A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Echinacea Angustifolia Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Echinacea Purpurea Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Eleuthero Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Forskohlii Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Garcinia Hydroxycitrate Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered ginger
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Holy Basil Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered kava extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Malabar-Nut-Tree, Leaf Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered milk thistle extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Phyllanthus Amarus Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Red Clover Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Rosemary Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Rosemary Hydrophilic Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered St. John?s Wort Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Powdered Valerian Extract
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
p-Oxalotoluidide
p-Oxalotoluidide. Group: Biochemicals. Alternative Names: N1, N2-Bis (4-methylphenyl) ethanediamide; N, N'-Bis (4-methylphenyl) ethanediamide; NSC 401961. Grades: Highly Purified. CAS No. 3299-61-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C16H16N2O2. US Biological Life Sciences.
Worldwide
p-Oxanisidide
p-Oxanisidide. Group: Biochemicals. Alternative Names: N1, N2-Bis (4-methoxyphenyl) ethanediamide; N,N'-Bis(4-methoxyphenyl)oxamide; N,N'-Di-p-anisylamide. Grades: Highly Purified. CAS No. 3299-63-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C16H16N2O4. US Biological Life Sciences.
Worldwide
Pozanicline dihydrochloride
Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor ( nAChR ) agonist with a K i of 16.7 nM for binding to [ 3 H]cytisine sites [1]. Pozanicline is an α4β2 -selective nAChR agonist, which binds to rat brain α4β2 nAChR with a K i of 17 nM while binding to α7 nAChR is insignificant [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-089 dihydrochloride. CAS No. 161416-61-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110160.
Pozelimab
Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3918. CAS No. 2096328-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99786.
Poziotinib
Poziotinib (HM781-36B) is an orally active, irreversible pan- HER inhibitor, which effectively inhibits EGFR wt , HER-2 and HER-4 with IC 50 s of 3.2, 5.3 and 23.5 nM, respectively. Poziotinib (HM781-36B) also shows excellent inhibitory activities against mutated EGFRs, including EGFR T790M and EGFR L858R/T790M , with IC 50 s of 4.2 and 2.2 nM, respectively. Excellent antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM781-36B; NOV120101. CAS No. 1092364-38-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15730.
PP1 is a potent, and Src family-selective tyrosine kinase inhibitor with IC 50 of 5 and 6 nM for Lck and Fyn, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGL 1872; EI 275. CAS No. 172889-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13804.
PP 1
PP 1. Group: Biochemicals. Grades: Purified. CAS No. 172889-26-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PP102
PP102 is an antimicrobial peptide found in Pteromalus puparum (endoparasitic wasp), and has antibacterial activity against both gram-negative and gram-positive bacteria, but no activity against fungi. Grade: ≥95%.
PP113
PP113 is an antimicrobial peptide found in Pteromalus puparum (endoparasitic wasp), and has antibacterial activity against both gram-negative and gram-positive bacteria, but no activity against fungi. Grade: >98%.
PP121 is a multi-targeted kinase inhibitor with IC50s of 10, 60, 12, 14, 2 nM for mTOR, DNK-PK, VEGFR2, Src, PDGFR, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092788-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10372.
PP 121
PP 121. Group: Biochemicals. Grades: Purified. CAS No. 1092788-83-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
P, P'-[ (1, 2-Phenylene) bis (methylene) ]bisphosphonic Acid P,P,P',P'-tetraethyl ester
P, P'-[ (1, 2-Phenylene) bis (methylene) ]bisphosphonic Acid P,P,P',P'-tetraethyl ester. Group: Biochemicals. Alternative Names: (o-Phenylenedimethylene) diphosphonic Acid Tetraethyl Ester; [1, 2-Phenylenebis (methylene) ]bisphosphonic Acid Tetraethyl Ester; Tetraethyl o-Xylylenediphosphonate. Grades: Highly Purified. CAS No. 42092-05-7. Pack Sizes: 1g. Molecular Formula: C16H28O6P2, Molecular Weight: 378.34. US Biological Life Sciences.
Worldwide
PP13
PP13 is an antimicrobial peptide found in Pteromalus puparum (endoparasitic wasp). It has antibacterial activity against E. coli, B. subtilis, S. aureus, S. lutea and B. pumilu (MIC 8-23 μM), but no activity against fungi. Synonyms: Gly-Ala-Ala-Arg-Lys-Ser-Ile-Arg-Leu-His-Arg-Leu-Tyr-Thr-Trp-Lys-Ala-Thr-Ile-Tyr-Thr-Arg. Grade: ≥97%. Molecular formula: C121H197N39O29. Mole weight: 2662.15.
Highly potent and selective Scr family tyrosine kinase inhibitor. Shows anti-Ras cancer potential by blocking Ras-induced activation of PAK1. Antitumor compound. RIP2 inhibitor. Blocks TGF-beta-mediated cellular responses. Group: Biochemicals. Alternative Names: 4-Amino-5-(methylphenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine. Grades: Highly Purified. CAS No. 172889-26-8. Pack Sizes: 1mg. US Biological Life Sciences.
PP1 Analog II, CAS 221244-14-0, is a cell-permeable PP1 analog that acts as a potent, reversible, selective, ATP-competitive inhibitor of mutant over wild-type kinases. Group: Fluorescence/luminescence spectroscopy.
PP1 Analog III, 3-MB-PP1 - CAS 956025-83-5
PP1 Analog III, 3-MB-PP1 primarily used in Inhibition. Group: Fluorescence/luminescence spectroscopy.
PP1 Analog IV, 3-IB-PP1 (3-Iodobenzyl PP1 Analog)
A cell-permeable enlarged PP1 analog that acts as a potent, ATP-competitive and reversible inhibitor of asAkt1/2/3 (IC50=28, 240 and 120nM, respectively) over wtAkt1/2/3 (IC50= >10uM). Shown to hyperphosphorylate Akt-Ser473 and -Thr308 in HEK293 cells coexpressed with myr-HA-asAkt1 or myr-HA-asAkt1/2/3 with no effect on pGSK-3bSer9 levels and wtAkt expressing cells. Also, specifically blocks the inhibitory function of membrane asCsk with diminished activity towards wtCsk, induces phosphorylation of Lck-Tyr394 and ERK1/2 in primary mouse T cells (EC50 ~0.5uM) and rapidly activates T cell receptor signaling. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C16H18IN5, Molecular Weight: 407.3. US Biological Life Sciences.
Worldwide
PP1 Analog V, 2,3-DMB-PP1 (4-Amino-1-tert-butyl-3- (2, 3-dimethylbenzyl) pyrazolo[3, 4-d]pyrimidine, 1-tert-Butyl-3-(2,3-dimethylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Syk ASKA Inhibitor II, PDK1 ASKA Inhibitor)
A cell-permeable 3-MB-PP1 analog that is more effective than 3-MB-PP1 in inhibiting SykM442A S505A ASKA- (analog-sensitive kinase alleles) mediated cellular calcium flux (98% vs. 20% inhibition, respectively, by 1uM 2,3-DMB-PP1 or 3-MB-PP1) in Syk MASA-expressing DT40 cells. Also shown to selectively inhibit L159G ASKA, but not wt, PDK1-dependent GSK3&alpha Ser21 and S6 Ser235/236 phosphorylation upon IGF1 stimulation in mES cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 956026-24-7. Pack Sizes: 10mg. US Biological Life Sciences.
PP2 is a reversible and ATP-competitive Src family kinases inhibitor with IC 50 s of 4 and 5 nM for Lck and Fyn , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGL 1879. CAS No. 172889-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13805.
PP2
PP2, also known as AG 1879, is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 μM) and JAK2 (50 μM). Despite its extensive use as a Src-selective inhibitor, recent research has shown that PP2 is non-selective and inhibits many other kinases with similar affinities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PP2; PP-2; PP 2; AG 1879; AG-1879; AG1879. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 172889-27-9. Molecular formula: C15H16ClN5. Mole weight: 301.77. Purity: >98%. IUPACName: 1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Canonical SMILES: NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(Cl)C=C3)=NC=N1. Product ID: ACM172889279. Alfa Chemistry ISO 9001:2015 Certified.
PP 2
PP 2. Group: Biochemicals. Alternative Names: AGL 1879; PP 2 (enzyme inhibitor); Src kinase inhibitor PP2; 3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Grades: Highly Purified. CAS No. 172889-27-9. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C15H16ClN5, Molecular Weight: 301.77. US Biological Life Sciences.
Worldwide
PP 242
PP 242. Group: Biochemicals. Alternative Names: 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol. Grades: Highly Purified. CAS No. 1092351-67-1. Pack Sizes: 10mg. Molecular Formula: C16H16N6O, Molecular Weight: 308.339999999999. US Biological Life Sciences.
A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC?? = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092351-67-1. Pack Sizes: 1mg. US Biological Life Sciences.
PP2 (4-Amino-5-(4-chlorophenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine, AG 1879)
Highly potent and selective Scr family tyrosine kinase inhibitor. Reduces cancer metastasis. Apoptotic. Antitumor compound. RIP2 inhbitor. Blocks TGF-beta-mediated cellular responses. Autophagy modulator. Group: Biochemicals. Alternative Names: 4-Amino-5-(4-chlorophenyl)-7-(tert.butyl)pyrazolo-(3,4-d)pyrimidine. Grades: Highly Purified. CAS No. 172889-27-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H16ClN5, Molecular Weight: 301.8. US Biological Life Sciences.
Worldwide
PP2A Activating Ligand, ITH12246
A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A). Exhibits blood-brain barrier permeability. Protects neurons against beta-amyloid peptides (Ab1-42) toxicity and okadaic acid-induced tau hyperphosphorylation. Also protects against rotenone and oligomycin A induced neurotoxicity in SH-SY5Y neuroblastoma cells (at ~300nM). Prevents the development of glutamate-induced neuronal lesions in rat hippocampal slices by up-regulating PP2A (~3uM). Shown to reverse the scopolamine-induced memory loss in mice (~10mg/kg i.p) and significantly reduces the infarct volume in an animal model of stroke (~2.5mg/kg). Also acts as an inhibitor of acetylcholinesterase activity in Electrophorus electricus (IC50 = 60nM) and human erythrocytes (IC50 = 780nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences.
PP2, CAS 172889-27-9, is a potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases (IC?? = 4, 5, 5, &100 nM for p56lck, p59fynT, Hck, & Src, respectively). Group: Fluorescence/luminescence spectroscopy.
PP 3
PP 3. Group: Biochemicals. Grades: Purified. CAS No. 5334-30-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PP 3
PP 3 (Compound 3) is an EGFR tyrosine kinase inhibitor with an IC 50 of 2.7 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5334-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108484.
PP30
PP30 is an antimicrobial peptide found in Pteromalus puparum. It has antibacterial activity, but no activity against fungi. Synonyms: Tyr-Val-Pro-Pro-Val-Gln-Lys-Pro-His-Pro-Asn-Gly-Pro-Lys-Phe-Pro-Thr-Phe-Pro. Grade: ≥97%. Molecular formula: C105H151N25O24. Mole weight: 2147.51.
A negative control for the Src family kinase inhibitor PP2. Inhibits the activity of EGFR kinase at an IC50 = 2.7uM. Group: Biochemicals. Alternative Names: 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine; NSC 1401. Grades: Purified. CAS No. 5334-30-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PP58
PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR , FGFR and Src family activities with nanomolar IC 50 values. Uses: Scientific research. Group: Signaling pathways. CAS No. 212391-58-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18622.
pp60 c-src (521-533) (phosphorylated)
pp60 c-src (521-533) (phosphorylated). Group: Biochemicals. Grades: Purified. CAS No. 149299-77-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
pp60 c-src (521-533) (phosphorylated)
pp60 c-src (521-533) (phosphorylated), the pp60 c-src carboxy-terminal phosphoregulatory peptide phosphorylated at Tyr527, participates in the regulation of kinase activity through binding intramolecularly or intermolecularly to the SH2 domain of the pp60 c-src protein. Synonyms: H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH; L-threonyl-L-seryl-L-threonyl-L-alpha-glutamyl-L-prolyl-L-glutaminyl-O4-phosphono-L-tyrosyl-L-glutaminyl-L-prolyl-glycyl-L-alpha-glutamyl-L-asparagyl-L-leucine; L-Leucine, L-threonyl-L-seryl-L-threonyl-L-a-glutamyl-L-prolyl-L-glutaminyl-O-phosphono-L-tyrosyl-L-glutaminyl-L-prolylglycyl-L-a-glutamyl-L-asparaginyl-; Thr-Ser-Thr-Glu-Pro-Gln-O-Phosphono-Tyr-Gln-Pro-Gly-Glu-Asn-Leu-OH. Grade: >99%. CAS No. 149299-77-4. Molecular formula: C62H95N16O28P. Mole weight: 1543.48.
pp60v-src Autophosphorylation site
pp60v-src Autophosphorylation site is a synthetic peptide. pp60v-src Autophosphorylation site can be used for various biochemical studies [1]. Uses: Scientific research. Group: Peptides. CAS No. 81493-98-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3744.
PPA
PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 452072-22-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141664.
A highly potent, selective and irreversible thrombin inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 142036-63-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PPACK TFA
PPACK TFA is a plasminogen activator (rt-PA) inhibitor. PPACK TFA can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK TFA also inhibits the binding of rt-PA to plasma protease inhibitors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 157379-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122542B.
PPADS tetrasodium
PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC 50 s ranging from 1 to 2.6 μM. PPADS tetrasodiuma blocks native P2Y2-like ( IC 50 ~0.9 mM) and recombinant P2Y4 ( IC 50 ~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca 2+ exchanger in guinea pig airway smooth muscle [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 192575-19-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-101044.
PPADS Tetrasodium
PPADS Tetrasodium. Group: Biochemicals. Alternative Names: 4-[2-[4-Formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]diazenyl]-1,3-benzenedisulfonic Acid Tetrasodium Salt. Grades: Highly Purified. CAS No. 192575-19-2. Pack Sizes: 25mg. Molecular Formula: C14H10N3Na4O12PS2, Molecular Weight: 599.299999999999. US Biological Life Sciences.
Worldwide
PPADS tetrasodium salt
PPADS tetrasodium salt. Group: Biochemicals. Grades: Purified. CAS No. 192575-19-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PPAHV
PPAHV. Group: Biochemicals. Grades: Purified. CAS No. 175796-50-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pp-AMP1
Pp-AMP1 is a chitin-binding peptide and an antimicrobial peptide found in Phyllostachys edulis (Japanese Bamboo Shoots, ?Phyllostachys pubescens), and has activity against gram-negative bacteria, gram-positive bacteria and fungi. Synonyms: ?Phyllostachys pubescens antimicrobial peptide-1. Grade: >98%.
Pp-AMP2
Pp-AMP2 is a chitin-binding peptide and an antimicrobial peptide found in Phyllostachys edulis (Japanese Bamboo Shoots, ?Phyllostachys pubescens), and has activity against gram-negative bacteria, gram-positive bacteria and fungi. Synonyms: ?Phyllostachys pubescens antimicrobial peptide-2. Grade: >98%.
PPAR Agonist IX, GQ-16
The PPAR Agonist IX, GQ-16 controls the biological activity of PPAR. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable thiazolidinedione that acts as a PPARg-selective agonist (Ki=160nM) and blocks Cdk-5-mediated Ser273 phosphorylation by stabilizing PPARg b-sheet structure, exhibiting no detectable activity towards PPARa, PPARd, or RXRa. Although a weaker PPAPg agonist than Thiazolidinediones (TZDs) family rosiglitazone (Max. fold of transactivation induction =8.57 and 24.8 with 10uM respective compound in U-937 reporter assays), GQ-16 can be safely administered at a higher dosage (20mg/kg/day; oral gavage) in mice to achieve similar in vivo efficacy as rosiglitazone (4mg/kg/day; o.g.) without adverse side effects commonly seen with TZDs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.