A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Selective α7 nAChR agonist. Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3 β4 and α1 β1δγ respectively, and % inhibition is < 1 and 5% for α4 β2 and hERG respectively). Orally active and brain penetrant. Group: Biochemicals. Alternative Names: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide Fumarate. Grades: Highly Purified. CAS No. 527680-57-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?O?, Molecular Weight: 404.41. US Biological Life Sciences.
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PHA 568487
PHA 568487 is an orally active and brain penetrant agonist of the alpha 7 nicotinic acetylcholine receptor (Ki = 44 and 2800 for α7 and 5-HT3 respectively, IC50=> 100 μM for α3β4 and α1β1δγ respectively, and % inhibition is < 1 and 5% for α4β2 and hERG respectively), which was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability. Synonyms: PHA 568487; PHA568487; PHA-568487; N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate. Grades: ≥99% by HPLC. CAS No. 527680-57-5. Molecular formula: C16H20N2O3.C4H4O4. Mole weight: 404.41.
PHA 568487 free base
PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor ( α-7 nAchR ) agonist. PHA 568487 free base reduces neuroinflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 527680-56-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129674.
PHA665752
PHA665752 is a small-molecule inhibitor of c-Met/HGF/SF signaling c-Met is highly expressed in most tumors from patients with advanced-stage, metastatic NBL. Furthermore, using the NBL cell line SH-EP as a model, PHA665752 was shown to inhibit cMet/HGF/SF signaling in vitro, suggesting c-Met inhibitors may have efficacy for blocking local progression and/or metastatic spread of c-Met-positive NBL in vivo. These are novel findings for this disease and suggest that further studies of agents targeting the c-Met/HGF axis in NBL are warranted. Synonyms: PHA-665752; PHA 665752. Grades: >98%. CAS No. 477575-56-7. Molecular formula: C32H34Cl2N4O4S. Mole weight: 641.608.
PHA-665752
PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met kinase ( K i=4 nM; IC 50=9 nM). PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 477575-56-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11107.
PHA-665752 ia a c-Met kinase inhibitor. PHA-665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases. Group: Biochemicals. Alternative Names: (3Z) -5-[[ (2, 6-dichlorophenyl) methyl]sulfonyl]-3-[[3, 5-dimethyl-4-[[ (2R) -2- (1-pyrrolidinylmethyl) -1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1, 3-dihydro-2H-indol-2-one Hydrate; PHA 665752 Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PHA-680626
PHA-680626 is a potent and selective PLK inhibitor. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases. PHA-680626 inhibits Plk1 (IC50 = 0.53 μM), Plk2 (IC50 = 0.07 μM) and Plk3 (IC50 = 1.61 μM). Synonyms: PHA 680626; PHA680626; 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 15; 4-(4-Methyl-piperazin-1-yl)-N-[5-(2-thiophen-2-yl-acetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-benzamide. Grades: 98%. CAS No. 398493-74-8. Molecular formula: C23H26N6O2S. Mole weight: 450.56.
PHA-680632
PHA-680632 is a is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM. PHA-680632 is also the first representative of a new class of Aurora inhibitors with a high potential for further development as an anticancer therapeutic. Synonyms: PHA-680632; PHA 680632; PHA680632. CAS No. 398493-79-3. Molecular formula: C28H35N7O2. Mole weight: 501.62.
PHA-767491
PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. Synonyms: PHA-767491; PHA767491; PHA 767491. CAS No. 845714-00-3. Molecular formula: C12H11N3O. Mole weight: 213.24.
PHA 767491 Dihydrochloride Salt
A potent and selective ATP-competitive dual inhibitor cdc7/cdk9. It blocks DNA synthesis and affects the phosphorylation of the replicative DNA helicase at Cdc7-dependent phosphorylation sites. Inhibits cell proliferation in a variety of human cell lines and induces apoptosis in a p53-independent manner in vivo. Also inhibits mitogen-activated protein kinase-activated protein kinase-2 (MK-2). Group: Biochemicals. Alternative Names: 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one Dihydrochloride;PHA 767491 Dihydrochloride Salt; PF-02334471. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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PHA 767491 hydrochloride
PHA 767491 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 942425-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
PHA-767491 hydrochloride is a potent, ATP-competitive dual Cdc7/Cdk9 inhibitor, which prevents initiation of DNA replication. It inhibits cell proliferation in a variety of human cell lines and induces apoptosis in a p53-independent manner in vivo. It also inhibits mitogen-activated protein kinase-activated protein kinase-2 (MK2). Synonyms: CAY-10572 hydrochloride; PHA-767491 hydrochloride; CAY 10572 hydrochloride; PHA 767491 hydrochloride; CAY10572 hydrochloride; PHA767491 hydrochloride. Grades: >98%. CAS No. 942425-68-5. Molecular formula: C12H12ClN3O. Mole weight: 249.7.
PHA-793887
PHA-793887 is an inhibitor of multiple cyclin dependent kinases (CDK) with activity against CDK2, CDK1 and CDK4. Although toxicity was acceptable at initial dose levels, PHA-793887 was poorly tolerated at doses ≥44 mg/m2. The most frequent events across all dose levels were gastrointestinal or nervous system events. PHA-793887 induces severe, dose-related hepatic toxicity, which was not predicted by pre-clinical models and currently precludes its further clinical development. Synonyms: PHA 793887; PHA793887. Grades: >98%. CAS No. 718630-59-2. Molecular formula: C19H31N5O2. Mole weight: 361.48.
Phaclofen
Phaclofen is a selective GABA B receptor antagonist. Phaclofen is a peripheral and central baclofen antagonist. Phaclofen maybe a potential compound in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 114012-12-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100798.
Phaclofen
Phaclofen. Group: Biochemicals. Grades: Purified. CAS No. 114012-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Phaclofen
Phaclofen, a phosphonic acid derivative of Baclofen, is a selective GABAB antagonist. Uses: Gaba antagonists. Synonyms: (RS)-3-Amino-2-(4-chlorophenyl)propylphosphonic acid. Grades: ≥97% by HPLC. CAS No. 114012-12-3. Molecular formula: C9H13ClNO3P. Mole weight: 249.63.
Phacolysine sodium salt. Group: Biochemicals. Alternative Names: 5,12-Dihydroquinoxalino[2,3-b]phenazine-2,9-disulfonic acid sodium salt; Jing ming; Phacolin. Grades: Highly Purified. CAS No. 3863-80-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C18H10N4Na2O6S2. US Biological Life Sciences.
Worldwide
Phallacidin
Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin [1]. Uses: Scientific research. Group: Peptides. CAS No. 26645-35-2. Pack Sizes: 1 mg. Product ID: HY-P2031.
Phalloidin
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome [1]. Uses: Scientific research. Group: Peptides. CAS No. 17466-45-4. Pack Sizes: 1 mg. Product ID: HY-P0028.
Phalloidin
Phalloidin. Group: Biochemicals. Grades: Purified. CAS No. 17466-45-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Phalloidin
Phalloidin, a heptapeptide phallotoxin produced by Amanita phalloides, the death cap mushroom, is an F-actin stabilizing toxin and aids cytoskeletal deorganization in WPMY-1 cells. It decreases dissociation rate constant for actin subunits from filament ends and lowers critical concentration for polymerization. Synonyms: Cyclo[L-alanyl-D-threonyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-(4R)-4,5-dihydroxy-L-leucyl] Cyclic (3?6)-thioether; 18, 9-(Iminoethaniminoethaniminoethanimin omethano)-17H-pyrrolo [1', 2': 5, 6] [1, 5, 8, 11 ] thiatri azacyclopentadecino [15, 1 4-b] indole Cyclic Peptide Derivative; NSC 523214; NSC-523214; NSC523214. CAS No. 17466-45-4. Molecular formula: C35H48N8O11S. Mole weight: 788.87.
Phalloidin-Atto 425
suitable for fluorescence, ?95.0% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 430LS
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 488
BioReagent, suitable for fluorescence, ?90% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 490LS
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 514
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 520
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 565
suitable for fluorescence, ?80% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 594
suitable for fluorescence, ?90% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 655
suitable for fluorescence, ?95.0% (sum of isomers, HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 665
suitable for fluorescence, ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 700
suitable for fluorescence, ?80.0% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 725
suitable for fluorescence, ?80% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 740
suitable for fluorescence, BioReagent. Group: Fluorescence/luminescence spectroscopy.
Phalloidin, Fluorescein Isothiocyanate Labeled
peptide from Amanita phalloides. Group: Fluorescence/luminescence spectroscopy.
peptide from Amanita phalloides. Group: Fluorescence/luminescence spectroscopy.
Phanerosporic acid
Phanerosporic acid is a fungal secondary metabolite isolated from Phanerochaete chrysosporium. It has antibacterial and antifungal activities. Synonyms: (-)-Phanerosporic Acid; Benzoic acid, 2,4-dihydroxy-6-[(14R)-14-hydroxypentadecyl]-. Grades: ≥95%. CAS No. 124709-28-0. Molecular formula: C22H36O5. Mole weight: 380.52.
Phantolide
Phantolide. Group: Biochemicals. Alternative Names: 1-(2,3-Dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl)ethanone; 1,1,2,3,3,6-Hexamethyl-5-indanyl methyl ketone; 6-Acetyl-1,1,2,3,3,5-hexamethylindan. Grades: Highly Purified. CAS No. 15323-35-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C17H24O. US Biological Life Sciences.
The enzyme from Fusarium solani, which is distinct from kievitone hydratase (EC 4.2.1.95), hydrates the methylbutenyl side-chain of the isoflavonoid phytoalexin, phaseollidin. Group: Enzymes. Synonyms: phaseollidin-hydrate hydro-lyase. Enzyme Commission Number: EC 4.2.1.97. CAS No. 143597-34-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5081; phaseollidin hydratase; EC 4.2.1.97; 143597-34-6; phaseollidin-hydrate hydro-lyase. Cat No: EXWM-5081.
PHCCC, a chromene derivative, has been found to be a mGluR4 positive allosteric modulator as well as group I metabotropic glutamate receptor antagonist. It has been found to exhibit anti-Parkinsonian activies in rats. IC50: 3 μM (Glutamate Receptor). Synonyms: PHCCC; (1aS,7Z,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide. Grades: 98%. CAS No. 179068-02-1. Molecular formula: C17H14N2O3. Mole weight: 294.31.
PHCCC
PHCCC is a Group I mGluR antagonist with an IC 50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179068-02-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100409.
A potent positive allosteric modulator selective for mGlu4 receptors (EC50 = 3uM). Also, a less potent agonist of mGlu6 receptors (EC50 = 15uM). Biologically active admitted systematically. Often used in assessing the functional roles of mGlu4 receptors or group III mGlu receptors in a variety of research areas, such as epileptic seizures, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1161205-27-1. Pack Sizes: 10mg. US Biological Life Sciences.
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pH/Conductivity - Clay Soil
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
PHCz2BP
PHCz2BP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(4-(3,6-diphenyl-9H-carbazol-9-yl)phenyl)methanone. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1360642-12-1. Molecular formula: C61H40N2O. Mole weight: 816.98 g/mol. Product ID: ACM1360642121. Alfa Chemistry ISO 9001:2015 Certified.
PhD1
PhD1 is an antimicrobial peptide found in Papio hamadryas (Hamadryas baboon), and has antibacterial and antifungal activity. Synonyms: PhD-1; Defensin-1; Recombinant Papio hamadryas Defensin-1. Grades: >85%. Molecular formula: C167H276N62O37S6. Mole weight: 3936.75.
PhD2
PhD2 is an antimicrobial peptide found in petals, Petunia hybrida, and has antifungal activity. Synonyms: Floral defensin-like protein 2. Grades: >98%. Molecular formula: C227H375N67O65S10. Mole weight: 5403.48.
PhDave-Phos
PhDave-Phos. Uses: Useful ligand for sterically hindered substrates in the pd-catalyzed amination reactions of aryl bromides. ligand used for the cu-catalyzed phosphorylation of alcohols. ligand for pd-catalyzed c-h benzylation. ligand for palladium-catalyzed [4 + 2] benzannulation reaction. Additional or Alternative Names: SY030636; 2'-(DIPHENYLPHOSPHINO)-N,N-DIMETHYLBIPHENYL-2-AMINE; 2-Dimethylamino-2'-(diphenylphosphino)biphenyl; RL02764; AKOS015840665; 2-(Diphenylphosphino)-2 inverted exclamation mark -(N,N-dimethylamino)biphenyl; 2'-(DIPHENYLPHOSPHINO)-N,N'-DIMETHYL-(1,1'-BIPHENYL)-2-AMINE; 2'-(diphenylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine; 2-DIPHENYLPHOSPHINO-2'-DIMETHYLAMINOBIPHENYL; AN-11455. Product Category: Organic Phosphine Compounds. CAS No. 240417-00-9. Molecular formula: C26H24NP. Mole weight: 381.459g/mol. IUPACName: 2-(2-diphenylphosphanylphenyl)-N,N-dimethylaniline. Canonical SMILES: CN(C)C1=CC=CC=C1C2=CC=CC=C2P(C3=CC=CC=C3)C4=CC=CC=C4. Product ID: ACM240417009. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-(DIPHENYLPHOSPHINO)-2'-(N,N-DIMETHYLAMINO)BIPHENYL.
PhDave-Phos
PhDave-Phos. Group: Biochemicals. Alternative Names: 2-Diphenylphosphino-2'- (N, N-dimethylamino) biphenyl. Grades: Highly Purified. CAS No. 240417-00-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H24N1P. US Biological Life Sciences.
Worldwide
Phe(2)-nle(4)-acth(1-24)
ACTH (1-24) is a fragment of the ACTH hormone, which stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Synonyms: 2-Phenylalanyl-4-norleucine-acth(1-24); ACTH (1-24), phe(2)-nle(4)-; alpha1-24-Corticotropin, 2-L-phenylalanine-4-L-norleucine-; (Phe2,Nle4)-ACTH (1-24) (human, bovine, rat). CAS No. 97773-00-7. Molecular formula: C137H212N40O30. Mole weight: 2899.40.
Phe-Ala-OH
Synonyms: L-Phenylalanyl-L-alanine; (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid; Phe Ala OH. Grades: ≥ 95% (HPLC). CAS No. 3918-87-4. Molecular formula: C12H16N2O3. Mole weight: 236.27.
Phe-Ala-OH ≥95% (HPLC)
Phe-Ala-OH ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 3918-87-4. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Phe-Arg--beta-NA·2HCl
Phe-Arg--beta-NA·2HCl. Group: Biochemicals. Alternative Names: Phe-Arg b-naphthylamide dihydrochloride. Grades: Highly Purified. CAS No. 100929-99-5. Pack Sizes: 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
Phe-Arg-bNA·2HCl 99+% (TLC)
Phe-Arg-bNA·2HCl 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
It is produced by the strain of Str. sp. MJ 716-m3. It has inhibitory effect on aminopeptidase N (AP-N), AP-A, AP-B with IC50 (μg/mL) of 0.18, 9.0 and 9.1, respectively, but it has no antimicrobial activity (100 μg/mL). Synonyms: N-((2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbuty)-L-valyl-L-phenylalanine; ((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-valyl-L-phenylalanine; L-Phenylalanine, N-((2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbuty)-L-valyl-. Grades: ≥99%. CAS No. 187402-73-9. Molecular formula: C24H31N3O5. Mole weight: 441.52.
Phe-Gly-OH. Group: Biochemicals. Alternative Names: L-Phenylalanylglycine. Grades: Highly Purified. CAS No. 721-90-4. Pack Sizes: 1g, 2g. US Biological Life Sciences.
Worldwide
Phe-Gly-OH ≥95% (HPLC)
Phe-Gly-OH ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 721-90-4. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Phe-Leu-Arg-Phe amide
Phe-Leu-Arg-Phe amide. Group: Biochemicals. Grades: Highly Purified. CAS No. 104180-32-7. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C30H44N8O4. US Biological Life Sciences.