. CAS No. 84177-52-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0116; long-chain-3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.211; 84177-52-6; β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD. Cat No: EXWM-0116.
long-chain acyl-[acyl-carrier-protein] reductase
Catalyses the reaction in the opposite direction. This enzyme, purified from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the NAD(P)H-dependent reduction of an activated fatty acid (acyl-[acp]) to the corresponding aldehyde. Together with EC 4.1.99.5, octadecanal decarbonylase, it is involved in alkane biosynthesis. The natural substrates of the enzyme are C16 and C18 activated fatty acids. Requires Mg2+. Group: Enzymes. Synonyms: long-chain acyl-[acp] reductase; fatty acyl-[acyl-carrier-protein] reductase; acyl-[acp] reductase. Enzyme Commission Number: EC 1.2.1.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1183; long-chain acyl-[acyl-carrier-protein] reductase; EC 1.2.1.80; long-chain acyl-[acp] reductase; fatty acyl-[acyl-carrier-protein] reductase; acyl-[acp] reductase. Cat No: EXWM-1183.
long-chain acyl-CoA dehydrogenase
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids β-oxidation. The enzyme from pig liver can accept substrates with acyl chain lengths of 6 to at least 16 carbon atoms. The highest activity was found with C12, and the rates with C8 and C16 were 80 and 70%, respectively. The enzyme from rat can accept substrates with C8-C22. It is most active with C14 and C16, and has no activity with C4, C6 or C24. cf. EC 1.3.8.1, short-chain acyl-CoA dehydrogenase, EC 1.3.8.8, medium-chain acyl-CoA dehydrogenase, and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase. Group: Enzymes. Synonyms: palmitoyl-CoA dehydrogenase; palmitoyl-coenzyme A dehydrogenase; long-chain acyl-coenzyme A dehydrogenase; long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase; ACADL (gene name). Enzyme Commission Number: EC 1.3.8.8. CAS No. 59536-74-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1415; long-chain acyl-CoA dehydrogenase; EC 1.3.8.8; 59536-74-2; palmitoyl-CoA dehydrogenase; palmitoyl-coenzyme A dehydrogenase; long-chain acyl-coenzyme A dehydrogenase; long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase; ACADL (gene name). Cat No: EXWM-1415.
long-chain acyl-CoA ω-monooxygenase
The enzymes from solanaceous plants are involved in the biosynthesis of stigmatic estolide, a lipid-based polyester that forms a major component of the exudate. Group: Enzymes. Synonyms: long-chain acyl-CoA ω-hydroxylase; CYP86A22 (gene name); CYP52M1 (gene name). Enzyme Commission Number: EC 1.14.13.204. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0806; long-chain acyl-CoA ω-monooxygenase; EC 1.14.13.204; long-chain acyl-CoA ω-hydroxylase; CYP86A22 (gene name); CYP52M1 (gene name). Cat No: EXWM-0806.
long-chain acyl-protein thioester reductase
Together with a hydrolase component (EC 3.1.2.2 and EC 3.1.2.14) and a synthetase component (EC 6.2.1.19), this enzyme forms a multienzyme fatty acid reductase complex that produces the long-chain aldehyde substrate of the bacterial luciferase enzyme (EC 1.14.14.3). The enzyme is acylated by receiving an acyl group from EC 6.2.1.19, and catalyses the reduction of the acyl group, releasing the aldehyde product. The enzyme is also able to accept the acyl group from a long-chain acyl-CoA. Group: Enzymes. Synonyms: luxC (gene name); acyl-CoA reductase; acyl coenzyme A reductase; long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); long-chain-fatty-acyl-CoA reductase. Enzyme Commission Number: EC 1.2.1.50. CAS No. 50936-56-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1154; long-chain acyl-protein thioester reductase; EC 1.2.1.50; 50936-56-6; luxC (gene name); acyl-CoA reductase; acyl coenzyme A reductase; long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); long-chain-fatty-acyl-CoA reductase. Cat No: EXWM-1154.