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| Product | Description | |
|---|---|---|
| PC Spacer Phosphoramidite | PC Spacer phosphoramidite can be used as an intermediate to link any modification reagent (which can be used as phosphoramidite) to the end of the oligonucleotide. After light cleavage, 5'-phosphate is generated on the DNA, making it suitable for further biotransformation, such as gene construction and cloning after ligation. Synonyms: [4-(4,4'-Dimethoxytrityloxy)butyramidomethyl)-1-(2-nitrophenyl)-ethyl]-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C43H53N4O8P. Mole weight: 784.88. |  |
| PCTFE Products | PCTFE Products. Group: Polymers. |  |
| Pct I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme >90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GAATGCN↑ CTTAC↓GN. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Planococcus citreus SM. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; and 50% glycerol. Cat No: ET-1147RE. |  |
| PCy3 Pd G2 | PCy3 Pd G2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (SP-4-3)-[2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC]chloro(tricyclohexylphosphine)palladium. Product Category: Organic Phosphine Compounds. Appearance: Light pink powder. CAS No. 1353658-81-7. Molecular formula: C30H43ClNPPd. Mole weight: 590.52. Purity: 0.98. Product ID: ACM1353658817. Alfa Chemistry ISO 9001:2015 Certified. |  |
| p-Cyanoacetophenone | Used in the preparation of antimalarial isonitriles. Group: Biochemicals. Alternative Names: 1-Acetyl-4-benzonitrile; 4-Acetylbenzonitrile; 4-Cyanoacetophenone; 4-Cyanophenyl Methyl Ketone; 4'-Cyanoacetophenone; Methyl p-Cyanophenyl Ketone; p-Acetylbenzonitrile; p-Cyanoacetophenone; p-Cyanophenyl Methyl Ketone. Grades: Highly Purified. CAS No. 1443-80-7. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| p-Cyanoacetophenone-d4 | Labeled p-Cyanoacetophenone. Used in the preparation of antimalarial isonitriles. Group: Biochemicals. Alternative Names: 1-Acetyl-4-benzonitrile-d4; 4-Acetylbenzonitrile-d4; 4-Cyanoacetophenone-d4; 4-Cyanophenyl-d4 Methyl Ketone; 4'-Cyanoacetophenone-d4; Methyl p-Cyanophenyl-d4 Ketone; p-Acetylbenzonitrile-d4; p-Cyanoacetophenone-d4; p-Cyanophenyl-d4 Methyl Ketone. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| p-Cyanobenzylidene p-Nonyloxyaniline | CBNOA or CN.9, liquid crystal. CAS No. 67363-89-7. Pack Sizes: 1g. Product ID: FR-0486. M.P. 71 (S), 99 (N), 105 (I). Mole weight: 348.49. |  Frinton Laboratories |
| p-Cyanophenyl Isothiocyanate | p-Cyanophenyl Isothiocyanate. Group: Biochemicals. Alternative Names: 4-Cyanophenyl isothiocyanate; 4-Isothiocyanatobenzonit ri le; p-Cyanophenyl Ester Isothiocyanic Acid; 4-Isothiocyanatobenzonit ri le. Grades: Highly Purified. CAS No. 2719-32-6. Pack Sizes: 2.5g. Molecular Formula: C8H4N2S, Molecular Weight: 160.199999999999. US Biological Life Sciences. | Worldwide |
| p-Cyclopentylbenzaldehyde | p-Cyclopentylbenzaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: p-Cyclopentylbenzaldehyde, EINECS 254-923-0, CID3016187, 40452-70-8. Product Category: Heterocyclic Organic Compound. CAS No. 40452-70-8. Molecular formula: C12H14O. Mole weight: 174.238960 [g/mol]. Purity: 0.96. IUPACName: 4-cyclopentylbenzaldehyde. Canonical SMILES: C1CCC(C1)C2=CC=C(C=C2)C=O. Density: 1.058g/cm³. ECNumber: 254-923-0. Product ID: ACM40452708. Alfa Chemistry ISO 9001:2015 Certified. | |
| PCZAC | PCZAC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,10-Dihydro-9,9-dimethyl-10- (9-phenyl-9H-carbazol-3-yl)-acridine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1705584-08-2. Molecular formula: C33H26N2. Mole weight: 450.57 g/mol. Product ID: ACM1705584082. Alfa Chemistry ISO 9001:2015 Certified. Categories: PC Accelerator. | |
| pCzB-2CN | pCzB-2CN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-(9H-Carbazol-9-yl)biphenyl-3,5-dicarbonitrile. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1646323-59-2. Molecular formula: C26H15N3. Mole weight: 369.42 g/mol. Product ID: ACM1646323592. Alfa Chemistry ISO 9001:2015 Certified. | |
| PCz-BFP | PCz-BFP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(3-(9H -Carbazol-9-yl)phenyl)benzofuro[2,3-b ]pyridine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1424369-36-7. Molecular formula: C29H18N2O. Mole weight: 410.47 g/mol. Product ID: ACM1424369367. Alfa Chemistry ISO 9001:2015 Certified. | |
| PD0166285 | PD0166285 is a potent Wee1 inhibitor and Chk1 inhibitor with activity at nanomolar concentrations. This G2 checkpoint abrogation by PD0166285 was demonstrated to kill cancer cells, there at a toxic highest dose of 0.5 muM in some cell lines for exposure periods of no longer than 6 hours. The deregulated cell cycle progression may have ultimately damaged the cancer cells. We herein report one of the mechanism by which PD0166285 leads to cell death in the B16 mouse melanoma cell line. Synonyms: PD166285; 6-(2,6-dichlorophenyl)-2-((4-(2-(diethylamino)ethoxy)phenyl)amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-Dichlorophenyl)-2-[4-(2-diethylaminoethoxy)phenylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methyl-. Grades: ≥98%. CAS No. 185039-89-8. Molecular formula: C26H27Cl2N5O2. Mole weight: 512.44. | |
| PD0176078 | PD0176078 is a newly found N-type Calcium channel blocker. Uses: Scientific research. Group: Signaling pathways. CAS No. 248922-46-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00236. |  |
| PD0176078 | PD0176078 is a novel N-type calcium channel blocker. Synonyms: (2S)-N-[4,4-bis(4-fluorophenyl)butyl]-4-methyl-2-(methylamino)pentanamide; PD176078; PD 0176078; PD-0176078. CAS No. 248922-46-5. Molecular formula: C23H30F2N2O. Mole weight: 388.49. | |
| PD 0220245 | PD 0220245 is a non-peptide interleukine 8 (IL-8) receptor antagonist. Synonyms: PD 0220245; PD0220245; PD-0220245; N-[6,7-dichloro-3-(5-thiophen-2-ylthiophen-2-yl)quinoxalin-2-yl]-N',N'-diethylbutane-1,4-diamine dihydrochloride. Grades: 99%. CAS No. 640736-79-4. Molecular formula: C24H26Cl2N4S2.2HCl. Mole weight: 578.45. | |
| PD0325901 | PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. Uses: Reprogramming, self-renewal. Synonyms: PD 0325901; PD 325901. Grades: >98%. CAS No. 391210-10-9. Molecular formula: C16H14F3IN2O4. Mole weight: 482.198. | |
| PD 0332991 hydrochloride | PD 0332991 hydrochloride is a cyclin-dependent kinase (CDK) inhibitor with high affinity for CDK4 and CDK6. It has the potential for breast cancer treatment. Uses: Potential treatment of breast cancer. Synonyms: PD 0332991 hydrochloride; PD0332991 hydrochloride; PD-0332991 hydrochloride; Palbociclib HCl; Palbociclib hydrochloride; 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one hydrochloride. Grades: 99%. CAS No. 571189-11-2. Molecular formula: C24H29N7O2.37/20HCl. Mole weight: 514.99. | |
| PD 0332991 Isethionate (6-acetyl-8-cyclopentyl-5-methyl-2-[ [5- (1-piperazinyl) -2-pyridinyl]amino]pyrido [2, 3-d] pyrimidin-7(8H)-one isethionate salt) | Potent Cdk4/6 inhibitor (IC50 values are 11 and 15nm for Cdk4 and Cdk6 respectively). Selective for Cdk4/6 over a panel of 34 additional protein kinases (IC50 values are > 10um). Induces G1 cell cycle arrest and senescence in retinoblastoma protein (Rb)-proficient cell lines; blocks growth of intracranial glioblastoma multiforme xenografts in mice. Brain penetrant. Group: Biochemicals. Grades: Highly Purified. CAS No. 827022-33-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD0407824 | PD0407824 is a potent and selective inhibitor of checkpoint kinase Chk1 and WEE1 with IC50s of 47 and 97 nM, respectively. It is a BMP chemical sensitizer that increases cell sensitivity to subthreshold amounts of BMP4. It has potential anticancer activity. Synonyms: PD 407824; 9-Hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione; Pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, 9-hydroxy-4-phenyl-. Grades: ≥98%. CAS No. 622864-54-4. Molecular formula: C20H12N2O3. Mole weight: 328.32. | |
| PD089828 | PD089828 is a potent FGFR inhibitor, which inhibits human full-length fibroblast growth factor (FGF) receptor-1 (FGFR-1), platelet-derived growth factor (PDGF) receptor beta subunit (PDGFR-beta), Src nonreceptor tyrosine kinase (c-Src) and epidermal growth factor (EGF) receptor (EGFR) tyrosine kinases with half-maximal inhibitory potencies (IC50 values) of 0.15 +/- 0.02 (n = 4), 0.18 +/- 0.04 (n = 3), 1.76 +/- 0.28 (n = 4) and 5.47 +/- 0.78 (n = 6) microM, respectively. The results highlight the biological characteristics of PD 089828 as a novel, broadly active protein tyrosine kinase inhibitor with long-lasting but reversible cellular effects. The potential therapeutic use of these broadly acting, nonselective inhibitors as antiproliferative and antimigratory agents could extend to such diseases as cancer, atherosclerosis and restenosis in which redundancies in growth-signaling pathways are known to exist. Synonyms: PD-089828; PD 089828; N-[2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea; 1-[2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-(2-methyl-2-propanyl)urea; EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor. Grades: ≥98%. CAS No. 179343-17-0. Molecular formula: C18H18Cl2N6O. Mole weight: 405.28. | |
| PD 099560 | PD 099560, a benzopyran derivative, has been found to be a HIV-1 protease inhibitor that could be significant in HIV studies. Synonyms: PD-099560; PD099560; PD 099560; 4-Hydroxy-3-(3-phenoxypropyl)-2H-1-benzopyran-2-one; PD-099560; PD099560; 3PhOPr-4OHBzpyran2one. Grades: 98%. CAS No. 155758-74-0. Molecular formula: C18H16O4. Mole weight: 296.32. | |
| PD 102807 | PD 102807. Group: Biochemicals. Grades: Purified. CAS No. 23062-91-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 102807 | PD 102807 is a M4 muscarinic receptor antagonist with an IC 50 of 90.7 nM. PD 102807 inhibits M1, M2, M3, M5 muscarinic receptor with IC 50 s of 6558.7, 3440.7, 950.0, and 7411.7 nM, respectively [1]. Antidyskinetic effect. Uses: Scientific research. Group: Signaling pathways. CAS No. 23062-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107646. | |
| PD 102807 | PD 102807 is a selective mAChR M4 antagonist with IC50 values of 91, 6559, 3441, 95 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively. Synonyms: PD 102807; PD102807; PD-102807; 3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid, ethyl ester. Grades: ≥98% by HPLC. CAS No. 23062-91-1. Molecular formula: C23H24N2O4. Mole weight: 392.45. | |
| PD-113413 | PD-113413 is a metabolite of quinapril, which is an angiotensin-converting enzyme(ACE) inhibitor. It is used in the treatment of hypertension and congestive heart failure. Uses: Pd-113413 is used in the treatment of hypertension and congestive heart failure. Synonyms: PD-113413; PD113413; PD 113413; 2H-Pyrazino(1,2-b)isoquinoline-2-acetic acid, 1,3,4,6,11,11a-hexahydro-3-methyl-1,4-dioxo-alpha-(2-phenylethyl)-, (3S-(2(R*),3alpha,11abeta))-;(2S)-2-[(3S,11aS)-3-methyl-1,4-dioxo-3,6,11,11a-tetrahydropyrazino[1,2-b]isoquinolin-2-yl]-4-phenylbutanoic acid;PD113413;(S)-2-((3S,11aS)-3-methyl-1,4-dioxo-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinolin-2(6H)-yl)-4-phenylbutanoic acid. Grades: >98 %. CAS No. 103733-50-2. Molecular formula: C23H24N2O4. Mole weight: 392.45. | |
| PD-116152 | PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp. Uses: Pd-116152 has antitumor activity. Synonyms: PD-116,152; PD116,152; PD 116,152; PD116152; PD 116152; 6-Formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid methyl ester; Methyl 6-formyl-4,7,9-trihydroxy-8-methylphenazine-1-carboxylate. Grades: >98 %. CAS No. 101708-64-9. Molecular formula: C16H12N2O6. Mole weight: 328.28. | |
| PD-116779 | PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class. Uses: Pd-116779 is a novle antitumor antibiotic. Synonyms: PD116,779; PD 116,779; PD-116,779; PD116779; PD 116779; 3,4-Dihydro-2,3,8-trihydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; 2,3,8-Trihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. Grades: >98 %. CAS No. 102674-89-5. Molecular formula: C19H14O6. Mole weight: 338.31. | |
| PD-117302 | PD-117302, a new nonpeptide opioid compound, is a selective kappa-opioid agonist. It has been evaluated in vivo for antinociceptive activity and other effects characteristic of kappa-receptor activation. It also causes naloxone-reversible locomotor impairment and diuresis. It is used as an Anticonvulsants, an Anti-Arrhythmia agent, a Central Nervous System agent and a Cardiovascular agent. Uses: Pd-117302 is used as an anticonvulsants, an anti-arrhythmia agent, a central nervous system agent and a cardiovascular agent. Synonyms: PD117302; PD-117302; PD 117302; Trans-N-Methyl-N-(2-(1-pyrrolidinyl)cyclohexyl-)benzo-(b)-thiophene-4-acetamide;Benzo(b)thiophene-4-acetamide, N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)-, trans-(+-)-;2-(1-Benzothiophen-4-yl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide;PD117302. Grades: >98%. CAS No. 111728-01-9. Molecular formula: C21H28N2OS. Mole weight: 356.52. | |
| PD 118057 | PD 118057. Group: Biochemicals. Grades: Purified. CAS No. 313674-97-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 118057 | PD 118057 is a human ether-a-go-go (hERG) KV11.1 potassium channel activator, with no major effect on INa, ICa/L, IK1 and IKs currents. PD-118057prevents and reverses QT interval prolongation; Compounds such as PD-118057 may offer new approach in the treatment of delayed repolarization conditions, which occur in inherited or acquired long QT syndrome and congestive heart failure. Synonyms: 2-[[4-[2- (3, 4-Dichlorophenyl) ethyl]phenyl]amino]benzoic acid; PD-118057; PD118057; PD 118057. Grades: ≥99% by HPLC. CAS No. 313674-97-4. Molecular formula: C21H17Cl2NO2. Mole weight: 386.27. | |
| PD-118440 | PD-118440 is a dopamine antagonist. It was identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests including [3H]-haloperidol and [3H]-N-propylnorapomorphine binding. It inhibits striatal DA synthesis, DA neuronal firing and spontaneous locomotor activity. Synonyms: 2-Amino-4-[(1-propyl-1,2,5,6-tetrahydropyridin)-3-yl]thiazole;2-Thiazolamine,4-(1,2,5,6-tetrahydro-1-propyl-3-pyridinyl)-;4-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,3-thiazol-2-amine; PD118440; PD 118440; PD118440. Grades: >98%. CAS No. 108351-90-2. Molecular formula: C11H17N3S. Mole weight: 223.33. | |
| PD-118576 | PD-118576 is an antitumor macrolide antibiotic produced by Streptomyces sp. WP 3913. It exhibits moderate activity against bacteria and fungi. Synonyms: PD 118576; PD118576; PD-118,576; PD 118,576; PD118,576. CAS No. 100632-37-9. Molecular formula: C33H52O8. Mole weight: 576.8. | |
| PD-118717 | PD-118717 is a putative piperazinyl benzopyranone dopamine autoreceptor(DA) agonist. It has the profile of a DA autoreceptor agonist in neurochemical and neurophysiological tests. It has antipsychotic efficacy without neurological side effect liability in preclinical behavioral tests. Uses: Pd-118717 has antipsychotic efficacy. Synonyms: PD-118717; PD 118717; PD118717; 2H-1-Benzopyran-2-one,7-[3-[4-(2-pyrimidinyl)-1-piperazinyl]propoxy]-;7-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propoxy]chromen-2-one sulfuric acid;PD118717;7-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one sulfate. Grades: >98 %. CAS No. 104229-37-0. Molecular formula: C20H24N4O7S. Mole weight: 464.49. | |
| PD-119819 | PD-119819, a heterocyclic piperazine, is an extremely selective DA autoreceptor agonist. It binds [3H]haloperidol in tests in rats. It inhibits of spontaneous locomotor activity and inhibits of brain DA synthesis or neuronal firing in tests in rats. Synonyms: 4H-1-Benzopyran-4-one,7-[3-[4-(2-pyridinyl)-1-piperazinyl]propoxy]-, hydrochloride (1:2);7-[3-(4-pyridin-2-ylpiperazin-1-yl)propoxy]chromen-4-one;PD119819; PD-119819; PD 119819. Grades: >98 %. CAS No. 105277-43-8. Molecular formula: C21H23N3O3. Mole weight: 365.43. | |
| PD-120697 | PD-120697 is a novel dopamine antagonist with central dopamine agonist properties. It was identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests including [3H]-haloperidol and [3H]-N-propylnorapomorphine binding. It inhibits striatal DA synthesis, DA neuronal firing and spontaneous locomotor activity. Synonyms: PD-120697; PD120697; PD 120697; 4-(1,2,5,6-Tetrahydro-1-allyl-3-pyridinyl)-2-thiazolamine;2-Thiazolamine, 4-[1,2,5,6-tetrahydro-1-(2-propen-1-yl)-3-pyridinyl]-;4-(1-Prop-2-enyl-3,6-dihydro-2H-pyridin-5-yl)-1,3-thiazol-2-amine;PD120697;4-(1-Allyl-1,2,5,6-tetrahydropyridin-3-yl)thiazol-2-amine. Grades: >98%. CAS No. 108351-91-3. Molecular formula: C11H15N3S. Mole weight: 221.32. | |
| PD 121373 | This active molecular has a Benzothiopyrano-indazole structure and the benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations. PD 121373 made DNA single- and double-strand breaks in a time and concentration-dependent manner in L1210 cells. In 2003, PD 121373 was in Phase-II for Colorectal cancer, Solid tumours and Prostate cancer in USA. Uses: Treatment of colorectal cancer; prostate cancer; solid tumours. Synonyms: PD 121373; PD-121373; PD121373; 5-((2-aminoethyl)amino)-2-(2-(diethylamino)ethyl)-2H-thiochromeno[4,3,2-cd]indazol-9-ol,Sedoxantrone. Grades: 98%. CAS No. 113457-06-0. Molecular formula: C21H27N5OS. Mole weight: 397.54. | |
| PD 122860 | This active molecular is a calcium channel antagonist with sodium channel stimulating property as a dihydropyridine. PD 122860 can increase left ventricular contractility, decrease coronary resistance and alter the shape of the electrocardiogram T-wave in the animal model. PD 122860 can relax potassium-contracted aortic rings selectively and inhibit [3H] nitrendipine binding to rat brain membranes. But it is discontinued for Heart failure and Ischaemic heart disorders preclinical treatment in USA in 2000. Uses: Heart failure; ischaemic heart disorders. Synonyms: PD122860; PD-122860; PD 122860; ethyl 5-cyano-6-methyl-2-((pyridin-4-ylsulfonyl)methyl)-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate. Grades: 98%. CAS No. 122576-86-7. Molecular formula: C23H20F3N3O4S. Mole weight: 491.48. | |
| PD 123177 | PD 123177 is a Nonpeptide angiotensin type 2 receptor inhibitor. In Dec 1995, Preclinical development of it for cardiovascular disorders was began in USA. Uses: Cardiovascular disorders. Synonyms: Exp 655; Exp655; Exp-655; PD123177; PD-123177; PD 123177,1-[(4-amino-3-methylphenyl)methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid. Grades: 98%. CAS No. 114785-12-5. Molecular formula: C29H28N4O3. Mole weight: 480.56. | |
| PD123319 | PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. Uses: Vasoconstrictor agents. Synonyms: PD123319; PD 123319; PD-123319; (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (S)-(+)-PD 123319; PD 123319. Grades: >98%. CAS No. 130663-39-7. Molecular formula: C31H32N4O3. Mole weight: 508.61. | |
| PD-123319 Bis(trifluoroacetate) Salt Hydrate | A selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-α-induced damage to human renal proximal tubular epithelial cells. Group: Biochemicals. Alternative Names: (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319 Bis(trifluoroacetate) Salt Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD 123319 ditrifluoroacetate | PD 123319 ditrifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 130663-39-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 123319 ditrifluoroacetate | PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC 50 of 34 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 136676-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10259A. | |
| PD-123319 TFA salt | The ditrifluoroacetate salt form of PD-123319, a nonpeptide AT2R antagonist, could have potential effect against hypertension. It has already been discontinued by Pfizer for the study of hypertension. IC50: 34 nM. Uses: The ditrifluoroacetate salt form of pd-123319 is a nonpeptide at2r antagonist that could have potential effect against hypertension. Synonyms: (S)-1-(4-(dimethylamino)-3-methylbenzyl)-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid compound with 2,2,2-trifluoroacetic acid (1:2); PD-123319; PD 123319; PD123319; PD-123319 TFA; PD 123319 ditrifluoroacetate. Grades: 98%. CAS No. 136676-91-0. Molecular formula: C35H34F6N4O7. Mole weight: 736.66 (anhydrous basis). | |
| PD 125754 | This active molecular is a Renin inhibitor that applicated in treatment of essential hypertension. Uses: Essential hypertension. Synonyms: PD125754; PD-125754; PD 125754; tert-butyl ((2S,3S)-6-(((2S,3S)-5-(((S)-1-((3-(aminomethyl)benzyl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-cyclohexyl-3-hydroxy-5-oxopentan-2-yl)amino)-3-hydroxy-6-oxo-1-phenylhexan-2-yl)carbamate. Grades: 98%. CAS No. 124339-32-8. Molecular formula: C42H65N5O7. Mole weight: 752.00. | |
| PD 125967 | PD 125967 is a renin inhibitor which may be useful for treatment of essential hypertension. Uses: Essential hypertension. Synonyms: PD125967; PD-125967; PD 125967; 5-(3-(1H-imidazol-4-yl)-2-(3-(naphthalen-1-yl)-2-(naphthalen-1-ylmethyl)propanamido)propanamido)-6-cyclohexyl-4-hydroxy-2-isobutyl-N-(2-methylbutyl)hexanamide. Grades: 98%. CAS No. 128139-14-0. Molecular formula: C51H67N5O4. Mole weight: 814.12. | |
| PD 127443 | This active molecular is a Leukotriene B4 antagonist. PD- 127443 is also a 5-lipoxygenase and cyclooxygenase inhibitor and it has been reported to have antiinflammatory effects in vivo. Uses: Antiinflammatory. Synonyms: PD-127443; PD127443; PD 127443; (E)-2,6-di-tert-butyl-4-(2-(5-methyl-1H-pyrazol-3-yl)vinyl)phenol. Grades: 98%. CAS No. 121502-05-4. Molecular formula: C20H28N2O. Mole weight: 312.45. | |
| PD-128763 | PD-128763 is a selective inhibitor of poly(ADP-ribose) polymerase. Synonyms: PD 128763; PD128763; 3,4-Dihydro-5-methyl-1(2H)-isoquinolinone; 3,4-dihydro-5-methylisoquinolinone. Grades: 0.98. CAS No. 129075-56-5. Molecular formula: C10H11NO. Mole weight: 161.20. | |
| PD 128907 | PD 128907 is a selective D2 and D3 dopamine receptor agonist that can be used as an antipsychotic. Uses: Antipsychotic. Synonyms: PD 128907; PD128907; PD-128907; 4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol; 2H,5H-[1]Benzopyrano[4,3-b]-1,4-oxazin-9-ol,3,4,4a,10b-tetrahydro-4-propyl-, (4aS,10bS)-rel-; 3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol. Grades: 99%. CAS No. 123594-64-9. Molecular formula: C14H19NO3. Mole weight: 249.31. | |
| PD128907 HCl | PD 128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. Synonyms: PD 128907 HCl; PD-128907 HCl. Grades: >98%. CAS No. 112960-16-4. Molecular formula: C14H20ClNO3. Mole weight: 285.77. | |
| PD 128907 hydrochloride | PD 128907 (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 112960-16-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100539A. | |
| PD 130883 | This active molecular is a potent lipophilic quinazoline antifolate and data show that marked PD130883 suppression of thymidylate synthase slows the rate but not the extent of tetrahydrofolate cofactor interconversion to dihydrofolate upon complete suppression of dihydrofolate reductase with trimetrexate. Synonyms: CHEMBL62769;123685-36-9;2-Amino-6-(((4-nitrophenyl)-2-propynylamino)methyl)-4(3H)quinazolinone;4(3H)-Quinazolinone,2-amino-6-[[(4-nitrophenyl)-2-propyn-1-ylamino]methyl]-;ACMC-20mqpf;PD-130883; PD130883; PD 130883. Grades: 95%. CAS No. 123685-36-9. Molecular formula: C18H15N5O3. Mole weight: 349.34. | |
| PD 130908 | PD 130908 is an effective hypoxic cytotoxin as an analogue of RSU 1069, but less potent than the hypoxic cell radiosensitizer RSU 1069. Toxicity toward hypoxic tumor cells in vivo is demonstrated by clamping tumors (for 60 min) following administration of PD 130908. No development was reported for the treatment of cancer. Uses: Cancer. Synonyms: PD-130908; PD130908; PD 130908; N-(2-bromoethyl)-3-(2-nitro-1H-imidazol-1-yl)propan-1-amine hydrobromide. Grades: 98%. CAS No. 131505-02-7. Molecular formula: C8H14Br2N4O2. Mole weight: 358.03. | |
| PD 131628 | PD 131628 is a new fluoroquinolone as the bioactive form of PD 131112 which is a antibacterial agent originated by Pfizer. PD 131112 can be used for the treatment of infections with penicillin-resistant and -susceptible pneumococci, but no development has been published yet. Uses: Bacterial infections. Synonyms: PD-131628; PD131628; PD 131628; (S)-7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid. Grades: 98%. CAS No. 127967-03-7. Molecular formula: C16H17FN4O3. Mole weight: 332.33. | |
| PD 132002 | PD 132002 is a renin inhibitor originated by Pfizer. In Dec 2001, clinical trials for Hypertension in USA was discontinued. Uses: Hypertension. Synonyms: PD-132002; PD132002; PD 132002; (2R)-methyl 3-amino-2-((2S)-N-((2S,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl)-2-(morpholine-4-sulfonamido)-3-phenylpropanamido)-3-oxopropanoate. Grades: 98%. CAS No. 134452-04-3. Molecular formula: C31H50N4O9S. Mole weight: 654.81. | |
| PD 134922 | PD 134922 has been found to be a HIV-1 protease inhibitor that could probably be effective against HIV infections. Synonyms: PD-134922; PD134922; PD 134922; AC1L3V1C; DTXSID30164523; AM008268; (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]pent-4-enoyl]amino]-2-propan-2-ylhexanamide. Grades: 98%. CAS No. 150351-30-7. Molecular formula: C37H61N5O7S. Mole weight: 719.98. | |
| PD 135158 | PD 135158. Group: Biochemicals. Grades: Purified. CAS No. 130285-87-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 135158 | PD 135158 is a nonpeptide CCK2 receptor antagonist. It also exhibits agonist activity at the rat pancreatic CCKA receptor to stimulate pancreatic enzyme secretion. Uses: Anti-anxiety agents. Synonyms: 4-[[(1R)-2-[[(2R)-3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[[[(1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl]oxy]carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid. Grades: ≥98% by HPLC. CAS No. 130285-87-9. Molecular formula: C35H44N4O6. Mole weight: 616.76. | |
| PD 135390 | PD 135390 has been found to be a HIV-1 protease inhibitor that could probably be effective against HIV infections. Synonyms: PD-135390; PD135390; PD 135390; 5-((2S)-N-(1-(allylthio)-2-amino-2-oxoethyl)-2-(morpholine-4-sulfonamido)-3-phenylpropanamido)-N-butyl-6-cyclohexyl-4-hydroxy-2-isopropylhexanamide. Grades: 98%. CAS No. 150351-31-8. Molecular formula: C37H61N5O7S2. Mole weight: 752.04. | |
| PD 136450 | PD-136,450 is a Cholecystokinin type B receptor antagonist originated by Pfizer. It is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. It has therapeutic potential as acid antisecretory drugs, and may be of use as adjuvant therapy for gastrin sensitive tumours. No development for the treatment of Peptic ulcer was reported. Uses: Peptic ulcer. Synonyms: Cam 1189; Cam-1189; Cam1189; PD-136450; PD136450; PD 136450;(E)-4-((2-(2-(((adamantan-2-yloxy)carbonyl)amino)-3-(1H-indol-3-yl)-2-methylpropanamido)-1-phenylethyl)amino)-4-oxobut-2-enoic acid. Grades: 98%. CAS No. 139067-52-0. Molecular formula: C35H40N4O6. Mole weight: 612.72. | |
| PD 138142 | PD 138142 is a water soluble Sterol O-acyltransferase inhibitor. Triacylglycerol secretion is decreased in the presence of PD-138142-15. Preclinical development for Hypercholesterolaemia in USA was discontinued. Uses: Hypercholesterolaemia. Synonyms: PD-138142; PD138142; PD 138142; 2,6-diisopropylphenyl (2,6-diisopropylphenoxy)carbonylsulfamate. Grades: 98%. CAS No. 142642-31-7. Molecular formula: C25H35NO5S. Mole weight: 461.62. | |
| PD-138312 | PD-138312 is a novel broad-spectrum 7-pyrrolidinyl fluoronaphthyridines with a difluorophenyl substitution or a cyclopropyl at the 1 positions, respectively. It has been demonstrated to have excellent therapeutic potential against clinically important gram-positive pathogens in vitro activity. It was evaluated for its in vivo potencies against acute systemic infections and pneumococcal in mice pneumonia model. Uses: Pd-138312 has been demonstrated to have excellent therapeutic potential against clinically important gram-positive pathogens. Synonyms: PD-138312; PD138312; PD 138312;7-(3-(2-Aminopropan-2-yl)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid;7-(3-(1-Amino-1-methylethyl)-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid. Grades: >98%. CAS No. 107334-06-5. Molecular formula: C19H23FN4O3. Mole weight: 374.41. | |
| PD 140248 | PD 140248, a fluoronaphthyridine compound, has been found to have potential antibacterial effect especially against gram-positive pathogens. It has not been reported about its development status since 2000. Synonyms: PD-140248; PD140248; PD 140248; 7-(3-(1-Aminoethyl)-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; 1,8-Naphthyridine-3-carboxylic acid, 7-(3-(1-aminoethyl-1-pyrrolidinyl))-1-(2,4-difluorophenyl)-6-fluoro-1,4-d. Grades: 98%. CAS No. 147208-55-7. Molecular formula: C21H19F3N4O3. Mole weight: 432.39. | |
| PD-140376 | PD-140376 has been found to be a cholecystokininB/gastrin receptor antagonist that could probably be useful in the study of sorts of gastrointestinal disorders. Synonyms: PD-140376; PD 140376; AC1L52KZ; 3-((4-Aminophenyl)methyl)-N-(alpha-methyl-N-((tricyclo(3.3.1.1)dec-2-yloxy)carbonyl)-D-tryptophyl)-beta-alanine; OR223333. Grades: 98%. CAS No. 149027-97-4. Molecular formula: C33H40N4O5. Mole weight: 572.71. | |
| PD 142505-0028 | PD 142505-0028, also know as CI-1017, has been found to be a muscarinic agonist that could exhibit effect against cognition disorder so that was once studied in AD. Synonyms: CI-1017; CI1017; CI 1017; PD-142505-0028; PD42505-0028; PD 142505-0028; CTK4D0956; 1-Azabicyclo[2.2.1]heptan-3-one,O-[3-(3-methoxyphenyl)-2-propyn-1-yl]oxime. Grades: 98%. CAS No. 161774-09-0. Molecular formula: C18H20N2O6. Mole weight: 360.36. | |
| PD 144418-d7 Oxalate | PD 144418-d7 Oxalate. Group: Biochemicals. Alternative Names: 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine-d7 Oxalate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H17D7N2O5, Molecular Weight: 379.46. US Biological Life Sciences. | Worldwide |
| PD 144418 oxalate | PD 144418 oxalate is a very selective sigma 1 agent (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively), devoid of any significant affinity for other receptors and that sigma 1 site may modulate actions in the CNS. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration, and also attenuates cocaine-induced hyperactivity in mice. Synonyms: PD 144418 oxalate; PD144418 oxalate; PD-144418 oxalate; 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate. Grades: ≥98% by HPLC. CAS No. 154130-99-1. Molecular formula: C18H22N2O.C2H2O4. Mole weight: 372.42. | |
| PD 145305 | PD 145305 is an inactive analog of PD 150606, a selective calpain inhibitor. Synonyms: 3-phenyl-2-sulfanylpropanoic acid; Benzylthioglykolsaure. Grades: ≥95%. CAS No. 90536-15-5. Molecular formula: C9H10O2S. Mole weight: 182.2. | |
| PD 146176 | PD 146176 is a specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM), without effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC50 = 0.54 μM for 15-LOX in rabbit reticulocytes). It is known that PD-146176 acts as a noncompetitive inhibitor towards 15-LO, displaying a Ki=197 nM. Furthermore, PD-146176 reduces monocyte macrophage enrichment of atherosclerotic lesions and development of fibrofoamy and fibrous plaque. Synonyms: 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole; PD 146176; PD-146176; PD146176; NSC 168807; NSC-168807; NSC168807. Grades: ≥98% by HPLC. CAS No. 4079-26-9. Molecular formula: C15H11NS. Mole weight: 237.32. | |
| PD 146176 | PD 146176. Group: Biochemicals. Grades: Purified. CAS No. 4079-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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