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A metabolite of Mycophenolic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Mycophenolic acid Cyclization impurity
Mycophenolic acid Cyclization impurity. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H18O6. Mole Weight: 306.31. Catalog: APB08687.
Mycophenolic Acid Cyclopropane Analogue
An impurity of Mycophenolic Acid which is a selective inhibitor of inosine monphosphate dehydrogenase. Synonyms: 1-Cyclopropane Mycophenolic Acid; 3-(2-((4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)methyl)-1-methylcyclopropyl)propanoic Acid; 2-[(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)methyl]-1-methyl-cyclopropanepropanoic Acid. Grades: > 95%. CAS No. 125198-40-5. Molecular formula: C18H22O6. Mole weight: 334.37.
Mycophenolic acid-d3
A labeled immunosuppressant. Prevents rejection in organ transplantation. Inhibits the enzyme needed for T cell and B cell growth. A broad-spectrum acting drug. Possesses antiviral, antifungal, antibacterial, anticancer, and antipsoriasis properties. Group: 2h labeled compounds. Alternative Names: (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-d3-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid. CAS No. 1185242-90-3. Molecular formula: C17H17D3O6. Mole weight: 323.36. Appearance: White solid. Catalog: ACM1185242903.
Mycophenolic acid-d3
Mycophenolic acid-d 3 is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Mycophenolate-d3. CAS No. 1185242-90-3. Pack Sizes: 1 mg. Product ID: HY-B0421S.
Labelled Mycophenolic Acid. Group: Biochemicals. Alternative Names: (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-d3-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mycophenolic Acid-d3 Acyl- β-D-glucuronide
A labeled metabolite of Mycophenolic Acid. Group: Biochemicals. Alternative Names: 1-[(4E)-6-(1,3-Dihydro-4-hydroxy-6-(methoxy-d3)-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-1-oxo-4-hexenoate] β-D-Glucopyranuronic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mycophenolic Acid-d3 β-D-Glucuronide
A labeled metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides. Group: Biochemicals. Alternative Names: 5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-(methoxy-d3)-7-methyl-3-oxo-4-isobenzofuranyl β-D-Glucopyranosiduronic Acid; Mycophenolic Acid-d3 Glucosiduronate; Mycophenolic Acid-d3 Glucuronide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A labeled metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides. Group: Biochemicals. Alternative Names: Methyl Mycophenolic Acid-d3 Methyl Ester Glucosiduronate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Mycophenolic acid (MPA) is used in combination with calcineurin inhibitors as maintenance immunosuppression for kidney transplant recipients. Group: Biochemicals. Alternative Names: CellCept, Myfortic. Grades: Highly Purified. CAS No. 24280-93-1. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Mycophenolic acid glucuronide
Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic acid glucuronide shows anti-tumor activity and can be used in adenocarcinoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31528-44-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-137301.
Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation has shown mycophenolic acid to display a broad range of pharmacological activities including antitumor, antiviral, antifungal and antiprotozoan activities. However, it was the discovery that mycophenolic acid was a potent immunosuppressant, useful to prevent kidney transplant rejection, that led to its commercial development and that of related semi-synthetics as pharmaceuticals. Mycophenolic acid acts by inihibition of inosine monophosphate dehydrogenase, controlling the rate of de novo purine synthesis in the proliferation of B and T lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 24280-93-1. Pack Sizes: 25mg. US Biological Life Sciences.
Used in the preparation of a Mycophenolic acid metabolite. Group: Biochemicals. Alternative Names: (4E)-6-[1,3-Dihydro-6-methoxy-7-methyl-3-oxo-4-[(2,3,4,6-tetra-O-acetyl- β-D-glucopyranosyl)oxy]-5-isobenzofuranyl]-4-methyl-4-hexenoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1186295-42-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Mycophenolic acid o-methyl impurity
Mycophenolic acid o-methyl impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 38877-93-9. Molecular Formula: C18H22O6. Mole Weight: 334.36. Catalog: APB38877939.
Mycophenolic Acid Phenolic β-D-Glucoside
A metabolite of Mycophenolic acid (phase II metabolism). Group: Biochemicals. Alternative Names: (4E)-6-[4-( β-D-Glucopyranosyloxy)-1,3-dihydro-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-4-methyl-4-hexenoic Acid. Grades: Highly Purified. CAS No. 55533-52-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mycophenolic Acid Phenolic beta-D-Glucoside
An impurity of Mycophenolic which inhibits an enzyme needed for the growth of T cells and B cells. Synonyms: (4E)-6-[4-(b-D-Glucopyranosyloxy)-1,3-dihydro-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-4-methyl-4-hexenoic acid. Grades: > 95%. CAS No. 55533-52-3. Molecular formula: C23H30O11. Mole weight: 482.48.
Mycophenolic Acid Related Compound 1
An impurity of Mycophenolic which is a selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase. Synonyms: 5,7-Dihydroxy-4 methylphthhalide. Grades: > 95%. Molecular formula: C9H8O4. Mole weight: 180.16.
Mycophenolic acid ring opening impurity
Mycophenolic acid ring opening impurity. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H22O7. Mole Weight: 338.36. Catalog: APB08686.
Mycophenolic acid sodium
Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase ( IMPDH ) inhibitor with an EC 50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Mycophenolate sodium. CAS No. 37415-62-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0421A.
Mycophenolic acid (Standard)
Mycophenolic acid (Standard) is the analytical standard of Mycophenolic acid. This product is intended for research and analytical applications. Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 24280-93-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0421R.
Mycophenolic acid (Z)-isomer
Mycophenolic acid (Z)-isomer. Uses: For analytical and research use. Group: Impurity standards. CAS No. 483-60-3. Molecular Formula: C17H20O6. Mole Weight: 320.34. Catalog: APB483603.
Mycoplanecin A
Mycoplanecin A is a cyclic peptide antibiotic produced by Actinoplanes aivajinensis subsp. mycoplanecinus. It has strong anti-mycobacterial, luteus, and Hypococcus activity. It also has moderate anti-Xanthomonas oryzae activity. It also has antibacterial effect on some strains of Actinomycetes. CAS No. 72993-51-2. Molecular formula: C61H102N10O13. Mole weight: 1183.52.
Mycoplanecin B
Mycoplanecin B is a cyclic peptide antibiotic produced by Actinoplanes aivajinensis subsp. mycoplanecinus. Synonyms: 2-(4-Methylproline)mycoplanecin A. CAS No. 81018-84-0. Molecular formula: C60H100N10O13. Mole weight: 1169.49.
Mycoplanecin C
Mycoplanecin C is a cyclic peptide compound produced by Actinoplanes aivajinensis subsp. mycoplanecinus. Synonyms: 9-(N-Methyl-2-aminoheptanoic acid)mycoplanecin A. CAS No. 81018-83-9. Molecular formula: C62H104N10O13. Mole weight: 1197.54.
Mycoplanecin D
Mycoplanecin D is a cyclic peptide compound produced by Actinoplanes aivajinensis subsp. mycoplanecinus. Synonyms: 2-(4-Propylproline)mycoplanecin A. CAS No. 89355-38-4. Molecular formula: C62H104N10O13. Mole weight: 1197.54.
mycoredoxin
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC 2.8.4.2 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione. Group: Enzymes. Synonyms: Mrx1; MrxI. Enzyme Commission Number: EC 1.20.4.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1242; mycoredoxin; EC 1.20.4.3; Mrx1; MrxI. Cat No: EXWM-1242.
Mycosporine-2-glycine is a natural product found in Anthopleura elegantissima. Synonyms: M2G; {[(5S)-3-[(Carboxymethyl)amino]-5-hydroxy-5-(hydroxymethyl)-2-methoxy-2-cyclohexen-1-ylidene]amino}acetic acid. Molecular formula: C12H18N2O7. Mole weight: 302.28.
Mycosporine glycine
Mycosporine glycine is a natural product found in Chlorogloeopsis. Synonyms: Marinox; Mycosporin glycine; Glycine, N-((5S)-5-hydroxy-5-(hydroxymethyl)-2-methoxy-3-oxo-1-cyclohexen-1-yl)-; Mycosporine-gly; N-[(5S)-5-Hydroxy-5-(hydroxymethyl)-2-methoxy-3-oxo-1-cyclohexen-1-yl]glycine; ((S)-5-Hydroxy-5-hydroxymethyl-2-methoxy-3-oxo-cyclohex-1-enylamino)-acetic acid. CAS No. 65318-21-0. Molecular formula: C10H15NO6. Mole weight: 245.23.
Mycothiol disulfide - Stabilised with trifluoroacetic acid ammonium salt
Mycothiol Disulfide is an indispensable biomedical compound,diligently aiding in studying an extensive array of tenacious bacterial infections. Its unparalleled prowess lies in its capacity to effectively obstruct bacterial proliferation while effortlessly surmounting drug resistance mechanisms. Elevating its impact further is a fortified formulation merged with the trifluoroacetic acid ammonium salt embodies unfaltering stability and amplified effectiveness. Synonyms: 1-O-[2-[[(2R)-2-(Acetylamino)-3-mercapto-1-oxopropyl]amino]-2-deoxy-α-D-glucopyranosyl]-D-myo-inositol disulfide; AcCys-GlcN-Ins. CAS No. 192126-76-4. Molecular formula: C34H58N4O24S2. Mole weight: 970.97.
mycothiol S-conjugate amidase
The enzyme that is found in actinomycetes is involved in the detoxification of oxidizing agents and electrophilic antibiotics. The enzyme has low activity with 1-O-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol as substrate (cf. EC 3.5.1.103, N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase). Group: Enzymes. Synonyms: MCA. Enzyme Commission Number: EC 3.5.1.115. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4395; mycothiol S-conjugate amidase; EC 3.5.1.115; MCA. Cat No: EXWM-4395.
mycothiol synthase
This enzyme catalyses the last step in the biosynthesis of mycothiol, the major thiol in most actinomycetes, including Mycobacterium. The enzyme is a member of a large family of GCN5-related N-acetyltransferases (GNATs). The enzyme has been purified from Mycobacterium tuberculosis H37Rv. Acetyl-CoA is the preferred CoA thioester but propionyl-CoA is also a substrate. Group: Enzymes. Synonyms: MshD. Enzyme Commission Number: EC 2.3.1.189. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2131; mycothiol synthase; EC 2.3.1.189; MshD. Cat No: EXWM-2131.
Mycothione
Mycothione is an efficacious antioxidant and detoxifying compound aiding in the research of an extensive array of drug-resistant microbial afflictions, including the notorious tuberculosis. Synonyms: Mycothione; MSSM; (2R, 2'R) -3, 3'-disulfanediylbis{2- (acetylamino) -N- [ (2R, 3R, 4R, 5S, 6R) -4, 5-dihydroxy-6- (hydroxymethyl) -2-{ [ (1S, 2R, 3R, 4S, 5S, 6R) -2, 3, 4, 5, 6-pentahydroxycyclohexyl] oxy}tetrahydro-2H-pyran-3-yl] propanamide}; Mycothiol disulfide; CHEBI:16086; Q27098374; (2R)-2-acetamido-3-[[(2R)-2-acetamido-3-[[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[(2R,3R,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]amino]-3-oxopropyl]disulfanyl]-N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[(2R,3R,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]propanamide; 2-acetylamino-3-[2-acetylamino-2-[[4,5-dihydroxy-6-(hydroxymethyl)-2-(2,3,4,5,6-pentahydroxycyclohexoxy)-tetrahydropyran-3-yl]carbamoyl]ethyl]disulfanyl-N-[4,5-dihydroxy-6-(hydroxymethyl)-2-(2,3,4,5,6-pentahydroxycyclohexoxy)-tetrahydropyran-3-yl]-propanamide. Molecular formula: C34H58N4O24S2. Mole weight: 970.97.
mycothione reductase
Contains FAD. No activity with glutathione, trypanothione or coenzyme A as substrate. Group: Enzymes. Synonyms: mycothiol-disulfide reductase. Enzyme Commission Number: EC 1.8.1.15. CAS No. 252212-92-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1641; mycothione reductase; EC 1.8.1.15; 252212-92-3; mycothiol-disulfide reductase. Cat No: EXWM-1641.
Mycotrienol I
Mycotrienol I is a polyene macrolide compound produced by Str. rishiriensis T-23. It has anti-fungal and anti-leukemia activity. Synonyms: Ansatrienol A; (4E,6S,7S,8R,10E,12E,14E,16R)-6,8-dihydroxy-16-methoxy-5,7-dimethyl-19-azabicyclo[18.3.1]tetracosa-1(23),4,10,12,14,20-hexaene-18,22,24-trione. CAS No. 81904-15-6. Molecular formula: C26H33NO6. Mole weight: 455.54.
Mycotrienol II
Mycotrienol II is a polyene macrolide compound produced by Str. rishiriensis T-23. It has anti-fungal and anti-leukemia activity. Synonyms: 20,23-Didehydro-20,23-dideoxo-20,23-dihydroxyansatrienol A; Ansatrienol A, 20,23-didehydro-20,23-dideoxo-20,23-dihydroxy-. CAS No. 84906-73-0. Molecular formula: C26H35NO6. Mole weight: 457.56.
Mycoversilin
Mycoversilin is an antibiotic produced by Aspergillus versicolor (N5)17. It has the activity of inhibiting skin fungi and phytopathogenic fungi, but has no anti-yeast and bacterial activity. It has a strong inhibitory effect on protein synthesis. Synonyms: 8,11-Dimethylpyrano(3,2-a)xanthene-1,5,6,9,10,12-hexol; Pyrano(3,2-a)xanthene-1,5,6,9,10,12-hexol, 8,11-dimethyl-. CAS No. 88527-18-8. Molecular formula: C18H16O8. Mole weight: 360.31.
Mycro 3
Mycro 3 is potent and selective inhibitor of Myc-Max dimerization. Synonyms: Mycro 3; Mycro3; Mycro-3; ethyl 5-[[7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-1-phenylpyrazole-4-carboxylate. CAS No. 944547-46-0. Molecular formula: C24H17ClF2N6O4. Mole weight: 526.88.
Myelin Basic Protein (87-99) is a encephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Myelin basic protein (MBP) is a potential target antigen because it induces experimental allergic encephalomyelitis (EAE) in susceptible animals. Synonyms: Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro; VHFFKNIVTPRTP. CAS No. 118506-26-6. Molecular formula: C74H114N20O17. Mole weight: 1555.8.
Myelin Basic Protein (87-99) acetate
Myelin Basic Protein (87-99) acetate is an encephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Myelin basic protein (MBP) is a potential target antigen because it induces experimental allergic encephalomyelitis (EAE) in susceptible animals. Synonyms: H-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH.CH3CO2H; L-valyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-asparagyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-L-proline acetic acid. Grades: ≥95%. Molecular formula: C76H118N20O19. Mole weight: 1615.87.
Myelin basic protein MBP is the second most abundant protein in the central nervous system myelin and is responsible for the adhesion of the cytosolic surfaces of multilayered compact myelin. Synonyms: Myelin Basic Protein (4-14); MBP(4-14) bovine; Myelin Basic Protein Fragment 4-14; L-Leucine, L-glutaminyl-L-Lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-; H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH; Myelin basic protein (4-14), N-acetylated. Grades: ≥95%. CAS No. 126768-94-3. Molecular formula: C60H103N21O17. Mole weight: 1390.59.
Myelin Basic Protein (MBP) (68-82), guinea pig
It is a fragment of myelin basic protein (MBP). Synonyms: (Des-Gly77,Des-His78)-Myelin Basic Protein (68-84) (guinea pig); Myelin Basic Protein Guinea Pig Fragment 68-82; H-Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-OH; L-tyrosyl-glycyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-lysyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-glutaminyl-L-alpha-aspartyl-L-alpha-glutamyl-L-asparagine. Grades: ≥95%. CAS No. 98474-59-0. Molecular formula: C71H113N23O28. Mole weight: 1736.79.
Myelin Basic Protein (MBP) (68-82), guinea pig
Myelin Basic Protein (MBP) (68-82), guinea pig is a fragment of myelin basic protein (MBP). Uses: Scientific research. Group: Peptides. CAS No. 98474-59-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1048.
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: MOG (35-55). CAS No. 149635-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1240.
myeloblastin
From polymorphonuclear leukocyte granules. In peptidase family S1 (trypsin family). Not inhibited by secretory leukocyte proteinase inhibitor. Group: Enzymes. Synonyms: leukocyte proteinase 3; leukocyte proteinase 4; Wegener's granulomatosis autoantigen; proteinase PR-3; proteinase-3; PMNL proteinase. Enzyme Commission Number: EC 3.4.21.76. CAS No. 128028-50-2. PRTN3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4168; myeloblastin; EC 3.4.21.76; 128028-50-2; leukocyte proteinase 3; leukocyte proteinase 4; Wegener's granulomatosis autoantigen; proteinase PR-3; proteinase-3; PMNL proteinase. Cat No: EXWM-4168.
Myeloid antimicrobial peptide
BMAPs (bovine myeloid antimicrobial peptides) are bovine cathelicidins that share many structural and functional features with human cathelicidin.
Myeloid antimicrobial peptide BMAP-27
BMAP-27 is a 26 amino-acid peptide with amidated C-terminus. It has shown potent antimicrobial effects against various species of bacteria and parasites. BMAP-27 was the most effective at killing Staphylococcus aureus, Streptococcus uberis, and Escherichia coli, and this was dependent on its amphipathic structure and cationic charge. However, it seems to have hemolytic effects on cultured blood cells, as well as cytotoxic effects to hematopoietic cells and activated human lymphocytes.
Myeloid antimicrobial peptide BMAP-28
A bovine myeloid antimicrobial peptide (BMAP-28) belongs to the cathelicidin family and exerts potent antimicrobial activity in order to protect animals from bacterial and fungal infections. Moreover, it has been indicated that the antimicrobial effect of BMAP-28 can be enhanced by altering its cationic and hydrophobic amino acid residues.
Myeloid cathelicidin 1
Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Synonyms: CATH-1 protein; CAP18; eCATH-1.
Myeloid cathelicidin 2
Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Synonyms: eCATH-2.
Myeloid cathelicidin 3
Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Furthermore, eCATH-3 showed potent activity against some fungi like C. neoformans and Rhodotorula rubra, but its activity depends on the salt concentration being strongly inhibited at the physiological salt concentration. Synonyms: eCATH-3.
myeloperoxidase
Contains calcium and covalently bound heme (proximal ligand histidine). It is present in phagosomes of neutrophils and monocytes, where the hypochlorite produced is strongly bactericidal. It differs from EC 1.11.1.10 chloride peroxidase in its preference for formation of hypochlorite over the chlorination of organic substrates under physiological conditions (pH 5-8). Hypochlorite in turn forms a number of antimicrobial products (Cl2, chloramines, hydroxyl radical, singlet oxygen). MPO also oxidizes bromide, iodide and thiocyanate. In the absence of halides, it oxidizes phenols and has a moderate peroxygenase activity toward styrene. Group: Enzymes. Synonyms: MPO; verdoperoxidase. Enzyme Commission Number: EC 1.11.2.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0513; myeloperoxidase; EC 1.11.2.2; MPO; verdoperoxidase. Cat No: EXWM-0513.
Myeloperoxidase, human white blood cells
Myeloperoxidase, human white blood cells (MPO) is a peroxidase. In Myeloperoxidase, human white blood cells mediate oxidative stress by promoting the production of reactive oxygen species (ROS) and active nitrogen (RNS), regulating the polarization and inflammation-related signaling pathways of microglia and neutrophils. Myeloperoxidase, human white blood cells has antibacterial activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MPO. CAS No. 9003-99-0. Pack Sizes: 5 U. Product ID: HY-125859A.
A 5-fluorotryptamine derivative that inhibits myeloperoxidase/MPO activity (IC50 = 18nM) via direct affinity interaction with enzyme active site heme pyrrole ring D, while exhibiting much reduced affinity toward serotonin reuptake transporter/SERT (Ki = 631nM). Kinetic studies reveal that the inhibitor acts as a good one-electron donor for the intermediate Compound I "Fe(IV)=O.Por +", facilitating the formation of Compound II (Fe(IV)-OH.Por) and thereby preventing the reduction of Compound I directly to the resting state "Fe(IV).Por" via the "halogenation cycle", while, on the other hand, behaves as a poor electron donor for Compound II, thereby preventing the completion of the "peroxidase cycle" by stalling the further reduction of Compound II to the resting state. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O, Primary Target: Myeloperoxidase. US Biological Life Sciences.
Worldwide
MYF-01-37
MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with the TEAD2 protein. Group: Inhibitors. Alternative Names: MYF-01-37; MYF 01-37; MYF01-37; MYF-0137; MYF 0137; MYF0137. CAS No. 2416417-65-5. Molecular formula: C15H17F3N2O. Mole weight: 298.31. Appearance: Solid powder. Purity: >98%. IUPACName: 1- (3-methyl-3- ( (3- (trifluoromethyl) phenyl) amino) pyrrolidin-1-yl) prop-2-en-1-one. Canonical SMILES: C=CC (N1CC (NC2=CC=CC (C (F) (F)F)=C2) (C)CC1)=O. Catalog: ACM2416417655.
MYK-461
MYK-461 is a myosin inhibitor that selectively decreases the ATPase activity of cardiac myosin heavy chain, thus it is potentially for the treatment of hypertrophic cardiomyopathy (HCM). Uses: Potential treatment of hypertrophic cardiomyopathy (hcm). Synonyms: SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; Mavacamten; 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione. Grades: 99%. CAS No. 1642288-47-8. Molecular formula: C15H19N3O2. Mole weight: 273.33.
Myoglobin
Myoglobin is a small molecular pigment protein formed by binding globin to Heme, which can be reversibly bound to oxygen to form MbO 2 , MbO 2 is called oxymyoglobin, and Mb is called deoxymyoglobin. Myoglobin has the role of transporting and storing oxygen in muscle cells [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 100684-32-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-NP007.
MYOGLOBIN
Heterocyclic Organic Compound. CAS No. 11080-17-4. Purity: 0.96. Catalog: ACM11080174.
myo-Inositol 1,2,3,4,6-pentakisphosphate, a bioactive molecule, has proved its worth in the biomedical industry as an effective cancer cell growth inhibitor with potential for treating hepatocellular and colorectal cancers. This powerful compound inhibits ROCK signaling pathways, which are implicated in cancer cell migration and invasion, making it an important target for new drug development. Researchers also believe that myo-Inositol 1,2,3,4,6-pentakisphosphate could help to regulate glucose metabolism, opening up possibilities for novel diabetes treatments. Synonyms: InsP5. CAS No. 861922-14-7. Molecular formula: C6H17O21P5. Mole weight: 580.06.
myo-Inositol 1,2,3,5,6-pentakisphosphate
myo-Inositol 1,2,3,5,6-pentakisphosphate is a prominent inositol polyphosphate widely employed in the biomedical sector, exhibiting significant intricacy in signal transduction pathways and cellular mechanisms. Its pivotal function as a modulator of intracellular calcium levels aids in scientific research, particularly in relation to cancer, diabetes and neurodegenerative ailments. Synonyms: InsP5. CAS No. 26326-85-2. Molecular formula: C6H17O21P5. Mole weight: 580.06.
myo-Inositol 1,2,4,5,6-pentakisphosphate
myo-Inositol 1,2,4,5,6-pentakisphosphate is a signaling molecule used for biomedical research of cardiovascular adversaries and the insidious threats of diabetes. Synonyms: InsP5. Molecular formula: C6H17O21P5. Mole weight: 580.06.