A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Nizatidine EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 188666-11-7. Molecular Formula: C11H18N4O3S2. Mole Weight: 318.41. Catalog: APB188666117.
Nizatidine EP Impurity F
An impurity of Nizatidine, which is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM. Synonyms: N1,N1'-[2,4-Thiazolediylbis(methylenethio-2,1-ethanediyl)]bis(N'-methyl-2-nitro-1,1-ethenediamine). Grades: > 95%. CAS No. 1193434-62-6. Molecular formula: C15H25N7O4S3. Mole weight: 463.6.
Nizatidine EP Impurity H
Nizatidine EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 27366-72-9. Molecular Formula: C4H11ClN2S. Mole Weight: 154.66. Catalog: APB27366729.
Nizatidine EP Impurity I
Nizatidine EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82586-81-0. Molecular Formula: C11H20N4OS2. Mole Weight: 288.43. Catalog: APB82586810.
Nizatidine EP Impurity J
Nizatidine EP Impurity J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 78441-69-7. Molecular Formula: C7H12N2OS. Mole Weight: 172.25. Catalog: APB78441697.
Nizatidine impurity 1
Nizatidine impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 92759-37-0. Molecular Formula: C7H13ClN2OS. Mole Weight: 208.7. Catalog: APB92759370.
Nizatidine Impurity A
An impurity of Nizatidine, which is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM. Synonyms: N,N'-Dimethyl-2-nitro-1,1-ethenediamine; 1,1-Bis(methylamino)-2-nitroethene; Nizatidine EP Impurity A. Grades: > 95%. CAS No. 54252-45-8. Molecular formula: C4H9N3O2. Mole weight: 131.14.
Histamine H2-receptor antagonist related to ranitidine. Group: Biochemicals. Alternative Names: N- [2- [ [ [2- [ (Dimethylamino) methyl] -4-thiazolyl] methyl] thio] ethyl] -N-methyl-2-nitro-1, 1-ethenediamine; LY-139037; ZE-101; ZL-101; Axid; Calmaxid; Cronizat; Distaxid; Gastrax; Nizax; Nizaxid. Grades: Highly Purified. CAS No. 76963-41-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Nizatidine Sulfoxide
Nizatidine Sulfoxide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Nizatidine Imp. C (EP),(EZ)-N-[2-[[[2-[(Dimethylamino)methyl]thiazol-4-yl]methyl]sulphinyl]ethyl]-N'-methyl-2-nitroethene-1,1-diamine. CAS No. 102273-13-2. Pack Sizes: 10MG. IUPAC Name: 1-N'-[2-[[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methylsulfinyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine. Molecular Formula: C12H21N5O3S2. Mole Weight: 347.46. Catalog: APS102273132A. SMILES: CNC(=C[N+](=O)[O-])NCCS(=O)Cc1csc(CN(C)C)n1. Format: Neat. Shipping: Room Temperature.
Nizofenone fumarate
Nizofenone fumarate. Group: Biochemicals. Grades: Highly Purified. CAS No. 54533-86-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
N-[(+)-Jasmonoyl]-(L)-isoleucine
N-[(+)-Jasmonoyl]-(L)-isoleucine has been used in synthetic preparation of isoleucine conjugate of epi-jasmonic acid. Synonyms: JA-L-Ile; N-[(1S,2S)-3-oxo-2-(2-(Z)-pentenyl)cyclopentane-1-acetyl]-isoleucine. CAS No. 120330-92-9. Molecular formula: C18H29NO4. Mole weight: 323.43.
NK 1001
NK 1001 is produced by the strain of Streptomyces kanamyceticus var. NK 1001 has weak activity against gram-positive, gram-negative and mycobacterium bacteria. Synonyms: Antibiotic NK 1001; 4,6-Diamino-3-(hexopyranosyloxy)-2-hydroxycyclohexyl 6-amino-6-deoxyhexopyranoside. CAS No. 53025-93-7. Molecular formula: C18H35N3O12. Mole weight: 485.48.
NK-1013-1
NK-1013-1 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive bacteria. Synonyms: Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-N(sup 3)-acetyl-, D-. CAS No. 102612-61-3. Molecular formula: C20H38N4O13. Mole weight: 542.5.
NK-1013-2
NK-1013-2 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive and gram-negative bacteria. Molecular formula: C22H40N4O14. Mole weight: 584.6.
NK10958P
NK10958P is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: NK-10958P. Molecular formula: C18H30O4. Mole weight: 310.4.
NK-1145 Hydrochloride
The hydrochloride salt form of NK-1145, an azabicyclo derivative, has been found to be a parasympatholytic drug that could induce stimulation and excitement. Synonyms: NK-1145 hydrocholdoride; NK1145; NK 1145; NK-1145; Phenyl tropan-3alpha-yl ester; NK 1145; Tropine-3-beta-phenyl ether hydrochloride; 8-methyl-3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride(1:1). Grades: 98%. CAS No. 16487-37-9. Molecular formula: C14H20ClNO. Mole weight: 253.77.
NK-122
NK-122 is a potential bioactive agent. Uses: A potential bioactive agent. Synonyms: NK122; NK 122; NK-122; 1-(1H-indol-2-yl)-2-methylpropan-2-amine hydrochloride. Grades: ≥98%. CAS No. 3417-71-8. Molecular formula: C12H17ClN2. Mole weight: 224.73.
NK 154183A
NK 154183A is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183A; (4E, 18E)-11, 12, 13, 14, 16, 17, 27a-Heptahydroxy-6'-(2-hydroxybutyl)-2, 2, 11, 15, 17, 28-hexamethyl-2, 3, 3', 3a, 4', 5', 6, 6', 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 26, 27, 27a-tetracosahydro-20H-spiro[22, 26-methanofuro[2, 3-h][1, 5]dioxacyclohexacosine-24, 2'-pyran]-20-one. CAS No. 152986-47-5. Molecular formula: C41H70O13. Mole weight: 771.
NK 154183B
NK 154183B is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183B; (4E, 18E)-13-{[5-(Dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-11, 12, 14, 16, 17, 27a-hexahydroxy-6'-(2-hydroxybutyl)-2, 2, 11, 15, 17, 28-hexamethyl-2, 3, 3', 3a, 4', 5', 6, 6', 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 26, 27, 27a-tetracosahydro-20H-spiro[22, 26-methanofuro[2, 3-h][1, 5]dioxacyclohexacosine-24, 2'-pyran]-20-one. CAS No. 152986-49-7. Molecular formula: C49H85NO14. Mole weight: 912.2.
NK1 receptor antagonist 2
NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 579475-17-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145250.
NK 252
NK 252. Group: Biochemicals. Grades: Purified. CAS No. 1414963-82-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NK 252
NK 252 is a Nrf2 activator. It can induce expression of an antioxidant response element promoter driven reporter gene. Synonyms: NK-252; NK 252; NK252; N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea. Grades: ≥98% by HPLC. CAS No. 1414963-82-8. Molecular formula: C13H11N5O3. Mole weight: 285.26.
NK-252
NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2 -activating potential. Uses: Scientific research. Group: Signaling pathways. CAS No. 1414963-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19734.
NK30424A
NK30424A is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 1 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8.
NK30424B
NK30424B is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 0.9 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8.
NK314
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduced both cleavable complex-mediated DNA breaks and proteinase K-independent DNA breaks, but protease inhibitors and nuclease inhibitors only decreased the latter. These results indicate that NK314 might affect topoisomerase II in the different manner from cleavable complex formation and activate intracellular proteinase and nuclease to produce DNA fragmentation. As a result of this unique mechanism of DNA breakage, NK314 showed substantial growth inhibition of topoisomerase II inhibitor-resistant tumors. Synonyms: NK-314; NK 314. Grades: 98%. CAS No. 208237-49-4. Molecular formula: C22H18ClNO4. Mole weight: 395.84.
NK374200
NK374200 is an insecticidal agent produced by Taralomyces. Molecular formula: C12H17N7O3. Mole weight: 307.31.
An autoinducer of P. fischeri luciferase. A specfic genetic regulator that is unrelated to at least one of the enzyme systems that it induces, and it acts after excretion and accumulation in the extracellular medium. Group: Biochemicals. Alternative Names: N-(3-Oxohexanoyl)-homoserine Lactone. Grades: Highly Purified. CAS No. 143537-62-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
NKH 477
NKH 477 is a water-soluble analog of Forskolin, that is a potent activator of adenylyl cyclase, which shows some selectivity for cardiac (type V) adenylyl cyclase). Group: Biochemicals. Alternative Names: N,N-Dimethyl- β-alanine (3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-10, 10b-dihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-6-yl Ester HCl; N,N-Dimethyl- β-alanine [3R-(3α,4a β,5 β,6 β, 6aα, 10α, 10a β,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester HCl; 1H-Naphtho[2,1-b]pyran, β-alanine deriv.; 6- (3-Di methyl aminopropionyl) forskolin HCl; Adehl; Colforsin Dapropate HCl. Grades: Highly Purified. CAS No. 138605-00-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??ClNO?, Molecular Weight: 546.09. US Biological Life Sciences.
Worldwide
NKH 477
NKH477 is a water-soluble analog of forskolin, which is an adenylyl cyclase activator, but it is sparingly soluble in aqueous solutions. It has both inotropic and vasodilator effects. Uses: Vasodilator agents. Synonyms: NKH 477; NKH477; NKH-477; N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride. Grades: ≥98% by HPLC. CAS No. 138605-00-2. Molecular formula: C27H43NO8.HCl. Mole weight: 546.1.
NKL-22
NKL-22 is a HDAC inhibitor with IC 50 value of 78 uM. It is a cell-permeable pimeloylanilide compound which acts as a FXN-(frataxin gene) specific HDAC inhibitor. It increase frataxin protein concentrations. It increase FXN mRNA in FRDA lymphocytes. Uses: Nkl-22 it increase fxn mrna in frda lymphocytes. Synonyms: HDAC inhibitor IV; NKL 22; NKL-22; NKL22; MDK-4154; MDK4154; MDK4154; N-(2-Aminophenyl)-N'-phenylheptanediamide;HDAC inhibitor IV;N1-(2-Aminophenyl)-N7-phenylheptanediamide;Histone Deacetylase Inhibitor IV. Grades: 98%. CAS No. 537034-15-4. Molecular formula: C19H23N3O2. Mole weight: 325.40.
NKY 80
NKY 80. Group: Biochemicals. Grades: Purified. CAS No. 299442-43-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NKY 80
NKY80 is a selective inhibitor of adenylyl cyclase 5 with IC50 value of 8.3 μM. Synonyms: NKY80; NKY 80; NKY-80. 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone. Grades: ≥98% by HPLC. CAS No. 299442-43-6. Molecular formula: C12H11N3O2. Mole weight: 229.23.
NL-103
NL-103, a nicotinamide derivative, has been found to be an inhibitor of both histone deacetylases and hedgehog pathway. It was found to exhibit activity in decreasing the expression of Gli2 so that could probably be significant in the biological studies of Hh pathway. Synonyms: NL-103; NL 103; NL103; N-(4-chloro-3-(3-chlorobenzamido)phenyl)-6-((7-(hydroxyamino)-7-oxoheptyl)amino)nicotinamide. Grades: 98%. CAS No. 1788896-33-2. Molecular formula: C71H108N18O14. Mole weight: 1437.76.
N-Lactoyl-Phenylalanine
N-Lactoyl-Phenylalanine is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-Phenylalanine can reduce obesity and improve glucose tolerance [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lac-Phe. CAS No. 183241-73-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-150012.
N-Lactylleucine
N-Lactylleucine is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 112757-17-2. Pack Sizes: 5 mg. Product ID: HY-164805.
N-Lactylvaline
N-Lactylvaline is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 70190-98-6. Pack Sizes: 5 mg. Product ID: HY-164804.
N-Lauroyl-D-arginine
Heterocyclic Organic Compound. CAS No. 1225433-34-0. Purity: 0.96. Catalog: ACM1225433340.
N-Lauroyl-L-alanine
N-Lauroyl-L-alanine is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 52558-74-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W009379.
N-Lauroyl-l-aspartic acid*
Heterocyclic Organic Compound. CAS No. 1116-13-8. Catalog: ACM1116138.
N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research [1]. Uses: Scientific research. Group: Peptides. CAS No. 97-78-9. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W141881.
N-LAUROYLSARCOSINE
N-LAUROYLSARCOSINE. Synonyms: n-methyl-n-(1-oxododecyl)-glycin;N-methyl-N-(1-oxododecyl)-Glycine;N-LAUROYLSARCOSINE FREE ACID;N-acyl sarcosinate;Glycine, N-methyl-N-(1-oxododecyl)-;n-lauroylsarcosine,neat;N-Lauroylsarkosin;N-Dodecanoyl-N-methylglycine, Sarkosyl L. CAS No. 97-78-9. Pack Sizes: 1 kg. Product ID: CDF4-0094. Molecular formula: C15H29NO3. Category: Food Emulsifiers. Product Keywords: Food Ingredients; Food Emulsifiers; N-LAUROYLSARCOSINE; CDF4-0094; 97-78-9; C15H29NO3; 202-608-3; 97-78-9. Purity: 0.99. Color: White or Colorless to Almost White or Almost colorless. EC Number: 202-608-3. Physical State: Powder to lump to Clear Liquid. Solubility: almost transparency in Methanol. Application: N-Lauroylsarcosine may be used as a permeation enhancer in the transdermal drug delivery formulations since it increases the fluidity of stratum corneum lipid structure of the skin. Boiling Point: 413.2±28.0 °C(Predicted). Melting Point: 45-49 °C. Product Description: N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations,?especially against sexually transmitted diseases (STDs).
N-Lauroylsarcosine sodium salt
500g Pack Size. Group: Amino Acids, Biochemicals. Formula: C15H28NNaO3. CAS No. 137-16-6. Prepack ID 12615111-500g. Molecular Weight 293.38. See USA prepack pricing.
N-Laurylbiotinamide
Heterocyclic Organic Compound. CAS No. 128631-44-7. Catalog: ACM128631447.
NLCQ-1
NLCQ-1 is a novel weakly DNA-intercalative bioreductive compound. NLCQ-1 exhibited a C50 of 44 microM. NLCQ-1 demonstrated significant hypoxic selectivity in several rodent (V79, EMT6, SCCVII) or human (A549, OVCAR-3) tumor cell lines. Its potency as a hypoxic cytotoxin ranged between 10 and 136 microM x h, for the cell lines tested, at 30 microM input concentration. NLCQ-1 was a very potent and efficient radiosensitizer of hypoxic V79 cells, providing SER values of 2.27-2.56 at 20-80 microM concentration (measured at 10% survival level). Preclinical results suggest a possible use of NLCQ-1 as adjuvants to radiotherapy. Synonyms: NLCQ 1; NLCQ1; NSC 709257; NSC-709257; NSC709257; 4-(3-(2-nitro-1-imidazolyl)-propylamino)-7-chloroquinoline hydrochloride. CAS No. 221292-08-6. Molecular formula: C15H15Cl2N5O2. Mole weight: 368.22.
NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a cytosolic enzyme responsible for the oxidation of the essential amino acid tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, this agent increases tryptophan levels, restores the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, T-lymphocytes, and causes a reduction in tumor-associated regulatory T-cells (Tregs). Synonyms: GDC0919; GDC-0919; GDC 0919; NLG919; NLG 919; NLG-919; RG6078; RG-6078; RG 6078. Grades: > 98%. CAS No. 1402836-58-1. Molecular formula: C18H22N2O. Mole weight: 282.38.
N-L-γ-glutamyl-L-tyrosine
N-L-γ-glutamyl-L-tyrosine is a dipeptide produced by the catabolism of proteins. Synonyms: Gamma-Glutamyltyrosine; H-gamma-Glu-Tyr-OH; H-Glu(Tyr-OH)-OH. Grades: ≥95%. CAS No. 7432-23-7. Molecular formula: C14H18N2O6. Mole weight: 310.31.
N-lignoceroyl-D-erythro-sphingosine
N-lignoceroyl-D-erythro-sphingosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 102917-80-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C42H83NO3. US Biological Life Sciences.
Worldwide
N-Linked Timolol Impurity HCl
An impurity of Ticlopidine which is a non-cardioselective beta-blocker and it has no intrinsic sympathomimetic or membrane stabilizing effect. Grades: > 95%. Molecular formula: C13H24N4O3S.HCl. Mole weight: 352.89.
Does not act on N-acylsphingosine or N,O-diacylethanolamine. Group: Enzymes. Synonyms: N-acylethanolamine amidohydrolase; acylethanolamine amidase. Enzyme Commission Number: EC 3.5.1.60. CAS No. 99283-61-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4450; N-(long-chain-acyl)ethanolamine deacylase; EC 3.5.1.60; 99283-61-1; N-acylethanolamine amidohydrolase; acylethanolamine amidase. Cat No: EXWM-4450.
N-Losartanyl-losartan
N-Losartanyl-losartan
Sarchem Laboratories New Jersey NJ
NLP-28
NLP-28 is an antimicrobial peptide found in Caenorhabditis elegans, and has antifungal activity. Synonyms: Neuropeptide-like protein 28. Grades: >85%.
NLP-31
NLP-31 is an antimicrobial peptide found in Caenorhabditis elegans, and has antifungal activity against D.coniospora. It has weak antibacterial activity against gram-positive bacteria M.luteus and gram-negative E.coli. Synonyms: Neuropeptide-like protein 31. Grades: >85%.
N-(L-Prolyl)- β-alanine
N-(L-Prolyl)- β-alanine is a derivative of β-Alanine (A637320); a naturally occurring beta amino acid that is formed in vivo by the degradation of Dihydro Uracil (D449990) and Carnosine (C184190). β-Alanine is also the rate-limiting precursor of Carnosine, as a result supplementation with β-alanine increases the concentration of Carnosine in muscles. Group: Biochemicals. Grades: Highly Purified. CAS No. 112558-45-9. Pack Sizes: 100mg, 1g. Molecular Formula: C8H14N2O3, Molecular Weight: 186.21. US Biological Life Sciences.
Worldwide
N-L-Prolyl-L-histidine
Prolyl-histidine is a dipeptide composed of proline and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-Pro-His-OH; H-PH-OH; L-prolyl-L-histidine; Prolyl-Histidine; L-Histidine, L-prolyl-; (S)-3-(1H-Imidazol-4-yl)-2-((S)-pyrrolidine-2-carboxamido)propanoic acid; N-prolyl histidine. Grades: ≥95%. CAS No. 92027-43-5. Molecular formula: C11H16N4O3. Mole weight: 252.27.
NLRP3-IN-11
NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC 50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2769040-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148187.
NLRP3-IN-18
NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC 50 value of ≤1.0 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2769040-06-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153554.
NLRP3-IN-2
NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16673-34-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W011082.
NLRP3-IN-25
NLRP3-IN-25 (compound 32) is an orally available NLRP3 inhibitor with anti-inflammatory activity. NLRP3-IN-25 attenuates renal injury in doxorubicin-induced glomerulonephritis in mice. NLRP3-IN-25 inhibits IL-1β secretion in THP-1 cells with an IC 50 of 21 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2660230-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155463.
NLRP3-IN-9
NLRP3-IN-9 is an inhibitor of caspase-1 and NLRP3 ATPase activities. It acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner. Group: Inhibitors. Alternative Names: NLRP3-IN-9; NLRP3 IN 9; NLRP3IN9; INF-4E; INF 4E; INF4E. CAS No. 88039-46-7. Molecular formula: C12H13ClO3. Mole weight: 240.68. Appearance: Solid powder. Purity: >98%. IUPACName: Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate. Canonical SMILES: C=C(C(C1=CC=CC=C1Cl)O)C(OCC)=O. Catalog: ACM88039467.