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| Product | Description | |
|---|---|---|
| Maytansine | Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 153858. CAS No. 35846-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13674. |  |
| Maytansine | Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. Synonyms: NSC153858; NSC-153858; NSC 153858; (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-acetyl-N-methyl-L-alaninate. Grade: ≥95%. CAS No. 35846-53-8. Molecular formula: C34H46ClN3O10. Mole weight: 692.2. |  |
| Maytansinoid DM4 | DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N2'-deacetyl-n2'-(4-Mercapto-4-Methyl-1-oxopentyl)-6-MethylMaytansine. Grade: ≥98.0% (HPLC). CAS No. 799840-96-3. Molecular formula: C39H56ClN3O10S. Mole weight: 780.37. | |
| Maytansinoid DM4 | Maytansinoid DM4 is a cytotoxic agent. It is used as a antibody-drug conjugate that has a potential to treat cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 799840-96-3. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C39H56ClN3O10S, Molecular Weight: 794.39. US Biological Life Sciences. |  Worldwide |
| Maytansinol | Maytansinol. Group: Biochemicals. Alternative Names: 3-O-De[2-[methyl(acetyl)amino]-1-oxopropyl]maytansine. Grades: Highly Purified. CAS No. 57103-68-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C28H37ClN2O8. US Biological Life Sciences. | Worldwide |
| Maytansinol | Maytansinol is an ansamacrolide isolated from P. verrucose. It was shown to inhibit microtubule assembly and induces microtubule disassembly in vitro. It exhibits antitumor activity. Synonyms: (3S)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-maytansine; Ansamitocin P-0; NSC239386; NSC-239386; Maytansine; Ansamitocin P 0; Antibiotic C 15003P; NSC 239386. Grade: 95%. CAS No. 57103-68-1. Molecular formula: C28H37ClN2O8. Mole weight: 565.06. | |
| MAZ51 | MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. MAZ51 inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. MAZ51 had no effect on ligand-induced autophosphorylation of EGFR, IGF-1R and PDGFR?. MAZ51 blocks proliferation and induces apoptosis in a wide variety of tumor cells. Antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 163655-37-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116624. | |
| Mazdutide | Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide ( GLP-1R ) and glucagon receptor ( GCGR ). Mazdutide binds human and mouse GCGR ( K i : 17.7 nM and 15.9 nM, respectively) and GLP-1R ( K i : 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets ( EC 50 : 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: IBI-362; LY-3305677; OXM-3. CAS No. 2259884-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3375. | |
| Mazdutide | Mazdutide is a long-acting glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. Mazdutide has been use in the research of type 2 diabetes mellitus (T2DM). Synonyms: IBI362; IBI 362; IBI-362; LY3305677; LY 3305677; LY-3305677; OXM3; OXM-3; OXM 3. CAS No. 2259884-03-0. Molecular formula: C207H317N45O65. Mole weight: 4476. | |
| Mazisotine | SSTR4 agonist-1 (Compound 47) is a selective agonist for somatostatin receptor subtype 4 ( SSTR4 ) with an EC 50 of 4.7 nM. SSTR4 agonist-1 reveals a half-life > 130 minutes in human liver microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638588-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139347. | |
| MB05032 | MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 261365-11-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16307. | |
| MB-3 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| MB710 | MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C , with a K d of 4.1?μM. MB710 shows anticancer activity in p53-Y220C cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230044-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120373. | |
| Mbba | Mbba. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-[(p-methoxybenzylidene)amino]-4-butylbenzene;1-butyl-4-[(p-methoxybenzylidene)amino]benzene;4'-methoxybenzylidiene-4-butylaniline;4-butyl-n-((4-methoxyphenyl)methylene)-benzeneamin;4-butyl-n-[(4-methoxyphenyl)methylene]-benzenamin;4-Butyl-N-[(4-methoxyp. Product Category: Organic & Printed Electronics. CAS No. 26227-73-6. Molecular formula: C18H21NO. Mole weight: 267.37. Purity: >98.0%(GC)(T). Product ID: ACM26227736. Alfa Chemistry ISO 9001:2015 Certified. |  |
| mBBr | mBBr. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Monobromobimane. Product Category: Other Fluorophores. Appearance: Yellow powder. CAS No. 71418-44-5. Molecular formula: C10H11BrN2O2. Mole weight: 271.11. Purity: 95%+. IUPACName: 7-(bromomethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione. Canonical SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C. Density: 1.66 ± 0.1 g/ml. Product ID: ACM71418445-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| mBCl | mBCl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Monochlorobimane. Product Category: Other Fluorophores. CAS No. 76421-73-3. Molecular formula: C10H11ClN2O2. Mole weight: 226.66. Purity: 95%+. IUPACName: 7-(chloromethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione. Canonical SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CCl)C. Product ID: ACM76421733-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: BENOMYL, MB A-Class. | |
| MBCQ | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MBD | MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole. CAS No. 33984-50-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-141667. | |
| MBD-7 | MBD-7 is isolated from Mus musculus (Mouse) and has bactericidal activity. Synonyms: Beta-defensin 7; BD-7; Defensin, beta 7. | |
| m-Benzenedimethanol | Benzenedimethanol. CAS No. 626-18-6. Categories: 1,3-benzenedimethanol. |  Pennsylvania PA |
| m-(Benzyloxy)benzyl Chloride | m-(Benzyloxy)benzyl Chloride. Group: Biochemicals. Alternative Names: 1-Benzyloxy-3-chloromethylbenzene; 3-(Benzyloxy)benzyl Chloride; Benzyl α-Chloro-m-tolyl Ether. Grades: Highly Purified. CAS No. 24033-03-2. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| MBHA Resin | MBHA Resin. | |
| MBMAP28 | BMAP-28 has broad antimicrobial activities and confers protection in an animal model: mouse of bacterial infection or sepsis. | |
| M(Boc) Acetic acid | A nucleobase for PNA synthesis. Synonyms: (6-tert-butoxycarbonylaminopyridin-3-yl) acetic acid. Grade: 98%. CAS No. 1256337-02-6. Molecular formula: C12H16N2O4. Mole weight: 252.27. | |
| Mbo II | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme approximately 60% of the dna fragments can be ligated and recut. in presence of 10%peg ligation is better. Group: Restriction Enzymes. Purity: 200U; 1000U. GAAGA(N)8↑ CTTCT(N)7&darr. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Mbo II from Moraxella bovis. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1130RE. |  |
| MBP (85-106) guinea pig, MBP (86-107) human | MBP (85-106) guinea pig, MBP (86-107) human is a 85-106 fragment of the guinea pig, myelin basic protein (MBP) or 86-107 fragment of the human MBP. It is used in multiple sclerosis research. Synonyms: H-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-Pro-Pro-Ser-Gln-Gly-Lys-Gly-Arg-OH; Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-Pro-Pro-Ser-Gln-Gly-Lys-Gly-Arg. Molecular formula: C113H180N34O28. Mole weight: 2463. | |
| MBP (85-99) peptide antagonist trifluoroacetate salt | 95% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| m-BPDBT | m-BPDBT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,3'-Bis(dibenzo[b,d]thiophen-4-yl)-1,1'-biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1128045-14-6. Molecular formula: C36H22S2. Mole weight: 518.69 g/mol. Product ID: ACM1128045146. Alfa Chemistry ISO 9001:2015 Certified. | |
| m-Bpye | m-Bpye. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Di(pyren-1-yl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1616657-81-8. Molecular formula: C38H22. Mole weight: 478.58 g/mol. Product ID: ACM1616657818. Alfa Chemistry ISO 9001:2015 Certified. Categories: M'Baye Niang. | |
| m-BPySCz | m-BPySCz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3-(9H-Carbazol-9-yl)-phenyl)-3-(pyridine-3-yl)pyridine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2245948-99-4. Molecular formula: C28H19N3. Mole weight: 397.47 g/mol. Product ID: ACM2245948994. Alfa Chemistry ISO 9001:2015 Certified. | |
| MBQ-167 | MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097938-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112842. | |
| m-Bromobenzontitride | m-Bromobenzontitride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-bromoethoxy)-4-t-butylbenzene; p-(2-bromoethoxy)-tert-butylbenzene; 2-bromo-1-(4-tert-butylphenoxy)ethane; 1-[4-(tert-butyl)phenoxy]-2-bromoethane; bromoethylbutylphenylether; <2-Brom-aethyl>-<4-tert.-butyl-phenyl>-aether; 1-(2-bromoethox. Product Category: Heterocyclic Organic Compound. CAS No. 5952-59-6. Molecular formula: C12H17BrO. Mole weight: 257.167. Purity: 0.96. IUPACName: 1-(2-bromoethoxy)-4-tert-butylbenzene. Density: 1.225g/cm³. Product ID: ACM5952596. Alfa Chemistry ISO 9001:2015 Certified. | |
| MBS | MBS. CAS No. 58626-38-3. Pack Sizes: Milligram Quantities: 100 mg. Order Number: CL202. |  www.prochemonline.com |
| MBS | DryPowder; PelletsLargeCrystals. Group: Polymers. Product ID: 4-(1,3-benzothiazol-2-ylsulfanyl)morpholine. Molecular formula: 252.4g/mol. Mole weight: C11H12N2OS2. C1COCCN1SC2=NC3=CC=CC=C3S2. InChI=1S/C11H12N2OS2/c1-2-4-10-9 (3-1)12-11 (15-10)16-13-5-7-14-8-6-13/h1-4H, 5-8H2. MHKLKWCYGIBEQF-UHFFFAOYSA-N. |  |
| MBTH | MBTH. CAS No. 38894-11-0. Categories: 2-hydrazono-3-methyl-2,3-dihydrobenzo[d]thiazole hydrochloride hydrate. | Pennsylvania PA |
| MBX-102 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MBX-102 acid | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| MBX2546 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MBX-2982 | MBX-2982 is a selective, orally-available G protein-coupled receptor 119 ( GPR119 ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037792-44-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15291. | |
| MC-031 | MC-031, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.6×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylchlorothricin. CAS No. 134637-04-0. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-032 | MC-032, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.5×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: O-Demethylhydroxychlorothricin. CAS No. 134615-17-1. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
| MC-033 | MC-033, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 1.06×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: MC 033; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-15-9. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-034 | MC-034, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 18.3×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Synonyms: MC 034; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-2A-hydroxy-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-16-0. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
| MC 1443 | MC 1443. Group: Biochemicals. Alternative Names: 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole. Grades: Highly Purified. CAS No. 163239-22-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H11FN2. US Biological Life Sciences. | Worldwide |
| MC1568 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MC1568 | MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor, used for cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 852475-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16914. | |
| MC 1568 | A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Group: Biochemicals. Alternative Names: 3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide. Grades: Highly Purified. CAS No. 852475-26-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MC2050 hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MC70 | MC70 is a potent and non-selective P-glycoprotein (P-gp) inhibitor with an EC 50 of 0.69 μM. MC70 is an ABC transporters inhibitor and anticancer agent. MC70 interacts with ABCB1, ABCG2 and ABCC1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031367-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113805. | |
| MCA | MCA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Methoxycoumarin-4-acetic acid. Product Category: Other Fluorophores. CAS No. 62935-72-2. Molecular formula: C12H10O5. Mole weight: 234.2. Product ID: ACM62935722. Alfa Chemistry ISO 9001:2015 Certified. | |
| MCA | MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62935-72-2. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W027544. | |
| MC-AAA-NHCH2OCH2COOH | MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414594-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132159. | |
| Mca-(Ala7,Lys(Dnp)9)-Bradykinin | Mca-(Ala7,Lys(Dnp)9)-Bradykinin is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1), a membrane-bound zinc metallopeptidase related to neprilysin in amino acid sequence. It is used as a substrate for insulin-degrading enzymes (IDE) and ACE2. Synonyms: Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH; N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine; (7-methoxycoumarin-4-yl)acetyl-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(2,4-dinitrophenyl); N2-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-alanyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine. Grade: 95%. CAS No. 323577-36-2. Molecular formula: C66H81N15O19. Mole weight: 1388.44. | |
| Mca-Ala-Pro-Lys(Dnp)-OH | Mca-Ala-Pro-Lys(Dnp)-OH, a FRET substrate for angiotensin-converting enzyme 2 (ACE2), is used to monitor enzyme activity in plasma, urine, heart and lungs. Synonyms: Mca-APK(Dnp); L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine; (S)-6-((2,4-dinitrophenyl)amino)-2-((S)-1-((S)-2-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamido)propanoyl)pyrrolidine-2-carboxamido)hexanoic acid. Grade: ≥95%. CAS No. 305336-82-7. Molecular formula: C32H36N6O12. Mole weight: 696.67. | |
| Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide | Mca-Amyloid β/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide, a fluorescent (FRET) peptide substrate containing the wild-type amyloid precursor protein (APP) β-secretase cleavage site, is used to determine the β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). TOP is a potential β-secretase candidate and is involved in APP processing in vivo. Synonyms: Mca-APP770 (667-676)-Lys(Dnp)-Arg-Arg amide; Mca-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2; Mca-SEVKMDAEFRK(Dnp)RR-amide. Grade: ≥95% by HPLC. CAS No. 1802078-33-6. Molecular formula: C87H129N27O28S. Mole weight: 2033.21. | |
| Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 | Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2, the FRET substrate, is hydrolyzed 60 times more rapidly by stromelysin 1 (MMP-3) (kcat/Km= 59400 M-1s-1) than by interstitial collagenase (MMP-1). However, it shows little discrimination between MMP-3, gelatinase A (MMP-2) (kcat/Km= 54000 M-1s-1), and gelatinase B (MMP-9) (kcat/Km = 55300 M-1s-1). This fluorogenic substrate is digested by Metalloelastase (MMP-12) with a kcat/Km of 243000 M-1s-1. Synonyms: NFF-2; 7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-(2,4-dinitrophenyl)Lys amide; N2-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-tyrosyl-L-alanyl-L-norvalyl-L-tryptophyl-L-methionyl-N6-(2,4-dinitrophenyl)-L-lysinamide. Grade: ≥95%. CAS No. 158584-08-8. Molecular formula: C79H105N19O19S. Mole weight: 1656.86. | |
| Mca-[Asn670, Leu671]-Amyloid ?/A4 Precursor Protein 770 fragment 667-675-(Dnp)Lys amide | ?96% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) | Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) is a pro-memapsin-2 fluorogenic substrate (FRET) containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF. Synonyms: Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp); Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine; L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-. Grade: ≥95%. CAS No. 1802078-31-4. Molecular formula: C68H88N14O27. Mole weight: 1533.53. | |
| Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide | Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide is a fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP. Its kinetic parameters at pH 4.5 are Km = 4.5 μM and kcat = 0.25 min-1. Synonyms: Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp) amide; Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-NH2; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysinamide; L-Lysinamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-; Mca-SEVNLDAEFK(Dnp) amide. Grade: ≥95%. CAS No. 1802078-32-5. Molecular formula: C68H89N15O26. Mole weight: 1532.54. | |
| Mca-(endo-1a-dap(dnp))-tnf-alpha(-5 to +6)amide(human) | Mca-(endo-1a-dap(dnp))-tnf-alpha(-5 to +6)amide(human). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ADAM-17 SUBSTRATE II, FLUOROGENIC;MCA-(ENDO-1A-DAP(DNP))-TNF-A (-5 TO +6) AMIDE (HUMAN);MCA-(ENDO-1A-DAP(DNP))-TNF-ALPHA (-5 TO +6) AMIDE (HUMAN);MCA-(ENDO-1A-DAP(DNP))-TUMOR NECROSIS FACTOR-ALPHA (-5 TO +6) AMIDE (HUMAN);MCA-PRO-LEU-ALA-GLN-ALA-VAL-DAP(. Product Category: Heterocyclic Organic Compound. CAS No. 192723-42-5. Molecular formula: C69H103N23O24. Mole weight: 1638.7. Product ID: ACM192723425. Alfa Chemistry ISO 9001:2015 Certified. | |
| Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (human) | Mca-(endo-1a-Dap(Dnp))-TNF-α (-5 to +6) amide (human), a fluorogenic (FRET) peptide substrate, is used for the tumor necrosis factor (TNF) converting enzyme (TACE, ADAM-17 endopeptidase). Synonyms: Mca-(endo-1a-Dap(Dnp))-TNF-a (-5 to +6) amide (human); Mca-Pro-Leu-Ala-Gln-Ala-Val-Dap(Dnp)-Arg-Ser-Ser-Ser-Arg-NH2; L-Argininamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-; 1-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-L-argininamide. Grade: ≥95% by HPLC. CAS No. 192723-42-5. Molecular formula: C69H103N23O24. Mole weight: 1638.72. | |
| Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2 | Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2, a FRET substrate for cathepsin D and E, is also cleaved by napsin A. Synonyms: MOCAc-GKPILFFRL-{Lys(Dnp)}-{D-Arg}-NH2; Mca-GKPILFFRL-Dpa-r-amide; MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-{Lys(Dnp)}-{D-Arg}-NH2; N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-(2,4-dinitrophenyl)-L-lysyl-D-argininamide; D-Argininamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N6-(2,4-dinitrophenyl)-L-lysyl-; Cathepsin D and E FRET Substrate. Grade: ≥90%. CAS No. 839730-93-7. Molecular formula: C85H122N22O19. Mole weight: 1756.01. | |
| MCA-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys(DNP)-NH2 trifluoroacetate salt | ?95% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| MCA-Lys-Leu-Lys(Dnp) | MCA-Lys-Leu-Lys(Dnp). Synonyms: N6-(2,4-dinitrophenyl)-N2-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysyl-L-leucyl-L-lysine. Molecular formula: C36H47N7O12. Mole weight: 769.81. | |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-KPLGL-Dpa-AR-NH2 is an N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH2 with a Lys yields a fluorogenic peptide with improved substrate properties. Compared with Mca-PLGL-Dpa-AR-NH2, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH2 for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased by 2-9 times and 3 times, respectively, while those for gelatinases and matrilysin remain equally high. Synonyms: L-Argininamide, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-; N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-L-argininamide; MMPs substrate Fluorogenic. Grade: ≥95%. CAS No. 720710-69-0. Molecular formula: C55H80N16O16. Mole weight: 1221.32. | |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1[1]. (Ex/Em=325 nm/400 nm). Uses: Scientific research. Group: Peptides. Alternative Names: Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. CAS No. 720710-69-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4931. | |
| Mca-PL | Mca-PL is a fluorogenic peptide that can be used in the synthesis of Mca-PLGL-Dpa-AR-NH2, a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-7 Fluorogenic Substrate Control; Mca-Pro-Leu-OH; MMP-2/MMP-7 Fluorogenic Substrate Control; N-[1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl]-L-leucine. Grade: ≥95%. CAS No. 140430-55-3. Molecular formula: C23H28N2O7. Mole weight: 444.48. | |
| Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is a highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85·105 M-1s-1. It is a poor substrate of other MMPs with the exception of MMP-13 (kcat/Km = 0.53·105 M-1s-1) and MMP-9 (kcat/Km = 0.33·105 M-1s-1). Synonyms: L-Alaninamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-; 1-[(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-L-alaninamide. Grade: 95%. CAS No. 891198-38-2. Molecular formula: C53H70N12O20. Mole weight: 1195.19. | |
| Mca-pro-leu-gly-pro-D-lys(dnp)-oh | Mca-pro-leu-gly-pro-D-lys(dnp)-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MCA-PRO-LEU-GLY-PRO-DLYS(DNP);MCA-PRO-LEU-GLY-PRO-D-LYS(DNP)-OH. Product Category: Heterocyclic Organic Compound. CAS No. 185698-23-1. Molecular formula: C42H52N8O14. Mole weight: 892.91. Product ID: ACM185698231. Alfa Chemistry ISO 9001:2015 Certified. | |
| m-Carborane | m-Carborane. Group: Electronic materials. Alternative Names: 1,7-DICARBADODECARBORANE(12); M-CARBORANE; 1,7-Dicarba-closo-dodecaboran; 1,7-Dicarba-closo-dodecaborane(12); 1,7-Dicarbadodecaboran; 1,7-Dicarbadodecaboran(12); 1,7-Dicarbadodecaborane; 1,7-dicarbadodecaborane(12). CAS No. 16986-24-6. Molecular formula: 134.2g/mol. Mole weight: C2H2B10. [B]1[B][B][B][B]C2[B]C ([B]2)[B][B][B]1. InChI=1S/C2H2B10/c3-1-4-2 (3)6-8-10-12-11-9-7-5-1/h1-2H. JTWJUVSLJRLZFF-UHFFFAOYSA-N. | |
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