A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| PD 98059 - CAS 167869-21-8 | PD 98059, CAS 167869-21-8, is a cell-permeable, selective & reversible inhibitor of MAP Kinase Kinase (MEK). Inhibits MAP Kinase activation and subsequent phosphorylation of MAP Kinase substrates. Group: Fluorescence/luminescence spectroscopy. |  |
| PDAT | PDAT is a noncompetitive indolethylamine-N-methyltransferase (INMT) inhibitor with a K i of 84 μM for rabbit lung INMT (rabINMT) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226213-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124101. |  |
| pdBD-2 | pdBD-2 is an antimicrobial peptide found in Chinese loach, Paramisgurnus dabryanus. It has anti-gram-positive bacteria and gram-negative bacteria activity. Synonyms: Paramisgurnus dabryanus beta defensin 2. Grade: >98%. |  |
| PDBT-co-TT | PDBT-co-TT. Uses: Designed for use in research and industrial production. Product Category: Flexible Printed Electronics. CAS No. 1260685-65-1. Product ID: ACM1260685651. Alfa Chemistry ISO 9001:2015 Certified. |  |
| PDBT-T1 | Band gap: 1.93 eV. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: Poly[[5,10-bis(5-octyl-2-thienyl)dithieno[2,3-d:2',3'-d']benzo[1,2-b:4,5-b']dithiophene-2,7-diyl]-2,5-thiophenediyl[5,7-bis(2-ethylhexyl)-4,8-dioxo-4H,8H-benzo[1,2-c:4,5-c']dithiophene-1,3-diyl]-2,5-thiophenediyl]. CAS No. 1701403-91-9. Mole weight: (C72H78O2S10)n. |  |
| PDCD4-IN-1 | PDCD4-IN-1(compound 20031600) is a PDCD4 inhibitor with a K d value of 350 nM, which can promote the expression of BDNF in hippocampal neuron cell HT-22 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 494763-64-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153383. | |
| PDCDT | PDCDT. Group: Organic field effect transistor (ofet) materials. Alternative Names: N N-BIS(2 5-DI-T-BU-PHENYL)-3 4 9 10-; N,N-bis(2,5-di-T-bu-phenyl)-3,4,9,10-perylenedic; N,N-bis(2,5-di-T-butylphenyl)-3,4*9,10-perylened; N,N-BIS(2,5-DI-T-BU-PHENYL)-3,4,9,10-PE RYLENEDICARBOXIMIDE; 2,9-BIS(2,5-BIS(1,1-DIMETHYLETHYL)PHENYL)-ANTRA(2,19-DEF:6. CAS No. 83054-80-2. Product ID: 7, 18-bis(2, 5-ditert-butylphenyl)-7, 18-diazaheptacyclo[14.6.2.22, 5.03, 12.04, 9.013, 23.020, 24]hexacosa-1(23), 2, 4, 9, 11, 13, 15, 20(24), 21, 25-decaene-6, 8, 17, 19-tetrone. Molecular formula: 767g/mol. Mole weight: C52H50N2O4. CC (C) (C)C1=CC (=C (C=C1)C (C) (C)C)N2C (=O)C3=C4C (=CC=C5C4=C (C=C3)C6=C7C5=CC=C8C7=C (C=C6)C (=O)N (C8=O)C9=C (C=CC (=C9)C (C) (C)C)C (C) (C)C)C2=O. InChI=1S/C52H50N2O4/c1-49 (2, 3)27-13-23-37 (51 (7, 8)9)39 (25-27)53-45 (55)33-19-15-29-31-17-21-35-44-36 (22-18-32 (42 (31)44)30-16-20-34 (46 (53)56)43 (33)41 (29)30)48 (58)54 (47 (35)57)40-26-28 (50 (4, 5)6)14-24-38 (40)52 (10, 11)12/h13-26H, 1-12H3. BIYPCKKQAHLMHG-UHFFFAOYSA-N. | |
| PdCl2(Amphos)2 | PdCl2(Amphos)2 is a catalyst that is more suitable for use in water than organic solvents [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 887919-35-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W010686. | |
| PDD00017272 | PDD00017272 is an inhibitor of poly(ADP-ribose) glycohydrolase (PARG) (EC50=4.8 nM) and an activator of PARP1/2. PDD00017272 inhibits its activity of hydrolyzing poly(ADP-ribose) (pADPr), resulting in the accumulation of pADPr on chromatin, interfering with DNA damage repair and replication processes, and inducing PARP1/2-dependent cytotoxicity. PDD00017272 can be used in cancer models with DNA repair defects (such as BRCA mutations) or resistance to PARP inhibitors. PDD00017272 has a PARG expression level-correlated inhibitory potency with EC50 of 9.2 nM (PARG cells), the tumor cells with lower PARG expression are more sensitive[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1945950-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133531. | |
| PDD00017273 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PDD 00017273 | PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1945950-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-108360. | |
| PDDC | PDDC is a compound used to inhibit Alzheimer's disease. It is a nSMase2 inhibitor that can inhibit tau-induced nSMase2 activity and ceramide elevation, and slow the spread of tau in mouse models. Uses: Scientific research. Group: Signaling pathways. CAS No. 2232878-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156800. | |
| PDE10A1 Active human | recombinant, expressed in baculovirus infected insect cells, ?60% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE10A Active from mouse | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE10A Active from rat | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE10A Inhibitor, Cpd15 (Phosphodiesterase 10A Inhibitor, (6-chloro-3,8-dimethyl-1H-pyrazolo[3,4-b]quinolin-4-yl)(2-methylpyrimidin-5-yl)methanol) | A cell-permeable pyrazoloquinoline compound that acts as a potent phosphodiesterase 10A inhibitor (Ki≤5nM against human PDE10A), while exhibiting >500-fold selectivity over other human PDEs 1-11 and little activity against CYP3A4 (IC50 >20uM) or a panel of 23 kinases (IC50 >30uM). Reported to be orally available in monkey and rat species and be efficacious in reversing nMDAR antagonist (+)-MK-801-induced hyperactivity in a ratsl (MED = 10mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences. |  Worldwide |
| PDE11A4 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE1A, active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDE1A Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE1B active from Rat, Recombinant | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene. Rat pde1b (genbank accession no. nm_022710) full length with n-terminal his-gst-tag, mw=89kda, expressed in a baculovirus infected sf9 cell expression system. Group: Enzymes. Synonyms: PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Purity: > 70% (SDS-PAGE). PDE. Mole weight: mol wt 89 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Cat No: NATE-0517. |  |
| PDE1B Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE1B active rat | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE1C Active from mouse | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE1C, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDE2A Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE2A active rat | recombinant, expressed in baculovirus infected Sf9 cells, ?56% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE2A FLAG tag active human | recombinant, expressed in baculovirus infected Sf9 cells, ?88% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4A10 active from Human, Recombinant | Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW=117 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Uman pde4a10, also known as pde4a protein isoform 6, transcript variant 3 (genbank accession no. nm_001111309) amino acids 2-825 (end) with n-terminal gst-tag, mw=117 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 75% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 117 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0523. | |
| PDE4A10 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4A1A Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4A4B active from Human, Recombinant | Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307) amino acids 2-end with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4a4b, also known as pde4a isoform 1 (genbank accession no. nm_001111307) amino acids 2-end with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 40% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0524. | |
| PDE4A4B active human | recombinant, expressed in baculovirus infected Sf9 cells, ?40% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4B1 Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4B2 Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4B (305-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDE4C1 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4C Active from mouse | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4D2 active from Human, Recombinant | Human PDE4D2 (GenBank Accession No. NM_001197221) amino acids 2-507 (end) with N-terminal GST-tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d2 (genbank accession no. nm_001197221) amino acids 2-507 (end) with n-terminal gst-tag, mw=84 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 80% (SDS-PAGE). PDE. Mole weight: mol wt 84 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0525. | |
| PDE4D2 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4D3 Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4D7 active from Human, Recombinant | Human PDE4D7 (GenBank Accession No. NM_001165899) amino acids 2-748 (end) with N-terminal GST-tag, MW=111 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d7 (genbank accession no. nm_001165899) amino acids 2-748 (end) with n-terminal gst-tag, mw=111 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 111 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0526. | |
| PDE4D7 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?65% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE4D Inhibitor, GEBR-7b ((E)-3-(cyclopentyloxy)-4-methoxybenzaldehyde, O-2-(2,6-dimethylmorpholino)-2-oxoethyl oxime, GEBR-7b) | A cell permeable, potent, and selective oxime PDE4D inhibitor (IC50=0.67uM) which displays much reduced activities toward other PDE4 isoforms. It is shown to cause a significant 40% increase in extracellular cAMP in the hippocampus of freely moving rats in vivo at 100uM, but has no effect on Ab levels. This compound elicits cognitive enhancement in vivo at the optimum dose of 0.003mg/kg in both mice and rat models, and unlike rolipram, does not cause emesis-like behavior in rodents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PDE5A1 active from Mouse, Recombinant | Mouse PDE5A (GenBank Accession No. NM_153422) full length with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Mouse pde5a (genbank accession no. nm_153422) full length with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Purity: > 70% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Cat No: NATE-0528. | |
| PDE5A1 active murine | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE6A (31-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDE6B, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDE7A Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE7A active mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?22% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE7A active rat | recombinant, expressed in baculovirus infected Sf9 cells, ?30% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE7B active from Mouse, Recombinant | Mouse PDE7B (GenBank Accession No. NM_013875) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Mouse pde7b (genbank accession no. nm_013875) amino acids 108-446 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Cat No: NATE-0531. | |
| PDE7B active from Rat, Recombinant | Rat PDE7B (GenBank Accession No. NM_080894) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Rat pde7b (genbank accession no. nm_080894) amino acids 108-446 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Purity: > 30% (SDS-PAGE). PDE. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Cat No: NATE-0532. | |
| PDE7B Active human | recombinant, expressed in baculovirus infected insect cells, ?40% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE7B active mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?65% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE7B active rat | recombinant, expressed in baculovirus infected Sf9 cells, ?30% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE8A1 Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE9A2 Active human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDE-9 inhibitor | PDE-9 inhibitor is useful for neurodegenerative diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1082743-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-50865. | |
| PDE9-IN-(S)-C33 | PDE9-IN-(S)-C33 is a potent and selective inhibitor of phosphodiesterase-9 (PDE9). Uses: Designed for use in research and industrial production. Additional or Alternative Names: PDE9-IN-(S)-C33; PDE9IN(S)C33; PDE9 IN (S) C33; (S)-C33. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2066488-39-7. Molecular formula: C18H20ClN5O. Mole weight: 357.84. Purity: >98%. IUPACName: 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one. Canonical SMILES: O=C1C2=C(N(C3CCCC3)N=C2)N=C(N[C@H](C4=CC=C(Cl)C=C4)C)N1. Product ID: ACM2066488397. Alfa Chemistry ISO 9001:2015 Certified. | |
| p-Decyloxyaniline | Off-white powder, 99%. CAS No. 39905-47-0. Pack Sizes: 5g, 25g. Product ID: FR-1212. M.P. 48-50, B.P. 184-188/1 mm. Mole weight: 249.4. |  Frinton Laboratories |
| p-Decyloxybenzylidene p-Toluidine | 10O.1, liquid crystal. CAS No. 53764-62-8. Pack Sizes: 2g. Product ID: FR-1201. M.P. 65 (S), 75 (N), 79 (I). Mole weight: 351.53. | Frinton Laboratories |
| PDGF-AA from mouse | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| PDGF-BB from mouse | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| PDGF-BB human | Animal-component free, recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| PDGF-CC human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFR? (550-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFR?(557-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFR-?, active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| PDGFRb active human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| PDGFRb/RAF Kinase Inhibitor | An orally bioavailable amino-triazole compound that is shown to bind to the inactive conformations of both PDGFRb and Raf kinases (allosteric, Type II inh), and acts as a potent inhibitor of Flt3, Kit, PDGFRa and PDGFRb (=52, 170, 300 and 520nM, respectively) with selectivity over B-Raf, p38a, FGFR2 and VEGFR2 (>10uM) in a multi-kinase panel. Completely blocks the phosphorylations of MEK-1/2 S217/S221, ERK-1/2 T202/Y204 in FGF-stimulated HUVECs, PDGFRb in PDGF-BB-stimulated VSMCs, ERK-1/2 T202/Y204 in 1205Lu-B Raf V600E cells, and C-Raf S338 at 10uM. Reduces FGF-induced angiogenesis in mouse Matrigel model (50mg/kg, i.p., bid) and selectively induces apoptosis in the endothelium; further, suppresses orthotopic renal cell carcinoma growth in mice (100mg/kg, p.o., qd). Group: Biochemicals. Alternative Names: 6- (4- (5- (3- (Trifluoromethyl) phenylamino) -4 H-1,2,4-triazol-3-yl)phenoxy)-2-(methylthio)pyrimidin-4-amine, PDGFR Tyrosine Kinase Inhibitor XXII. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?OS, Molecular Weight: 459.6. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
