A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PDE1-IN-1 is a potent PDE1 inhibitor and neuroprotective agent. Synonyms: PDE1-IN-1. Grades: >98%. CAS No. 1160521-50-5. Molecular formula: C29H26FN7O. Mole weight: 507.56.
PDE1-IN-2
PDE1-IN-2 is an inhibitor of PDE1 that has IC50 values of 6, 140 and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. Synonyms: PDE1 IN 2; 6-bromo-7-(cyclopentylmethyl)-3-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]pyrazin-8-one. CAS No. 1904611-63-7. Molecular formula: C16H21BrN4O2. Mole weight: 381.27.
A cell permeable, potent, and selective oxime PDE4D inhibitor (IC50=0.67uM) which displays much reduced activities toward other PDE4 isoforms. It is shown to cause a significant 40% increase in extracellular cAMP in the hippocampus of freely moving rats in vivo at 100uM, but has no effect on Ab levels. This compound elicits cognitive enhancement in vivo at the optimum dose of 0.003mg/kg in both mice and rat models, and unlike rolipram, does not cause emesis-like behavior in rodents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PDE5A1 active from Mouse, Recombinant
Mouse PDE5A (GenBank Accession No. NM_153422) full length with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Mouse pde5a (genbank accession no. nm_153422) full length with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Purity: > 70% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Cat No: NATE-0528.
PDE-9 inhibitor is useful for neurodegenerative diseases. Synonyms: PDE 9 inhibitor; PDE9 inhibitor; PDE-9 inhibitor. Grades: >98%. CAS No. 1082743-70-1. Molecular formula: C22H27N5O2. Mole weight: 393.48.
PDE-9 inhibitor
PDE-9 inhibitor is useful for neurodegenerative diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1082743-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-50865.
PDE9-IN-(S)-C33
PDE9-IN-(S)-C33 is a potent and selective inhibitor of phosphodiesterase-9 (PDE9). Uses: Designed for use in research and industrial production. Additional or Alternative Names: PDE9-IN-(S)-C33; PDE9IN(S)C33; PDE9 IN (S) C33; (S)-C33. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2066488-39-7. Molecular formula: C18H20ClN5O. Mole weight: 357.84. Purity: >98%. IUPACName: 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one. Canonical SMILES: O=C1C2=C(N(C3CCCC3)N=C2)N=C(N[C@H](C4=CC=C(Cl)C=C4)C)N1. Product ID: ACM2066488397. Alfa Chemistry ISO 9001:2015 Certified.
An inhibitor of phosphodiesterase IV with potential for the treatment of asthma, COPD or other inflammatory diseases. Synonyms: 9H-Purine, 2-chloro-9-[[3-(cyclopentyloxy)-4-methoxyphenyl]methyl]-6,8-dimethyl-; 2-chloro-9-[(3-cyclopentyloxy-4-methoxyphenyl)methyl]-6,8-dimethylpurine. CAS No. 225100-12-9. Molecular formula: C20H23ClN4O2. Mole weight: 386.88.
PDGF-AA from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
PDGF-BB from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
PDGF-BB human
Animal-component free, recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
PDGF-CC human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
An orally bioavailable amino-triazole compound that is shown to bind to the inactive conformations of both PDGFRb and Raf kinases (allosteric, Type II inh), and acts as a potent inhibitor of Flt3, Kit, PDGFRa and PDGFRb (=52, 170, 300 and 520nM, respectively) with selectivity over B-Raf, p38a, FGFR2 and VEGFR2 (>10uM) in a multi-kinase panel. Completely blocks the phosphorylations of MEK-1/2 S217/S221, ERK-1/2 T202/Y204 in FGF-stimulated HUVECs, PDGFRb in PDGF-BB-stimulated VSMCs, ERK-1/2 T202/Y204 in 1205Lu-B Raf V600E cells, and C-Raf S338 at 10uM. Reduces FGF-induced angiogenesis in mouse Matrigel model (50mg/kg, i.p., bid) and selectively induces apoptosis in the endothelium; further, suppresses orthotopic renal cell carcinoma growth in mice (100mg/kg, p.o., qd). Group: Biochemicals. Alternative Names: 6- (4- (5- (3- (Trifluoromethyl) phenylamino) -4 H-1,2,4-triazol-3-yl)phenoxy)-2-(methylthio)pyrimidin-4-amine, PDGFR Tyrosine Kinase Inhibitor XXII. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?OS, Molecular Weight: 459.6. US Biological Life Sciences.
The PDGFR?/RAF Kinase Inhibitor controls the biological activity of PDGFR?/RAF Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PDGFR Tyrosine Kinase Inhibitor II - CAS 249762-74-1
The PDGFR Tyrosine Kinase Inhibitor II, also referenced under CAS 249762-74-1, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PDGFR Tyrosine Kinase Inhibitor V - CAS 347155-76-4
The PDGFR Tyrosine Kinase Inhibitor V, also referenced under CAS 347155-76-4, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PDGFR Tyrosine Kinase Inhibitor VII - CAS 251356-45-3
The PDGFR Tyrosine Kinase Inhibitor VII, also referenced under CAS 251356-45-3, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5
The PDGFR Tyrosine Kinase Inhibitor VI, SU6668, also referenced under CAS 210644-62-5, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
pdGp
pdGp, also known as pyruvate dehydrogenase kinase, is a remarkably efficacious and highly targeted inhibitor of the glycogen phosphorylase (Gp). Synonyms: 2'- Deoxyguanosine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 16174-59-7. Molecular formula: C10H15N5O10P2. Mole weight: 427.2.
Pd/graphene nanocomposite
Pd/graphene nanocomposite. Uses: Perfect for transmission electron microscopy imaging standard. a catalytic material to be used in fuel cells, ch4 gas sensor. Group: 3d printing materials carbon nano materials.
Pd/graphene nanocomposite
10 mg/mL, dispersion in acetone. Group: Nanomaterials for 3d printing.
PDHA1 (30-390), His tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.