A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Acts as liquid surfactant, wetting agent, emulsifier, solubilizer, conditioner and coupling agent. Used in conditioners and other cosmetic care products. Saponification value 2 maximum. Uses: Emulsions for skin and hair care products. Group: Surfactants/emulsifiers. CAS No. 25231-21-4. Appearance: Clear colorless oily liquid, faint characteristic fatty odor. Catalog: CI-SC-0240.
PPG-12 PEG-50 Lanolin
Alkoxylated water-soluble lanolin derivative. It is an excellent emulsifier and is suitable for use in hair care, after-shave products, antiperspirants and suncare. As well as emulsification, it also acts as a solubilizer and plasticizer. Uses: Skin and hair care products, color cosmetics. Group: Surfactants/emulsifiers. CAS No. 68458-88-8. Appearance: Liquid. Catalog: CI-SC-0295.
PPG-12/SMDI Copolymer
Copolymer of saturated methylene diphenyldiisocyanate and PPG-12 monomers. Skin conditioning, hair fixing, and film forming emollient. Uses: Skin and hair care products, color cosmetics. Group: Emollients/oils/wax. CAS No. 9042-82-4. Catalog: CI-SC-0384.
PPG-12/SMDI Copolymer
Copolymer of saturated methylene diphenyldiisocyanate and PPG-12 monomers. Skin conditioning, hair fixing, and film forming emollient. Uses: Skin and hair care products, color cosmetics. Group: Polymers. CAS No. 9042-82-4.
PPG-2 isoceteth-20 acetate
Heterocyclic Organic Compound. CAS No. 110332-91-7. Catalog: ACM110332917.
PPG-2 Myristyl Ether Propionate
Acts as liquid emollient, emulsifier and solvent. It has 86% bio-based content and renewable content. Used in bath, shower & soaps, shaving, body care, face color, facial cleansers, and deodorants. Saponification value 140-155. Uses: Emulsions for skin and hair care products, depilatories, antiperspirants. Group: Heterocyclic organic compound. CAS No. 74775-06-7. Appearance: Clear liquid. Catalog: ACM74775067.
PPG-3 Benzyl Ether Myristate
PPG-3 Benzyl Ether Myristate is a synthetic cosmetic ingredient that is often used as an emollient, or skin conditioner, in various personal care products. It is a water-soluble, clear, colorless to pale yellow, viscous liquid that is derived from myristic acid, a fatty acid found in coconut oil and other vegetable oils. PPG-3 Benzyl Ether Myristate is known for its ability to help reduce the appearance of fine lines and wrinkles by hydrating and softening the skin. It is commonly found in facial moisturizers, anti-aging creams, and other skin care products. It may also be used in hair care products, such as shampoos and conditioners, to help improve the texture and appearance of hair. Uses: 1. ppg-3 benzyl ether myristate is commonly used in personal care products as an emollient, which helps to soften and smooth the skin. 2. it is used in creams, lotions, and various skincare products as it has good spreading and lubricating properties. 3. due to its good skin penetration properties, it is also used in anti-aging formulations and sunscreens to enhance the efficacy of active ingredie. Group: Skin actives. CAS No. 642443-86-5. Appearance: clear, colorless liquid. Catalog: CI-SC-0731.
PPG-3 hydrogenated castor oil
Heterocyclic Organic Compound. CAS No. 111870-68-9. Catalog: ACM111870689.
ppg-3 methyl ether
Polypropylene glycol methyl ether is an odorless colorless liquid. Mixes with water. (USCG, 1999). Group: Polymers. CAS No. 37286-64-9. Product ID: 1-(1-methoxypropan-2-yloxy)propan-2-ol. Molecular formula: 148.2g/mol. Mole weight: C7H16O3. CC(COC(C)COC)O. InChI=1S/C7H16O3/c1-6 (8)4-10-7 (2)5-9-3/h6-8H, 4-5H2, 1-3H3. WGYZMNBUZFHYRX-UHFFFAOYSA-N.
PPG-PEG-PPG Blockcopolymer average Mn ~2,000
100g Pack Size. Group: Building Blocks, Organics, Peptide Reagents. CAS No. 9003-11-6. Prepack ID 90026319-100g. Molecular Weight average Mn ~2,000. See USA prepack pricing.
A toxic metabolite of Phenacetin which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils. Group: Biochemicals. Alternative Names: 4-Ethoxybenzenamine; 1-Amino-4-ethoxybenzene; 4-Aminophenetole; 4-Ethoxyaniline; 4-Ethoxybenzenamine; 4-Ethoxyphenylamine; NSC 3116; p-Aminophenetole; p-Ethoxyaniline; p-Ethoxyphenylamine; p-Phenetidin. Grades: Highly Purified. CAS No. 156-43-4. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
p-Phenetidine
P-phenetidine is a colorless to dark red liquid. (NTP, 1992);COLOURLESS LIQUID. TURNS DARK RED ON EXPOSURE TO AIR AND LIGHT. Group: Liquid crystal (lc) building blocks. CAS No. 156-43-4. Product ID: 4-ethoxyaniline. Molecular formula: 137.18g/mol. Mole weight: C8H11NO;C8H11NO. CCOC1=CC=C(C=C1)N. InChI=1S/C8H11NO/c1-2-10-8-5-3-7 (9)4-6-8/h3-6H, 2, 9H2, 1H3. IMPPGHMHELILKG-UHFFFAOYSA-N.
p-Phenetidine-d5 Hydrochloride
Labeled p-Phenetidine. A toxic metabolite of Phenacetin which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils. Group: Biochemicals. Alternative Names: 4-(Ethoxy-d5)benzenamine Hydrochloride; 1-Amino-4-(ethoxy-d5)benzene Hydrochloride; 4-Aminophenetole-d5 Hydrochloride; 4-Ethoxyaniline-d5 Hydrochloride; 4-(Ethoxy-d5)benzenamine Hydrochloride; 4-(Ethoxy-d5)phenylamine Hydrochloride; NSC 3116-d5 Hydrochloride; p-Aminophenetole-d5 Hydrochloride; p-Ethoxyaniline-d5 Hydrochloride; p-(Ethoxy-d5)phenylamine Hydrochloride; p-Phenetidin-d5 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
1kg Pack Size. Group: Amines, Analytical Reagents, Biochemicals, Building Blocks, Stains & Indicators. Formula: C6H4(NH2)2. CAS No. 106-50-3. Prepack ID 80820412-1kg. Molecular Weight 108.14. See USA prepack pricing.
p-Phenylenediamine
P-phenylenediamine appears as a white to purple crystalline solid (melting point 234 F) that turns purple to black in air. Flash point 309 F. Toxic by skin absorption, inhalation or ingestion. Used for production of aramid fiber, antioxidants, as a laboratory reagent, in photographic developing, and as a dye for hair and furs.;Liquid; PelletsLargeCrystals;WHITE-TO-SLIGHTLY-RED CRYSTALS. TURNS DARK ON EXPOSURE TO AIR.;White to slightly red, crystalline solid.;White to slightly red, crystalline solid. Group: Polymers. Product ID: benzene-1,4-diamine. Molecular formula: 108.14g/mol. Mole weight: C6H8N2;C6H4(NH2)2;C6H8N2. C1=CC(=CC=C1N)N. InChI=1S/C6H8N2/c7-5-1-2-6 (8)4-3-5/h1-4H, 7-8H2. CBCKQZAAMUWICA-UHFFFAOYSA-N.
p-Phenyloxyphenylacetic Acid
p-Phenyloxyphenylacetic Acid is an arylaliphatic acid used in the preperation of protential inhibitors of collagen-induced aggregation of human thrombocytes. p-Phenyloxyphenylacetic Acid is a predicted metabolite of 6-Amino-4- (4-phenoxyphenyl ethyl amino) quinazoline. Group: Biochemicals. Alternative Names: 4-Phenoxybenzeneacetic Acid; (4-Phenoxyphenyl)acetic Acid; 2-(4-Phenoxyphenyl)acetic Acid; 4- (Carboxymethyl) diphenyl Ether; 4-Phenoxyphenylethanoic Acid; NSC 43857; p-Phenyloxyphenylacetic Acid. Grades: Highly Purified. CAS No. 6328-74-1. Pack Sizes: 5mg. US Biological Life Sciences.
PPHT hydrochloride is a potent and selective dopamine D2 agonist. Uses: Dopamine agonists. Synonyms: (+/-)-PPHT hydrochloride; 6-[2-phenylethyl(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grades: 98%. CAS No. 71787-90-1. Molecular formula: C21H27NO.HCl. Mole weight: 345.91.
PPI-2458
PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class. Synonyms: PPI 2458; PPI2458; Metapro; NSC-720735. CAS No. 431077-35-9. Molecular formula: C22H36N2O6. Mole weight: 424.54.
PPI-2458
PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 ( MetAP-2 ). PPI-2458 can be used for arthritis and lymphoma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 431077-35-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13731.
PPIase-Parvulin Inhibitor
PPIase-Parvulin Inhibitor is a cell-permeable inhibitor of the PPIases Pin1 and Pin4 (IC50s = 1.5 and 1.0 μM, respectively). It blocks the proliferation of cancer cells that overexpress Pin1 and Pin4 (IC50 = 2-5 μM). Synonyms: HIC 016C; PiB; Diethyl-1, 3, 6, 8-tetrahydro-1, 3, 6, 8-tetraoxobenzo[lmn][3, 8]phenanthroline-2, 7-diacetate. Grades: ≥95%. CAS No. 64005-90-9. Molecular formula: C22H18N2O8. Mole weight: 438.4.
PPI Inhibitor Library
A unique collection of 260 PPI-related compounds for drug screening; - Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc. - Detailed compound information with structure, target, and biological activity description; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9400. Categories: PPI Inhibitor Libraries.
PPIP
Organic Light Emitting Diode (OLED). Alternative Names: 4,4'-Bis(1-phenyl-1H-phenanthro[9,10-d]imidazol-2-yl)biphenyl. CAS No. 1147081-46-6. Molecular formula: C54H34N4. Mole weight: 738.87. Catalog: ACM1147081466.
PPM-18
PPM-18 is a synthetic naphthoquinone compound and an anti-inflammatory agent. It potently inhibits the expression of inducible nitric oxide synthase (iNOS) via suppressing NF-κB activation in vitro and in vivo (IC50 = 5 μM). Synonyms: NSC 73233; n-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)benzamide; NQN-1; 2-Benzoylamino-1,4-naphthoquinone. Grades: ≥95%. CAS No. 65240-86-0. Molecular formula: C17H11NO3. Mole weight: 277.3.
PPM1A-IN-1
PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2919466-30-9. Pack Sizes: 1 mg. Product ID: HY-164220.
PPNDS
PPNDS is a potent and selective P2X1 receptor antagonist (pKB = 7.43 in rat vas deferens). PNDS is approximately 50-fold less selective for P2Y1R and does not interact with α1A-adrenergic, adenosine A1 and A2B, histamine H1, or muscarinic M3 receptors. Synonyms: Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt. CAS No. 1021868-77-8. Molecular formula: C18H11N4Na4O14PS2. Mole weight: 694.36.
PPNDS
PPNDS. Group: Biochemicals. Grades: Purified. CAS No. 1021868-77-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PPNDS tetrasodium
PPNDS tetrasodium is a selective and competitive meprin β inhibitor ( IC 50 : 80 nM, K i : 8 nM), and also inhibits ADAM10 ( IC 50 : 1.2 μM). PPNDS tetrasodium is also a P2X1 receptor antagonist. PPNDS is an agonist for the ATP receptor of Paramecium. PPNDS tetrasodium potently inhibits polymerases from viruses. PPNDS tetrasodium can be used in the research of infection and cancers [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021868-77-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108675.
PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. Synonyms: 6-(2-propargyloxyphenyl)hexanoic acid. Grades: ≥99%. CAS No. 206052-01-9. Molecular formula: C15H18O3. Mole weight: 246.3.
PPOH
PPOH, a fatty acid derivative, is a selective cyclooxygenase ( COX ) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC 50 values of 22 μM and 6.5 μM, respectively [1]. PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 206052-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119647.
PPPA is a competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors (Ki=0.13, 0.47, 1.10 and 3.86 μM for GluN2A, GluN2B, GluN2C and GluN2D subunits respectively). Some findings support the hypothesis that PPPA and reward synergize to enhance initiate dopamine (DA) excitation. Synonyms: (2R*,4S*)-4-(3-Phosphonopropyl)-2-piperidinecarboxylic acid. CAS No. 113190-92-4. Molecular formula: C9H18NO5P. Mole weight: 251.22.
PPPA
PPPA. Group: Biochemicals. Grades: Purified. CAS No. 113190-92-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PPP hydrochloride
PPP hydrochloride is a selective inactivator of human cytochrome P450 2B6 (CYP2B6). Synonyms: 1-(2-phenylpropan-2-yl)piperidine hydrochloride; 1-(alpha,alpha-Dimethylbenzyl)piperidine hydrochloride. Grades: 99%. CAS No. 21602-56-2. Molecular formula: C14H21N.HCl. Mole weight: 239.78.
PPQ 102. Group: Biochemicals. Grades: Purified. CAS No. 931706-15-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PPQ-102
PPQ-102 is a remarkable and highly specialized inhibitor, used in studying prostate cancer. Synonyms: PPQ-102; PPQ102; PPQ 102. CAS No. 931706-15-9. Molecular formula: C26H22N4O3. Mole weight: 438.487.
p-Propylacetophenone
Liquid, d20 0.98. CAS No. 2932-65-2. Pack Sizes: 25g. Product ID: FR-0376. B.P. 155-158/18 mm. Mole weight: 162.23.
Frinton Laboratories
Pps I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 20% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 25U; 125U. GAGTC(N)4↑ CTCAG(N)5&darr. Activity: 500-1000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Pseudomonas pseudoalcaligenes. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA and 50% glycerol. Cat No: ET-1149RE.
PPT
PPT, also known as Propyl pyrazole triol, is an ERα selective agonist with a 410-fold relative binding affinity for ERα (49%) versus ERβ (0.12%) and therefore activates gene transcription only through ER&alpha. PPT significantly decreased infarct size in an in vivo rabbit model of ischemia-reperfusion injury. PPT also exerts anti-diabetic effects in mouse models. Synonyms: 4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol; Propyl pyrazole triol. Grades: ≥99% by HPLC. CAS No. 263717-53-9. Molecular formula: C24H22N2O3. Mole weight: 386.45.
PPT
PPT. Group: Biochemicals. Grades: Purified. CAS No. 263717-53-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PPTN
PPTN is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160271-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-110322A.
PPTN hydrochloride
PPTN, a 4,7-disubstituted 2-naphthoic acid derivative, is a high affinity and selective P2Y14 antagonist (KB = 434 pM) with >10,000-fold selectivity for P2Y14 over other P2Y receptors. PPTN blocks UDP-glucose-promoted chemotaxis of human neutrophils and does so across a concentration range consistent with its KB determined in the P2Y14-R-expressing cell line. Synonyms: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1992047-65-0. Molecular formula: C29H24F3NO2.HCl. Mole weight: 511.96.
PPTN hydrochloride
PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110322.
PPY A
PPY A. Group: Biochemicals. Grades: Purified. CAS No. 875634-01-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PPY A
PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinases (IC50= 9 and 20 nM, respectively) that inhibits growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene. Synonyms: 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide. Grades: ≥98% by HPLC. CAS No. 875634-01-8. Molecular formula: C22H20N4O2. Mole weight: 372.42.
PPZ2
PPZ2 is a diacylglycerol (DAG)-activated TRPC3/TRPC6/TRPC7 channel activator with activity in promoting neuronal development and survival. PPZ2 activates recombinant TRPC3/TRPC6/TRPC7 channels in a dose-dependent manner without affecting other TRPC channels. PPZ2 elicits cation currents and calcium ion (Ca(2+)) influx in cultured central neurons. PPZ2 is able to induce BDNF-like neurite outgrowth and neuroprotection, an effect that disappears after TRPC3/TRPC6/TRPC7 knockdown or inhibition. PPZ2 also increases the activation of the calcium-dependent transcription factor cAMP response element binding protein. The effects of PPZ2 suggest that calcium signaling mediated by activation of DAG-activated TRPC channels plays an important role in its neurotrophic effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896203-18-2. Pack Sizes: 5 mg. Product ID: HY-111527.
PQ-10
PQ-10 is a potent and selective inhibitor of phosphodiesterase type 10 (PDE10). Synonyms: 6,7-dimethoxy-4-[(3R)-3-(quinoxalin-2-yloxy)pyrrolidin-1-yl]quinazoline. Grades: ≥98%. CAS No. 927691-21-2. Molecular formula: C22H21N5O3. Mole weight: 403.4.
PQ-10
PQ-10 is a potent inhibitor of Phosphodiesterase 10A ( PDE10A ) with IC 50 and ED 50 of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 927691-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18078.
PQ 401
PQ 401 is an IGF-1R inhibitor and inhibits autophosphorylation of the IGF-IR kinase domain at concentrations <100 nM, with an IC50 <1μM. Synonyms: PQ401; PQ-401; PQ 401. Grades:>98%. CAS No. 196868-63-0. Molecular formula: C18H16ClN3O2. Mole weight: 341.79.
PQ 401
PQ 401. Group: Biochemicals. Grades: Purified. CAS No. 196868-63-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PQ 69
PQ 69 is a potent and selective A1 receptor inverse agonist, with high binding affinity at A1 receptor (Ki= 0.07 and 0.96 nM for rat and human receptors respectively). It exhibits 217-fold more selective compared with hA2A receptors and >1,000-fold selectivity for hA1 over hA3 receptor. PQ-69 exhibits potent antagonist effects on A1AR in vitro, ex vivo and in vivo. Synonyms: 4-(Butylamino)-2-(3-fluorophenyl)-1,2-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one; PQ-69; PQ 69; PQ69. Grades: ≥98% by HPLC. CAS No. 910045-32-8. Molecular formula: C20H19FN4O. Mole weight: 350.39.
PQCA is a highly selective and potent muscarinic M1 receptor positive allosteric modulator. PQCA has an EC 50 value of 49 nM and 135 nM on rhesus and human M1 receptor , respectively. PQCA is inactive for other muscarinic receptors. PQCA has potential to reduce the cognitive deficits associated with Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1144504-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118342.
PQCA
This active molecular is a muscarinic M1 receptor positive allosteric modulator which is able to improve cognitive measures in rat and rhesus monkeys. PQCA is very efficient in rodent and nonhuman primate (NHP) cognition assays and it can improve performance on translatable tests of Memory and Attention in rhesus monkeys. PQCA attenuates learning and memory deficits in Alzheimer's disease model. PQCA may be potential useful in treating Alzheimer's diseases in the future. Uses: Treatment of alzheimer's diseases. Synonyms: 1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid,1401512-98-8 (sodium). Grades: 98%. CAS No. 1144504-35-7. Molecular formula: C22H20N4O3. Mole weight: 388.43.
PQQ DISODIUM SALT
PQQ DISODIUM SALT, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. CAS No. 122628-50-6. Product ID: CDF4-0242. Molecular formula: C14H4N2Na2O8. Category: Nutrients. Product Keywords: Nutrients; PQQ DISODIUM SALT; CDF4-0242; Nutrients; C14H4N2Na2O8; 122628-50-6. EC Number: 209-118-9. Storage: 2-8°C. Applications: Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function. Product Description: Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function.
PQR309
PQR309, a pan inhibitor of phosphoinositide-3-kinases, is still under Phase II clinical trial against Glioblastoma and Lymphoma. Uses: Pqr309 is a pan inhibitor of phosphoinositide-3-kinases and is still under phase ii clinical trial against glioblastoma and lymphoma. Synonyms: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine; PQR309; PQR-309; PQR309; Bimiralisib free base. Grades: 98%. CAS No. 1225037-39-7. Molecular formula: C17H20F3N7O2. Mole weight: 411.38.
PQR530
PQR530 is a potent dual pan PI3K/mTOR inhibitor undergoing phase II clinical trials in 2016. Aberrant activation of the PI3K/mTOR signaling pathway promotes the growth of malignant tumor cells. Study showed that PQR530 inhibited all PI3K isoforms and the mammalian target of rapamycin (mTOR) complexes C1/2 potently and selectively against tumor progression. Synonyms: PQR530; PQR0530; PQR 530. (S)-4-(difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine. Grades: ≥98%. CAS No. 1927857-61-1. Molecular formula: C18H23F2N7O2. Mole weight: 407.42.
PqsR/LasR-IN-3
PqsR/LasR-IN-3 (Compound 7a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-3 also inhibits hERG with the IC 50 of 109.01 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2581109-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146329.
PQT-12
Band gap: 2.27 eV. Uses: Pqt-12 is a solution processable p-type, π-conjugated semiconductor for felxible printed electronics such as high sensitivity chemical sensors based on organic thin film transistors. it can also be used as donor material in organic solar cells.researches show that the microstructure of pqt-12 can be controled by the choice of solvent.study has shown pqt-12 spin-coated on a donor substrate can b. Group: Flexible printed electronics. Alternative Names: Poly(3, 3'''-didodecyl[2, 2':5', 2'':5'', 2'''-quaterthiophene]-5, 5'''-diyl), Poly(4, 4''-didodecyl[2, 2':5', 2'':5'', 2'''-quaterthiophene]-5, 5'''-diyl). CAS No. 827343-06-6. Molecular formula: (C40H56S4)n. Catalog: ACM827343066.
PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 has a high potency (Ki = 89 nM) and selectivity. Its oral bioavailability in the mouse is 17% as well as half-life is 3.4 h after oral dosing. Uses: The treatment of inflammatory bowel disease (ibd). Synonyms: PR-073; PR 073; PR073.