American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
RFP Expressing Retinal Microvascular Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
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RFP Expressing Saphenous Vein Endothelial Cells, Human (Frozen) Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (Frozen) Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
Worldwide
R-Frovatriptan . Uses: Tryptamines; carbazoles. Synonyms: (3R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide. Grades: > 95%. CAS No. 158747-02-5. Molecular formula: C14H19N3O. Mole weight: 243.33. BOC Sciences 8
RFRP-1 (human) RFRP-1 (human), a mammalian ortholog of avian gonadotropin inhibitory hormone (GnIH), is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). RFRP-1 exhibits anorexigenic, anti-fertility, and anxiogenic activities. RFRP-1-secreting neurons are stress activated and inhibit the secretion of gonadotropin and gonadotropin-releasing hormone (GnRH). In vivo, this peptide inhibits reproductive behavior, decreases food intake, and increases anxiety behavior in an oxytocin-mediated manner. Synonyms: MPHSFANLPLRF; MPHSFANLPLRF-NH2. CAS No. 311309-25-8. Molecular formula: C67H101N19O14S. Mole weight: 1428.72. BOC Sciences 9
RFRP-1(human) RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428. MedChemExpress MCE
RFRP 3 (human) RFRP 3 (human). Group: Biochemicals. Grades: Purified. CAS No. 311309-27-0. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 5
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RFRP 3 (human) RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization. Synonyms: NPVF; Neuropeptide VF (124-131) (human); H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; Neuropeptide NPVF; RFamide-related peptide 3; L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2. Grades: ≥95% by HPLC. CAS No. 311309-27-0. Molecular formula: C45H72N14O10. Mole weight: 969.15. BOC Sciences 9
RFRP-3(human) RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC 50 of 0.7 nM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human). CAS No. 311309-27-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1250. MedChemExpress MCE
RFRP3 (human) acetate RFRP3 (human) acetate, a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP3 can effectively inhibit GNRH-stimulated gonadotropin secretion in sheep in vivo and in culture by inhibiting Ca2+ mobilization. Synonyms: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid; RFRP-3 acetate; RFRP 3 acetate; RFamide-related peptide-3 acetate. Grades: ≥95%. Molecular formula: C47H76N14O12. Mole weight: 1029.19. BOC Sciences 6
RG 102240 RG 102240 is a stimulant, which induces a potent activator of gene expression. It does not cause significant changes in endogenous gene expression in HEK cells. Synonyms: 2-Ethyl-3-methoxybenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide; GS-E; GS-E (ligand); RSL 1; RheoSwitch Ligand 1; RheoSwitch Ligand RSL 1; RG-102240; RG 102240; RG102240. Grades: ≥98% by HPLC. CAS No. 162326-49-0. Molecular formula: C23H30N2O3. Mole weight: 382.5. BOC Sciences 9
RG108 ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
RG108 RG108 is a DNA methyltransferase inhibitor with IC50 value of 115 nM. RG108 can enhance reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Synonyms: N-Phthalyl-L-tryptophan; RG-108; (2S)-2-(1,3-dioxoisoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid. Grades: >98%. CAS No. 48208-26-0. Molecular formula: C19H14N2O4. Mole weight: 334.33. BOC Sciences 9
RG 108 RG 108. Group: Biochemicals. Grades: Purified. CAS No. 48208-26-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
RG 108 (N-Phthalyl-L-tryptophan) A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming. Group: Biochemicals. Grades: Highly Purified. CAS No. 48208-26-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
RG13022 RG13022, a non-phenolic tyrphostin analog, is an epidermal growth factor (EGF) receptor tyrosine kinase inhibitor with potential antiproliferative effect. Synonyms: RG13022; RG 13022; RG-13022; 3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile; RG 13022; RG-13022. CAS No. 136831-48-6. Molecular formula: C16H14N2O2. Mole weight: 266.29. BOC Sciences 10
RG14620 RG14620 is a non-phenolic tyrphostin-class epidermal growth factor receptor (EGFR) inhibitor (IC50= 3 μM for HER 14 colony formation, and IC50= 1 pM for HER 14 DNA synthesis), with anti-proliferative effects on renal and bladder carcinoma cell lines. Synonyms: (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile; RG 14620; RG14620; RG-14620; TYRPHOSTIN RG 14620. CAS No. 136831-49-7. Molecular formula: C14H8Cl2N2. Mole weight: 275.13. BOC Sciences 10
RG2833 RGFP 109 is a histone deacetylase (HDAC) inhibitor that has shown to reverse FXN gene silencing in short-term studies of Friedreich ataxia (FRDA) patient cells. Synonyms: RG-2833; RG 2833; RG2833; RGFP-109; RGFP 109; RGFP109.; N-[6-(2-Aminophenylamino)-6-oxohexyl]-4-methylbenzamide. Grades: >98%. CAS No. 1215493-56-3. Molecular formula: C20H25N3O2. Mole weight: 339.43. BOC Sciences 10
RG3039 RG3039 is a potent DcpS inhibitor. It is used for the treatment for spinal muscular atrophy(SMA), which is caused by deletion or mutation of both copies of the SMN1 gene. It improves motor function in SMA mice. It also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models. It was developed by Repligen and now in Clinic Phase 1 with no progress. Uses: Rg3039 is used for the treatment for spinal muscular atrophy(sma). Synonyms: RG3039; RG 3039; RG-3039; PF06687859; PF 06687859; PF-06687859. 5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine;5-[[1-[(2,6-dichlorophenyl)methyl]piperidin-4-yl]methoxy]quinazoline-2,4-diamine. Grades: >98 %. CAS No. 1005504-62-0. Molecular formula: C21H23Cl2N5O. Mole weight: 432.35. BOC Sciences 9
RG-6080 Nacubactam, also known as RG-6080, FPI-1459, and OP-0595, is a beta-lactamase inhibitor used for treating bacterial infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RG-6080; RG 6080; RG6080; FPI-1459; FPI 1459; FPI1459; OP-0595; OP 0595; OP0595; Nacubactam. Product Category: Inhibitors. Appearance: Off-white to beige solid powder. CAS No. 1452458-86-4. Molecular formula: C9H16N4O7S. Mole weight: 324.31. Purity: >98%. IUPACName: (1R,2S,5R)-2-((2-aminoethoxy)carbamoyl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. Canonical SMILES: O=S(O)(ON1[C@]2([H])CC[C@@H](C(NOCCN)=O)[N@@](C2)C1=O)=O. Product ID: ACM1452458864. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
RG7-0099 RG7-0099 is a small-molecule and dual inhibitor of IDO1/TDO (IDO1 IC50 < 100nM while TDO IC50 < 100nM) , which modulate immunosuppressive effects. In preclinical models, it significantly reduced Kyn levels. RG7-0099 is potentially used in various cancers. Uses: Potential antitumor drug. Synonyms: RG7-0099; RG7 0099; RG70099. BOC Sciences 9
RG7090 RG7090 is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5). Synonyms: Basimglurant; CTEP Derivative; RG7090; RG 7090; RG-7090. Grades: >98%. CAS No. 802906-73-6. Molecular formula: C18H13ClFN3. Mole weight: 325.77. BOC Sciences 10
RG7129 Cas No. 1628077-06-4. BOC Sciences 10
RG7800 RG7800 is a selective Survival of motor neuron 1 protein (SMN1) stimulant and Survival of motor neuron 2 protein (SMN2) modulator originated by Roche. RG7800 shows excellent pharmacokinetic and in vivo efficacy and has a favorable safety profile. RG7800 can correct alternative splicing of the human. Phase I/II clinical trials for the treatment of Spinal muscular atrophyis on-going. Uses: Spinal muscular atrophy. Synonyms: RG7800; RG-7800; RG 7800; RO6885247; RO-6885247; RO 6885247. 2-(4-ethyl-6-methylpyrazolo[1,5-a]pyrazin-2-yl)-9-methyl-7-(1-methylpiperidin-4-yl)-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: 98%. CAS No. 1449598-06-4. Molecular formula: C24H28N6O. Mole weight: 416.52. BOC Sciences 8
RG7834 RG7834 is a highly selective and orally bioavailable HBV inhibitor, suppressing HBV antigens (both HBsAg and HBeAg) and virion production. Synonyms: RO 7020322; (6S)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydro-2h-pyrido[2,1-a]isoquinoline-3-carboxylic acid. Grades: ≥98% (HPLC). CAS No. 2072057-17-9. Molecular formula: C22H27NO6. Mole weight: 401.45. BOC Sciences 10
RGA-C11 It is a mild glucoside detergent that can be used as an alternative to GDN, digitalin and CHAPS. Due to the formation of small protein-detergent complexes (PDCs) with GPCRs and their enhanced stability, this detergent is conducive to the determination of protein structures, particularly for CryoEM-based structural study. Synonyms: resorcinarene-based amphiphile-C11. Grades: >99%. CAS No. 2390023-16-0. Molecular formula: C132H216O56. Mole weight: 2699.09. BOC Sciences 12
Rga I One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GCGAT↑CGC CGC↓TAGCG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Rhizoblum galegae. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1164RE. Creative Enzymes
RGB-1 RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 930455-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156228. MedChemExpress MCE
RGB-286638 RGB-286638 is a novel CDK inhibitor. It inhibited several tyrosine and serine/threonine non-CDK enzymes, i.e. GSK-3β, TAK1, AMPK, Jak2, MEK1. It demonstrated equimolar (50nM) activity in freshly isolated tumor cells from MM patients, while manifesting less cytotoxicity in healthy donor PBMCs. It reduced the phosphorylation of Rb at S807/811 in MM.1S and MM.1R cells, but had no effects on p-Rb S780. Synonyms: RGB-286638; RGB286638; RGB286638. Grades: >98%. CAS No. 784210-87-3. Molecular formula: C29H37Cl2N7O4. Mole weight: 618.55. BOC Sciences 10
RGB-286638 free base RGB-286638 is a multitargeted cyclin-dependent kinase inhibitor. RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs. GB-286638 treatment resulted in MM cytotoxicity in vitro associated with inhibition of MM tumor growth and prolonged survival in vivo. RGB-286638 displayed caspase-dependent apoptosis in both wt-p53 and mutant-p53 cells that was closely associated with the downregulation of RNA polymerase II phosphorylation and inhibition of transcription. RGB-286638 triggered p53 accumulation via nucleolar stress and loss of Mdm2, accompanied by induction of p53 DNA-binding activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RGB-286638, RGB 286638, RGB286638; RGB-286638 free base. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 784210-88-4. Molecular formula: C29H35N7O4. Mole weight: 545.64. Purity: >98%. IUPACName: 1-[3-[4-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea. Canonical SMILES: O=C(NN1CCOCC1)NC2=CC=CC(C3=C4C(C5=CC=C(CN6CCN(CCOC)CC6)C=C5)=NN3)=C2C4=O. Product ID: ACM784210884. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
RGB-286638 Free base RGB-286638 is a novel CDK inhibitor. It inhibited several tyrosine and serine/threonine non-CDK enzymes, i.e. GSK-3β, TAK1, AMPK, Jak2, MEK1. It demonstrated equimolar (50nM) activity in freshly isolated tumor cells from MM patients, while manifesting less cytotoxicity in healthy donor PBMCs. It reduced the phosphorylation of Rb at S807/811 in MM.1S and MM.1R cells, but had no effects on p-Rb S780. Synonyms: 1-[3-[4-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea; RGB 286638; RGB286638. Grades: >98%. CAS No. 784210-88-4. Molecular formula: C29H35N7O4. Mole weight: 545.63. BOC Sciences 8
RGD RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 99896-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0278. MedChemExpress MCE
RGD-4C RGD-4C preferentially binds to integrins αvβ3 and αvβ5, both of which are overexpressed in many cancers, such as non-small cell lung cancer, melanoma, and growing vessels. Synonyms: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); L-alanyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-arginyl-glycyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinyl-glycine (2->10),(4->8)-bis(disulfide); N-{[(1R,4S,7R,12R,15S,18R,21S,27S)-7-(L-Alanylamino)-15-benzyl-27-(3-carbamimidamidopropyl)-4,21-bis(carboxymethyl)-3,6,14,17,20,23,26,29-octaoxo-9,10,31,32-tetrathia-2,5,13,16,19,22,25,28-octaazabicyclo[16.11.4]tritriacont-12-yl]carbonyl}glycine. Grades: ≥95%. CAS No. 332179-76-7. Molecular formula: C42H60N14O16S4. Mole weight: 1145.29. BOC Sciences 6
RGD Negative Control It is the negative control of c(RGDfE). Synonyms: c(RADfE); cyclo[Ala-Asp-D-Phe-Glu-Arg]; cyclo[L-alanyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl-L-arginyl]. Grades: ≥95%. CAS No. 756500-24-0. Molecular formula: C27H38N8O9. Mole weight: 618.65. BOC Sciences 6
RGD peptide RGD peptide is an inhibitor of integrin-ligand interactions. Synonyms: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. Grades: 98%. CAS No. 114681-65-1. Molecular formula: C23H38N10O10. Mole weight: 614.61. BOC Sciences 8
RGD peptide (GRGDNP) RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 114681-65-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1740. MedChemExpress MCE
RGD-targeted Proapoptotic Peptide RGD-targeted Proapoptotic Peptide is RGD-4C conjugated to a full D proapoptotic peptide. Synonyms: RGD-4C-GG-(klaklak)2-NH2; H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-Gly-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); D-Lysine, L-alanyl-L-cysteinyl-L-α-aspartyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-L-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-, cyclic(2?10),(4?8)-bis(disulfide). Grades: ≥95%. CAS No. 2243207-09-0. Molecular formula: C116H199N35O31S4. Mole weight: 2708.34. BOC Sciences 6
RGD Trifluoroacetate RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 2378808-45-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0278A. MedChemExpress MCE
RGFP966 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
RGFP966 RGFP966 is a selective HDAC3 inhibitor. Systemic treatment with RGFP966 facilitates extinction in mice in a manner resistant to reinstatement. A single treatment of RGFP966 enhances extinction of a previously established cocaine-conditioned place preference, while simultaneously enhancing long-term object-location memory within subjects. During extinction consolidation, HDAC3 inhibition promotes a distinct pattern of histone acetylation linked to gene expression within the infralimbic cortex, hippocampus, and nucleus accumbens. Thus, the facilitated extinction of drug-seeking cannot be explained by adverse effects on performance. These results demonstrate that HDAC3 inhibition enhances the memory processes involved in extinction of drug-seeking behavior. Synonyms: RGFP966; RGFP 966; RGFP-966. Grades: 0.98. CAS No. 1357389-11-7. Molecular formula: C21H19FN4O. Mole weight: 362.4. BOC Sciences 10
rGO-NH-Carboimidazole rGO-NH-Carboimidazole. Uses: Designed for use in research and industrial production. Product Category: Graphene With High Quality. CAS No. 7440-44-0. Purity: 0.99. Product ID: ACM7440440-240. Alfa Chemistry — ISO 9001:2015 Certified. Categories: methane. Alfa Chemistry. 2
RGS1, His tagged human recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
RGS Proteins Inhibitor II, CCG-50014 (4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione) A cell-permeable thiadiazolidinedione compound that acts as a direct, potent, selective and cysteine-reactive irreversible inhibitor of RGS4 over other RGS proteins (IC50=0.03, 0.12, 3.5, 11, >200 and >200uM against RGS4, RGS19, RGS16, RGS8, RGS7 and RGS4Cys- using FCPIA assay, respectively). Shown to block RGS4-Ga0 interaction and repress Ga0-dependent membrane localization of RGS4 in HEK-293T cells with no effect on the intrinsic rate of GTP hydrolysis by Ga0. Suggested to interact with Cys107-RGS8 allosteric regulatory site and display minimal affinity towards papain (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
RGW2938 A phosphodiesterase inhibitor. Synonyms: RGW2938; RGW 2938; RGW-2938; 2(1H)?-Quinazolinone, 3,?4-dihydro-3-methyl-6-(1,?4,?5,?6-tetrahydro-6-oxo-3-pyridazinyl)?-. CAS No. 111786-07-3. Molecular formula: C13H14N4O2. Mole weight: 258.28. BOC Sciences 10
RGW 611 RGW 611 is an impurity of Nimorazole, which is an anti-infective agent against anaerobic bacteria and protozoa. Nimorazole is being researched for the treatment of head and neck cancer. Synonyms: 4-(2-(4-nitro-1H-imidazol-1-yl)ethyl)morpholine. CAS No. 6497-78-5. Molecular formula: C9H14N4O3. Mole weight: 226.236. BOC Sciences 8
RGX-104 RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abequolixron. CAS No. 610318-54-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111498A. MedChemExpress MCE
RGX-104 hydrochloride RGX-104 is an orally bioavailable liver X receptor agonist displaying immunomodulating and antineoplastic activity. Synonyms: RGX-104; 2-[3-[ (3R) -3-[[2-Chloro-3- (trifluoromethyl) phenyl]methyl- (2, 2-diphenylethyl) amino]butoxy]phenyl]acetic acid hydrochloride. CAS No. 610318-03-1. Molecular formula: C34H34Cl2F3NO3. Mole weight: 632.54. BOC Sciences 10
RGX-104 hydrochloride RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abequolixron hydrochloride. CAS No. 610318-03-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111498. MedChemExpress MCE
RH1 RH1 (NSC 697726) is a potent bioreductive agent with profound anti-cancer activity in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 697726. CAS No. 221635-42-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13741. MedChemExpress MCE
RH1 RH1 is a new bioreductive agent that is an excellent substrate for the two-electron reducing enzyme, NAD(P)H quinone oxidoreductase 1 (NQO1). In phase trials, RH1 was well tolerated with predictable and manageable toxicity. The MTD of 1430 μg/m(2)/day is the dose recommended for phase II trials. The biomarkers of DNA cross linking, DTD activity and NQO1 status have been validated and clinically developed. Synonyms: RH 1; RH-1; NSC697726; 2,5-di(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione. CAS No. 221635-42-3. Molecular formula: C12H14N2O3. Mole weight: 234.25. BOC Sciences 11
RH-5849 RH-5849 is an orally active agonist for non-steroidal ecdysteroid , which inhibits the larval growth of Plodia inferpuncteila in a dose-dependent manner. RH-5849 exhibits molting hormone activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112225-87-3. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g; 5 g. Product ID: HY-118541. MedChemExpress MCE
R(+)-HA-966 solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Rhacophorin-1 antimicrobial peptide precursor Rhacophorin-1 antimicrobial peptide precursor is an antibacterial peptide isolated from Rhacophorus feae. Synonyms: Ile-Gly-Pro-Met-Ile-Lys-Ile-Ala-Thr-Asn-Leu-Leu-Pro-Thr-Val-Ile-Cys-Lys-Ile-Phe-Lys-Lys-Cys. Grades: >96%. BOC Sciences 4
Rhacophorin-2 antimicrobial peptide precursor Rhacophorin-2 antimicrobial peptide precursor is an antibacterial peptide isolated from Rhacophorus feae. Synonyms: Thr-Leu-Lys-Lys-Ser-Leu-Leu-Ile-Leu-Phe-Phe-Leu-Gly-Met-Ile-Ser-Met-Ser-Leu-Cys-Gln. Grades: >96%. BOC Sciences 4
Rhamnetin Rhamnetin is a quercetin derivative found in Coriandrum sativum , inhibits secretory phospholipase A2 , with antioxidant and anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 90-19-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7036. MedChemExpress MCE
Rhamnetin analytical standard. Group: Chemical class. Alfa Chemistry Analytical Products
rhamnogalacturonan acetylesterase The degradation of rhamnogalacturonan by rhamnogalacturonases depends on the removal of the acetyl esters from the substrate. Group: Enzymes. Synonyms: RGAE. Enzyme Commission Number: EC 3.1.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3515; rhamnogalacturonan acetylesterase; EC 3.1.1.86; RGAE. Cat No: EXWM-3515. Creative Enzymes
rhamnogalacturonan endolyase The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168 and Aspergillus aculeatus. Group: Enzymes. Synonyms: rhamnogalacturonase B; α-L-rhamnopyranosyl-(1?4)-α-D-galactopyranosyluronide lyase; Rgase B; rhamnogalacturonan α-L-rhamnopyranosyl-(1,4)-α-D-galactopyranosyluronide lyase; RG-lyase; YesW; RGL4; Rgl11A; Rgl11Y; RhiE. Enzyme Commission Number: EC 4.2.2.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5099; rhamnogalacturonan endolyase; EC 4.2.2.23; rhamnogalacturonase B; α-L-rhamnopyranosyl-(1?4)-α-D-galactopyranosyluronide lyase; Rgase B; rhamnogalacturonan α-L-rhamnopyranosyl-(1,4)-α-D-galactopyranosyluronide lyase; RG-lyase; YesW; RGL4; Rgl11A; Rgl11Y; RhiE. Cat No: EXWM-5099. Creative Enzymes
rhamnogalacturonan exolyase The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168. Group: Enzymes. Synonyms: YesX. Enzyme Commission Number: EC 4.2.2.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5100; rhamnogalacturonan exolyase; EC 4.2.2.24; YesX. Cat No: EXWM-5100. Creative Enzymes
Rhamnogalacturonan - from potato BOC Sciences 12
Rhamnogalacturonan - from soy bean BOC Sciences 12
rhamnogalacturonan galacturonohydrolase The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus. Group: Enzymes. Synonyms: RG-galacturonohydrolase. Enzyme Commission Number: EC 3.2.1.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3856; rhamnogalacturonan galacturonohydrolase; EC 3.2.1.173; RG-galacturonohydrolase. Cat No: EXWM-3856. Creative Enzymes
rhamnogalacturonan hydrolase The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus. Group: Enzymes. Synonyms: rhamnogalacturonase A; RGase A; RG-hydrolase. Enzyme Commission Number: EC 3.2.1.171. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3854; rhamnogalacturonan hydrolase; EC 3.2.1.171; rhamnogalacturonase A; RGase A; RG-hydrolase. Cat No: EXWM-3854. Creative Enzymes
Rhamnogalacturonan Lyase from Cellvibrio japonicus, Recombinant Rhamnogalacturonan Lyase is an endo-1,4-α-rhamnogalacturonan lyase. This enzyme catalyses the following chemical reaction: Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end. Group: Enzymes. Synonyms: endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Enzyme Commission Number: EC 4.2.2.-. Purity: >90% as judged by SDS-PAGE. Rhamnogalacturonan Lyase. Mole weight: 79.6 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Cellvibrio japonicus. endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Cat No: NATE-1565. Creative Enzymes
Rhamnogalacturonan Lyase from Clostridium thermocellum, Recombinant Rhamnogalacturonan Lyase is an endo-1,4-α-rhamnogalacturonan lyase. This enzyme catalyses the following chemical reaction: Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end. Group: Enzymes. Synonyms: endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Enzyme Commission Number: EC 4.2.2.-. Purity: >90% as judged by SDS-PAGE. Rhamnogalacturonan Lyase. Mole weight: 76.1 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Clostridium thermocellum. endo-1,4-α-rhamnogalacturonan lyase; EC 4.2.2.-. Cat No: NATE-1564. Creative Enzymes
rhamnogalacturonan rhamnohydrolase The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus. Group: Enzymes. Synonyms: RG-rhamnohydrolase; RG α-L-rhamnopyranohydrolase. Enzyme Commission Number: EC 3.2.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3857; rhamnogalacturonan rhamnohydrolase; EC 3.2.1.174; RG-rhamnohydrolase; RG α-L-rhamnopyranohydrolase. Cat No: EXWM-3857. Creative Enzymes
Rhamnolipid Rhamnolipid is a versatile bioproduct widely used in the biomedical industry known for its exceptional surface-active and antimicrobial properties. Rhamnolipid has been extensively studied for its potential in studying various drug-resistant infections and diseases. Moreover, this natural surfactant exhibits promising potential as an eco-friendly alternative in pharmaceutical formulations and drug delivery systems. Synonyms: Rha-(rac)C10C10 rhamnolipid; mono-Rhamnolipid. Molecular formula: C26H48O9. Mole weight: 504.65. BOC Sciences
Rhamnolipid Rhamnolipid. Uses: Designed for use in research and industrial production. CAS No. 869062-42-0. Product ID: BBC869062420. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.

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