A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PHA-543613 is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a K i of 8.8 nM. PHA-543613 displays selectivity for α7-nAChR over α3β4, α1β1γδ, α4β2 and 5-HT3 receptors [1]. PHA-543613 can be used for the cognitive deficits of Alzheimer's disease and schizophrenia research [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478149-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105670.
PHA-543613 Dihydrochloride
PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer?s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays. Group: Biochemicals. Alternative Names: N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide Dihydrochloride;PHA 543613E. Grades: Highly Purified. CAS No. 478148-58-2. Pack Sizes: 10mg. US Biological Life Sciences.
A potent agonist highly selective for alpha7 nicotinic acetylcholine receptor (alpha7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of alpha7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 478149-53-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PHA 568487
Selective α7 nAChR agonist. Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3 β4 and α1 β1δγ respectively, and % inhibition is < 1 and 5% for α4 β2 and hERG respectively). Orally active and brain penetrant. Group: Biochemicals. Alternative Names: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide Fumarate. Grades: Highly Purified. CAS No. 527680-57-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?O?, Molecular Weight: 404.41. US Biological Life Sciences.
Worldwide
PHA 568487 free base
PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor ( α-7 nAchR ) agonist. PHA 568487 free base reduces neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 527680-56-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129674.
PHA-665752
PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met kinase ( K i=4 nM; IC 50=9 nM). PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 477575-56-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11107.
PHA-665752 ia a c-Met kinase inhibitor. PHA-665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases. Group: Biochemicals. Alternative Names: (3Z) -5-[[ (2, 6-dichlorophenyl) methyl]sulfonyl]-3-[[3, 5-dimethyl-4-[[ (2R) -2- (1-pyrrolidinylmethyl) -1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1, 3-dihydro-2H-indol-2-one Hydrate; PHA 665752 Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PHA-767491
PHA-767491 is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAY10572. CAS No. 845714-00-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13461.
PHA 767491 Dihydrochloride Salt
A potent and selective ATP-competitive dual inhibitor cdc7/cdk9. It blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites. Inhibits cell proliferation in a variety of human cell lines and induces apoptosis in a p53-independent manner in vivo. Also inhibits mitogen-activated protein kinase-activated protein kinase-2 (MK-2). Group: Biochemicals. Alternative Names: 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one Dihydrochloride;PHA 767491 Dihydrochloride Salt; PF-02334471. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
PHA 767491 hydrochloride
PHA 767491 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 942425-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
PHA-767491 hydrochloride is a dual Cdc7/Cdk9 inhibitor, with IC50s of 10 nM and 34 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAY-10572 hydrochloride. CAS No. 942425-68-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13461A.
PHA-793887
PHA-793887 is a potent, ATP-competitive CDK inhibitor, can inhibit Cdk2, Cdk1, Cdk4, and Cdk9 with IC50s of 8 nM, 60 nM, 62 nM and 138 nM, respectively, and also inhibits glycogen synthase kinase 3? with an IC50 of 79 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 718630-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11001.
Phaclofen is a selective GABA B receptor antagonist. Phaclofen is a peripheral and central baclofen antagonist. Phaclofen maybe a potential compound in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 114012-12-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100798.
Phaclofen
Phaclofen. Group: Biochemicals. Grades: Purified. CAS No. 114012-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Phacolysine sodium salt
Phacolysine sodium salt. Group: Biochemicals. Alternative Names: 5,12-Dihydroquinoxalino[2,3-b]phenazine-2,9-disulfonic acid sodium salt; Jing ming; Phacolin. Grades: Highly Purified. CAS No. 3863-80-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C18H10N4Na2O6S2. US Biological Life Sciences.
Worldwide
Phallacidin
Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin [1]. Uses: Scientific research. Group: Peptides. CAS No. 26645-35-2. Pack Sizes: 1 mg. Product ID: HY-P2031.
Phalloidin
Phalloidin. Group: Biochemicals. Grades: Purified. CAS No. 17466-45-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Phalloidin
Phalloidin, a heptapeptide phallotoxin produced by Amanita phalloides, the death cap mushroom, is an F-actin stabilizing toxin and aids cytoskeletal deorganization in WPMY-1 cells. It decreases dissociation rate constant for actin subunits from filament ends and lowers critical concentration for polymerization. Synonyms: Cyclo[L-alanyl-D-threonyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-(4R)-4,5-dihydroxy-L-leucyl] Cyclic (3→6)-thioether; 18,9-(Iminoethaniminoethaniminoethaniminomethano)-17H-pyrrolo[1',2':5,6][1,5,8,11]thiatriazacyclopentadecino[15,14-b]indole Cyclic Peptide Derivative; NSC 523214; NSC-523214; NSC523214. CAS No. 17466-45-4. Molecular formula: C35H48N8O11S. Mole weight: 788.87.
Phalloidin
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome [1]. Uses: Scientific research. Group: Peptides. CAS No. 17466-45-4. Pack Sizes: 1 mg. Product ID: HY-P0028.
Phalloidin-Atto 425
suitable for fluorescence, ?95.0% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 430LS
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 488
BioReagent, suitable for fluorescence, ?90% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 490LS
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 514
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 520
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 565
suitable for fluorescence, ?80% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 594
suitable for fluorescence, ?90% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 655
suitable for fluorescence, ?95.0% (sum of isomers, HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 665
suitable for fluorescence, ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 700
suitable for fluorescence, ?80.0% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 725
suitable for fluorescence, ?80% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 740
suitable for fluorescence, BioReagent. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-FITC
Phalloidin-FITC is fluorophore-labeled phalloidin used for visualizing the actin cytoskeleton. Synonyms: FITC-bicyclic(Ala-DThr-Cys-cis-4-hydroxy-Pro-Ala-2-mercapto-Trp-5-amino-4-hydroxy-Leu)(S-3→6); Cyclo(-Ala-D-Thr-Cys-cis-Hyp-Ala-Trp-(4R)-4-hydroxy-4-Me-Orn(FITC)) (Sulfide bond between Cys and indol-2-yl); 7-[(4R)-N5-[[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]-4-hydroxy-4-methyl-L-ornithine]phalloidin; ((R)-4-Hydroxy-4-methyl-Orn(FITC)7)-Phalloidin. Grade: ≥90%. CAS No. 915026-99-2. Molecular formula: C56H60N10O15S2. Mole weight: 1177.26.
Phalloidin, Fluorescein Isothiocyanate Labeled
peptide from Amanita phalloides. Group: Fluorescence/luminescence spectroscopy.
peptide from Amanita phalloides. Group: Fluorescence/luminescence spectroscopy.
Phanerosporic acid
Phanerosporic acid is a fungal secondary metabolite isolated from Phanerochaete chrysosporium. It has antibacterial and antifungal activities. Synonyms: (-)-Phanerosporic Acid; Benzoic acid, 2,4-dihydroxy-6-[(14R)-14-hydroxypentadecyl]-. Grade: ≥95%. CAS No. 124709-28-0. Molecular formula: C22H36O5. Mole weight: 380.52.
Phantolide
Phantolide. Group: Biochemicals. Alternative Names: 1-(2,3-Dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl)ethanone; 1,1,2,3,3,6-Hexamethyl-5-indanyl methyl ketone; 6-Acetyl-1,1,2,3,3,5-hexamethylindan. Grades: Highly Purified. CAS No. 15323-35-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C17H24O. US Biological Life Sciences.
Worldwide
Pharacine
Pharacine, isolated from the bacterial strain Cytophaga sp. AM13.1, is the first cyclic terephthalic acid ester from a natural source. Synonyms: 3,8,15,20-Tetraoxatricyclo[20.2.2.210,13]octacosa-10,12,22,24,25,27-hexaene-2,9,14,21-tetrone; 1,4-Butanediol-terephthaloyl Chloride Cyclic Dimer; Pharacin; PBT Cyclic Dimer; Cyclobis(1,4-butylene terephthalate); PBT Impurity 1. Grade: >95%. CAS No. 63440-93-7. Molecular formula: C24H24O8. Mole weight: 440.44.
Phaseollidin, also called 3,9-Dihydroxy-10-prenylpterocarpan, is a natural flavonoid isolated from the fruits of Phaseolus vulgaris. Phaseollidin exhibits the activity of antimicrobial. Uses: Anti-microbial. Synonyms: 3,9-Dihydroxy-10-prenylpterocarpan. Grade: >98%. CAS No. 37831-70-2. Molecular formula: C20H20O4. Mole weight: 324.4.
phaseollidin hydratase
The enzyme from Fusarium solani, which is distinct from kievitone hydratase (EC 4.2.1.95), hydrates the methylbutenyl side-chain of the isoflavonoid phytoalexin, phaseollidin. Group: Enzymes. Synonyms: phaseollidin-hydrate hydro-lyase. Enzyme Commission Number: EC 4.2.1.97. CAS No. 143597-34-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5081; phaseollidin hydratase; EC 4.2.1.97; 143597-34-6; phaseollidin-hydrate hydro-lyase. Cat No: EXWM-5081.
Phaseollin
Phaseollin is a phenolic compound found in theherbs of Erythrina addisoniae. Phaseollin shows anticarcinogenic activity which may lead to new pharmacons to be used in cancer therapy. Uses: Anticarcinogenic. Synonyms: (6bR)-6bβ,12bβ-Dihydro-3,3-dimethyl-3H,7H-furo[3,2-c:5,4-f']bis[1]benzopyran-10-ol; (6bR,12bR)-6b,12b-Dihydro-3,3-dimethyl-3H,7H-furo[3,2-c:5,4-f']bis[1]benzopyran-10-ol. Grade: >98%. CAS No. 13401-40-6. Molecular formula: C20H18O4. Mole weight: 322.4.
PHCCC
PHCCC is a Group I mGluR antagonist with an IC 50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179068-02-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100409.
A potent positive allosteric modulator selective for mGlu4 receptors (EC50 = 3uM). Also, a less potent agonist of mGlu6 receptors (EC50 = 15uM). Biologically active admitted systematically. Often used in assessing the functional roles of mGlu4 receptors or group III mGlu receptors in a variety of research areas, such as epileptic seizures, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1161205-27-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
pH/Conductivity - Clay Soil
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
PHCz2BP
PHCz2BP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(4-(3,6-diphenyl-9H-carbazol-9-yl)phenyl)methanone. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1360642-12-1. Molecular formula: C61H40N2O. Mole weight: 816.98 g/mol. Product ID: ACM1360642121. Alfa Chemistry ISO 9001:2015 Certified.
PhD1
PhD1 is an antimicrobial peptide found in Papio hamadryas (Hamadryas baboon), and has antibacterial and antifungal activity. Synonyms: PhD-1; Defensin-1; Recombinant Papio hamadryas Defensin-1. Grade: >85%. Molecular formula: C167H276N62O37S6. Mole weight: 3936.75.
PhD2
PhD2 is an antimicrobial peptide found in petals, Petunia hybrida, and has antifungal activity. Synonyms: Floral defensin-like protein 2. Grade: >98%. Molecular formula: C227H375N67O65S10. Mole weight: 5403.48.
PhDave-Phos
PhDave-Phos. Uses: Useful ligand for sterically hindered substrates in the pd-catalyzed amination reactions of aryl bromides. ligand used for the cu-catalyzed phosphorylation of alcohols. ligand for pd-catalyzed c-h benzylation. ligand for palladium-catalyzed [4 + 2] benzannulation reaction. Additional or Alternative Names: SY030636; 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE; 2-Dimethylamino-2'-(diphenylphosphino)biphenyl; RL02764; AKOS015840665; 2-(Diphenylphosphino)-2 inverted exclamation mark -(N,N-dimethylamino)biphenyl; 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE; 2'-(diphenylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine; 2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL; AN-11455. Product Category: Organic Phosphine Compounds. CAS No. 240417-00-9. Molecular formula: C26H24NP. Mole weight: 381.459g/mol. IUPACName: 2-(2-diphenylphosphanylphenyl)-N,N-dimethylaniline. Canonical SMILES: CN(C)C1=CC=CC=C1C2=CC=CC=C2P(C3=CC=CC=C3)C4=CC=CC=C4. Product ID: ACM240417009. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-(DIPHENYLPHOSPHINO)-2'-(N,N-DIMETHYLAMINO)BIPHENYL.
PhDave-Phos
PhDave-Phos. Group: Biochemicals. Alternative Names: 2-Diphenylphosphino-2'- (N, N-dimethylamino) biphenyl. Grades: Highly Purified. CAS No. 240417-00-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H24N1P. US Biological Life Sciences.
ACTH (1-24) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Synonyms: 2-Phenylalanyl-4-norleucine-acth(1-24); ACTH (1-24), phe(2)-nle(4)-; alpha1-24-Corticotropin, 2-L-phenylalanine-4-L-norleucine-; (Phe2,Nle4)-ACTH (1-24) (human, bovine, rat). CAS No. 97773-00-7. Molecular formula: C137H212N40O30. Mole weight: 2899.40.
Phe(5-Br-2-CF2H)
Phe(5-Br-2-CF2H) is a modified phenylalanine derivative where the phenyl ring is substituted with a bromine (Br) atom at the 5-position and a difluoromethyl group (CF2H) at the 2-position. This combination of halogenation and the trifluoromethyl group introduces strong electron-withdrawing effects and enhances the hydrophobicity of the phenylalanine residue. Such modifications are used in peptide synthesis to influence the structure, stability, and biological interactions of peptides, potentially improving their performance in therapeutic or research settings. The specific substitution pattern is particularly useful for altering binding affinity, resistance to degradation, or other key properties in peptide-based compounds. Synonyms: 5-Bromo-2-difluoromethyl-L-phenylalanine; 5-Bromo-2-(difluoromethyl)-L-phenylalanine. Grade: ≥95%. Molecular formula: C10H10BrF2NO2. Mole weight: 294.10.
Phe(5-Cl-2-CF2H)
Phe(5-Cl-2-CF2H) is a modified phenylalanine derivative where the phenyl ring is substituted with a chlorine (Cl) atom at the 5-position and a difluoromethyl group (CF2H) at the 2-position. This modification introduces both electron-withdrawing effects and increased hydrophobicity to the phenylalanine residue. Such derivatives are used in peptide synthesis to alter the chemical and physical properties of peptides, potentially enhancing their stability, bioavailability, or binding affinity in biological applications. This specific substitution pattern can be useful in fine-tuning the activity and selectivity of peptide-based drugs or research compounds. Synonyms: 5-Chloro-2-difluoromethyl-L-phenylalanine; 5-Chloro-2-(difluoromethyl)-L-phenylalanine. Grade: ≥95%. Molecular formula: C10H10ClF2NO2. Mole weight: 249.64.
It is produced by the strain of Str. sp. MJ 716-m3. It has inhibitory effect on aminopeptidase N (AP-N), AP-A, AP-B with IC50 (μg/mL) of 0.18, 9.0 and 9.1, respectively, but it has no antimicrobial activity (100 μg/mL). Synonyms: N-((2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbuty)-L-valyl-L-phenylalanine; ((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-valyl-L-phenylalanine; L-Phenylalanine, N-((2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbuty)-L-valyl-. Grade: ≥99%. CAS No. 187402-73-9. Molecular formula: C24H31N3O5. Mole weight: 441.52.
Phe-Glu-Cys-Gly is a tetrapeptide comprising L-phenylalanine, L-α-glutamic acid, L-cysteine, and glycine. L-phenylalanine is an essential amino acid important for protein synthesis and the production of neurotransmitters. L-α-glutamic acid plays a role in cellular metabolism and neurotransmission. L-cysteine is a sulfur-containing amino acid involved in antioxidant defense and protein structure. Glycine contributes to collagen formation and various metabolic processes. This peptide combines these amino acids to potentially support metabolic processes, antioxidant defenses, and overall health. Synonyms: FECG; (S)-4-((S)-2-Amino-3-phenylpropanamido)-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid; L-Phenyl-L-α-glutamyl-L-cysteinylglycine; H-Phe-Glu-Cys-Gly-OH; H-FECG-OH. Grade: ≥90%. Molecular formula: C19H26N4O7S. Mole weight: 454.50.