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| Product | Description | |
|---|---|---|
| McN-A 343 | McN-A 343 is a partial agonist with similar affinity at all five muscarinic acetylcholine receptor subtypes and its relative selectivity depends on a higher efficacy at the M1 (and M4) subtypes. Its selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1 receptors. Uses: Nicotinic agonists. Synonyms: [4-(m-Chlorophenylcarbamoyloxy)-2-butynyl]trimethylammonium Chloride; 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium Chloride; m-Chlorocarbanilate (4-Hydroxy-2-butynyl)trimethylammonium Chloride; A 343; McN 343; McN-A 343-11. Grades: ≥99% by HPLC. CAS No. 55-45-8. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.21. |  |
| McN-A-343 | McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis [1] [2]. McN-A-343 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 55-45-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107648. |  |
| MCOPPB | MCOPPB is a drug which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07 and much weaker activity at other opioid receptors. MCOPPB exhibited potent anxiolytic effects in mouse models, and inhibited signaling through nociceptin receptor in the mouse brain. Synonyms: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole. Grades: >98%. CAS No. 1028969-49-4. Molecular formula: C26H40N4. Mole weight: 408.634. | |
| MCOPPB triHydrochloride | The trihydrochloride salt form of MCOPPB, an effective full agonist of nociceptin receptor, could be a good antianxiety agent with few side-effects. pKi: 10.07. Uses: The trihydrochloride salt form of mcoppb could be a good antianxiety agent with few side-effects. Synonyms: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole; trihydrochloride; MCOPPBtrihydrochloride; 1028969-49-4; 1108147-88-1; 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-Benzimidazoletrihydrochloride. Grades: 95%. CAS No. 1108147-88-1. Molecular formula: C26H40N4.3HCL. Mole weight: 518.01. | |
| MCOPPB Trihydrochloride | A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. Group: Biochemicals. Alternative Names: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059. Grades: Highly Purified. CAS No. 1108147-88-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| m-Coumaric acid | m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. Uses: Scientific research. Group: Natural products. CAS No. 588-30-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-113357. | |
| MCP110 | MCP110 is a Ras/Raf-1 interaction inhibitor. The Ras signaling pathway is activated either by direct mutation of Ras or its effector B-Raf. MCP110 was shown to inhibit proliferation of tumor cells. Synonyms: MCP110; MCP-110; MCP 110; N-(4-(benzyloxy)-3-methoxybenzyl)-5-phenyl-N-(2-(pyridin-2-yl)ethyl)pentanamide. CAS No. 521310-51-0. Molecular formula: C33H36N2O3. Mole weight: 508.662. | |
| MCPA | MCPA is a phenoxy herbicide, and widely used to control annual and perennial broad leaved weeds, including poppy, thistles and docks, in crops such as cereals, rice, linseed, flax, grassland and turf [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 94-74-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0859. | |
| MCP(Modified Citrus Pectin) | MCP(Modified Citrus Pectin). Categories: ore. |  CA, FL & NJ |
| mCPPO1 | Organic Light Emitting Diode (OLED). Alternative Names: 9-(3-(9H -Carbazol-9-yl)phenyl)-3-(diphenylphosphoryl)-9H -carbazole. CAS No. 1296229-26-9. Molecular formula: C42H29N2OP. Mole weight: 608.67 g/mol. Catalog: ACM1296229269. |  |
| mCRAMP | Cas No. 376364-36-2. | |
| m-Cresol | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-100g. Molecular Weight 108.14. See USA prepack pricing. |  |
| m-Cresol | 500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-500g. Molecular Weight 108.14. See USA prepack pricing. | |
| M-Cresol | M-Cresol. Group: Biochemicals. Grades: Highly Purified. CAS No. 108-39-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H8O. US Biological Life Sciences. | Worldwide |
| MCT - Medium Chain Triglyceride | MCT - Medium Chain Triglyceride (Caprylic / Capric Triglyceride). CAS No. 73398-61-5. Kosher: Y. VIGON Item # 507177. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essetial Oils. |  America & Internationally |
| MCTR3 | MCTR3 is a potent cytokine of pro-resolving mediating maresin conjugates in tissue regeneration (MCTR), which reduces the inflammatory response and promotes the tissue regeneration. MCTR3 exhibits potency in ameliorating LPS-induced acute lung injury and arthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1784701-63-8. Pack Sizes: 10 μg (215.69 μM * 100 μL in Ethanol)); 25 μg (215.69 μM * 250 μL in Ethanol). Product ID: HY-125516. | |
| MCU-i4 | MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth. Group: Others. Alternative Names: MCU-i4; MCUi4; MCU i4. CAS No. 371924-24-2. Molecular formula: C23H27N3O2. Mole weight: 377.49. Appearance: Solid powder. Purity: >98%. IUPACName: Ethyl 4-((4-(diethylamino)phenyl)amino)-6-methylquinoline-3-carboxylate. Canonical SMILES: O=C (C1=C (NC2=CC=C (N (CC)CC)C=C2)C3=CC (C)=CC=C3N=C1)OCC. Catalog: ACM371924242. | |
| m-Cyanobenzyl chloride | m-Cyanobenzyl chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 64407-07-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| M-CYANOPHENYLGLYOXAL HYDRATE | Heterocyclic Organic Compound. Alternative Names: 3-CYANOPHENYLGLYOXAL HYDRATE;M-CYANOPHENYLGLYOXAL HYDRATE. CAS No. 1071555-51-5. Molecular formula: C9H7NO3. Mole weight: 177.15678. Catalog: ACM1071555515. | |
| m-Cymene | m-Cymene. Group: other glass and ceramic materials. Alternative Names: 1-Isopropyl-3-methylbenzene; meta-isopropyltoluene; 3-Isopropyltoluene; M-CYMENE; 1-Methyl-3-isopropylbenzene; 1-Isopropyl-3-methylbenzene,3-Isopropyltoluene; m-Isopropyltoluene; m-Cymol; 3-Methylisopropylbenzene; m-Methylisopropylbenzene. CAS No. 535-77-3. Product ID: 1-methyl-3-propan-2-ylbenzene. Molecular formula: 134.22. Mole weight: C10H14. CC1=CC(=CC=C1)C(C)C. XCYJPXQACVEIOS-UHFFFAOYSA-N. ?95%. |  |
| MD001 | MD001 is a dual peroxisome proliferator-activated receptor PPARα/PPARγ agonist. It increases the transcriptional activity of PPARα and PPARγ, improving the expression of genes associated with β-oxidation and fatty acid and glucose uptake. It significantly improved blood metabolic parameters in db/db mice. Synonyms: MD001; 2254605-76-8; 5,7-dihydroxy-8-methyl-4-phenyl-3-[(E)-3-phenylprop-2-enoyl]chromen-2-one; 5,7-dihydroxy-8-methyl-3-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-4-phenyl-2H-1-benzopyran-2-one; AKOS040754842. Grades: ≥90%. CAS No. 2254605-76-8. Molecular formula: C25H18O5. Mole weight: 398.41. | |
| MD2-IN-1 | MD2-IN-1 is an inhibitor of myeloid differentiation protein 2 (MD2) with a KD of 189 μM for recombinant human MD2 (rhMD2). Synonyms: (2E)-1-(3,4-Dimethoxyphenyl)-3-(3,4,5-Trimethoxyphenyl)Prop-2-En-1-One; MDK7229. Grades: 98%. CAS No. 111797-22-9. Molecular formula: C20H22O6. Mole weight: 358.4. | |
| MDA 19 | MDA 19 is a potent and selective agonist of human cannabinoid receptor 2 (CB2) , with a K i of 43.3 nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1048973-47-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15451. | |
| MDA-MB Transfection Reagent | Transfection Reagent for MDA-MB Breast Adenocarcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1794. |  Nevada, Texas, USA |
| MDBN, p97 Inhibitor (3,4-Methylenedioxy-b-nitrostyrene) | Cell-permeable. An irreversible inhibitor of p97 (IC50 <10uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1485-00-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| mDCBPy | mDCBPy. Group: Organic light-emitting diode (oled) materials. CAS No. 1867199-59-4. Product ID: [3,5-di(carbazol-9-yl)phenyl]-pyridin-4-ylmethanone. Molecular formula: 513.6g/mol. Mole weight: C36H23N3O. C1=CC=C2C (=C1) C3=CC=CC=C3N2C4=CC (=CC (=C4) C (=O) C5=CC=NC=C5) N6C7=CC=CC=C7C8=CC=CC=C86. InChI=1S/C36H23N3O/c40-36 (24-17-19-37-20-18-24)25-21-26 (38-32-13-5-1-9-28 (32)29-10-2-6-14-33 (29)38)23-27 (22-25)39-34-15-7-3-11-30 (34)31-12-4-8-16-35 (31)39/h1-23H. NPPBNNHLNOHWOA-UHFFFAOYSA-N. | |
| MDCK Transfection Reagent | Transfection Reagent for MDCK Kidney Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6846. | Nevada, Texas, USA |
| M-Dichloropyrazine | Heterocyclics. Alternative Names: 2,6-Dichloro-1,4-diazine. CAS No. 4774-14-5. Mole weight: 148.98. Purity: 95%+. IUPACName: 2,6-Dichloropyrazine. Canonical SMILES: C1=C(N=C(C=N1)Cl)Cl. Density: 1.6445 g/mL at 25 °C(lit.). | |
| Mdivi 1 | Mdivi 1. Group: Biochemicals. Grades: Purified. CAS No. 338967-87-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Mdivi-1 | Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Synonyms: Mdivi-1; Mdivi 1; Mdivi1; Mitochondrial Division Inhibitor 1. Grades: >98%. CAS No. 338967-87-6. Molecular formula: C15H10Cl2N2O2S. Mole weight: 353.22. | |
| Mdivi-1 | Mdivi-1 Inhibitor. Uses: Scientific use. Product Category: T1907. CAS No. 338967-87-6. |  |
| Mdivi-1 | Mdivi-1 is a selective dynamin-related protein 1 ( Drp1 ) inhibitor. Mdivi-1 is a mitochondrial division/ mitophagy inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mitochondrial division inhibitor 1. CAS No. 338967-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15886. | |
| MDK19922 | MDK19922, also known as NOD-IN-1 or Compound 4, is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 (IC50= 5.74 μM) and NOD2(IC50= 6.45 μM). Synonyms: ethyl 1-tosyl-1H-indole-2-carboxylate; NOD-IN-1, compound 4; MDK19922; MDK 19922; MDK-19922. CAS No. 132819-92-2. Molecular formula: C18H17NO4S. Mole weight: 343.39. | |
| MDK30165 | MDK30165, also known as K-Ras(G12C) Inhibitor 6, is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. This compound has potential therapeutic application for diseases related to Ras signaling. Synonyms: N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide; K-Ras(G12C) Inhibitor 6; MDK30165; MDK-30165; MDK 30165. CAS No. 2060530-16-5. Molecular formula: C17H22Cl2N2O3S. Mole weight: 405.33. | |
| MDK34597 | MDK34597 is a PI3K inhibitor. Synonyms: MDK34597; MDK-34597; MDK 34597. PI3K inhibitor. PIK-inhibitors; 3-(8-Morpholin-4-yl-9-oxa-1,5,7-triaza-fluoren-6-yl)-phenylamine; 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)aniline. CAS No. 371934-59-7. Molecular formula: C19H17N5O2. Mole weight: 347.378. | |
| MDK35833 | MDK35833, also called as Oct3/4-inducer-1, is a potent Oct3/4-inducer, which enhances its transcriptional activity in diverse human somatic cells, implying the possible benefit from using this class of compounds in regenerative medicine. Oct3/4 is suggested to promotes neuronal differentiation of ES cells under neurogenesis-inducing conditions. Synonyms: 4-[(4-Fluorophenyl)methoxy]-benzeneacetonitrile; Oct3/4-inducer-1, MDK35833; MDK-35833; MDK 35833. CAS No. 1016535-83-3. Molecular formula: C15H12FNO. Mole weight: 241.26. | |
| MDK74978 | MDK74978 is a multi-kinase inhibitor. Synonyms: N- (2-Hydroxyethyl) -4- (6- (4- (trifluoromethoxy) phenylamino) pyrimidin-4-yl) benzamide; MDK74978; MDK-74978; MDK 74978. Multi-kinase inhibitor I. CAS No. 778274-97-8. Molecular formula: C20H17F3N4O3. Mole weight: 418.376. | |
| MDK-7553 | MDK-7553, also known as CD38 inhibitor 78c and Compound-78c, is a potent CD38 inhibitor. MDK-7553 has CAS#1700637-55-3, which was reported in J Med Chem. 2015 Apr 23;58(8):3548-71. For the convenience of scientific communication, we name it as MDK-7553. The last four digits of CAS# were used for its name. Group: Inhibitors. Alternative Names: CD38 inhibitor 78c; Compound-78c; CD38i_78c; 78c; Cluster of Differentiation 38 Inhibitor; MDK-7553; MDK 7553; MDK7553; CD38-IN-78c; CD38 IN-78c; CD38IN-78c; CD38 inhibitor 78c. CAS No. 1700637-55-3. Molecular formula: C22H27N3O3S. Mole weight: 413.54. Appearance: Solid powder. Purity: >98%. IUPACName: 4-(((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)amino)-1-methyl-6-(thiazol-5-yl)quinolin-2(1H)-one. Canonical SMILES: O=C1N (C)C2=C (C=C (C3=CN=CS3)C=C2)C (N[C@H]4CC[C@H] (OCCOC)CC4)=C1. Catalog: ACM1700637553. | |
| MDL 100009 | MDL 100009 is the S-enantiomer of MDL 100151, which is a selective 5-HT2A antagonist. Synonyms: MDL 100009; MDL100009; MDL-100009; (S)-(2,3-Dimethoxyphenyl){1-[2-(4-fluorophenyl)ethyl]-4-piperidinyl}methanol. Grades: 99%. CAS No. 175673-57-1. Molecular formula: C22H28FNO3. Mole weight: 373.46. | |
| MDL 100151 | MDL 100151 is the racemic MDL 100907 and a selective 5-HT2A antagonist. Synonyms: MDL 100151; MDL-100151; MDL100151; (2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol. Grades: 99%. CAS No. 139290-69-0. Molecular formula: C22H28FNO3. Mole weight: 373.46. | |
| MDL 100907 | MDL 100907. Group: Biochemicals. Grades: Purified. CAS No. 139290-65-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL 100907 | MDL 100907 is a selective 5-HT2A receptor antagonist with Ki value of 0.36 nM. It shows antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo. Synonyms: Volinanserin; MDL-100907; MDL 100907; MDL100907; (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol; Volinanserin. Grades: ≥98% by HPLC. CAS No. 139290-65-6. Molecular formula: C22H28FNO3. Mole weight: 373.46. | |
| MDL 105519 | MDL 105519, a ligand selective for the glycine binding site of NMDA receptor, was shown that completely inhibited the binding of [3H]glycine to rat brain membranes with a Ki= 10.9±1.4 nM (n= 6). Inhibits [3H]glycine binding to the NMDA receptor with Kd= 3. Synonyms: MDL-105519; MDL 105519; MDL105519; MDL105,519; MDL-105,519; MDL 105,519; 3-[(E)-2-carboxy-2-phenylethenyl]-4,6-dichloro-1H-indole-2-carboxylic acidMDL 105,519Mdl 105519CHEMBL180427(E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid161230-88-2MDL-105519Lopac-M-216AC1O7G4OM216_SIGMALopac0_000805C1 8H. CAS No. 161230-88-2. Molecular formula: C18H11Cl2NO4. Mole weight: 376.19. | |
| MDL 11939 | MDL 11939 is a selective 5-HT2A receptor antagonist. MDL 11939 has anti-arrhythmic activity in anesthetized dogs following myocardial infarction. Synonyms: Glemanserin; MDL 11,939; Mdl 11939; α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol. Grades: ≥99% by HPLC. CAS No. 107703-78-6. Molecular formula: C20H25NO. Mole weight: 295.42. | |
| MDL 11,939 | MDL 11,939. Group: Biochemicals. Grades: Purified. CAS No. 107703-78-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL12330A | MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMI12330A. CAS No. 40297-09-4. Pack Sizes: 5 mg. Product ID: HY-103192. | |
| MDL 12330A hydrochloride | MDL 12330A hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 40297-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL 12330A hydrochloride | MDL 12330A is an adenylyl cyclase inhibitor. It can also inhibit cAMP and cGMP phosphodiesterases, and block slow extracellular and store-operated Ca2+ entry into cells. MDL 12330A can be used to investigate the role of the adenylyl cyclase/cAMP signaling pathway. Synonyms: MDL-12330A; MDL 12330A; MDL12330A; MDL-12330-A; MDL 12330 A; (±)-N-[(1R*,2R*)-2-Phenylcyclopentyl]-azacyclotridec-1-en-2-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 40297-09-4. Molecular formula: C23H36N2.HCl. Mole weight: 377.01. | |
| MDL 201012 | MDL 201012 is a selective M3 muscarinic receptor antagonist used as an antimuscarinic agent. Uses: Antimuscarinic agent. Synonyms: MDL 201012; MDL201012; MDL-201012; 1-cyclobutyl-7-(dimethylamino)-1-hydroxy-1-phenylhept-5-yn-2-one; 5-Heptyn-2-one,1-cyclobutyl-7-(dimethylamino)-1-hydroxy-1-phenyl-, hydrochloride, (-)-. Grades: 98%. CAS No. 136722-45-7. Molecular formula: C19H25NO2. Mole weight: 299.41. | |
| MDL 28170 | MDL 28170. Group: Biochemicals. Alternative Names: [ (1S) -1-[[ (1-Formyl-2-phenylethyl) amino]carbonyl]-2-methylpropyl]carbamic Acid Phenylmethyl Ester; Calp III; Calpain Inhibitor III. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 25mg. Molecular Formula: C22H26N2O4, Molecular Weight: 382.45. US Biological Life Sciences. | Worldwide |
| MDL 28170 | MDL 28170 is a calpain and cathepsin B inhibitor with Ki values of 10 and 25 nM respectively. It shows neuroprotective effects in vivo. MDL 28170 can attenuate depression in myocardial contractile performance which occurs during reperfusion following cardiac ischemia. Synonyms: benzyl N-[(2S)-3-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]butan-2-yl]carbamate. Grades: ≥ 95 % by HPLC. CAS No. 88191-84-8. Molecular formula: C22H26N2O4. Mole weight: 382.45. | |
| MDL-28170 | MDL-28170 (Calpain Inhibitor III) is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration [1] [2]. MDL-28170 also block γ-secretase [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain Inhibitor III. CAS No. 88191-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18236. | |
| MDL 28170, Z-Val-Phe-CHO, (Carbobenzoxy-valinyl-phenylalaninal, Calpain Inhibitor III) | A potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25nm respectively). MDL 28170 does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Modulates the formation of Ab formation by inhibiting the formation of intermediate Ab46 and protecting Ab from degradation. Group: Biochemicals. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL 29913 | MDL 29913 is a selective NK2 tachykinin receptor antagonist which can be used in the treatment of IBS. Synonyms: MDL 29913; MDL29913; MDL-29913; 1,4,7,10,13,16-Hexaazacyclooctadecane, Cyclic Peptide Deriv.; N-(2-Amino-4-methylpentyl)?-N-methyl-L-leucyl-L-glutaminyl-L-tryptophyl-L-phenylalanylglycine (5?1)?-Lactam. Grades: >97%. CAS No. 135721-56-1. Molecular formula: C40H56N8O6. Mole weight: 744.92. | |
| MDL 29,913 | MDL 29,913. Group: Biochemicals. Grades: Purified. CAS No. 135721-56-1. Pack Sizes: 200ug. US Biological Life Sciences. | Worldwide |
| MDL 29951 | MDL-29951 is a novel glycine antagonist of NMDA receptor activation, with Ki of 0.14 μM for [3H]glycine binding in vitro and in vivo. Synonyms: MDL 29951; MDL-29951; MDL29951; MDL 29,951; MDL-29,951; MDL29,951. CAS No. 130798-51-5. Molecular formula: C12H9Cl2NO4. Mole weight: 302.107. | |
| MDL 29951 | MDL 29951. Group: Biochemicals. Alternative Names: 2-Carboxy-4,6-dichloro-1H-Indole-3-propanoic Acid. Grades: Highly Purified. CAS No. 130798-51-5. Pack Sizes: 250mg. Molecular Formula: C12H9Cl2NO4, Molecular Weight: 302.11. US Biological Life Sciences. | Worldwide |
| MDL 72222 | MDL 72222. Group: Biochemicals. Grades: Purified. CAS No. 40796-97-2. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| MDL 72222 | MDL 72222 is a 5-HT3 receptor antagonist. Synonyms: MDL72222; MDL 72222; MDL-72222; Tropanyl 3,5-dichlorobenzoate; Bemesetron; endo-3,5-Dichloro-benzoic Acid 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester. Grades: ≥99% by HPLC. CAS No. 40796-97-2. Molecular formula: C15H17Cl2NO2. Mole weight: 314.21. | |
| MDL-72274 HCl | MDL-72274 is a selective SSAO inhibitor. It is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. MDL-72974 can be used for the treatment of Parkinson diseases. Uses: Parkinson diseases. Synonyms: MDL72274; MDL-72274; MDL 72274; MDL72274A; MDL-72274A; MDL 72274A; MDL72274 HCl; (E)-3-chloro-2-phenylprop-2-en-1-amine hydrochloride. Grades: 98%. CAS No. 85278-24-6. Molecular formula: C9H11Cl2N. Mole weight: 204.09. | |
| MDL 72527 | MDL 72527 is a polyamine oxidase inhibitor. It can block the production of H2O2 and increase the cells survival. MDL 72527 shows anticancer and neuroprotective activity in vivo. Synonyms: MDL 72527; MDL72527; MDL-72527; N1,N4-Di-2,3-butadienyl-1,4-butanediamine dihydrochloride. Grades: ≥95% by HPLC. CAS No. 93565-01-6. Molecular formula: C12H20N2.2HCl. Mole weight: 265.23. | |
| MDL 72527 | MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93565-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100621. | |
| MDL 72527 | MDL 72527. Group: Biochemicals. Grades: Purified. CAS No. 93565-01-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL 72832 hydrochloride | MDL 72832 hydrochloride is a potent ligand at 5-HT1A receptors, with mixed agonist and antagonist properties. Synonyms: MDL 72832 hydrochloride; MDL72832 hydrochloride; MDL-72832 hydrochloride; 8-[4-(1,4-Benzodioxan-2-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grades: ≥99% by HPLC. CAS No. 113777-40-5. Molecular formula: C22H30N2O4.HCl. Mole weight: 422.95. | |
| MDL 72832 hydrochloride | MDL 72832 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 113777-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL 73005EF hydrochloride | MDL 73005EF hydrochloride is a 5-HT1A receptor antagonist. Synonyms: MDL 73005EF hydrochloride; MDL73005EF hydrochloride; MDL-73005EF hydrochloride; 8-[2-(1,4-Benzodioxan-2-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grades: ≥98% by HPLC. CAS No. 102908-60-1. Molecular formula: C20H26N2O4.HCl. Mole weight: 394.9. | |
| MDL 73005EF hydrochloride | MDL 73005EF hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102908-60-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MDL 74156 | Heterocyclic Organic Compound. Alternative Names: MDL 74156. CAS No. 127951-99-9. Catalog: ACM127951999. | |
| MDM2 Antagonist IV, Nutlin-3a ((-)-4-(4,5-bis-(4-Chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazole-1-carbonyl)piperazine-2-one) | A cell-permeable and highly potent active enantiomer of Nutlin-3 that binds to the p53-binding pocket and blocks the interaction of p53 and MDM2 (IC50=90nM). Exhibits over 150-fold greater affinity for MDM2 than its less active enantiomer, Nutlin-3b. Induces p53 mediated apoptosis by both transcription-dependent and independent mechanisms. Shown to greatly potentiate the cytotoxic effects of chemotherapeutic agents and reduce tumor burden in vivo. Also shown to overcome ATM-mediated resistance to fludarabine in chronic lymphocyte leukemia. Cells treated with Nutlin-3a permanently lose their ability to proliferate and enter into a pattern of permanent senescence. Mouse embryonic fibroblasts with p53+/+ MEFs show significantly reduced reprogramming capabilities following Nutlin-3a treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 675576-98-4. Pack Sizes: 5mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
| MDM2 Inhibitor VII, MEL23 (3-Butyl-6-hydroxy-5-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pyrimidine-2,4(1H,3H)-dione, MDM2-MDMX E3 Ligase Inhibitor) | A cell-permeable tetrahydro-b-carbolinylbarbiturate compound that selectively inhibits the E3 ligase activity of Mdm2-MdmX hetero-complex over that of Mdm2-Mdm2 homo-complex (70.6% vs. 17.6% inhibition, respectively, at 100uM), without affecting Mdm2-MdmX complex formation or the activity of two other UbcH5C-utilizing ligase complexes Roc1-Cul1 and BRCA1-BARD1. Effectively inhibits ubiquitination and proteasomal degradation of cellular Mdm2 and p53 (effective conc.=14uM in U2OS, RKO, and HCT116 cultures) and induce RKO and MEF cell death in a p53- and Mdm2-dependent manner. Unlike Nutlin-3, MEL23 does not interfere with Mdm2-p53 interaction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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