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| Product | Description | |
|---|---|---|
| PF-04995274 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PF-05020182 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-05085727 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF 05089771 | PF 05089771 is a potent, orally active and selective arylsulfonamide Na v 1.7 inhibitor, with IC 50 values of 11 nM, 12 nM, 13 nM, 171 nM and 8 nM for hNa v 1.7, cynNa v 1.7, dogNa v 1.7, ratNa v 1.7, and musNa v 1.7, respectively. PF 05089771 is under the study for pain and diabetic neuropathy [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1235403-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12883. |  |
| PF-05089771 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-05105679 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-05175157 | PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1301214-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12942. | |
| PF-05175157 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-05180999 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-05180999 | PF-05180999 (PF-999) is a phosphodiesterase 2A (PDE2A) inhibitor, with an IC 50 of 1.6 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-999. CAS No. 1394033-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111371. | |
| PF-05212384 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF 05212384 (PKI-587) (N-[4-[[4-(Dimethylamino)-1-piperidi nyl]carbonyl]phenyl]-N'-[4-(4,6-di-4-morpholinyl-1, 3,5-triazin-2-yl)phenyl]urea) | Potent and selective dual inhibitor of PI 3-kinase/mTOR (IC50 values are 0.4, 1.6 and 5.4nm for PI 3-Kalpha, mTOR and PI 3-Kgamma respectively). Exhibits selectivity over 234 other protein kinases (IC50 >10um). Potently inhibits tumor cell growth in 37 different tumor cell lines (IC50 < 100nm). Also exhibits antitumor activity in MDA-361, HCT-116, H1975 and U87MG xenograft models. Group: Biochemicals. Grades: Highly Purified. CAS No. 1197160-78-3. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| PF-05221304 | PF-05221304 Inhibitor. Uses: Scientific use. Product Category: T9209. CAS No. 1370448-25-1. |  |
| PF-05236216 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-05274857 Hydrochloride | PF-05274857 Hydrochloride. Group: Biochemicals. Alternative Names: 1-(4-(5'-Chloro-3,5-dimethyl-[2,4'-bipyridin]-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one Monohydrochloride. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C20H26Cl2N4O3S, Molecular Weight: 473.42. US Biological Life Sciences. | Worldwide |
| PF-05883083-00 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06250112 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06260933 | PF-06260933 is an orally active and highly selective inhibitor of MAP4K4 with IC50s of 3.7 and 160 nM for kinase and cell, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1811510-56-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19562. | |
| PF-06260933 dihydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06263276 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06273340 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06281355 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06282999 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06282999 | PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1435467-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19321. | |
| PF-06284674 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06297470 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06305591 dihydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06372865 | PF-06372865 is an orally active, α2/α3/α5 subtype-selective GABA A positive allosteric modulator (PAM). PF-06372865 is a high affinity ligand at GABA A receptors containing α1/α2/α3/α5 subunits ( K i s of 2.9 nM, 21 nM, 134 nM for α2, α1 PAM, α2 PAM, respectively), with low affinity for α4/α6 subunits. PF-06372865 can across the blood-brain barrier (BBB). PF-06372865 has anxiolytic activity and has the potential for epilepsy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1614245-70-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120874. | |
| PF-06380101 | PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs. Uses: Adcs cytotoxin. Synonyms: PF-06380101; PF 06380101; PF06380101; Auristatin 0101; AUR-0101; AUR 0101; AUR0101. Grade: >98%. CAS No. 1436391-86-4. Molecular formula: C39H62N6O6S. Mole weight: 743.01. |  |
| PF-06409577 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06409577 | PF-06409577 is a potent and selective allosteric activator of AMPK ?1?1?1 isoform with an EC50 of 7 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1467057-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103683. | |
| PF-06422913 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06424439 | PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM[1]. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1469284-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-108341. | |
| PF-06424439 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06424439 methanesulfonate | PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM[1]. PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1469284-79-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108341A. | |
| PF-06439015 methanesulfonate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06442609 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06446846 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06446846 hydrochloride | PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1632250-50-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120088A. | |
| PF-06447475 | PF-06447475 is a highly potent, selective and brain penetrant LRRK2 inhibitor with an IC50 of 3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1527473-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12477. | |
| PF-06456384 trihydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06456384 trihydrochloride | PF-06456384 trihydrochloride is a highly potent and selective NaV1.7 inhibitor with an IC50 of 0.01 nM. PF-06456384 trihydrochloride has the potential for formalin pain model research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1834610-75-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118952A. | |
| PF-06459988 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06462894 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06463922 acetate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06465469 | PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2?nM. PF-06465469 also inhibits BTK. PF-06465469 inhibits cell migration in response to CXCL12. PF-06465469 decreases PD-1 and LAG-3 expression. PF-06465469 can be used to study leukemia and T-cell lymphoma[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1407966-77-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108691. | |
| PF-06465469 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06648671 | PF-06648671 is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1587727-31-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120789. | |
| PF-06649283 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF06650833 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06651385 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06651481-00 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06651600 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06658607 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06658959-00 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06663181-00 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06663195 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06663827-00 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06663829-00 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06665105-00 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06672131 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06683324 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF06691283 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06700841 tosylate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06726304 | PF-06726304 is a potent and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 with K i s of 0.7 and 3.0 nM, respectively. PF-06726304 displays robust antitumor growth activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1616287-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103682. | |
| PF-06726304 acetate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06733804 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06737007 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06745013 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-06745268 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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