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| Product | Description | |
|---|---|---|
| PR-104 | PR-104 is a non-toxic, small-molecule, hypoxia-activated, 3,5-dinitrobenzamide nitrogen mustard pre-prodrug with potential antitumor activity. Upon intravenous administration, PR-104 is converted by systemic phosphatases to the alcohol intermediate PR-104A, which is reduced to form the active DNA-crosslinking mustard species hydroxylamine PR-104H intracellularly under hypoxic conditions. PR-104H specifically crosslinks hypoxic tumor cell DNA, resulting in the inhibition of DNA repair and synthesis, cell-cycle arrest, and apoptosis in susceptible hypoxic tumor cell populations while sparing normoxic tissues. Synonyms: PR 104; PR104; 2- ( (2-Bromoethyl) (2, 4-dinitro-6- ( (2- (phosphonooxy) ethyl) carbamoyl) phenyl) amino) ethyl methanesulfonate; Benzamide, 2-[(2-bromoethyl)[2-[(methylsulfonyl)oxy]ethyl]amino]-3,5-dinitro-N-[2-(phosphonooxy)ethyl]-. Grades: ≥97%. CAS No. 851627-62-8. Molecular formula: C14H20BrN4O12PS. Mole weight: 579.27. |  |
| PR-104 | PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851627-62-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16405. |  |
| PR 37454 | PR 37454 is a polyether antibiotic produced by Streptomyces gypseus DS 27461. It is active against gram-positive bacteria and coccidium. Synonyms: PR-37454; PR37454. Molecular formula: C48H82O18. Mole weight: 947.15. | |
| PR 39 (porcine) | PR 39 (porcine) is a gene-encoded, proline-arginine-rich porcine antimicrobial peptide with multiple biological functions. It might function in the inflammatory milieu not only to kill bacteria, but also to aid in modulating the viability of inflammatory cells by regulating apoptosis. Uses: Anti-bacterial agents. Synonyms: PR39 (porcine); PR-39 (porcine); H-RRRPRPPyl PRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2; H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2; L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-tyrosyl-L-leucyl-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-leucyl-L-prolyl-L-prolyl-L-arginyl-L-isoleucyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-phenylalanyl-L-prolyl-L-prolyl-L-arginyl-L-phenylalanyl-L-prolinamide. Grades: >98%. CAS No. 139637-11-9. Molecular formula: C229H346N70O40. Mole weight: 4719.74. | |
| PR 619 | PR 619. Group: Biochemicals. Alternative Names: Thiocyanic Acid C,C'-(2,6-Diamino-3,5-pyridinediyl) Ester; Thiocyanic Acid C,C'-(2,6-Diamino-3,5-pyridinediyl) Ester; 2,6-Diamino-3,5-dithiocyanopyridine. Grades: Highly Purified. CAS No. 2645-32-1. Pack Sizes: 25mg. Molecular Formula: C7H5N5S2, Molecular Weight: 223.28. US Biological Life Sciences. |  Worldwide |
| PR-619 | Broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and colorectal cancer cells. Stabilizes microtubule network in oligodendroglial cells. Synonyms: PR-619; PR 619; PR619. CAS No. 2645-32-1. Molecular formula: C7H5N5S2. Mole weight: 223.272. | |
| Pracinostat | Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies. Group: Biochemicals. Alternative Names: (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxyacrylamide; (E)-3-[2-Butyl-1-(2-diethylaminoethyl)-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide; Kaempferol 3-O- β-D-(6-E-p-Coumaroylglucoside); SB 939; SB939; (2E)-3-[2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-2-propenamide. Grades: Highly Purified. CAS No. 929016-96-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Pracinostat | Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors. Synonyms: SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat. Grades: >98%. CAS No. 929016-96-6. Molecular formula: C20H30N4O2. Mole weight: 358.486. | |
| Practolol | Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6673-35-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119802. | |
| Practolol | Practolol is a selective beta-1 adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. lt competes with adrenergic neurotransmitters such as catecholamines for binding at sympathetic receptor sites. lt inhibits the effects of the catecholamines epinephrine and norepinephrine and decreases heart rate, cardiac output, and systolic and diastolic blood pressure. lt has anti-hyperstensive activity. Uses: Practolo has been used in the emergency treatment of cardiac arrhythmias. lt has anti-hyperstensive activity. Synonyms: Practolol; Dalzic; Eraldin; Teranol; ICI 50172; Eralzdin Practolol; ICI 50172; ICI-50172; ICI50172; Practolol; Practolol, Eralzdin; Practololum;N-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide;rac Practolol; (±)-Practolol; 1-(4-Acetamidophenoxy)-3-isopropylamino-2-propanol; Dalzic; Eraldin; 4'-[2-Hydroxy-3-(isopropylamino)propoxy]acetanilide; ICI-50172; ICI50172. Grades: 98%. CAS No. 6673-35-4. Molecular formula: C14H22N2O3. Mole weight: 266.34. | |
| Pradefovir mesylate | Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a K m of 60 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Remofovir mesylate. CAS No. 625095-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112690A. | |
| Pradigastat | Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC 50 at 0.157 μM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC 50 of 5 μM, 1.66μM, 3.34μM and 0.973μM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCQ-908. CAS No. 956136-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16278. | |
| Pradimicin A | Pradimicin A is an antibiotic produced by Actinomadura hibisca. It has strong antifungal and yeast activity. Synonyms: Pradimicin A|117704-65-1|CHEBI:8349|(R)-2-((5S,6S)-1,6,9,14-Tetrahydroxy-5-(((2S,3R,4S,5S,6R)-3-hydroxy-6-methyl-5-(methylamino)-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-11-methoxy-3-methyl-8,13-dioxo-5,6,8,13-tetrahydrobenzo[a]tetracene-2-carboxamido)propanoic acid|Pradimicin-A|BMY 28567|BMY-28567|(2R)-2-[[(5S,6S)-1,6,9,14-tetrahydroxy-5-[(2S,3R,4S,5S,6R)-3-hydroxy-6-methyl-5-(methylamino)-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-11-methoxy-3-methyl-8,13-dioxo-5,6-dihydrobenzo[a]tetracene-2-carbonyl]amino]propanoic acid|(2R)-2-[[(5S,6S)-1,6,9,14-tetrahydroxy-5-[(2S,3R,4S,5S,6R)-3-hydroxy-6-methyl-5-(methylamino)-4-[(2S,3R,4S,5R)-3,4,5-trihydroxytetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-11-methoxy-3-methyl-8,13-dioxo-5,6-dihydrobenzo[a]tetracene-2-carbonyl]amino]propanoic acid|Pradimicin A & Pectin|Pradimicin A & Glycogen |SCHEMBL499208|CHEMBL1673205|GLXC-25326|HY-132191|CS-0169773|Q27108053| (2R) -2- ( { [ (5S, 6S) -1, 6, 9, 14-tetrahydroxy-5- { [ (2S, 3R, 4S, 5S, 6R) -3-hydroxy-6- methyl -5- ( methyl amino) -4- { [ (2S, 3R, 4S, 5R) -3, 4, 5-trihydroxytetrahydro-2H-pyran-2-yl] oxy} tetrahydro-2H-pyran-2-yl] oxy} -11-methoxy-3- methyl -8, 13-dioxo-5, 6, 8, 13-tetrahydrobenzo [a] tetracen-2-yl] carbonyl} amino) propanoic acid|D-Alanine, N-[[(5S,6S)-5-[[4,6-dideoxy-4-(methylamino)-3-O-.beta.-D-xylopyranosyl-.beta.-D-galactopyranosyl]oxy]-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo[a]naphthacen-2-yl]carbonyl]-. Grades: ≥98% (HPLC). CAS No. 117704-65-1. Molecular formula: C40H44N2O18. Mole weight: 840.78. | |
| Pradimicin b | Heterocyclic Organic Compound. Alternative Names: Pradimicin B;BMY-28634;N-[[[(5S)-5-[[4,6-Dideoxy-4-(methylamino)-β-D-galactopyranosyl]oxy]-5,6,8,13-tetrahydro-1,6β,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo[a]naphthacen]-2-yl]carbonyl]-D-alanine. CAS No. 117704-66-2. Molecular formula: C35H36N2O14. Mole weight: 708.669. Catalog: ACM117704662. |  |
| Pradimicin B | Pradimicin B is an antibiotic produced by Actinomadura hibisca. It has strong antifungal and yeast activity. CAS No. 117704-66-2. Molecular formula: C35H36N2O14. Mole weight: 708.66. | |
| Pradimicin L | Pradimicin L is an antibiotic produced by Actinomadura verrucosospora subsp. neohibisca. It has antifungal activity. Grades: >98%. CAS No. 142062-87-1. Molecular formula: C41H46N2O19. Mole weight: 870.80. | |
| Pradimicin M | Pradimicin M is an antibiotic produced by Actinomadura hibisca. α-glycosidase and β-galactosidase inhibitor. Synonyms: 11-O-Demethylpradinone; (5S,6S)-1,5,6,9,11,14-hexahydroxy-3-methyl-8,13-dioxo-5,6-dihydrobenzo[a]tetracene-2-carboxylic acid. CAS No. 132971-63-2. Molecular formula: C24H16O10. Mole weight: 464.38. | |
| Pradimicin Q | Pradimicin Q is an antibiotic produced by Actinomadura verrucosospora subsp. neohibisca R 103-3. The cytotoxicity (IC50) to human colon HCT-116 cells and murine melanoma B16-F10 cells are 75 and 100 μg/mL, respectively. Synonyms: Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-1,5,7,9,11,14-hexahydroxy-3-methyl-8,13-dioxo-. CAS No. 141869-53-6. Molecular formula: C24H16O10. Mole weight: 464.38. | |
| Pradimicin T1 | Pradimicin T1 is an antibiotic produced by Actinomyces AA 3798. It has activity against filamentous fungi and yeast-like fungi. Synonyms: Glycine, N-((5-((6-deoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-3-methyl-8,13-dioxo-11-(beta-L-xylopyranosyloxy)benzo(a)naphthacen-2-yl)carbonyl)-, (5S-trans)-. CAS No. 149598-64-1. Molecular formula: C42H45NO23. Mole weight: 931.80. | |
| Pradimicin T2 | Pradimicin T2 is an antibiotic produced by Actinomyces AA 3798. It has activity against filamentous fungi and yeast-like fungi. Synonyms: Glycine, N-((5-((6-deoxy-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-3-methyl-8,13-dioxo-11-(beta-L-xylopyranosyloxy)benzo(a)naphthacen-2-yl)carbonyl)-, (5S-trans)-. CAS No. 149598-63-0. Molecular formula: C37H37NO19. Mole weight: 799.68. | |
| Pradofloxacin | Pradofloxacin, a third-generation fluoroquinolone antibacterial agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195532-12-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W753904. | |
| Pradofloxacin hydrochloride | Pradofloxacin hydrochloride. Group: Biochemicals. Alternative Names: 8-Cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride; (4aS-cis)-Pradofloxacin hydrochloride. Grades: Highly Purified. CAS No. 195532-14-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H22ClFN4O3. US Biological Life Sciences. | Worldwide |
| Praeruptorin A | Praeruptorin A. Group: Biochemicals. Grades: Plant Grade. CAS No. 73069-27-9. Pack Sizes: 20mg. Molecular Formula: C21H22O7, Molecular Weight: 386.39. US Biological Life Sciences. | Worldwide |
| Praeruptorin A | Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation [1]. Uses: Scientific research. Group: Natural products. CAS No. 73069-27-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6065. | |
| Praeruptorin B | Praeruptorin B. Group: Biochemicals. CAS No. 81740-07-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Praeruptorin B (Anomalin) | Praeruptorin B (Anomalin). Group: Biochemicals. Alternative Names: (+)-Anomalin; (+)-Praeruptorin B. Grades: Plant Grade. CAS No. 73069-28-0. Pack Sizes: 20mg. Molecular Formula: C24H26O7, Molecular Weight: 426.459. US Biological Life Sciences. | Worldwide |
| Praeruptorin C | Praeruptorin C. Group: Biochemicals. CAS No. 72463-77-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Praeruptorin C (Wulongensin A) | Praeruptorin C (Wulongensin A). Group: Biochemicals. Alternative Names: Wulongensin A. Grades: Plant Grade. CAS No. 72463-77-5. Pack Sizes: 20mg. Molecular Formula: C24H28O7, Molecular Weight: 428.475. US Biological Life Sciences. | Worldwide |
| Praeruptorin E | Praeruptorin E. Group: Biochemicals. Grades: Plant Grade. CAS No. 78478-28-1. Pack Sizes: 10mg. Molecular Formula: C24H28O7, Molecular Weight: 428.48. US Biological Life Sciences. | Worldwide |
| Praesorediosic acid | Praesorediosic acid is an aliphatic acid from the lichen parmotrema praesorediosum. Synonyms: ACMC-20mtl9; 2-Furanpentadecanoic acid, 3-carboxy-2,5-dihydro-4-methyl-5-oxo-, (2R)-. CAS No. 130342-70-0. Molecular formula: C21H34O6. Mole weight: 382.49. | |
| Pralatrexate | Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Uses: Aminopterin/ analogs & derivatives; folic acid antagonists. Synonyms: Pralatrexate;Folotyn; 10-Propargyl-10-deazaaminopterin; HSDB 7786; pralatrexato; pralatrexatum; PDX; CHEBI:71223; NSC-754230; UNII-A8Q8I19Q20; Pralatrexate(Folotyn); DTXSID3048578; A8Q8I19Q20; (2S)-2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioic acid; N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-; DTXCID3028504; 146464-95-1 (racemic); NSC754230; NSC 754230; (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid; NCGC00242596-01; (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid. Grades:>98%. CAS No. 146464-95-1. Molecular formula: C23H23N7O5. Mole weight: 477.47. | |
| Pralatrexate | Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a K i of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activities and has the potential for relapsed/refractory T-cell lymphoma treatment [1] [2] [3] [4]. Pralatrexate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 146464-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10446. | |
| Praliciguat | Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC 50 of 197 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IW-1973. CAS No. 1628730-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109039. | |
| Praliciguat | Praliciguat is a soluble guanylate cyclase stimulator, which can enhance NO signal transduction and act as a vasodilator. Synonyms: IW-1973. Grades: ≥98% by HPLC. CAS No. 1628730-49-3. Molecular formula: C21H14F8N6O2. Mole weight: 534.4. | |
| Pralidoxime chloride | Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-PAM chloride. CAS No. 51-15-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1200. | |
| Pralidoxime Chloride | This compound binds to inactivated acetylcholinesterases and is used to combat poisoning from organophosphates and nerve agents. Group: Biochemicals. Alternative Names: 2-[(Hydroxyimino)methyl]-1-methyl-pyridinium Chloride; 2-Formyl-1-methyl-pyridinium Chloride Oxime; 1-Methylpyridinium-2-aldoxime Chloride; 2-PAM Cl; 2-PAM; Protopam Chloride; 2-Pyridinealdoxime Methochloride; Pyridine-2-aldoxime Methochloride. Grades: Highly Purified. CAS No. 51-15-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Pralidoxime iodide | Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 94-63-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 250 mg. Product ID: HY-B1738A. | |
| Prallethrin | Prallethrin. Group: Biochemicals. Alternative Names: 2, 2-Dimethyl-3- (2-methyl-1-propen-1-yl) cyclopropanecarboxylic acid 2-methyl-4-oxo-3-(2-propyn-1-yl)-2-cyclopenten-1-yl ester; trans-(±)-4-Hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-one 2, 2-di methyl -3- (2- methyl propenyl) cyclopropane carboxylate, (8CI); Acetylene C permethrin. Grades: Highly Purified. CAS No. 23031-36-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C19H24O3. US Biological Life Sciences. | Worldwide |
| Pralsetinib | Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC 50 s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-667. CAS No. 2097132-94-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112301. | |
| Pralsetinib | Pralsetinib. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2097132-94-8. Molecular Formula: C27H32FN9O2. Mole Weight: 533.61. Catalog: APB2097132948. |  |
| Pralsetinib impurity 3 | Pralsetinib impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2778223-51-9. Molecular Formula: C18H25N5O3. Mole Weight: 359.43. Catalog: APB2778223519. | |
| Pralsetinib impurity 4 | Pralsetinib impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2778223-52-0. Molecular Formula: C17H23N5O3. Mole Weight: 345.4. Catalog: APB2778223520. | |
| Pralsetinib impurity 5 | Pralsetinib impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2097133-17-8. Molecular Formula: C10H12ClFN4. Mole Weight: 242.68. Catalog: APB2097133178. | |
| Pramipexole | Pramipexole is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104632-26-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0410. | |
| Pramipexole | Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. Uses: Antioxidants; antiparkinson agents; dopamine agonists. Synonyms: SND 919; SND919; SND-919. Grades: >98%. CAS No. 104632-26-0. Molecular formula: C10H17N3S. Mole weight: 211.33. | |
| Pramipexole | Pramipexole. Group: Biochemicals. Grades: Highly Purified. CAS No. 104632-26-0. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C10H17N3S. US Biological Life Sciences. | Worldwide |
| Pramipexole-d3, Dihydrochloride ((S)-4,5,6,7-Tetrahydro-N6-propyl-d3-2,6-benzothiazolediamine, Dihydrochloride) | A labeled dopamine-D2-receptor agonist. Group: Biochemicals. Alternative Names: (S)-4,5,6,7-Tetrahydro-N6-propyl-d3-2,6-benzothiazolediamine, Dihydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Pramipexole-d5 Dihydrochloride | 2H Labeled Compounds. CAS No. 1217601-58-5. Molecular formula: C10H14Cl2N3SD5. Mole weight: 289.28. Catalog: ACM1217601585-1. | |
| Pramipexole dihydrochloride | Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104632-25-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17355. | |
| Pramipexole dihydrochloride | Pramipexole dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 104632-25-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Pramipexole dihydrochloride hydrate | Pramipexole dihydrochloride hydrate is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole dihydrochloride hydrate can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191217-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0410A. | |
| Pramipexole dihydrochloride monohydrate | Pramipexole is a dopamine agonist with Ki values of 3.9, 2.2, 0.5, 5.1 nM for D2S, D2L, D3 and D4 receptors respectively. It has been used for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS). Synonyms: Pramipexole Dihydrochloride Monohydrate; Pramipexole Dihydrochloride; Pramipexole 2HCl Monohydrate; Pramipexole 2HCl H2O. Grades: >98%. CAS No. 191217-81-9. Molecular formula: C10H17N3S.2HCl.H2O. Mole weight: 302.26. | |
| Pramipexole dihydrochloride monohydrate | Pramipexole dihydrochloride monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 191217-81-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Pramipexole Dihydrochloride (Pramipexole, Dopamine D2-like Receptor Agonist, Pramipexole, Dopamine D3 Receptor Agonist, Pramipexole, (S) -N-propyl -4, 5, 6, 7-tetra hydrobenzothiazole-2, 6-diamine Dihydrochloride) | Non-ergot Dopamine receptor agonist with selectivity for the D3 receptor (Ki values are 0.5, 3.3, 3.9 and 3.9nM for D3, D2S, D2L and D4 receptors respectively). Exhibits very low affinity for serotoninergic 5-HT2A and 5-HT2B receptors, as well as D1-type receptors. Shows good solubility in aqueous media (100mM water and 100mM DMSO). Immediate-release (IR) pramipexole dihydrochloride is indicated for the treatment of signs and symptoms of idiopathic Parkinsons disease (PD). It is administered alone (without levodopa) or in combination with levodopa, during the entire progress of the disease, up to an advanced stage. Currently, it is also indicated for the treatment of moderate-to-severe primary restless legs syndrome (RLS). Group: Biochemicals. Grades: Highly Purified. CAS No. 104632-25-9. Pack Sizes: 10mg. Molecular Formula: C??H??N?S 2HCl. US Biological Life Sciences. | Worldwide |
| Pramipexole, Dihydrochloride ((s)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine, Dihydrochloride) | A dopamine-D2-receptor agonist. Group: Biochemicals. Alternative Names: (s)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine, Dihydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Pramipexole Dimer Impurity II | An metabolitic impurity of Pramipexole which is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. Synonyms: Pramipexole C-C Dimer ; (6S)-6-N-[3-[(6S)-2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-1-ethyl-2-methylpropyl]-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine. Grades: > 95%. Molecular formula: C20H32N6S2. Mole weight: 420.65. | |
| Pramipexole Dimer Impurity (Mixture of Diastereomers) | An impurity of Pramipexole which is a dopamine agonist of the non-ergoline class, especially used as D2-receptor agonist which is one of the most classical targets in the treatment of Parkinson's disease. Grades: > 95%. Molecular formula: C20H32N6S2. Mole weight: 420.65. | |
| Pramipexole EP Impurity A | Pramipexole EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106092-09-5. Molecular Formula: C7H11N3S. Mole Weight: 169.25. Catalog: APB106092095. | |
| Pramipexole EP Impurity A (Rac) | Pramipexole EP Impurity A (Rac). Uses: For analytical and research use. Group: Impurity standards. CAS No. 104617-49-4. Molecular Formula: C7H11N3S. Mole Weight: 169.25. Catalog: APB104617494. | |
| Pramipexole EP Impurity B HCl | Pramipexole EP Impurity B HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1802051-36-0. Molecular Formula: C13H24ClN3S. Mole Weight: 289.87. Catalog: APB1802051360. | |
| Pramipexole EP Impurity C | Pramipexole EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6S,6'S)-N6,N6'-(2-methylpentane-1,3-diyl)bis(4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine). CAS No. 1973461-14-1. Molecular Formula: C20H32N6S2. Mole Weight: 420.64. Catalog: APB1973461141. | |
| Pramipexole EP Impurity C (Rac) | Pramipexole EP Impurity C (Rac). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1897440-04-8. Molecular Formula: C20H32N6S2. Mole Weight: 420.64. Catalog: APB1897440048. | |
| Pramipexole EP Impurity D | Pramipexole EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104632-28-2. Molecular Formula: C10H17N3S. Mole Weight: 211.33. Catalog: APB104632282. | |
| Pramipexole EP Impurity D DIHCl | Pramipexole EP Impurity D DIHCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104632-27-1. Molecular Formula: C10H19Cl2N3S. Mole Weight: 284.24. Catalog: APB104632271. | |
| Pramipexole EP Impurity E | Pramipexole EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106006-84-2. Molecular Formula: C10H15N3OS. Mole Weight: 225.31. Catalog: APB106006842. | |
| Pramipexole EP Impurity F | Pramipexole EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104617-76-7. Molecular Formula: C13H23N3S. Mole Weight: 253.41. Catalog: APB104617767. | |
| Pramipexole Formaldehyde Adduct Impurity | An metabolitic impurity of Pramipexole which is a thiazole derivative usually used as a D2-receptor agonist. Grades: > 95%. Molecular formula: C11H17N3S. Mole weight: 223.34. | |
| Pramipexole Impurity 10 | Pramipexole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 675112-40-0. Molecular Formula: C6H12ClNO. Mole Weight: 149.62. Catalog: APB675112400. | |
| Pramipexole Impurity 10 HCl | Pramipexole Impurity 10 HCl. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6S,7S)-2-amino-6-(propylamino)-4,5,6,7-tetrahydrobenzo[d]thiazol-7-ol. CAS No. 1798014-87-5. Molecular Formula: C10H17N3OS. Mole Weight: 227.33. Catalog: APB1798014875. | |
| Pramipexole Impurity 10 hydrochloride | An impurity of Pramipexole which is a thiazole derivative usually used as a D2-receptor agonist. Synonyms: 4-aminocyclohexanone hydrochloride. CAS No. 675112-40-0. Molecular formula: C6H12NOCl. Mole weight: 149.62. | |
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