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| Product | Description | |
|---|---|---|
| Peucedanol | Peucedanol. Group: Biochemicals. Alternative Names: Ohter Cas No, 20126-72-1. Grades: Plant Grade. CAS No. 20516-23-8. Pack Sizes: 10mg. Molecular Formula: C14H16O5, Molecular Weight: 264.274. US Biological Life Sciences. |  Worldwide |
| Pevonedistat | Pevonedistat Inhibitor. Uses: Scientific use. Product Category: T6332. CAS No. 905579-51-3. |  |
| Pevonedistat | Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme ( NAE ) inhibitor with an IC 50 of 4.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN4924. CAS No. 905579-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-70062. |  |
| Pevonedistat hydrochloride | Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC 50 of 4.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN4924 hydrochloride. CAS No. 1160295-21-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10484. | |
| PE wax | PE wax. Group: Polymers. |  |
| Pexacerfont | Pexacerfont is a selective corticotropin-releasing factor ( CRF 1 ) receptor antagonist with IC 50 of 6.1±0.6 nM for human CRF 1 receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-562086. CAS No. 459856-18-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12127. | |
| Pexidartinib | Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC 50 s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX-3397. CAS No. 1029044-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749. | |
| Pexidartinib | Pexidartinib Inhibitor. Uses: Scientific use. Product Category: T2115. CAS No. 1029044-16-3. | |
| Pexidartinib hydrochloride | Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC 50 s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX-3397 hydrochloride. CAS No. 2040295-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749A. | |
| Pexiganan | An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Grade: >95%. CAS No. 147664-63-9. Molecular formula: C122H209N31O23. Mole weight: 2478.19. |  |
| Pexiganan | Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections [1]. Uses: Scientific research. Group: Peptides. Alternative Names: MSI 78 free base. CAS No. 147664-63-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105088. | |
| Pexiganan acetate | An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Synonyms: MSI 78; Pexiganan. Grade: >98%. CAS No. 172820-23-4. Molecular formula: C122H210N32O22.C2H4O2. Mole weight: 2537.22. | |
| Pexmetinib | Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38? and p38?, respectively, and can be used in the research of acute myeloid leukemia. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-614. CAS No. 945614-12-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16782. | |
| PF-00356231 hydrochloride | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 ( IC 50 =1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC 50 s of 0.00065, 1.7, 0.98, 0.39 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 820223-77-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114091. | |
| PF-00446687 free base | PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12?±?1 nM[1]. Pf-446687 is brain penetrant[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 862281-92-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10622. | |
| PF-01247324 | PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker with an IC50 of 196 nM for recombinant human Nav1.8 channel. Uses: Scientific research. Group: Signaling pathways. CAS No. 875051-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101383. | |
| PF-01247324 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PF-02413873 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03049423 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03084014 hydrobromide | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03246799 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03463275 | PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a K i of 11.6 nM. PF-03463275 has the potential for Schizophrenia research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173239-39-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10716A. | |
| PF-03549184 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03654746 Tosylate | PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms [1]. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1039399-17-1. Pack Sizes: 1 mg. Product ID: HY-11044. | |
| PF 03716556 | PF 03716556 is a potent, selective, competitive and reversible acid pump (H + ,K + -ATPase) antagonist with pIC 50 s of 6.026, 6.038 and 6.009 for porcine , canine , and human recombinant gastric H + ,K + -ATPase , respectively. PF 03716556 is inactive against other receptors, ion channels, and enzymes. PF 03716556 has the potential for gastroesophageal reflux disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 928774-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13100. | |
| PF-03716556 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03732010 | PF-03732010 is a humanized antibody expressed in CHO, targeting CDH3/P-cadherin. PF-03732010 has a huIgG1 type heavy chain and a huλ type light chain, with a predicted molecular weight (MW) of 142.7 kDa. The isotype control for PF-03732010 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2070913-84-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990645. | |
| PF 03814735 | PF 03814735 is an orally bioavailable small molecule aurora kinase inhibitor that plays a key role in the regulation of mitosis. PF 03814735 is a anticancer agent used for cancer therapy. Group: Biochemicals. Alternative Names: N-[2-[(1S,4R)-6-[[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]-acetamide. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PF-03814735 | PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 942487-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14574. | |
| PF-03814735 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF 03814735 (Aurora Kinases A and B, N-[2-[(1S,4R)-6-[[4-(Cyclobutylamin o)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3, 4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]- acetamide) | ATP-competitive inhibitor of Aurora kinases A and B (IC50 values are 0.8 and 5nm for recombinant Aurora B and Aurora A, respectively). Inhibits phosphorylation of Aurora B, histone H3 and Aurora A in cultured MDA-MB-231 cells (IC50 values are ~20, 50 and 150nm respectively). Shown to block cytokinesis; inhibits cellular proliferation in several human tumor cell lines, including HCT-116, HL-60, A549 and H125, and in human xenograft mouse models. Orally available. Group: Biochemicals. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-04217329 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04217903 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04217903 | PF-04217903 is a potent ATP-competitive c-Met kinase inhibitor with K i of 4.8 nM for human c-Met. PF-04217903 shows more than 1,000-fold selectivity relative to 208 kinases. Antiangiogenic properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956905-27-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12017. | |
| PF-04217903 mesylate | PF-04217903 mesylate is a potent ATP-competitive c-Met kinase inhibitor with K i of 4.8 nM for human c-Met. PF-04217903 mesylate shows more than 1,000-fold selectivity relative to 208 kinases. Antiangiogenic properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956906-93-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12017A. | |
| PF-04363467 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF 04418948 | PF 04418948 acts as a novel, potent and selective prostoglandin EP2 receptor antagonist. Group: Biochemicals. Alternative Names: (1-(-fluorbenzoyl)-3-{[(6-methoxy-2-napthyl)oxy]methyl} Azetidine-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-04418948 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04418948 | PF-04418948 is an orally active, potent and selective prostaglandin EP 2 receptor antagonist with an IC 50 of 16 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1078166-57-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-18966. | |
| PF-04445597 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04447943 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04449613 | PF-04449613 is a selective PDE9A inhibitor with an IC50 of 22 nM[1]. PF-04449613 improved motor learning ability in a mouse model[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1236858-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12788. | |
| PF-04449613 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04449913 maleate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04455242 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04457845 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04471141 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04479745 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04531083 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04620110 | PF-04620110 is a potent, selective and orally bioavailable diglyceride acyltransferase-1 (DGAT-1) inhibitor with an IC 50 of 19 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1109276-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13009. | |
| PF-04620110 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04634817 succinate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04671536 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04691502 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04691502 | PF-04691502 is a potent and selective inhibitor of PI3K and mTOR. PF-04691502 binds to human PI3Kα, β, δ, γ and mTOR with K i s of 1.8, 2.1, 1.6, 1.9 and 16 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1013101-36-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15177. | |
| PF 04691502 (2-Amino-8-[trans-4-(2-hydroxyethoxy )cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-py rido[2,3-d]pyrimidin-7(8H)-one) | Potent and selective dual ATP-competitive PI 3-K/mTOR inhibitor (Ki values are 1.6, 1.8, 1.9, 2.1 and 16nm for human PI 3-K delta, alpha, gamma, beta, and mTOR, respectively). Displays no significant inhibitory activity at more than 80 protein kinases (concentration ≥ 10um) including hVps34, PI 3-K downstream kinases, and MAPK family members. Orally available. Induces robust cell cycle arrest at the G1 phase in U87MG cancer cells and antitumor activity in SKOV3 ovarian cancer xenograft models. Group: Biochemicals. Grades: Highly Purified. CAS No. 1013101-36-4. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| PF-04701475 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04725379 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04753299 | ?98%. Group: Fluorescence/luminescence spectroscopy. | |
| PF-04802367 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04802367 | PF-04802367 (PF-367) is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3? enzyme assay and 1.1 nM based on ADP-Glo assay. PF-04802367 shows desirable central nervous system (CNS) properties and potency. PF-04802367 is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3? and GSK-3?) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-367. CAS No. 1962178-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122026. | |
| PF-04827736 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04856264 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04859989 | PF-04859989 Inhibitor. Uses: Scientific use. Product Category: T28368. CAS No. 177943-33-8. | |
| PF-04859989 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04859989 hydrochloride | PF-04859989 hydrochloride is a brain-penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC 50 s of 23 and 263 nM for hKAT II and rKAT II. PF-04859989 hydrochloride is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 μM, respectively) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 177943-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116451. | |
| PF-04880594 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04885614 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-04957325 | PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1305115-80-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15426. | |
| PF-04979064 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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