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| Product | Description | |
|---|---|---|
| Pemetrexed disodium heptahydrate | Pemetrexed disodium heptahydrate is a novel antifolate , the K i values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase ( TS ), dihydrofolate reductase ( DHFR ), and glycinamide ribonucleotide formyltransferase ( GARFT ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY231514 disodium heptahydrate. CAS No. 357166-29-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10820B. |  |
| Pemetrexed Disodium Heptahydrate | Pemetrexed Disodium Heptahydrate. Group: Biochemicals. Alternative Names: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt Heptahydrate. Grades: Highly Purified. CAS No. 357166-29-1. Pack Sizes: 10mg. Molecular Formula: C20H33N5Na2O13, Molecular Weight: 597.48. US Biological Life Sciences. |  Worldwide |
| Pemetrexed Disodium Heptahydrate | Pemetrexed disodium is an chemotherapy drug identified as a highly efficient substrate for folylpolyglutamate synthase, potently inhibits multiple folate-dependent enzymes involved in both purine and pyrimidine synthesis including thymidylate synthase (Ki = 109 nM). Uses: A novel antifolate and antimetabolite for ts, dhfr and garft with ki of 1.3 nm, 7.2 nm and 65 nm, respectively. Synonyms: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt Heptahydrate; Pemetrexed (sodium salt hydrate); L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-8 oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. Grades: > 98%. CAS No. 357166-29-1. Molecular formula: C20H33N5Na2O13. Mole weight: 597.48. |  |
| Pemetrexed Disodium Hepthydrate | Pemetrexed Disodium Hepthydrate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 357166-29-1. Molecular Formula: C20H33N5Na2O13. Mole Weight: 597.49. Catalog: APB357166291. |  |
| Pemetrexed Disodium Hydrate | Pemetrexed Disodium Hydrate. Group: Biochemicals. Alternative Names: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-Glutamic Acid Disodium Hydrate. Grades: Highly Purified. CAS No. 357166-30-4. Pack Sizes: 10mg. Molecular Formula: C20H19Na2N5O6 5/2 H2O, Molecular Weight: 471.37. US Biological Life Sciences. | Worldwide |
| Pemetrexed disodium Impurity 13 | Pemetrexed disodium Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid. CAS No. 137281-39-1. Molecular Formula: C15H14N4O3. Mole Weight: 298.3. Catalog: APB137281391. | |
| Pemetrexed disodium Impurity 30 | Pemetrexed disodium Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate. Molecular Formula: C24H29N5O6. Mole Weight: 483.52. Catalog: APB01398. | |
| Pemetrexed disodium salt | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C20H19N5Na2O6. CAS No. 150399-23-8. Prepack ID 23048138-1g. Molecular Weight 471.37. See USA prepack pricing. |  |
| Pemetrexed, Disodium Salt, Heptahydrate (N-[4-[(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium, LY-231514, Alimta) | Pemetrexed inhibits dihydrofolate reductase, thymidylate synthase and glycinamide ribonucleotide formyltransferase with Ki values of 7nM, 109nM and 9.3uM, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 357166-29-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed EP Impurity A | Pemetrexed EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 869791-42-4. Molecular Formula: C21H23N5O6. Mole Weight: 441.44. Catalog: APB869791424. | |
| Pemetrexed EP Impurity B | Pemetrexed EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1802552-04-0. Molecular Formula: C40H40N10O13. Mole Weight: 868.82. Catalog: APB1802552040. | |
| Pemetrexed EP Impurity B | Pemetrexed EP Impurity B is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (R)-Pemetrexed EP Isomer; (2S, 2'S)-2, 2'- ( (4, 4'- ( ( (R)-2, 2'-Diamino-4, 4', 6-trioxo-4, 4', 5, 6, 7, 7'-hexahydro-1H, 1'H-[5, 6'-bipyrrolo[2, 3-d]pyrimidine]-5, 5'-diyl)bis (ethane-2, 1-diyl))bis (benzoyl))bis (azanediyl))dipentanedioic Acid. Grades: > 98%. CAS No. 1802552-04-0. Molecular formula: C40H40N10O13. Mole weight: 868.80. | |
| Pemetrexed EP Impurity C | Pemetrexed EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1802552-16-4. Molecular Formula: C40H40N10O13. Mole Weight: 868.82. Catalog: APB1802552164. | |
| Pemetrexed EP Impurity D | Pemetrexed EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1265908-59-5(Trisodium Salt); (S)-2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-4-carboxybutanamido)pentanedioic acid. CAS No. 144051-68-3. Molecular Formula: C25H28N6O9. Mole Weight: 556.52. Catalog: APB144051683. | |
| Pemetrexed EP Impurity D Trisodium Salt | Pemetrexed EP Impurity D Trisodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1265908-59-5. Molecular Formula: C25H25N6Na3O9. Mole Weight: 622.48. Catalog: APB1265908595. | |
| Pemetrexed EP Impurity E | Pemetrexed EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid. CAS No. 182009-04-7. Molecular Formula: C20H21N5O6. Mole Weight: 427.41. Catalog: APB182009047. | |
| Pemetrexed EP Impurity E Disodium Salt | Pemetrexed EP Impurity E Disodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 937370-10-0. Molecular Formula: C20H19N5Na2O6. Mole Weight: 471.38. Catalog: APB937370100. | |
| Pemetrexed Impurity | Cas No. 204257-65-8. | |
| Pemetrexed Impurity 1 | Pemetrexed Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3140-73-6. Molecular Formula: C5H6ClN3O2. Mole Weight: 175.57. Catalog: APB3140736. | |
| Pemetrexed Impurity 10 | Pemetrexed Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H16N4O3. Mole Weight: 312.33. Catalog: APB10801. | |
| Pemetrexed Impurity 11 | Pemetrexed Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 193265-47-3. Molecular Formula: C15H14N4O4. Mole Weight: 314.3. Catalog: APB193265473. | |
| Pemetrexed Impurity 12 | Pemetrexed Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H29N5O6. Mole Weight: 483.53. Catalog: APB10803. | |
| Pemetrexed Impurity 13 | Pemetrexed Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H31N5O6. Mole Weight: 497.55. Catalog: APB10804. | |
| Pemetrexed Impurity 14 | Pemetrexed Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 31469-62-2. Molecular Formula: C5H8N4O. Mole Weight: 140.15. Catalog: APB31469622. | |
| Pemetrexed Impurity 15 | Pemetrexed Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H14N4O3. Mole Weight: 298.3. Catalog: APB10805. | |
| Pemetrexed Impurity 16 | Pemetrexed Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H14N4O3. Mole Weight: 298.3. Catalog: APB10806. | |
| Pemetrexed Impurity 19 | Pemetrexed Impurity 19 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C25H28N6O9. Mole weight: 556.52. | |
| Pemetrexed Impurity 25 | Pemetrexed Impurity 25 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C8H10N4O4. Mole weight: 226.19. | |
| Pemetrexed Impurity 26 | Pemetrexed Impurity 26 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C14H15N5O3. Mole weight: 301.30. | |
| Pemetrexed Impurity 27 | Pemetrexed Impurity 27 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C15H15N5O4. Mole weight: 329.31. | |
| Pemetrexed Impurity 28 | Pemetrexed Impurity 28 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Impurity 24. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 29 | Pemetrexed Impurity 29 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 3 | An impurity of Pemetrexed which binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Grades: > 95%. CAS No. 229470-22-8. Molecular formula: C17H21N5O5. Mole weight: 375.39. | |
| Pemetrexed Impurity 3 | Pemetrexed Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123910-88-3. Molecular Formula: C12H16O3. Mole Weight: 208.26. Catalog: APB123910883. | |
| Pemetrexed Impurity 30 | Pemetrexed Impurity 30 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C31H40N6O9. Mole weight: 640.68. | |
| Pemetrexed Impurity 30 (4-Methylbenzenesulfonate) | Pemetrexed Impurity 30 (4-Methylbenzenesulfonate). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate 4-methylbenzenesulfonate. CAS No. 165049-28-5. Molecular Formula: C24H29N5O6. Mole Weight: 483.52. Catalog: APB165049285. | |
| Pemetrexed Impurity 31 | Pemetrexed Impurity 31 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C27H34N6O6. Mole weight: 538.59. | |
| Pemetrexed Impurity 32 | Pemetrexed Impurity 32 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 33 | Pemetrexed Impurity 33 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. CAS No. 1417656-72-4. Molecular formula: C20H23N5O9. Mole weight: 477.42. | |
| Pemetrexed Impurity 34 | Pemetrexed Impurity 34 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H23N5O9. Mole weight: 477.42. | |
| Pemetrexed Impurity 35 | Pemetrexed Impurity 35 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H23N5O9. Mole weight: 477.42. | |
| Pemetrexed Impurity 36 | Pemetrexed Impurity 36 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 37 | Pemetrexed Impurity 37 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: 3-(4-carboxyphenyl)-propionaldehyde ethyl ester; 4-(3-oxopropyl)benzoic acid ethyl ester; 4-ethoxycarbonylhydrocinnamal; 3-(4-carbethoxyphenyl)propanal. Grades: ≥ 95%. CAS No. 151864-81-2. Molecular formula: C12H14O3. Mole weight: 206.24. | |
| Pemetrexed Impurity 38 | Pemetrexed Impurity 38 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C12H12O4. Mole weight: 220.22. | |
| Pemetrexed Impurity 4 | An impurity of Pemetrexed which is a chemotherapy drug. Grades: > 95%. Molecular formula: C15H17N5O5. Mole weight: 347.33. | |
| Pemetrexed Impurity 4 | Pemetrexed Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 240407-05-0. Molecular Formula: C12H14O3. Mole Weight: 206.24. Catalog: APB240407050. | |
| Pemetrexed Impurity 42 | Pemetrexed Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-diethyl 2-((S)-4-amino-5-ethoxy-5-oxopentanamido)pentanedioate. Molecular Formula: C16H28N2O7. Mole Weight: 360.4. Catalog: APB01399. | |
| Pemetrexed Impurity 5 | Pemetrexed Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 221558-73-2. Molecular Formula: C12H15NaO6S. Mole Weight: 310.3. Catalog: APB221558732. | |
| Pemetrexed Impurity 5 | An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C24H32N6O8. Mole weight: 532.56. | |
| Pemetrexed Impurity 50 | Pemetrexed Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Pemetrexed Acid Methyl Ester; methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. CAS No. 155405-80-4. Molecular Formula: C16H16N4O3. Mole Weight: 312.32. Catalog: APB155405804. | |
| Pemetrexed Impurity 51 | Pemetrexed Impurity 51. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium 4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. Molecular Formula: C15H13N4O3·Na. Mole Weight: 320.28. Catalog: APB02189. | |
| Pemetrexed Impurity 6 | Pemetrexed Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 155405-79-1. Molecular Formula: C12H13BrO3. Mole Weight: 285.14. Catalog: APB155405791. | |
| Pemetrexed Impurity 6 | An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C24H30N6O8. Mole weight: 530.54. | |
| Pemetrexed Impurity 7 | Pemetrexed Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H26N4O5. Mole Weight: 498.54. Catalog: APB10800. | |
| Pemetrexed Impurity 7 (Mixture of Diastereomers) | Pemetrexed Impurity 7 (mixture of diastereomers) is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed 6-oxo diacid impurity; (2S)-2-[[4-[2-(2-amino-4,6-dioxo-5,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid. Grades: ≥ 95%. CAS No. 193281-00-4. Molecular formula: C20H21N5O7. Mole weight: 443.41. | |
| Pemetrexed Impurity 8 | Pemetrexed Impurity 8 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Benzoic acid, 4-(3-bromo-4-oxobutyl)-, methyl ester; SCHEMBL1447122; 2-bromo-4-(4-carbomethoxyphenyl)butanal. Grades: > 98%. CAS No. 155405-79-1. Molecular formula: C12H13BrO3. Mole weight: 285.13. | |
| Pemetrexed Impurity 8 | Pemetrexed Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S)-2-(4-(2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid. CAS No. 193281-00-4. Molecular Formula: C20H21N5O7. Mole Weight: 443.41. Catalog: APB193281004. | |
| Pemetrexed Impurity 8 | Pemetrexed Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1320346-43-7. Molecular Formula: C16H16N4O4. Mole Weight: 328.33. Catalog: APB1320346437. | |
| Pemetrexed Impurity 9 | Pemetrexed Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C30H26N8O5. Mole Weight: 578.59. Catalog: APB10802. | |
| Pemetrexed Impurity A | Cas No. 137281-39-1. | |
| Pemetrexed Impurity B | An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed (5R)-Dimer ; (2S)-2,2'-[[(5R)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82. | |
| Pemetrexed Impurity C | An impurity of Pemetrexed which is a chemotherapy drug used to treat non small cell lung cancer and pleural mesothelioma. Synonyms: Pemetrexed (5S)-Dimer ; (2S)-2,2'-[[(5S)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82. | |
| Pemetrexed Impurity D | An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. CAS No. 144051-68-3. Molecular formula: C25H28N6O9. Mole weight: 556.54. | |
| Pemetrexed Impurity E Disodium Salt | An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Synonyms: (2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid sodium. Grades: >95%. CAS No. 937370-10-0. Molecular formula: C20H19N5Na2O6. Mole weight: 471.38. | |
| Pemetrexed Impurity-R | An impurity of Pemetrexed which belongs to a class of chemotherapeutic drugs known as folate antimetabolites. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42. | |
| Pemetrexed Impurity-S | An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42. | |
| Pemetrexed L-Glutamic Acid Benzyl Dimethyl Triester | Pemetrexed L-glutamic acid benzyl dimethyl triester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Benzyl Dimethyl Triester. Molecular formula: C34H38N6O9. Mole weight: 674.70. | |
| Pemetrexed L-Glutamic Acid Benzyl Dimethyl Triester | Protected Pemetrexed L-Glutamic acid (P219530), an impurity of Pemetrexed (P219500). Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Benzyl Dimethyl Triester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed L-Glutamic Acid Trisodium | An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed L-Glutamic Acid Trisodium Salt; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Sodium Salt; Pemetrexed Impurity D. Grades: > 95%. CAS No. 1265908-59-5. Molecular formula: C25H25N6O9.3Na. Mole weight: 622.48. | |
| Pemetrexed L-Glutamyl-L-glutamic Acid | Pemetrexed L-Glutamyl-L-glutamic Acid is used in the synthesis of Pemetrexed, which is a chemotherapy medication for the treatment of pleural mesothelioma and non-small cell lung cancer (NSCLC). Synonyms: Pemetrexed α-Dipeptide Impurity; Pemetrexed Impurity 22; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-α-glutamyl-; N-{4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-α-glutamyl-L-glutamic acid. Grades: ≥95%. CAS No. 883553-87-5. Molecular formula: C25H28N6O9. Mole weight: 556.52. | |
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