American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
Product | Description | |
---|---|---|
PETROMYZONOL Quick inquiry Where to buy Suppliers range | Petromyzonol, 28979-29-5, 5alpha-Cholane-3alpha,7alpha,12alpha,24-tetrol, (3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, 5alpha-Cholan-3alpha,7alpha,12alpha,24-tetrol, Cholane-3,7,12,24-tetrol, (3alpha,5alpha,7alpha,12alpha)-, SCHEMBL9697393, CHEBI:50108, HMS3649N19, 5a-cholan-3a,7a,12a,24-tetrol, LMST04010301, AKOS025213187, SR-01000946683, SR-01000946683-1, 3alpha,7alpha,12alpha,24-tetrahydroxy-5alpha-cholane, 5-alpha-cholan-3-alpha,7-alpha,12-alpha,24 tetrol, Q27121909. | |
Petromyzonol 24 Hemisuccinate Quick inquiry Where to buy Suppliers range | Petromyzonol 24 Hemisuccinate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
PETROMYZONOL 24 HEMISUCCINATE Quick inquiry Where to buy Suppliers range | PETROMYZONOL 24 HEMISUCCINATE. | |
Petromyzonol-24-Sulfate, Sodium Salt (PZS) Quick inquiry Where to buy Suppliers range | Petromyzonol sulfate (PZS) is a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). PZS appears to be a spawning chemoattractant for the sea lamprey. Group: Biochemicals. Alternative Names: PZS. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Petromyzonol-3,7,12,21-tetrasulfate Quick inquiry Where to buy Suppliers range | A bile salt derivative isolated from the sea la. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
PETROMYZONOL-3,7,12,21-TETRASULFATE Quick inquiry Where to buy Suppliers range | PETROMYZONOL 3,7,12,21 TETRASULFATE. CAS No. 384342-62-5. | |
Petromyzonol (5-a-Cholane-3-a,7-a,12-a,24-tetrol) Quick inquiry Where to buy Suppliers range | Petromyzonol sulfate (PZS) is a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). PZS appears to be a spawning chemoattractant for the sea lamprey. Group: Biochemicals. Alternative Names: 5-a-Cholane-3-a,7-a,12-a,24-tetrol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Petro Resin Quick inquiry Where to buy Suppliers range | Petro Resin. Group: Polymers. | |
Petroselaidyl Methane Sulfate Quick inquiry Where to buy Suppliers range | Petroselaidyl Methane Sulfate. Grades: 99%+. Product ID: ACMA00017916. Molecular formula: C19H34O3S. Mole weight: 342.54. | |
Petroselinic acid Quick inquiry Where to buy Suppliers range | ≥99%, powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 593-39-5. Pack Sizes: 100MG, 1G. Mole weight: 282.46. EC Number: 209-789-8. Catalog: AP593395. Assay: ≥99%. | |
Petroselinic acid sodium salt Quick inquiry Where to buy Suppliers range | ~98%. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 6697-77-4. Pack Sizes: 100MG. Mole weight: 304.44. Catalog: AP6697774. Assay: ~98%. Linear Formula: C18H33O2Na. | |
Petroselinyl Methane Sulfate Quick inquiry Where to buy Suppliers range | Petroselinyl Methane Sulfate. Grades: 99%+. Product ID: ACMA00003911. Molecular formula: C19H38O3S. Mole weight: 346.57. | |
PET Sirop Bottles Quick inquiry Where to buy Suppliers range | PET Sirop Bottles. Uses: Used for research and manufacturing. Group: Packaging Materials. Product ID: PM-043. | |
PET Substrate Nb2C MXene Quick inquiry Where to buy Suppliers range | We perfectly assembled the monolayer Nb2C Mxene on the PET substrate. Size and craftsmanship can be customized. Uses: Energy storage, catalysis, analytical chemistry, mechanics, adsorption, biology, microelectronics, sensors, etc. Group: MXene Film and Heterojunction. CAS No. 12011-99-3. Flash Point: 0.99. | |
PET Substrate Ti3C2 MXene Quick inquiry Where to buy Suppliers range | We perfectly assembled the monolayer V2C Mxene on the PET substrate. Size and craftsmanship can be customized. Uses: Energy storage, catalysis, analytical chemistry, mechanics, adsorption, biology, microelectronics, sensors, etc. Group: MXene Film and Heterojunction. CAS No. 12363-89-2. Flash Point: 0.99. | |
PET Substrate V2C MXene Quick inquiry Where to buy Suppliers range | We perfectly assembled the monolayer V2C Mxene on the PET substrate. Size and craftsmanship can be customized. Uses: Energy storage, catalysis, analytical chemistry, mechanics, adsorption, biology, microelectronics, sensors, etc. Group: MXene Film and Heterojunction. CAS No. 12012-17-8. Flash Point: 0.99. | |
PET Tablet Bottles Quick inquiry Where to buy Suppliers range | PET Tablet Bottles. Uses: Used for research and manufacturing. Group: Packaging Materials. Product ID: PM-042. | |
PET Therapy Bottles-Clear, Amber White or Black Quick inquiry Where to buy Suppliers range | PET Therapy Bottles-Clear, Amber White or Black. Uses: Used for research and manufacturing. Group: Packaging Materials. Product ID: PM-049. | |
Petunidin 3-D-Glucoside Quick inquiry Where to buy Suppliers range | Petunidin 3-D-Glucoside, a glycoside form of the O-methylated anthocyanidin, Petundin, shows anti-oxidant activities as well as having potential cytoprotective effects. Synonyms: Petunidin 3-O-β-D-Glucoside; 2-(3,4-dihydroxy-5-methoxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-1-benzopyrylium Chloride; 3-(Glucosyloxy)-3',4',5,7-tetrahydroxy-5'-methoxyflavylium Chloride; 3-(β-D-Glucopyranosyloxy)-3',4',5,7-tetrahydroxy-5'-methoxyflavylium Chloride; Petunidin 3-O-β-D-Glucopyranoside; Petunidin 3-Monoglucoside; Petunidin 3-β-D-Monoglucoside. Grades: > 95%. CAS No. 6988-81-4. Molecular formula: C22H23O12Cl. Mole weight: 514.86. | |
Peucedanol Quick inquiry Where to buy Suppliers range | Peucedanol. Group: Biochemicals. Alternative Names: Ohter Cas No, 20126-72-1. Grades: Plant Grade. CAS No. 20516-23-8. Pack Sizes: 10mg. Molecular Formula: C14H16O5, Molecular Weight: 264.274. US Biological Life Sciences. | Worldwide |
Pevonedistat Quick inquiry Where to buy Suppliers range | Pevonedistat Inhibitor. Uses: Scientific use. Product Category: T6332. CAS No. 905579-51-3. | |
Pevonedistat Quick inquiry Where to buy Suppliers range | Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. Uses: Enzyme inhibitors. Synonyms: TAK-924; TAK 924; TAK924; MLN4924; MLN 4924; BAY-73-4506; BAY 73-4506; BAY73-4506. Grades: ≥98% (HPLC). CAS No. 905579-51-3. Molecular formula: C21H25N5O4S. Mole weight: 443.52. | |
PE wax Quick inquiry Where to buy Suppliers range | PE wax. Group: Polymers. | |
Pexacerfont Quick inquiry Where to buy Suppliers range | Corticotropin-releasing factor (CRF), also known as corticotropin-releasing hormone, is an endogenous peptide hormone which is released in response to various triggers such as chronic stress. Pexacerfont is a potent and orally active CRF-1 antagonist trials for the treatment of anxiety disorders, and has also been proposed to be useful for the treatment of depression and irritable bowel syndrome. Uses: Crf-1 antagonist. Synonyms: BMS-562086; BMS 562086; BMS562086; BMS-562,086; BMS562,086; BMS 562,086; Pexacerfont.8-(6-Methoxy-2-methylpyridin-3-yl)-2,7-dimethyl-N-((1R)-1-methylpropyl)pyrazolo(1,5-a)-1,3,5-triazin-4-amine. Grades: ≥98%. CAS No. 459856-18-9. Molecular formula: C18H24N6O. Mole weight: 340.43. | |
Pexidartinib Quick inquiry Where to buy Suppliers range | Pexidartinib Inhibitor. Uses: Scientific use. Product Category: T2115. CAS No. 1029044-16-3. | |
Pexidartinib (PLX3397) Quick inquiry Where to buy Suppliers range | Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R with IC50 of 20 nM, Kit with IC50 of 10 nM, and Flt3 with IC50 160 nM. Phase 3, respectively. Synonyms: PLX3397; PLX-3397; PLX 3397; Pexidartinib. Grades: 98%. CAS No. 1029044-16-3. Molecular formula: C20H15ClF3N5. Mole weight: 417.81. | |
Pexiganan Quick inquiry Where to buy Suppliers range | Pexiganan is composed of 22 amino acids. In clinical manifestations, it has the advantages of low possibility of inducing drug resistance and no cross-resistance of existing therapeutic antibiotics. Pexiganan is a kind of cationic peptide with a strong antibacterial effect, with the characteristics of small molecular weight, rapid synthesis, rapid diffusion, strong alkalinity, high thermal stability, good water solubility, and unique antibacterial mechanism. Pexiganan has the broad-spectrum antibacterial ability, and it can kill viruses and tumor cells. More importantly, Pexiganan has no obvious toxic effect on normal cells of higher animals. Uses: Peptide Inhibitors. CAS No. 147664-63-9. Product ID: R1838. | |
Pexiganan Quick inquiry Where to buy Suppliers range | An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Grades: >95%. CAS No. 147664-63-9. Molecular formula: C122H209N31O23. Mole weight: 2478.19. | |
Pexiganan acetate Quick inquiry Where to buy Suppliers range | Pexiganan acetate is a short chain synthetic cationic peptides. It is being studied as potential antimicrobial agents. These peptides are found widely in nature in mammals, fish, insecs and amphibians. Uses: API. CAS No. 172820-23-4. Product ID: 10-101-182. | |
Pexiganan acetate Quick inquiry Where to buy Suppliers range | An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Synonyms: MSI 78; Pexiganan. Grades: >98%. CAS No. 172820-23-4. Molecular formula: C122H210N32O22.C2H4O2. Mole weight: 2537.22. | |
Pexmetinib Quick inquiry Where to buy Suppliers range | Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. It has potential antineoplastic, anti-inflammatory, and antiangiogenic activities. It inhibits other kinases including vascular endothelial growth factor receptor (VEGFR2) and Src tyrosine kinases. Synonyms: 1-(3-(tert-Butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)urea; Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]-; N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]urea; ARRY 614; ARRY-614; ARRY614; N-(3-tert-Butyl-1-p-tolyl-1H-pyrazol-5-yl)-N'-[5-fluoro-2-[1-(2-hydroxyethyl)-1H-indazol-5-yloxy]benzyl]urea. Grades: 98%. CAS No. 945614-12-0. Molecular formula: C31H33FN6O3. Mole weight: 556.63. | |
PF-00337210 Quick inquiry Where to buy Suppliers range | PF-00337210 is an orally available ATP-competitive inhibitor of the vascular endothelial growth factor receptor type 2 (VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, the VEGFR2 tyrosine kinase inhibitor PF-00337210 selectively binds to VEGFR2 and prevents its phosphorylation which may result in an inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and may eventually cause tumor cell death. VEGFR2, a receptor tyrosine kinase, is frequently overexpressed by a variety of tumor types. Synonyms: PF00337210; PF 00337210; PF-00337210; P337210; PF-337210; PF337210. CAS No. 854514-88-8. Molecular formula: C26H27N3O5. Mole weight: 461.51. | |
PF 00356231 Quick inquiry Where to buy Suppliers range | PF 00356231 is a MMP-12 inhibitor, and at high concentrations it also inhibits other MMPs. Synonyms: PF 00356231; PF00356231; PF-00356231; (3R)-3-phenyl-3-[[4-(4-pyridin-4-ylphenyl)thiophene-2-carbonyl]amino]propanoic acid. Grades: 98%. CAS No. 766536-21-4. Molecular formula: C25H20N2O3S. Mole weight: 428.5. | |
PF-00562271 Quick inquiry Where to buy Suppliers range | 939791-38-5, PF-562271 besylate, PF-00562271, PF-562271 (besylate), 939791-38-5 (besylate), PF-562271 (benzesulfonate salt), N-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate, FK2M84H8UI, PF 562271, CHEMBL2430359, PF-562271 PHSO3H SALT, N-[3-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide benzenesulfonate, N-methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide benzenesulfonate, PF-562271 BESILATE, benzenesulfonic acid;N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide, PF 562271 besylate, D01SJT, UNII-FK2M84H8UI, PF-00562271 Besylate, PF-562271 benzenesulfonate, SCHEMBL20471937, DTXSID40240064, EX-A573, HMS3651N09, BCP14770, MFCD14105612, s2672, PF 562271 [WHO-DD], AKOS025401942, CCG-270344, SB12448, AC-27465, AS-75267, HY-10458, FT-0700417, SW219484-1, A12580, PF 00562271-26, PF-562,271, >=98% (HPLC), J-523694, Methanesulfonamide, N-(3-(((2-((2,3-dihydro-2-oxo-1H-indol-5-yl)amino)-5- (trifluoromethyl)-4-pyrimidinyl)amino)methyl)-2-pyridinyl)-N-methyl-, benzenesulfonate (1:1), METHANESULFONAMIDE, N-(3-(((2-((2,3-DIHYDRO-2-OXO-1H-INDOL-5-YL)AMINO)-5-(TRIFLUOROMETHYL)-4-PYRIMIDINYL)AMINO)METHYL)-2-PYRIDINYL)-N-METHYL-, BENZENESULFONATE, N-Methyl-n-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide benzene sulfonate, N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide; benzenesulfonic acid. | |
Pf-01247324 Quick inquiry Where to buy Suppliers range | PF-01247324 is a subtype-selective Nav1.8 blocker, for study cerebellar dysfunction in MS and related disorders. Uses: Pf-01247324 is a selective nav 1.8 channel blocker. Synonyms: 6-amino-N-methyl-5-(2,3,5-trichlorophenyl)picolinamide; PF 01247324. Grades: 98%. CAS No. 875051-72-2. Molecular formula: C13H10Cl3N3O. Mole weight: 330.60. | |
PF-03049423 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 402955-58-2. Pack Sizes: 5MG, 25MG. Mole weight: 468.55 (free base basis). Catalog: AP402955582. Assay: ≥98% (HPLC). | |
PF-03084014 Quick inquiry Where to buy Suppliers range | Cas No. 865773-15-5. | |
PF-03084014 hydrobromide Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1290543-63-3 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 570.56. Catalog: ALP1290543633. Assay: ≥98% (HPLC). | |
PF-03246799 hydrochloride Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1065114-52-4. Pack Sizes: 5MG, 25MG. Mole weight: 239.32 (free base basis). Catalog: AP1065114524. Assay: ≥98% (HPLC). | |
PF-03654746 Tosylate Quick inquiry Where to buy Suppliers range | PF-03654746 Tosylate is a histamine H3 receptor antagonist undergoing a clinical trial for attention-deficit hyperactivity disorder (ADHD) therapy. Uses: Potential treatment of adhd. Synonyms: Trans-N-Ethyl-3-fluoro-3-[3-fluoro-4-(1-pyrrolidinylmethyl)phenyl]-cyclobutanecarboxamide 4-methylbenzenesulfonate; PF-03654746, 4-Methylbenzenesulfonate. Grades: 99%. CAS No. 1039399-17-1. Molecular formula: C18H24F2N2O.C7H8O3S. Mole weight: 494.59. | |
PF-03671148 Quick inquiry Where to buy Suppliers range | PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring. Synonyms: PF03671148; PF 03671148. CAS No. 1378524-25-4. Molecular formula: C18H15N5O. Mole weight: 317.35. | |
PF-03758309 Quick inquiry Where to buy Suppliers range | PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also an orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival. Synonyms: PF03758309; PF 03758309; PF-3758309; PF3758309; PF 3758309. Grades: >98%. CAS No. 898044-15-0. Molecular formula: C25H30N8OS. Mole weight: 490.63. | |
PF 03814735 Quick inquiry Where to buy Suppliers range | PF 03814735. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 942487-16-3. Molecular formula: C23H25F3N6O2. Mole weight: 474.48. Catalog: APS942487163. SMILES: CC (=O)NCC (=O)N1[C@H]2CC[C@@H]1c3cc (Nc4ncc (c (NC5CCC5)n4)C (F) (F)F)ccc23. Format: Neat. | |
PF 03814735 Quick inquiry Where to buy Suppliers range | PF 03814735 is an orally bioavailable small molecule aurora kinase inhibitor that plays a key role in the regulation of mitosis. PF 03814735 is a anticancer agent used for cancer therapy. Group: Biochemicals. Alternative Names: N-[2-[(1S,4R)-6-[[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]-acetamide. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
PF-03814735 Quick inquiry Where to buy Suppliers range | PF-03814735 is an orally bioavailable, ATP-competitive, reversible small-molecule Aurora kinase inhibitor with potential antineoplastic activity. Aurora kinase inhibitor PF-03814735 binds to and inhibits Aurora kinases A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Aurora kinases are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Synonyms: PF03814735; PF-03814735; PF 03814735. Grades: >98%. CAS No. 942487-16-3. Molecular formula: C23H25F3N6O2. Mole weight: 474.48. | |
PF 03814735 (Aurora Kinases A and B, N-[2-[(1S,4R)-6-[[4-(Cyclobutylamin o)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3, 4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]- acetamide) Quick inquiry Where to buy Suppliers range | ATP-competitive inhibitor of Aurora kinases A and B (IC50 values are 0.8 and 5nm for recombinant Aurora B and Aurora A, respectively). Inhibits phosphorylation of Aurora B, histone H3 and Aurora A in cultured MDA-MB-231 cells (IC50 values are ~20, 50 and 150nm respectively). Shown to block cytokinesis; inhibits cellular proliferation in several human tumor cell lines, including HCT-116, HL-60, A549 and H125, and in human xenograft mouse models. Orally available. Group: Biochemicals. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
PF-04171327 Quick inquiry Where to buy Suppliers range | PF-04171327 is a dissociated agonist of the glucocorticoid receptor (DAGR), which is a selective high-affinity partial agonist of the GR. It has potent anti-inflammatory activity at exposures which provide less undesirable effects on bone and glucose metabolism. It is used to the treatment of rheumatoid arthritis. It was developed by Pfizer and was terminated in clinic phase 2. Uses: Pf-04171327 has potent anti-inflammatory activity. it is used to the treatment of rheumatoid arthritis. Synonyms: PF-04171327; PF04171327; PF 04171327; PF-4171327; PF4171327; PF 4171327; Fosdagrocorat;(2R,4aS,10aR)-4a-benzyl-7-((2-methylpyridin-3-yl)carbamoyl)-2-(trifluoromethyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthren-2-yl dihydrogen phosphate. Grades: >98 %. CAS No. 1044535-58-1. Molecular formula: C29H30F3N2O5P. Mole weight: 574.53. | |
PF04191834 Quick inquiry Where to buy Suppliers range | PF04191834 is a novel, potent and selective non-redox 5-lipoxygenase(5-LOX) inhibitor with an IC50 value of 229 +/- 20 nM. It inhibits 5-LOX in human blood cells with an IC80 value of 370 +/- 20 nM. It exhibits good potency in enzyme- and cell-based assays, as well as in a rat model of acute inflammation. It demonstrated approximately 300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and shows no activity toward the cyclooxygenase enzymes. It is effective in inflammation and pain. Uses: Pf04191834 is effective in inflammation and pain. Synonyms: PF-04191834; PF04191834; PF 04191834; PF-4191834; PF4191834; PF 4191834. 4-(3-((4-(1-Methyl-1H-pyrazol-5-yl)phenyl)thio)phenyl)tetrahydro-2H-pyran-4-carboxamide. Grades: >98 %. CAS No. 1029317-21-2. Molecular formula: C22H23N3O2S. Mole weight: 393.51. | |
PF-04217329 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1005549-94-9. Pack Sizes: 5MG, 25MG. Mole weight: 520.60. Catalog: AP1005549949. Assay: ≥98% (HPLC). | |
PF-04217903 Quick inquiry Where to buy Suppliers range | PF-04136309 is an orally available human chemokine receptor 2 (CCR2) antagonist with potential immunomodulating and antineoplastic activities. Upon oral administration, CCR2 antagonist PF-04136309 specifically binds to CCR2 and prevents binding of the endothelium-derived chemokine ligand CLL2 (monocyte chemoattractant protein-1 or MCP1) to its receptor CCR2, which may result in inhibition of CCR2 activation and signal transduction. This may inhibit inflammatory processes as well as angiogenesis, tumor cell migration, and tumor cell proliferation. The G-protein coupled receptor CCR2 is expressed on the surface of monocytes and macrophages, stimulates the migration and infiltration of these cell types, and plays an important role in inflammation, angiogenesis, and tumor cell migration and proliferation. Synonyms: PF-04217903; PF 04217903; PF04217903; PF-4217903; PF4217903; PF 4217903. Grades: >98%. CAS No. 956905-27-4. Molecular formula: C19H16N8O. Mole weight: 372.392. | |
PF-04217903 methanesulfonate Quick inquiry Where to buy Suppliers range | PF-04217903 methanesulfonate is a selective ATP-competitive c-Met inhibitor and is susceptible to oncogenic mutations (no activity to Y1230C mutant). It showed more than 1000-fold greater selectivity against c-Met kinase over 150 other kinases. It displays similar potency to inhibit the activity of c-Met-H1094R, c-Met-R988C, and c-Met-T1010I, but has no inhibitory activity against c-Met-Y1230C. It showed antitumor activity in tumor models where c-Met is activated by mechanisms including c-Met gene amplification, HGF/c-Met autocrine loop formation or c-Met overexpression. It suppressed proliferation of c-Met-amplified GTL-16 and H1993cells. It induced apoptosis in GTL-16 cells. It inhibited the phosphorylation of c-Met and suppressed tumor growth. Synonyms: PF-04217903 methanesulfonate; PF 04217903 methanesulfonate; PF04217903 methanesulfonate. Grades: >98%. CAS No. 956906-93-7. Molecular formula: C20H20N8O4S. Mole weight: 468.49. | |
PF-04363467 hydrochloride Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 2040055-81-8 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 439.01. Catalog: ALP2040055818. Assay: ≥98% (HPLC). | |
PF 04418948 Quick inquiry Where to buy Suppliers range | PF 04418948 acts as a novel, potent and selective prostoglandin EP2 receptor antagonist. Group: Biochemicals. Alternative Names: (1-(-fluorbenzoyl)-3-{[(6-methoxy-2-napthyl)oxy]methyl} Azetidine-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
PF-04418948 Quick inquiry Where to buy Suppliers range | PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. Synonyms: PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948. Grades: 98%. CAS No. 1078166-57-0. Molecular formula: C23H20FNO5. Mole weight: 409.41. | |
PF-04447943 Quick inquiry Where to buy Suppliers range | PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and 18 nM) for human, rhesus and rat recombinant PDE9 respectively and high selectivity for PDE9 versus PDEs1-8 and 10-11. Synonyms: PF-04447943; PF 04447943; PF04447943; PF-4447943; PF 4447943; PF4447943. Grades: >98%. CAS No. 1082744-20-4. Molecular formula: C20H25N7O2. Mole weight: 395.46. | |
PF-04447943 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1082744-20-4. Pack Sizes: 5MG, 25MG. Mole weight: 395.46. Catalog: AP1082744204. Assay: ≥98% (HPLC). | |
PF 04449613 Quick inquiry Where to buy Suppliers range | PF 04449613 is a potent PDE9 inhibitor (IC50 = 22 nM), and also shows a high affinity for cGMP (Km ~170 nM). Some studies suggest that elevating the level of cGMP with the PDE9 inhibitor PF-04449613 increases synaptic calcium activity and learning-dependent synaptic plasticity. Synonyms: (R)-6-(1-(3-Phenoxyazetidin-1-yl)ethyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one; 1,5-Dihydro-6-[(1R)-1-(3-phenoxy-1-azetidinyl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)-4H-pyrazolo[3,4-d]pyrimidin-4-one, 6-[(1R)-1-(3-Phenoxyazetidin-1-yl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; PF 4449613; PF 9613; PF4449613; PF9613; PF-4449613; PF-9613. Grades: ≥98% by HPLC. CAS No. 1236858-52-8. Molecular formula: C21H25N5O3. Mole weight: 395.45. | |
PF-04449913 maleate salt Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1095173-27-5 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 490.51. Catalog: ALP1095173275. Assay: ≥98% (HPLC). | |
PF-04457845 Quick inquiry Where to buy Suppliers range | PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen. Synonyms: PF-04457845; PF 04457845; PF04457845; PF-4457845; PF 4457845; PF4457845. Grades: >98%. CAS No. 1020315-31-4. Molecular formula: C23H20F3N5O2. Mole weight: 455.43. | |
PF-04479745 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1065110-43-1. Pack Sizes: 5MG, 25MG. Mole weight: 282.38. Catalog: AP1065110431. Assay: ≥98% (HPLC). | |
PF-04531083 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1079400-07-9. Pack Sizes: 5MG, 25MG. Mole weight: 357.79. Catalog: AP1079400079. Assay: ≥98% (HPLC). | |
PF-04620110 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1109276-89-2. Pack Sizes: 5MG, 25MG. Mole weight: 396.44. Catalog: AP1109276892. Assay: ≥98% (HPLC). | |
PF-04620110 Quick inquiry Where to buy Suppliers range | PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM. Synonyms: PF-04620110; PF 04620110; PF04620110. PF-4620110; PF 4620110; PF4620110. Grades: >98%. CAS No. 1109276-89-2. Molecular formula: C21H24N4O4. Mole weight: 396.44. | |
PF 04628935 Quick inquiry Where to buy Suppliers range | PF 04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth hormone secretagogue receptor 1a (GHS-R1a) with an IC50 of 4.6 nM. It is orally bioavailable and exhibits reasonable brain penetration. Synonyms: 1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone; PF-04628935; PF04628935; PF 04628935; PF-4628935; PF4628935; PF 4628935. Grades: ≥98% by HPLC. CAS No. 1383719-97-8. Molecular formula: C24H26ClN7OS. Mole weight: 496.03. | |
PF-04634817 Quick inquiry Where to buy Suppliers range | PF-04634817 is a dual CCR2/CCR5 antagonist, which can be used to treat diabetic nephropathy and diabetic macular edema. Synonyms: PF-04634817; 1228111-63-4; UNII-51M3FB9B9E51M3FB9B9E[(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[(1S,4S)-5-[6-(trifluoromethyl)pyrimidin-4-yl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]methanone. CAS No. 1228111-63-4. Molecular formula: C25H36F3N5O3. Mole weight: 511.6. | |
PF-04634817 succinate Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1228111-63-4 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 629.67. Catalog: ALP1228111634. Assay: ≥98% (HPLC). | |
PF 04671536 hydrochloride Quick inquiry Where to buy Suppliers range | PF 04671536 is a highly potent and selective inhibitor of phosphodiesterase 8B (PDE8B) phosphodiesterase 8A (PDE8A) (IC50= 1.3 and 1.9 nM, respectively), with selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Synonyms: PF-04671536 hydrochloride; PF04671536 hydrochloride; PF 04671536 hydrochloride; PF-04671536 HCL; PF04671536 HCL; PF 04671536 HCL; PF04671536HCL; 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 1305116-67-9. Molecular formula: C14H18N8OS.HCl. Mole weight: 382.87. | |
PF-04691502 Quick inquiry Where to buy Suppliers range | PF-04691502 is an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. It inhibits both PI3K and mTOR kinases, which may result in apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy. mTOR, a serine/threonine kinase downstream of PI3K, may also be activated independent of PI3K. Synonyms: PF04691502; PF 04691502; PF-04691502; PF4691502; PF 4691502; PF-4691502; 2-amino-8-((1R,4R)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Grades: > 98%. CAS No. 1013101-36-4. Molecular formula: C22H27N5O4. Mole weight: 425.489. | |
PF 04691502 (2-Amino-8-[trans-4-(2-hydroxyethoxy )cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-py rido[2,3-d]pyrimidin-7(8H)-one) Quick inquiry Where to buy Suppliers range | Potent and selective dual ATP-competitive PI 3-K/mTOR inhibitor (Ki values are 1.6, 1.8, 1.9, 2.1 and 16nm for human PI 3-K delta, alpha, gamma, beta, and mTOR, respectively). Displays no significant inhibitory activity at more than 80 protein kinases (concentration ≥ 10um) including hVps34, PI 3-K downstream kinases, and MAPK family members. Orally available. Induces robust cell cycle arrest at the G1 phase in U87MG cancer cells and antitumor activity in SKOV3 ovarian cancer xenograft models. Group: Biochemicals. Grades: Highly Purified. CAS No. 1013101-36-4. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
PF-04856264 Quick inquiry Where to buy Suppliers range | This active molecular is a human Nav1.7 voltage gated sodium channel inhibitor with the IC50 value of 28 nM. PF-04856264 inhibits the Nav channel by interacting with the S1-S4 voltage sensor segment of homologous domain 4 which is unlike other known NaV inhibitors. PF-04856264 interaction with the region of the channel which controls voltage sensitivity enables subtype selective modulation and may be applicated as an efficient tool for drug development. Synonyms: PF-04856264; PF04856264; PF 04856264; PF-4856264; PF4856264; PF 4856264. 3-cyano-4-(2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-N-(thiazol-2-yl)benzenesulfonamide. Grades: 98%. CAS No. 1235397-05-3. Molecular formula: C20H15N5O3S2. Mole weight: 437.49. |