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Product
PD166793 hydrate ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PD 166866 PD 166866. Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) . Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H24N6O3. US Biological Life Sciences. USBiological 8
Worldwide
PD-166866 A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF). Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) . Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
PD-166866 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopypharmaceutical toxicology. Alfa Chemistry Analytical Products
PD-166866 PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC 50 of 52.4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 192705-79-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101296. MedChemExpress MCE
PD 168077 maleate PD 168077 maleate. Group: Biochemicals. Grades: Purified. CAS No. 630117-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PD-168077 maleate PD-168077 maleate is a selective dopamine D 4 receptor agonist, with a K i of 9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 630117-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-21098A. MedChemExpress MCE
PD 168077 Maleate (D4 Dopamine Receptor Agonist, PD 168077 Maleate, PD168077, PD-168077) A selective D4 dopamine receptor agonist (Ki = 8.7nM, EC50 = 8.3nM). Suitable for central and peripheral delivery. Used in studies of penile erection, learning and memory. Exibits some binding affinity towards human D2 and D3 Receptors (Ki = 2.8uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 630117-19-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
PD 168,077 maleate salt powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD168393 PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 194423-15-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13896. MedChemExpress MCE
PD168393 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
PD 168393 PD 168393. Group: Biochemicals. Alternative Names: N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide. Grades: Highly Purified. CAS No. 194423-15-9. Pack Sizes: 1mg. Molecular Formula: C17H13BrN4O, Molecular Weight: 369.22. US Biological Life Sciences. USBiological 3
Worldwide
PD 168393 - CAS 194423-15-9 A potent, cell-permeable, irreversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC?? = 700 pM). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
PD 168568 dihydrochloride PD 168568 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 210688-56-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PD 169316 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
PD 169316 PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM. PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71. PD169316 shows antiviral activity against Enterovirus71. Uses: Scientific research. Group: Signaling pathways. CAS No. 152121-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10578. MedChemExpress MCE
PD 169316 - CAS 152121-53-4 A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC?? = 89 nM). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
PD173074 PD173074 is a potent FGFR1 inhibitor with an IC50 of 25 nM and also inhibits VEGFR2 with an IC50 of 100-200 nM, showing 1000-fold selectivity for FGFR1 over PDGFR and c-Src. Uses: Scientific research. Group: Signaling pathways. CAS No. 219580-11-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10321. MedChemExpress MCE
PD 173074 ?96% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD-173074 PD 173074. Group: Biochemicals. Alternative Names: N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; PD 173074. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
PD-173074-d9 Labeled PD 173074. Group: Biochemicals. Alternative Names: N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl-d9) urea. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
PD-173074-[d9] Labelled PD 173074, a selective FGFR1 and FGFR3 inhibitor. The compound induced a dose-dependent reduce in cell viability and an increase in apoptosis, accompanied by a decrease in extracellular signal-related kinase phosphorylation. Synonyms: PD-173074 D9; N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl-d9)urea. CAS No. 1794979-29-5. Molecular formula: C28H32D9N7O3. Mole weight: 532.73. BOC Sciences 2
PD 173074 (N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N’- (1, 1-dimethylethyl) urea A potent and selective FGFR1 tyrosine kinase inhibitor (IC50 = 21.5nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential. Group: Biochemicals. Alternative Names: PD173074, N-[2-[[4- (Diethylamino) butyl]amino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N’- (1, 1-dimethylethyl) urea. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 2mg. US Biological Life Sciences. USBiological 1
Worldwide
PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor) PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor). Group: Biochemicals. Alternative Names: 1-tert-butyl-3-[2-[4- (diethylamino) butylamino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 25mg. Molecular Formula: C28 H41 N7O3 , Molecular Weight: 523.7. US Biological Life Sciences. USBiological 9
Worldwide
PD 173212 PD 173212. Group: Biochemicals. Grades: Purified. CAS No. 217171-01-2. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
PD173952 PD173952 is a tyrosine kinases inhibitor with IC50s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk, respectively. PD173952 is also a potent Myt1 kinase inhibitor with a Ki of 8.1 nM. PD173952 induces apoptosis[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305820-75-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122113. MedChemExpress MCE
PD173952 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD 173952 PD 173952. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -8-methyl-2-[[4- (4-morpholinyl) phenyl]amino]pyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 305820-75-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H21Cl2N5O2. US Biological Life Sciences. USBiological 8
Worldwide
PD-173952 A Bcr-Abl tyrosine kinase inhibitor used in treatment research for chronic myelegenous leukemia (CML). Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -8-methyl-2-[[4- (4-morpholinyl) phenyl]amino]pyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 305820-75-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
PD173955 PD173955 is an orally active inhibitor of Src (IC50= 22 nM), Yes, Abl, ATP and MAP kinases. PD173955 can effectively prevent the mitotic process and has anticancer activity[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 260415-63-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10395. MedChemExpress MCE
PD-173955 PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PD173955; PD 173955; PD173955. Product Category: Inhibitors. Appearance: White solid powder. CAS No. 260415-63-2. Molecular formula: C21H16Cl2N4OS. Mole weight: 443.35. Purity: >98%. IUPACName: 6-(2,6-dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. Canonical SMILES: O=C1C(C2=C(Cl)C=CC=C2Cl)=CC3=CN=C(NC4=CC=CC(SC)=C4)N=C3N1C. Product ID: ACM260415632. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Pd 174265 Pd 174265. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PD 174265;4-[(3-BROMOPHENYL)AMINO]-6-PROPIONYLAMIDOQUINAZOLINE. Product Category: Heterocyclic Organic Compound. Appearance: Yellow solid. CAS No. 216163-53-0. Molecular formula: C17H15BrN4O. Mole weight: 371.23. Purity: ≥97%. Product ID: ACM216163530. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
PD 174265 PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR with an IC 50 of 450 pM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216163-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112411. MedChemExpress MCE
PD 174265 - CAS 216163-53-0 A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC?? = 450 pM). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD176252 PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 ?M in HL-60 cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 204067-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103286. MedChemExpress MCE
PD 176252 PD 176252. CAS No: 204067-01-6 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
PD 176252 PD 176252. Group: Biochemicals. Grades: Purified. CAS No. 204067-01-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
PD180970 PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8 nM and 50 nM, respectively. PD180970 indcues apoptosis of K562 leukemic cells, and can be used for chronic myelogenous leukemia research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 287204-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-103274. MedChemExpress MCE
PD-180970 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD 184161 PD 184161. Group: Biochemicals. Alternative Names: 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Grades: Highly Purified. CAS No. 212631-67-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H13BrClF2IN2O2. US Biological Life Sciences. USBiological 8
Worldwide
PD-184161 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD184352 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
PD 184352 PD 184352. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; 3, 4-Difluoro-2- (2-chloro-4-iodophenylamino) -N-cyclopropyl methoxybenzamide; CI 1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H14ClF2IN2O2. US Biological Life Sciences. USBiological 8
Worldwide
PD-184352 An inhibitor of ERK signaling pathway. A MAP kinase inhibitor. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; 3, 4-Difluoro-2- (2-chloro-4-iodophenylamino) -N-cyclopropyl methoxybenzamide; CI 1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040) MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer. Group: Biochemicals. Alternative Names: 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H14ClF2IN2O2, Molecular Weight: 478.7. US Biological Life Sciences. USBiological 3
Worldwide
PD184352 (Cl-1040, 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide) PD184352 is an inhibitor of mitogen activated protein kinase kinase (MEK or MAPKK). Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
Worldwide
PD 198306 PD 198306. Group: Biochemicals. Grades: Purified. CAS No. 212631-61-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
PD-1/PD-L1-IN-14 PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions, with an IC50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2499965-12-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144258. MedChemExpress MCE
PD-1/PD-L1-IN-23 PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester proagent of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2597056-04-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145774. MedChemExpress MCE
PD-1/PD-L1 Inhibitor 3 PD-1/PD-L1 Inhibitor 3 is a PD-1/PD-L1 interaction inhibitor with IC50 value of 5.6 nM. Synonyms: Programmed Death-1/Programmed Death-Ligand 1 Inhibitor 3. Grade: ≥97% by HPLC. CAS No. 1629654-95-0. Molecular formula: C89H126N24O18S. Mole weight: 1852.2. BOC Sciences
PD 224378 PD 224378. Group: Biochemicals. Alternative Names: (4R)-1-(4-O- β-D-Galactopyranosyl- β-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone. Grades: Highly Purified. CAS No. 501665-88-9. Pack Sizes: 1mg. Molecular Formula: C20H35NO11, Molecular Weight: 465.49. US Biological Life Sciences. USBiological 3
Worldwide
Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)) Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)). CAS No: 51364-51-3 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
PD 312236, PD 312237 Mixture PD 312236 is a pyranoside lactose conjugate degradation product of pregabalin, a GABA analogue used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-Deoxy-4-O- β-D-galactopyranosyl-1-[(4S)-4-(2-methylpropyl)-2-oxo-1-pyrrolidinyl]- β-D-fructose, Pyranose / Furanose Mixture. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C??H??NO??, Molecular Weight: 465.49. US Biological Life Sciences. USBiological 3
Worldwide
PD 312237 PD 312237. Group: Biochemicals. Alternative Names: 1-Deoxy-4-O- β-D-galactopyranosyl-1-[(4R)-4-(2-methylpropyl)-2-oxo-1-pyrrolidinyl]- β-D-fructofuranose. Grades: Highly Purified. CAS No. 501666-23-5. Pack Sizes: 1mg. Molecular Formula: C20H35NO11, Molecular Weight: 465.49. US Biological Life Sciences. USBiological 3
Worldwide
PD318088 PD318088. Uses: Designed for use in research and industrial production. Product Category: Bromine Series. CAS No. 391210-00-7. Product ID: ACM391210007. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
PD318088 PD318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD184352 (HY-50295). PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. PD318088 can be used for cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 391210-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12062. MedChemExpress MCE
PD-325901 3-Carboxylic Acid PD-325901 3-Carboxylic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C16H12F3IN2O5, Molecular Weight: 496.18. US Biological Life Sciences. USBiological 3
Worldwide
PD-325901-d3 3-Caboxylic Acid PD-325901-d3 3-Caboxylic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C16H9D3F3IN2O5, Molecular Weight: 499.2. US Biological Life Sciences. USBiological 3
Worldwide
PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III) A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC50 = 0.33nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells. PD 325901 is an inhibitor of mitogen activated protein kinase kinase (MEK or MAPKK). The potency, solubility and effectiveness of PD 325901 are greatly improved compared to PD 184352 (CI-1040). Group: Biochemicals. Alternative Names: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2[(2-fluoro-4-iodophenyl)amino]-benzamide; PD 0325901, MEK1/2 Inhibitor III. Grades: Highly Purified. CAS No. 391210-10-9. Pack Sizes: 10mg, 25mg. US Biological Life Sciences. USBiological 1
Worldwide
PD 334581 PD 334581. Group: Biochemicals. Grades: Purified. CAS No. 548756-68-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PD 404182 PD 404182. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,4-Dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Appearance: Solid. CAS No. 72596-74-8. Molecular formula: C11H11N3S. Mole weight: 217.29. IUPACName: 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Canonical SMILES: C1CN=C2C3=CC=CC=C3SC(=N)N2C1. Product ID: ACM72596748-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
PD 407824 PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC50s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 622864-54-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18961. MedChemExpress MCE
PD-407824 PD-407824 is a Wee1/Chk1 inhibitor useful as cancer treatments. Group: Biochemicals. Alternative Names: 9-Hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione; PD 0407824. Grades: Highly Purified. CAS No. 622864-54-4. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
PD-407824 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
PD 81723 PD 81723. Group: Biochemicals. Grades: Purified. CAS No. 132861-87-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PD 90780 PD 90780. Group: Biochemicals. Grades: Purified. CAS No. 77422-99-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PD98059 PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 μM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 μM) and MEK2 (IC50 of 50 μM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 ?M) and AHR transformation (IC50 of 1 ?M). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 167869-21-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12028. MedChemExpress MCE
PD 98059 PD 98059. Group: Biochemicals. Grades: Purified. CAS No. 167869-21-8. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PD 98,059 solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
PD 98,059 Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells. Group: Biochemicals. Alternative Names: 2- (2-Amino-3-methoxyphenyl) -4H-1-benzopyran-4-one; 2- (2’-amino-3’-methoxyphenyl) oxanaphthalen-4-one; NSC 679828; PD 098059. Grades: Highly Purified. CAS No. 167869-21-8. Pack Sizes: 1mg, 5mg, 10mg, 50mg. Molecular Formula: C??H??NO?, Molecular Weight: 267.3. US Biological Life Sciences. USBiological 3
Worldwide

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