A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Reveromycin A. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2E,6E,8E)-10-[3-butyl-2-[(1E,3E)-4-carboxy-3-methylbuta-1,3-dienyl]-3-(3-carboxypropanoyloxy)-9-methyl-1,7-dioxaspiro[5.5]undecan-8-yl]-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid. Appearance: Lyophilized. CAS No. 134615-37-5. Molecular formula: C36H52O11. Mole weight: 660.8. Purity: 0.99. Canonical SMILES: CCCCC1(CCC2(CCC(C(O2)CC=C(C)C=CC(C(C)C=CC(=O)O)O)C)OC1C=CC(=CC(=O)O)C)OC(=O)CCC(=O)O. Product ID: ACM134615375. Alfa Chemistry ISO 9001:2015 Certified.
Reveromycin A
The dominant analogue of complex of spiroketals isolated from streptomyces sp. It is an inhibitor of the mitogenic activity of EGF and a G1 phase cell cycle inhibitor. It selectively inhibits isoleucyl-trna synthetase. It has anti-proliferation effect on human cell lines KB and K562, and has potent antifungal activity. Synonyms: (-)-Reveromycin A; [2S-[2α(1E, 3E), 3β, 6α[8S*(2E, 4E, 6R*, 7R*, 8E), 9R*]]]-butanedioic acid mono[3-butyl-8-(9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl)-2-(4-carboxy-3-methyl-1,3-butadienyl)-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester; Butanedioic Acid Mono[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester. Grades: >99% by HPLC. CAS No. 134615-37-5. Molecular formula: C36H52O11. Mole weight: 660.79.
Reveromycin A
Reveromycin A, a benzoquinoid antibiotic isolated from the genus Streptomyces , is a selective inhibitor of protein synthesis in eukaryotic cells. Reveromycin A inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Reveromycin A has antiproliferative activity against tumor cell lines and antifungal activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 134615-37-5. Pack Sizes: 1 mg. Product ID: HY-129337.
Reveromycin A
Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of epidermal growth factor (EGF). It is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behavior against human cell lines KB and K562 as well as potent antifungal activity. More recently it has been shown to inducing apoptosis in osteoclasts thus inhibiting bone resorption. Group: Biochemicals. Grades: Highly Purified. CAS No. 134615-37-5. Pack Sizes: 250ug. US Biological Life Sciences.
Reveromycin B is a polyketide antibiotic isolated from Streptomyces, which can inhibit mitotic activity. Synonyms: BDBM50217842; ZINC49871994. Grades: >98% by HPLC. CAS No. 144860-68-4. Molecular formula: C36H52O11. Mole weight: 660.79.
Reveromycin B
Reveromycin B is an much less active analogue of reveromycin A formed by rearrangement of the 6to6 spiroketal to a 5to6 spiroketal. Lacking much of the biological activity of reveromycin A, the reveromycin B is a useful negative control in resolving the mode of action of this class. Group: Biochemicals. Grades: Highly Purified. CAS No. 144860-68-4. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Reveromycin C
Reveromycin C is a minor analogue of the reveromycin complex isolated from a Streptomyces sp. Published information suggests that reveromycin C exhibits comparable potency to reveromycin A, its butyl homologue. In Microbial Screening Technologies in-house screens Reveromycins C and A had similar biological profiles but Reveromycin C was generally more potent. Group: Biochemicals. Grades: Highly Purified. CAS No. 144860-69-5. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Reveromycin C
Reveromycin C. Uses: Designed for use in research and industrial production. Additional or Alternative Names: REVEROMYCIN C. Product Category: Heterocyclic Organic Compound. Appearance: White to tan solid. CAS No. 144860-69-5. Molecular formula: C37H54O11. Mole weight: 674.8. Purity: 0.95. Canonical SMILES: CC(C)CCC1(CCC2(CCC(C)C(C/C=C(\\C)/C=C/C(O)C(C)/C=C/C(=O)O)O2)OC1/C=C/C(=C/C( =O)O)/C)OC(=O)CCC(=O)O. Product ID: ACM144860695. Alfa Chemistry ISO 9001:2015 Certified.
Reveromycin C
Reveromycin C is a polyketide isolated from Streptomyces. It is an antibiotic inhibitor with mitotic activity that responds to EGF. Grades: >95% by HPLC. CAS No. 144860-69-5. Molecular formula: C37H54O11. Mole weight: 674.82.
Reveromycin D
Reveromycin D is a bacterial metabolite isolated from Streptomyces. It inhibits EGF-induced mitotic activity in Balb/MK cells and has pH-dependent antifungal activity against Candida albicans. Grades: >95% by HPLC. CAS No. 144860-70-8. Molecular formula: C37H54O11. Mole weight: 674.82.
Reveromycin D
Reveromycin D, the isopentyl analogue, is a minor component of the reveromycin complex isolated from a Streptomyces sp. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C. Group: Biochemicals. Grades: Highly Purified. CAS No. 144860-70-8. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Reversan
Reversan is a selective inhibitor of multidrug resistance-associated protein 1 (Mdr-1) and P-glycoprotein (P-gp), which may be clinically useful for the treatment of neuroblastoma. Synonyms: N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide. Grades: ≥99% by HPLC. CAS No. 313397-13-6. Molecular formula: C26H27N5O2. Mole weight: 441.52.
Reversan
Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CBLC4H10. CAS No. 313397-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107643.
Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma. Group: Biochemicals. Alternative Names: N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide. Grades: Highly Purified. CAS No. 313397-13-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Reverse T3
Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine [1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,5,3-Triiodothyronine. CAS No. 5817-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-W010696.
Reverse Transcriptase from HIV, Recombinant
Chromatographically purified heterodimer composed of 66kDa and 51kDa subunits. Supplied as a solution in 10mM potassium phosphate, pH 7.4, 1mM DTT and 20% glycerol. Primarily for AIDS research purposes; this enzyme has less fidelity than the AMV enzyme in other applications such as the preparation of cDNA from mRNA for cloning purposes. Applications: Hiv reverse transcriptase is used for research on the aids primer. however it can be substituted for amv reverse transcriptase, which is mainly used to transcribe mrna into double stranded cdna, that can be inserted into prokaryotic vectors. the enzyme can also be used with either single stranded dna or rna templates to mak...or labeling the termini of dna fragments with protruding 5' termini. the enzyme can also be used to sequence dnas by the dideoxy chain termination method of sanger when the klenow fragment of e. coli dna polymerase i, or the t7 dna polymerase yield unsatisfactory results. Group: Enzymes. Synonyms: Reverse transcriptase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. Purity: Chromatographically purified. RT. Mole weight: 66 kDa and 51 kDa. Activity: > 5,000 units per mg protein. Storage: Store at -20°C. Form: A solution in 10mM potassium phosphate, pH 7.4, 1mM DTT and 20% glycerol. Source: E. coli. Species: HIV. Reverse transcriptase; RT. Cat No: NATE-0987.
Reverse Transcriptase from Moloney Murine Leukemia Virus, Recombinant
This Reverse Transcriptase has exceptionally strong strand displacement activity and enables efficient preparation of cDNA up to 12 kb in length. It is robust, versatile and well-suited for applications requiring full-length cDNA such as preparation of cDNA libraries and other techniques involving first strand cDNA synthesis (RT-PCR, preparation of cDNA probes, real-time quantitative RT-PCR). It can be used for performing a reverse transcription reaction with any RNA template including GC-rich templates and RNAs with high levels of secondary structure. This enzyme is a modified, recombinant MMLV (Moloney Murine Leukemia Virus) reverse transcriptase and is v...ptases tested; 4. highly specific: low rates of non-specific annealing, even on incompletely denatured rna; 5. works on challenging templates: excellent results even with gc-rich templates and templates with high levels of secondary structure 6. highly sensitive: use less of your precious rna samples; 7. demonstrated success with reverse transcription reaction times of 30 min. (60 min. for longer transcripts). Applications: Rt-pcr; first strand cdna synthesis; cdna probe preparation; synthesis of cdna libraries with a high proportion of full-length cdnas. Group: Enzymes. Synonyms: Reverse transcriptase; RT. RT. Storage: Storage at-20°C. Source: E. coli. Spec
Reverse transcriptase-IN-1
Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC 50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 III B , E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC 50 of 13.7 nM against HIV-1 reverse transcriptase enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380001-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130241.
Reversin 121
Reversin 121 is a selective P-glycoprotein multidrug transporter (MDR1) inhibitor with Kd value of 77 nM. Synonyms: reversin 121; 174630-04-7; CHEMBL221390; tert-butyl (2S) -2-[[ (2S) -2-[ (2-methylpropan-2-yl) oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoyl]amino]-6- (phenylmethoxycarbonylamino) hexanoate; Boc-Asp(Obzl)-Lys(Z)-OtBu; BDBM50326927; DB14072; HY-125486; Reversin 121, >=97% (HPLC), powder; CS-0091919; (S)-tert-butyl 2-((S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)-4-oxobutanamido)-6-(benzyloxycarbonylamino)hexanoate; tert-Butyl N2-((S)-4-(benzyloxy)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoyl)-N6-((benzyloxy)carbonyl)-L-lysinate. Grades: ≥98%. CAS No. 174630-04-7. Molecular formula: C34H47N3O9. Mole weight: 641.8.
?98% (HPLC), film. Group: Fluorescence/luminescence spectroscopy.
Reversine
Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC 50 s of 400, 500 and 400 nM for Aurora A , Aurora B and Aurora C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 656820-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14711.
Reversine
Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Synonyms: Reversine; 656820-32-5; 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine; CHEMBL188343; CHEBI:70723; C21H27N7O; N6-cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2,6-diamine; N6-cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine; Z499CLJ023; MFCD07784513; N~6~-Cyclohexyl-N~2~-(4-Morpholin-4-Ylphenyl)-9h-Purine-2,6-Diamine; N(6)-cyclohexyl-N(2)-[4-(morpholin-4-yl)phenyl]-9H-purine-2,6-diamine; 2vgo. CAS No. 656820-32-5. Molecular formula: C21H27N7O. Mole weight: 393.49.
A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66uM) and an aurora kinase inhibitor (IC??'s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 656820-32-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Revexepride
Revexepride, also referred as SSP-002358, is a very selective and potent 5-HT4 receptor agonist and a novel prokinetic that stimulates gastrointestinal motility, and could be a good candidate drug for the gastroparesis treatment. Synonyms: 4-amino-5-chloro-N-[[(3S,4S)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl]methyl]-2,2-dimethyl-3H-1-benzofuran-7-carboxamide; revexepride; SSP-002358; SSP 002358; SSP002358; Revexepride. Grades: >98%. CAS No. 219984-49-3. Molecular formula: C21H32ClN3O4. Mole weight: 425.95.
Revised PVOC Mixture
certified reference material, 2000 ?g/mL each component in methanol. Group: Certified reference materials (crms).
Revumenib
Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding K i of 0.149 nM and a cell based IC 50 of 10-20 nM. Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNDX-5613. CAS No. 2169919-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136175.
Rexamino
Rexamino. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,5-Dihydro-4-phenyl-. Product Category: Heterocyclic Organic Compound. CAS No. 52883-35-9. Molecular formula: C9H10N2O. Mole weight: 162.19. Purity: 0.96. IUPACName: 4-phenyl-4,5-dihydro-1,3-oxazol-2-amine. Canonical SMILES: C1C(N=C(O1)N)C2=CC=CC=C2. Density: 1.264g/cm³. Product ID: ACM52883359. Alfa Chemistry ISO 9001:2015 Certified.
Rezafungin
Rezafungin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396640-59-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396640597.
Rezafungin acetate
Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp. , Aspergillus spp. , and Pneumocystis spp. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Biafungin acetate; CD101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108009A.
Rezafungin Impurity 1
Rezafungin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396639-48-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396639487.
Rezafungin Impurity 2
Rezafungin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396640-55-3. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396640553.
Rezafungin Impurity 9
Rezafungin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1672717-33-7. Molecular formula: C63H86N9O17+. Mole weight: 1241.43. Catalog: APB1672717337.
Rezatapopt
Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PC14586. CAS No. 2636846-41-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156633.
Rezatomidine
Rezatomidine is a selective α2-adrenoreceptor antagonist under the development of Allergan. No recent development was reported for the treatment of Diabetic neuropathies and Fibromyalgia. Synonyms: 2H-Imidazole-2-thione, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1,3-dihydro-; (S)-4-(1-(2,3-dimethylphenyl)ethyl)-1,3-dihydro-2H-imidazole-2-thione; 4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1,3-dihydro-2H-imidazole-2-thione; (+)-(S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1,3-dihydroimidazole-2-thione. Grades: 98%. CAS No. 847829-38-3. Molecular formula: C13H16N2S. Mole weight: 232.35.
Rezorstobart
Rezorstobart is an anti- KLRB1 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2762201-86-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990760.
Rezvilutamide
Rezvilutamide (SHR3680) is an orally active androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR3680. CAS No. 1572045-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137448.
RF9
RF9 is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 876310-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107382.
RF 9
RF 9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively. It displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Synonyms: 2-Adamantanecarbonyl-Arg-Phe-NH2. Grades: ≥96%. CAS No. 876310-60-0. Molecular formula: C26H38N6O3. Mole weight: 482.62.
RF9 (1-Adamantanecarbonyl-Arg-Phe-NH2)
Selective NPFF receptor antagonist (Ki values are 58 and 75nM at hNPFF1 and hNPFF2 receptors respectively). Displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo. Group: Biochemicals. Alternative Names: 1-Adamantanecarbonyl-Arg-Phe-NH2. Grades: Highly Purified. CAS No. 876310-60-0. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 482.62 free base. US Biological Life Sciences.
A metabolite of of terfenadine, a H1-Histamine receptor antagonist. Group: Biochemicals. Alternative Names: R-Carboxyterfenadine, R-Terfenadinecarboxyl ate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
r-(-)-Flecainide
r-(-)-Flecainide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(2R)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (R)-Flecainide; (-)-Flecainide. Product Category: Heterocyclic Organic Compound. CAS No. 99495-90-6. Molecular formula: C17H20F6N2O3. Mole weight: 414.34. Product ID: ACM99495906. Alfa Chemistry ISO 9001:2015 Certified.
R-(-)-Flecainide
A stereoisomer of Flecainide. Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia. Synonyms: N-[(2R)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (R)-Flecainide; (-)-Flecainide. Grades: > 95%. CAS No. 99495-90-6. Molecular formula: C17H20F6N2O3. Mole weight: 414.35.
R-(-)-Flecainide
R-(-)-Flecainide. Group: Biochemicals. Alternative Names: N-[ (2R) -2-Piperidinylmethyl]-2, 5-bis (2, 2, 2-trifluoroethoxy) benzamide; (R)-Flecainide; (-)-Flecainide. Grades: Highly Purified. CAS No. 99495-90-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H20F6N2O3. US Biological Life Sciences.
R-Flurbiprofen-acyl-β-D-glucuronide is a metabolite of (R)-Flurbiprofen, the stereoisomer of Flurbiprofen. Synonyms: (R)Flurbiprofen-acyl-b-D-glucuronide. Grades: > 95%. CAS No. 162992-67-8. Molecular formula: C21H21F1O8. Mole weight: 420.39.
RFP Expressing Glomerular Microvascular Endothelial Cells, Human (Frozen)
RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Glomerular Microvascular Endothelial Cells, Human (T-25 flask)
RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Retinal Microvascular Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Retinal Microvascular Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
RFRP-1 (human), a mammalian ortholog of avian gonadotropin inhibitory hormone (GnIH), is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). RFRP-1 exhibits anorexigenic, anti-fertility, and anxiogenic activities. RFRP-1-secreting neurons are stress activated and inhibit the secretion of gonadotropin and gonadotropin-releasing hormone (GnRH). In vivo, this peptide inhibits reproductive behavior, decreases food intake, and increases anxiety behavior in an oxytocin-mediated manner. Synonyms: MPHSFANLPLRF; MPHSFANLPLRF-NH2. CAS No. 311309-25-8. Molecular formula: C67H101N19O14S. Mole weight: 1428.72.
RFRP-1(human)
RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428.
RFRP 3 (human)
RFRP 3 (human). Group: Biochemicals. Grades: Purified. CAS No. 311309-27-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
RFRP 3 (human)
RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization. Synonyms: NPVF; Neuropeptide VF (124-131) (human); H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; Neuropeptide NPVF; RFamide-related peptide 3; L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2. Grades: ≥95% by HPLC. CAS No. 311309-27-0. Molecular formula: C45H72N14O10. Mole weight: 969.15.
RFRP-3(human)
RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC 50 of 0.7 nM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human). CAS No. 311309-27-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1250.
RFRP3 (human) acetate
RFRP3 (human) acetate, a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP3 can effectively inhibit GNRH-stimulated gonadotropin secretion in sheep in vivo and in culture by inhibiting Ca2+ mobilization. Synonyms: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid; RFRP-3 acetate; RFRP 3 acetate; RFamide-related peptide-3 acetate. Grades: ≥95%. Molecular formula: C47H76N14O12. Mole weight: 1029.19.
RG100204
RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H2O2. RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2140901-88-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161834.
RG 102240
RG 102240 is a stimulant, which induces a potent activator of gene expression. It does not cause significant changes in endogenous gene expression in HEK cells. Synonyms: 2-Ethyl-3-methoxybenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide; GS-E; GS-E (ligand); RSL 1; RheoSwitch Ligand 1; RheoSwitch Ligand RSL 1; RG-102240; RG 102240; RG102240. Grades: ≥98% by HPLC. CAS No. 162326-49-0. Molecular formula: C23H30N2O3. Mole weight: 382.5.
RG108
RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Phthalyl-L-tryptophan. CAS No. 48208-26-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13642.