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| Product | Description | |
|---|---|---|
| Pomalidomide | 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione. CAS No. 19171-19-8. Product ID: 8-04790. Molecular formula: C13H11N3O4. Mole weight: 273.25. Purity: 0.99. |  |
| Pomalidomide | Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. Group: Biochemicals. Alternative Names: 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; Actimid; CC 4047; IMiD 3. Grades: Highly Purified. CAS No. 19171-19-8. Pack Sizes: 500mg, 1g, 5g. Molecular Formula: C??H??N?O?, Molecular Weight: 273.24. US Biological Life Sciences. |  Worldwide |
| Pomalidomide | Promotes degradation of transcription factors SALL4, IKZF1 and IKZF3. Synonyms: CC4047; CC 4047; CC-4047; Pomalidomide. Brand name: Pomalyst. Grades: ≥99% (HPLC). CAS No. 19171-19-8. Molecular formula: C13H11N3O4. Mole weight: 273.24. |  |
| Pomalidomide 4'-alkylC4-acid | Pomalidomide 4'-alkylC4-acid (linker16) is a E3 Ligase Ligand-Linker Conjugate. Pomalidomide 4'-alkylC4-acid can be used for conjugation to a target protein ligand [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225940-48-5. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-131886. |  |
| Pomalidomide 4'-alkylC5-acid | Pomalidomide 4'-alkylC5-acid (Example 3) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC5-acid can be used in the synthesis of PROTAC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225940-49-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130737. | |
| Pomalidomide 4'-PEG3-azide | Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach [1]. Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271036-46-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130652. | |
| Pomalidomide-amino-PEG4-NH2 hydrochloride | Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2331259-45-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-138859A. | |
| Pomalidomide-C2-NH2 | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Synonyms: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. Grades: > 98%. CAS No. 1957235-66-3. Molecular formula: C15H16N4O4. Mole weight: 316.31. | |
| Pomalidomide-C2-NH2 hydrochloride | Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 15 hydrochloride. CAS No. 2305369-00-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-128846A. | |
| Pomalidomide-C3-adavosertib | Pomalidomide-C3-adavosertib is a rapid and selective PROTAC Wee1 degrader (IC50=3.58 nM). Pomalidomide-C3-adavosertib shows anti-cancer cell proliferation activity, and induces apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414418-49-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133618. | |
| Pomalidomide-C4-NH2 | Pomalidomide-C4-NH2 is a synthetic E3 ligase ligand-linker conjugate that incorporates Pomalidomide-based CRBN ligands and linkers used in PROTAC technology. Synonyms: 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione; 4-[(4-Aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-; Thalidomide-NH-C4-NH2. Grades: ≥95%. CAS No. 1957236-34-8. Molecular formula: C17H20N4O4. Mole weight: 344.37. | |
| Pomalidomide Impurity 1 | An impurity of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Grades: > 95%. Molecular formula: C16H10N2O6. Mole weight: 326.27. | |
| Pomalidomide Impurity 10 | An impurity of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Grades: > 95%. Molecular formula: C10H16N2O4. Mole weight: 228.25. | |
| Pomalidomide Impurity 20 | Pomalidomide Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1001852-10-3. Molecular formula: C13H11N3O7. Mole weight: 321.25. Catalog: APB1001852103. |  |
| Pomalidomide Impurity 3 | An impurity of Pomalidomide which is a second generation immunomodulator and antineoplastic agent. Synonyms: Isoasparagine; 498-25-9; 3,4-Diamino-4-oxobutanoic acid; DL-Isoasparagine; DL-alpha-Asparagine; H-Asp-NH; H-Isoasn-OH; L-Isoasparagine; H-D-Isoasn-OH; D-Isoasparagine; 3,4-Diamino-4-oxobutyric acid; 3-amino-3-carbamoylpropanoic acid; alpha-asparagine; aspartic 1-amide; H-D-Asp-NH; 3-aminosuccinamic acid; 3,4-Diamino-4-oxobutanoic acid #; NSC528893; Aminobernsteinsaureamid; DL-aspartic 1-amide; aspartic acid 1-amide; NoName_589; Succinamic acid, 3-amino-; SCHEMBL1072994; SCHEMBL11049326; 3-amino-3-carbamoylpropanoicacid; CHEBI:49010; DTXSID90901471; PMLJIHNCYNOQEQ-UHFFFAOYSA-N; Butanoic acid, 3,4-diamino-4-oxo-; AKOS014226960; NSC 528893; NSC-528893; FT-0638751; FT-0697947; EN300-182732; Q27121435. Grades: > 95%. CAS No. 498-25-9. Molecular formula: C5H10N2O3. Mole weight: 146.15. | |
| Pomalidomide Impurity 4 | An impurity of Pomalidomide which is an immunomodulatory antineoplastic agent for the treatment of multiple myeloma. Synonyms: DL-GLUTAMINE. Grades: > 95%. CAS No. 585-21-7. Molecular formula: C5H10N2O3. Mole weight: 146.15. | |
| Pomalidomide Impurity 5 | An impurity of Pomalidomide which inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Synonyms: 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione; 4-Nitrothalidomide; 3-Nitrothalidomide; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-nitro-; 2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindole-1,3-dione; Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-nitro-; OH13HKS17A; CHEMBL370441; C13H9N3O6; MFCD01748356; 2-(2,6-Dioxo-3-piperidinyl)-4-nitro-1H-isoindole-1,3(2H)-dione; 2-(2,6-dioxopiperidin-3-yl)-4-nitro-1H-isoindole-1,3(2H)-dione; N-(2,6-Dioxo-3-piperidyl)-3-nitrophthalimide; Nitrothalidomide; 3-(1',3'-Dioxo-4'-nitroisoindolinyl-2')-2,6-dioxopiperidine. Grades: > 95%. CAS No. 19171-18-7. Molecular formula: C13H9N3O6. Mole weight: 303.23. | |
| Pomalidomide Impurity 6 | An impurity of Pomalidomide which a derivative of thalidomide with antineoplastic effect. Grades: > 95%. Molecular formula: C21H14N4O6. Mole weight: 418.37. | |
| Pomalidomide Impurity 7 | An impurity of Pomalidomide which is a second generation immunomodulator and antineoplastic agent. Synonyms: Hydrolyzed Pomalidomide M10; 4-Amino-γ-(aminocarbonyl)-1,3-dihydro-1,3-dioxo-2H-isoindole-2-butanoic Acid. Grades: > 95%. CAS No. 918314-45-1. Molecular formula: C13H13N3O5. Mole weight: 291.27. | |
| Pomalidomide Impurity 8 | Pomalidomide Impurity 8 is an impurity of pomalidomide, which is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. Synonyms: CC-8017; CC 8017; CC8017; 2-(4-amino-1,3-dioxoisoindolin-2-yl)-4-carbamoylbutanoic acid. Grades: >98%. CAS No. 2635-64-5. Molecular formula: C13H13N3O5. Mole weight: 291.26. | |
| Pomalidomide Impurity 9 | An impurity of Pomalidomide which a derivative of thalidomide with antineoplastic effect. Grades: > 95%. Molecular formula: C10H18N2O5. Mole weight: 246.27. | |
| Pomalidomide-PEG1-C2-NH2 | Pomalidomide-PEG1-C2-NH2 is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: Thalidomide-NH-PEG1-NH2; 4-((2-(2-aminoethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-{[2-(2-Aminoethoxy)ethyl]amino}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[2-(2-aminoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-. Grades: ≥95%. CAS No. 2138439-12-8. Molecular formula: C17H20N4O5. Mole weight: 360.36. | |
| Pomalidomide-PEG2-azide | Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology [1]. Pomalidomide-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2267306-14-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-137537. | |
| Pomalidomide-PEG2-C2-NH2 | Pomalidomide-PEG2-C2-NH2 is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: Thalidomide-NH-PEG2-NH2; 4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 4-({2-[2-(2-Aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-; 4-({2-[2-(2-aminoethoxy)ethoxy]ethyl}amino)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione; Thalidomide-NH-PEG2-C2-NH2. Grades: ≥95%. CAS No. 2093416-32-9. Molecular formula: C19H24N4O6. Mole weight: 404.42. | |
| Pomalidomide-PEG3-azide | Pomalidomide-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology [1]. Pomalidomide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2267306-15-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-137538. | |
| Pomalidomide-PEG3-C2-NH2 hydrochloride | Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 3 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Molecular formula: C21H29ClN4O7. Mole weight: 484.93. | |
| Pomalidomide-PEG3-C2-NH2 TFA | Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker. Pomalidomide-PEG3-C2-NH2 TFA can be used for the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 5 TFA; E3 ligase Ligand-Linker Conjugates 30 TFA. CAS No. 2414913-97-4. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-128716A. | |
| Pomalidomide-PEG4-azide | Pomalidomide-PEG4-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology [1]. Pomalidomide-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271036-47-4. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-141015. | |
| Pomalidomide-PEG4-C2-NH2 hydrochloride | Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2357105-92-9. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-112599B. | |
| Pomalidomide-PEG5-CO2H | Pomalidomide-PEG5-CO2H is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal carboxylic acid for reactivity with an amine on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid. Grades: ≥98%. CAS No. 2139348-63-1. Molecular formula: C26H35N3O11. Mole weight: 565.57. | |
| Pomegranate Extract | Pomegranate extract is prepared from the peel and seeds of the pomegranate the family Punicaceae which includes only one genus and two species. Pomegranate peel extract contains punicalagins, ellagic acid and pomegranate polyphenols, pomegranate extract offers abundant benefits for the cardiovascular system by preventing damage to arterial walls, promoting healthy blood pressure levels, improving blood flow to the heart, and preventing or reversing atherosclerosis. Group: Others. Mole weight: 1084.72. Pomegranate Extract; Punica granatum Linn. Cat No: EXTC-012. |  |
| Pomegranate Powder | Pomegranate powder is made from fruit of fresh Pomegranate (punica granatum), Pomegranate juice powder contains Ellagic acid, polyphenols, glycosides, with effect of anti-cancer and anti-oxidant. Besides pomegranate powder also have many kinds of untrients with good water-solublility, widely used in foods and beverages. Group: Others. Pomegranate Powder; Punica granatum L. Cat No: EXTC-095. | |
| Pomegranate Powder- Indian material | Pomegranate Powder- Indian material. |  CA, FL & NJ |
| Pomiferin | Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC , with an IC 50 of 1.05 μM, and also potently inhibits mTOR ( IC 50 , 6.2 μM). Uses: Scientific research. Group: Natural products. Alternative Names: NSC 5113. CAS No. 572-03-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4315. | |
| Pomiferin | Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 μM). Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 572-03-2. Molecular formula: C25H24O6. Mole weight: 420.45. Product ID: ACM572032-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Pomolic acid β-D-glucopyranosyl ester | Pomolic acid β-D-glucopyranosyl ester. Group: Biochemicals. CAS No. 83725-24-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PON1 Activator (ZNPA, (Z)-2,3-bis (4-nitrophenyl)-acrylonitrile) | A cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50=1uM) and inducer of PON1 enzymatic activity (>3-fold at 5um) when compared to resveratrol. However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cytochrome P4501A1 (CYP1A1). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ponalrestat | Ponalrestatis an aldose reductase inhibitor originator byAstraZeneca. It can block the conversion of glucose to sorbitol. Ponalrestatis shows selectivity for aldose reductase 2 over aldose reductase 1 with Ki values of 7.7 nM and 60 μM. Phase III for the treatment of diabetes was discontinued. Uses: Diabetes. Synonyms: Ponalrestat, ICI-128436; ICI 128436; ICI128436; MK-538; MK 538; MK538. Brand name: Statil; Statyl. QJ0339; QJ0339; QJ-0339; 2-(3-(4-bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid. Grades: 98%. CAS No. 72702-95-5. Molecular formula: C17H12BrFN2O3. Mole weight: 391.20. | |
| Ponalrestat | Ponalrestat Inhibitor. Uses: Scientific use. Product Category: T2013. CAS No. 72702-95-5. |  |
| Ponatinib | Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP24534. CAS No. 943319-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12047. | |
| Ponatinib | Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively. Synonyms: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; AP24534; AP-24534; AP 24534; Ponatinib Brand name: Iclusig. Grades: >98%. CAS No. 943319-70-8. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| Ponatinib, Free Base (AP24534) | Ponatinib is a novel potent, orally available small molecule multitargeted kinase inhibitor. Ponatinib inhibits both native and mutant BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors. Ponatinib is the active ingredient in the drug product sold under the trade name Iclusig®, currently approved in at least one country for use in patients with chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia. Group: Biochemicals. Alternative Names: 3- (2-Imidazo[1, 2-b]pyridazin-3-ylethynyl) -4-methyl-N-[4-[ (4-methyl-1-piperazinyl) methyl]-3- (trifluoromethyl) phenyl]benzamide; AP 24534; Iclusig. Grades: Highly Purified. CAS No. 943319-70-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C29H27F3N6O, Molecular Weight: 532.56. US Biological Life Sciences. | Worldwide |
| Ponatinib hydrochloride | Ponatinib hydrochloride is an oral drug for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). It is a multi-targeted tyrosine-kinase inhibitor. It has potential antiangiogenic and antineoplastic activities. It inhibits unmutated and all mutated forms of Bcr-Abl, including T315I, the highly drug therapy-resistant missense mutation of Bcr-Abl. It inhibits the tyrosine kinase receptor TIE2 and FMS-related tyrosine kinase receptor-3 (Flt3). It was developed by Ariad Pharm and has been listed. Uses: Ponatinib hydrochloride is an oral drug for the treatment of chronic myeloid leukemia (cml) and philadelphia chromosome-positive (ph+) acute lymphoblastic leukemia (all). it has potential antiangiogenic and antineoplastic activities. Synonyms: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide hydrochloride; AP24534; AP-24534; AP 24534; Ponatinib HCl; Ponatinib hydrochloride trade name Iclusig. Grades: >98%. CAS No. 1114544-31-8. Molecular formula: C29H28ClF3N6O. Mole weight: 569.03. | |
| Ponatinib hydrochloride | Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC 50 s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl , PDGFRα , VEGFR2 , FGFR1 , and Src , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP24534 hydrochloride. CAS No. 1114544-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108766. | |
| Ponatinib Impurity 2 | Ponatinib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(dibromomethyl)-4-nitro-2-(trifluoromethyl)benzene. CAS No. 122947-77-7. Molecular formula: C8H4Br2F3NO2. Mole weight: 362.93. Catalog: APB122947777. | |
| Ponatinib Impurity 5 | Ponatinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1255099-13-8. Molecular formula: C11H10O2. Mole weight: 174.2. Catalog: APB1255099138. | |
| Ponatinib Impurity 8 | Ponatinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1001203-03-7. Molecular formula: C10H8O2. Mole weight: 160.17. Catalog: APB1001203037. | |
| Ponatinib Tris-Hydrochloride | Ponatinib Tris-Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1232836-25-7. Molecular formula: C29H30Cl3F3N6O. Mole weight: 641.95. Catalog: APB1232836257. | |
| Ponceau 3r | Ponceau 3r. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PONCEAU 3R;PONCEAU-3R STAIN;3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-2,7-naphthalenedisulphonicacid,dis;3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-2,7-naphthalenedisulphonicacid,disod;7-naphthalenedisulfonicacid,3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-dis. Product Category: Heterocyclic Organic Compound. Appearance: Dark red crystals or red powder. CAS No. 3564-9-8. Molecular formula: C19H16N2Na2O7S2. Mole weight: 494.45. Purity: 0.96. IUPACName: disodium (4Z)-3-oxo-4-[(2,4,5-trimethylphenyl)hydrazinylidene]naphthalene-2,7-disulfonate. Density: g/cm³. Product ID: ACM3564098. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ponceau 3R | analytical standard. Group: Colorant standardsdyes & metabolitesdyes & metabolites. Alternative Names: FD&C Red No. 1, Usacert Red No. 1, D and C Red 15, Ext D and C Red No. 15, Japan Red 1, Ponceau 3R Lake, Japan Red 502, FD and C Red No. 1, Dolkwal Ponceau 3R, C.I. 16155, Maple Ponceau 3R, Ponceau 3R sodium salt, FDC Red 1, Disodium 3-hydroxy-4-[(2,4,5-trimethylphenyl)azo]-2,7-naphthalenedisulfonate,2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[(2,4,5-trimethylphenyl)azo]-, disodium salt (9CI), Scarlet F, Ponceau 3RN, Ponceau 3R (6CI). | |
| Ponceau 4R | Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 18; New Coccine. CAS No. 2611-82-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0193. | |
| Ponceau 4R | analytical standard. Group: Colorant standards. | |
| Ponceau 6R | analytical standard. Group: Colorant standards. | |
| PONCEAU 6R | PONCEAU 6R. CAS No. 5850-44-2. Product ID: PE-0218. Molecular formula: C20H10N2Na4O13S4. Mole weight: 706.518. Category: Colorant Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Semi-solid Dosage Form; Suppository Bases; Colorant Excipients; PONCEAU 6R; PE-0218; C20H10N2Na4O13S4; 5850-44-2; 5850-44-2. Purity: 0.98. EC Number: 227-454-4. Solubility: water, 3243 mg/L @ 25 °C (est). Density: 1.46 g/cm3. |  |
| Ponceau S | Ponceau S (Acid Red 112) is a non-specific protein dye commonly used as a stain for Western blot. Ponceau S is used in an acidic aqueous solution that is compatible with antibody-antigen binding and dyes the proteins on the membrane red [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 112. CAS No. 6226-79-5. Pack Sizes: 500 mg. Product ID: HY-12489. | |
| Ponceau S (C.I.27195) | 25g Pack Size. Group: Stains & Indicators. Formula: C22H12N4Na4O13S4. CAS No. 6226-79-5. Prepack ID 43797916-25g. Molecular Weight 760.57. See USA prepack pricing. |  |
| Ponceau S ≥90% (Dye content) | Ponceau S ≥90% (Dye content). Group: Biochemicals. Alternative Names: 3-Hydroxy-4[2-sulfo-4- (4-sulfophenylazo) phenylazo]-2, 7-naphthalenedisulfonic acid tetrasodium salt. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Ponceau Solution 0.1 % (w/v) in 5% (w/v) acetic acid | 5lt Pack Size. Group: Analytical Reagents, Biochemicals, Buffers, Diagnostic Raw Materials, Organics, Stains & Indicators. Formula: C22H12N4Na4O13S4. CAS No. 6226-79-5. Prepack ID 90029153-5lt. Molecular Weight 760.57. See USA prepack pricing. | |
| Ponceau ss | Ponceau ss. Uses: Designed for use in research and industrial production. Additional or Alternative Names: C.I.Acid Red 150; PONCEAU SS; ACID RED 150. CAS No. 6226-78-4. Molecular formula: C22H14N4Na2O7S2. Mole weight: 556.48. Purity: Dye content, 80%. IUPACName: disodium (4Z)-3-oxo-4-[(4-phenyldiazenylphenyl)hydrazinylidene]naphthalene-2,7-disulfonate. Canonical SMILES: C1=CC=C(C=C1)N=NC2=CC=C(C=C2)NN=C3C4=C(C=C(C=C4)S(=O)(=O)[O-])C=C(C3=O)S(=O)(=O)[O-].[Na+].[Na+]. ECNumber: 228-318-7. Product ID: ACM6226784. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ponceau SX | analytical standard. Group: Colorant standardsdyes & metabolitesdyes & metabolites. | |
| PONCEAU SX | PONCEAU SX. CAS No. 4548-53-2. Product ID: PE-0219. Molecular formula: C18H14N2Na2O7S2. Mole weight: 480.423. Category: Colorant Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Semi-solid Dosage Form; Suppository Bases; Colorant Excipients; PONCEAU SX; PE-0219; C18H14N2Na2O7S2; 4548-53-2; 4548-53-2. Purity: 0.98. EC Number: 224-909-9. Solubility: water, 1580 mg/L @ 25 °C (est). | |
| Ponceau Xylidine | analytical standard. Group: Colorant standards. | |
| Poncirin | Poncirin. Group: Biochemicals. Alternative Names: Citrifolioside. Grades: Plant Grade. CAS No. 14941-08-3. Pack Sizes: 20mg. Molecular Formula: C28H34O14, Molecular Weight: 594.561. US Biological Life Sciences. | Worldwide |
| Poncirin | analytical standard. Group: Herbal medicinal products standards. | |
| Poncirin | Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freunds Adjuvant (CFA)-induced inflammatory pain models [1]. Uses: Scientific research. Group: Natural products. CAS No. 14941-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2258. | |
| Ponericin-G1 | Ponericin-G1 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against fungi. Synonyms: Gly-Trp-Lys-Asp-Trp-Ala-Lys-Lys-Ala-Gly-Gly-Trp-Leu-Lys-Lys-Lys-Gly-Pro-Gly-Met-Ala-Lys-Ala-Ala-Leu-Lys-Ala-Ala-Met-Gln-NH2. Molecular formula: C148H239N43O33S2. Mole weight: 3212.93. | |
| Ponericin-G2 | Ponericin-G2 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against fungi. Synonyms: Gly-Trp-Lys-Asp-Trp-Leu-Lys-Lys-Gly-Lys-Glu-Trp-Leu-Lys-Ala-Lys-Gly-Pro-Gly-Ile-Val-Lys-Ala-Ala-Leu-Gln-Ala-Ala-Thr-Gln-NH2. Grades: >96%. Molecular formula: C155H249N43O37. Mole weight: 3306.96. | |
| Ponericin-G3 | Ponericin-G3 is an antibacterial peptide isolated from Pachycondyla goeldii. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Molecular formula: C157H254N44O37S. Mole weight: 3382.09. | |
| Ponericin-G4 | Ponericin-G4 is an antibacterial peptide isolated from Pachycondyla goeldii. Synonyms: Asp-Phe-Lys-Asp-Trp-Met-Lys-Thr-Ala-Gly-Glu-Trp-Leu-Lys-Lys-Lys-Gly-Pro-Gly-Ile-Leu-Lys-Ala-Ala-Met-Ala-Ala-Ala-Thr-NH2. Molecular formula: C145H232N38O37S2. Mole weight: 3163.80. | |
| Ponericin-G5 | Ponericin-G5 is an antibacterial peptide isolated from Pachycondyla goeldii. Synonyms: Gly-Leu-Lys-Asp-Trp-Val-Lys-Ile-Ala-Gly-Gly-Trp-Leu-Lys-Lys-Gly-Pro-Gly-Ile-Leu-Lys-Ala-Ala-Met-Ala-Ala-Ala-Thr-Gln-NH2. Grades: >97%. Molecular formula: C138H228N38O33S. Mole weight: 2979.64. | |
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