American Chemical Suppliers
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Product | Description | |
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PF 915275 Quick inquiry Where to buy Suppliers range | PF 915275. Group: Biochemicals. Grades: Purified. CAS No. 857290-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
PF 915275 Quick inquiry Where to buy Suppliers range | PF-915275 is a selective and potent and inhibitor of human 11β-hydroxysteroid dehydrogenase type 1(11βHSD1) inhibitor with Ki 2.3 nM. It has good preclinical pharmacokinetic properties. It inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro and has antidiabetic activity in vivo. It maintains potency in our cellular assay against human 11βHSD1 and is selective against human 11βHSD2 in vitro. It displays only weak affinity for the rodent choline transporter (Ki = 9.6 μM) and the hamster melatonin MT3 receptor (Ki = 9.6 μM) in the Cerep Bioprint screening panel. It has good in vitro pharmacokinetic properties. It has low clearance and high permeability. It has an excellent pharmacokinetic profile characterized by low clearance, long half-life and good oral bioavailability. Uses: Pf-915275 inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro and has antidiabetic activity in vivo. it has an excellent pharmacokinetic profile characterized by low clearance, long half-life and good oral bioavailability. Synonyms: PF-915275; PF 915275; PF915275; N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide;N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide;[1,1'-Bip;4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide. Grades: >98 %. CAS No. 857290-04-1. Molecular formula: C18H14N4O2S. Mole weight: 350.39. | |
PF 9184 Quick inquiry Where to buy Suppliers range | This active molecular is selective mPGES-1 (microsomal prostaglandin E synthase-1 inhibitor. mPGES-1 is an enzyme induced during the inflammatory response and it is for developing anti-inflammatory drugs. PF-9184 inhibited recombinant human mPGES-1 with IC50 value of 16.5nM. PF-9184 had no effect against COX-1 and COX-2 with more than 6500-fold selectivity. PF-9184 inhibited PGE(2) synthesis with IC50 value in the range of 0.5-5 mM in serum-free cell and human whole blood cultures. Uses: Anti-inflammatory agent. Synonyms: N-(3',4'-Dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide. Grades: 98%. CAS No. 1221971-47-6. Molecular formula: C21H14Cl2N2O4S. Mole weight: 461.31. | |
PF 945863 Quick inquiry Where to buy Suppliers range | PF 945863, an orally active macrolide antibiotic, is active against multidrug resistant respiratory tract bacterial strains. Synonyms: PF 945863; PF945863; PF-945863; (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-[1-[(1R)-1-(1,8-naphthyridin-4-yl)ethyl]-3-azetidinyl]-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)tetrone. Grades: ≥98% by HPLC. CAS No. 893556-85-9. Molecular formula: C44H65N5O10. Mole weight: 824.01. | |
PF-956980 Quick inquiry Where to buy Suppliers range | PF-956980, a close analogue of Tofacitinib, is a JAK3-selective inhibitor used as an anti-inflammatory agent. Besides, some studies showed that PF-956980 strikingly reversed the cytoprotective action of IL-4 on CLL cells. Synonyms: PF-956980; PF 956980; PF956980; Methanone, [(3R,?4R)?-4-methyl-3-(methyl-7H-pyrrolo[2,?3-d]?pyrimidin-4-ylamino)?-1-piperidinyl]?-1-pyrrolidinyl-. CAS No. 1262832-74-5. Molecular formula: C18H26N6O. Mole weight: 342.44. | |
PF-956980 Hydrate Quick inquiry Where to buy Suppliers range | PF-956980 is a FGF1 receptor antagonist; PDGF receptor modulator; Flt3 tyrosine kinase modulator; and VEGF antagonist. PF-956980 is used as immunosuppressive agent. Group: Biochemicals. Alternative Names: [(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-1-pyrrolidinylmethanone Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
PF9601N, 98% Quick inquiry Where to buy Suppliers range | PF9601N, 98%. Group: Pathway Inhibitors. CAS No. 133845-63-3. Pack Sizes: 5mg. ID EBT1038. | |
PF 998425 Quick inquiry Where to buy Suppliers range | PF 998425 is a novel, nonsteroidal androgen receptor (AR) antagonist (IC50= 26 nM and 90 nM in AR binding assays and cellular assays respectively) for sebum control and treatment of androgenetic alopecia. It is potent, selective, and active in vivo. PF 998425 exhibits low affinity for progesterone receptor (IC50 > 10 μM). Uses: Androgen receptor antagonists. Synonyms: 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile; PF0998425; PF 0998425; PF-0998425. Grades: ≥98% by HPLC. CAS No. 1076225-27-8. Molecular formula: C14H14F3NO. Mole weight: 269.26. | |
PF-998425 Quick inquiry Where to buy Suppliers range | PF-998425 is a novel, nonsteroidal androgen receptor antagonist for sebum control and treatment of androgenetic alopecia. Group: Biochemicals. Alternative Names: rel- (-) -4-[ (1R, 2R) -2-Hydroxycyclohexyl]-2- (trifluoromethyl) benzonitrile. Grades: Highly Purified. CAS No. 1076225-27-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
PF9 tetrasodium salt Quick inquiry Where to buy Suppliers range | PF9 tetrasodium salt is an activator of GPR17 (EC50 = 36 pM). Synonyms: PF9 tetrasodium salt; PF 9 tetrasodium salt; PF-9 tetrasodium salt; 2-(Phenylethynyl)adenosine-5'-triphosphate tetrasodium salt. Grades: ≥98% by HPLC. CAS No. 851265-78-6. Molecular formula: C18H16N5Na4O13P3. Mole weight: 695.23. | |
PF9 tetrasodium salt Quick inquiry Where to buy Suppliers range | PF9 tetrasodium salt. Group: Biochemicals. Grades: Purified. CAS No. 851265-78-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
PF-AKT400 Quick inquiry Where to buy Suppliers range | PF-AKT400 is an APT competitor inhibitor of AKR kinase. This compound was first described as compound 42 in J. Med. Chem. 2010, 53, 4615-4622 by a group of Pfizer scientists. The paper describes the design and synthesis of novel, ATP-competitive Akt inhibitors from an elaborated 3-aminopyrrolidine scaffold. Key findings include the discovery of an initial lead that was modestly selective and medicinal chemistry optimization of that lead to provide more selective analogues. Analysis of the data suggested that highly lipophilic analogues would likely suffer from poor overall properties. Central to the discussion is the concept of optimization of lipophilic efficiency and the ability to balance overall druglike propeties with the careful control of lipophilicity in the lead series. Discovery of the nonracemic amide series and subsequent modification produced an advanced analogue that performed well in advanced preclinical assays, including xenograft tumor growth inhibition studies, and this analogue was nominated for clinical development. The compound has no official name, has molecule weight 400.43. We temporally call this compound as PF-AKT400. Synonyms: PF-AKT400; PFAKT400; Lig1; Lig-1; Lig 1; PF AKT400; AKT-0286; AKT 0286; AKT0286. CAS No. 1004990-28-6. Molecular formula: C20H22F2N6O. Mole weight: 400.43. | |
PF-CBP1 Quick inquiry Where to buy Suppliers range | PF-CBP1, also known as PF-06670910, is a selective CBP/p300 bromodomain inhibitor (IC50 values are 125 and 363 nM, respectively) with >100-fold selectivity for CBP over BRD4. Also, PF-CBP1 significantly reduces levels of RGS4 mRNA levels in neurons. Synonyms: 4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine; PF-CBP1; PF-CBP-1; PF-CBP 1; PF-06670910; PF 06670910; PF06670910.PF-CBP1; PF CBP1; PFCBP1. CAS No. 1962928-21-7. Molecular formula: C29H36N4O3. Mole weight: 488.63. | |
PF-CBP1 HCl Quick inquiry Where to buy Suppliers range | PF-CBP1, also known as PF-06670910, is an inhibitor of the CBP and p300 bromodomains (IC50s = 125 and 363 nM, respectively) with more than 100-fold selectivity for the bromodomain of CBP over those of BRD4 and a panel of other proteins. Also, PF-CBP1 significantly reduces levels of RGS4 mRNA levels in neurons. Synonyms: 4-(2-(5-(3,5-Dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine hydrochloride; PF-CBP1 HCl; PF-CBP1; hydrochloride; PF-CBP1; PF-CBP-1; PF-CBP 1; PF-06670910; PF 06670910; PF06670910. CAS No. 2070014-93-4. Molecular formula: C29H37ClN4O3. Mole weight: 525.09. | |
PFD Quick inquiry Where to buy Suppliers range | PFD. Group: Flexible Printed Electronics. Alternative Names: Poly(9,9-di-n-dodecylfluorene). CAS No. 248256-53-3. | |
PF-DMB Quick inquiry Where to buy Suppliers range | PF-DMB. Group: Flexible Printed Electronics. Alternative Names: PF-DMB;Poly[(9,9-dihexylfluoren-2,7-diyl)-alt-(2,5-dimethyl-1,4-phenylene)]. Grades: 96%. CAS No. 579505-48-9. | |
PFE-360 Quick inquiry Where to buy Suppliers range | PFE-360 Inhibitor. Uses: Scientific use. Product Category: T16512. CAS No. 1527475-61-1. | |
PffBT4T-2OD Quick inquiry Where to buy Suppliers range | PffBT4T-2OD. CAS No. 1644164-62-4. | |
PffBT4T-C9C13 Quick inquiry Where to buy Suppliers range | PffBT4T-C9C13. Group: Organic Field Effect Transistor (OFET) Materials; Organic Solar Cell (OPV) Materials. | |
PFI-1 Quick inquiry Where to buy Suppliers range | PFI-1. Group: Biochemicals. Alternative Names: 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide; 2-Methoxy-N- (1, 2, 3, 4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 1403764-72-6. Pack Sizes: 5mg. Molecular Formula: C16H17N3O4S, Molecular Weight: 347.39. US Biological Life Sciences. | Worldwide |
PFI-1 Quick inquiry Where to buy Suppliers range | PFI-1 is a potent and highly selective protein interaction Inhibitor, which targets BET bromodomain. PFI-1 that efficiently blocks the interaction of BET BRDs with acetylated histone tails. Co-crystal structures showed that PFI-1 acts as an acetyl-lysine (Kac) mimetic inhibitor efficiently occupying the Kac binding site in BRD4 and BRD2. PFI-1 has antiproliferative effects on leukaemic cell lines and efficiently abrogates their clonogenic growth. Exposure of sensitive cell lines with PFI-1 results in G1 cell cycle arrest, down-regulation of MYC expression as well as induction of apoptosis and induces differentiation of primary leukaemic blasts. Intriguingly, cells exposed to PFI-1 showed significant down-regulation of Aurora B kinase, thus attenuating phosphorylation of the Aurora substrate H3S10 providing an alternative strategy for the specific inhibition of this well established oncology target. Synonyms: PFI1; PFI 1; PFI-1. CAS No. 1403764-72-6. Molecular formula: C16H17N3O4S. Mole weight: 347.39. | |
PFI-2 Quick inquiry Where to buy Suppliers range | PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. Synonyms: PFI-2; PFI 2; PFI2. Grades: >98%. CAS No. 1627676-59-8. Molecular formula: C23H25F4N3O3S. Mole weight: 499.52. | |
PFI-2 hydrochloride Quick inquiry Where to buy Suppliers range | PFI-2 hydrochloride is a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM) and is approximately 1,000-fold selective over a panel of 18 other methyltransferases. Besides, following activation of the Hippo signaling pathway in MCF7 cells it inhibits. Synonyms: PFI-2 hydrochloride; PFI 2 hydrochloride; PFI2 hydrochloride; 8-fluoro-N-[(2R)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride. CAS No. 1627607-87-7. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.98. | |
PFI-3 Quick inquiry Where to buy Suppliers range | PFI-3, a potent and selective SMARCA2/4 bromodomain inhibitor, is a cell-permeable probe that binds avidly to the structurally-similar SMARCA4 bromodomain (Kd= 89 nM) and PB1(bromodomain 5) (Kd= 48 nM). Synonyms: PFI-3; PFI 3; PFI3. (E)-1-(2-hyd roxyphenyl)-3-[(1R,4R)-2-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-5-yl]prop-2-en-1-one; PF-06687252; PFI-3 compound; PF 06687252; PF06687252. Grades: >98%. CAS No. 1819363-80-8. Molecular formula: C19H19N3O2. Mole weight: 321.38. | |
PFI-4 Quick inquiry Where to buy Suppliers range | PFI-4 is a potent and selective BRPF1 bromodomain inhibitor with IC50 of 80 nM. Synonyms: PFI-4; PFI 4; PFI4. Grades: 98%. CAS No. 900305-37-5. Molecular formula: C21H24N4O3. Mole weight: 380.44. | |
PFK15 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 4382-63-2. Pack Sizes: 5MG, 25MG. Mole weight: 260.29. Catalog: AP4382632. Assay: ≥98% (HPLC). | |
PFK15 Quick inquiry Where to buy Suppliers range | PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment. Synonyms: PFK 015; PFK015; 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one. Grades: >98%. CAS No. 4382-63-2. Molecular formula: C17H12N2O. Mole weight: 260.29. | |
PFK-158 Quick inquiry Where to buy Suppliers range | PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. PFKFB3, an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-2,6-bisphosphate, is highly expressed and active in human cancer cells; it plays a key role in increasing both glycolytic flux in and proliferation of cancer cells. Synonyms: PFK158; PFK 158; PFK158; ACTPFK158. Grades: >98%. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. | |
PFKFB3 Inhibitor, 3PO (6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Inhibitor, 3PO, 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, (2E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one) Quick inquiry Where to buy Suppliers range | A cell-permeable dipyridinyl-propenone compound that selectively blocks PFK-2 (6-phosphofructo-2-kinase) activity of PFKFB3 isozyme over PFK-1 (6-phosphofructo-1-kinase) in a mixed-mode manner. Rapidly decreases fructose-2,6-bisphosphate (F-2,6-P2) and 2-deoxyglucose uptake, and lactate secretion; efficiently arrests proliferation of transformed cells (IC50 ~1.4uM in NHBE-ht/LT/ras) and suppresses tumor growth in several xenograft mouse models (70mg/kg, i.p.). The cytostatic and cytotoxic effects of 3PO is shown to be highly sensitive to the intracellular levels of F-6-P (fructose-6-phosphate) and F-2,6-P2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
p-Fluoro-a-acetamidocinnamic Acid Quick inquiry Where to buy Suppliers range | p-Fluoro-a-acetamidocinnamic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
p-Fluoro-alpha-acetamidocinnamic acid Quick inquiry Where to buy Suppliers range | 2-acetamido-3-(4-fluorophenyl)prop-2-enoic Acid, p-Fluoro-alpha-acetamidocinnamic Acid, 111649-72-0, p-fluoroacetaminocinnamic acid, AKOS030240118, FT-0668600, p-Fluoro-|A-acetamidocinnamic Acid, (Z)-2-acetamido-3-(4-fluorophenyl)prop-2-enoic acid, p-Fluoro-alpha-acetamidocinnamic Acid, 111649-72-0, SCHEMBL8652648, AKOS001642700, p-Fluoro- alpha -acetamidocinnamic Acid, 4-Fluoro-alpha-(acetylamino)cinnamic acid, SR-01000466897, J-002611, N-Acetyl-alpha,beta-didehydro-4-fluorophenylalanine, SR-01000466897-1, (2Z)-2-(acetylamino)-3-(4-fluorophenyl)acrylic acid. | |
p-Fluorobenzyl Chloride Quick inquiry Where to buy Suppliers range | p-Fluorobenzyl Chloride. Group: Biochemicals. Alternative Names: α-Chloro-4-fluorotoluene; α-Chloro-p-fluorotoluene; 1-(Chloromethyl)-4-fluorobenzene; 4-Fluorobenzyl Chloride; 4-Fluorophenylmethyl Chloride; NSC 25084; 1-(Chloromethyl)-4-fluorobenzene. Grades: Highly Purified. CAS No. 352-11-4. Pack Sizes: 10g. Molecular Formula: C7H6ClF, Molecular Weight: 144.57. US Biological Life Sciences. | Worldwide |
p-Fluorophenyl-2-thienylketone Quick inquiry Where to buy Suppliers range | p-Fluorophenyl-2-thienylketone. Group: Biochemicals. Alternative Names: (4-Fluorophenyl)-2-thienylmethanone. Grades: Highly Purified. CAS No. 579-49-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
p-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | Intermediate in the synthesis of p-Fluoro Prasugrel (F595875). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(4-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
p-Fluoropropiophenone Quick inquiry Where to buy Suppliers range | p-Fluoropropiophenone. Group: Biochemicals. Grades: Highly Purified. CAS No. 456-03-1. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
p-Fluorostyrene Quick inquiry Where to buy Suppliers range | p-Fluorostyrene. Group: Polymer/Macromolecule. Alternative Names: 4-Fluorostyrene, 97%, stabilized; AS03795; ST2403438; RTR-033260; 4-Fluorostyrene, 99%; AN-44804; 405-99-2; ACN-S004611; CTK3J0456; I01-7785. CAS No. 405-99-2. Molecular formula: C8H7F. Mole weight: 122.142g/mol. IUPAC Name: 1-ethenyl-4-fluorobenzene. Rotatable Bond Count: 1. Exact Mass: 122.053g/mol. EC Number: 206-975-0. Melting Point: -34.5°C. SMILES: C=CC1=CC=C(C=C1)F. InChI: InChI=1S/C8H7F/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2. InChIKey: JWVTWJNGILGLAT-UHFFFAOYSA-N. H-Bond Acceptor: 1. Monoisotopic Mass: 122.053g/mol. | |
PFM 01 Quick inquiry Where to buy Suppliers range | PFM 01, a cell-permeable N-alkylated Mirin derivative, is a nuclease-specific MRE11 inhibitor, which enhances non-homologous end-joining (NHEJ) and reduces homologous recombination. Synonyms: (5Z)-5-[(4-Hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone; PFM01; PFM-01; PFM 01. Grades: ≥98% by HPLC. CAS No. 1558598-41-6. Molecular formula: C14H15NO2S2. Mole weight: 293.4. | |
PFN-Br Quick inquiry Where to buy Suppliers range | PFN-Br is a solution processible, conjugated polymer electrolyte used as interficial layer in high performance organic photovoltaic cells (OPV) and organic light emitting diodes (OLED) to improve the interfacial properties. OPV devices with PFN-Br interfacial layer showed overall enhanced short-circuit current density, open-circuit voltage, fill factor and corresponding high efficiency in the inverted OPVs.[3] This was attributed to the good contact between ZnO electron extraction layer and the active layer, good interface adhesion between the electron extraction layer and active layer, and enhanced charge transport via suppressed bimolecular recombination. Recent report of OPV with a record energy conversion efficiency of 17.3% also utilized PFN-Br, spin-coated on top of ZnO to improve the interfacial properties. Tandem Cell Device performance: ITO/ZnO/PFN-Br/PBDB-T:F-M/M-PEDOT/ZnO/PTB7- Th:O6T-4F:PC71BM/MoO3/Ag Voc=1.642 V Jsc=14.35 mA/cm2 FF=73.7% PCE=17.3% PFN-Br finds application in a wide range of areas: OPV interficial layer (metalic oxide compact layer) OLED electron transport layer Perovskite solar cells Flexible printed electronics Cationic polymer electrolyte Anion exchange material Light emitting electrochemical cells. Group: Photoactive Polymers. Alternative Names: OS0995, PFN-P2, Poly(9,9-bis(3'-(N,N-dimethyl)-N-ethylammoinium-propyl-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene))dibromide. CAS No. 889672-99-5. Product ID: ACM889672995. Appearance: beige to yellow solid. | |
PFNBr Quick inquiry Where to buy Suppliers range | PFNBr. Group: Perovskite Solar Cells. CAS No. 673474-77-6. | |
PFN-DOF Quick inquiry Where to buy Suppliers range | solid. Group: Perovskite Solar Cells. Alternative Names: Poly[(9,9-bis(3'-(N,N-dimethylamino)propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluorene)]. CAS No. 673474-75-4. | |
PFN-FP Quick inquiry Where to buy Suppliers range | PFN-FP is a precursor to alcohol and water-soluble polymer for optoelectronic applications. Blue Emitter (410 nm in THF) for OLED and other applications. Ionic derivatives PFN-FP-I is also available (SOL2414). Custom counter ions can be substituted to make this polymer water-soluble. Group: Polymer. CAS No. 673474-79-8. Molecular Weight: 20-50 kDa. | |
PFN-FP-I Quick inquiry Where to buy Suppliers range | PFN-FP-I is a water and alcohol soluble polymer for optoelectronic applications. Blue Emitter (410 nm in THF) for OLED and other applications. The free base is also available PFN-FP (SOL2423). Custom counter ions can be substituted. Group: Polymer. CAS No. 1026670-72-3. Molecular Weight: 15-50 kDa. | |
PFN-OX Quick inquiry Where to buy Suppliers range | PFN-OX. Group: Organic Light Emitting Diode (OLED). CAS No. 1345045-27-3. | |
PFO Quick inquiry Where to buy Suppliers range | PFO. Group: Flexible Printed Electronics. CAS No. 123864-00-6. | |
PFO-DBT Quick inquiry Where to buy Suppliers range | PFO-DBT. Group: Organic Field Effect Transistor (OFET) Materials; Organic Solar Cell (OPV) Materials. | |
PFODBT Quick inquiry Where to buy Suppliers range | PFODBT. Group: Flexible Printed Electronics. CAS No. 782469-77-6. | |
PFO-DMP Quick inquiry Where to buy Suppliers range | PFO-DMP. Group: Flexible Printed Electronics. CAS No. 874816-14-5. | |
PFQa-St2 Quick inquiry Where to buy Suppliers range | PFQa-St2 is an antimicrobial peptide found in the African clawed frog Silurana tropicalis, and has anti-gram-positive bacteria, gram-negative bacteria and Mammalian cells activity. Synonyms: Phe-Ile-Gly-Ala-Leu-Leu-Arg-Pro-Ala-Leu-Lys-Leu-Leu-Ala-Gly-Lys. Grades: ≥97%. Molecular formula: C81H141N21O17. Mole weight: 1681.15. | |
PFQa-St2 Quick inquiry Where to buy Suppliers range | PFQa-St2. Uses: Antimicrobial Peptides. Product ID: AF446. | |
PG 01 Quick inquiry Where to buy Suppliers range | PG 01. Group: Biochemicals. Grades: Purified. CAS No. 853138-65-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
PG 01 Quick inquiry Where to buy Suppliers range | PG 01 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. PG 01 is effective on G970R although with a significant decrease in potency relative to E193K and ΔF508. Synonyms: PG 01; PG-01; PG01; N-Methyl-N-[2-[[4-(1-Methylethyl)phenyl]amino]-2-1H-indole-3-acetamide. Grades: ≥98% by HPLC. CAS No. 853138-65-5. Molecular formula: C28H29N3O2. Mole weight: 439.55. | |
PG 01037 dihydrochloride Quick inquiry Where to buy Suppliers range | PG 01037 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 675599-62-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
PG 01037 dihydrochloride Quick inquiry Where to buy Suppliers range | PG 01037 dihydrochloride is a dopamine D3 receptor antagonist, which is more selective for D3 receptors than other D3 antagonists that are currently available with a D2/D3 selectivity ratio of 867 and a D4/D3 selectivity ratio of 13,000 (Ki values are 0.70, 93.3 and 375 nM for D3, D2 and D4 receptors respectively). Synonyms: N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamide dihydrochloride; PG 01037 dihydrochloride; PG 01037 diHCl; PG 01037; PG01037; PG-01037. Grades: ≥98%. CAS No. 675599-62-9. Molecular formula: C26H26Cl2N4O.2HCl. Mole weight: 554.34. | |
PG 106 Quick inquiry Where to buy Suppliers range | PG 106. Group: Biochemicals. Grades: Purified. CAS No. 944111-22-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
PG 106 Quick inquiry Where to buy Suppliers range | PG 106 is a selective human melanocortin receptor 3 (hMC3R) antagonist (IC50 = 210 nM), with no activity at hMC4 receptors and hMC5 receptors. PG 106 may be used to differentiate the substructural features responsible for selectivity at the hMC3R, hMC4R, and hMC5R. Synonyms: PG106; PG-106; Ac-DL-Nle-Asp(1)-bAla-D-2Nal-Arg-Trp-Lys(1)-NH2; N-Acetyl-L-norleucyl-L-α-aspartyl-β-alanyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-Lysinamide(2?7)-lactam; Ac-Nle-cyclo(-Asp-β-Ala-D-2-Nal-Arg-Trp-Lys)-NH2. Grades: >98%. CAS No. 944111-22-2. Molecular formula: C51H69N13O9. Mole weight: 1008.19. | |
PG 106 Quick inquiry Where to buy Suppliers range | PG 106 is a selective antagonist of human melanocortin receptor 3 (hMC3R), and shows no activity at hMC4 receptors and hMC5 receptors. Therefore, it may be used to differentiate the substructural features responsible for selectivity at the hMC3R, hMC4R, and hMC5R. Uses: Peptide Inhibitors. CAS No. 944111-22-2. Product ID: R0980. | |
pG(2',5')pA Quick inquiry Where to buy Suppliers range | pG(2',5')pA is a potential metabolite of 2'3'-cGAMP, the metazoan cyclic dinucleotide second messenger. Synonyms: 5'- Phosphoguanylyl- (2' -≥ 5')- adenosine, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 55779-55-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4. | |
PG490-88 Quick inquiry Where to buy Suppliers range | PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47. | |
PG545 Quick inquiry Where to buy Suppliers range | PG545 is an angiogenesis and heparanase inhibitor, which inhibited the proliferation, migration, and colony formation of pancreatic cancer cells in vitro at pharmacologically relevant concentrations. PG545 significantly prolonged animal survival in intraperitoneal and genetic models (mPDAC: LSL-Kras(G12D); Cdkn2a(lox/lox); p48(Cre)) of PDAC. PG545 also inhibited primary tumor growth and metastasis in orthotopic and genetic endpoint studies. PG545 significantly decreased cell proliferation, increased apoptosis, reduced microvessel density, disrupted vascular function, and elevated intratumoral hypoxia. Synonyms: PG 545; PG-545. CAS No. 1144492-69-2. Molecular formula: C51H75Na13O60S13. Mole weight: 2363.75. | |
PG 931 Quick inquiry Where to buy Suppliers range | PG 931. Group: Biochemicals. Grades: Purified. CAS No. 667430-81-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
PG 931 Quick inquiry Where to buy Suppliers range | PG 931 is a potent and selective melanocortin 4 (MC4) receptor agonist (IC50= 0.58 and 55 nM for human MC4 and MC3 receptors respectively). Synonyms: PG 931; PG931; PG-931; XDPFRWKPV; (2S, Z) -1- ( (1E, 3S, 4Z, 6S, 7Z, 9S, 10Z, 12S, 17E, 20S, 25aS) -9- ( (1H-indol-3-yl) methyl) -3-benzyl-6- (3-guanidinopropyl) -1, 4, 7, 10, 18-pentahydroxy-20- ( (Z) - (1-hydroxy-2- ( (Z) - (1-hydroxyethylidene) amino) hexylidene) amino) -21-oxo-6, 9, 12, 13, 14, 15, 16, 19, 20, 21, 23, 24, 25, 25a-tet. CAS No. 667430-81-1. Molecular formula: C59H85N15O11. Mole weight: 1180.41. | |
PG 97-269 Quick inquiry Where to buy Suppliers range | PG 97-269, a selective high affinity VPAC1 receptor antagonist, has negligible affinity for PACAP type I receptors, with Kis of 15±5 and 2±1 nM for the rat and human VPAC1 receptors, respectively. It can be used to evaluate the physiological role of VIP in rats and human tissues. Synonyms: Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27); Ac-His-D-Phe-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2; L-Leucinamide, N-acetyl-L-histidyl-D-phenylalanyl-L-α-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-lysyl-L-arginyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-. Grades: ≥95%. CAS No. 202463-00-1. Molecular formula: C150H246N44O38. Mole weight: 3273.83. | |
PG-9 maleate Quick inquiry Where to buy Suppliers range | PG-9 maleate, derived from (+)-R-hyoscyamine, is a potent analgesic and nootropic agent, which increases release of acetylcholine. Synonyms: PG-9 maleate; PG 9 maleate; PG9 maleate; Tropanyl 2-(4-bromophenyl)propionate maleate. CAS No. 155649-00-6. Molecular formula: C17H22BrNO2.C4H4O4. Mole weight: 468.34. | |
PG-9 maleate Quick inquiry Where to buy Suppliers range | PG-9 maleate. Group: Biochemicals. Grades: Purified. CAS No. 155649-00-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
PgAFP Quick inquiry Where to buy Suppliers range | PgAFP is an antimicrobial peptide found in Penicillium chrysogenum RP42C (Penicillium notatum), and has antifungal activity. Synonyms: Antifungal protein; afp. Grades: >98%. Molecular formula: C272H431N89O85S6. Mole weight: 6500.32. | |
PgAFP Quick inquiry Where to buy Suppliers range | PgAFP. Uses: Antimicrobial Peptides. Product ID: AF3325. | |
Pg-AMP1 Quick inquiry Where to buy Suppliers range | Pg-AMP1. Uses: Antimicrobial Peptides. Product ID: AF3313. | |
Pg-AMP1 Quick inquiry Where to buy Suppliers range | Pg-AMP1 is an antimicrobial peptide found in Psidium guajava (Guava, Psidium pyriferum), and has anti-gram-positive bacteria and gram-negative bacteria activity. Synonyms: Glycine-rich antimicrobial peptide Pg-AMP. Grades: >98%. Mole weight: 6029.00. | |
PGD2-IN-1 Quick inquiry Where to buy Suppliers range | PGD2-IN-1 is an antagonist of DP (IC50 = 0.3 nM). Synonyms: MDK66671; MDK-66671 MDK 66671; PGD2-IN-1; PGD2 IN 1; 2-[3-[6-[2-(2,4-dichlorophenyl)ethylamino]-2-methoxypyrimidin-4-yl]phenyl]-2-methylpropanoic acid. CAS No. 885066-67-1. Molecular formula: C23H23Cl2N3O3. Mole weight: 460.35. | |
PG-Dimonium Chloride Phosphate Quick inquiry Where to buy Suppliers range | PG-Dimonium Chloride Phosphate is a chemical compound that is commonly used in personal care and cosmetic products as a conditioning agent. It is a Quaternary Ammonium Compound (QAC) that is derived from phosphoric acid and is positively charged, which makes it attracted to negatively charged surfaces. In personal care products, PG-Dimonium Chloride Phosphate can be used as an emulsifier, a preservative, a viscosity controlling agent, and a hair conditioning agent. It is especially effective in hair care products aimed at reducing frizz, making hair easier to comb and style, and adding shine. Uses: 1. PG-Dimonium Chloride Phosphate is commonly used as an emulsifier in various cosmetic products. 2. It is effective in improving the texture and emollience of the products, making them more pleasant to use. 3. It also helps to stabilize and thicken formulations. 4. PG-Dimonium Chloride Phosphate has antimicrobial properties, making it useful in maintaining the microbiological stability of cosmetic products. 5. It is often used in hair conditioners and shampoos, as it helps to improve the manageability and appearance of hair. 6. PG-Dimonium Chloride Phosphate may also have some anti-inflammatory properties, making it useful for soothing and improving the condition of the skin. Group: Sensory Modifiers. Product ID: ACMA00029416. Appearance: white, odorless powder with a crystalline appearance. |