A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Maximin S5 has antibacterial activity. The source of Maximin S5 is Bombina maxima [Giant fire-bellied toad]. Grades: >97% by HPLC. Molecular formula: C87H139N23O26S2. Mole weight: 1987.30.
Maximin-y
Maximin-y shows antimicrobial activity against bacteria and against the fungus C.albicans. It has little hemolytic activity.
Maximin y type 2 precursor
Maximin y type 2 precursor has antibacterial and antifungal activity. The source of Maximin y type 2 precursor is Bombina maxima [Giant fire-bellied toad]. Grades: >95% by HPLC.
Maximin-z
Maximin-z has antibacterial and antifungal activities. Maximin-z was found in Bombina maxima.
MaxiPost
MaxiPost. Group: Biochemicals. Grades: Purified. CAS No. 187523-35-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 153858. CAS No. 35846-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13674.
Maytansinoid DM4
Maytansinoid DM4 is a cytotoxic agent. It is used as a antibody-drug conjugate that has a potential to treat cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 799840-96-3. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C39H56ClN3O10S, Molecular Weight: 794.39. US Biological Life Sciences.
Worldwide
Maytansinoid DM4
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N2'-deacetyl-n2'-(4-Mercapto-4-Methyl-1-oxopentyl)-6-MethylMaytansine. Grades: ≥98.0% (HPLC). CAS No. 799840-96-3. Molecular formula: C39H56ClN3O10S. Mole weight: 780.37.
Maytansinol
Maytansinol. Group: Biochemicals. Alternative Names: 3-O-De[2-[methyl(acetyl)amino]-1-oxopropyl]maytansine. Grades: Highly Purified. CAS No. 57103-68-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C28H37ClN2O8. US Biological Life Sciences.
Worldwide
MAZ51
MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. MAZ51 inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. MAZ51 had no effect on ligand-induced autophosphorylation of EGFR, IGF-1R and PDGFR?. MAZ51 blocks proliferation and induces apoptosis in a wide variety of tumor cells. Antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 163655-37-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116624.
MAZ51
MAZ51 is an indolinone that blocks the ligand-induced autophosphorylation of VEGFR-3 by VEGF-C. It was shown to inhibit proliferation and induce apoptosis of tumor cell lines. Synonyms: (E)-3-((4-(dimethylamino)naphthalen-1-yl)methylene)indolin-2-one; 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one; EX-A1914. Grades: ≥95%. CAS No. 163655-37-6. Molecular formula: C21H18N2O. Mole weight: 314.4.
Mazdutide
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide ( GLP-1R ) and glucagon receptor ( GCGR ). Mazdutide binds human and mouse GCGR ( K i : 17.7 nM and 15.9 nM, respectively) and GLP-1R ( K i : 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets ( EC 50 : 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: IBI-362; LY-3305677; OXM-3. CAS No. 2259884-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3375.
Mazdutide
Mazdutide is a long-acting glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. Mazdutide has been use in the research of type 2 diabetes mellitus (T2DM). Synonyms: IBI362; IBI 362; IBI-362; LY3305677; LY 3305677; LY-3305677; OXM3; OXM-3; OXM 3. CAS No. 2259884-03-0. Molecular formula: C207H317N45O65. Mole weight: 4476.
Mazisotine
SSTR4 agonist-1 (Compound 47) is a selective agonist for somatostatin receptor subtype 4 ( SSTR4 ) with an EC 50 of 4.7 nM. SSTR4 agonist-1 reveals a half-life > 130 minutes in human liver microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638588-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139347.
MB05032
MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 261365-11-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16307.
MB05032
MB05032 is a FBPase inhibitor (IC50 = 16 ± 1.5 nM for human liver FBPase). It promotes hematopoietic stem cell and progenitor cell expansion. Synonyms: MB-05032; [5-(2-amino-5-isobutyl-1,3-thiazol-4-yl)-2-furyl]phosphonic acid. Grades: >98%. CAS No. 261365-11-1. Molecular formula: C11H15N2O4PS. Mole weight: 302.29.
MB06322
MB06322 (CS-917) is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis. CS-917 suppressed plasma glucose elevation after meal loading in a dose-dependent manner at doses ranging from 10 to 40 mg/kg. Research findings suggest that enhanced gluconeogenesis contributes to hyperglycemia in postprandial conditions as well as in fasting conditions, and that CS-917 as an FBPase inhibitor corrects postprandial hyperglycemia as well as fasting hyperglycemia. Synonyms: Managlinat dialanetil; MB 06322; MB-06322; CS-917; CS917; CS 917; diethyl 2, 2'-(((5-(2-amino-5-isobutylthiazol-4-yl)furan-2-yl)phosphanediyl)bis(azanediyl))(2S, 2'S)-dipropionate. CAS No. 280782-97-0. Molecular formula: C21H33N4O5PS. Mole weight: 484.55.
MB-07133
MB-07133 is a novel cytarabine (araC) prodrug. It uses the HepDirect technology to target production of the active form of araC, araC triphosphate (araCTP), to the liver. It has the potential to be both efficacious and well tolerated in HCC patients. It was developed by Ligand and in clinic phase 3 trials. Uses: Mb-07133 has the potential to be both efficacious and well tolerated in hcc patients. Synonyms: MB 07133; MB07133; 4-Imino-1-{5-O-[2-oxo-4-(pyridin-4-yl)-1,3,2lambda~5~-dioxaphosphinan-2-yl]pentofuranosyl}-1,4-dihydropyrimidin-2-ol. Grades: 98%. CAS No. 685111-92-6. Molecular formula: C17H21N4O8P. Mole weight: 440.34.
MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C , with a K d of 4.1?μM. MB710 shows anticancer activity in p53-Y220C cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230044-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120373.
Mbba
Mbba. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[(p-methoxybenzylidene)amino]-4-butylbenzene;1-butyl-4-[(p-methoxybenzylidene)amino]benzene;4'-methoxybenzylidiene-4-butylaniline;4-butyl-n-((4-methoxyphenyl)methylene)-benzeneamin;4-butyl-n-[(4-methoxyphenyl)methylene]-benzenamin;4-Butyl-N-[(4-methoxyp. Product Category: Organic & Printed Electronics. CAS No. 26227-73-6. Molecular formula: C18H21NO. Mole weight: 267.37. Purity: >98.0%(GC)(T). Product ID: ACM26227736. Alfa Chemistry ISO 9001:2015 Certified.
mBBr
mBBr. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Monobromobimane. Product Category: Other Fluorophores. Appearance: Yellow powder. CAS No. 71418-44-5. Molecular formula: C10H11BrN2O2. Mole weight: 271.11. Purity: 95%+. IUPACName: 7-(bromomethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione. Canonical SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C. Density: 1.66 ± 0.1 g/ml. Product ID: ACM71418445-1. Alfa Chemistry ISO 9001:2015 Certified.
mBCl
mBCl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Monochlorobimane. Product Category: Other Fluorophores. CAS No. 76421-73-3. Molecular formula: C10H11ClN2O2. Mole weight: 226.66. Purity: 95%+. IUPACName: 7-(chloromethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione. Canonical SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CCl)C. Product ID: ACM76421733-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: BENOMYL, MB A-Class.
MBCQ
MBCQ is an inhibitor of cGMP-specific phosphodiesterase (PDE5). Synonyms: 4-Quinazolinamine, N-(1,3-benzodioxol-5-ylmethyl)-6-chloro-. Grades: ≥98%. CAS No. 150450-53-6. Molecular formula: C16H12ClN3O2. Mole weight: 313.7.
MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole. CAS No. 33984-50-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-141667.
MBD-7
MBD-7 is isolated from Mus musculus (Mouse) and has bactericidal activity. Synonyms: Beta-defensin 7; BD-7; Defensin, beta 7.
m-Benzenedimethanol
Benzenedimethanol. CAS No. 626-18-6. Categories: 1,3-benzenedimethanol.
Pennsylvania PA
m-(Benzyloxy)benzyl Chloride
m-(Benzyloxy)benzyl Chloride. Group: Biochemicals. Alternative Names: 1-Benzyloxy-3-chloromethylbenzene; 3-(Benzyloxy)benzyl Chloride; Benzyl α-Chloro-m-tolyl Ether. Grades: Highly Purified. CAS No. 24033-03-2. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
MBMAP28
BMAP-28 has broad antimicrobial activities and confers protection in an animal model: mouse of bacterial infection or sepsis.
M(Boc) Acetic acid
A nucleobase for PNA synthesis. Synonyms: (6-tert-butoxycarbonylaminopyridin-3-yl) acetic acid. Grades: 98%. CAS No. 1256337-02-6. Molecular formula: C12H16N2O4. Mole weight: 252.27.
Mbo II
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme approximately 60% of the dna fragments can be ligated and recut. in presence of 10%peg ligation is better. Group: Restriction Enzymes. Purity: 200U; 1000U. GAAGA(N)8↑ CTTCT(N)7&darr. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Mbo II from Moraxella bovis. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1130RE.
MBP146-78
MBP146-78 is a potent and selective inhibitor of cGMP dependent protein kinases. Synonyms: MBP146-78; MBP146 78; MBP14678; 4-[2-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrrol-3-yl]pyridine; 4-(2-(4-fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl)pyridine; P-(FP)-MP-PP. CAS No. 188343-77-3. Molecular formula: C21H22FN3. Mole weight: 335.42.
MBP (85-99) peptide antagonist trifluoroacetate salt
m-BPDBT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,3'-Bis(dibenzo[b,d]thiophen-4-yl)-1,1'-biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1128045-14-6. Molecular formula: C36H22S2. Mole weight: 518.69 g/mol. Product ID: ACM1128045146. Alfa Chemistry ISO 9001:2015 Certified.
m-Bpye
m-Bpye. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Di(pyren-1-yl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1616657-81-8. Molecular formula: C38H22. Mole weight: 478.58 g/mol. Product ID: ACM1616657818. Alfa Chemistry ISO 9001:2015 Certified. Categories: M'Baye Niang.
m-BPySCz
m-BPySCz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3-(9H-Carbazol-9-yl)-phenyl)-3-(pyridine-3-yl)pyridine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2245948-99-4. Molecular formula: C28H19N3. Mole weight: 397.47 g/mol. Product ID: ACM2245948994. Alfa Chemistry ISO 9001:2015 Certified.
MBQ-167
MBQ-167 is a dual Rac/Cdc42 inhibitor with IC50 values of 103 nM and 78 nM respectively, in metastatic breast cancer cells. It decreases Rac and Cdc42 downstream effector p21-activated kinase (PAK) signaling and the activity of STAT3, without affecting Rho, MAPK, or Akt activities. Synonyms: HY-112842; CS-0066907; 9-ethyl-3-(5-phenyltriazol-1-yl)carbazole. CAS No. 2097938-73-1. Molecular formula: C22H18N4. Mole weight: 338.41.
MBQ-167
MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097938-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112842.
m-Bromobenzontitride
m-Bromobenzontitride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-bromoethoxy)-4-t-butylbenzene; p-(2-bromoethoxy)-tert-butylbenzene; 2-bromo-1-(4-tert-butylphenoxy)ethane; 1-[4-(tert-butyl)phenoxy]-2-bromoethane; bromoethylbutylphenylether; <2-Brom-aethyl>-<4-tert.-butyl-phenyl>-aether; 1-(2-bromoethox. Product Category: Heterocyclic Organic Compound. CAS No. 5952-59-6. Molecular formula: C12H17BrO. Mole weight: 257.167. Purity: 0.96. IUPACName: 1-(2-bromoethoxy)-4-tert-butylbenzene. Density: 1.225g/cm³. Product ID: ACM5952596. Alfa Chemistry ISO 9001:2015 Certified.
MBS
MBS. CAS No. 58626-38-3. Pack Sizes: Milligram Quantities: 100 mg. Order Number: CL202.
MBX-2982 is a selective, orally-available G protein-coupled receptor 119 ( GPR119 ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037792-44-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15291.
MBX-2982
MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. Synonyms: Pyrimidine, MBX-2982; MBX 2982; MBX2982; SAR-260093; SAR260093; SAR 260093; 5-ethyl-2-(4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-thiazolyl)-1-piperidinyl)-; 4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole; B5TRY67L51. Grades: 98%. CAS No. 1037792-44-1. Molecular formula: C22H24N8OS. Mole weight: 448.549.
MC-031
MC-031, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.6×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylchlorothricin. CAS No. 134637-04-0. Molecular formula: C49H61ClO16. Mole weight: 941.45.
MC-032
MC-032, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.5×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylhydroxychlorothricin. CAS No. 134615-17-1. Molecular formula: C49H61ClO17. Mole weight: 957.45.
MC-033
MC-033, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 1.06×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: MC 033; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-15-9. Molecular formula: C49H61ClO16. Mole weight: 941.45.
MC-034
MC-034, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 18.3×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: MC 034; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-2A-hydroxy-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-16-0. Molecular formula: C49H61ClO17. Mole weight: 957.45.
MC 1443
MC 1443. Group: Biochemicals. Alternative Names: 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole. Grades: Highly Purified. CAS No. 163239-22-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H11FN2. US Biological Life Sciences.
Worldwide
MC1568
MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor, used for cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 852475-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16914.
MC1568 is an impressive and discerning inhibitor extensively employed in the research of a wide array of ailments such as cancer, neurodegeneration and inflammatory maladies. Synonyms: MC-1568; MC 1568; MC1568. CAS No. 852475-26-4. Molecular formula: C17H15FN2O3. Mole weight: 314.311.
MC 1568
A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Group: Biochemicals. Alternative Names: 3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide. Grades: Highly Purified. CAS No. 852475-26-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
MC 1742
MC 1742 is a novel and selective HDAC inhibitor with potential anticancer activity (IC50= 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 and HDAC8, respectively). Histone deacetylase inhibitor has been shown to induce growth arrest, apoptosis and differentiation in sarcoma cancer stem cells. Synonyms: MC-1742; MC 1742; MC1742; 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide. Grades: ≥98% by HPLC. CAS No. 1776116-74-5. Molecular formula: C21H21N3O3S. Mole weight: 395.47.
MC180295
MC180295 is a potent and selective CDK9-Cyclin T1 inhibitor with IC50 of 5 nM. MC180295 also inhibits GSK-3α and GSK-3&beta. It has a powerful anti-tumor effect. Grades: ≥98% by HPLC. CAS No. 2237942-08-2. Molecular formula: C17H18N4O3S. Mole weight: 358.4.
MC70 is a potent and selective modulator of P-glycoprotein(P-gp) with EC50 value of 0.69 μM. It is also an inhibitor of the ABC transporter ABCB1 (aka MDR1). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics. Uses: Mc70 is potential to be used as novel anticancer agent. Synonyms: MC-70; MC 70; MC70. 4-[4-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol;MC-70;4'-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-[1,1'-biphenyl]-4-ol. Grades: >98 %. CAS No. 1031367-64-2. Molecular formula: C24H25NO3. Mole weight: 375.47.
MC70
MC70 is a potent and non-selective P-glycoprotein (P-gp) inhibitor with an EC 50 of 0.69 μM. MC70 is an ABC transporters inhibitor and anticancer agent. MC70 interacts with ABCB1, ABCG2 and ABCC1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031367-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113805.
MC70 hydrochloride
MC70 hydrochloride is the hydrochloride salt form of MC70, which is a potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics. Uses: Anticancer agent. Synonyms: MC70 hydrochloride; MC 70 hydrochloride; MC-70 hydrochloride; 4-[4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol hydrochloride. Grades: 98%. Molecular formula: C24H25NO3.HCl. Mole weight: 411.92.
MC 976
Calcipotriol Impurity 3 is a derivative of vitamin D3 and an analogue of calcipotriol. Calcipotriol is a synthetic derivative of calcitriol used for the treatment of psoriasis. Synonyms: MC 976; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-5-cyclopropyl-5-hydroxypentan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol. Grades: >98%. CAS No. 129831-99-8. Molecular formula: C27H42O3. Mole weight: 414.63.
MCA
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62935-72-2. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W027544.
MCA
MCA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Methoxycoumarin-4-acetic acid. Product Category: Other Fluorophores. CAS No. 62935-72-2. Molecular formula: C12H10O5. Mole weight: 234.2. Product ID: ACM62935722. Alfa Chemistry ISO 9001:2015 Certified.