A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PFI-2 hydrochloride is a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM) and is approximately 1,000-fold selective over a panel of 18 other methyltransferases. Besides, following activation of the Hippo signaling pathway in MCF7 cells it inhibits. Synonyms: PFI-2 hydrochloride; PFI 2 hydrochloride; PFI2 hydrochloride; 8-fluoro-N-[(2R)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.98.
PFI-2 hydrochloride
PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC 50 value of 2.0??nM and (S)-PFI-2 shows inhibiting activity with IC 50 ?value of?1.0??μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-PFI-2 hydrochloride. CAS No. 1627607-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18627A.
PFI-2 Hydrochloride
PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0??nM and (S)-PFI-2 shows inhibiting activity with IC50 ?value of?1.0??μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis. Group: Inhibitors. Alternative Names: PFI-2; PFI2; PFI 2; (R)-PFI-2; (R)-PFI-2 hydrochloride. PFI-2 hydrochloride. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.9826 g/mol. Appearance: Solid powder. Purity: ≥98%. IUPACName: (R)-8-fluoro-N- (1-oxo-1- (pyrrolidin-1-yl)-3- (3- (trifluoromethyl)phenyl)propan-2-yl)-1, 2, 3, 4-tetrahydroisoquinoline-6-sulfonamide hydrochloride. Canonical SMILES: O=S (C1=CC2=C (CNCC2)C (F)=C1) (N[C@H] (CC3=CC=CC (C (F) (F)F)=C3)C (N4CCCC4)=O)=O. [H]Cl. Catalog: ACM1627607877.
PFI-3
PFI-3, a potent and selective SMARCA2/4 bromodomain inhibitor, is a cell-permeable probe that binds avidly to the structurally-similar SMARCA4 bromodomain (Kd= 89 nM) and PB1(bromodomain 5) (Kd= 48 nM). Synonyms: PFI-3; PFI 3; PFI3. (E)-1-(2-hyd roxyphenyl)-3-[(1R,4R)-2-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-5-yl]prop-2-en-1-one; PF-06687252; PFI-3 compound; PF 06687252; PF06687252. Grades: >98%. CAS No. 1819363-80-8. Molecular formula: C19H19N3O2. Mole weight: 321.38.
PFI-4
PFI-4 is a potent and selective BRPF1 bromodomain inhibitor with IC50 of 80 nM. Synonyms: PFI-4; PFI 4; PFI4. Grades: 98%. CAS No. 900305-37-5. Molecular formula: C21H24N4O3. Mole weight: 380.44.
PFI-653
PFI-653, also known as Vanin-1-IN-1, is an inhibitor of vanin-1 (VNN1) enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation. Group: Inhibitors. Alternative Names: PFI-653; PFI 653; PFI653; Vanin-1-IN-1; Vanin-1IN-1; Vanin-1 IN-1. CAS No. 2173134-00-2. Molecular formula: C18H22N6O2. Mole weight: 354.41. Appearance: Solid powder. Purity: >98%. IUPACName: (2-((pyrazin-2-ylmethyl)amino)pyrimidin-5-yl)(8-oxa-2-azaspiro[4.5]decan-2-yl)methanone. Canonical SMILES: O=C (N1CC2 (CCOCC2)CC1)C3=CN=C (NCC4=NC=CN=C4)N=C3. Catalog: ACM2173134002.
PFK15
PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment. Synonyms: PFK 015; PFK015; 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one. Grades: >98%. CAS No. 4382-63-2. Molecular formula: C17H12N2O. Mole weight: 260.29.
PFK-158
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. PFKFB3, an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-2,6-bisphosphate, is highly expressed and active in human cancer cells; it plays a key role in increasing both glycolytic flux in and proliferation of cancer cells. Synonyms: PFK158; PFK 158; PFK158; ACTPFK158. Grades: >98%. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29.
PFK-158
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. Group: Inhibitors. Alternative Names: PFK158; PFK 158; PFK158; ACTPFK158. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. Appearance: Solid powder. Purity: >98%. IUPACName: (E)-1-(pyridin-4-yl)-3-(7-(trifluoromethyl)quinolin-2-yl)prop-2-en-1-one. Canonical SMILES: O=C (C1=CC=NC=C1)/C=C/C2=NC3=CC (C (F) (F)F)=CC=C3C=C2. Catalog: ACM1462249757.
A cell-permeable dipyridinyl-propenone compound that selectively blocks PFK-2 (6-phosphofructo-2-kinase) activity of PFKFB3 isozyme over PFK-1 (6-phosphofructo-1-kinase) in a mixed-mode manner. Rapidly decreases fructose-2,6-bisphosphate (F-2,6-P2) and 2-deoxyglucose uptake, and lactate secretion; efficiently arrests proliferation of transformed cells (IC50 ~1.4uM in NHBE-ht/LT/ras) and suppresses tumor growth in several xenograft mouse models (70mg/kg, i.p.). The cytostatic and cytotoxic effects of 3PO is shown to be highly sensitive to the intracellular levels of F-6-P (fructose-6-phosphate) and F-2,6-P2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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p-Fluoro-a-acetamidocinnamic acid
Heterocyclic Organic Compound. Alternative Names: p-Fluoro-α-acetamidocinnamic Acid. CAS No. 111649-72-0. Molecular formula: C11H10FNO3. Appearance: White Crystalline Solid. Catalog: ACM111649720.
p-Fluoro-a-acetamidocinnamic Acid
p-Fluoro-a-acetamidocinnamic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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p-Fluorobenzyl Chloride
p-Fluorobenzyl Chloride. Group: Biochemicals. Alternative Names: α-Chloro-4-fluorotoluene; α-Chloro-p-fluorotoluene; 1-(Chloromethyl)-4-fluorobenzene; 4-Fluorobenzyl Chloride; 4-Fluorophenylmethyl Chloride; NSC 25084; 1-(Chloromethyl)-4-fluorobenzene. Grades: Highly Purified. CAS No. 352-11-4. Pack Sizes: 10g. Molecular Formula: C7H6ClF, Molecular Weight: 144.57. US Biological Life Sciences.
p-Fluorophenyl-2-thienylketone. Group: Biochemicals. Alternative Names: (4-Fluorophenyl)-2-thienylmethanone. Grades: Highly Purified. CAS No. 579-49-7. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
p-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers)
Intermediate in the synthesis of p-Fluoro Prasugrel (F595875). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(4-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
p-Fluoropropiophenone
p-Fluoropropiophenone. Group: Biochemicals. Grades: Highly Purified. CAS No. 456-03-1. Pack Sizes: 50g, 100g. US Biological Life Sciences.
PFM 01, a cell-permeable N-alkylated Mirin derivative, is a nuclease-specific MRE11 inhibitor, which enhances non-homologous end-joining (NHEJ) and reduces homologous recombination. Synonyms: (5Z)-5-[(4-Hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone; PFM01; PFM-01; PFM 01. Grades: ≥98% by HPLC. CAS No. 1558598-41-6. Molecular formula: C14H15NO2S2. Mole weight: 293.4.
PFN-DOF
Phosphorescent host material. Polymer for use in electron transport layer in OPV and OLED applications. Uses: Phosphorescent host material. polymer for use in electron transport layer in opv and oled applications. Group: Organic light emitting diode (oled). Alternative Names: Poly[(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)]. CAS No. 673474-75-4. Molecular formula: (C52H70N2)n. Appearance: solid. Catalog: ACM673474754-1.
PFN-DOF
Phosphorescent host material. Polymer for use in electron transport layer in OPV and OLED applications. Uses: Phosphorescent host material. polymer for use in electron transport layer in opv and oled applications. Group: Organic light-emitting diode (oled) materials. Alternative Names: Poly[(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)]. CAS No. 673474-75-4. Mole weight: (C52H70N2)n.
PFN-FP-I
Organic Light Emitting Diode (OLED). Alternative Names: Poly[(9,9-bis(3'-(N,N-trimethylamino)propyl)-2,7-fluorene)-alt-1,4-phenylene]diiodide. CAS No. 1026670-72-3. Molecular formula: (C31H40I2N2)n. Catalog: ACM1026670723-1.
PFO
Organic Light Emitting Diode (OLED). Alternative Names: Poly(9,9-dioctylfluorenyl-2,7-diyl). CAS No. 123864-00-6. Molecular formula: (C29H40)n. Catalog: ACM123864006.
PFO-DBT
PFO-DBT. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials.
PFQa-St2
PFQa-St2 is an antimicrobial peptide found in the African clawed frog Silurana tropicalis, and has anti-gram-positive bacteria, gram-negative bacteria and Mammalian cells activity. Synonyms: Phe-Ile-Gly-Ala-Leu-Leu-Arg-Pro-Ala-Leu-Lys-Leu-Leu-Ala-Gly-Lys. Grades: ≥97%. Molecular formula: C81H141N21O17. Mole weight: 1681.15.
Pfu DNA Polymerase
Pfu DNA Polymerase. Pfu dna polymerase is a fast, high fidelity and high processivity hot start dna polymerase. extension rate is about 2-4 kb/min. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3015.
PG 01
PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. PG 01 is effective on G970R although with a significant decrease in potency relative to E193K and ΔF508. Synonyms: PG 01; PG-01; PG01; N-Methyl-N-[2-[[4-(1-Methylethyl)phenyl]amino]-2-1H-indole-3-acetamide. Grades: ≥98% by HPLC. CAS No. 853138-65-5. Molecular formula: C28H29N3O2. Mole weight: 439.55.
PG 01
PG 01. Group: Biochemicals. Grades: Purified. CAS No. 853138-65-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PG 01037 dihydrochloride
PG 01037 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 675599-62-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PG 01037 dihydrochloride
PG 01037 dihydrochloride is a dopamine D3 receptor antagonist, which is more selective for D3 receptors than other D3 antagonists that are currently available with a D2/D3 selectivity ratio of 867 and a D4/D3 selectivity ratio of 13,000 (Ki values are 0.70, 93.3 and 375 nM for D3, D2 and D4 receptors respectively). Synonyms: N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamide dihydrochloride; PG 01037 dihydrochloride; PG 01037 diHCl; PG 01037; PG01037; PG-01037. Grades: ≥98%. CAS No. 675599-62-9. Molecular formula: C26H26Cl2N4O.2HCl. Mole weight: 554.34.
PG 106
PG 106. Group: Biochemicals. Grades: Purified. CAS No. 944111-22-2. Pack Sizes: 1mg. US Biological Life Sciences.
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PG 106
PG 106 is a selective human melanocortin receptor 3 (hMC3R) antagonist (IC50 = 210 nM), with no activity at hMC4 receptors and hMC5 receptors. PG 106 may be used to differentiate the substructural features responsible for selectivity at the hMC3R, hMC4R, and hMC5R. Synonyms: PG106; PG-106; Ac-DL-Nle-Asp(1)-bAla-D-2Nal-Arg-Trp-Lys(1)-NH2; N-Acetyl-L-norleucyl-L-α-aspartyl-β-alanyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-Lysinamide(2?7)-lactam; Ac-Nle-cyclo(-Asp-β-Ala-D-2-Nal-Arg-Trp-Lys)-NH2. Grades: >98%. CAS No. 944111-22-2. Molecular formula: C51H69N13O9. Mole weight: 1008.19.
pG(2',5')pA
pG(2',5')pA is a potential metabolite of 2'3'-cGAMP, the metazoan cyclic dinucleotide second messenger. Synonyms: 5'- Phosphoguanylyl- (2' -≥ 5')- adenosine, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 55779-55-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4.
PG 34
PG 34 is a weak O-GlcNAc transferase ( OGT ) inhibitor ( IC 50 =68 μM), and a close structural analog of OSMI-1 (HY-119738) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1681056-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148113.
PG490-88
PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47.
PG545
PG545 is an angiogenesis and heparanase inhibitor, which inhibited the proliferation, migration, and colony formation of pancreatic cancer cells in vitro at pharmacologically relevant concentrations. PG545 significantly prolonged animal survival in intraperitoneal and genetic models (mPDAC: LSL-Kras(G12D); Cdkn2a(lox/lox); p48(Cre)) of PDAC. PG545 also inhibited primary tumor growth and metastasis in orthotopic and genetic endpoint studies. PG545 significantly decreased cell proliferation, increased apoptosis, reduced microvessel density, disrupted vascular function, and elevated intratumoral hypoxia. Synonyms: PG 545; PG-545. CAS No. 1144492-69-2. Molecular formula: C51H75Na13O60S13. Mole weight: 2363.75.
PG 931. Group: Biochemicals. Grades: Purified. CAS No. 667430-81-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PG-931
PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor ( IC 50 =0.58 nM) agonist and is more selective than for the hMC3R ( IC 50 =55 nM) or the hMC5R ( IC 50 =2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo [2]. Uses: Scientific research. Group: Peptides. CAS No. 667430-81-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1208.
PG 97-269
PG 97-269, a selective high affinity VPAC1 receptor antagonist, has negligible affinity for PACAP type I receptors, with Kis of 15±5 and 2±1 nM for the rat and human VPAC1 receptors, respectively. It can be used to evaluate the physiological role of VIP in rats and human tissues. Synonyms: Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27); Ac-His-D-Phe-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2; L-Leucinamide, N-acetyl-L-histidyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-lysyl-L-arginyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-. Grades: ≥95%. CAS No. 202463-00-1. Molecular formula: C150H246N44O38. Mole weight: 3273.83.
PG-9 maleate
PG-9 maleate. Group: Biochemicals. Grades: Purified. CAS No. 155649-00-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PG-9 maleate
PG-9 maleate, derived from (+)-R-hyoscyamine, is a potent analgesic and nootropic agent, which increases release of acetylcholine. Synonyms: PG-9 maleate; PG 9 maleate; PG9 maleate; Tropanyl 2-(4-bromophenyl)propionate maleate. CAS No. 155649-00-6. Molecular formula: C17H22BrNO2.C4H4O4. Mole weight: 468.34.
PgAFP
PgAFP is an antimicrobial peptide found in Penicillium chrysogenum RP42C (Penicillium notatum), and has antifungal activity. Synonyms: Antifungal protein; afp. Grades: >98%. Molecular formula: C272H431N89O85S6. Mole weight: 6500.32.
Pg-AMP1
Pg-AMP1 is an antimicrobial peptide found in Psidium guajava (Guava, Psidium pyriferum), and has anti-gram-positive bacteria and gram-negative bacteria activity. Synonyms: Glycine-rich antimicrobial peptide Pg-AMP. Grades: >98%. Mole weight: 6029.00.
PGD2-IN-1
PGD2-IN-1 is an antagonist of DP (IC50 = 0.3 nM). Synonyms: MDK66671; MDK-66671 MDK 66671; PGD2-IN-1; PGD2 IN 1; 2-[3-[6-[2-(2,4-dichlorophenyl)ethylamino]-2-methoxypyrimidin-4-yl]phenyl]-2-methylpropanoic acid. CAS No. 885066-67-1. Molecular formula: C23H23Cl2N3O3. Mole weight: 460.35.
PG-Hydroxyethylcellulose Cocodimonium Chloride
Antistatic. Group: Antistatic agents. Alternative Names: Propanaminium, N-coco-alkyl-N,N-dimethyl-2,3-dihydroxy-, 3-ethers with 2-hydroxyethylcellulose, chlorides. CAS No. 130353-64-9. Catalog: ACM130353649.
PG-KI
PG-KI is an antimicrobial peptide found in Pseudophryne guentheri (Australian myobatrachid frog, Guenther's toadlet), and has antimicrobial activity. Synonyms: pGlu-Pro-His-Pro-Asp-Glu-Phe-Val-Gly-Leu-Met-NH2; Kassinin-Like Peptide K-I; Recombinant Pseudophryne guentheri Kassinin-like peptide K-I. Grades: ≥97%. Molecular formula: C57H82N14O16S. Mole weight: 1251.43.
PG-KII
PG-KII is an antimicrobial peptide found in Pseudophryne guentheri (Australian myobatrachid frog, Guenther's toadlet), and has antimicrobial activity. Synonyms: pGlu-Pro-Asn-Pro-Asp-Glu-Phe-Val-Gly-Leu-Met-NH2; H-Pyr-Pro-Asn-Pro-Asp-Glu-Phe-Val-Gly-Leu-Met-NH2; L-pyroglutamyl-L-prolyl-L-asparagyl-L-prolyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; L-Methioninamide, 5-oxo-L-prolyl-L-prolyl-L-asparaginyl-L-prolyl-L-α-aspartyl-L-α-glutamyl-L-phenylalanyl-L-valylglycyl-L-leucyl-; Kassinin-Like Peptide K-II; Recombinant Pseudophryne guentheri Kassinin-like peptide K-II. Grades: ≥95%. CAS No. 127633-77-6. Molecular formula: C55H81N13O17S. Mole weight: 1228.37.
PG-KIII
PG-KIII is an antimicrobial peptide found in Pseudophryne guentheri (Australian myobatrachid frog, Guenther's toadlet), and has antimicrobial activity. Synonyms: pGlu-Pro-His-Pro-Asn-Glu-Phe-Val-Gly-Leu-Met-NH2; Kassinin-Like Peptide K-III; Recombinant Pseudophryne guentheri Kassinin-like peptide K-III. Grades: ≥97%. Molecular formula: C57H83N15O15S. Mole weight: 1250.44.
PG-L
PG-L is an antimicrobial peptide found in Pseudophryne guentheri (Australian myobatrachid frog, Guenther's toadlet), and has antimicrobial activity. Synonyms: H-Glu-Gly-Gly-Gly-Pro-Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2; pGlu-Gly-Gly-Gly-Pro-Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2; litorin-like peptide L (PG-L); Recombinant Pseudophryne guentheri Bombesin-like peptide L; L-alpha-glutamyl-glycyl-glycyl-glycyl-L-prolyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-phenylalanyl-L-methioninamide. Grades: ≥97%. Molecular formula: C62H86N18O16S. Mole weight: 1371.52.
PGLa
PGLa is an antimicrobial peptide (AMP) composed of 21 amino acids which form an alpha-helical secondary structure. It has a wide variety of antimicrobial activity including activity against fungi, viruses, gram-negative and gram-positive bacteria, and cancer cells. Synonyms: PYLa/PGLa precursor; Gla peptide. Grades: ≥97% by HPLC. CAS No. 102068-15-5. Molecular formula: C88H162N26O22S. Mole weight: 1968.48.
PGLa acetate
PGLa is an antimicrobial peptide (AMP) composed of 21 amino acids which form an alpha-helical secondary structure. It has a wide variety of antimicrobial activity including activity against fungi, viruses, gram-negative and gram-positive bacteria, and cancer cells. Synonyms: PYLa/PGLa precursor acetate; Gla peptide acetate. Molecular formula: C90H166N26O24S. Mole weight: 2028.51.
PGLa-AM1
PGLa-AM1 is an antimicrobial peptide found in Xenopus amieti (skin secretions of the African volcano frog, Pipidae), and has antibacterial activity. Synonyms: Gly-Met-Ala-Ser-Lys-Ala-Gly-Ser-Val-Leu-Gly-Lys-Val-Ala-Lys-Val-Ala-Leu-Lys-Ala-Ala-Leu-NH2. Grades: ≥95%. Molecular formula: C92H169N27O24S. Mole weight: 2069.59.
PGLa-H
PGLa-H is an antimicrobial peptide found in Xenopus laevis (African clawed frog), and has antibacterial activity. Synonyms: Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu. Grades: ≥97%. CAS No. 1350308-37-0. Molecular formula: C50H95N13O11. Mole weight: 1054.37.
PGLa-St2
PGLa-St2 is an antimicrobial peptide found in the African clawed frog Silurana tropicalis, and has anti-gram-positive bacteria, gram-negative bacteria, fungal and Mammalian cells activity. Synonyms: Gly-Met-Ala-Thr-Lys-Ala-Gly-Thr-Ala-Phe-Gly-Lys-Ala-Ala-Lys-Ala-Ile-Ile-Gly-Ala-Ala-Leu-NH2. Grades: ≥96%. Molecular formula: C90H156N26O24S. Mole weight: 2018.46.
PGLU-ALA-GLU
Heterocyclic Organic Compound. CAS No. 108347-82-6. Purity: 0.96. Catalog: ACM108347826.
pGlu-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-NH2 is a peptide hormone that stimulates the synthesis of 1,2-diacyl-sn-glycerols in the Manduca sexta fat body. Synonyms: AKH (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta); Pyr-Leu-Thr-Phe-Thr-Ser-Ser-Trp-Gly-NH2; Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta); L-pyroglutamyl-L-leucyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-seryl-L-tryptophyl-glycinamide; 5-Oxo-L-prolyl-L-leucyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-seryl-L-tryptophylglycinamide. Grades: ≥95%. CAS No. 99886-31-4. Molecular formula: C47H65N11O14. Mole weight: 1008.08.
pGlu-Pro-Arg-MNA
pGlu-Pro-Arg-MNA is a peptide compound that has potential biology activity in many areas. Uses: Pglu-pro-arg-mna is a peptide compound that has potential biology activity in many areas. Synonyms: pGlu-PR-MNA; L-Argininamide, 5-oxo-L-prolyl-L-prolyl-N-(2-methoxy-4-nitrophenyl)-. Grades: 98%. CAS No. 130835-45-9. Molecular formula: C23H32N8O7. Mole weight: 532.55.
PGMEA
PGMEA. Group: Solvents. Alternative Names: Propylene glycol monomethyl ether acetate. CAS No. 108-65-6.
pGp
pGp is a vital protein transporter found in many human tissues. It plays a crucial role in determining drug resistance in various cancers such as breast cancer and leukemia. Understanding the mechanisms of pGp in drug efflux can open up new avenues for drug development and personalized medicine. Synonyms: guanosine 3',5'-diphosphate; guanosine 3',5'-bis(dihydrogen phosphate). Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N5O11P2. Mole weight: 443.20.
PGP-4008
PGP-4008 is a specific P-glycoprotein ( Pgp ) inhibitor. PGP-4008 inhibits tumor growth in a murine syngeneic Pgp-mediated multiple agent resistance (MDR) solid tumor model when given in combination with Doxorubicin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 365565-02-2. Pack Sizes: 10 mM * 1 mL; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119823.
PGP-4008
PGP-4008 is a selective P-glycoprotein (P-gp) inhibitor without modulating multidrug resistance-related protein 1 (MRP1). In combination with doxorubicin, PGP-4008 inhibited tumor growth in a murine syngeneic Pgp-mediated MDR solid tumor model. Synonyms: N-(1-Benzyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide. Grades: ≥95%. CAS No. 365565-02-2. Molecular formula: C26H23N3O. Mole weight: 393.5.
pGpA
A STING agonist negative control (pGpA). Synonyms: 3'5'-pGpA sodium salt; 3'3'-cGAMP Control. CAS No. 20137-01-3. Molecular formula: C20H23N10O14P2.3Na. Mole weight: 758.38.
PGPC
PGPC is an oxidized phospholipid formed under conditions of oxidative stress. It is a potent PPARα agonist. Synonyms: 1-Hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine; 1-Palmitoyl-2-glutaryl phosphatidylcholine; 1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine; 2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine; PC(16:0/5:0(COOH)). Grades: ≥98%. CAS No. 89947-79-5. Molecular formula: C29H56NO10P. Mole weight: 609.73.
pGpG
pGpG is a STING agonist negative control and c-diGMP metabolite. Synonyms: P; -(5'-Guanosyl)-P; -(5'-guanosyl)-(3'?5')-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 33008-99-0. Molecular formula: C20H26N10O15P2(free acid). Mole weight: 708.43 (free acid).