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| Product | Description | |
|---|---|---|
| Pembrolizumab | Pembrolizumab (MK-3475) is a humanized IgG4 antibody inhibiting the programmed cell death 1 ( PD-1 ) receptor, used in cancer immunotherapy. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MK-3475; Lambrolizumab. CAS No. 1374853-91-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9902. |  |
| Pemetrexed | N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]L-Glutamic acid. CAS No. 137281-23-3. Product ID: 8-04400. Molecular formula: C20H21N5O6. Mole weight: 427.42. Purity: 0.99. |  |
| Pemetrexed | Pemetrexed. CAS No. 150399-23-8. Product ID: 8-04228. Molecular formula: C20H19N5O6Na2. Mole weight: 471.38. | |
| Pemetrexed | Pemetrexed (LY231514) is an antifolate , the K i values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase ( TS ), dihydrofolate reductase ( DHFR ), and glycinamide ribonucleotide formyltransferase ( GARFT ), respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY231514. CAS No. 137281-23-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10820. | |
| Pemetrexed | Pemetrexed. Group: Biochemicals. Grades: Highly Purified. CAS No. 137281-23-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H21N5O6. US Biological Life Sciences. |  Worldwide |
| Pemetrexed-1-methyl Ester | Pemetrexed-1-methyl ester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed-1-methyl Ester; Pemetrexed Monomethyl Ester 1; SCHEMBL14331358; 1265908-61-9; (4R)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate; Pemetrexed Impurity 1; 1265908-63-1. Grades: 98%. CAS No. 1265908-63-1. Molecular formula: C21H23N5O6. Mole weight: 441.44. |  |
| Pemetrexed-5-methyl Ester | Pemetrexed-5-methyl ester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Monomethyl Ester 2; 1265908-60-8; (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-5-methoxy-5-oxopentanoic acid; SCHEMBL15078817; (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid ; Pemetrexed Impurity 2; 1265908-64-2. Grades: 98%. CAS No. 1265908-64-2. Molecular formula: C21H23N5O6. Mole weight: 441.44. | |
| Pemetrexed acid oxo impurity | An impurity of Pemetrexed which was approved by the United States Food and Drug administration in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Synonyms: 4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid. Grades: > 95%. CAS No. 193265-47-3. Molecular formula: C15H14N4O4. Mole weight: 314.3. | |
| Pemetrexed Alpha-Hydroxy Lactum Isomer II | Pemetrexed alpha-hydroxy lactum isomer II is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (2R)-2-(4-(2-(2-Amino-5-hydroxy-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic Acid. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed-d5 Diethyl Ester | Isotope labelled Pemetrexed-d5 Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: Diethyl 2- (4- (2- (2-Amino-4-oxo-4, 7-dihydro-3H-pyrrolo[2, 3-d]pyrimidin-5-yl) ethyl) benzamido) pentanedioate-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed-d5, Disodium Salt (N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid-d5 Disodium Salt) | Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid-d5 Disodium Salt. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Pemetrexed Diethyl Ester | Pemetrexed Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: Diethyl 2- (4- (2- (2-Amino-4-oxo-4, 7-dihydro-3H-pyrrolo[2, 3-d]pyrimidin-5-yl) ethyl) benzamido) pentanedioate. Grades: Highly Purified. CAS No. 146943-43-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed Diethyl Ester | Pemetrexed diethyl ester is one of pemetrexed intermediates. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Diethyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate; (S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester. Grades: ≥95%. CAS No. 146943-43-3. Molecular formula: C24H29N5O6. Mole weight: 483.52. | |
| Pemetrexed Dimer Impurity 1 | Pemetrexed Dimer Impurity 1 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C43H46N10O15. Mole weight: 942.88. | |
| Pemetrexed disodium | Pemetrexed disodium. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid sodium salt. Grades: Highly Purified. CAS No. 150399-23-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C20H19N5Na2O6. US Biological Life Sciences. | Worldwide |
| Pemetrexed disodium | Pemetrexed disodium. CAS No. 150399-23-8. Product ID: 8-04493. Molecular formula: C20H19N5O6Na2. Mole weight: 471.38. Source : natural proteasome inhibitor anti-cancer agent. | |
| Pemetrexed disodium | Pemetrexed disodium (LY231514 disodium) is an antifolate, the K i s of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY231514 disodium. CAS No. 150399-23-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-10820A. | |
| Pemetrexed Disodium | Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Synonyms: LY231514 disodium; Alimta; Rolazar; Tifolar; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2); L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt; LY-231514 disodium; LY 231514 disodium; Pemetrexed sodium; sodium (4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate. Grades: >98%. CAS No. 150399-23-8. Molecular formula: C20H19N5Na2O6. Mole weight: 471.37. | |
| Pemetrexed Disodium | Pemetrexed Disodium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 150399-23-8. Molecular formula: C20H19N5Na2O6. Mole weight: 471.38. Catalog: APB150399238. |  |
| Pemetrexed disodium heptahydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardschiral moleculesenzyme activators, inhibitors & substrateseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Pemetrexed disodium heptahydrate, L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate (9CI), Disodium (2S)-2-[[4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate heptahydrate,L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt, hydrate (1:2:7). | |
| Pemetrexed disodium heptahydrate | Pemetrexed disodium heptahydrate is a novel antifolate , the K i values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase ( TS ), dihydrofolate reductase ( DHFR ), and glycinamide ribonucleotide formyltransferase ( GARFT ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY231514 disodium heptahydrate. CAS No. 357166-29-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10820B. | |
| Pemetrexed Disodium Heptahydrate | Pemetrexed Disodium Heptahydrate. Group: Biochemicals. Alternative Names: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt Heptahydrate. Grades: Highly Purified. CAS No. 357166-29-1. Pack Sizes: 10mg. Molecular Formula: C20H33N5Na2O13, Molecular Weight: 597.48. US Biological Life Sciences. | Worldwide |
| Pemetrexed Disodium Heptahydrate | Pemetrexed disodium is an chemotherapy drug identified as a highly efficient substrate for folylpolyglutamate synthase, potently inhibits multiple folate-dependent enzymes involved in both purine and pyrimidine synthesis including thymidylate synthase (Ki = 109 nM). Uses: A novel antifolate and antimetabolite for ts, dhfr and garft with ki of 1.3 nm, 7.2 nm and 65 nm, respectively. Synonyms: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt Heptahydrate; Pemetrexed (sodium salt hydrate); L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-8 oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. Grades: > 98%. CAS No. 357166-29-1. Molecular formula: C20H33N5Na2O13. Mole weight: 597.48. | |
| Pemetrexed Disodium Hydrate | Pemetrexed Disodium Hydrate. Group: Biochemicals. Alternative Names: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-Glutamic Acid Disodium Hydrate. Grades: Highly Purified. CAS No. 357166-30-4. Pack Sizes: 10mg. Molecular Formula: C20H19Na2N5O6 5/2 H2O, Molecular Weight: 471.37. US Biological Life Sciences. | Worldwide |
| Pemetrexed disodium salt | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C20H19N5Na2O6. CAS No. 150399-23-8. Prepack ID 23048138-1g. Molecular Weight 471.37. See USA prepack pricing. |  |
| Pemetrexed, Disodium Salt, Heptahydrate (N-[4-[(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium, LY-231514, Alimta) | Pemetrexed inhibits dihydrofolate reductase, thymidylate synthase and glycinamide ribonucleotide formyltransferase with Ki values of 7nM, 109nM and 9.3uM, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 357166-29-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed EP Impurity B | Pemetrexed EP Impurity B is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (R)-Pemetrexed EP Isomer; (2S, 2'S)-2, 2'- ( (4, 4'- ( ( (R)-2, 2'-Diamino-4, 4', 6-trioxo-4, 4', 5, 6, 7, 7'-hexahydro-1H, 1'H-[5, 6'-bipyrrolo[2, 3-d]pyrimidine]-5, 5'-diyl)bis (ethane-2, 1-diyl))bis (benzoyl))bis (azanediyl))dipentanedioic Acid. Grades: > 98%. CAS No. 1802552-04-0. Molecular formula: C40H40N10O13. Mole weight: 868.80. | |
| Pemetrexed Impurity | Cas No. 204257-65-8. | |
| Pemetrexed Impurity 19 | Pemetrexed Impurity 19 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C25H28N6O9. Mole weight: 556.52. | |
| Pemetrexed Impurity 25 | Pemetrexed Impurity 25 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C8H10N4O4. Mole weight: 226.19. | |
| Pemetrexed Impurity 26 | Pemetrexed Impurity 26 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C14H15N5O3. Mole weight: 301.30. | |
| Pemetrexed Impurity 27 | Pemetrexed Impurity 27 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C15H15N5O4. Mole weight: 329.31. | |
| Pemetrexed Impurity 28 | Pemetrexed Impurity 28 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Impurity 24. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 29 | Pemetrexed Impurity 29 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 3 | An impurity of Pemetrexed which binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Grades: > 95%. CAS No. 229470-22-8. Molecular formula: C17H21N5O5. Mole weight: 375.39. | |
| Pemetrexed Impurity 3 | Pemetrexed Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123910-88-3. Molecular formula: C12H16O3. Mole weight: 208.26. Catalog: APB123910883. | |
| Pemetrexed Impurity 30 | Pemetrexed Impurity 30 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C31H40N6O9. Mole weight: 640.68. | |
| Pemetrexed Impurity 31 | Pemetrexed Impurity 31 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C27H34N6O6. Mole weight: 538.59. | |
| Pemetrexed Impurity 32 | Pemetrexed Impurity 32 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 33 | Pemetrexed Impurity 33 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. CAS No. 1417656-72-4. Molecular formula: C20H23N5O9. Mole weight: 477.42. | |
| Pemetrexed Impurity 34 | Pemetrexed Impurity 34 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H23N5O9. Mole weight: 477.42. | |
| Pemetrexed Impurity 35 | Pemetrexed Impurity 35 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H23N5O9. Mole weight: 477.42. | |
| Pemetrexed Impurity 36 | Pemetrexed Impurity 36 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
| Pemetrexed Impurity 37 | Pemetrexed Impurity 37 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: 3-(4-carboxyphenyl)-propionaldehyde ethyl ester; 4-(3-oxopropyl)benzoic acid ethyl ester; 4-ethoxycarbonylhydrocinnamal; 3-(4-carbethoxyphenyl)propanal. Grades: ≥ 95%. CAS No. 151864-81-2. Molecular formula: C12H14O3. Mole weight: 206.24. | |
| Pemetrexed Impurity 38 | Pemetrexed Impurity 38 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C12H12O4. Mole weight: 220.22. | |
| Pemetrexed Impurity 4 | An impurity of Pemetrexed which is a chemotherapy drug. Grades: > 95%. Molecular formula: C15H17N5O5. Mole weight: 347.33. | |
| Pemetrexed Impurity 5 | An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C24H32N6O8. Mole weight: 532.56. | |
| Pemetrexed Impurity 6 | An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C24H30N6O8. Mole weight: 530.54. | |
| Pemetrexed Impurity 7 (Mixture of Diastereomers) | Pemetrexed Impurity 7 (mixture of diastereomers) is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed 6-oxo diacid impurity; (2S)-2-[[4-[2-(2-amino-4,6-dioxo-5,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid. Grades: ≥ 95%. CAS No. 193281-00-4. Molecular formula: C20H21N5O7. Mole weight: 443.41. | |
| Pemetrexed Impurity 8 | Pemetrexed Impurity 8 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Benzoic acid, 4-(3-bromo-4-oxobutyl)-, methyl ester; SCHEMBL1447122; 2-bromo-4-(4-carbomethoxyphenyl)butanal. Grades: > 98%. CAS No. 155405-79-1. Molecular formula: C12H13BrO3. Mole weight: 285.13. | |
| Pemetrexed Impurity 8 | Pemetrexed Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1320346-43-7. Molecular formula: C16H16N4O4. Mole weight: 328.33. Catalog: APB1320346437. | |
| Pemetrexed Impurity A | Cas No. 137281-39-1. | |
| Pemetrexed Impurity B | An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed (5R)-Dimer ; (2S)-2,2'-[[(5R)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82. | |
| Pemetrexed Impurity C | An impurity of Pemetrexed which is a chemotherapy drug used to treat non small cell lung cancer and pleural mesothelioma. Synonyms: Pemetrexed (5S)-Dimer ; (2S)-2,2'-[[(5S)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82. | |
| Pemetrexed Impurity D | An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. CAS No. 144051-68-3. Molecular formula: C25H28N6O9. Mole weight: 556.54. | |
| Pemetrexed Impurity E Disodium Salt | An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Synonyms: (2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid sodium. Grades: >95%. CAS No. 937370-10-0. Molecular formula: C20H19N5Na2O6. Mole weight: 471.38. | |
| Pemetrexed Impurity-R | An impurity of Pemetrexed which belongs to a class of chemotherapeutic drugs known as folate antimetabolites. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42. | |
| Pemetrexed Impurity-S | An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42. | |
| Pemetrexed L-Glutamic Acid Benzyl Dimethyl Triester | Pemetrexed L-glutamic acid benzyl dimethyl triester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Benzyl Dimethyl Triester. Molecular formula: C34H38N6O9. Mole weight: 674.70. | |
| Pemetrexed L-Glutamic Acid Benzyl Dimethyl Triester | Protected Pemetrexed L-Glutamic acid (P219530), an impurity of Pemetrexed (P219500). Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Benzyl Dimethyl Triester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed L-Glutamic Acid Trisodium | An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed L-Glutamic Acid Trisodium Salt; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic Acid Sodium Salt; Pemetrexed Impurity D. Grades: > 95%. CAS No. 1265908-59-5. Molecular formula: C25H25N6O9.3Na. Mole weight: 622.48. | |
| Pemetrexed L-Glutamyl-L-glutamic Acid | Pemetrexed L-Glutamyl-L-glutamic Acid is used in the synthesis of Pemetrexed, which is a chemotherapy medication for the treatment of pleural mesothelioma and non-small cell lung cancer (NSCLC). Synonyms: Pemetrexed α-Dipeptide Impurity; Pemetrexed Impurity 22; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-α-glutamyl-; N-{4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-α-glutamyl-L-glutamic acid. Grades: ≥95%. CAS No. 883553-87-5. Molecular formula: C25H28N6O9. Mole weight: 556.52. | |
| Pemetrexed Methyl Ester | Protected Pemetrexed. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Ester. Grades: Highly Purified. CAS No. 155405-81-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Pemetrexed Methyl Ester | An impurity of Pemetrexed which is a chemotherapy drug used to treat non small cell lung cancer and pleural mesothelioma. Synonyms: Pemetrexed Methyl Ester; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Ester. Grades: > 95%. CAS No. 155405-81-5. Molecular formula: C22H25N5O6. Mole weight: 455.47. | |
| Pemetrexed Monomethyl Ester Impurity 1 | An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Synonyms: sodium (4R)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5- yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate. Grades: > 95%. CAS No. 1265908-61-9. Molecular formula: C21H22N5O6.Na. Mole weight: 463.43. | |
| Pemetrexed Monomethyl Ester Impurity 2 | An impurity of Pemetrexed which is an antifolate, a substance that blocks the activity of folic acid. Synonyms: Pemetrexed Monomethyl Ester 2; 1265908-60-8; (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-5-methoxy-5-oxopentanoic acid; SCHEMBL15078817; (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid ; Pemetrexed Impurity 2; 1265908-64-2. Grades: > 95%. CAS No. 1265908-60-8. Molecular formula: C21H22N5O6.Na. Mole weight: 463.43. | |
| Pemetrexed ph Euro impurity B + C Mixture (1:1) | | |
| Pemetrexed Related Impurity 1 | An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C25H28N6O9. Mole weight: 556.54. | |
| Pemetrexed Related Impurity 2 | An impurity of Pemetrexed which is an antifolate, a substance that blocks the activity of folic acid. Grades: > 95%. Molecular formula: C20H21N5O8. Mole weight: 459.42. | |
| Pemetrexed Tromethamine Amide | Pemetrexed tromethamine amide is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-tert-Butyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoate. Molecular formula: C28H38N6O8. Mole weight: 586.64. | |
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