A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
MC 1443. Group: Biochemicals. Alternative Names: 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole. Grades: Highly Purified. CAS No. 163239-22-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H11FN2. US Biological Life Sciences.
Worldwide
MC1568
MC1568 is an impressive and discerning inhibitor extensively employed in the research of a wide array of ailments such as cancer, neurodegeneration and inflammatory maladies. Synonyms: MC-1568; MC 1568; MC1568. CAS No. 852475-26-4. Molecular formula: C17H15FN2O3. Mole weight: 314.311.
MC 1568
A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Group: Biochemicals. Alternative Names: 3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide. Grades: Highly Purified. CAS No. 852475-26-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
MC 1742
MC 1742 is a novel and selective HDAC inhibitor with potential anticancer activity (IC50= 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 and HDAC8, respectively). Histone deacetylase inhibitor has been shown to induce growth arrest, apoptosis and differentiation in sarcoma cancer stem cells. Synonyms: MC-1742; MC 1742; MC1742; 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide. Grades: ≥98% by HPLC. CAS No. 1776116-74-5. Molecular formula: C21H21N3O3S. Mole weight: 395.47.
MC180295
MC180295 is a potent and selective CDK9-Cyclin T1 inhibitor with IC50 of 5 nM. MC180295 also inhibits GSK-3α and GSK-3&beta. It has a powerful anti-tumor effect. Grades: ≥98% by HPLC. CAS No. 2237942-08-2. Molecular formula: C17H18N4O3S. Mole weight: 358.4.
MC70 is a potent and selective modulator of P-glycoprotein(P-gp) with EC50 value of 0.69 μM. It is also an inhibitor of the ABC transporter ABCB1 (aka MDR1). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics. Uses: Mc70 is potential to be used as novel anticancer agent. Synonyms: MC-70; MC 70; MC70. 4-[4-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol;MC-70;4'-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-[1,1'-biphenyl]-4-ol. Grades: >98 %. CAS No. 1031367-64-2. Molecular formula: C24H25NO3. Mole weight: 375.47.
MC70
MC70 is a potent and non-selective P-glycoprotein (P-gp) inhibitor with an EC 50 of 0.69 μM. MC70 is an ABC transporters inhibitor and anticancer agent. MC70 interacts with ABCB1, ABCG2 and ABCC1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031367-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113805.
MC70 hydrochloride
MC70 hydrochloride is the hydrochloride salt form of MC70, which is a potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics. Uses: Anticancer agent. Synonyms: MC70 hydrochloride; MC 70 hydrochloride; MC-70 hydrochloride; 4-[4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol hydrochloride. Grades: 98%. Molecular formula: C24H25NO3.HCl. Mole weight: 411.92.
MC 976
Calcipotriol Impurity 3 is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: MC 976; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-5-cyclopropyl-5-hydroxypentan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol. Grades: >98%. CAS No. 129831-99-8. Molecular formula: C27H42O3. Mole weight: 414.63.
MCA
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62935-72-2. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W027544.
MC-AAA-NHCH2OCH2COOH
MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414594-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132159.
Mca-Ala-Pro-Lys(Dnp)-OH
Mca-Ala-Pro-Lys(Dnp)-OH, a FRET substrate for angiotensin-converting enzyme 2 (ACE2), is used to monitor enzyme activity in plasma, urine, heart and lungs. Synonyms: Mca-APK(Dnp); L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine; (S)-6-((2,4-dinitrophenyl)amino)-2-((S)-1-((S)-2-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamido)propanoyl)pyrrolidine-2-carboxamido)hexanoic acid. Grades: ≥95%. CAS No. 305336-82-7. Molecular formula: C32H36N6O12. Mole weight: 696.67.
Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide
Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide, a fluorescent (FRET) peptide substrate containing the wild-type amyloid precursor protein (APP) β-secretase cleavage site, is used to determine the β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). TOP is a potential β-secretase candidate and is involved in APP processing in vivo. Synonyms: Mca-APP770 (667-676)-Lys(Dnp)-Arg-Arg amide; Mca-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2; Mca-SEVKMDAEFRK(Dnp)RR-amide. Grades: ≥95% by HPLC. CAS No. 1802078-33-6. Molecular formula: C87H129N27O28S. Mole weight: 2033.21.
Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp)
Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) is a pro-memapsin-2 fluorogenic substrate (FRET) containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF. Synonyms: Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp); Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine; L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-. Grades: ≥95%. CAS No. 1802078-31-4. Molecular formula: C68H88N14O27. Mole weight: 1533.53.
Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide
Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide is a fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP. Its kinetic parameters at pH 4.5 are Km = 4.5 μM and kcat = 0.25 min-1. Synonyms: Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp) amide; Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-NH2; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysinamide; L-Lysinamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-; Mca-SEVNLDAEFK(Dnp) amide. Grades: ≥95%. CAS No. 1802078-32-5. Molecular formula: C68H89N15O26. Mole weight: 1532.54.
Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2, a FRET substrate for cathepsin D and E, is also cleaved by napsin A. Synonyms: MOCAc-GKPILFFRL-{Lys(Dnp)}-{D-Arg}-NH2; Mca-GKPILFFRL-Dpa-r-amide; MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-{Lys(Dnp)}-{D-Arg}-NH2; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-(2,4-dinitrophenyl)-L-lysyl-D-argininamide; D-Argininamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-(2,4-dinitrophenyl)-L-lysyl-; Cathepsin D and E FRET Substrate. Grades: ≥90%. CAS No. 839730-93-7. Molecular formula: C85H122N22O19. Mole weight: 1756.01.
Used for in vitro transcription of 5'-capped mRNA to generate Cap 0 structure. mCAP has a 50% chance of inserting in the right direction to enhance translation. Another 50% of the molecules cannot become effective translation substrates, which reduces the specific activity of the transcript. Synonyms: m7G(5')ppp(5')G Cap Analog; N7-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine; 7-Methyl-guanosine-5'-triphosphate-5'-guanosine; M7-GpppG. Grades: ≥90% by AX-HPLC. Molecular formula: C21H30N10O18P3 (free acid). Mole weight: 803.44 (free acid).
m-Carborane
m-Carborane. Group: Biochemicals. Alternative Names: 1, 7-Dicarbadodecaborane (12). Grades: Highly Purified. CAS No. 16986-24-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C2H12B10. US Biological Life Sciences.
m-Carborane-1-carboxylic Acid is used as a reactant or reagent in the synthetic preparation of ortho-carbaborane indomethacin pharmacophores as selective COX-2 enzyme inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 18581-81-2. Pack Sizes: 15mg, 30mg. Molecular Formula: C3H12B10O2, Molecular Weight: 188.24. US Biological Life Sciences.
Histone deacetylase inhibitor II. A cell-permeable second generation hybrid polar agent that inhibits HDAC activity. Inhibition is believed to arise as a result of the binding of the hydroxamic moiety to the active site zinc. Induces apoptosis and Fas/Fas ligand expression in human neuroblastoma. Group: Biochemicals. Alternative Names: N-Hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]benzamide; CBHA. Grades: Highly Purified. CAS No. 174664-65-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Mca-SEVNLDAEFK(Dnp)-NH2
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1802078-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4920.
MCA-SEVNLDAEFR-K(Dnp)-RR, amide
It is a FRET-based substrate. Synonyms: Mca-(Asn670, Leu671)-APP770(667-676)-Lys(Dnp)-Arg-Arg amide; MCA-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2; Mca-(Asn670, Leu671)-Amyloid beta/A4 Protein Precursor770(667-676)-Lys(Dnp)-Arg-Arg amide. Grades: ≥95%. CAS No. 438625-61-7. Molecular formula: C86H125N27O29. Mole weight: 2001.08.
MCB-613
MCB-613 is a potent Steroid receptor coactivator SRC small molecule ‘stimulator (SMS), super-stimulates SRCs transcriptional activity. MCB-613 increases SRCs interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species ( ROS ). MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1162656-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19625.
MCB-613
MCB-613 is a potent steroid receptor coactivator (SRC) stimulator. Synonyms: MCB 613; MCB613. Grades: 98%. CAS No. 1162656-22-5. Molecular formula: C20H20N2O. Mole weight: 304.39.
m-CBP
Phosphorescent host material and TADF emitter in OLEDs. Group: Organic light-emitting diode (oled) materials. Alternative Names: 3,3'-Di(9H-carbazol-9-yl)-1,1'-biphenyl. CAS No. 342638-54-4. Product ID: 9-[3-(3-carbazol-9-ylphenyl)phenyl]carbazole. Molecular formula: 484.59. Mole weight: C36H24N2. C1=CC=C2C (=C1)C3=CC=CC=C3N2C4=CC=CC (=C4)C5=CC (=CC=C5)N6C7=CC=CC=C7C8=CC=CC=C86. InChI=1S/C36H24N2/c1-5-19-33-29 (15-1)30-16-2-6-20-34 (30)37 (33)27-13-9-11-25 (23-27)26-12-10-14-28 (24-26)38-35-21-7-3-17-31 (35)32-18-4-8-22-36 (32)38/h1-24H. NSXJEEMTGWMJPY-UHFFFAOYSA-N.
MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104676-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132251.
MCC-555
MCC-555, a thiazolidinedion derivative, has been found to be a PPAR agonist that was once studied as hyperglycaemic and hyperlipidaemic. The Phase II trial against Type-2 diabetes mellitus has been already discontinued. Synonyms: Netoglitazone; MCC-555; MCC 555; MCC555; RWJ-241947; RWJ 241947; RWJ241947; isaglitazone; Netoglitazone; UNII-QOV2JZ647A; 5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione. Grades: 98%. CAS No. 161600-01-7. Molecular formula: C21H16FNO3S. Mole weight: 381.42.
MCC950
MCC950, also called as CP-456773 or CRID3, is a small molecule that selectively inhibits activation of NLRP3 but does not inhibit NLRC4, AIM2, TLR2 signaling, or priming of NLRP3. MCC950 can be used to treat inflammatory diseases. Synonyms: MCC-950; MCC 950; CP-456773. CAS No. 210826-40-7. Molecular formula: C20H24N2O5S. Mole weight: 404.48.
MCC950
MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773; CRID3. CAS No. 210826-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12815.
MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773 sodium; CRID3 sodium salt. CAS No. 256373-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12815A.
MCdef
MCdef is a defensin-like peptide detected in hemocytes of Manila clams (Ruditapes philippinarum). MCdef showed highest activity against Streptococcus iniae and Staphylococcus aureus.
MC-DOXHZN hydrochloride
MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride. CAS No. 480998-12-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16261B.
MCD Peptide
22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with potent convulsant activity. Synonyms: Peptide 401; Mast Cell Degranulating (MCD) Peptide; Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2 (Disulfide bridge: Cys3-Cys15, Cys5-Cys19); L-isoleucyl-L-lysyl-L-cysteinyl-L-asparagyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinyl-glycyl-L-lysyl-L-asparaginamide (3->15),(5->19)-bis(disulfide). Grades: ≥95%. CAS No. 32908-73-9. Molecular formula: C110H192N40O24S4. Mole weight: 2587.22.
MCF-7 Transfection Reagent
Transfection Reagent for MCF7 Breast Cancer Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1766.
Nevada, Texas, USA
MC-Gly-Gly-Phe-Gly
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs). Synonyms: (S)-5-Benzyl-18-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecan-1-oic acid. Grades: >98.0%. CAS No. 2413428-36-9. Molecular formula: C25H31N5O8. Mole weight: 529.54.
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl]-. Grades: >98.0%. CAS No. 1599440-25-1. Molecular formula: C28H36N6O10. Mole weight: 616.62.
MCHB-1
MCHB-1 is a potent and selective agonist of the human cannabinoid 2 (CB2) receptor with Ki values of 3.7 and 110 nM for CB2 and CB1, respectively. Synonyms: N-Methylcyclohexyl benzimidazole analog 1; 1-(cyclohexylmethyl)-2-(4-ethoxybenzyl)-N,N-diethyl-1h-benzo[d]imidazole-5-carboxamide; 2-(4-ethoxybenzyl)-1-(cyclohexylmethyl)-N,N-diethyl-1H-benzo[d]imidazole-5-carboxamide. Grades: ≥98%. CAS No. 1046140-32-2. Molecular formula: C28H37N3O2. Mole weight: 447.6.
MCH (human, mouse, rat)
MCH (human, mouse, rat). Group: Biochemicals. Grades: Purified. CAS No. 128315-56-0. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
MCH (human, mouse, rat)
MCH is an endogenous melanin-concentration hormone receptor agonist with IC50 values of 0.3 and 1.5 nM at MCH1 and MCH2 receptors respectively. It can increase food intake in vivo. Synonyms: Melanin concentrating hormone, human, mouse, rat; Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val. Grades: ≥95% by HPLC. CAS No. 128315-56-0. Molecular formula: C105H160N30O26S4. Mole weight: 2386.84.
m-Chloramphenicol erythro form
m-Chloramphenicol erythro form is an impurity of Chloramphenicol. Chloramphenicol is an antibiotic used for the treatment of a number of bacterial infections. Synonyms: M-erythro-Chloramphenicol. CAS No. 138125-71-0. Molecular formula: C11H12Cl2N2O5. Mole weight: 323.126.
m-Chloramphenicol threo form
m-Chloramphenicol threo form is an impurity of Chloramphenicol. Chloramphenicol is an antibiotic used for the treatment of a number of bacterial infections. Synonyms: M-threo-Chloramphenicol. CAS No. 7411-65-6. Molecular formula: C11H12Cl2N2O5. Mole weight: 323.126.
m-Chloro Hippuric Acid
m-Chloro Hippuric Acid. Group: Biochemicals. Alternative Names: (3-Chlorobenzoylamino) acetic Acid; N-(3-Chlorobenzoyl)glycine; NSC 201882; m-Chlorohippuric Acid; N-(3-Chlorobenzoyl)glycine. Grades: Highly Purified. CAS No. 57728-59-3. Pack Sizes: 1g. Molecular Formula: C9H8ClNO3, Molecular Weight: 218.62. US Biological Life Sciences.
m-Chlorophenylbiguanide hydrochloride is the hydrochloride salt of chlorophenylbiguanide, which is a selective and prototypical potent 5-HT3 serotonin receptor agonist. Synonyms: 1-(3-Chlorophenyl)biguanide hydrochloride; 1-(m-Chlorophenyl)biguanide hydrochloride; N-(3-Chlorophenyl)imidodicarbonimidic diamide hydrochloride; m-CPBG hydrochloride; Imidodicarbonimidic diamide, N-(3-chlorophenyl)-, hydrochloride (1:1); Biguanide, 1-(m-chlorophenyl)-, monohydrochloride; Imidodicarbonimidic diamide, N-(3-chlorophenyl)-, monohydrochloride; N-m-Chlorophenylbiguanide hydrochloride. Grades: ≥98% by HPLC. CAS No. 2113-5-5. Molecular formula: C8H11Cl2N5. Mole weight: 248.11.
m-Chlorophenylbiguanide hydrochloride
m-Chlorophenylbiguanide hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 2113-5-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
MCHr1 antagonist 1
A selective antagonist of melanin concentrating hormone-1 (MCH1) receptor. Synonyms: 5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester. CAS No. 391610-37-0. Molecular formula: C28H33F2N5O5. Mole weight: 557.59.
MCI826
MCI-826 potently antagonized LTD4- and LTE4-induced contractions at extremely low concentrations in the isolated guinea pig trachea with pA2 values of 8.3 and 8.9, respectively, on a molar basis. Synonyms: 2,2-diethyl-4-oxo-4-[3-[(E)-2-(4-propan-2-yl-1,3-thiazol-2-yl)ethenyl]anilino]butanoic acid; 2, 2-diethyl-3'- (2- (2- (4-isopropyl) thiazolyl) ethenyl) succinanilic acid; MCI 826; MCI 826, (E)- isomer; MCI-826. CAS No. 140646-80-6. Molecular formula: C22H28N2O3S. Mole weight: 400.53.
MCL 0020
MCL 0020. Group: Biochemicals. Grades: Purified. CAS No. 475498-26-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MCL 0020
MCL 0020 is a selective melanocortin MC4 receptor antagonist with IC50 value of 11.63nM at MC4 receptor. It shows anxiolytic-like activity in vivo. Synonyms: MCL 0020; MCL0020; MCL-0020; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide. Grades: >98%. CAS No. 475498-26-1. Molecular formula: C34H39N7O4. Mole weight: 609.73.
MCL-1/BCL-2-IN-2
MCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163793-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129700.
MCL-1/BCL-2-IN-3
MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC 50 s of 5.95 and 4.78 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163793-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129701.
Mcl1-IN-1
Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 ( Mcl-1 ) ( IC 50 =2.4 μM). Uses: Scientific research. Group: Signaling pathways. CAS No. 713492-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16669.
Mcl1-IN-1
Mcl1-IN-1 is a potent Mcl-1-selective inhibitor with IC50 of 2.4 uM, relative to the related Bcl-2 family protein Bcl-xL. Uses: Myeloid cell factor 1 inhibitor. Synonyms: Mcl1-IN-1; Mcl1IN1; Mcl1 IN 1; Mcl1-inhibitor-1; Mcl1 inhibitor 1; {2-[(5-Chloro-8-hydroxy-7-quinolinyl)(2-pyridinylamino)methyl]phenoxy}acetic acid. Grades: ≥95%. CAS No. 713492-66-1. Molecular formula: C23H18ClN3O4. Mole weight: 435.86.
A cell-permeable thiazolyl iminopyrogallol that selectively neutralizes Mcl-1, but not Bcl-XL, antiapoptotic activity by directly targeting Mcl-1 BH3-binding site, effectively competing against Bid BH3 sequence for Mcl-1 binding (IC50 = 4.8uM). Shown to induce caspase 3/7 activation and cell death in Mcl-1-, but not Bcl-XL-, dependent B-ALL cultures (6% vs. 82% survival, respectively; 10uM). In comparison, ABT-737 affects only Bcl-XL-, but not Mcl-1-, dependent B-ALL cells. Neither MIM1 nor ABT-737 significantly affects the survival of wild-type or Bax-/-Bak-/- MEF. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
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MCLA hydrochloride
MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide. Uses: Scientific research. Group: Fluorescent dye. CAS No. 128322-44-1. Pack Sizes: 5 mg. Product ID: HY-W013275.
MCM-22
MCM-22. Group: Mcm-22. CAS No. 12173-28-3. Pack Sizes: 20 g.
MCM-41
MCM-41. Group: Mcm-41. CAS No. 12173-28-3. Pack Sizes: 50 g.