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| Product | Description | |
|---|---|---|
| Petroleum Ether, Laboratory Grade, 3.8 L | Characteristic: Clear, colorless liquid. Notes: Consider hexanes as a less flammable alternative and a green chemistry substitute. Storage Code: Red; flammable. DOT Class: Flammable. Alternative Names: Ligroine, naphtha. Grades: chem-grade laboratory. CAS No. 8032-32-4. Product ID: 879542. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Petroleum Ether, Laboratory Grade, 500 mL | Characteristic: Clear, colorless liquid. Notes: Consider hexanes as a less flammable alternative and a green chemistry substitute. Storage Code: Red; flammable. DOT Class: Flammable. Alternative Names: Ligroine, naphtha. Grades: chem-grade laboratory. CAS No. 8032-32-4. Product ID: 879540. -- SOLD FOR EDUCATIONAL USE ONLY -- | |
| Petroleum Hydrocarbon Resin C9 | Petroleum Hydrocarbon Resin C9. Group: Polymers. CAS No. 64742-16-1. |  |
| Petroleum Hydrocarbon Surrogate Solution | ?g/mL in methylene chloride (varied conc.), ampule of 5 mL, certified reference material. Group: Certified reference materials (crms). |  |
| Petroleum jelly | Petroleum jelly is a semi-solid mixture of hydrocarbons. CAS No. 8009-3-8. Product ID: CDC10-0488. Category: Moisturizers. Product Keywords: Cosmetic Ingredients; Moisturizers; Petroleum jelly; CDC10-0488; 8009-03-8; 232-373-2; MFCD00147839; 8009-03-8. EC Number: 232-373-2. Solubility: water: insoluble. Quality Level: 200. |  |
| Petroleum Jelly | Petroleum Jelly. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. |  California |
| Petroleum Jelly | Petroleum Jelly. Market: Food Additives / Preservatives, Cosmetics & Personal Care. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries. |  |
| Petroleum Jelly 3/8/09 | Petroleum Jelly 3/8/09. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Petroleum Jelly 8003-03-8 | Petroleum Jelly - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Petroleum resin C9 64742-16-1 | Petroleum resin C9 - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Petroleum resins | Petroleum resins. Group: Polymers. Alternative Names: Petrolium Resin; Resins, petroleum; Petroleum resins; hydrocarbon resin, postpolymerised with maleic anhydride. CAS No. 64742-16-1. | |
| Petromurin C | Petromurin C is a metabolite isolated as a component of bis-indolyl benzenoid complex from Aspergillus muricatus. It exhibits antitumor activity. Synonyms: 1H-Indol-5-ol, 3-[4-(1H-indol-3-yl)-2,3,5,6-tetramethoxyphenyl]-. Grades: ≥95%. CAS No. 194608-29-2. Molecular formula: C26H24N2O5. Mole weight: 444.48. |  |
| Petromyzonol | Petromyzonol. Group: Biochemicals. Alternative Names: 5-a-Cholane-3-a,7-a,12-a,24-tetrol; (3a,5a,7a,12a)Cholane-3,7,12,24-tetrol. Grades: Highly Purified. CAS No. 28979-29-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H42O4. US Biological Life Sciences. |  Worldwide |
| Petromyzonol 24 Hemisuccinate | Petromyzonol 24 Hemisuccinate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Petromyzonol-24-Sulfate, Sodium Salt (PZS) | Petromyzonol sulfate (PZS) is a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). PZS appears to be a spawning chemoattractant for the sea lamprey. Group: Biochemicals. Alternative Names: PZS. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Petromyzonol-3,7,12,21-tetrasulfate | A bile salt derivative isolated from the sea la. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Petromyzonol (5-a-Cholane-3-a,7-a,12-a,24-tetrol) | Petromyzonol sulfate (PZS) is a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). PZS appears to be a spawning chemoattractant for the sea lamprey. Group: Biochemicals. Alternative Names: 5-a-Cholane-3-a,7-a,12-a,24-tetrol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| petromyzonol sulfotransferase | The enzyme from the lamprey Petromyzon marinus can also use the corresponding 3-ketone as a substrate. It is stereoselective (5α-cholane) and regioselective, exhibiting a preference for an hydroxy group at C-24. The enzyme is inactive when allocholic acid, which has a carboxy group at C-24, is used as a substrate. Group: Enzymes. Synonyms: PZ-SULT. Enzyme Commission Number: EC 2.8.2.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3391; petromyzonol sulfotransferase; EC 2.8.2.31; PZ-SULT. Cat No: EXWM-3391. |  |
| Petro Resin | Petro Resin. Group: Polymers. | |
| Petroselinic acid | Petroselinic acid, a positional isomer of oleic acid, is isolated from the vegetable oil of Coriandrum sativum fruits. Petroselinic acid is used as substrate for sophorolipid fermentation [1]. Uses: Scientific research. Group: Natural products. CAS No. 593-39-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113362. |  |
| Petroselinic acid | ?99%, powder. Group: Fluorescence/luminescence spectroscopy. | |
| Petroselinic acid sodium salt | ~98%. Group: Fluorescence/luminescence spectroscopy. | |
| Petroselinyl alcohol | liquid. Group: Fluorescence/luminescence spectroscopy. | |
| PET Sirop Bottles | PET Sirop Bottles. Product ID: PM-043. Product Keywords: Packaging Materials; Plastic Packaging; PM-043; PET Sirop Bottles. | |
| PET Tablet Bottles | PET Tablet Bottles. Product ID: PM-042. Product Keywords: Packaging Materials; Plastic Packaging; PM-042; PET Tablet Bottles. | |
| PET Therapy Bottles-Clear, Amber White or Black | PET Therapy Bottles-Clear, Amber White or Black. Product ID: PM-049. Product Keywords: Packaging Materials; Plastic Packaging; PM-049; PET Therapy Bottles-Clear, Amber White or Black. | |
| Petunidin 3-D-Glucoside | Petunidin 3-D-Glucoside, a glycoside form of the O-methylated anthocyanidin, Petundin, shows anti-oxidant activities as well as having potential cytoprotective effects. Synonyms: Petunidin 3-O-β-D-Glucoside; 2-(3,4-dihydroxy-5-methoxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-1-benzopyrylium Chloride; 3-(Glucosyloxy)-3',4',5,7-tetrahydroxy-5'-methoxyflavylium Chloride; 3-(β-D-Glucopyranosyloxy)-3',4',5,7-tetrahydroxy-5'-methoxyflavylium Chloride; Petunidin 3-O-β-D-Glucopyranoside; Petunidin 3-Monoglucoside; Petunidin 3-β-D-Monoglucoside. Grades: > 95%. CAS No. 6988-81-4. Molecular formula: C22H23O12Cl. Mole weight: 514.86. | |
| Petunidin 3-glucoside | Petunidin 3-glucoside. CAS No. 26984-08-7. Product ID: 3-02775. Molecular formula: C22H23ClO12. Mole weight: 514.9. |  |
| Petunidin-3-O-glucoside chloride | Petunidin-3-O-glucoside chloride is a flavonoid isolated from Phaseolus vulgaris L. seed, has antioxidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 6988-81-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7832. | |
| Petunidin chloride | Petunidin chloride is an O-methylated anthocyanidin derived from delphinidin. Petunidin chloride binds with and suppresses the activity of focal adhesion kinase and to inhibit platelet-derived growth factor-induced aortic smooth muscle cell migration, which may confer a protective effect against atherosclerosis. Uses: Scientific research. Group: Natural products. CAS No. 1429-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126410. | |
| Peucedanol | Peucedanol. Group: Biochemicals. Alternative Names: Ohter Cas No, 20126-72-1. Grades: Plant Grade. CAS No. 20516-23-8. Pack Sizes: 10mg. Molecular Formula: C14H16O5, Molecular Weight: 264.274. US Biological Life Sciences. | Worldwide |
| Pevonedistat | Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. Uses: Enzyme inhibitors. Synonyms: TAK-924; TAK 924; TAK924; MLN4924; MLN 4924; BAY-73-4506; BAY 73-4506; BAY73-4506. Grades: ≥98% (HPLC). CAS No. 905579-51-3. Molecular formula: C21H25N5O4S. Mole weight: 443.52. | |
| Pevonedistat | Pevonedistat Inhibitor. Uses: Scientific use. Product Category: T6332. CAS No. 905579-51-3. |  |
| Pevonedistat | Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme ( NAE ) inhibitor with an IC 50 of 4.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN4924. CAS No. 905579-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-70062. | |
| Pevonedistat hydrochloride | Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC 50 of 4.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN4924 hydrochloride. CAS No. 1160295-21-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10484. | |
| PE wax | PE wax. Group: Polymers. | |
| Pexacerfont | Corticotropin-releasing factor (CRF), also known as corticotropin-releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress. Pexacerfont is a potent and orally active CRF-1 antagonist trials for the treatment of anxiety disorders, and has also been proposed to be useful for the treatment of depression and irritable bowel syndrome. Uses: Crf-1 antagonist. Synonyms: BMS-562086; BMS 562086; BMS562086; BMS-562,086; BMS562,086; BMS 562,086; Pexacerfont.8-(6-Methoxy-2-methylpyridin-3-yl)-2,7-dimethyl-N-((1R)-1-methylpropyl)pyrazolo(1,5-a)-1,3,5-triazin-4-amine. Grades: ≥98%. CAS No. 459856-18-9. Molecular formula: C18H24N6O. Mole weight: 340.43. | |
| Pexacerfont | Pexacerfont is a selective corticotropin-releasing factor ( CRF 1 ) receptor antagonist with IC 50 of 6.1±0.6 nM for human CRF 1 receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-562086. CAS No. 459856-18-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12127. | |
| Pexidartinib | Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC 50 s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX-3397. CAS No. 1029044-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749. | |
| Pexidartinib | Pexidartinib Inhibitor. Uses: Scientific use. Product Category: T2115. CAS No. 1029044-16-3. | |
| Pexidartinib hydrochloride | Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC 50 s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX-3397 hydrochloride. CAS No. 2040295-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749A. | |
| Pexidartinib (PLX3397) | Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R with IC50 of 20 nM, Kit with IC50 of 10 nM, and Flt3 with IC50 160 nM. Phase 3, respectively. Synonyms: PLX3397; PLX-3397; PLX 3397; Pexidartinib. Grades: 98%. CAS No. 1029044-16-3. Molecular formula: C20H15ClF3N5. Mole weight: 417.81. | |
| Pexiganan | Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections [1]. Uses: Scientific research. Group: Peptides. Alternative Names: MSI 78 free base. CAS No. 147664-63-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105088. | |
| Pexiganan | An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Grades: >95%. CAS No. 147664-63-9. Molecular formula: C122H209N31O23. Mole weight: 2478.19. | |
| Pexiganan acetate | An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Synonyms: MSI 78; Pexiganan. Grades: >98%. CAS No. 172820-23-4. Molecular formula: C122H210N32O22.C2H4O2. Mole weight: 2537.22. | |
| Pexmetinib | Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. It has potential antineoplastic, anti-inflammatory, and antiangiogenic activities. It inhibits other kinases including vascular endothelial growth factor receptor (VEGFR2) and Src tyrosine kinases. Synonyms: 1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)urea; Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]-; N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]urea; ARRY 614; ARRY-614; ARRY614; N-(3-tert-Butyl-1-p-tolyl-1H-pyrazol-5-yl)-N'-[5-fluoro-2-[1-(2-hydroxyethyl)-1H-indazol-5-yloxy]benzyl]urea. Grades: 98%. CAS No. 945614-12-0. Molecular formula: C31H33FN6O3. Mole weight: 556.63. | |
| PF-00337210 | PF-00337210 is an orally available ATP-competitive inhibitor of the vascular endothelial growth factor receptor type 2 (VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, the VEGFR2 tyrosine kinase inhibitor PF-00337210 selectively binds to VEGFR2 and prevents its phosphorylation which may result in an inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and may eventually cause tumor cell death. VEGFR2, a receptor tyrosine kinase, is frequently overexpressed by a variety of tumor types. Synonyms: PF00337210; PF 00337210; PF-00337210; P337210; PF-337210; PF337210. CAS No. 854514-88-8. Molecular formula: C26H27N3O5. Mole weight: 461.51. | |
| PF 00356231 | PF 00356231 is a MMP-12 inhibitor, and at high concentrations it also inhibits other MMPs. Synonyms: PF 00356231; PF00356231; PF-00356231; (3R)-3-phenyl-3-[[4-(4-pyridin-4-ylphenyl)thiophene-2-carbonyl]amino]propanoic acid. Grades: 98%. CAS No. 766536-21-4. Molecular formula: C25H20N2O3S. Mole weight: 428.5. | |
| PF-00356231 hydrochloride | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 ( IC 50 =1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC 50 s of 0.00065, 1.7, 0.98, 0.39 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 820223-77-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114091. | |
| Pf-01247324 | PF-01247324 is a subtype-selective Nav1.8 blocker, for study cerebellar dysfunction in MS and related disorders. Uses: Pf-01247324 is a selective nav 1.8 channel blocker. Synonyms: 6-amino-N-methyl-5-(2,3,5-trichlorophenyl)picolinamide; PF 01247324. Grades: 98%. CAS No. 875051-72-2. Molecular formula: C13H10Cl3N3O. Mole weight: 330.60. | |
| PF-01247324 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-02413873 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03049423 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03084014 | Cas No. 865773-15-5. | |
| PF-03084014 hydrobromide | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03246799 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03463275 | PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a K i of 11.6 nM. PF-03463275 has the potential for Schizophrenia research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173239-39-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10716A. | |
| PF-03549184 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03654746 Tosylate | PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms [1]. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1039399-17-1. Pack Sizes: 1 mg. Product ID: HY-11044. | |
| PF-03654746 Tosylate | PF-03654746 Tosylate is a histamine H3 receptor antagonist undergoing a clinical trial for attention-deficit hyperactivity disorder (ADHD) therapy. Uses: Potential treatment of adhd. Synonyms: Trans-N-Ethyl-3-fluoro-3-[3-fluoro-4-(1-pyrrolidinylmethyl)phenyl]-cyclobutanecarboxamide 4-methylbenzenesulfonate; PF-03654746, 4-Methylbenzenesulfonate. Grades: 99%. CAS No. 1039399-17-1. Molecular formula: C18H24F2N2O.C7H8O3S. Mole weight: 494.59. | |
| PF-03671148 | PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring. Synonyms: PF03671148; PF 03671148. CAS No. 1378524-25-4. Molecular formula: C18H15N5O. Mole weight: 317.35. | |
| PF 03716556 | PF 03716556 is a potent, selective, competitive and reversible acid pump (H + ,K + -ATPase) antagonist with pIC 50 s of 6.026, 6.038 and 6.009 for porcine , canine , and human recombinant gastric H + ,K + -ATPase , respectively. PF 03716556 is inactive against other receptors, ion channels, and enzymes. PF 03716556 has the potential for gastroesophageal reflux disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 928774-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13100. | |
| PF-03716556 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03732010 | PF-03732010 is a humanized antibody expressed in CHO, targeting CDH3/P-cadherin. PF-03732010 has a huIgG1 type heavy chain and a huλ type light chain, with a predicted molecular weight (MW) of 142.7 kDa. The isotype control for PF-03732010 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2070913-84-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990645. | |
| PF-03758309 | PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also an orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival. Synonyms: PF03758309; PF 03758309; PF-3758309; PF3758309; PF 3758309. Grades: >98%. CAS No. 898044-15-0. Molecular formula: C25H30N8OS. Mole weight: 490.63. | |
| PF 03814735 | PF 03814735 is an orally bioavailable small molecule aurora kinase inhibitor that plays a key role in the regulation of mitosis. PF 03814735 is a anticancer agent used for cancer therapy. Group: Biochemicals. Alternative Names: N-[2-[(1S,4R)-6-[[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]-acetamide. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PF-03814735 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PF-03814735 | PF-03814735 is an orally bioavailable, ATP-competitive, reversible small-molecule Aurora kinase inhibitor with potential antineoplastic activity. Aurora kinase inhibitor PF-03814735 binds to and inhibits Aurora kinases A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Aurora kinases are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Synonyms: PF03814735; PF-03814735; PF 03814735. Grades: >98%. CAS No. 942487-16-3. Molecular formula: C23H25F3N6O2. Mole weight: 474.48. | |
| PF 03814735 (Aurora Kinases A and B, N-[2-[(1S,4R)-6-[[4-(Cyclobutylamin o)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3, 4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]- acetamide) | ATP-competitive inhibitor of Aurora kinases A and B (IC50 values are 0.8 and 5nm for recombinant Aurora B and Aurora A, respectively). Inhibits phosphorylation of Aurora B, histone H3 and Aurora A in cultured MDA-MB-231 cells (IC50 values are ~20, 50 and 150nm respectively). Shown to block cytokinesis; inhibits cellular proliferation in several human tumor cell lines, including HCT-116, HL-60, A549 and H125, and in human xenograft mouse models. Orally available. Group: Biochemicals. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-04171327 | PF-04171327 is a dissociated agonist of the glucocorticoid receptor (DAGR), which is a selective high-affinity partial agonist of the GR. It has potent anti-inflammatory activity at exposures which provide less undesirable effects on bone and glucose metabolism. It is used to the treatment of rheumatoid arthritis. It was developed by Pfizer and was terminated in clinic phase 2. Uses: Pf-04171327 has potent anti-inflammatory activity. it is used to the treatment of rheumatoid arthritis. Synonyms: PF-04171327; PF04171327; PF 04171327; PF-4171327; PF4171327; PF 4171327; Fosdagrocorat;(2R,4aS,10aR)-4a-benzyl-7-((2-methylpyridin-3-yl)carbamoyl)-2-(trifluoromethyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthren-2-yl dihydrogen phosphate. Grades: >98 %. CAS No. 1044535-58-1. Molecular formula: C29H30F3N2O5P. Mole weight: 574.53. | |
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