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| Product | Description | |
|---|---|---|
| PFI-1 | PFI-1. Group: Biochemicals. Alternative Names: 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide; 2-Methoxy-N- (1, 2, 3, 4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 1403764-72-6. Pack Sizes: 5mg. Molecular Formula: C16H17N3O4S, Molecular Weight: 347.39. US Biological Life Sciences. |  Worldwide |
| PFI-2 | PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. Synonyms: PFI-2; PFI 2; PFI2. Grades: >98%. CAS No. 1627676-59-8. Molecular formula: C23H25F4N3O3S. Mole weight: 499.52. |  |
| PFI-2 hydrochloride | PFI-2 hydrochloride is a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM) and is approximately 1,000-fold selective over a panel of 18 other methyltransferases. Besides, following activation of the Hippo signaling pathway in MCF7 cells it inhibits. Synonyms: PFI-2 hydrochloride; PFI 2 hydrochloride; PFI2 hydrochloride; 8-fluoro-N-[(2R)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.98. | |
| PFI-2 hydrochloride | PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC 50 value of 2.0??nM and (S)-PFI-2 shows inhibiting activity with IC 50 ?value of?1.0??μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-PFI-2 hydrochloride. CAS No. 1627607-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18627A. |  |
| PFI-2 Hydrochloride | PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0??nM and (S)-PFI-2 shows inhibiting activity with IC50 ?value of?1.0??μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PFI-2; PFI2; PFI 2; (R)-PFI-2; (R)-PFI-2 hydrochloride. PFI-2 hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.9826 g/mol. Purity: ≥98%. IUPACName: (R)-8-fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide hydrochloride. Canonical SMILES: O=S(C1=CC2=C(CNCC2)C(F)=C1)(N[C@H](CC3=CC=CC(C(F)(F)F)=C3)C(N4CCCC4)=O)=O.[H]Cl. Product ID: ACM1627607877. Alfa Chemistry ISO 9001:2015 Certified. |  |
| PFI-3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PFI-3 | PFI-3 is a selective, potent and cell-permeable SMARCA2/4 bromodomain inhibitor with a Kd of 89 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1819363-80-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12409. | |
| PFI-3 | PFI-3, a potent and selective SMARCA2/4 bromodomain inhibitor, is a cell-permeable probe that binds avidly to the structurally-similar SMARCA4 bromodomain (Kd= 89 nM) and PB1(bromodomain 5) (Kd= 48 nM). Synonyms: PFI-3; PFI 3; PFI3. (E)-1-(2-hyd roxyphenyl)-3-[(1R,4R)-2-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-5-yl]prop-2-en-1-one; PF-06687252; PFI-3 compound; PF 06687252; PF06687252. Grades: >98%. CAS No. 1819363-80-8. Molecular formula: C19H19N3O2. Mole weight: 321.38. | |
| PFI-4 | PFI-4 is a potent and selective BRPF1 bromodomain inhibitor with IC50 of 80 nM. Synonyms: PFI-4; PFI 4; PFI4. Grades: 98%. CAS No. 900305-37-5. Molecular formula: C21H24N4O3. Mole weight: 380.44. | |
| PFI-4 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PFI-653 | PFI-653, also known as Vanin-1-IN-1, is an inhibitor of vanin-1 (VNN1) enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PFI-653; PFI 653; PFI653; Vanin-1-IN-1; Vanin-1IN-1; Vanin-1 IN-1. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2173134-00-2. Molecular formula: C18H22N6O2. Mole weight: 354.41. Purity: >98%. IUPACName: (2-((pyrazin-2-ylmethyl)amino)pyrimidin-5-yl)(8-oxa-2-azaspiro[4.5]decan-2-yl)methanone. Canonical SMILES: O=C(N1CC2(CCOCC2)CC1)C3=CN=C(NCC4=NC=CN=C4)N=C3. Product ID: ACM2173134002. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFI-90 | PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1). Uses: Scientific research. Group: Signaling pathways. CAS No. 53995-62-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-139348. | |
| PFK-015 | PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4382-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12204. | |
| PFK15 | PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment. Synonyms: PFK 015; PFK015; 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one. Grades: >98%. CAS No. 4382-63-2. Molecular formula: C17H12N2O. Mole weight: 260.29. | |
| PFK15 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PFK-158 | PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. PFKFB3, an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-2,6-bisphosphate, is highly expressed and active in human cancer cells; it plays a key role in increasing both glycolytic flux in and proliferation of cancer cells. Synonyms: PFK158; PFK 158; PFK158; ACTPFK158. Grades: >98%. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. | |
| PFK-158 | PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PFK158; PFK 158; PFK158; ACTPFK158. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. Purity: >98%. IUPACName: (E)-1-(pyridin-4-yl)-3-(7-(trifluoromethyl)quinolin-2-yl)prop-2-en-1-one. Canonical SMILES: O=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2. Product ID: ACM1462249757. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFK-158 | PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1462249-75-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12203. | |
| PFKFB3 Inhibitor, 3PO (6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Inhibitor, 3PO, 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, (2E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one) | A cell-permeable dipyridinyl-propenone compound that selectively blocks PFK-2 (6-phosphofructo-2-kinase) activity of PFKFB3 isozyme over PFK-1 (6-phosphofructo-1-kinase) in a mixed-mode manner. Rapidly decreases fructose-2,6-bisphosphate (F-2,6-P2) and 2-deoxyglucose uptake, and lactate secretion; efficiently arrests proliferation of transformed cells (IC50 ~1.4uM in NHBE-ht/LT/ras) and suppresses tumor growth in several xenograft mouse models (70mg/kg, i.p.). The cytostatic and cytotoxic effects of 3PO is shown to be highly sensitive to the intracellular levels of F-6-P (fructose-6-phosphate) and F-2,6-P2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| p-Fluoro-a-acetamidocinnamic Acid | p-Fluoro-a-acetamidocinnamic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| p-Fluorobenzyl Chloride | p-Fluorobenzyl Chloride. Group: Biochemicals. Alternative Names: α-Chloro-4-fluorotoluene; α-Chloro-p-fluorotoluene; 1-(Chloromethyl)-4-fluorobenzene; 4-Fluorobenzyl Chloride; 4-Fluorophenylmethyl Chloride; NSC 25084; 1-(Chloromethyl)-4-fluorobenzene. Grades: Highly Purified. CAS No. 352-11-4. Pack Sizes: 10g. Molecular Formula: C7H6ClF, Molecular Weight: 144.57. US Biological Life Sciences. | Worldwide |
| p-Fluoro-DL-phenylalanine | p-Fluoro-DL-phenylalanine. Uses: Peptide synthesis. Additional or Alternative Names: 4-fluoro-phenylalanine. Product Category: Amino Acids. CAS No. 51-65-0. Molecular formula: FC6H4CH2CH(NH2)COOH. Mole weight: 183.18. Canonical SMILES: NC(Cc1ccc(F)cc1)C(O)=O. ECNumber: 200-113-7. Product ID: ACM51650. Alfa Chemistry ISO 9001:2015 Certified. | |
| p-Fluorohexahydro-sila-difenidol hydrochloride | powder, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| p-Fluorophenyl-2-thienylketone | p-Fluorophenyl-2-thienylketone. Group: Biochemicals. Alternative Names: (4-Fluorophenyl)-2-thienylmethanone. Grades: Highly Purified. CAS No. 579-49-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| p-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers) | Intermediate in the synthesis of p-Fluoro Prasugrel (F595875). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(4-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| p-Fluoropropiophenone | p-Fluoropropiophenone. Group: Biochemicals. Grades: Highly Purified. CAS No. 456-03-1. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| p-Fluorostyrene | p-Fluorostyrene. Group: Monomers. Alternative Names: 4-Fluorostyrene, 97%, stabilized; AS03795; ST2403438; RTR-033260; 4-Fluorostyrene, 99%; AN-44804; 405-99-2; ACN-S004611; CTK3J0456; I01-7785. CAS No. 405-99-2. Product ID: 1-ethenyl-4-fluorobenzene. Molecular formula: 122.142g/mol. Mole weight: C8H7F. C=CC1=CC=C(C=C1)F. InChI=1S/C8H7F/c1-2-7-3-5-8 (9)6-4-7/h2-6H, 1H2. JWVTWJNGILGLAT-UHFFFAOYSA-N. |  |
| PFM01 | PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1558598-41-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-116770. | |
| PFM01 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PFM 01 | PFM 01, a cell-permeable N-alkylated Mirin derivative, is a nuclease-specific MRE11 inhibitor, which enhances non-homologous end-joining (NHEJ) and reduces homologous recombination. Synonyms: (5Z)-5-[(4-Hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone; PFM01; PFM-01; PFM 01. Grades: ≥98% by HPLC. CAS No. 1558598-41-6. Molecular formula: C14H15NO2S2. Mole weight: 293.4. | |
| PFM03 | PFM03 is a MRE11 Endonuclease inhibitor. PFM03 regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1558598-48-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148078. | |
| PFM39 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PFM39 | PFM39, a Mirin analog, is a potent and selective MRE11 exonuclease inhibitor. PFM39 inhibits phosphate rotation for dsDNA exonuclease activity. PFM39 does not inhibit TmMre11 or human MRE11/MRN endonuclease activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1310744-67-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120951. | |
| PFN-B | PFN-B. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-1,4-phenylene]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 673474-79-8. Molecular formula: (C29H34N2)n. Product ID: ACM673474798-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: PFN (Belgium). | |
| PFNBr | PFNBr. Uses: Designed for use in research and industrial production. Product Category: Perovskite Solar Cells. CAS No. 673474-77-6. Product ID: ACM673474776. Alfa Chemistry ISO 9001:2015 Certified. Categories: 889672-99-5, Penbrook, Pennsylvania. | |
| PFN-Br | PFN-Br. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-bis(3'-((N,N-dimethyl)-N-ethylammonium)-propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)]dibromide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 889672-99-5. Molecular formula: (C56H80N2Br2)n. Product ID: ACM889672995. Alfa Chemistry ISO 9001:2015 Certified. Categories: PFC Brestnik 1948. | |
| PFN-diiodine salt | PFN-diiodine salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly{[(9,9-bis[3-(trimethylammonium)propyl-2,7-fluorene)]-alt-2,7-(9,9-dioctylfluorene)}diiodide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1687752-60-8. Molecular formula: (C56H80N2I2)n. Product ID: ACM1687752608-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFN-DOF | Phosphorescent host material. Polymer for use in electron transport layer in OPV and OLED applications. Uses: Phosphorescent host material. polymer for use in electron transport layer in opv and oled applications. Group: Organic light-emitting diode (oled) materials. Alternative Names: Poly[(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)]. CAS No. 673474-75-4. Mole weight: (C52H70N2)n. | |
| PFN-FP-I | PFN-FP-I. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-bis(3'-(N,N-trimethylamino)propyl)-2,7-fluorene)-alt-1,4-phenylene]diiodide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1026670-72-3. Molecular formula: (C31H40I2N2)n. Product ID: ACM1026670723-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFN-OX | PFN-OX. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly{2,7-[9,9-bis(6'-(N,N-diethylamino)hexyl)fluorene]-alt-2,7-[9,9-bis(6-((3-ethyloxetan-3-yl)methoxy)hexyl)fluorene]}. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1345045-27-3. Molecular formula: (C70H102N2O4)nC12H10. Product ID: ACM1345045273. Alfa Chemistry ISO 9001:2015 Certified. Categories: Pano Xhixho. | |
| PFO | PFO. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly(9,9-dioctylfluorenyl-2,7-diyl). Product Category: Organic Light Emitting Diode (OLED). CAS No. 123864-00-6. Molecular formula: (C29H40)n. Product ID: ACM123864006. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFO-BPy | PFO-BPy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-dioctylfluorenyl-2,7-diyl)-alt-(6,6'-{2,2'-bipyridine})]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1423043-97-3. Molecular formula: (C39H46N2)n. Product ID: ACM1423043973-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFODBT | PFODBT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[2,1,3-benzothiadiazole-4,7-diyl-2,5-thiophenediyl(9,9-dioctyl-9H-fluorene-2,7-diyl)-2,5-thiophenediyl];APO3,PFO-DBT;PFTBT. Product Category: Flexible Printed Electronics. CAS No. 782469-77-6. Purity: 95%+. Product ID: ACM782469776-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFO-DBT | PFO-DBT. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. | |
| PFO-DMP | PFO-DMP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly(9,9-dioctylfluorenyl-2,7-diyl) end capped with dimethylphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 874816-14-5. Molecular formula: C16H18(C29H40)n. Product ID: ACM874816145. Alfa Chemistry ISO 9001:2015 Certified. | |
| PFPV | PFPV. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-dioctyl-2,7-divinylenefluorenylene)-alt-{2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene}]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 475101-36-1. Molecular formula: (C48H66O2)n. Product ID: ACM475101361-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: PFP (enzyme). | |
| PFQa-St2 | PFQa-St2 is an antimicrobial peptide found in the African clawed frog Silurana tropicalis, and has anti-gram-positive bacteria, gram-negative bacteria and Mammalian cells activity. Synonyms: Phe-Ile-Gly-Ala-Leu-Leu-Arg-Pro-Ala-Leu-Lys-Leu-Leu-Ala-Gly-Lys. Grades: ≥97%. Molecular formula: C81H141N21O17. Mole weight: 1681.15. | |
| Pfu DNA Polymerase | Pfu DNA Polymerase. Pfu dna polymerase is a fast, high fidelity and high processivity hot start dna polymerase. extension rate is about 2-4 kb/min. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3015. |  |
| PG 01 | PG 01. Group: Biochemicals. Grades: Purified. CAS No. 853138-65-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PG 01 | PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. PG 01 is effective on G970R although with a significant decrease in potency relative to E193K and ΔF508. Synonyms: PG 01; PG-01; PG01; N-Methyl-N-[2-[[4-(1-Methylethyl)phenyl]amino]-2-1H-indole-3-acetamide. Grades: ≥98% by HPLC. CAS No. 853138-65-5. Molecular formula: C28H29N3O2. Mole weight: 439.55. | |
| PG-01 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| PG 01037 dihydrochloride | PG 01037 dihydrochloride is a dopamine D3 receptor antagonist, which is more selective for D3 receptors than other D3 antagonists that are currently available with a D2/D3 selectivity ratio of 867 and a D4/D3 selectivity ratio of 13,000 (Ki values are 0.70, 93.3 and 375 nM for D3, D2 and D4 receptors respectively). Synonyms: N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamide dihydrochloride; PG 01037 dihydrochloride; PG 01037 diHCl; PG 01037; PG01037; PG-01037. Grades: ≥98%. CAS No. 675599-62-9. Molecular formula: C26H26Cl2N4O.2HCl. Mole weight: 554.34. | |
| PG 01037 dihydrochloride | PG 01037 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 675599-62-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PG 106 | PG 106 is a selective human melanocortin receptor 3 (hMC3R) antagonist (IC50 = 210 nM), with no activity at hMC4 receptors and hMC5 receptors. PG 106 may be used to differentiate the substructural features responsible for selectivity at the hMC3R, hMC4R, and hMC5R. Synonyms: PG106; PG-106; Ac-DL-Nle-Asp(1)-bAla-D-2Nal-Arg-Trp-Lys(1)-NH2; N-Acetyl-L-norleucyl-L-α-aspartyl-β-alanyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-Lysinamide(2?7)-lactam; Ac-Nle-cyclo(-Asp-β-Ala-D-2-Nal-Arg-Trp-Lys)-NH2. Grades: >98%. CAS No. 944111-22-2. Molecular formula: C51H69N13O9. Mole weight: 1008.19. | |
| PG 106 | PG 106. Group: Biochemicals. Grades: Purified. CAS No. 944111-22-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| pG(2',5')pA | pG(2',5')pA is a potential metabolite of 2'3'-cGAMP, the metazoan cyclic dinucleotide second messenger. Synonyms: 5'- Phosphoguanylyl- (2' -≥ 5')- adenosine, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 55779-55-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4. | |
| PG 34 | PG 34 is a weak O-GlcNAc transferase ( OGT ) inhibitor ( IC 50 =68 μM), and a close structural analog of OSMI-1 (HY-119738) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1681056-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148113. | |
| PG490-88 | PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47. | |
| PG545 | PG545 is an angiogenesis and heparanase inhibitor, which inhibited the proliferation, migration, and colony formation of pancreatic cancer cells in vitro at pharmacologically relevant concentrations. PG545 significantly prolonged animal survival in intraperitoneal and genetic models (mPDAC: LSL-Kras(G12D); Cdkn2a(lox/lox); p48(Cre)) of PDAC. PG545 also inhibited primary tumor growth and metastasis in orthotopic and genetic endpoint studies. PG545 significantly decreased cell proliferation, increased apoptosis, reduced microvessel density, disrupted vascular function, and elevated intratumoral hypoxia. Synonyms: PG 545; PG-545. CAS No. 1144492-69-2. Molecular formula: C51H75Na13O60S13. Mole weight: 2363.75. | |
| PG 931 | PG 931. Group: Biochemicals. Grades: Purified. CAS No. 667430-81-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PG 931 | PG 931 is a potent and selective melanocortin 4 (MC4) receptor agonist (IC50= 0.58 and 55 nM for human MC4 and MC3 receptors respectively). Synonyms: PG 931; PG931; PG-931; XDPFRWKPV; (2S, Z) -1- ( (1E, 3S, 4Z, 6S, 7Z, 9S, 10Z, 12S, 17E, 20S, 25aS) -9- ( (1H-indol-3-yl) methyl) -3-benzyl-6- (3-guanidinopropyl) -1, 4, 7, 10, 18-pentahydroxy-20- ( (Z) - (1-hydroxy-2- ( (Z) - (1-hydroxyethylidene) amino) hexylidene) amino) -21-oxo-6, 9, 12, 13, 14, 15, 16, 19, 20, 21, 23, 24, 25, 25a-tet. CAS No. 667430-81-1. Molecular formula: C59H85N15O11. Mole weight: 1180.41. | |
| PG-931 | PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor ( IC 50 =0.58 nM) agonist and is more selective than for the hMC3R ( IC 50 =55 nM) or the hMC5R ( IC 50 =2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo [2]. Uses: Scientific research. Group: Peptides. CAS No. 667430-81-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1208. | |
| PG 97-269 | PG 97-269, a selective high affinity VPAC1 receptor antagonist, has negligible affinity for PACAP type I receptors, with Kis of 15±5 and 2±1 nM for the rat and human VPAC1 receptors, respectively. It can be used to evaluate the physiological role of VIP in rats and human tissues. Synonyms: Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27); Ac-His-D-Phe-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2; L-Leucinamide, N-acetyl-L-histidyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-lysyl-L-arginyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-. Grades: ≥95%. CAS No. 202463-00-1. Molecular formula: C150H246N44O38. Mole weight: 3273.83. | |
| PG-9 maleate | PG-9 maleate, derived from (+)-R-hyoscyamine, is a potent analgesic and nootropic agent, which increases release of acetylcholine. Synonyms: PG-9 maleate; PG 9 maleate; PG9 maleate; Tropanyl 2-(4-bromophenyl)propionate maleate. CAS No. 155649-00-6. Molecular formula: C17H22BrNO2.C4H4O4. Mole weight: 468.34. | |
| PG-9 maleate | PG-9 maleate. Group: Biochemicals. Grades: Purified. CAS No. 155649-00-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PgAFP | PgAFP is an antimicrobial peptide found in Penicillium chrysogenum RP42C (Penicillium notatum), and has antifungal activity. Synonyms: Antifungal protein; afp. Grades: >98%. Molecular formula: C272H431N89O85S6. Mole weight: 6500.32. | |
| Pg-AMP1 | Pg-AMP1 is an antimicrobial peptide found in Psidium guajava (Guava, Psidium pyriferum), and has anti-gram-positive bacteria and gram-negative bacteria activity. Synonyms: Glycine-rich antimicrobial peptide Pg-AMP. Grades: >98%. Mole weight: 6029.00. | |
| PGD2-IN-1 | PGD2-IN-1 is an antagonist of DP (IC50 = 0.3 nM). Synonyms: MDK66671; MDK-66671 MDK 66671; PGD2-IN-1; PGD2 IN 1; 2-[3-[6-[2-(2,4-dichlorophenyl)ethylamino]-2-methoxypyrimidin-4-yl]phenyl]-2-methylpropanoic acid. CAS No. 885066-67-1. Molecular formula: C23H23Cl2N3O3. Mole weight: 460.35. | |
| Pge2,[5,6,8,11,12,14,15-3h] | Pge2,[5,6,8,11,12,14,15-3h]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [5,6,8,11,12,14,15(N)-3H]-PROSTAGLANDIN E2;PGE2, [5,6,8,11,12,14,15-3H];PROSTAGLANDIN E2, [5,6,8,11,12,14,15-3H];PROSTAGLANDIN E2-[5,6,8,11,12,14,15-3H(N)]. Product Category: Heterocyclic Organic Compound. CAS No. 84807-93-2. Molecular formula: C20H25O5T7. Mole weight: 366.52. Product ID: ACM84807932. Alfa Chemistry ISO 9001:2015 Certified. | |
| PG-KI | PG-KI is an antimicrobial peptide found in Pseudophryne guentheri (Australian myobatrachid frog, Guenther's toadlet), and has antimicrobial activity. Synonyms: pGlu-Pro-His-Pro-Asp-Glu-Phe-Val-Gly-Leu-Met-NH2; Kassinin-Like Peptide K-I; Recombinant Pseudophryne guentheri Kassinin-like peptide K-I. Grades: ≥97%. Molecular formula: C57H82N14O16S. Mole weight: 1251.43. | |
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